NCBI Conserved Domain Search

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

298-552

1.29e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 84.99 E-value: 1.29e-16

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 298 LLHIVQHQKTVSERQQQEKFEKMEQERLRQEKEEKARELERRRklEESETARQAELDRQATIY---AEQERMAMERNREL 374
Cdd:COG1196 231 LLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELR--LELEELELELEEAQAEEYellAELARLEQDIARLE 308

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 375 ERIRLEEKKRENERVRQEEIAMEISKIRELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEE 454
Cdd:COG1196 309 ERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL 388

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 455 ARQEQLRVLEEERARELERVRQEELERQHQMEILRQQEEDQKKKKLEKDREQREQQEAEELNRMIIEKEMKENKQKMIEE 534
Cdd:COG1196 389 LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL 468

                       250
                ....*....|....*...
gi 86562857 535 KNKRKMLEKEMEDRQNAI 552
Cdd:COG1196 469 LEEAALLEAALAELLEEL 486

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

318-617

2.52e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 64.70 E-value: 2.52e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    318 EKMEQ-ERLRQEKEEKARELERRRKLEESE-TARQAELDRQATIYAEQERMAMERNRELERI--RLEEKKRENERVRQ-- 391
Cdd:TIGR02169  195 EKRQQlERLRREREKAERYQALLKEKREYEgYELLKEKEALERQKEAIERQLASLEEELEKLteEISELEKRLEEIEQll 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    392 EEIAMEISKIRELERLQLerQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLRVLEEERAREL 471
Cdd:TIGR02169  275 EELNKKIKDLGEEEQLRV--KEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRR 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    472 ERVRQEELERQHQMEILRQQ-EEDQKKKKLEKDREQREQQEAEELNRMIieKEMKENKQKMIEEKNKRKMlekEMEDRQN 550
Cdd:TIGR02169  353 DKLTEEYAELKEELEDLRAElEEVDKEFAETRDELKDYREKLEKLKREI--NELKRELDRLQEELQRLSE---ELADLNA 427

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 86562857    551 AIyeeeerriaEEERRKQIEIEERRR-IQQQIMIATEERSRLDA-MEREREMLRQIKES----EKQRKELERQ 617
Cdd:TIGR02169  428 AI---------AGIEAKINELEEEKEdKALEIKKQEWKLEQLAAdLSKYEQELYDLKEEydrvEKELSKLQRE 491

growth_prot_Scy

NF041483

polarized growth protein Scy;

307-461

2.78e-05

polarized growth protein Scy;

Pssm-ID: 469371 [Multi-domain] Cd Length: 1293 Bit Score: 48.28 E-value: 2.78e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   307 TVSERQQQEKFEKM--EQERLRQEKEEKAREL---------ERRRKLEESETARQAELDRQAT----------------- 358
Cdd:NF041483  516 TTLRRQAEETLERTraEAERLRAEAEEQAEEVraaaeraarELREETERAIAARQAEAAEELTrlhteaeerltaaeeal 595

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   359 --IYAEQERMAMERNRELERIRLEEKKR----------ENERVRqEEIAMEISKIR----------------ELERLQLE 410
Cdd:NF041483  596 adARAEAERIRREAAEETERLRTEAAERirtlqaqaeqEAERLR-TEAAADASAARaegenvavrlrseaaaEAERLKSE 674

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   411 RQRKNERVRQEL---------EAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLR 461
Cdd:NF041483  675 AQESADRVRAEAaaaaervgtEAAEALAAAQEEAARRRREAEETLGSARAEADQERERAR 734

ChtBD2

smart00494

Chitin-binding domain type 2;

692-744

1.02e-03

Chitin-binding domain type 2;

Pssm-ID: 214696 [Multi-domain] Cd Length: 49 Bit Score: 37.81 E-value: 1.02e-03

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 86562857    692 GECElkYDVDSFCAHPRSPSMYLQCAPlygrlGRWTERYCPDTLIFIVSIGRC 744
Cdd:smart00494   1 NECP--GRGDGLYPHPTDCSKYYQCSN-----GRPIVGSCPAGLVFNPATQTC 46

GBP_C

cd16269

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...

419-549

2.63e-03

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal domain. Guanylate-binding proteins (GBPs) are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range), are stable in their absence, and have a high turnover GTPase. In addition to binding GDP/GTP, they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP, but also to GMP. This C-terminal domain has been shown to mediate inhibition of endothelial cell proliferation by inflammatory cytokines.

Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 41.02 E-value: 2.63e-03

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 419 RQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQlrvleeerarelervrqeelERQHQmEILRQQEE--DQK 496
Cdd:cd16269 191 QALTEKEKEIEAERAKAEAAEQERKLLEEQQRELEQKLEDQ--------------------ERSYE-EHLRQLKEkmEEE 249

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....
gi 86562857 497 KKKLEKDreqreqqeaeelNRMIIEKEMKENKQKMIEE-KNKRKMLEKEMEDRQ 549
Cdd:cd16269 250 RENLLKE------------QERALESKLKEQEALLEEGfKEQAELLQEEIRSLK 291

Name

Accession

Description

Interval

E-value

DUF5401

pfam17380

Family of unknown function (DUF5401); This is a family of unknown function found in ...

22-749

0e+00

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 1106.72 E-value: 0e+00

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    22 VIFTSERCNRVTYGLRTVNGDPSRYKQCGPSGRVWIVPCAPQMTFDPEDRVCKERLDSRIVKPMRKYETSRTIITTPAPI 101
Cdd:pfam17380   1 VIFTSERCNRVTYGLRTVNGDPSRYKQCGPSGRVWIVPCAPQMTFDPEDRVCKERLDSRVFKPMRKYETAKTIITTPAPI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   102 PSSYPVSAEVIAPGAPAAshaAPEEFVFSTIRPKSRKPKAKTRGKFRKTTTAMIQTTTP-MTVESFESMEMTTTPKIVIF 180
Cdd:pfam17380  81 PSSYPVSAEVSPPGAPAA---APEEFVFSTIRPKSRKPKARTRGKKRKTTTTMIQTTTPmMVTTSSSALEMTTTPKIVIF 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   181 ASKKNMNNTNRSGESRTQlIRNRNRERGNAPAFTRPGRVRTTTPMSVTHATRFVPGIQHKvTVAPKEVQGMPHTLAPYEK 260
Cdd:pfam17380 158 ASKKNASGGNRSGEQRKQ-IQLIRRRRGNHSAFTRPGRPRTTTPMPVTHATRFVPGIQMS-TVAPKEVQGMPHTLAPYEK 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   261 MDRRPDSFGV-EELTTMTPEYTVRYNGQTMTENEFLNQLLHIVQHQKTVSERQQQEKFEKMEQERLRQEKEEKARELERR 339
Cdd:pfam17380 236 MERRKESFNLaEDVTTMTPEYTVRYNGQTMTENEFLNQLLHIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERR 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   340 RKLEESETARQAELDRQATIYAEQERMAMERNRELERIRLEEKKRENERVRQEEIAMEISKIRELERLQLERQRKNERVR 419
Cdd:pfam17380 316 RKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKRELERIRQEEIAMEISRMRELERLQMERQQKNERVR 395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   420 QELEAARKYKLQEEERQRKIQQQKVEMEQIR-QQEEARQEQLRVLEEERARELERVRQEELERQHQMEILRQQEEDQKKK 498
Cdd:pfam17380 396 QELEAARKVKILEEERQRKIQQQKVEMEQIRaEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRK 475

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   499 KLEKDREQREQQEAEELNRMIIEKEMKENKQKMIEEKNKRKMLEKEMEDRQNAIYEEEERRIAEEERRKQIEIEERRRIQ 578
Cdd:pfam17380 476 KLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQ 555

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   579 QQIMIATEERSRLDAMEREREMLRQIKESEKQRKELErqellATTPITTIKPIYRPDISEYRPPDVESHMIRFTTQSPEW 658
Cdd:pfam17380 556 EQMRKATEERSRLEAMEREREMMRQIVESEKARAEYE-----ATTPITTIKPIYRPRISEYQPPDVESHMIRFTTQSPEW 630

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   659 ATPSP-TWNPAWNTVTAEEETPGIPIIHSQCQVNGECELKYDVDSFCAHPRSPSMYLQCAPLYGRLGRWTERYCPDTLIF 737
Cdd:pfam17380 631 ATPSPaTWNPEWNTVTAEEETPGIPIIHSQCQVNGECELKYDSDSFCAHPSNPSMYLQCAPLYGRLGRWTERHCPDTLIF 710

                         730
                  ....*....|..
gi 86562857   738 IVSIGRCEKGEE 749
Cdd:pfam17380 711 IVSIGRCEKGEE 722

PTZ00121

MAEBL; Provisional

305-623

5.42e-21

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 99.83 E-value: 5.42e-21

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   305 QKTVSERQQQEKFEKMEQERLRQEKEEKARELERRRKLEESETARQAELDRQA--TIYAEQERMAMERNRELERIRLEEK 382
Cdd:PTZ00121 1490 KKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAeeKKKADELKKAEELKKAEEKKKAEEA 1569

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   383 KRENER----VRQEEIAMEISKIRELERLQL---ERQRKNERVRQELEA---ARKYKLQEEERQRKIQQQKVEMEQIRQQ 452
Cdd:PTZ00121 1570 KKAEEDknmaLRKAEEAKKAEEARIEEVMKLyeeEKKMKAEEAKKAEEAkikAEELKKAEEEKKKVEQLKKKEAEEKKKA 1649

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   453 EEARQEQlrvleEERARELERVRQEELERQHQMEILRQQEEDQKKKKLEKDREQREQQEAEELNRMIIEKEMKENKQKMI 532
Cdd:PTZ00121 1650 EELKKAE-----EENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKA 1724

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   533 EEKNKRKMLE---KEMEDRQNAiyeeeerriaeeeRRKQIEIEERRRIQQqimIATEERSRLDAMEREREMLrqIKESEK 609
Cdd:PTZ00121 1725 EEENKIKAEEakkEAEEDKKKA-------------EEAKKDEEEKKKIAH---LKKEEEKKAEEIRKEKEAV--IEEELD 1786

                         330
                  ....*....|....
gi 86562857   610 QRKELERQELLATT 623
Cdd:PTZ00121 1787 EEDEKRRMEVDKKI 1800

PTZ00121

MAEBL; Provisional

305-618

4.69e-17

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 87.12 E-value: 4.69e-17

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   305 QKTVSERQQQEKFEKMEQERLRQEKEEKARELERRRKLEESETARQAELD-RQATIYAEQERMAMERNRELERIRLEEKK 383
Cdd:PTZ00121 1442 EAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKaEEAKKKADEAKKAAEAKKKADEAKKAEEA 1521

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   384 RENERVRQEEIAMEISKIRELERL-QLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEmeQIRQQEEAR-QEQLR 461
Cdd:PTZ00121 1522 KKADEAKKAEEAKKADEAKKAEEKkKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAE--EAKKAEEARiEEVMK 1599

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   462 VLEEERARELERVRQEELERQhQMEILRQQEEDQKKKKLEKDREQREQQEAEELNRMIIEKEMK--ENKQKMIEEKNKRK 539
Cdd:PTZ00121 1600 LYEEEKKMKAEEAKKAEEAKI-KAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKaaEEAKKAEEDKKKAE 1678

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 86562857   540 MLEKEMEDRQNAiyeeeerriaeeERRKQIEIEERRRIQQQIMIATEERSRLDAMEREREMlRQIKESEKQRKELERQE 618
Cdd:PTZ00121 1679 EAKKAEEDEKKA------------AEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEE-NKIKAEEAKKEAEEDKK 1744

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

298-552

1.29e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 84.99 E-value: 1.29e-16

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 298 LLHIVQHQKTVSERQQQEKFEKMEQERLRQEKEEKARELERRRklEESETARQAELDRQATIY---AEQERMAMERNREL 374
Cdd:COG1196 231 LLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELR--LELEELELELEEAQAEEYellAELARLEQDIARLE 308

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 375 ERIRLEEKKRENERVRQEEIAMEISKIRELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEE 454
Cdd:COG1196 309 ERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL 388

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 455 ARQEQLRVLEEERARELERVRQEELERQHQMEILRQQEEDQKKKKLEKDREQREQQEAEELNRMIIEKEMKENKQKMIEE 534
Cdd:COG1196 389 LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL 468

                       250
                ....*....|....*...
gi 86562857 535 KNKRKMLEKEMEDRQNAI 552
Cdd:COG1196 469 LEEAALLEAALAELLEEL 486

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

311-621

1.37e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 84.99 E-value: 1.37e-16

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 311 RQQQEKFEKMEQERLRQEKEEKARELER-RRKLEESETARQAELDRQATIYAEQERMAMERNREleRIRLEEKKRENERV 389
Cdd:COG1196 216 RELKEELKELEAELLLLKLRELEAELEElEAELEELEAELEELEAELAELEAELEELRLELEEL--ELELEEAQAEEYEL 293

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 390 RQEEIAMEISKIRELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLRVLEEERAR 469
Cdd:COG1196 294 LAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE 373

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 470 ELERVRQEELERQHQMEILRQQEEDQKKKKLEKDREQREQQEAEELNRMIIEKEmkENKQKMIEEKNKRKMLEKEMEDRQ 549
Cdd:COG1196 374 LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELE--EALAELEEEEEEEEEALEEAAEEE 451

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 86562857 550 NAIYEEEERRIAEEERRKQIEIEERRRIQQQIMIATEERSRLDAMEREREMLRQIKESEKQRKELERQELLA 621
Cdd:COG1196 452 AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA 523

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

323-619

5.24e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 83.06 E-value: 5.24e-16

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 323 ERLRQEKE--EKAREL---ERRRKLEESETARQAELDRQATIYAEQERMAMERNRELERIRLEEKKRENERVRQEEIAME 397
Cdd:COG1196 203 EPLERQAEkaERYRELkeeLKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELE 282

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 398 ISK--------IRELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLRvleeeRAR 469
Cdd:COG1196 283 LEEaqaeeyelLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELE-----EAE 357

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 470 ELERVRQEELERQHQMEILRQQEEDQKKKKLEKDREQREQQEAEELNRMIIEKEMKENKQKMIEEKNKRKMLEKEMEDRQ 549
Cdd:COG1196 358 AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEE 437

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 550 NAIYEEEERRIAEEERRKQIEIEERRRIQQQIMIATEERSRLDAMEREREMLRQIKESEKQRKELERQEL 619
Cdd:COG1196 438 EEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFL 507

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

314-621

7.31e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 82.68 E-value: 7.31e-16

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 314 QEKFEKMEQ--ERLrqekEEKARELERRRK-LE-ESETARQA-ELDRQATIYAEQERMAMERNRELERIRLEEKKRENER 388
Cdd:COG1196 178 ERKLEATEEnlERL----EDILGELERQLEpLErQAEKAERYrELKEELKELEAELLLLKLRELEAELEELEAELEELEA 253

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 389 VRQEEIAMEISKIRELERLQLERQRKnervRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLrvleeera 468
Cdd:COG1196 254 ELEELEAELAELEAELEELRLELEEL----ELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEEL-------- 321

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 469 relervrQEELERQHQMEILRQQEEDQKKKKLEKdreqreqqeaeelnrmiIEKEMKENKQKMIEEKNKRKMLEKEMEDR 548
Cdd:COG1196 322 -------EEELAELEEELEELEEELEELEEELEE-----------------AEEELEEAEAELAEAEEALLEAEAELAEA 377

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 86562857 549 QNAIyeeeERRIAEEERRKQIEIEERRRIQQQIMIATEERSRLDAMEREREMLRQIKESEKQRKELERQELLA 621
Cdd:COG1196 378 EEEL----EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

295-549

8.89e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 82.29 E-value: 8.89e-16

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 295 LNQLLHIVQHQKTVSERQQQEKFEKMEQERLRQEKEEK------ARELERRRKLEESETARQAELDRQATIYAEQERMAM 368
Cdd:COG1196 244 LEAELEELEAELEELEAELAELEAELEELRLELEELELeleeaqAEEYELLAELARLEQDIARLEERRRELEERLEELEE 323

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 369 ERNRELERIRLEEKKRENERVRQEEIAMEISKIRELERLQLERQRKNERVRQELEAA--RKYKLQEEERQRKIQQQKVEM 446
Cdd:COG1196 324 ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEleELAEELLEALRAAAELAAQLE 403

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 447 EQIRQQEEARQEQLRVLEEERARELERVRQEELERQHQMEILRQQEEDQKKKKLEKDREQREQQEAEELNRmiIEKEMKE 526
Cdd:COG1196 404 ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL--LEAALAE 481

                       250       260
                ....*....|....*....|...
gi 86562857 527 NKQKMIEEKNKRKMLEKEMEDRQ 549
Cdd:COG1196 482 LLEELAEAAARLLLLLEAEADYE 504

PTZ00121

MAEBL; Provisional

302-618

1.30e-15

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 82.11 E-value: 1.30e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   302 VQHQKTVSERQQQEKFEKMEQERLRQE--------KEEKARELERRRKLEE---SETARQAELDRQAtiyaEQERMAMER 370
Cdd:PTZ00121 1160 AEDARKAEEARKAEDAKKAEAARKAEEvrkaeelrKAEDARKAEAARKAEEerkAEEARKAEDAKKA----EAVKKAEEA 1235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   371 NRELERIRLEEKKRENERVRQEEIAMEISKIRELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIR 450
Cdd:PTZ00121 1236 KKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAK 1315

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   451 QQEEARQEqlrvleEERARELERVRQEELERQHQMEILRQQEEDQKKKKLEKDREQREQQEAEELNrmiiEKEMKENKQK 530
Cdd:PTZ00121 1316 KADEAKKK------AEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEE----AKKKADAAKK 1385

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   531 MIEEKNKRKMLEKEMEDRQNAIYEEEERRIAEEERRKQIEIEERRRIQQQIMIATEERSRLDAMEREREMLRQIKESEKQ 610
Cdd:PTZ00121 1386 KAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKK 1465


                  ....*...
gi 86562857   611 RKELERQE 618
Cdd:PTZ00121 1466 AEEAKKAD 1473

PTZ00121

MAEBL; Provisional

303-618

1.71e-15

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 81.73 E-value: 1.71e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   303 QHQKTVSERQQQEKFEKMEQERLRQEKEekaRELERRRKLEESETARQAEldRQATIYAEQERMAmERNRELERIRLEEK 382
Cdd:PTZ00121 1221 EDAKKAEAVKKAEEAKKDAEEAKKAEEE---RNNEEIRKFEEARMAHFAR--RQAAIKAEEARKA-DELKKAEEKKKADE 1294

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   383 KRENERVRQEEiamEISKIRELERLQLERQRKNERVRQELEAARKyklQEEERQRKIQQQKVEMEQIRQQEEARQEQLRV 462
Cdd:PTZ00121 1295 AKKAEEKKKAD---EAKKKAEEAKKADEAKKKAEEAKKKADAAKK---KAEEAKKAAEAAKAEAEAAADEAEAAEEKAEA 1368

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   463 LEEERARELER--VRQEELERQHQMEILRQQEEDQKKKKLEKDREQREQQEAEELNRMIIEKEMKENKQKMIEEKNKRKM 540
Cdd:PTZ00121 1369 AEKKKEEAKKKadAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADE 1448

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 86562857   541 LEKEMEDRQNAIYEEEERRIAEEERRKQIEIEERRRiqqqimiATEERSRLDAMEREREMLRQIKESEKQRKELERQE 618
Cdd:PTZ00121 1449 AKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKK-------ADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAE 1519

PTZ00121

MAEBL; Provisional

306-618

5.97e-15

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 80.19 E-value: 5.97e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   306 KTVSERQQQEKFEKMEQERLRQE--KEEKARELERRRKLEES---ETARQAELDRQA--TIYAEQERMAmERNRELERIR 378
Cdd:PTZ00121 1128 RKAEEARKAEDARKAEEARKAEDakRVEIARKAEDARKAEEArkaEDAKKAEAARKAeeVRKAEELRKA-EDARKAEAAR 1206

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   379 LEEKKRENERVRQEEIAMEISKIRELERLQ--------LERQRKNERVRQELEA-----ARKYKLQEEERQRKIQQQKvE 445
Cdd:PTZ00121 1207 KAEEERKAEEARKAEDAKKAEAVKKAEEAKkdaeeakkAEEERNNEEIRKFEEArmahfARRQAAIKAEEARKADELK-K 1285

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   446 MEQIRQQEEARQ-EQLRVLEEERARELERVRQEELERQHQmEILRQQEEDQKK--KKLEKDREQREQQEAEELNRMIIEK 522
Cdd:PTZ00121 1286 AEEKKKADEAKKaEEKKKADEAKKKAEEAKKADEAKKKAE-EAKKKADAAKKKaeEAKKAAEAAKAEAEAAADEAEAAEE 1364

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   523 EMKENKQKMIEEKNKRKMLEKEMEDRQNAIYEEEERRIAEEERRKQIEIEERRRIQQQIMIATEERSRLDAMEREREMLR 602
Cdd:PTZ00121 1365 KAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAK 1444

                         330
                  ....*....|....*.
gi 86562857   603 QIKESEKQRKELERQE 618
Cdd:PTZ00121 1445 KADEAKKKAEEAKKAE 1460

TPH

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...

310-620

6.79e-15

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.

Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 77.27 E-value: 6.79e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   310 ERQQQEKFEKMEQERLRQEKEEKARELERRRKLEEsETARQAELDRQATIYAEQERMAMERNRELERIRLEEKKRENERV 389
Cdd:pfam13868  25 DAQIAEKKRIKAEEKEEERRLDEMMEEERERALEE-EEEKEEERKEERKRYRQELEEQIEEREQKRQEEYEEKLQEREQM 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   390 RQEEIAMEISKIRELERLQLERQRKNERVRQELEAARKYKLQEEERQR----KIQQQKVEMEQIRQQEEARQEQLRVLEE 465
Cdd:pfam13868 104 DEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEReedeRILEYLKEKAEREEEREAEREEIEEEKE 183

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   466 ERARELERVRQEELERQHQMEILR----QQEEDQKKKKLEKDREQREQQEAEELNR----MIIEKEMKENKQKMIEEKNK 537
Cdd:pfam13868 184 REIARLRAQQEKAQDEKAERDELRaklyQEEQERKERQKEREEAEKKARQRQELQQareeQIELKERRLAEEAEREEEEF 263

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   538 RKMLEKEMEDRQnaiyeeeerrIAEEERRKQIEIEERRRIQQQIMIATEERSRLDAMEREREMLRQIKESEKQRKEL--- 614
Cdd:pfam13868 264 ERMLRKQAEDEE----------IEQEEAEKRRMKRLEHRRELEKQIEEREEQRAAEREEELEEGERLREEEAERRERiee 333


                  ....*.
gi 86562857   615 ERQELL 620
Cdd:pfam13868 334 ERQKKL 339

SMC_N

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

305-616

3.67e-14

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 77.32 E-value: 3.67e-14

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    305 QKTVSERQQQEKFEKMEQERLRQEKEEKARELERRRKLEESETARQAELDRQATIYAEQERMAMERNRELERIRLEEKKR 384
Cdd:pfam02463  673 KELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEE 752

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    385 ENERVRQEEIAMEISKIRELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLrvle 464
Cdd:pfam02463  753 EKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEE---- 828

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    465 eerareleRVRQEELERQHQM--EILRQQEEDQKKKKLEKDREQREQQEAEELNRMIIEKEMKENKQKMIEEKNKrKMLE 542
Cdd:pfam02463  829 --------KIKEEELEELALElkEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKE-KEEK 899

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 86562857    543 KEMEDRQNAIYEEEERRIAEEERRKQIEIEERRRIQQQIMIATEERSRLDAMEREREMLRQIKESEKQRKELER 616
Cdd:pfam02463  900 KELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELG 973

PTZ00121

MAEBL; Provisional

303-617

1.19e-13

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 75.95 E-value: 1.19e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   303 QHQKTVSERQQQEKFEKMEQERLRQEKEEKARELERRRKLEESETARQAELDRQAtiyaeQERMAMERNRELERIRLEEK 382
Cdd:PTZ00121 1094 EEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKA-----EDAKRVEIARKAEDARKAEE 1168

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   383 KRENERVRQEEIAMEISKIRELERLqlerqRKNERVRQeLEAARKYklqEEERQ----RKIQQQKvEMEQIRQQEEARQE 458
Cdd:PTZ00121 1169 ARKAEDAKKAEAARKAEEVRKAEEL-----RKAEDARK-AEAARKA---EEERKaeeaRKAEDAK-KAEAVKKAEEAKKD 1238

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   459 QLRVLEEERARELERVRQEELERQHQM---------EILRQQEEDQK---KKKLEKDREQREQQEAEELNRMIIE-KEMK 525
Cdd:PTZ00121 1239 AEEAKKAEEERNNEEIRKFEEARMAHFarrqaaikaEEARKADELKKaeeKKKADEAKKAEEKKKADEAKKKAEEaKKAD 1318

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   526 ENKQKMIEEKNKRKMLEKEMEDRQNAiyeEEERRIAEEERRKQIEIEERRRIQQQIMiATEERSRLDAMEREREMLRQIK 605
Cdd:PTZ00121 1319 EAKKKAEEAKKKADAAKKKAEEAKKA---AEAAKAEAEAAADEAEAAEEKAEAAEKK-KEEAKKKADAAKKKAEEKKKAD 1394

                         330
                  ....*....|..
gi 86562857   606 ESEKQRKELERQ 617
Cdd:PTZ00121 1395 EAKKKAEEDKKK 1406

SMC_N

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

292-620

5.43e-13

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 73.47 E-value: 5.43e-13

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    292 NEFLNQLLHIVQHQKTvserqqQEKFEKMEQERLRQEKEEKARELERRRKLEESETARQAELDRQATIYAEQErmamERN 371
Cdd:pfam02463  685 AESELAKEEILRRQLE------IKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEE----EEK 754

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    372 RELERIRLEEKKRENErvrQEEIAMEISKIRELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQ 451
Cdd:pfam02463  755 SRLKKEEKEEEKSELS---LKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIK 831

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    452 QEEARQEQLRVLEEERARELERVRQEELERQHQMEILRQQEEDQKKKKLEKDREQREQQEAEELNRMIIEKE-------M 524
Cdd:pfam02463  832 EEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEeesqklnL 911

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    525 KENKQKMIEEKNKRKMLEKEMEDRQNAIYEEEERRIAEEERR-KQIEIEERRRIQQQIMIATEERSRLDAMEREREMLRQ 603
Cdd:pfam02463  912 LEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENnKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYN 991

                          330
                   ....*....|....*..
gi 86562857    604 IKESEKQRKELERQELL 620
Cdd:pfam02463  992 KDELEKERLEEEKKKLI 1008

DUF4670

pfam15709

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...

311-501

2.39e-12

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.

Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 70.75 E-value: 2.39e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   311 RQQQEKFEKMEQERLRQEKEEkarelERRRKLEESETARQAEldrqatiyaeqERMAMERNRELERIRLEEKKRENERVR 390
Cdd:pfam15709 339 RAERAEMRRLEVERKRREQEE-----QRRLQQEQLERAEKMR-----------EELELEQQRRFEEIRLRKQRLEEERQR 402

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   391 QEEiameiskirELERLQLERQRKNERVRQELEAARKyKLQeeERQRKIQQ---QKVEMEQIRQQEEARQ---EQLRVLE 464
Cdd:pfam15709 403 QEE---------EERKQRLQLQAAQERARQQQEEFRR-KLQ--ELQRKKQQeeaERAEAEKQRQKELEMQlaeEQKRLME 470

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 86562857   465 EERARELERVRQ---EELERQHQMEILRQQEEDQKKKKLE 501
Cdd:pfam15709 471 MAEEERLEYQRQkqeAEEKARLEAEERRQKEEEAARLALE 510

PTZ00121

MAEBL; Provisional

282-619

2.91e-12

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 71.33 E-value: 2.91e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   282 VRYNGQTMTENEFLNQLLHIVQHQKTVSERQQQEKFEKMEQERlrqeKEEKARELERRRKLEE----SETARQAELDRQA 357
Cdd:PTZ00121 1248 ERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKK----KADEAKKAEEKKKADEakkkAEEAKKADEAKKK 1323

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   358 TIYAEQERMAMERNRELERIRLEEKKRENERVRQEEIAMEiSKIRELERLQLERQRKNERVRQELEAARKyklqEEERQR 437
Cdd:PTZ00121 1324 AEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAE-EKAEAAEKKKEEAKKKADAAKKKAEEKKK----ADEAKK 1398

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   438 KIQQQKVEMEQIRQQEEARQEQLRVLEEERARELERVRQEELERQHQMEILRQQEEDQKKKKLEKDREQREQQEAEELNR 517
Cdd:PTZ00121 1399 KAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKK 1478

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   518 MIIEKEMKENKQKMIEEKNKRKMLEKEMEDRQNAIYEEEERRIAEEERRKQieIEERRRIQQqiMIATEERSRLDAMERE 597
Cdd:PTZ00121 1479 AEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKK--AEEAKKADE--AKKAEEKKKADELKKA 1554

                         330       340
                  ....*....|....*....|....
gi 86562857   598 REMLR--QIKESEKQRKELERQEL 619
Cdd:PTZ00121 1555 EELKKaeEKKKAEEAKKAEEDKNM 1578

SMC_N

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

283-620

3.15e-12

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 70.77 E-value: 3.15e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    283 RYNGQTMTENEFLNQL---------LHIVQHQKtVSERQQQEKfekmEQERLRQEKE-----EKARELERRRKLEESETA 348
Cdd:pfam02463  110 YINGKNVTKKEVAELLesqgispeaYNFLVQGG-KIEIIAMMK----PERRLEIEEEaagsrLKRKKKEALKKLIEETEN 184

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    349 RQAELDRQATIYAEQERMAMERNRELeriRLEEKKRENERVRQEEIAMEISKIRELERLQLERQRKNERvrQELEAARKY 428
Cdd:pfam02463  185 LAELIIDLEELKLQELKLKEQAKKAL---EYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQ--EEIESSKQE 259

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    429 KLQEEERQRKIQQQKVEMEQIRQQEEARQEQLrvleeERARELERVRQEELERQHQMEILRQQEEDQKKKKLEKDREQRE 508
Cdd:pfam02463  260 IEKEEEKLAQVLKENKEEEKEKKLQEEELKLL-----AKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEK 334

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    509 QQEAEELNRMIIEKEMKENKQKMIEEKNKRKMLEKEMEDRQNAIYEEEERRIAEEERRKQIEIEERRRIQQQImiatEER 588
Cdd:pfam02463  335 EEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEA----QLL 410

                          330       340       350
                   ....*....|....*....|....*....|..
gi 86562857    589 SRLDAMEREREMLRQIKESEKQRKELERQELL 620
Cdd:pfam02463  411 LELARQLEDLLKEEKKEELEILEEEEESIELK 442

PTZ00121

MAEBL; Provisional

305-618

7.32e-12

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 69.78 E-value: 7.32e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   305 QKTVSERQQQEKFEKMEQERlRQEKEEKARELERRRKLEESETARQAEldrQATIYAEQERMAMERNRELERIRL---EE 381
Cdd:PTZ00121 1335 KKKAEEAKKAAEAAKAEAEA-AADEAEAAEEKAEAAEKKKEEAKKKAD---AAKKKAEEKKKADEAKKKAEEDKKkadEL 1410

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   382 KKRENERVRQEEI---AMEISKIRELERlQLERQRKNERVRQELEAARKYK--LQEEERQRKIQQQKVEMEQIRQQEEAR 456
Cdd:PTZ00121 1411 KKAAAAKKKADEAkkkAEEKKKADEAKK-KAEEAKKADEAKKKAEEAKKAEeaKKKAEEAKKADEAKKKAEEAKKADEAK 1489

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   457 ---QEQLRVLEEERARELERVRQEEL---ERQHQMEILRQQEEDQKKKKLEKDREQREQQEAEELNRMIIEKEMKENKQK 530
Cdd:PTZ00121 1490 kkaEEAKKKADEAKKAAEAKKKADEAkkaEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEA 1569

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   531 MIEEKNKRKMLEKEMEDRQ---------NAIYEEEERRIAEEERRKQ----------IEIEERRRIQQQIMIATEERSRL 591
Cdd:PTZ00121 1570 KKAEEDKNMALRKAEEAKKaeearieevMKLYEEEKKMKAEEAKKAEeakikaeelkKAEEEKKKVEQLKKKEAEEKKKA 1649

                         330       340
                  ....*....|....*....|....*..
gi 86562857   592 DAMEREREMLRQIKESEKQRKELERQE 618
Cdd:PTZ00121 1650 EELKKAEEENKIKAAEEAKKAEEDKKK 1676

SMC_N

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

317-639

1.02e-11

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 69.23 E-value: 1.02e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    317 FEKMEQERLRQEKEEKARELERRRKLEESETARQAELDRQATIYAEQERMAMERNRELERIRLEEKKRENERVRQEEIAM 396
Cdd:pfam02463  625 VEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKK 704

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    397 EISKIRELERLQLERQRKNERVRQELEaarkyKLQEEERQRKIQQQKVEMEQirqqEEARQEQLRVLEEERARELERVRQ 476
Cdd:pfam02463  705 EQREKEELKKLKLEAEELLADRVQEAQ-----DKINEELKLLKQKIDEEEEE----EEKSRLKKEEKEEEKSELSLKEKE 775

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    477 EELERQHQMEILRQQEEDQKKKKLEKDREQREQQEAEELNRMIIEKEMKENKQKMIEEKNKRKMLEKEMEDRQNAIyeEE 556
Cdd:pfam02463  776 LAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKL--AE 853

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    557 ERRIAEEERRKQIEIEERRRIQQQIMIATEERSRLDAMEREREMLRQIKESEKQRKELERQELLATTPITTIKPIYRPDI 636
Cdd:pfam02463  854 EELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKY 933


                   ...
gi 86562857    637 SEY 639
Cdd:pfam02463  934 EEE 936

PTZ00121

MAEBL; Provisional

303-607

1.21e-11

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 69.40 E-value: 1.21e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   303 QHQKTVSERQQQEKFEKMEQERLRQEKEEKAREL-----ERRRKLEESETARQAELDRQATIYAEQERMAMERNRELERI 377
Cdd:PTZ00121 1287 EEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAkkkaeEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKA 1366

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   378 RLEEKKRENERVRQEEI---AMEISKIRELERLQLERQRKNERVRQELEAARKyklqEEERQRKIQQQKVEMEQIRQQEE 454
Cdd:PTZ00121 1367 EAAEKKKEEAKKKADAAkkkAEEKKKADEAKKKAEEDKKKADELKKAAAAKKK----ADEAKKKAEEKKKADEAKKKAEE 1442

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   455 ARQEQLRVLEEERARELERVRQEELERQHQMEILRQQEEDQKKKKLEKDREQREQQEAEElnRMIIEKEMKENKQKMIEE 534
Cdd:PTZ00121 1443 AKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEA--KKAAEAKKKADEAKKAEE 1520

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 86562857   535 KNKRKMLEKEMEDRQNAIYEEEERRIAEEERRKQIEI---EERRRIQQqimiATEERSRLDAMEREREMLRQIKES 607
Cdd:PTZ00121 1521 AKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELkkaEEKKKAEE----AKKAEEDKNMALRKAEEAKKAEEA 1592

SMC_N

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

290-588

5.03e-11

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 66.92 E-value: 5.03e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    290 TENEFLNQLLHIVQHQKTVSERQQQEKFEKMEQERLRQEKEEKARELERRRKLEESETARQAELDRQATIYAEQERMAME 369
Cdd:pfam02463  710 EELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVE 789

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    370 RNRELERIRLEEKKRENERVRQEEIAMEISKIRELERLQLERQRKNERVRQELEAA---RKYKLQEEERQRKIQQQKVEM 446
Cdd:pfam02463  790 EEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEqklEKLAEEELERLEEEITKEELL 869

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    447 EQ--IRQQEEARQEQLRVLEEERARELERVRQEELERQHQMEILRQQEEDQKKKKLEKDREQREQQEAEELNRMIIEKEM 524
Cdd:pfam02463  870 QEllLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKE 949

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 86562857    525 KENKQKMIEEKNKRKMLEKEMEDR-----QNAIYEEEERRIAEEERRKQIEIEERRRIQQQIMIATEER 588
Cdd:pfam02463  950 KEENNKEEEEERNKRLLLAKEELGkvnlmAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQR 1018

PTZ00121

MAEBL; Provisional

303-621

7.63e-11

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 66.70 E-value: 7.63e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   303 QHQKTVSERQQQEKFEKMEQERLRQEKEEKARELERRRKLEES---------ETARQAELDRQ--------ATIYAEQER 365
Cdd:PTZ00121 1312 EEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAaadeaeaaeEKAEAAEKKKEeakkkadaAKKKAEEKK 1391

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   366 MAMERNRELERIRL---EEKKRENERVRQEEI---AMEISKIRELERlQLERQRKNERVRQELEAARKYK--LQEEERQR 437
Cdd:PTZ00121 1392 KADEAKKKAEEDKKkadELKKAAAAKKKADEAkkkAEEKKKADEAKK-KAEEAKKADEAKKKAEEAKKAEeaKKKAEEAK 1470

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   438 KIQQQKVEMEQIRQQEEAR---QEQLRVLEEERARELERVRQEEL---ERQHQMEILRQQEEDQKKKKLEKDREQREQQE 511
Cdd:PTZ00121 1471 KADEAKKKAEEAKKADEAKkkaEEAKKKADEAKKAAEAKKKADEAkkaEEAKKADEAKKAEEAKKADEAKKAEEKKKADE 1550

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   512 AEELNRMIIEKEMKENKQKMIEEKNKRKMLEKEMEDRQ----NAIYEEEERRIAEEERRKQIEIEERRRIQ-QQIMIATE 586
Cdd:PTZ00121 1551 LKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKaeeaRIEEVMKLYEEEKKMKAEEAKKAEEAKIKaEELKKAEE 1630

                         330       340       350
                  ....*....|....*....|....*....|....*
gi 86562857   587 ERSRLDAMEREREmlRQIKESEKQRKELERQELLA 621
Cdd:PTZ00121 1631 EKKKVEQLKKKEA--EEKKKAEELKKAEEENKIKA 1663

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

318-617

2.52e-10

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 64.70 E-value: 2.52e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    318 EKMEQ-ERLRQEKEEKARELERRRKLEESE-TARQAELDRQATIYAEQERMAMERNRELERI--RLEEKKRENERVRQ-- 391
Cdd:TIGR02169  195 EKRQQlERLRREREKAERYQALLKEKREYEgYELLKEKEALERQKEAIERQLASLEEELEKLteEISELEKRLEEIEQll 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    392 EEIAMEISKIRELERLQLerQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLRVLEEERAREL 471
Cdd:TIGR02169  275 EELNKKIKDLGEEEQLRV--KEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRR 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    472 ERVRQEELERQHQMEILRQQ-EEDQKKKKLEKDREQREQQEAEELNRMIieKEMKENKQKMIEEKNKRKMlekEMEDRQN 550
Cdd:TIGR02169  353 DKLTEEYAELKEELEDLRAElEEVDKEFAETRDELKDYREKLEKLKREI--NELKRELDRLQEELQRLSE---ELADLNA 427

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 86562857    551 AIyeeeerriaEEERRKQIEIEERRR-IQQQIMIATEERSRLDA-MEREREMLRQIKES----EKQRKELERQ 617
Cdd:TIGR02169  428 AI---------AGIEAKINELEEEKEdKALEIKKQEWKLEQLAAdLSKYEQELYDLKEEydrvEKELSKLQRE 491

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

318-616

3.85e-10

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 64.32 E-value: 3.85e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    318 EKMEQERLRQEKEEKARELERrrkLEESETARQAELDRQATIYAEQERMAMERNRELERIrleEKKRENERVRQEEIAME 397
Cdd:TIGR02169  672 EPAELQRLRERLEGLKRELSS---LQSELRRIENRLDELSQELSDASRKIGEIEKEIEQL---EQEEEKLKERLEELEED 745

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    398 ISKI-RELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEM--EQIRQQEEARQEQLRVLEEERARELERV 474
Cdd:TIGR02169  746 LSSLeQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEiqAELSKLEEEVSRIEARLREIEQKLNRLT 825

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    475 RQEELERQHQMEILRQQEEDQKKKKLEKDREQREQQEAEELNRMIIEKEMKENK--QKMIEEKNKRKMLEKEMEDRQNAI 552
Cdd:TIGR02169  826 LEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDleSRLGDLKKERDELEAQLRELERKI 905

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    553 yeeeerriaeEERRKQIEIEERR--RIQQQIMIATEERSRLD----AMEREREMLRQIKESEKQRKELER 616
Cdd:TIGR02169  906 ----------EELEAQIEKKRKRlsELKAKLEALEEELSEIEdpkgEDEEIPEEELSLEDVQAELQRVEE 965

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

336-614

6.87e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 63.15 E-value: 6.87e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    336 LERRRKLEESEtARQAELDRQATIyAEQERMAMERNRELERIRLEEKKRENERVRQEEIAMEISKIRELERLQLERQRkN 415
Cdd:TIGR02168  673 LERRREIEELE-EKIEELEEKIAE-LEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEER-I 749

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    416 ERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLRvleeeRARELERVRQEELERQHQMEILRQQEEDQ 495
Cdd:TIGR02168  750 AQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLK-----EELKALREALDELRAELTLLNEEAANLRE 824

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    496 KKKKLEKDREQreqqeaeelnrmiIEKEMKENKQKMIEEKNKRKMLEKEMEDRQNAIyeeeerriaeEERRKQIEIEERR 575
Cdd:TIGR02168  825 RLESLERRIAA-------------TERRLEDLEEQIEELSEDIESLAAEIEELEELI----------EELESELEALLNE 881

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 86562857    576 RIQQQIMIATEERSRLDAMEREREMLRQIKESEKQRKEL 614
Cdd:TIGR02168  882 RASLEEALALLRSELEELSEELRELESKRSELRRELEEL 920

TPH

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...

311-502

9.44e-10

Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 61.47 E-value: 9.44e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   311 RQQQEKFEKMEQERLRQEkEEKARELERRRKLEESETARQAELDRQATIYAEQERMAMERNRELERIrlEEKKRENERVR 390
Cdd:pfam13868 162 KEKAEREEEREAEREEIE-EEKEREIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEA--EKKARQRQELQ 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   391 QEEIAMEISKIRELER-LQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEME-QIRQQEEARQEQLRvleeera 468
Cdd:pfam13868 239 QAREEQIELKERRLAEeAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELEkQIEEREEQRAAERE------- 311

                         170       180       190
                  ....*....|....*....|....*....|....
gi 86562857   469 releRVRQEELERQHQMEILRQQEEDQKKKKLEK 502
Cdd:pfam13868 312 ----EELEEGERLREEEAERRERIEEERQKKLKE 341

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

324-618

1.43e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 62.26 E-value: 1.43e-09

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 324 RLRQEKEEKARELER-RRKLEESEtARQAELDRQATIYAEQERMAmERNRELerirleekkRENERVRQEEIAmeiskIR 402
Cdd:COG1196 169 KYKERKEEAERKLEAtEENLERLE-DILGELERQLEPLERQAEKA-ERYREL---------KEELKELEAELL-----LL 232

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 403 ELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLRvleeerareLERVRQEELERQ 482
Cdd:COG1196 233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEY---------ELLAELARLEQD 303

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 483 HQMEILRQQEedqkkkklekdreqreqqEAEELNRmiIEKEMKENKQKMIEEKNKRKMLEKEMEDRQNAIyeeeerriae 562
Cdd:COG1196 304 IARLEERRRE------------------LEERLEE--LEEELAELEEELEELEEELEELEEELEEAEEEL---------- 353

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 86562857 563 EERRKQIEIEERRRIQQQIMIATEERSRLDAMEREREMLRQIKESEKQRKELERQE 618
Cdd:COG1196 354 EEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAE 409

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

301-616

1.87e-09

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 62.00 E-value: 1.87e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    301 IVQHQKTVSERQQQEKFEKMEQERLRQEKEEKARELERRRKLEESETARQAELDRQ-ATIYAEQERMAMERNR-ELERIR 378
Cdd:TIGR02168  679 IEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDlARLEAEVEQLEERIAQlSKELTE 758

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    379 LEEKKRENERVRQEEIAMEISKIRELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQE 458
Cdd:TIGR02168  759 LEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATER 838

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    459 QLRVLEEERARElervrQEELER-QHQMEILRQQEEDQKK--KKLEKDREQREQQEAEELNRMII-EKEMKENKQKMIEE 534
Cdd:TIGR02168  839 RLEDLEEQIEEL-----SEDIESlAAEIEELEELIEELESelEALLNERASLEEALALLRSELEElSEELRELESKRSEL 913

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    535 KNKRKMLEKEMEDRQNaiyeeeerriaeeerrKQIEIE-ERRRIQQQIMiateERSRLDAMEREREMLRQIKESEKQRKE 613
Cdd:TIGR02168  914 RRELEELREKLAQLEL----------------RLEGLEvRIDNLQERLS----EEYSLTLEEAEALENKIEDDEEEARRR 973


                   ...
gi 86562857    614 LER 616
Cdd:TIGR02168  974 LKR 976

TPH

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...

326-619

3.30e-09

Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 59.55 E-value: 3.30e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   326 RQEKEEKARELERRRKleesETARQAELDRQATIYAEQERMAMERNRELERIRLEEKKRENERVRQEEIAMEISKIRELE 405
Cdd:pfam13868   1 LRENSDELRELNSKLL----AAKCNKERDAQIAEKKRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQ 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   406 RLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQ--QKVEMEQIRQQEEARQEQLRVLEEERARELERVRQEELERQH 483
Cdd:pfam13868  77 ELEEQIEEREQKRQEEYEEKLQEREQMDEIVERIQEedQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDER 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   484 QMEILRQQEEDQKKKKLEKdreqREQQEAEELNRMIIEKEMKENKQKM----------IEEKNKRKMLEKEMEDRQN--- 550
Cdd:pfam13868 157 ILEYLKEKAEREEEREAER----EEIEEEKEREIARLRAQQEKAQDEKaerdelraklYQEEQERKERQKEREEAEKkar 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   551 ---AIYEEEERRIAEEERRKQIEIEERRRIQQQIMIATEERSRLDAMERER----------EMLRQIKESEKQRKELERQ 617
Cdd:pfam13868 233 qrqELQQAREEQIELKERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKrrmkrlehrrELEKQIEEREEQRAAEREE 312


                  ..
gi 86562857   618 EL 619
Cdd:pfam13868 313 EL 314

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

303-610

8.77e-09

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 59.69 E-value: 8.77e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    303 QHQKTVSERQQQEKFEKMEQERLRQEKEEKARELERRRKLEESETARQAELDRQATIYAEQERMAMERNRELERiRLEEK 382
Cdd:TIGR02168  208 QAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEE-EIEEL 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    383 KRENERVRQE--EIAMEISKIRE-LERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQ 459
Cdd:TIGR02168  287 QKELYALANEisRLEQQKQILRErLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAE 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    460 LRVleeerARELERVRQEELERQHQMEILRQQEEDQKKKKLE---------KDREQREQQEAEELNRMIIEKEMKENKQK 530
Cdd:TIGR02168  367 LEE-----LESRLEELEEQLETLRSKVAQLELQIASLNNEIErlearlerlEDRRERLQQEIEELLKKLEEAELKELQAE 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    531 MIEEKNKRKMLEKEMEDRQNAIYEEEerriaeeerrkqieiEERRRIQQQIMIATEE----RSRLDAMEREREMLRQIKE 606
Cdd:TIGR02168  442 LEELEEELEELQEELERLEEALEELR---------------EELEEAEQALDAAERElaqlQARLDSLERLQENLEGFSE 506


                   ....
gi 86562857    607 SEKQ 610
Cdd:TIGR02168  507 GVKA 510

PTZ00121

MAEBL; Provisional

303-461

9.15e-09

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 59.77 E-value: 9.15e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   303 QHQKTVSERQQQEKFEKMEQERLRQEKEE-KARELERRRKLEE----SETARQAELDRQATiyAEQERMAMERNRELERI 377
Cdd:PTZ00121 1630 EEKKKVEQLKKKEAEEKKKAEELKKAEEEnKIKAAEEAKKAEEdkkkAEEAKKAEEDEKKA--AEALKKEAEEAKKAEEL 1707

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   378 R---LEEKKREnERVRQEEIAMEIsKIRELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEE 454
Cdd:PTZ00121 1708 KkkeAEEKKKA-EELKKAEEENKI-KAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEEL 1785


                  ....*..
gi 86562857   455 ARQEQLR 461
Cdd:PTZ00121 1786 DEEDEKR 1792

sbcc

TIGR00618

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

273-550

1.11e-08

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 59.21 E-value: 1.11e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    273 LTTMTPEYTVRYNGQTMTENEFLNQLLHIVQHQKTVSERQQQEKFEKMEQERLRQE------KEEKARELERRRKLEESE 346
Cdd:TIGR00618  206 LTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLlkqlraRIEELRAQEAVLEETQER 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    347 TARQAELDRQATIYAEQERMAMERNRELERIRLEEKKRENERVRQEEIAMEISKIRELERLQLERQRKNERVRQELEAAR 426
Cdd:TIGR00618  286 INRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVAT 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    427 KYK------LQEEERQRKIQQQKVEMEQIRQQEEARQEQLRvleeerarelervrqeelERQHQMEILRQQEEDQKKKKL 500
Cdd:TIGR00618  366 SIReiscqqHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQ------------------REQATIDTRTSAFRDLQGQLA 427

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|
gi 86562857    501 EKDREQREQQEAEELNRMIIEKEMKENKQKMIEEKNKRKMLEKEMEDRQN 550
Cdd:TIGR00618  428 HAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQT 477

PTZ00121

MAEBL; Provisional

338-622

1.99e-08

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 58.61 E-value: 1.99e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   338 RRRKLEESETARQAELDRQATIYAEQERMAMERNRELERIRLEEKKRENERVRQEEIAMEISKIRELERL-QLERQRKNE 416
Cdd:PTZ00121 1070 EGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDArKAEEARKAE 1149

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   417 RVRQELEAARKYKLQEEERQRKIQQQKvEMEQIRQQEEARQ-EQLRVLEEERARELERVRQEE--LERQHQMEILRQQEE 493
Cdd:PTZ00121 1150 DAKRVEIARKAEDARKAEEARKAEDAK-KAEAARKAEEVRKaEELRKAEDARKAEAARKAEEErkAEEARKAEDAKKAEA 1228

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   494 DQKKKKLEKDREQREQQEAEELNRMIIEKEMKE-----NKQKMIEEKNKRKMLE-KEMEDRQNAIYEEEERRIAEEERRK 567
Cdd:PTZ00121 1229 VKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARmahfaRRQAAIKAEEARKADElKKAEEKKKADEAKKAEEKKKADEAK 1308

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 86562857   568 QiEIEERRRIQQQIMIATEERSRLDAMEREREMLRQIKESEKQRKELERQELLAT 622
Cdd:PTZ00121 1309 K-KAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAA 1362

DUF4670

pfam15709

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...

311-457

3.83e-08

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.

Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 57.27 E-value: 3.83e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   311 RQQQEKFEKMEQ--ERLRQEKEEKARELERRRKLEESETARQAELDRQAtiyAEQERMAMERNR-----------ELERI 377
Cdd:pfam15709 362 RLQQEQLERAEKmrEELELEQQRRFEEIRLRKQRLEEERQRQEEEERKQ---RLQLQAAQERARqqqeefrrklqELQRK 438

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   378 RLEE--KKRENERVRQEEIAMEISK-------IRELERLQLERQRKNERVRQELEAarkyklqEEERQRKIQQQKVEMEQ 448
Cdd:pfam15709 439 KQQEeaERAEAEKQRQKELEMQLAEeqkrlmeMAEEERLEYQRQKQEAEEKARLEA-------EERRQKEEEAARLALEE 511

                         170
                  ....*....|.
gi 86562857   449 IRQQ--EEARQ 457
Cdd:pfam15709 512 AMKQaqEQARQ 522

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

345-622

4.03e-08

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 57.39 E-value: 4.03e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    345 SETARQAELDrQATIYAEQERMAmERNRELERIR--LEEKKRENERVRQEEIameiSKIRELERLQLERQRKNERVRQEL 422
Cdd:TIGR02169  659 SRAPRGGILF-SRSEPAELQRLR-ERLEGLKRELssLQSELRRIENRLDELS----QELSDASRKIGEIEKEIEQLEQEE 732

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    423 EAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLRvleeeRARELERVRQEELERQHQMEILRQ-QEEDQKKKKLE 501
Cdd:TIGR02169  733 EKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELE-----EDLHKLEEALNDLEARLSHSRIPEiQAELSKLEEEV 807

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    502 KDREQREQQEAEELNRM-----IIEKEMKENKQKMIEEKNKRKMLEKEMEDRQNAIyeeeerrIAEEERRKQIEIEERRR 576
Cdd:TIGR02169  808 SRIEARLREIEQKLNRLtlekeYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKK-------EELEEELEELEAALRDL 880

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 86562857    577 IQQQIMIAtEERSRLDAMEREREMLRQIKESEKQRKELERQELLAT 622
Cdd:TIGR02169  881 ESRLGDLK-KERDELEAQLRELERKIEELEAQIEKKRKRLSELKAK 925

ATAD3_N

pfam12037

ATPase family AAA domain-containing protein 3, N-terminal; This is the conserved N-terminal ...

333-533

4.23e-08

ATPase family AAA domain-containing protein 3, N-terminal; This is the conserved N-terminal domain of ATPase family AAA domain-containing protein 3 (ATAD3) which is involved in dimerization and interacts with the inner surface of the outer mitochondrial membrane. This domain is found associated with the AAA ATPase domain (pfam00004). ATAD3 is essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organizm and cellular level. It may also play an important role in mitochondrial protein synthesis.

Pssm-ID: 463442 [Multi-domain] Cd Length: 264 Bit Score: 55.37 E-value: 4.23e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   333 ARELERRRKLEES-ETARQAELDRQATIYAEQERM-AMERNRELERIRLEEKKRenervrqeeiameiskiRELerLQLE 410
Cdd:pfam12037  35 ARELESSPHAKKAlELMKKQEQTRQAELQAKIKEYeAAQEQLKIERQRVEYEER-----------------RKT--LQEE 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   411 RQRKNERVRQELEAARKYKLQEEERQRKIQQqkvemEQIRQQEE--ARQEQLRVleeerARELERVRQEELERQHQMEIL 488
Cdd:pfam12037  96 TKQKQQRAQYQDELARKRYQDQLEAQRRRNE-----ELLRKQEEsvAKQEAMRI-----QAQRRQTEEHEAELRRETERA 165

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 86562857   489 RQQEEDQKKKKLEKDREQREQqeaeelnRMIIEKeMKENKQKMIE 533
Cdd:pfam12037 166 KAEAEAEARAKEERENEDLNL-------EQLREK-ANEERETVLE 202

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

321-615

4.40e-08

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 57.37 E-value: 4.40e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    321 EQERLRQEKEE-KARELERRRKLEESETARQAELDRQATIYAEQERMAMERNRELERIRLEEKKRENERVRQEEIAMEIS 399
Cdd:TIGR02168  678 EIEELEEKIEElEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT 757

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    400 KIRELERLQLERQRKNERVRQELEAARkyklqeEERQRKIQQQKVEMEQIRQQ-EEARQEqlrVLEEERARELERVRQEE 478
Cdd:TIGR02168  758 ELEAEIEELEERLEEAEEELAEAEAEI------EELEAQIEQLKEELKALREAlDELRAE---LTLLNEEAANLRERLES 828

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    479 LERQHQMEILRQQEEDQKKKKLEKDREQreqqeaeelnrmiIEKEMKENKQKMIEEKNKRKMLEKEMEDRQNAIYEEEER 558
Cdd:TIGR02168  829 LERRIAATERRLEDLEEQIEELSEDIES-------------LAAEIEELEELIEELESELEALLNERASLEEALALLRSE 895

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    559 RIAEEERRKQIEiEERRRIQQQIMIATEERSRLDA-MEREREMLRQIKE--SEKQRKELE 615
Cdd:TIGR02168  896 LEELSEELRELE-SKRSELRRELEELREKLAQLELrLEGLEVRIDNLQErlSEEYSLTLE 954

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

291-621

4.87e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 57.25 E-value: 4.87e-08

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 291 ENEFLNQLLHIVQHQKTVSERQQQEKFEKMEQERLRQEKEEkaRELERRRKLEESETARQAELDRQATIYAEQERMAMER 370
Cdd:COG1196 385 AEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEE--LEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALL 462

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 371 NRELERIRLEEKKRENERVRQEEIAMEISKIRELERLQLERQRKNERVRQELEAARK-----------------YKLQEE 433
Cdd:COG1196 463 ELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLrglagavavligveaayEAALEA 542

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 434 ERQRKIQQQKVEMEQIRQQEEARQEQL---RVLEEERARELERVRQEELERQHQMEILRQQEEDQkkkkLEKDREQREQQ 510
Cdd:COG1196 543 ALAAALQNIVVEDDEVAAAAIEYLKAAkagRATFLPLDKIRARAALAAALARGAIGAAVDLVASD----LREADARYYVL 618

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 511 EAEELNRMIIEKEMKENKQKMIEEKNKRKMLEKEMEDRQNAiyeEEERRIAEEERRKQIEIEERRRIQQQIMIATEERSR 590
Cdd:COG1196 619 GDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAG---GSLTGGSRRELLAALLEAEAELEELAERLAEEELEL 695

                       330       340       350
                ....*....|....*....|....*....|.
gi 86562857 591 LDAMEREREMLRQIKESEKQRKELERQELLA 621
Cdd:COG1196 696 EEALLAEEEEERELAEAEEERLEEELEEEAL 726

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

381-629

7.50e-08

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 56.60 E-value: 7.50e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    381 EKKRENERVRQEeIAMEISKIRELERLQLERQRKNERVRQELEAARKyklQEEERQRKIQQQKVEMEQirqqEEARQEQL 460
Cdd:TIGR02168  674 ERRREIEELEEK-IEELEEKIAELEKALAELRKELEELEEELEQLRK---ELEELSRQISALRKDLAR----LEAEVEQL 745

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    461 RVLEEERARELERVRQEELERQHQMEILRQQEEDQKKKKLEKDREQREQQEAEELNRMIIEKEMKE----------NKQK 530
Cdd:TIGR02168  746 EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEltllneeaanLRER 825

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    531 MIEEKNKRKMLEKEMEDRQNAIYEEEERRIAEEERRKQIEiEERRRIQQQIMIATEERSRLD-----AMEREREMLRQIK 605
Cdd:TIGR02168  826 LESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE-ELIEELESELEALLNERASLEealalLRSELEELSEELR 904

                          250       260
                   ....*....|....*....|....
gi 86562857    606 ESEKQRKELERQELLATTPITTIK 629
Cdd:TIGR02168  905 ELESKRSELRRELEELREKLAQLE 928

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

303-617

8.69e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 56.31 E-value: 8.69e-08

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 303 QHQKTVSERQQQEKfekmEQERLRQEKEEKARELERRRKLEESETARQ--AELDRQATIYAEQERMAMERNRELERIRLE 380
Cdd:COG4717  89 EYAELQEELEELEE----ELEELEAELEELREELEKLEKLLQLLPLYQelEALEAELAELPERLEELEERLEELRELEEE 164

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 381 EKKRENERVR-QEEIAMEISKIRELERLQLERQRKN-ERVRQELEAARK--YKLQEEERQRKIQQQKVEMEQIRQQEEAR 456
Cdd:COG4717 165 LEELEAELAElQEELEELLEQLSLATEEELQDLAEElEELQQRLAELEEelEEAQEELEELEEELEQLENELEAAALEER 244

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 457 QEQLRV----------------------------------------LEEERARELERVRQEELERQHQMEILRQQEEDQK 496
Cdd:COG4717 245 LKEARLllliaaallallglggsllsliltiagvlflvlgllallfLLLAREKASLGKEAEELQALPALEELEEEELEEL 324

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 497 KKKLEKDREQREQQEAEELNRMIIEKEMKENKQKMIEEKnKRKMLEKEME---DRQNAIYEEEERRIAEEERRKQIEIEE 573
Cdd:COG4717 325 LAALGLPPDLSPEELLELLDRIEELQELLREAEELEEEL-QLEELEQEIAallAEAGVEDEEELRAALEQAEEYQELKEE 403

                       330       340       350       360
                ....*....|....*....|....*....|....*....|....
gi 86562857 574 RRRIQQQIMIATEERSRLDAMEREREMLRQIKESEKQRKELERQ 617
Cdd:COG4717 404 LEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEE 447

SMC_N

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

281-581

1.09e-07

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 56.13 E-value: 1.09e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    281 TVRYNGQTMTENEFLNQLLHIVQHQKTVSER---QQQEKFEKMEQERLRQEKEEKARELERRRKLEESETARQA--ELDR 355
Cdd:pfam02463  228 YLDYLKLNEERIDLLQELLRDEQEEIESSKQeieKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSEllKLER 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    356 QATIYAEQERMAMERNRELERIRLEEKKRENERVRQEEIAMEISKIRELERLQLERQRKNERVRQElEAARKYKLQEEER 435
Cdd:pfam02463  308 RKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEE-ELLAKKKLESERL 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    436 QRKIQQQKVEMEQIRQQEEARQEQLRVLEEERARELERVRQEELERQhqmEILRQQEEDQKKKKLEKDREQREQQEAEEL 515
Cdd:pfam02463  387 SSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILE---EEEESIELKQGKLTEEKEELEKQELKLLKD 463

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 86562857    516 NRMIIEKEMKENKQKMIEEKNKRKMLEKEMEDRQNAIYEEEERRIAEEERRKQIEIEERRRIQQQI 581
Cdd:pfam02463  464 ELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHG 529

PRK03918

DNA double-strand break repair ATPase Rad50;

297-617

1.97e-07

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 55.07 E-value: 1.97e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  297 QLLHIVQHQKTVSER-QQQEKFEKMEQERLRqEKEEKARELE----------RRRKLEESETARQAELDRQATIYAE--- 362
Cdd:PRK03918 246 ELESLEGSKRKLEEKiRELEERIEELKKEIE-ELEEKVKELKelkekaeeyiKLSEFYEEYLDELREIEKRLSRLEEein 324

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  363 --QERM--AMERNRELERIRLEEKKRENERVRQEEIAMEISKIRELERlQLERQRKN------ERVRQELEAARKYKLQE 432
Cdd:PRK03918 325 giEERIkeLEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKE-ELERLKKRltgltpEKLEKELEELEKAKEEI 403

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  433 EERQRKIQQQKVEMEQIRQQEEARQEQLRvleeeRARELERVRQEELERQHQMEILRQQEEDQKKkklekdreqreqqea 512
Cdd:PRK03918 404 EEEISKITARIGELKKEIKELKKAIEELK-----KAKGKCPVCGRELTEEHRKELLEEYTAELKR--------------- 463

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  513 eelnrmiIEKEMKENKQKMIEEKNKRKMLEKEM--EDRQNAIYEEEERRIAEEERRKQIEIEERRR-------------- 576
Cdd:PRK03918 464 -------IEKELKEIEEKERKLRKELRELEKVLkkESELIKLKELAEQLKELEEKLKKYNLEELEKkaeeyeklkeklik 536

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|..
gi 86562857  577 IQQQIMIATEERSRLDAMERE-REMLRQIKESEKQRKELERQ 617
Cdd:PRK03918 537 LKGEIKSLKKELEKLEELKKKlAELEKKLDELEEELAELLKE 578

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

303-494

2.32e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 54.00 E-value: 2.32e-07

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 303 QHQKTVSERQQQEKFEKMEQERLRQEKEEKARELERRRKLEESETARQAELDRQATIYAEQERMAMERNRELERIRLEEK 382
Cdd:COG4942  21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 383 KRENERVRQEEIAMEISKIRELERL-------QLER-----QRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIR 450
Cdd:COG4942 101 AQKEELAELLRALYRLGRQPPLALLlspedflDAVRrlqylKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....
gi 86562857 451 QQEEARQEQLRVLEEERARELERVRQEELERQHQMEILRQQEED 494
Cdd:COG4942 181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224

DUF4670

pfam15709

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...

344-617

2.38e-07

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.

Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 54.57 E-value: 2.38e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   344 ESETARQAELDRQATIYA-EQERMAMERNRELeriRLEEKKRENERVRQEEiameiskiRELERLQLERQRKNERVRQEL 422
Cdd:pfam15709 310 ESEEERSEEDPSKALLEKrEQEKASRDRLRAE---RAEMRRLEVERKRREQ--------EEQRRLQQEQLERAEKMREEL 378

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   423 EAARKyKLQEEERQRKiqqQKVEMEQIRQQEEARQEQLRvleeerareleRVRQEELERQHQMEILRQQEEDQKKKKlek 502
Cdd:pfam15709 379 ELEQQ-RRFEEIRLRK---QRLEEERQRQEEEERKQRLQ-----------LQAAQERARQQQEEFRRKLQELQRKKQ--- 440

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   503 dreqreqqeaeelnrmiiekemKENKQKMIEEKNKRKMLEKEMEDRQNAIYEEEErriaeeerrkqieiEERRRIQQQIM 582
Cdd:pfam15709 441 ----------------------QEEAERAEAEKQRQKELEMQLAEEQKRLMEMAE--------------EERLEYQRQKQ 484

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 86562857   583 IAtEERSRLDAMEREREMLRQIK----ESEKQRKELERQ 617
Cdd:pfam15709 485 EA-EEKARLEAEERRQKEEEAARlaleEAMKQAQEQARQ 522

TPH

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...

312-526

3.01e-07

Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 53.77 E-value: 3.01e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   312 QQQEKFEKMEQERLRQEKEEKARELER----RRKLEESETARQAELDRQATIYAEQERMAMERNRELERIRLEEKKRENE 387
Cdd:pfam13868 108 ERIQEEDQAEAEEKLEKQRQLREEIDEfneeQAEWKELEKEEEREEDERILEYLKEKAEREEEREAEREEIEEEKEREIA 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   388 RVRQEeIAMEISKIRELERLQLER---QRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLRVLE 464
Cdd:pfam13868 188 RLRAQ-QEKAQDEKAERDELRAKLyqeEQERKERQKEREEAEKKARQRQELQQAREEQIELKERRLAEEAEREEEEFERM 266

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 86562857   465 EERARELERVRQEELER------QHQMEILRQQEEDQKKKKLEK-------DREQREQQEAEELNRMIIEKEMKE 526
Cdd:pfam13868 267 LRKQAEDEEIEQEEAEKrrmkrlEHRRELEKQIEEREEQRAAEReeeleegERLREEEAERRERIEEERQKKLKE 341

Cep57_CLD

pfam14073

Centrosome localization domain of Cep57; The CLD or centrosome localization domain of Cep57 is ...

295-448

3.55e-07

Centrosome localization domain of Cep57; The CLD or centrosome localization domain of Cep57 is found at the N-terminus, and lies approximately between residues 58 and 239. This region lies within the first alpha-helical coiled-coil segment of Cep57, and localizes to the centrosome internally to gamma-tubulin, suggesting that it is either on both centrioles or on a centromatrix component. This N-terminal region can also multimerize with the N-terminus of other Cep57 molecules. The C-terminal part, Family Cep57_MT_bd, pfam06657, is the microtubule-binding region of Cep57.

Pssm-ID: 464080 [Multi-domain] Cd Length: 178 Bit Score: 51.47 E-value: 3.55e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   295 LNQLLHIVQHQKTVSERQQQEKF-EKMEQERLRQEKEEKARELERRRKLEEsetaRQAELDRQatiyaeqermaMERNRE 373
Cdd:pfam14073  27 LKQLSRETSHYKEVLQKENDARDpSRGEVSKQNQELISQLAAAESRCSLLE----KQLEYMRK-----------MVENAE 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   374 LERIRLEEKKRENERVRQEEIAMEISKIRELERLQLE------RQRKNERVRQELEAarkyKLQEEERQRKIQQQKVEME 447
Cdd:pfam14073  92 KERTAVLEKQASLERERSQDSSELQAQLEKLEKLEQEylrltrTQSLAETKIKELEE----KLQEEEHQRKLVQEKAAQL 167


                  .
gi 86562857   448 Q 448
Cdd:pfam14073 168 Q 168

tolA_full

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...

416-539

3.89e-07

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]

Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 53.31 E-value: 3.89e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   416 ERVRQELEAARKyklQEEERQRKIQQQKVEMEQIRQQEEARQEQL--RVLEEERARELERVRQEELERQHQMEILRQQEE 493
Cdd:TIGR02794  53 NRIQQQKKPAAK---KEQERQKKLEQQAEEAEKQRAAEQARQKELeqRAAAEKAAKQAEQAAKQAEEKQKQAEEAKAKQA 129

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 86562857   494 DQKKKKLEKDReqreqqeaeelnrmiiEKEMKENKQKMIEEKNKRK 539
Cdd:TIGR02794 130 AEAKAKAEAEA----------------ERKAKEEAAKQAEEEAKAK 159

PRK03918

DNA double-strand break repair ATPase Rad50;

310-619

4.81e-07

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 53.91 E-value: 4.81e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  310 ERQQQEKFEKME---QERLRQEKEEKARELERRRKLEESETARQAELDrqatiyaeqerMAMERNRELERIR--LEEKKR 384
Cdd:PRK03918 177 RIERLEKFIKRTeniEELIKEKEKELEEVLREINEISSELPELREELE-----------KLEKEVKELEELKeeIEELEK 245

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  385 ENERVRQEEIAMEIsKIRELE------RLQLERQRKNERVRQELE-AARKY-KLQEEERQRKIQQQKVEMEQIRQQEEAR 456
Cdd:PRK03918 246 ELESLEGSKRKLEE-KIRELEerieelKKEIEELEEKVKELKELKeKAEEYiKLSEFYEEYLDELREIEKRLSRLEEEIN 324

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  457 QEQLRVLEEERARELERVRQEELER-QHQMEILRQ-----QEEDQKKKKLEKDREQREQQEAEELNRMI---------IE 521
Cdd:PRK03918 325 GIEERIKELEEKEERLEELKKKLKElEKRLEELEErhelyEEAKAKKEELERLKKRLTGLTPEKLEKELeelekakeeIE 404

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  522 KEMKENKQKMIEEKNKRKMLEKEM-------------------EDRQNAIYEEEERRIAEEERRKQIEIEER--RRIQQQ 580
Cdd:PRK03918 405 EEISKITARIGELKKEIKELKKAIeelkkakgkcpvcgrelteEHRKELLEEYTAELKRIEKELKEIEEKERklRKELRE 484

                        330       340       350
                 ....*....|....*....|....*....|....*....
gi 86562857  581 IMIATEERSRLdamEREREMLRQIKESEKQRKELERQEL 619
Cdd:PRK03918 485 LEKVLKKESEL---IKLKELAEQLKELEEKLKKYNLEEL 520

YqiK

COG2268

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

305-461

6.10e-07

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

Pssm-ID: 441869 [Multi-domain] Cd Length: 439 Bit Score: 52.95 E-value: 6.10e-07

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 305 QKTVSERQQQEkfekmEQERLRQEkeekaRELERRRKLEEsetarQAELD-RQATIYAEQERmamernrelERIRLEEKK 383
Cdd:COG2268 213 EIAIAQANREA-----EEAELEQE-----REIETARIAEA-----EAELAkKKAEERREAET---------ARAEAEAAY 268

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 86562857 384 RENERVRQEEIAMEISKIRELERLQLERQRKnERVRQELEAARKyKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLR 461
Cdd:COG2268 269 EIAEANAEREVQRQLEIAEREREIELQEKEA-EREEAELEADVR-KPAEAEKQAAEAEAEAEAEAIRAKGLAEAEGKR 344

PTZ00266

NIMA-related protein kinase; Provisional

316-423

6.87e-07

NIMA-related protein kinase; Provisional

Pssm-ID: 173502 [Multi-domain] Cd Length: 1021 Bit Score: 53.59 E-value: 6.87e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   316 KFEKMEQERLRQEKEEKARE------LERRRkLEESETARQAELDRQATIYAEQERMAMERnreLERIRLEEKKRENERV 389
Cdd:PTZ00266  429 RVDKDHAERARIEKENAHRKalemkiLEKKR-IERLEREERERLERERMERIERERLERER---LERERLERDRLERDRL 504

                          90       100       110
                  ....*....|....*....|....*....|....
gi 86562857   390 RQeeiaMEISKIRELERLQLERQRKNERVRQELE 423
Cdd:PTZ00266  505 DR----LERERVDRLERDRLEKARRNSYFLKGME 534

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

295-494

7.10e-07

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 53.52 E-value: 7.10e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    295 LNQLLHIVQHQK--TVSERQQQEKFEKM---EQERLRQEKEEKARELERRRKLEESETARQAELDRQATIYAEQERMAME 369
Cdd:TIGR02168  293 LANEISRLEQQKqiLRERLANLERQLEEleaQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELES 372

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    370 RNRELERIRLEEKKRENERVRQEE-IAMEISKIR-ELERLQLERQRKNERVRQELEAARKYKLQE-----EERQRKIQQQ 442
Cdd:TIGR02168  373 RLEELEEQLETLRSKVAQLELQIAsLNNEIERLEaRLERLEDRRERLQQEIEELLKKLEEAELKElqaelEELEEELEEL 452

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 86562857    443 KVEMEQIRQQEEARQEQLRVLEEERARELE---RVRQeeleRQHQMEILRQQEED 494
Cdd:TIGR02168  453 QEELERLEEALEELREELEEAEQALDAAERelaQLQA----RLDSLERLQENLEG 503

PTZ00121

MAEBL; Provisional

303-443

8.22e-07

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 53.22 E-value: 8.22e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   303 QHQKTVSERQQQEKFEKMEQERLRQEKEEKaRELERRRKLEESETARqaeldrqatiyAEQERMAMERNreleRIRLEEK 382
Cdd:PTZ00121 1672 EDKKKAEEAKKAEEDEKKAAEALKKEAEEA-KKAEELKKKEAEEKKK-----------AEELKKAEEEN----KIKAEEA 1735

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 86562857   383 KR--ENERVRQEEIAMEISKIRELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQK 443
Cdd:PTZ00121 1736 KKeaEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDK 1798

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

321-499

8.68e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 52.85 E-value: 8.68e-07

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 321 EQERLRQEKEEKARELERRRKLEESETARQAELDRQATIYAE--QERMAMERNRELERIRLEEKKRENER----VRQEEI 394
Cdd:COG4717  72 ELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEElrEELEKLEKLLQLLPLYQELEALEAELaelpERLEEL 151

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 395 AMEISKIRELERLQLERQRKNERVRQELEAARKYKLQEEERQrkIQQQKVEMEQIRQQEEARQEQLRvleeerarelerV 474
Cdd:COG4717 152 EERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEE--LQDLAEELEELQQRLAELEEELE------------E 217

                       170       180
                ....*....|....*....|....*.
gi 86562857 475 RQEELER-QHQMEILRQQEEDQKKKK 499
Cdd:COG4717 218 AQEELEElEEELEQLENELEAAALEE 243

DUF4659

pfam15558

Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins ...

299-549

1.18e-06

Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins in this family are typically between 427 and 674 amino acids in length. There are two completely conserved residues (D and I) that may be functionally important.

Pssm-ID: 464768 [Multi-domain] Cd Length: 374 Bit Score: 51.96 E-value: 1.18e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   299 LHIVQHQKT--VSERQQQEKFEKMEQERLRQEKEEKArELERRRKLEESETARQAELD-RQATIYAEQERMA--MERNRE 373
Cdd:pfam15558  12 LMLARHKEEqrMRELQQQAALAWEELRRRDQKRQETL-ERERRLLLQQSQEQWQAEKEqRKARLGREERRRAdrREKQVI 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   374 LERIRLEEKKRENERVRQEEIAMEISKIRELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEME-QIRQQ 452
Cdd:pfam15558  91 EKESRWREQAEDQENQRQEKLERARQEAEQRKQCQEQRLKEKEEELQALREQNSLQLQERLEEACHKRQLKEREeQKKVQ 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   453 EEARQEQLRVLEeerarelervrqeeleRQHQMEILRQQEEDQKKKKLEKDREQREQQEAEELNRMiiEKEMKENKQKMI 532
Cdd:pfam15558 171 ENNLSELLNHQA----------------RKVLVDCQAKAEELLRRLSLEQSLQRSQENYEQLVEER--HRELREKAQKEE 232

                         250
                  ....*....|....*..
gi 86562857   533 EEKNKRKMLEKEMEDRQ 549
Cdd:pfam15558 233 EQFQRAKWRAEEKEEER 249

MAP7

pfam05672

MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is ...

311-436

1.19e-06

MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is presumably controlled by tissue-specific microtubule-associated proteins (MAPs). The 115-kDa epithelial MAP (E-MAP-115/MAP7) has been identified as a microtubule-stabilising protein predominantly expressed in cell lines of epithelial origin. The binding of this microtubule associated protein is nucleotide independent.

Pssm-ID: 461709 [Multi-domain] Cd Length: 153 Bit Score: 49.27 E-value: 1.19e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   311 RQQQEKFEKMEQERLRQEKEEKARELERRRKLEESETARQAELDRQatiyaEQERmameRNRELERIRLEEKKRENERVR 390
Cdd:pfam05672  21 RQAREQREREEQERLEKEEEERLRKEELRRRAEEERARREEEARRL-----EEER----RREEEERQRKAEEEAEEREQR 91

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 86562857   391 QEEIAMEISKIRELErlqlERQRKNERVRQELEAARKYKLQEEERQ 436
Cdd:pfam05672  92 EQEEQERLQKQKEEA----EAKAREEAERQRQEREKIMQQEEQERL 133

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

310-623

1.20e-06

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 52.76 E-value: 1.20e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    310 ERQQQEKFEKM-EQERLRQEKEEKARELERRRKLEESETARQAELDRQATiYAEQERMAMERNRELERIRLEEKKRENER 388
Cdd:TIGR02169  698 RRIENRLDELSqELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS-SLEQEIENVKSELKELEARIEELEEDLHK 776

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    389 VRQEEIAME-------ISKIRELERLQLERQRKNERVRQELEAARKYKLQEEER-QRKIQQQKVEMEQIRQQEEARQEQL 460
Cdd:TIGR02169  777 LEEALNDLEarlshsrIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYlEKEIQELQEQRIDLKEQIKSIEKEI 856

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    461 rvleeerarELERVRQEELERQHQMEILRQQEEDQKKKKLEKDreqreqqeaeelnRMIIEKEMKENKQKMIEEKNKRKM 540
Cdd:TIGR02169  857 ---------ENLNGKKEELEEELEELEAALRDLESRLGDLKKE-------------RDELEAQLRELERKIEELEAQIEK 914

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    541 LEKEMEDRQNAIYEEEERRIAEEERRKQIE------------IEERRRIQQQIMiATEERSRLDAMEREREMLRQIKESE 608
Cdd:TIGR02169  915 KRKRLSELKAKLEALEEELSEIEDPKGEDEeipeeelsledvQAELQRVEEEIR-ALEPVNMLAIQEYEEVLKRLDELKE 993

                          330
                   ....*....|....*.
gi 86562857    609 KQRK-ELERQELLATT 623
Cdd:TIGR02169  994 KRAKlEEERKAILERI 1009

Mitofilin

pfam09731

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ...

270-460

1.31e-06

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.

Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 52.45 E-value: 1.31e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   270 VEELTTMTPEYTVRYNGQTMTENEFLNQLlhiVQHQKTvserqqqeKFEKMEQERLRQEKEEKARelerrrkLEESETAR 349
Cdd:pfam09731 260 QQELVSIFPDIIPVLKEDNLLSNDDLNSL---IAHAHR--------EIDQLSKKLAELKKREEKH-------IERALEKQ 321

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   350 QAELDRQatiyaeqermamernRELERIRLEEKKRENERVRQEEIAMEISKIRE----LERLQLERQRK--NERVRQELe 423
Cdd:pfam09731 322 KEELDKL---------------AEELSARLEEVRAADEAQLRLEFEREREEIREsyeeKLRTELERQAEahEEHLKDVL- 385

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 86562857   424 aarkyKLQEEERQRKiQQQKVEmEQIRQQEEARQEQL 460
Cdd:pfam09731 386 -----VEQEIELQRE-FLQDIK-EKVEEERAGRLLKL 415

COG4372

Uncharacterized protein, contains DUF3084 domain [Function unknown];

311-612

2.05e-06

Uncharacterized protein, contains DUF3084 domain [Function unknown];

Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 51.06 E-value: 2.05e-06

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 311 RQQQEKFEKMEQE--RLRQEKEEKARELERRrkleesetarQAELDRQATIYAEQERMAMERNRELERIRLEEKKRENE- 387
Cdd:COG4372  34 RKALFELDKLQEEleQLREELEQAREELEQL----------EEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEEl 103

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 388 -RVRQEEIAMEiskiRELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLRVLEEE 466
Cdd:COG4372 104 eSLQEEAEELQ----EELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEA 179

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 467 RARELERVRQEELERQHQMEILRQQEEDQKKKKLEKDREQREQQEAEELNRMIIEKEMKENKQKMIEEKNKRKMLEKEME 546
Cdd:COG4372 180 EAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKE 259

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 86562857 547 DRQNAIYEEEERRIAEEERRKQIEIEERRRIQQQIMIATEERSRLDAMEREREMLRQIKESEKQRK 612
Cdd:COG4372 260 IEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELA 325

tolA_full

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...

315-498

2.73e-06

Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 50.61 E-value: 2.73e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   315 EKFEKMEQERLRQEKEEKARELERRRKLEESETARQAELDRQATIYAEQERMAMERNRElerirlEEKKRENERVRQEEI 394
Cdd:TIGR02794  50 QQANRIQQQKKPAAKKEQERQKKLEQQAEEAEKQRAAEQARQKELEQRAAAEKAAKQAE------QAAKQAEEKQKQAEE 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   395 AMEISKIRELERLQLERQRK-NERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLRVLEEERARELER 473
Cdd:TIGR02794 124 AKAKQAAEAKAKAEAEAERKaKEEAAKQAEEEAKAKAAAEAKKKAEEAKKKAEAEAKAKAEAEAKAKAEEAKAKAEAAKA 203

                         170       180
                  ....*....|....*....|....*
gi 86562857   474 VRQEELERQHQMEILRQQEEDQKKK 498
Cdd:TIGR02794 204 KAAAEAAAKAEAEAAAAAAAEAERK 228

sbcc

TIGR00618

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

295-605

2.77e-06

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 51.51 E-value: 2.77e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    295 LNQLLHIVQHqktvsERQQQEKFEKMEQERLRQEKEEKARELERRRKLEESETARQAELDRQATIYAEQERMAMERNREL 374
Cdd:TIGR00618  589 LQNITVRLQD-----LTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREH 663

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    375 ERIRLEEKKRENERVRQEEIAMEiSKIRELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQirqQEE 454
Cdd:TIGR00618  664 ALSIRVLPKELLASRQLALQKMQ-SEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAA---RED 739

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    455 ARQEqlrvleeerarelervRQEELERQhQMEILRQQEEDQKKKKLEKDREQREQQEAEELNRMIIEK---------EMK 525
Cdd:TIGR00618  740 ALNQ----------------SLKELMHQ-ARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFnrlreedthLLK 802

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    526 ENKQKmIEEKNKRKMLEKEMEDRQNAIYEEEERRIAEEERRKQIEI-------EERRRIQQQimiATEERSRLDAMERER 598
Cdd:TIGR00618  803 TLEAE-IGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEIthqllkyEECSKQLAQ---LTQEQAKIIQLSDKL 878


                   ....*..
gi 86562857    599 EMLRQIK 605
Cdd:TIGR00618  879 NGINQIK 885

SCP-1

pfam05483

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...

311-537

2.78e-06

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.

Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 51.26 E-value: 2.78e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   311 RQQQEKFEKMEQER--LRQEKEEKARELERRRKLEESetaRQAELDRQATIYAEQERMaMERNRELERIRLEEKKRENE- 387
Cdd:pfam05483 366 RTEQQRLEKNEDQLkiITMELQKKSSELEEMTKFKNN---KEVELEELKKILAEDEKL-LDEKKQFEKIAEELKGKEQEl 441

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   388 ----RVRQEEI---AMEISKIRELERL------QLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEE 454
Cdd:pfam05483 442 ifllQAREKEIhdlEIQLTAIKTSEEHylkeveDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQED 521

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   455 ----ARQEQLRVLEEERARELERVRQEELERQHQMEILRQQEEDQKKKKLEKDREQREQQEAEELNRMIIEKEMKENKQK 530
Cdd:pfam05483 522 iincKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKK 601


                  ....*..
gi 86562857   531 MIEEKNK 537
Cdd:pfam05483 602 QIENKNK 608

MFAP1

pfam06991

Microfibril-associated/Pre-mRNA processing; MFAP1 was first named for proteins associated with ...

309-437

2.94e-06

Microfibril-associated/Pre-mRNA processing; MFAP1 was first named for proteins associated with microfibrils which are an important component of the extracellular matrix (ECM) of many tissues. For example, MFAP1 has been shown to be associated with elastin-like fibres at the base of Schlemm's canal endothelium cells, in the juxtacanalicular tissue, and in the uveal region. Based on its role in the ECM and the proximity of the MFAP1 gene to FBN1 it was hypothesized that mutations in MFAP1 contributed to heritable diseases affecting microfibrils, Marfan syndrome but this has now been shown not to be the case. MFAP1 has also been shown to interact directly with certain pre-mRNA processing factor proteins, Prps, which are also spliceosome components and is thus required for pre-mRNA processing. MAFP1 bound to Pr38 of yeast is necessary for cells in vivo to progress from G2 to M phase.

Pssm-ID: 462060 [Multi-domain] Cd Length: 215 Bit Score: 49.09 E-value: 2.94e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   309 SERQQQEKFEKMEQERLRQEKEEKARELERRrklEESETARQAELDRQAtiyaeQERMAMERNRELERIrlEEKKRENEr 388
Cdd:pfam06991  20 SKRGTIAEREKLEAEEEEEEEEAKKEAEERK---KEADKLVEEEIRREA-----AAKEAGDEDENEEDV--DDTDGLDP- 88

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 86562857   389 vrqeEIAMEISKIRELERLQLERQRKNERVRQELEAARKYKLQEEERQR 437
Cdd:pfam06991  89 ----EAEYEAWKLRELKRIKRDREEREAREKEREEIERRRNMTEEERLA 133

SMC_N

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

305-547

3.13e-06

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 51.51 E-value: 3.13e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    305 QKTVSERQQQEKFEKMEQERLRQEKEEKARELERRRKLEESETARQAELdrqatiyaeqermamernrELERIRLEEKKR 384
Cdd:pfam02463  804 RALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLA-------------------EEELERLEEEIT 864

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    385 ENERVRQEEIAMEISKIRELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLRVLE 464
Cdd:pfam02463  865 KEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEE 944

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    465 EERARELERVRQEELERQHQMEilRQQEEDQKKKKLEKDREQREQQEAEELNRMIIEKEMKENKQKMIEEKNKRKMLEKE 544
Cdd:pfam02463  945 ADEKEKEENNKEEEEERNKRLL--LAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEF 1022


                   ...
gi 86562857    545 MED 547
Cdd:pfam02463 1023 LEL 1025

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

323-543

3.58e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 51.09 E-value: 3.58e-06

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 323 ERLRQEKEEKAREL----ERRRKLEESETARQAELDRQATIYAEQERMAMERNRELERIRLEekkreneRVRQEEIAMEI 398
Cdd:COG1196 564 EYLKAAKAGRATFLpldkIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGR-------TLVAARLEAAL 636

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 399 SKIRELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLRVLEEERARELERVRQEE 478
Cdd:COG1196 637 RRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEER 716

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 86562857 479 LERQHQMEILRQQEEDQKKKKLEKDREQREQQEAEELNRMIIEKEMKENKQKMIEEKNKRKMLEK 543
Cdd:COG1196 717 LEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGP 781

TPH

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...

401-621

4.25e-06

Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 49.92 E-value: 4.25e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   401 IRELERLQLERQRKNERVRQELEAARKYKLQEEER------QRKIQQQKVEMEQIRQQEEARQEQLRvleeerarelerv 474
Cdd:pfam13868  28 IAEKKRIKAEEKEEERRLDEMMEEERERALEEEEEkeeerkEERKRYRQELEEQIEEREQKRQEEYE------------- 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   475 rQEELERQHQMEILRQ-QEEDQKKKKLEKDREQREQQEAEELNRMIIE-KEMKENKQKMIEEKNKRKMLEKEMEDRQNAi 552
Cdd:pfam13868  95 -EKLQEREQMDEIVERiQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEwKELEKEEEREEDERILEYLKEKAEREEERE- 172

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 86562857   553 yeeeeRRIAEEERRKQIEIEERRRIQQQIMIATEERSRLDAMEREREMLRQIKESEKQRKELERQELLA 621
Cdd:pfam13868 173 -----AEREEIEEEKEREIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQE 236

PRK12704

phosphodiesterase; Provisional

319-458

7.10e-06

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 49.78 E-value: 7.10e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  319 KMEQERLRQEKEEKARE--LERRRKLEESETARQAELDRqatiyaeQERMAMERNRELERiRLEEKKRENERVRQEEIAM 396
Cdd:PRK12704  48 KKEAEAIKKEALLEAKEeiHKLRNEFEKELRERRNELQK-------LEKRLLQKEENLDR-KLELLEKREEELEKKEKEL 119

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 86562857  397 EiSKIRELERLQLERQRKNERVRQELEAARKYKlQEEERQRKIQQQKVEMEQ-----IRQ-QEEARQE 458
Cdd:PRK12704 120 E-QKQQELEKKEEELEELIEEQLQELERISGLT-AEEAKEILLEKVEEEARHeaavlIKEiEEEAKEE 185

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

287-444

7.75e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 49.77 E-value: 7.75e-06

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 287 QTMTENEFLNQLLHIVQHQKTVSERQQQEKFEKMEQERLRQEKEEKARELERRRKLEESETARQAELDRQATIYAEQERM 366
Cdd:COG4717 351 ELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEEL 430

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 367 AMERNRELERIRLEEKKRENERVRQEEIAMEISKI---RELERLQLERQRKNERVRQELEAARKYKLQE---EERQRKIQ 440
Cdd:COG4717 431 EEELEELEEELEELEEELEELREELAELEAELEQLeedGELAELLQELEELKAELRELAEEWAALKLALellEEAREEYR 510


                ....
gi 86562857 441 QQKV 444
Cdd:COG4717 511 EERL 514

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

295-462

7.93e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 49.91 E-value: 7.93e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  295 LNQLLHIVQHQKTVseRQQQEKFEKMEQERLRQEKEEKARELERRRKLEESETARQAELDRQATIyAEQERMAMERnrel 374
Cdd:COG4913  251 IELLEPIRELAERY--AAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELER-LEARLDALRE---- 323

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  375 ERIRLEEKKRENERVRQEEIAmeiskiRELERLQLERQRKNERVRQELEAARKYKLQE-------EERQRKIQQQKVEME 447
Cdd:COG4913  324 ELDELEAQIRGNGGDRLEQLE------REIERLERELEERERRRARLEALLAALGLPLpasaeefAALRAEAAALLEALE 397

                        170
                 ....*....|....*
gi 86562857  448 QIRQQEEARQEQLRV 462
Cdd:COG4913  398 EELEALEEALAEAEA 412

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

318-498

9.27e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 49.38 E-value: 9.27e-06

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 318 EKMEQERLRQEKEEKARELERRRKLEESETARQAELDRQATIYAEQERMAmERNRELERIRLEEKKRENERVRQEEIAME 397
Cdd:COG4717  49 ERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELE-ELEEELEELEAELEELREELEKLEKLLQL 127

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 398 ISKIRELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLRVLEEERARELERVRQE 477
Cdd:COG4717 128 LPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQR 207

                       170       180
                ....*....|....*....|.
gi 86562857 478 ELERQHQMEILRQQEEDQKKK 498
Cdd:COG4717 208 LAELEEELEEAQEELEELEEE 228

tolA_full

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...

406-539

1.22e-05

Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 48.69 E-value: 1.22e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   406 RLQLERQRKNERVR-----QELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLRVLEEERARELERVR----- 475
Cdd:TIGR02794  56 QQQKKPAAKKEQERqkkleQQAEEAEKQRAAEQARQKELEQRAAAEKAAKQAEQAAKQAEEKQKQAEEAKAKQAAeakak 135

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 86562857   476 -QEELERQHQMEILRQQEEDQKKKKLEKDREQREQQEAEelnRMIIEKEMKENKQKMIEEKNKRK 539
Cdd:TIGR02794 136 aEAEAERKAKEEAAKQAEEEAKAKAAAEAKKKAEEAKKK---AEAEAKAKAEAEAKAKAEEAKAK 197

Myosin_tail_1

pfam01576

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...

311-552

1.25e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.

Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 49.40 E-value: 1.25e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    311 RQQQEKFEKMEQERLRQEKEEKA----RELERR-RKLEESETARQAELDRQATIYAEQERMamernreleRIRLEEKKRE 385
Cdd:pfam01576    2 RQEEEMQAKEEELQKVKERQQKAeselKELEKKhQQLCEEKNALQEQLQAETELCAEAEEM---------RARLAARKQE 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    386 NERVRQEeiaMEISKIRELER---LQLERQRKNERVrQELEAarkyKLQEEERQRkiqqQKVEMEQIRQQEEARQEQLRV 462
Cdd:pfam01576   73 LEEILHE---LESRLEEEEERsqqLQNEKKKMQQHI-QDLEE----QLDEEEAAR----QKLQLEKVTTEAKIKKLEEDI 140

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    463 LEEERARELERVRQEELERQHQMEILRQQEEDQKKKKLEKDREQREQQEAEELNRMiiekeMKENKQKMIEEKNKRKmLE 542
Cdd:pfam01576  141 LLLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERL-----KKEEKGRQELEKAKRK-LE 214

                          250
                   ....*....|
gi 86562857    543 KEMEDRQNAI 552
Cdd:pfam01576  215 GESTDLQEQI 224

tolA

cell envelope integrity inner membrane protein TolA; Provisional

303-437

1.28e-05

cell envelope integrity inner membrane protein TolA; Provisional

Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 48.65 E-value: 1.28e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  303 QHQKTVSERQQQEKFEKMEQERLRQEKEEKARELERRRKLEESETARQaELDRQAtiyAEQERMAMERNRELErirlEEK 382
Cdd:PRK09510  67 QQQQQKSAKRAEEQRKKKEQQQAEELQQKQAAEQERLKQLEKERLAAQ-EQKKQA---EEAAKQAALKQKQAE----EAA 138

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 86562857  383 KRENERVR-----QEEIAMEISKIRELE---RLQLERQRKNE-RVRQELEAARKYKLQEEERQR 437
Cdd:PRK09510 139 AKAAAAAKakaeaEAKRAAAAAKKAAAEakkKAEAEAAKKAAaEAKKKAEAEAAAKAAAEAKKK 202

sbcc

TIGR00618

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

295-619

1.41e-05

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 49.20 E-value: 1.41e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    295 LNQLLHIVQHQKTVSErqQQEKFEKMEQERLRQEKEEKARELERRRKL-------EESETARQAELDRQATIYAEQERMA 367
Cdd:TIGR00618  377 LTQHIHTLQQQKTTLT--QKLQSLCKELDILQREQATIDTRTSAFRDLqgqlahaKKQQELQQRYAELCAAAITCTAQCE 454

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    368 MERNRELERIRLEEKKRENERVRQEEIAMEISKIRELERLQLERQRKNERV----RQELEAARKYKLQEEERQRKIQQQK 443
Cdd:TIGR00618  455 KLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPlcgsCIHPNPARQDIDNPGPLTRRMQRGE 534

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    444 VEMEQIRQQEEARQEQLrvleEERARELERVRQEELERQHQMEILRQQ----EEDQKKKKLEKDREQREQQEAEELNRMI 519
Cdd:TIGR00618  535 QTYAQLETSEEDVYHQL----TSERKQRASLKEQMQEIQQSFSILTQCdnrsKEDIPNLQNITVRLQDLTEKLSEAEDML 610

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    520 IEKEMKENKQKMIEEKNKRKMLEKEMEDRQNAIYEEEERRIAEEERRKQIEIEERRRIQQQIMIATEERSRLDAMERERE 599
Cdd:TIGR00618  611 ACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKE 690

                          330       340
                   ....*....|....*....|
gi 86562857    600 MLRQIKESEKQRKELERQEL 619
Cdd:TIGR00618  691 QLTYWKEMLAQCQTLLRELE 710

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

305-498

1.46e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 49.00 E-value: 1.46e-05

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 305 QKTVSERQQQEKFEKMEQERLRQEkeEKARELERRRKLEESETARQAELDRQATIYAEQERMAMERNRELERIRLEEKKR 384
Cdd:COG4717 296 EKASLGKEAEELQALPALEELEEE--ELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIA 373

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 385 ENERVRQ----EEIAMEISKIRELERLQLERQRKNERVRQELEAARKY--KLQEEERQRKIQQQKVEMEQIRQQEEARQE 458
Cdd:COG4717 374 ALLAEAGvedeEELRAALEQAEEYQELKEELEELEEQLEELLGELEELleALDEEELEEELEELEEELEELEEELEELRE 453

                       170       180       190       200
                ....*....|....*....|....*....|....*....|
gi 86562857 459 QLRvleeerareLERVRQEELERQHQMEILRQQEEDQKKK 498
Cdd:COG4717 454 ELA---------ELEAELEQLEEDGELAELLQELEELKAE 484

Caldesmon

pfam02029

Caldesmon;

302-601

1.52e-05

Caldesmon;

Pssm-ID: 460421 [Multi-domain] Cd Length: 495 Bit Score: 48.71 E-value: 1.52e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   302 VQHQKTVSERQQQEKFEKMEQERLRQEKEEKARELERRRKLEESETARQAELDRQAT-----IYAEQERMAMERNRELER 376
Cdd:pfam02029  38 PNEHNSYEEDSELKPSGQGGLDEEEAFLDRTAKREERRQKRLQEALERQKEFDPTIAdekesVAERKENNEEEENSSWEK 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   377 irleEKKRENERVRQEEIAMEIS-------KIRELERLQLERQRKNERVRQELEAARKYKLQEEE----RQRKIQQQKVE 445
Cdd:pfam02029 118 ----EEKRDSRLGRYKEEETEIRekeyqenKWSTEVRQAEEEGEEEEDKSEEAEEVPTENFAKEEvkdeKIKKEKKVKYE 193

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   446 MEQIRQQEEARQEQlrvLEEERARELERVRQEELERQHQMEILRQQEEDQKK-----KKLEKDREQREQQEaeelnrmii 520
Cdd:pfam02029 194 SKVFLDQKRGHPEV---KSQNGEEEVTKLKVTTKRRQGGLSQSQEREEEAEVfleaeQKLEELRRRRQEKE--------- 261

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   521 EKEMKENKQKMIEEKNKRKMLEKEMEDRQNAIYEEEERRIAEEERRKQIEIEERRRIQQQImiateERSRLDAMEREREM 600
Cdd:pfam02029 262 SEEFEKLRQKQQEAELELEELKKKREERRKLLEEEEQRRKQEEAERKLREEEEKRRMKEEI-----ERRRAEAAEKRQKL 336


                  .
gi 86562857   601 L 601
Cdd:pfam02029 337 P 337

PRK03918

DNA double-strand break repair ATPase Rad50;

315-629

1.77e-05

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 48.91 E-value: 1.77e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  315 EKFEKMEQERLRQEKEEKA--------RELERRRKLEESETARQAELDrqatiyaeqermamERNRELERiRLEEKKREN 386
Cdd:PRK03918 145 ESREKVVRQILGLDDYENAyknlgeviKEIKRRIERLEKFIKRTENIE--------------ELIKEKEK-ELEEVLREI 209

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  387 ERVRQEEIameiSKIRELERLQlERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLRvleee 466
Cdd:PRK03918 210 NEISSELP----ELREELEKLE-KEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELE----- 279

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  467 RARELERVRQEELERQHQMEILRQQEEDqKKKKLEKdREQREQQEAEELNRMIIEKEMKENKQKMIEEKnkrkmlEKEME 546
Cdd:PRK03918 280 EKVKELKELKEKAEEYIKLSEFYEEYLD-ELREIEK-RLSRLEEEINGIEERIKELEEKEERLEELKKK------LKELE 351

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  547 DRQNaiyeeeerriaeeerrkqiEIEERRRIQQQIMIATEERSRLDAMERER---EMLRQIKESEKQRKELERQELLATT 623
Cdd:PRK03918 352 KRLE-------------------ELEERHELYEEAKAKKEELERLKKRLTGLtpeKLEKELEELEKAKEEIEEEISKITA 412


                 ....*.
gi 86562857  624 PITTIK 629
Cdd:PRK03918 413 RIGELK 418

MAP7

pfam05672

MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is ...

379-501

1.95e-05

Pssm-ID: 461709 [Multi-domain] Cd Length: 153 Bit Score: 45.80 E-value: 1.95e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   379 LEEKKR--ENERVRQEEIAMEISKIRELERLQLERQRKNERVRQELEAAR---KYKLQEEERQRKIQQQKVEMEQIRQQE 453
Cdd:pfam05672  16 LAEKRRqaREQREREEQERLEKEEEERLRKEELRRRAEEERARREEEARRleeERRREEEERQRKAEEEAEEREQREQEE 95

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 86562857   454 EARQEQLRVLEEERARELERVRQEELERQHQMEilrQQEEDQKKKKLE 501
Cdd:pfam05672  96 QERLQKQKEEAEAKAREEAERQRQEREKIMQQE---EQERLERKKRIE 140

YqiK

COG2268

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

372-503

2.07e-05

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

Pssm-ID: 441869 [Multi-domain] Cd Length: 439 Bit Score: 47.95 E-value: 2.07e-05

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 372 RELERIRLEEKKRENERVRQEEIAMEiSKIRELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQ 451
Cdd:COG2268 192 RKIAEIIRDARIAEAEAERETEIAIA-QANREAEEAELEQEREIETARIAEAEAELAKKKAEERREAETARAEAEAAYEI 270

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|..
gi 86562857 452 QEEARQEQLRVLEeerarelervrqEELERQHQMEiLRQQEEDQKKKKLEKD 503
Cdd:COG2268 271 AEANAEREVQRQL------------EIAEREREIE-LQEKEAEREEAELEAD 309

TolA

COG3064

Membrane protein TolA involved in colicin uptake [Cell wall/membrane/envelope biogenesis];

305-593

2.69e-05

Membrane protein TolA involved in colicin uptake [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442298 [Multi-domain] Cd Length: 485 Bit Score: 47.73 E-value: 2.69e-05

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 305 QKTVSERQQQEKFEKMEQER-LRQEKEEKARELERRRKLEESETARQAE----------LDRQATIYAEQERMAMERNR- 372
Cdd:COG3064   6 EEKAAEAAAQERLEQAEAEKrAAAEAEQKAKEEAEEERLAELEAKRQAEeeareakaeaEQRAAELAAEAAKKLAEAEKa 85

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 373 --ELERIRLEEKKRENERVRQEEIAMEISKIRELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIR 450
Cdd:COG3064  86 aaEAEKKAAAEKAKAAKEAEAAAAAEKAAAAAEKEKAEEAKRKAEEEAKRKAEEERKAAEAEAAAKAEAEAARAAAAAAA 165

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 451 QQEEARQEQLRVLEEERARELERVRQEELERQHQMEILRQQEEDQKKKKLEKDREQREQQEAEELNRMIIEKEMKENKQK 530
Cdd:COG3064 166 AAAAAAARAAAGAAAALVAAAAAAVEAADTAAAAAAALAAAAAAAAADAALLALAVAARAAAASREAALAAVEATEEAAL 245

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 86562857 531 MIEEKNKRKMLEKEMEDRQNAIYEEEERRIAEEERRKQIEIEERRRIQQQIMIATEERSRLDA 593
Cdd:COG3064 246 GGAEEAADLAAVGVLGAALAAAAAGAAALSSGLVVVAAALAGLAAAAAGLVLDDSAALAAELL 308

growth_prot_Scy

NF041483

polarized growth protein Scy;

307-461

2.78e-05

polarized growth protein Scy;

Pssm-ID: 469371 [Multi-domain] Cd Length: 1293 Bit Score: 48.28 E-value: 2.78e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   307 TVSERQQQEKFEKM--EQERLRQEKEEKAREL---------ERRRKLEESETARQAELDRQAT----------------- 358
Cdd:NF041483  516 TTLRRQAEETLERTraEAERLRAEAEEQAEEVraaaeraarELREETERAIAARQAEAAEELTrlhteaeerltaaeeal 595

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   359 --IYAEQERMAMERNRELERIRLEEKKR----------ENERVRqEEIAMEISKIR----------------ELERLQLE 410
Cdd:NF041483  596 adARAEAERIRREAAEETERLRTEAAERirtlqaqaeqEAERLR-TEAAADASAARaegenvavrlrseaaaEAERLKSE 674

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   411 RQRKNERVRQEL---------EAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLR 461
Cdd:NF041483  675 AQESADRVRAEAaaaaervgtEAAEALAAAQEEAARRRREAEETLGSARAEADQERERAR 734

PRK02224

DNA double-strand break repair Rad50 ATPase;

301-458

2.83e-05

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 48.11 E-value: 2.83e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  301 IVQHQKTVSERQQQekfekmeQERLRQEKEEKARELERRRklEESETAR-QAELDRQATIYAEQERMAMERNRE-LERIR 378
Cdd:PRK02224 525 IAERRETIEEKRER-------AEELRERAAELEAEAEEKR--EAAAEAEeEAEEAREEVAELNSKLAELKERIEsLERIR 595

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  379 LEEKKRENERVRQEEIAMEISKIRELERLQLER-QRKNERVRQ---ELEAARKYKLQEEERQRKIQQQKVEmEQIRQQEE 454
Cdd:PRK02224 596 TLLAAIADAEDEIERLREKREALAELNDERRERlAEKRERKREleaEFDEARIEEAREDKERAEEYLEQVE-EKLDELRE 674


                 ....
gi 86562857  455 ARQE 458
Cdd:PRK02224 675 ERDD 678

DUF4659

pfam15558

Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins ...

303-462

3.09e-05

Pssm-ID: 464768 [Multi-domain] Cd Length: 374 Bit Score: 47.34 E-value: 3.09e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   303 QHQKTVSERQQQEKFEKMEQERLRQEKEEKARELERRRK------LEESETARQAELDRQatIYAEQERMAM-ERNRELE 375
Cdd:pfam15558  84 RREKQVIEKESRWREQAEDQENQRQEKLERARQEAEQRKqcqeqrLKEKEEELQALREQN--SLQLQERLEEaCHKRQLK 161

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   376 RIRLEEKKRENER-------VRQEEIAMEISKIRELERLQLE-RQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEmE 447
Cdd:pfam15558 162 EREEQKKVQENNLsellnhqARKVLVDCQAKAEELLRRLSLEqSLQRSQENYEQLVEERHRELREKAQKEEEQFQRAK-W 240

                         170
                  ....*....|....*
gi 86562857   448 QIRQQEEARQEQLRV 462
Cdd:pfam15558 241 RAEEKEEERQEHKEA 255

tolA

cell envelope integrity inner membrane protein TolA; Provisional

378-498

3.10e-05

cell envelope integrity inner membrane protein TolA; Provisional

Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 47.49 E-value: 3.10e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  378 RLEEKKRENERVRQEEIAMEISKIRELERLQLERQRKNERVRQELEAARKYKLQEEERQRKI--QQQKVEMEQIRQQEEA 455
Cdd:PRK09510  66 RQQQQQKSAKRAEEQRKKKEQQQAEELQQKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQAalKQKQAEEAAAKAAAAA 145

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 86562857  456 R----QEQLRVleeeraRELERVRQEELERQHQMEILRQQEEDQKKK 498
Cdd:PRK09510 146 KakaeAEAKRA------AAAAKKAAAEAKKKAEAEAAKKAAAEAKKK 186

hsdR

PRK11448

type I restriction enzyme EcoKI subunit R; Provisional

309-442

3.24e-05

type I restriction enzyme EcoKI subunit R; Provisional

Pssm-ID: 236912 [Multi-domain] Cd Length: 1123 Bit Score: 48.02 E-value: 3.24e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   309 SERQQQEKFEKMEQERLRQEKEEKARELERRRKLEESETARQAELDRQATIYaeqermamernrelerirlEEKkrener 388
Cdd:PRK11448  138 EDPENLLHALQQEVLTLKQQLELQAREKAQSQALAEAQQQELVALEGLAAEL-------------------EEK------ 192

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 86562857   389 vrQEEIAMEISKIRElERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQ 442
Cdd:PRK11448  193 --QQELEAQLEQLQE-KAAETSQERKQKRKEITDQAAKRLELSEEETRILIDQQ 243

Caldesmon

pfam02029

Caldesmon;

310-618

3.26e-05

Caldesmon;

Pssm-ID: 460421 [Multi-domain] Cd Length: 495 Bit Score: 47.55 E-value: 3.26e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   310 ERQQQEKFEKMEQERLRQEKEEKARELERRRklEESETARQAELDRQATIY----AEQERMAMERNRELERIRLEEKKRE 385
Cdd:pfam02029   5 EEAARERRRRAREERRRQKEEEEPSGQVTES--VEPNEHNSYEEDSELKPSgqggLDEEEAFLDRTAKREERRQKRLQEA 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   386 NERVRQ-EEIAMEISKIRELERLQLERQRKNERVRQELEAARKYKLQEEE---RQRKIQQQKVEMEQIRQQEEARQEQLR 461
Cdd:pfam02029  83 LERQKEfDPTIADEKESVAERKENNEEEENSSWEKEEKRDSRLGRYKEEEteiREKEYQENKWSTEVRQAEEEGEEEEDK 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   462 VLEEERARELERVRQEELERQHQMEILRQQE----EDQKKKKLEKDREQREQQEAEELNRMIIEKEMKENKQKMIEEKNK 537
Cdd:pfam02029 163 SEEAEEVPTENFAKEEVKDEKIKKEKKVKYEskvfLDQKRGHPEVKSQNGEEEVTKLKVTTKRRQGGLSQSQEREEEAEV 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   538 RKMLEKEMED--RQNAiyeeeerriaeeerrkQIEIEERRRIQQQIMIATEErsrLDAMEREREMLRQIKESEKQRKELE 615
Cdd:pfam02029 243 FLEAEQKLEElrRRRQ----------------EKESEEFEKLRQKQQEAELE---LEELKKKREERRKLLEEEEQRRKQE 303


                  ...
gi 86562857   616 RQE 618
Cdd:pfam02029 304 EAE 306

MAD

pfam05557

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...

348-628

3.85e-05

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.

Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 47.43 E-value: 3.85e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   348 ARQAELDRQaTIYAEQERMAMERNRELERIRLEEKKRENERVRQEEIAMEISKIRELERLQLERQRKNERVRQELEAARK 427
Cdd:pfam05557   2 AELIESKAR-LSQLQNEKKQMELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   428 YKLQEEERQRKIQQQKVEMEQIRQ-----QEEARQEQLRVLEEERARELERVRQEELERQHQMEILRQQEEDQKKKKLEK 502
Cdd:pfam05557  81 KKKYLEALNKKLNEKESQLADAREvisclKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEK 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   503 DREQREQQeaeelnrmiiEKEMKENKQKmIEEKNKRKMLEKEMEDRQNAIYEEEERRIAEEErrkqiEIEERRRIQQQIM 582
Cdd:pfam05557 161 QQSSLAEA----------EQRIKELEFE-IQSQEQDSEIVKNSKSELARIPELEKELERLRE-----HNKHLNENIENKL 224

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 86562857   583 IATEE----RSRLDAMEREREMLRQIK-ESEKQRKELERQELLATTPITTI 628
Cdd:pfam05557 225 LLKEEvedlKRKLEREEKYREEAATLElEKEKLEQELQSWVKLAQDTGLNL 275

tolA_full

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...

323-551

4.73e-05

Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 46.76 E-value: 4.73e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   323 ERLRQEKEEKARElERRRKLEESETARQAELDRQAtiyaEQERMAmernreleriRLEEKKRENERVRQEEIAmeiskir 402
Cdd:TIGR02794  53 NRIQQQKKPAAKK-EQERQKKLEQQAEEAEKQRAA----EQARQK----------ELEQRAAAEKAAKQAEQA------- 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   403 elerlqleRQRKNERVRQELEAARKyklQEEERQRKIQQ---QKVEMEQIRQQEEARQEQlrvleeerarelervRQEEL 479
Cdd:TIGR02794 111 --------AKQAEEKQKQAEEAKAK---QAAEAKAKAEAeaeRKAKEEAAKQAEEEAKAK---------------AAAEA 164

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 86562857   480 ERQhQMEILRQQEEDQKKKKLEKDREQREQQEaeelnrmiieKEMKENKQKMIEEKNKRKMLEKEMEDRQNA 551
Cdd:TIGR02794 165 KKK-AEEAKKKAEAEAKAKAEAEAKAKAEEAK----------AKAEAAKAKAAAEAAAKAEAEAAAAAAAEA 225

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

369-622

4.88e-05

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 47.36 E-value: 4.88e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    369 ERNRELERiRLEEKKRENERVrqEEIAMEISkiRELERLQLERQRKNE--RVRQELEAARKYKL-----QEEERQRKIQQ 441
Cdd:TIGR02168  172 ERRKETER-KLERTRENLDRL--EDILNELE--RQLKSLERQAEKAERykELKAELRELELALLvlrleELREELEELQE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    442 QKVEMEQIRQQEEARQ-------EQLRVLEEERARELERVRQEELERQHQMEILRQQEE--DQKKKKLEKDREQREQQEA 512
Cdd:TIGR02168  247 ELKEAEEELEELTAELqeleeklEELRLEVSELEEEIEELQKELYALANEISRLEQQKQilRERLANLERQLEELEAQLE 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    513 EELNRMIIEKEMKENKQKMIEEKNKRKMLEKEMEDRQNAIYEEEERRIAEEERRKQIEIEERRRIQQQIMIATEERSRLD 592
Cdd:TIGR02168  327 ELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLE 406

                          250       260       270
                   ....*....|....*....|....*....|....*
gi 86562857    593 A----MEREREMLRQIKES-EKQRKELERQELLAT 622
Cdd:TIGR02168  407 ArlerLEDRRERLQQEIEElLKKLEEAELKELQAE 441

PRK02224

DNA double-strand break repair Rad50 ATPase;

317-613

5.54e-05

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 47.34 E-value: 5.54e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  317 FEKMEQERLRQEKEE-KARELERRRKLEESETARQAeLDRQATIYAEQERMAMERNREL--ERIRLE------EKKRENE 387
Cdd:PRK02224 304 LDDADAEAVEARREElEDRDEELRDRLEECRVAAQA-HNEEAESLREDADDLEERAEELreEAAELEseleeaREAVEDR 382

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  388 RVRQEEIAMEISKIRE---------------LERLQLERQRKNERVRqELEAARKyklQEEERQRKIQQ----------- 441
Cdd:PRK02224 383 REEIEELEEEIEELRErfgdapvdlgnaedfLEELREERDELREREA-ELEATLR---TARERVEEAEAlleagkcpecg 458

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  442 QKVEMEQIRQQEEARQEqlRVLEEERARELERVRQEELERQHqmeilrqqEEDQKKKKLEKDREQREQQEAEELNRMIIE 521
Cdd:PRK02224 459 QPVEGSPHVETIEEDRE--RVEELEAELEDLEEEVEEVEERL--------ERAEDLVEAEDRIERLEERREDLEELIAER 528

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  522 KEMKENKQKMIEEKNKRKM-LEKEMEDRQNAIYEEEERRIAEEERRKQIE---------IEERRRIQQQIMIATEERSRL 591
Cdd:PRK02224 529 RETIEEKRERAEELRERAAeLEAEAEEKREAAAEAEEEAEEAREEVAELNsklaelkerIESLERIRTLLAAIADAEDEI 608

                        330       340
                 ....*....|....*....|..
gi 86562857  592 damEREREMLRQIKESEKQRKE 613
Cdd:PRK02224 609 ---ERLREKREALAELNDERRE 627

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

378-584

5.58e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 47.07 E-value: 5.58e-05

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 378 RLEEKKRENERVRQEEIAMEISKIRELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQ 457
Cdd:COG4717  50 RLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLP 129

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 458 EQLRVLEEERARELERVRQEELERQhqMEILRQQEEDQKKKKLEKDREQREQQEAEELNRMIIEKEMKENKQKMIEEKNK 537
Cdd:COG4717 130 LYQELEALEAELAELPERLEELEER--LEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQR 207

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*..
gi 86562857 538 RKMLEKEMEDRQNAIYEEEERRIAEEERRKQIEIEERRRIQQQIMIA 584
Cdd:COG4717 208 LAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLI 254

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

293-494

5.59e-05

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 47.36 E-value: 5.59e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    293 EFLNQLLHIVQHQKTVSERQQQEKFEKMEQERLRQEK-----EEKARELERRRKLEESE-TARQAELDRQATIYAEQE-- 364
Cdd:TIGR02168  746 EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAeieelEAQIEQLKEELKALREAlDELRAELTLLNEEAANLRer 825

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    365 RMAMERNRELERIRLE--EKKRENERVRQEEIAMEISKIRE-LERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQ 441
Cdd:TIGR02168  826 LESLERRIAATERRLEdlEEQIEELSEDIESLAAEIEELEElIEELESELEALLNERASLEEALALLRSELEELSEELRE 905

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 86562857    442 QKVEMEQIRQQEEARQEQLrvleeerARELERVRQEELERQHQMEILRQQEED 494
Cdd:TIGR02168  906 LESKRSELRRELEELREKL-------AQLELRLEGLEVRIDNLQERLSEEYSL 951

tolA

cell envelope integrity inner membrane protein TolA; Provisional

324-498

6.96e-05

cell envelope integrity inner membrane protein TolA; Provisional

Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 46.34 E-value: 6.96e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  324 RLRQEKEEKARELERRRKLEEsetaRQAELDRQATIyAEQERMamernRELERIRLEEKKrenERVRQEEIAmeiskire 403
Cdd:PRK09510  66 RQQQQQKSAKRAEEQRKKKEQ----QQAEELQQKQA-AEQERL-----KQLEKERLAAQE---QKKQAEEAA-------- 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  404 leRLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEME-QIRQQEEARQEQLRVLEEERARELERVRQEELERQ 482
Cdd:PRK09510 125 --KQAALKQKQAEEAAAKAAAAAKAKAEAEAKRAAAAAKKAAAEaKKKAEAEAAKKAAAEAKKKAEAEAAAKAAAEAKKK 202

                        170
                 ....*....|....*.
gi 86562857  483 HQMEILRQQEEDQKKK 498
Cdd:PRK09510 203 AEAEAKKKAAAEAKKK 218

Myosin_tail_1

pfam01576

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...

322-603

7.17e-05

Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 46.71 E-value: 7.17e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    322 QERLRQEKEEKARELERRRKLEESETARQAELDRQATIYAEQERMAMERNRELERIR--LEEKKRENERVRQEEIAMEIS 399
Cdd:pfam01576  277 QEDLESERAARNKAEKQRRDLGEELEALKTELEDTLDTTAAQQELRSKREQEVTELKkaLEEETRSHEAQLQEMRQKHTQ 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    400 KIRELERlQLERQRKN----ERVRQELEAARKyKLQEEerQRKIQQQKVEMEQIRQQEEARQEQLRVLEEERARELERVR 475
Cdd:pfam01576  357 ALEELTE-QLEQAKRNkanlEKAKQALESENA-ELQAE--LRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELA 432

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    476 QEELERQHQMEILRQ--QEEDQKKKKLEKDREQREQQEAEELNRMIIEKEMKEN-----KQKMIEEKNKRKMLEKEMEDR 548
Cdd:pfam01576  433 EKLSKLQSELESVSSllNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNlstrlRQLEDERNSLQEQLEEEEEAK 512

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 86562857    549 QNAIYEEEERRIAEEERRKQIE--------IEE-RRRIQQQIMIAT----EERSRLDAMEREREMLRQ 603
Cdd:pfam01576  513 RNVERQLSTLQAQLSDMKKKLEedagtleaLEEgKKRLQRELEALTqqleEKAAAYDKLEKTKNRLQQ 580

Casc1_N

pfam15927

Cancer susceptibility candidate 1 N-terminus; This presumed domain is functionally ...

315-386

8.08e-05

Cancer susceptibility candidate 1 N-terminus; This presumed domain is functionally uncharacterized. This domain family is found in eukaryotes, and is approximately 200 amino acids in length. The family is found in association with pfam12366. There are two completely conserved residues (N and W) that may be functionally important.

Pssm-ID: 464947 [Multi-domain] Cd Length: 201 Bit Score: 44.66 E-value: 8.08e-05

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 86562857   315 EKFEKMEQERLRQEKEEKAReLERRRKLEESETARQAELDRQATIYAEQERMAMERNRELERIRLEEKKREN 386
Cdd:pfam15927   1 ARLREEEEERLRAEEEEAER-LEEERREEEEEERLAAEQDRRAEELEELKHLLEERKEALEKLRAEAREEAE 71

DUF4659

pfam15558

Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins ...

378-621

8.96e-05

Pssm-ID: 464768 [Multi-domain] Cd Length: 374 Bit Score: 45.80 E-value: 8.96e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   378 RLEEKKRENERVRQEEIAMEISKIR-ELERLQLERQRK------NERVRQELEAaRKYKLQEEERQRKIQQQKvemeQIR 450
Cdd:pfam15558  16 RHKEEQRMRELQQQAALAWEELRRRdQKRQETLERERRlllqqsQEQWQAEKEQ-RKARLGREERRRADRREK----QVI 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   451 QQEEARQEQLRVLEEERARELERVRQEELER-QHQMEILRQQEEDQKKKKLEKDREQREQQEAEELNRMIieKEMKEnkQ 529
Cdd:pfam15558  91 EKESRWREQAEDQENQRQEKLERARQEAEQRkQCQEQRLKEKEEELQALREQNSLQLQERLEEACHKRQL--KEREE--Q 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   530 KMIEEKNKRKMLEKEMEDRQNAiyeeeeRRIAEEERRKQIEIEER----RRIQQQIMIATEERSRLDAMeREREMLRQIK 605
Cdd:pfam15558 167 KKVQENNLSELLNHQARKVLVD------CQAKAEELLRRLSLEQSlqrsQENYEQLVEERHRELREKAQ-KEEEQFQRAK 239

                         250
                  ....*....|....*...
gi 86562857   606 E--SEKQRKELERQELLA 621
Cdd:pfam15558 240 WraEEKEEERQEHKEALA 257

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

321-552

1.11e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.53 E-value: 1.11e-04

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 321 EQERLRQEKEEKARELERRRKLEESETARQAELDRQatiYAEQERMAMERNRELERIrleEKKRENERVRQEEIAMEISK 400
Cdd:COG4942  21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQ---LAALERRIAALARRIRAL---EQELAALEAELAELEKEIAE 94

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 401 IRElerlQLERQRKN--ERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLRVLEEERARELERVRQEE 478
Cdd:COG4942  95 LRA----ELEAQKEElaELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 86562857 479 LERQHQMEILRQQEEDQKKKKLEKDREQREQQEaeelnrmiIEKEMKENKQKMIEEKNKRKMLEKEMEDRQNAI 552
Cdd:COG4942 171 AERAELEALLAELEEERAALEALKAERQKLLAR--------LEKELAELAAELAELQQEAEELEALIARLEAEA 236

TolA

COG3064

Membrane protein TolA involved in colicin uptake [Cell wall/membrane/envelope biogenesis];

313-685

1.31e-04

Membrane protein TolA involved in colicin uptake [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442298 [Multi-domain] Cd Length: 485 Bit Score: 45.80 E-value: 1.31e-04

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 313 QQEKFEKMEQERLRQEKEEKARELERRRKLEESETARQAELDRQATIYAEQErmAMErnrELERIRLEEKKRENErvRQE 392
Cdd:COG3064   1 AQEALEEKAAEAAAQERLEQAEAEKRAAAEAEQKAKEEAEEERLAELEAKRQ--AEE---EAREAKAEAEQRAAE--LAA 73

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 393 EIAMEISKI-RELERLQLERQRKNERVRQELEAARKY-KLQEEERQRKIQQQKVEMEQ--IRQQEEARQEQLRVLEEERA 468
Cdd:COG3064  74 EAAKKLAEAeKAAAEAEKKAAAEKAKAAKEAEAAAAAeKAAAAAEKEKAEEAKRKAEEeaKRKAEEERKAAEAEAAAKAE 153

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 469 RELERVRQEELERQHQMEILRQQEEDQKKKKLEKDREQREQQEAEELNRMIIEKEMKENKQKMIEEKNKRKMLEKEMEDR 548
Cdd:COG3064 154 AEAARAAAAAAAAAAAAAARAAAGAAAALVAAAAAAVEAADTAAAAAAALAAAAAAAAADAALLALAVAARAAAASREAA 233

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 549 QNAIYEEEERRIAEEERRKQIEIEERRRIQQQIMIATEERSRLDAMEREREMLRQIKEsEKQRKELERQELLATTPITTI 628
Cdd:COG3064 234 LAAVEATEEAALGGAEEAADLAAVGVLGAALAAAAAGAAALSSGLVVVAAALAGLAAA-AAGLVLDDSAALAAELLGAVA 312

                       330       340       350       360       370
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 86562857 629 KPIYRPDISEYRPPDVESHMIRFTTQSPEWATPSPTWNPAWNTVTAEEETPGIPIIH 685
Cdd:COG3064 313 AEEAVLAAAAAAGALVVRGGGAASLEAALSLLAAGAAAAAAGAGALATGALGDALAA 369

tolA_full

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...

305-461

1.43e-04

Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 45.22 E-value: 1.43e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   305 QKTVSERQQQEKFEKMEQERLRQEKEEKARELERRRKleesETARQAELDRQATIYAEQERMAMERNR----ELERIRLE 380
Cdd:TIGR02794  71 KKLEQQAEEAEKQRAAEQARQKELEQRAAAEKAAKQA----EQAAKQAEEKQKQAEEAKAKQAAEAKAkaeaEAERKAKE 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   381 EKKRENERVRQEEIAMEISKIRELERLQLERQRKnervrQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQL 460
Cdd:TIGR02794 147 EAAKQAEEEAKAKAAAEAKKKAEEAKKKAEAEAK-----AKAEAEAKAKAEEAKAKAEAAKAKAAAEAAAKAEAEAAAAA 221


                  .
gi 86562857   461 R 461
Cdd:TIGR02794 222 A 222

PRK12704

phosphodiesterase; Provisional

424-623

1.48e-04

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 45.54 E-value: 1.48e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  424 AARKYKLQEEERQRKIQQQKVEMEQIRQQE--EARQEQLRvleeERARELERVRQEELERQHQMEILRQQEE--DQKKKK 499
Cdd:PRK12704  29 AEAKIKEAEEEAKRILEEAKKEAEAIKKEAllEAKEEIHK----LRNEFEKELRERRNELQKLEKRLLQKEEnlDRKLEL 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  500 LEKDREQREQQEAEELNRMIIEKEMKENKQKMIEEKNKRkmLEKEMedrqnaiyeeeerriaeeerrkQIEIEERRriqQ 579
Cdd:PRK12704 105 LEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQE--LERIS----------------------GLTAEEAK---E 157

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 86562857  580 QIMIATEERSRLDAMererEMLRQIKESEKQRKELERQELLATT 623
Cdd:PRK12704 158 ILLEKVEEEARHEAA----VLIKEIEEEAKEEADKKAKEILAQA 197

GumC

COG3206

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

384-635

1.54e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 45.78 E-value: 1.54e-04

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 384 RENERVRQEEIAMEISKIRElerlQLERQRKN-ERVRQELEA-ARKYKL--------QEEERQRKIQQQKVEMEQIRQQE 453
Cdd:COG3206 163 EQNLELRREEARKALEFLEE----QLPELRKElEEAEAALEEfRQKNGLvdlseeakLLLQQLSELESQLAEARAELAEA 238

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 454 EARQEQLRVLEEERARELERVRQEELERQhqmeiLRQQEEDQKKKKLEkdreqreqqeaeelnrmiIEKEMKENKQKMIE 533
Cdd:COG3206 239 EARLAALRAQLGSGPDALPELLQSPVIQQ-----LRAQLAELEAELAE------------------LSARYTPNHPDVIA 295

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 534 EKNKRKMLEKEMEDRQNAIYEEEERRIAEEERRKQIEIEERRRIQQQIMIATEERSRLDAMEREREMLRQIKES-EKQRK 612
Cdd:COG3206 296 LRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESlLQRLE 375

                       250       260
                ....*....|....*....|...
gi 86562857 613 ELERQELLATTPITTIKPIYRPD 635
Cdd:COG3206 376 EARLAEALTVGNVRVIDPAVVPL 398

CAF-1_p150

pfam11600

Chromatin assembly factor 1 complex p150 subunit, N-terminal; CAF-1_p150 is a polypeptide ...

361-457

1.60e-04

Chromatin assembly factor 1 complex p150 subunit, N-terminal; CAF-1_p150 is a polypeptide subunit of CAF-1, which functions in depositing newly synthesized and acetylated histones H3/H4 into chromatin during DNA replication and repair. CAF-1_p150 includes the HP1 interaction site, the PEST, KER and ED interacting sites. CAF-1_p150 interacts directly with newly synthesized and acetylated histones through the acidic KER and ED domains. The PEST domain is associated with proteins that undergo rapid proteolysis.

Pssm-ID: 402959 [Multi-domain] Cd Length: 164 Bit Score: 43.14 E-value: 1.60e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   361 AEQERMAMERNRELERIR--LEEKKRENERVRQEEIAM------EISKIRELERLQLERQRKNERVRQELEAARKYKLQE 432
Cdd:pfam11600  11 EEKEKQRLEKDKERLRRQlkLEAEKEEKERLKEEAKAEkerakeEARRKKEEEKELKEKERREKKEKDEKEKAEKLRLKE 90

                          90       100
                  ....*....|....*....|....*
gi 86562857   433 EERQRKIQQQKVEMEQIRQQEEARQ 457
Cdd:pfam11600  91 EKRKEKQEALEAKLEEKRKKEEEKR 115

COG4372

Uncharacterized protein, contains DUF3084 domain [Function unknown];

361-623

1.67e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];

Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 44.89 E-value: 1.67e-04

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 361 AEQERMAMERNRELERiRLEEKKRENERVRQEEIAMEiskiRELERLQLERQRKNERVRQ---ELEAARKYKLQEEERQR 437
Cdd:COG4372  30 SEQLRKALFELDKLQE-ELEQLREELEQAREELEQLE----EELEQARSELEQLEEELEElneQLQAAQAELAQAQEELE 104

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 438 KIQQQKVEMEQIRQQEEARQEQLRVLEEERARELERVRQEELERQHQMEILRQQEEdQKKKKLEKDREQREQQEAEELNR 517
Cdd:COG4372 105 SLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLE-SLQEELAALEQELQALSEAEAEQ 183

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 518 MIIEKEMKENKQKMIEEKNKRKMLEKEMEDRQNAIYEEEERRIAEEERRKQIEIEERRRIQQQIMIATEERSRLDAMERE 597
Cdd:COG4372 184 ALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEEL 263

                       250       260
                ....*....|....*....|....*.
gi 86562857 598 REMLRQIKESEKQRKELERQELLATT 623
Cdd:COG4372 264 ELAILVEKDTEEEELEIAALELEALE 289

PRK12704

phosphodiesterase; Provisional

303-415

2.13e-04

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 45.15 E-value: 2.13e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  303 QHQKTVSER----QQQEKFEKMEQERLRQEKEEKARELERRRKLEESETARQAELDRQAtiyAEQERMAMERNRELERI- 377
Cdd:PRK12704  72 EFEKELRERrnelQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKE---EELEELIEEQLQELERIs 148

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 86562857  378 ---RLEEKKRENERVRQE---EIAMEISKIRELERLQLERQRKN 415
Cdd:PRK12704 149 gltAEEAKEILLEKVEEEarhEAAVLIKEIEEEAKEEADKKAKE 192

GBP_C

pfam02841

Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral ...

305-392

2.20e-04

Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral guanylate-binding protein (GBP) is induced by interferon-gamma during macrophage induction. This family contains GBP1 and GPB2, both GTPases capable of binding GTP, GDP and GMP.

Pssm-ID: 460721 [Multi-domain] Cd Length: 297 Bit Score: 44.20 E-value: 2.20e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   305 QKTVSERQQQEKFEKMEQERLRQEKEEKARELE-RRRKLEESETARQAELDR-QATIYAEQERMAMERNRELERIRLEEK 382
Cdd:pfam02841 203 EKAIEAERAKAEAAEAEQELLREKQKEEEQMMEaQERSYQEHVKQLIEKMEAeREQLLAEQERMLEHKLQEQEELLKEGF 282

                          90
                  ....*....|
gi 86562857   383 KRENERVRQE 392
Cdd:pfam02841 283 KTEAESLQKE 292

Borrelia_P83

pfam05262

Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.

323-459

2.32e-04

Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.

Pssm-ID: 114011 [Multi-domain] Cd Length: 489 Bit Score: 44.99 E-value: 2.32e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   323 ERLRQEKE---EKARELERRRKLEESETARQA-----ELDRQATIYAEQERMA--MERNRELERIRLEEKKRENERV--- 389
Cdd:pfam05262 184 EALREDNEkgvNFRRDMTDLKERESQEDAKRAqqlkeELDKKQIDADKAQQKAdfAQDNADKQRDEVRQKQQEAKNLpkp 263

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 86562857   390 -----RQEEIAMEISKIRELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQ 459
Cdd:pfam05262 264 adtssPKEDKQVAENQKREIEKAQIEIKKNDEEALKAKDHKAFDLKQESKASEKEAEDKELEAQKKREPVAEDLQ 338

Mplasa_alph_rch

TIGR04523

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...

285-623

2.61e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.

Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 45.01 E-value: 2.61e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   285 NGQTMTENEFLNQLLHIVQHQKTVSERQQQEKFEKMEQERLRQEKEEkarelERRRKLEESETARQAELDRQATIYAEQE 364
Cdd:TIGR04523 260 DEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQ-----DWNKELKSELKNQEKKLEEIQNQISQNN 334

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   365 RMAMERNRELERIRLEEKKRENERV-RQEEIAmeiSKIRELERLQLERQRKNervrQELEaarKYKLQEEERQRKIQQQK 443
Cdd:TIGR04523 335 KIISQLNEQISQLKKELTNSESENSeKQRELE---EKQNEIEKLKKENQSYK----QEIK---NLESQINDLESKIQNQE 404

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   444 VEMEQIRQQEEARQEQLRVLEEERARELERVRQ-------------------EELER-----QHQMEILR------QQEE 493
Cdd:TIGR04523 405 KLNQQKDEQIKKLQQEKELLEKEIERLKETIIKnnseikdltnqdsvkeliiKNLDNtreslETQLKVLSrsinkiKQNL 484

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   494 DQKKKKLEKDREQREQQEAEELNrmiIEKEMKENKQKMIEEKNKRKMLEKEMEDRQNAIYEEEERRIAEEERRKQIEIE- 572
Cdd:TIGR04523 485 EQKQKELKSKEKELKKLNEEKKE---LEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEk 561

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|...
gi 86562857   573 ERRRIQQQIMIATEERSRLDAMEREREMLRQIKESEKQ--RKELERQELLATT 623
Cdd:TIGR04523 562 EIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKdlIKEIEEKEKKISS 614

tape_meas_lam_C

TIGR01541

phage tail tape measure protein, lambda family; This model represents a relatively ...

348-455

2.63e-04

phage tail tape measure protein, lambda family; This model represents a relatively well-conserved region near the C-terminus of the tape measure protein of a lambda and related phage. This protein, which controls phage tail length, is typically about 1000 residues in length. Both low-complexity sequence and insertion/deletion events appear common in this family. Mutational studies suggest a ruler or template role in the determination of phage tail length. Similar behavior is attributed to proteins from distantly related or unrelated families in other phage. [Mobile and extrachromosomal element functions, Prophage functions]

Pssm-ID: 273681 [Multi-domain] Cd Length: 332 Bit Score: 44.44 E-value: 2.63e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   348 ARQAELDRQATIYAEQERMAMERNRELERIRLEEKKRENERVRQEEIAMEISKIRELERLQLERQ--------RKNERVR 419
Cdd:TIGR01541   7 TQQIADRKLKKLNTADEKSLQSRSDEIIALIKLEKLLEEAEQKALEALKKLAEATASIRAQNKRQldrfglgdKQRERLD 86

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 86562857   420 QELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEA 455
Cdd:TIGR01541  87 ARLQIDRTFRKQQRDLNKAMTAKGLAGSDLYKEQLA 122

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

291-601

3.25e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 44.54 E-value: 3.25e-04

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 291 ENEFLNQLLHIVQHQKTVSERQQQEKFEKMEQERLRQEKEEKARELERRRKLEESETARQAELDRQATIY---------- 360
Cdd:COG1196 454 LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAgavavligve 533

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 361 -------------AEQERMAMERNRELERIRLEEKKRENERVRQEEIAMEISKIRELERLQLERQRKNERVRQEL--EAA 425
Cdd:COG1196 534 aayeaaleaalaaALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLreADA 613

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 426 RKYKLQEEERQRKIQQQKVEMEqIRQQEEARQEQLRVLEEERARELERVRQEELERQHQMEILRQQEEDQKKKKLEKDRE 505
Cdd:COG1196 614 RYYVLGDTLLGRTLVAARLEAA-LRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEE 692

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 506 QREQQEaeelnrmiiEKEMKENKQKMIEEKNKRKMLEKEMEDRQNAIYEEEERRIAEEERRKQIEIEERRRIQQQIMIAT 585
Cdd:COG1196 693 LELEEA---------LLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLE 763

                       330
                ....*....|....*.
gi 86562857 586 EERSRLDAMEREREML 601
Cdd:COG1196 764 ELERELERLEREIEAL 779

CCDC34

Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several ...

310-460

3.50e-04

Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several conserved tryptophan residues. The function is not known.

Pssm-ID: 464032 [Multi-domain] Cd Length: 221 Bit Score: 43.15 E-value: 3.50e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   310 ERQQQEKFEKMEQERLRQ-EKEEKARELERRRKLEESEtarqaeldrqatiyaEQERMAMERNRELerirLEEKKRENER 388
Cdd:pfam13904  50 ERQPLEAYENWLAAKQRQrQKELQAQKEEREKEEQEAE---------------LRKRLAKEKYQEW----LQRKARQQTK 110

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 86562857   389 VRQEEIAMEISKIRELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKvemEQIRQQEEARQEQL 460
Cdd:pfam13904 111 KREESHKQKAAESASKSLAKPERKVSQEEAKEVLQEWERKKLEQQQRKREEEQRE---QLKKEEEEQERKQL 179

SCP-1

pfam05483

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...

263-619

3.94e-04

Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 44.33 E-value: 3.94e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   263 RRPDSFGVEEL--TTMTPEYTVRYNGQTMTENEFLNQLLhIVQHQKTVSERQQQEKF---EKMEQERLRQ---EKEEKAR 334
Cdd:pfam05483 344 KAAHSFVVTEFeaTTCSLEELLRTEQQRLEKNEDQLKII-TMELQKKSSELEEMTKFknnKEVELEELKKilaEDEKLLD 422

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   335 ELERRRKLEESETARQAEL-----DRQATIYAEQERMAMERNRE---LERIRLEEKKRENERVRQEEIAMEISKI----- 401
Cdd:pfam05483 423 EKKQFEKIAEELKGKEQELifllqAREKEIHDLEIQLTAIKTSEehyLKEVEDLKTELEKEKLKNIELTAHCDKLllenk 502

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   402 ---RELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLRVLEEERARELERVRQEE 478
Cdd:pfam05483 503 eltQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEV 582

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   479 LERQHQMEI-------LRQQEEDQKK--KKLEKDREQREQQEAEElNRMIIEKEMKENKQKMIEEKNKRKMLE------K 543
Cdd:pfam05483 583 LKKEKQMKIlenkcnnLKKQIENKNKniEELHQENKALKKKGSAE-NKQLNAYEIKVNKLELELASAKQKFEEiidnyqK 661

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   544 EMEDRQNAIYE-----EEERRIAEEERRKQIEIEER--RRIQQQIMIATEERSRLDAMEREREMLRQIKESEKQRKELER 616
Cdd:pfam05483 662 EIEDKKISEEKlleevEKAKAIADEAVKLQKEIDKRcqHKIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAK 741


                  ...
gi 86562857   617 QEL 619
Cdd:pfam05483 742 AAL 744

COG4372

Uncharacterized protein, contains DUF3084 domain [Function unknown];

305-552

4.12e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];

Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 43.74 E-value: 4.12e-04

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 305 QKTVSERQQQEKFEKMEQERLRQEKEEKARELERrrkLEESETARQAELDRQATIYAEQERMAMERNRELERIRLEEKKR 384
Cdd:COG4372  44 QEELEQLREELEQAREELEQLEEELEQARSELEQ---LEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEEL 120

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 385 ENERVRQEEIAMEI-SKIRELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLRVL 463
Cdd:COG4372 121 QKERQDLEQQRKQLeAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEKEE 200

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 464 EEERARELERVRQEELERQHQMEILR---------------QQEEDQKKKKLEKDREQREQQEAEELNRMIIEKEMKENK 528
Cdd:COG4372 201 ELAEAEKLIESLPRELAEELLEAKDSleaklglalsalldaLELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEI 280

                       250       260
                ....*....|....*....|....
gi 86562857 529 QKMIEEKNKRKMLEKEMEDRQNAI 552
Cdd:COG4372 281 AALELEALEEAALELKLLALLLNL 304

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

369-619

4.27e-04

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 44.29 E-value: 4.27e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    369 ERNRELERIR--LEEKKRENERVRqeeiAMEISKIRELERLQLER---------QRKNERVRQ-----ELEAARKYK--- 429
Cdd:TIGR02169  167 EFDRKKEKALeeLEEVEENIERLD----LIIDEKRQQLERLRRERekaeryqalLKEKREYEGyellkEKEALERQKeai 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    430 ------LQEE--ERQRKIQQQKVEMEQIRQ-------------QEEARQEQLRVLEEERARELERVRQEELERQ-HQMEI 487
Cdd:TIGR02169  243 erqlasLEEEleKLTEEISELEKRLEEIEQlleelnkkikdlgEEEQLRVKEKIGELEAEIASLERSIAEKERElEDAEE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    488 LRQQEEDQKKKKLEKDREQREQQEAEELNRMIIEKEMKENKQKM------IEEKNKR--------KMLEKEMEDRQNAIY 553
Cdd:TIGR02169  323 RLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELedlraeLEEVDKEfaetrdelKDYREKLEKLKREIN 402

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 86562857    554 EEEERRIAEEERRKQIEiEERRRIQQQIMIATEE-----------RSRLDAMEREREMLRQIKESEKQRKELERQEL 619
Cdd:TIGR02169  403 ELKRELDRLQEELQRLS-EELADLNAAIAGIEAKineleeekedkALEIKKQEWKLEQLAADLSKYEQELYDLKEEY 478

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

334-539

5.09e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 43.99 E-value: 5.09e-04

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 334 RELERRRKLEESETARQAELDRQAtIYAEQERMAMERNRELERIRLEEKKRENERvRQEEIAMEISKIRElERLQLERQR 413
Cdd:COG4717  49 ERLEKEADELFKPQGRKPELNLKE-LKELEEELKEAEEKEEEYAELQEELEELEE-ELEELEAELEELRE-ELEKLEKLL 125

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 414 KNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLRVLEEERARELERVRQEELERQHQMeILRQQEE 493
Cdd:COG4717 126 QLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDL-AEELEEL 204

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*.
gi 86562857 494 DQKKKKLEKDREQREQqeaeelNRMIIEKEMKENKQKMIEEKNKRK 539
Cdd:COG4717 205 QQRLAELEEELEEAQE------ELEELEEELEQLENELEAAALEER 244

DUF4686

pfam15742

Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins ...

311-609

6.13e-04

Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins in this family are typically between 498 and 775 amino acids in length. There is a conserved DLK sequence motif.

Pssm-ID: 464838 [Multi-domain] Cd Length: 384 Bit Score: 43.13 E-value: 6.13e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   311 RQQQEKFEKMEQERLR-------QEKE-----EKARELERRRKLEESETAR-QAELDRQATIYAEQERMAMERNRELERI 377
Cdd:pfam15742   9 YQQQEEVQQLRQNLQRlqilctsAEKElryerGKNLDLKQHNSLLQEENIKiKAELKQAQQKLLDSTKMCSSLTAEWKHC 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   378 RLEEKKRENERVR-----------QEEIAMEISKIRELERLQLERQRKNERVRQ----------------------ELEA 424
Cdd:pfam15742  89 QQKIRELELEVLKqaqsiksqnslQEKLAQEKSRVADAEEKILELQQKLEHAHKvcltdtcilekkqleerikeasENEA 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   425 ARKYKLQEEERQRKIQQQKVE--MEQIR--QQEEARQEQLRVLEEERARELERVRQE-ELERQHQMEILR-QQEEDQKKK 498
Cdd:pfam15742 169 KLKQQYQEEQQKRKLLDQNVNelQQQVRslQDKEAQLEMTNSQQQLRIQQQEAQLKQlENEKRKSDEHLKsNQELSEKLS 248

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   499 KLEKDREQREQQEAEELNRMiiEKEMKENKQKMIEEKNK----RKMLEKEMEDRQNAIyeeEERRIAEEERRKQIEIEER 574
Cdd:pfam15742 249 SLQQEKEALQEELQQVLKQL--DVHVRKYNEKHHHHKAKlrraKDRLVHEVEQRDERI---KQLENEIGILQQQSEKEKA 323

                         330       340       350
                  ....*....|....*....|....*....|....*
gi 86562857   575 RriQQQIMiatEERSRLdaMEREREMLRQIKESEK 609
Cdd:pfam15742 324 F--QKQVT---AQNEIL--LLEKRKLLEQLTEQEE 351

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

339-503

6.21e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 43.75 E-value: 6.21e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  339 RRKLEESETARQAELDRQATIYAEQERMAMERnRELERIRLEEKKRENERVRQEEIAMEISKIRELERlQLERQRKN--- 415
Cdd:COG4913  609 RAKLAALEAELAELEEELAEAEERLEALEAEL-DALQERREALQRLAEYSWDEIDVASAEREIAELEA-ELERLDASsdd 686

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  416 -ERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLRVLEEERARELERVRQEELERQHQmEILRQQEED 494
Cdd:COG4913  687 lAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFA-AALGDAVER 765


                 ....*....
gi 86562857  495 QKKKKLEKD 503
Cdd:COG4913  766 ELRENLEER 774

PRK02224

DNA double-strand break repair Rad50 ATPase;

304-460

6.24e-04

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 43.88 E-value: 6.24e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  304 HQKTVSERQqqEKFEKMEQER--LRQEKEEKARELERRRKLEESETARQAELDRQATIyaeQERMAMERNR-ELERIRLE 380
Cdd:PRK02224 466 HVETIEEDR--ERVEELEAELedLEEEVEEVEERLERAEDLVEAEDRIERLEERREDL---EELIAERRETiEEKRERAE 540

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  381 EKkreneRVRQEEIAMEISKIRELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQL 460
Cdd:PRK02224 541 EL-----RERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKR 615

rne

PRK10811

ribonuclease E; Reviewed

330-496

6.72e-04

ribonuclease E; Reviewed

Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 43.87 E-value: 6.72e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   330 EEKARELERRRKLEESETARQaeldrqatiyaeQERMAMERNREleRIRLEEKKRENERVRQEEiameiskireleRLQL 409
Cdd:PRK10811  583 GEETKPQEQPAPKAEAKPERQ------------QDRRKPRQNNR--RDRNERRDTRDNRTRREG------------RENR 636

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   410 ERQRKNERVRQELEAARKYKLQEEE------RQRKIQQQKVEmEQIRQQEEARQEQLRVLEEERARELERVRQEELERQH 483
Cdd:PRK10811  637 EENRRNRRQAQQQTAETRESQQAEVtekartQDEQQQAPRRE-RQRRRNDEKRQAQQEAKALNVEEQSVQETEQEERVQQ 715

                         170
                  ....*....|...
gi 86562857   484 QMEILRQQEEDQK 496
Cdd:PRK10811  716 VQPRRKQRQLNQK 728

TolA

COG3064

Membrane protein TolA involved in colicin uptake [Cell wall/membrane/envelope biogenesis];

303-621

6.77e-04

Membrane protein TolA involved in colicin uptake [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442298 [Multi-domain] Cd Length: 485 Bit Score: 43.49 E-value: 6.77e-04

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 303 QHQKTVSERQQQEKFEKMEQERLRQEKEEKAR-ELERRRKLEESETARQAEldrqatiYAEQERMAMERNRELERIRLEE 381
Cdd:COG3064  30 EAEQKAKEEAEEERLAELEAKRQAEEEAREAKaEAEQRAAELAAEAAKKLA-------EAEKAAAEAEKKAAAEKAKAAK 102

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 382 KKRENERVRQEEIAMEISKIRELERlQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLR 461
Cdd:COG3064 103 EAEAAAAAEKAAAAAEKEKAEEAKR-KAEEEAKRKAEEERKAAEAEAAAKAEAEAARAAAAAAAAAAAAAARAAAGAAAA 181

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 462 VLEEERARELERVRQEELERQHQMEILRqQEEDQKKKKLEKDREQREQQEAEELNRMIIEKEMKENKQKMIEEKNKRKML 541
Cdd:COG3064 182 LVAAAAAAVEAADTAAAAAAALAAAAAA-AAADAALLALAVAARAAAASREAALAAVEATEEAALGGAEEAADLAAVGVL 260

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 542 EKEMEDRQNAIYEEEERRIAEEERRKQIEIEERRRIQQQIMIATEERSRLDAMEREREMLRQIKESEKQRKELERQELLA 621
Cdd:COG3064 261 GAALAAAAAGAAALSSGLVVVAAALAGLAAAAAGLVLDDSAALAAELLGAVAAEEAVLAAAAAAGALVVRGGGAASLEAA 340

Mplasa_alph_rch

TIGR04523

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...

301-617

7.18e-04

Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 43.47 E-value: 7.18e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   301 IVQHQKTVSERQQQEKFEKMEQERLRQEKEEKARELER-RRKLEESEtarqaelDRQATIYAEQERMAMERNREL-ERIR 378
Cdd:TIGR04523 241 INEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQnNKKIKELE-------KQLNQLKSEISDLNNQKEQDWnKELK 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   379 LEEKKRENE-RVRQEEIAMEISKIRELERL--QLERQRKNERvrqeleaarkykLQEEERQRKIQQQKVEMEQIRQQEEA 455
Cdd:TIGR04523 314 SELKNQEKKlEEIQNQISQNNKIISQLNEQisQLKKELTNSE------------SENSEKQRELEEKQNEIEKLKKENQS 381

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   456 RQEQLrvleeerarelervrqEELERqhQMEILRQQEEDQKKKKLEKDREQREQQEaeelNRMIIEKEMKENKQKMIEEK 535
Cdd:TIGR04523 382 YKQEI----------------KNLES--QINDLESKIQNQEKLNQQKDEQIKKLQQ----EKELLEKEIERLKETIIKNN 439

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   536 NKRKMLEKEMEDRQNAIyeeEERRIAEEERRKQIEIEER--RRIQQQIMIATEErsrLDAMEREREML-RQIKESEKQRK 612
Cdd:TIGR04523 440 SEIKDLTNQDSVKELII---KNLDNTRESLETQLKVLSRsiNKIKQNLEQKQKE---LKSKEKELKKLnEEKKELEEKVK 513


                  ....*
gi 86562857   613 ELERQ 617
Cdd:TIGR04523 514 DLTKK 518

PRK02224

DNA double-strand break repair Rad50 ATPase;

328-601

7.33e-04

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 43.49 E-value: 7.33e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  328 EKEEKARELERRR-KLEESETARQAELDRqATIYAEQERmamERNRELERIRLEEKKRENERVRQEEiameiskirelER 406
Cdd:PRK02224 472 EDRERVEELEAELeDLEEEVEEVEERLER-AEDLVEAED---RIERLEERREDLEELIAERRETIEE-----------KR 536

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  407 LQLERQRKN-ERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLRvlEEERARELERVRQEELERQHQM 485
Cdd:PRK02224 537 ERAEELRERaAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLE--RIRTLLAAIADAEDEIERLREK 614

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  486 EILRQQEEDQKKKKLekdreqreqqeaeelnrmiieKEMKENKQKMiEEKNKRKMLEKEMEDRQNAiyeeeeRRIAEEER 565
Cdd:PRK02224 615 REALAELNDERRERL---------------------AEKRERKREL-EAEFDEARIEEAREDKERA------EEYLEQVE 666

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 86562857  566 RKQIEIEERR-RIQQQIMIATEERSRLDAMEREREML 601
Cdd:PRK02224 667 EKLDELREERdDLQAEIGAVENELEELEELRERREAL 703

DUF3584

pfam12128

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...

333-622

8.46e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.

Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 43.29 E-value: 8.46e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    333 ARELERRRKLEESETARQAELDRQAtiyAEQERMAmernreLERIRLEEKKRENERVRQeeiAMEISKIReLERLQLERQ 412
Cdd:pfam12128  597 ASEEELRERLDKAEEALQSAREKQA---AAEEQLV------QANGELEKASREETFART---ALKNARLD-LRRLFDEKQ 663

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    413 RKNERVRQELEAARKYKlqEEERQRKIQQQKVEMEQIRQQEEARQEQLRVLEEERARELERVRQE---ELERQHQMEILR 489
Cdd:pfam12128  664 SEKDKKNKALAERKDSA--NERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGAldaQLALLKAAIAAR 741

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    490 QQEEDQKKKKLEKDREQREQQEAEELNRMIIEKEMKENKQKMIEEKNKRKMLEKEMEDRQNAIYEEEERRIAEEERRKQI 569
Cdd:pfam12128  742 RSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIER 821

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 86562857    570 EIEERRriQQQIMIATEERSRLDAMEREREMLR--QIKESEKQRKELERQELLAT 622
Cdd:pfam12128  822 AISELQ--QQLARLIADTKLRRAKLEMERKASEkqQVRLSENLRGLRCEMSKLAT 874

DUF3584

pfam12128

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...

282-460

1.01e-03

Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 43.29 E-value: 1.01e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    282 VRYNGQTMTENEFLNQLLHIVQHQKTVSERQQQEkfekMEQERLRQEKEEKARELERRRKLEESETARQAELD-----RQ 356
Cdd:pfam12128  667 DKKNKALAERKDSANERLNSLEAQLKQLDKKHQA----WLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKaaiaaRR 742

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    357 ATIYAEQERMAMERNREL-------ERIRLEEKKRENERVRQEEIAMEISKIRELERLQLER--QRKNERVRQELEAARK 427
Cdd:pfam12128  743 SGAKAELKALETWYKRDLaslgvdpDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETwlQRRPRLATQLSNIERA 822

                          170       180       190
                   ....*....|....*....|....*....|...
gi 86562857    428 YKLQEEERQRKIQQQKVEMEQIRQQEEARQEQL 460
Cdd:pfam12128  823 ISELQQQLARLIADTKLRRAKLEMERKASEKQQ 855

ChtBD2

smart00494

Chitin-binding domain type 2;

692-744

1.02e-03

Chitin-binding domain type 2;

Pssm-ID: 214696 [Multi-domain] Cd Length: 49 Bit Score: 37.81 E-value: 1.02e-03

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 86562857    692 GECElkYDVDSFCAHPRSPSMYLQCAPlygrlGRWTERYCPDTLIFIVSIGRC 744
Cdd:smart00494   1 NECP--GRGDGLYPHPTDCSKYYQCSN-----GRPIVGSCPAGLVFNPATQTC 46

PLN02316

synthase/transferase

330-384

1.14e-03

synthase/transferase

Pssm-ID: 215180 [Multi-domain] Cd Length: 1036 Bit Score: 42.94 E-value: 1.14e-03

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 86562857   330 EEKARELERRRKlEESETARQAELDRQatiyAEQERMAMERNRELERIRLEEKKR 384
Cdd:PLN02316  252 EEKRRELEKLAK-EEAERERQAEEQRR----REEEKAAMEADRAQAKAEVEKRRE 301

MukB

COG3096

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

318-502

1.15e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 43.02 E-value: 1.15e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  318 EKMEQERLRQEKEEKARELERRRKLEESETARQAELDRQatiYAEQERmAMERNRELERIRLEEKKRENERVRQEEiame 397
Cdd:COG3096  482 CKIAGEVERSQAWQTARELLRRYRSQQALAQRLQQLRAQ---LAELEQ-RLRQQQNAERLLEEFCQRIGQQLDAAE---- 553

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  398 iskirELERLQLERQRKNERVRQELEAARkyklqeeERQRKIQQQKVEMEQIRQQEEARQ----------EQLRVLEEER 467
Cdd:COG3096  554 -----ELEELLAELEAQLEELEEQAAEAV-------EQRSELRQQLEQLRARIKELAARApawlaaqdalERLREQSGEA 621

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 86562857  468 ---ARELERVRQEELERQHQMEILRQQEEdQKKKKLEK 502
Cdd:COG3096  622 ladSQEVTAAMQQLLEREREATVERDELA-ARKQALES 658

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

374-552

1.16e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 42.83 E-value: 1.16e-03

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 374 LERIRLEEKKRENERVRQEEIAMEISKIRELERLQLERQRKNERVRQELEaarkyKLQEEERQRKIQQQKVEMEQIRQQE 453
Cdd:COG4717  70 LKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELE-----KLEKLLQLLPLYQELEALEAELAEL 144

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 454 EARQEQLRvleeerareleRVRQEELERQHQMEILRQQEEdQKKKKLEKDREQREQQEAEELNRMIIEKEMKENKQKMIE 533
Cdd:COG4717 145 PERLEELE-----------ERLEELRELEEELEELEAELA-ELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELE 212

                       170
                ....*....|....*....
gi 86562857 534 EKNKRkmLEKEMEDRQNAI 552
Cdd:COG4717 213 EELEE--AQEELEELEEEL 229

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

410-618

1.22e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 42.44 E-value: 1.22e-03

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 410 ERQRKNERVRQELEAARKyKLQEEERQRKIQQQkvEMEQIRQQEEARQEQLRVLEEERARElervrQEELER-QHQMEIL 488
Cdd:COG4942  24 EAEAELEQLQQEIAELEK-ELAALKKEEKALLK--QLAALERRIAALARRIRALEQELAAL-----EAELAElEKEIAEL 95

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 489 RQQEEDQKKKKLEKDREQREQQEAEELNRMIiekemkeNKQKMIEEKNKRKMLEKEMEDRQNAIYEEEERRIAEEERRKQ 568
Cdd:COG4942  96 RAELEAQKEELAELLRALYRLGRQPPLALLL-------SPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAE 168

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*
gi 86562857 569 IEiEERRRIQQQIMIATEERSRLDAMEREREML-----RQIKESEKQRKELERQE 618
Cdd:COG4942 169 LE-AERAELEALLAELEEERAALEALKAERQKLlarleKELAELAAELAELQQEA 222

PRK00409

recombination and DNA strand exchange inhibitor protein; Reviewed

309-460

1.27e-03

recombination and DNA strand exchange inhibitor protein; Reviewed

Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 42.89 E-value: 1.27e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  309 SERQQQEKFEKMEQ-----ERLRQEKEEKARELERRRKleesetarqaeldrqaTIYAEQERMAmernreleRIRLEEKK 383
Cdd:PRK00409 528 LERELEQKAEEAEAllkeaEKLKEELEEKKEKLQEEED----------------KLLEEAEKEA--------QQAIKEAK 583

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 86562857  384 RENERVrqeeiameISKIRELERLQLERQRknervRQELEAARK-YKLQEEERQRKIQQQKVEMEQIRQQEEARQEQL 460
Cdd:PRK00409 584 KEADEI--------IKELRQLQKGGYASVK-----AHELIEARKrLNKANEKKEKKKKKQKEKQEELKVGDEVKYLSL 648

RNase_Y_N

pfam12072

RNase Y N-terminal region;

323-461

1.29e-03

RNase Y N-terminal region;

Pssm-ID: 463456 [Multi-domain] Cd Length: 201 Bit Score: 41.02 E-value: 1.29e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   323 ERLRQEKEEKARELerrrkLEESEtaRQAE-LDRQATIYAEQE--RMAMERNRELERIRLEEKKRENeRVRQEEIAMEiS 399
Cdd:pfam12072  26 EAKIGSAEELAKRI-----IEEAK--KEAEtKKKEALLEAKEEihKLRAEAERELKERRNELQRQER-RLLQKEETLD-R 96

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 86562857   400 KIRELErlqlERQRKNERVRQELEAARKY-KLQEEERQRKIQQQKVEMEQIR--QQEEARQEQLR 461
Cdd:pfam12072  97 KDESLE----KKEESLEKKEKELEAQQQQlEEKEEELEELIEEQRQELERISglTSEEAKEILLD 157

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

287-461

1.37e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.59 E-value: 1.37e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  287 QTMTENEFLNQLLHIVQHQKTVSERQQQEKFEKMEQERLRQEKEEKARELER-RRKLEESETA-RQAELDRQATIyaeqe 364
Cdd:COG4913  269 ERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDAlREELDELEAQiRGNGGDRLEQL----- 343

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  365 rmamerNRELERIRLEEKKRENERVRQEEIAMEISKIRELERLQLERQRknERVRQELEAARKYKLQEEERQRKIQQQKV 444
Cdd:COG4913  344 ------EREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALR--AEAAALLEALEEELEALEEALAEAEAALR 415

                        170
                 ....*....|....*..
gi 86562857  445 EMEQIRQQEEARQEQLR 461
Cdd:COG4913  416 DLRRELRELEAEIASLE 432

DR0291

COG1579

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...

321-501

1.66e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];

Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.06 E-value: 1.66e-03

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 321 EQERLR--QEKEEKARELERRRK-LEESETARQAELDRQATIYAEQERMAMERNRELERIRLEEKKRENERVRQEEIAME 397
Cdd:COG1579   5 DLRALLdlQELDSELDRLEHRLKeLPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGN 84

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 398 ISKIRELERLQlerqrknervrQELEAARKYKLQEEERQR----KIQQQKVEMEQIRQQEEARQEQLRVleeerareler 473
Cdd:COG1579  85 VRNNKEYEALQ-----------KEIESLKRRISDLEDEILelmeRIEELEEELAELEAELAELEAELEE----------- 142

                       170       180
                ....*....|....*....|....*...
gi 86562857 474 vrqEELERQHQMEILRQQEEDQKKKKLE 501
Cdd:COG1579 143 ---KKAELDEELAELEAELEELEAEREE 167

COG5022

Myosin heavy chain [General function prediction only];

310-657

1.76e-03

Myosin heavy chain [General function prediction only];

Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 42.37 E-value: 1.76e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  310 ERQQQEKFEKMEQERLRQEKEEKARELER---RRKLEESETA--RQAELDRQATIYAEQERM--AMERNREL----ERI- 377
Cdd:COG5022  816 LACIIKLQKTIKREKKLRETEEVEFSLKAevlIQKFGRSLKAkkRFSLLKKETIYLQSAQRVelAERQLQELkidvKSIs 895

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  378 -----------RLEEKKRENERVRQEEIAMEISKIRELERLQLERQRKNERVRQELEAARKYKLQEEErqRKIQQQKVEM 446
Cdd:COG5022  896 slklvnlelesEIIELKKSLSSDLIENLEFKTELIARLKKLLNNIDLEEGPSIEYVKLPELNKLHEVE--SKLKETSEEY 973

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  447 EQIRQQEEARQEQLRvleeerarelerVRQEELERQHQM--EILRQQEEDQKKKKLEKDREQREQQEAeelNRMIIEKEM 524
Cdd:COG5022  974 EDLLKKSTILVREGN------------KANSELKNFKKElaELSKQYGALQESTKQLKELPVEVAELQ---SASKIISSE 1038

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  525 KENKQKMIEEKNKRKMLEKEMEDRQNAIYEEEERRIAEEERRKQIEIEER-----RRIQQQIMIATEERSRLDAMERERE 599
Cdd:COG5022 1039 STELSILKPLQKLKGLLLLENNQLQARYKALKLRRENSLLDDKQLYQLEStenllKTINVKDLEVTNRNLVKPANVLQFI 1118

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 86562857  600 MLRQIKESEKQRKELERQELLATTPI---TTIKPIYRPDISEYRPPDVE-SHMIRFTTQSPE 657
Cdd:COG5022 1119 VAQMIKLNLLQEISKFLSQLVNTLEPvfqKLSVLQLELDGLFWEANLEAlPSPPPFAALSEK 1180

CwlO1

COG3883

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...

301-497

1.88e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];

Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 41.74 E-value: 1.88e-03

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 301 IVQHQKTVSERQQQEKFEKMEQERLRQEKEEKARELErrrKLEESETARQAELDR-QATIYAEQERMAmERNRELERiRL 379
Cdd:COG3883  18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYN---ELQAELEALQAEIDKlQAEIAEAEAEIE-ERREELGE-RA 92

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 380 EEKKRENERVRQEEIAME-------ISKIRELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQ 452
Cdd:COG3883  93 RALYRSGGSVSYLDVLLGsesfsdfLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAE 172

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*
gi 86562857 453 EEARQEQLRVleeeraRELERVRQEELERQHQMEILRQQEEDQKK 497
Cdd:COG3883 173 LEAQQAEQEA------LLAQLSAEEAAAEAQLAELEAELAAAEAA 211

CHASE3

COG5278

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];

402-628

1.93e-03

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];

Pssm-ID: 444089 [Multi-domain] Cd Length: 530 Bit Score: 41.82 E-value: 1.93e-03

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 402 RELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLRVLEEERARELERVRQEELER 481
Cdd:COG5278 107 ARLDELEALIDQWLAELEQVIALRRAGGLEAALALVRSGEGKALMDEIRARLLLLALALAALLLAAAALLLLLLALAALL 186

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 482 QHQMEILRQQEEDQKKKKLEKDREQREQQEAEELNRMIIEKEMKENKQKMIEEKNKRKMLEKEMEDRQNAIYEEEERRIA 561
Cdd:COG5278 187 ALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAALALALALLLAALLLALLAALALAALLAAA 266

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 86562857 562 EEERRKQIEIEERRRIQQQIMIATEERSRLDAMEREREMLRQIKESEKQRKELERQELLATTPITTI 628
Cdd:COG5278 267 LLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAAAAAAAAAAAALAALLALAL 333

mukB

PRK04863

chromosome partition protein MukB;

337-461

1.96e-03

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 42.25 E-value: 1.96e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   337 ERRRKLEESETARQAELDRQATIYAEQERmAMERNRELERIRLEEKKREnervrqeeiaMEISKIRelERLQLER----- 411
Cdd:PRK04863  280 ERRVHLEEALELRRELYTSRRQLAAEQYR-LVEMARELAELNEAESDLE----------QDYQAAS--DHLNLVQtalrq 346

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 86562857   412 QRKNERVRQELEAArKYKLQEEERQRKIQQQKVEMEQiRQQEEARQEQLR 461
Cdd:PRK04863  347 QEKIERYQADLEEL-EERLEEQNEVVEEADEQQEENE-ARAEAAEEEVDE 394

PRK12705

hypothetical protein; Provisional

311-445

1.97e-03

hypothetical protein; Provisional

Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 42.00 E-value: 1.97e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  311 RQQQEKFEKMEQERLRQEKEEKARELERRRKLEESETARQAELDRQATIYAEQERMAMERNRELErirLEEKKRENERVR 390
Cdd:PRK12705  58 KELLLRERNQQRQEARREREELQREEERLVQKEEQLDARAEKLDNLENQLEEREKALSARELELE---ELEKQLDNELYR 134

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 86562857  391 QEEIAMEISKIRELERLQLE-RQRKNERVRQELEAARkykLQEEERQRKIQQQKVE 445
Cdd:PRK12705 135 VAGLTPEQARKLLLKLLDAElEEEKAQRVKKIEEEAD---LEAERKAQNILAQAMQ 187

CCDC34

Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several ...

303-425

2.03e-03

Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several conserved tryptophan residues. The function is not known.

Pssm-ID: 464032 [Multi-domain] Cd Length: 221 Bit Score: 40.84 E-value: 2.03e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   303 QHQKTVSERQQQEKFEKMEQERLRQEKEEKARELE-RRRKLEESETARQAELDRQATIYAEQERMAMERNRELERIRLEE 381
Cdd:pfam13904  65 QRQRQKELQAQKEEREKEEQEAELRKRLAKEKYQEwLQRKARQQTKKREESHKQKAAESASKSLAKPERKVSQEEAKEVL 144

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 86562857   382 KKRENERVRQEEiameiSKIRELERLQLERQRKNERVRQELEAA 425
Cdd:pfam13904 145 QEWERKKLEQQQ-----RKREEEQREQLKKEEEEQERKQLAEKA 183

GBP_C

pfam02841

Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral ...

356-461

2.09e-03

Pssm-ID: 460721 [Multi-domain] Cd Length: 297 Bit Score: 41.12 E-value: 2.09e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   356 QATIYAEQERMAMERNRELERIRLEEKKRENERVRQEEIAMEiskirelERLQLERQRKNERVRQ---ELEAARKYKLQE 432
Cdd:pfam02841 190 EAILQTDQALTAKEKAIEAERAKAEAAEAEQELLREKQKEEE-------QMMEAQERSYQEHVKQlieKMEAEREQLLAE 262

                          90       100       110
                  ....*....|....*....|....*....|..
gi 86562857   433 EER---QRKIQQQKVEMEQIRQQEEARQEQLR 461
Cdd:pfam02841 263 QERmleHKLQEQEELLKEGFKTEAESLQKEIQ 294

Uup

COG0488

ATPase components of ABC transporters with duplicated ATPase domains [General function ...

315-390

2.25e-03

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];

Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 41.59 E-value: 2.25e-03

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 315 EKFEKMEQERLRQEKEEKARELERRRKLEE-----SETARQAeldRQAtiyaeQERMAMernreLERIRLEEKKRENERV 389
Cdd:COG0488 235 SAYLEQRAERLEQEAAAYAKQQKKIAKEEEfirrfRAKARKA---KQA-----QSRIKA-----LEKLEREEPPRRDKTV 301


                .
gi 86562857 390 R 390
Cdd:COG0488 302 E 302

PRK12704

phosphodiesterase; Provisional

310-434

2.56e-03

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 41.69 E-value: 2.56e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  310 ERQQQEKFE--KMEQERLRQEKEEKARELERRRKLEESetarqaELDRQATIYAEQERMAMERNRELERIR--LEEKKRE 385
Cdd:PRK12704  59 LLEAKEEIHklRNEFEKELRERRNELQKLEKRLLQKEE------NLDRKLELLEKREEELEKKEKELEQKQqeLEKKEEE 132

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 86562857  386 NERVRQEEIAmeiskirELER---LQLE--RQRKNERVRQEL--EAARKYKLQEEE 434
Cdd:PRK12704 133 LEELIEEQLQ-------ELERisgLTAEeaKEILLEKVEEEArhEAAVLIKEIEEE 181

MukB

COG3096

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

337-458

2.58e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 41.86 E-value: 2.58e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  337 ERRRKLEESETARQAELDRQATIYAEQERMAmERNRElerirLEEKKRenervRQEEIAMEISKIRE-LERLQ--LERQR 413
Cdd:COG3096  279 ERRELSERALELRRELFGARRQLAEEQYRLV-EMARE-----LEELSA-----RESDLEQDYQAASDhLNLVQtaLRQQE 347

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 86562857  414 KNERVRQELEAArKYKLQEEERQRKIQQQKVEMEQIRqQEEARQE 458
Cdd:COG3096  348 KIERYQEDLEEL-TERLEEQEEVVEEAAEQLAEAEAR-LEAAEEE 390

GBP_C

cd16269

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...

419-549

2.63e-03

Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 41.02 E-value: 2.63e-03

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 419 RQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQlrvleeerarelervrqeelERQHQmEILRQQEE--DQK 496
Cdd:cd16269 191 QALTEKEKEIEAERAKAEAAEQERKLLEEQQRELEQKLEDQ--------------------ERSYE-EHLRQLKEkmEEE 249

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....
gi 86562857 497 KKKLEKDreqreqqeaeelNRMIIEKEMKENKQKMIEE-KNKRKMLEKEMEDRQ 549
Cdd:cd16269 250 RENLLKE------------QERALESKLKEQEALLEEGfKEQAELLQEEIRSLK 291

PstA

COG4985

ABC-type phosphate transport system, auxiliary component PstA [Inorganic ion transport and ...

336-412

2.93e-03

ABC-type phosphate transport system, auxiliary component PstA [Inorganic ion transport and metabolism];

Pssm-ID: 444009 [Multi-domain] Cd Length: 545 Bit Score: 41.44 E-value: 2.93e-03

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 336 LERRRKLEESETAR---QAELDRQATIYAEQERMamER------NRELERIRLEEKKRENERVRQEEIAMEIskirELER 406
Cdd:COG4985 144 KEDGQVVAEGDAAWeelQQRLERALELRDQIDDI--EKgdigaiNYQLERLRLKERRLELDGQLDDEAQADI----EAER 217


                ....*.
gi 86562857 407 LQLERQ 412
Cdd:COG4985 218 AELEAE 223

CCDC34

Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several ...

310-451

2.97e-03

Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several conserved tryptophan residues. The function is not known.

Pssm-ID: 464032 [Multi-domain] Cd Length: 221 Bit Score: 40.46 E-value: 2.97e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   310 ERQQQEKFEKMEQERLRQEKEEKARELERRRKLEESETARQAELDRQATIYAEQERMAMERNRELERIRLEEKKREnerv 389
Cdd:pfam13904  67 QRQKELQAQKEEREKEEQEAELRKRLAKEKYQEWLQRKARQQTKKREESHKQKAAESASKSLAKPERKVSQEEAKE---- 142

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 86562857   390 rqeeiameisKIRELERLQLERQrknERVRQELEAARKYKLQEEERQRKIQQQKVE--MEQIRQ 451
Cdd:pfam13904 143 ----------VLQEWERKKLEQQ---QRKREEEQREQLKKEEEEQERKQLAEKAWQkwMKNVKN 193

PRK03918

DNA double-strand break repair ATPase Rad50;

323-616

3.25e-03

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 41.59 E-value: 3.25e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  323 ERLRQEKEEKARELERRRKLEESETARQAELDRQATIYaeqeRMAMERNRELERIRLEEKKRENERV---------RQEE 393
Cdd:PRK03918 327 EERIKELEEKEERLEELKKKLKELEKRLEELEERHELY----EEAKAKKEELERLKKRLTGLTPEKLekeleelekAKEE 402

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  394 IAMEISKIR-ELERLQLERQRKNERVrQELEAAR------KYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLR-VLEE 465
Cdd:PRK03918 403 IEEEISKITaRIGELKKEIKELKKAI-EELKKAKgkcpvcGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERkLRKE 481

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  466 ERARELERVRQEELERQHQM-EILRQQEEDQKK---KKLEKDRE--------------------------QREQQEAEEL 515
Cdd:PRK03918 482 LRELEKVLKKESELIKLKELaEQLKELEEKLKKynlEELEKKAEeyeklkekliklkgeikslkkeleklEELKKKLAEL 561

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  516 NRMI--IEKEMKENKQKMIEEKNKRkmlEKEMEDRQNAIYEEEERRIAEEERRKQIEIEERRriqqqimIATEERSRLDA 593
Cdd:PRK03918 562 EKKLdeLEEELAELLKELEELGFES---VEELEERLKELEPFYNEYLELKDAEKELEREEKE-------LKKLEEELDKA 631

                        330       340
                 ....*....|....*....|...
gi 86562857  594 MEREREMLRQIKESEKQRKELER 616
Cdd:PRK03918 632 FEELAETEKRLEELRKELEELEK 654

GBP_C

cd16269

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...

303-450

3.25e-03

Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 40.64 E-value: 3.25e-03

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 303 QHQKTVSE--RQQQEKFEKMEQERLRQEKEEKARELERRRKleesetarqaeldrqatiyaeqermaMERNRELERIRLE 380
Cdd:cd16269 177 QSKEAEAEaiLQADQALTEKEKEIEAERAKAEAAEQERKLL--------------------------EEQQRELEQKLED 230

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 381 EKKRENERVRQEEIAMEiskiRELERLQLERQRKNERVRQELEAarkykLQEEERQRKIQQQKVEMEQIR 450
Cdd:cd16269 231 QERSYEEHLRQLKEKME----EERENLLKEQERALESKLKEQEA-----LLEEGFKEQAELLQEEIRSLK 291

PRK03918

DNA double-strand break repair ATPase Rad50;

315-501

3.30e-03

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 41.59 E-value: 3.30e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  315 EKFEKMEQERLRQEKEEK--ARELERRRKLEESETARQAELDrqatiyaEQERMAMERNRELERIRLEEKKRENERVRQ- 391
Cdd:PRK03918 525 EEYEKLKEKLIKLKGEIKslKKELEKLEELKKKLAELEKKLD-------ELEEELAELLKELEELGFESVEELEERLKEl 597

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  392 EEIAMEISKIRELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLRVLEEERAREL 471
Cdd:PRK03918 598 EPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAG 677

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 86562857  472 ERVRQEELERQHQ-----MEILRQQEEDQKKKKLE 501
Cdd:PRK03918 678 LRAELEELEKRREeikktLEKLKEELEEREKAKKE 712

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

271-458

3.41e-03

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 41.58 E-value: 3.41e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    271 EELTTMTPEYTVRYNGQTMTENEFLNQLLHIVQHQKTVSERQQQEKFEKMEQERLRQEKEEKARELERRRKLEESETARQ 350
Cdd:TIGR02168  810 AELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEAL 889

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857    351 AELDRQATIYAEQERMAMERNRELERIRLEEKKRENE-RVRQEEIAMEISKIreLERLqLERQRKNERVRQELEAARKYK 429
Cdd:TIGR02168  890 ALLRSELEELSEELRELESKRSELRRELEELREKLAQlELRLEGLEVRIDNL--QERL-SEEYSLTLEEAEALENKIEDD 966

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 86562857    430 LQE-EERQRKIQQQKVE--------MEQIRQQEEARQE 458
Cdd:TIGR02168  967 EEEaRRRLKRLENKIKElgpvnlaaIEEYEELKERYDF 1004

ERM_helical

pfam20492

Ezrin/radixin/moesin, alpha-helical domain; The ERM family consists of three closely-related ...

319-451

3.79e-03

Ezrin/radixin/moesin, alpha-helical domain; The ERM family consists of three closely-related proteins, ezrin, radixin and moesin. Ezrin was first identified as a constituent of microvilli, radixin as a barbed, end-capping actin-modulating protein from isolated junctional fractions, and moesin as a heparin binding protein. A tumour suppressor molecule responsible for neurofibromatosis type 2 (NF2) is highly similar to ERM proteins and has been designated merlin (moesin-ezrin-radixin-like protein). ERM molecules contain 3 domains, an N-terminal globular domain, an extended alpha-helical domain and a charged C-terminal domain (pfam00769). Ezrin, radixin and merlin also contain a polyproline linker region between the helical and C-terminal domains. The N-terminal domain is highly conserved and is also found in merlin, band 4.1 proteins and members of the band 4.1 superfamily, designated the FERM domain. ERM proteins crosslink actin filaments with plasma membranes. They co-localize with CD44 at actin filament plasma membrane interaction sites, associating with CD44 via their N-terminal domains and with actin filaments via their C-terminal domains. This is the alpha-helical domain, which is involved in intramolecular masking of protein-protein interaction sites, regulating the activity of this proteins.

Pssm-ID: 466641 [Multi-domain] Cd Length: 120 Bit Score: 38.36 E-value: 3.79e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   319 KMEQERLRQEKEEKARELErrrklEESETARQAELDRQATIyaeqERMAMERNR-ELERIRLEEKKRENERVRQEEIAME 397
Cdd:pfam20492   1 REEAEREKQELEERLKQYE-----EETKKAQEELEESEETA----EELEEERRQaEEEAERLEQKRQEAEEEKERLEESA 71

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 86562857   398 ISKIRELERLQLERQRKNERVRQELEAARKyklQEEERQRkiQQQKVEMEQIRQ 451
Cdd:pfam20492  72 EMEAEEKEQLEAELAEAQEEIARLEEEVER---KEEEARR--LQEELEEAREEE 120

Mitofilin

pfam09731

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ...

371-502

4.04e-03

Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 40.90 E-value: 4.04e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   371 NRELERIRLEEKKRENERVRQEeiameiskireleRLQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEME--- 447
Cdd:pfam09731 300 SKKLAELKKREEKHIERALEKQ-------------KEELDKLAEELSARLEEVRAADEAQLRLEFEREREEIRESYEekl 366

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   448 --QIRQQEEARQEQLRvleeerareLERVRQE-ELERQHQMEILRQ--QEEDQKKKKLEK 502
Cdd:pfam09731 367 rtELERQAEAHEEHLK---------DVLVEQEiELQREFLQDIKEKveEERAGRLLKLNE 417

COG2433

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];

306-411

4.06e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];

Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 41.00 E-value: 4.06e-03

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 306 KTVSERQQQEKFEKMEQ-----ERLR----------QEKEEKARELERRRKLEESETARQAELDRQATIyaeqermameR 370
Cdd:COG2433 401 KEHEERELTEEEEEIRRleeqvERLEaeveeleaelEEKDERIERLERELSEARSEERREIRKDREISR----------L 470

                        90       100       110       120
                ....*....|....*....|....*....|....*....|.
gi 86562857 371 NRELERIrleEKKRENERVRQEEIAMEISKIRELERLQLER 411
Cdd:COG2433 471 DREIERL---ERELEEERERIEELKRKLERLKELWKLEHSG 508

PspA

COG1842

Phage shock protein A [Transcription, Signal transduction mechanisms];

318-462

4.19e-03

Phage shock protein A [Transcription, Signal transduction mechanisms];

Pssm-ID: 441447 [Multi-domain] Cd Length: 217 Bit Score: 39.81 E-value: 4.19e-03

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 318 EKMEQErLRQEKEEKARELERRRKLEesetARQAELDRQATIYAEQERMAMERNRE-LERIRLEEKKR-ENERVRQEEia 395
Cdd:COG1842  33 RDMEED-LVEARQALAQVIANQKRLE----RQLEELEAEAEKWEEKARLALEKGREdLAREALERKAElEAQAEALEA-- 105

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 86562857 396 meiskirelerlQLERQRknervrqelEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLRV 462
Cdd:COG1842 106 ------------QLAQLE---------EQVEKLKEALRQLESKLEELKAKKDTLKARAKAAKAQEKV 151

tolA

cell envelope integrity inner membrane protein TolA; Provisional

412-551

4.48e-03

cell envelope integrity inner membrane protein TolA; Provisional

Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 40.56 E-value: 4.48e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  412 QRKNERVRQELEAARKyklqEEERQRKIQQQKvemEQIRQQEEARQEQLRVleeerarelervrqEELERQHQMEILRQQ 491
Cdd:PRK09510  62 EQYNRQQQQQKSAKRA----EEQRKKKEQQQA---EELQQKQAAEQERLKQ--------------LEKERLAAQEQKKQA 120

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 86562857  492 EEDQKKKKLEKDREQREQQEAEELNRMIIEKEMK---ENKQKMIEEKNKRKMLEKEMEDRQNA 551
Cdd:PRK09510 121 EEAAKQAALKQKQAEEAAAKAAAAAKAKAEAEAKraaAAAKKAAAEAKKKAEAEAAKKAAAEA 183

MukB

COG3096

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

292-617

4.74e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 41.09 E-value: 4.74e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  292 NEFLNQLLHIVQHQKTVSERQQ-----QEKFEkmEQERLRQEKEEKARELERRRKLEESETAR--------QAELDRQAT 358
Cdd:COG3096  333 SDHLNLVQTALRQQEKIERYQEdleelTERLE--EQEEVVEEAAEQLAEAEARLEAAEEEVDSlksqladyQQALDVQQT 410

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  359 --IYAEQERMAMERNRELERI----------RLEEKKRE----NERVRQEEIAMEISKI--RELER-LQL--------ER 411
Cdd:COG3096  411 raIQYQQAVQALEKARALCGLpdltpenaedYLAAFRAKeqqaTEEVLELEQKLSVADAarRQFEKaYELvckiagevER 490

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  412 QRKNERVRQELEAARKYKLQEEeRQRKIQQQKVEMEQ-IRQQEEAR--QEQLrvleeERARELERVRQEELERQH-QMEI 487
Cdd:COG3096  491 SQAWQTARELLRRYRSQQALAQ-RLQQLRAQLAELEQrLRQQQNAErlLEEF-----CQRIGQQLDAAEELEELLaELEA 564

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  488 LRQQEEDQKKKKLEKdreqreqqeaeelnRMIIEKEMKENKQKMieeknkrkmleKEMEDRQNAiyeeeerriaeeerrk 567
Cdd:COG3096  565 QLEELEEQAAEAVEQ--------------RSELRQQLEQLRARI-----------KELAARAPA---------------- 603

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 86562857  568 QIEIEER-RRIQQQIMIATEERSRLDA-----MEREREMLRQIKESEKQRKELERQ 617
Cdd:COG3096  604 WLAAQDAlERLREQSGEALADSQEVTAamqqlLEREREATVERDELAARKQALESQ 659

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

330-462

5.39e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 40.67 E-value: 5.39e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857  330 EEKARELERRRK----LEESETARQAELDRQATIYAEQERMAMERNRelERIRLEEKKRENERVRQEEIAmeiskiRELE 405
Cdd:COG4913  241 HEALEDAREQIEllepIRELAERYAAARERLAELEYLRAALRLWFAQ--RRLELLEAELEELRAELARLE------AELE 312

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 86562857  406 RLQLERQRKNERVRQELEAARKYKLQEEER-QRKIQQQKVEMEQIRQQEEARQEQLRV 462
Cdd:COG4913  313 RLEARLDALREELDELEAQIRGNGGDRLEQlEREIERLERELEERERRRARLEALLAA 370

PTZ00266

NIMA-related protein kinase; Provisional

173-393

5.64e-03

NIMA-related protein kinase; Provisional

Pssm-ID: 173502 [Multi-domain] Cd Length: 1021 Bit Score: 40.88 E-value: 5.64e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   173 TTPKIVIFASKKNMNNTNRsGESRTQLIRNRNRE---RGNAPAFTRPGRVRTTTPMSVTHATrfvpgiqhkvtvapkEVQ 249
Cdd:PTZ00266  332 PGLQLAAMEKAKHAEAANY-GISPNTLINQRNEEqhgRRSSSCASRQSANNVTNITSITSVT---------------SVA 395

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   250 GMPHTLAPYEKMDRRPDSFGVEELTTMTPEYTVRYNGQTMTENEFLNQLLHIVQHQKTVSERQQQEKFEKMEQERLRQEK 329
Cdd:PTZ00266  396 SVASVASVPSKDDRKYPQDGATHCHAVNGHYGGRVDKDHAERARIEKENAHRKALEMKILEKKRIERLEREERERLERER 475

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 86562857   330 EEK-ARELERRRKLEESETARQaELDRQATiyaeqERMAMERNRELERIRLEEKKRENERVRQEE 393
Cdd:PTZ00266  476 MERiERERLERERLERERLERD-RLERDRL-----DRLERERVDRLERDRLEKARRNSYFLKGME 534

GBP_C

pfam02841

Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral ...

340-443

5.81e-03

Pssm-ID: 460721 [Multi-domain] Cd Length: 297 Bit Score: 39.96 E-value: 5.81e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   340 RKLEESETARQAELDRQATIYAEQERMaMERNRELERiRLEEKKRENervrQEEIAMEISKI-RELERLQLERQRKNERV 418
Cdd:pfam02841 197 QALTAKEKAIEAERAKAEAAEAEQELL-REKQKEEEQ-MMEAQERSY----QEHVKQLIEKMeAEREQLLAEQERMLEHK 270

                          90       100
                  ....*....|....*....|....*..
gi 86562857   419 RQELEAARKYKLQEE--ERQRKIQQQK 443
Cdd:pfam02841 271 LQEQEELLKEGFKTEaeSLQKEIQDLK 297

COG1340

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];

367-618

6.31e-03

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];

Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 39.89 E-value: 6.31e-03

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 367 AMERNRELERIRLEEKKRENERVRQEEIAmEISKIRElerlqlERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEM 446
Cdd:COG1340   8 SSLEELEEKIEELREEIEELKEKRDELNE-ELKELAE------KRDELNAQVKELREEAQELREKRDELNEKVKELKEER 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 447 EQIRQQEEARQEQLRVLEEERARELERVRQ--------EELERQHQMEILRQQEEDQ---KKKKLEKDREQREQQEAeel 515
Cdd:COG1340  81 DELNEKLNELREELDELRKELAELNKAGGSidklrkeiERLEWRQQTEVLSPEEEKElveKIKELEKELEKAKKALE--- 157

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 516 nrmiIEKEMKENKQKMIEEKNKRKMLEKEMEDRQNAIYEEEERRIAEEERRKQI--EIEE-RRRIQQQIMIATEERSRLD 592
Cdd:COG1340 158 ----KNEKLKELRAELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEADELrkEADElHKEIVEAQEKADELHEEII 233

                       250       260
                ....*....|....*....|....*..
gi 86562857 593 AMERE-REMLRQIKESEKQRKELERQE 618
Cdd:COG1340 234 ELQKElRELRKELKKLRKKQRALKREK 260

COG2433

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];

330-461

6.49e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];

Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 40.23 E-value: 6.49e-03

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 330 EEKARELERRRKLEESETARQAELDRQATIYAEQERMamernRELERiRLEEKKRENERVRQEeiameiskIRELERlql 409
Cdd:COG2433 379 EEALEELIEKELPEEEPEAEREKEHEERELTEEEEEI-----RRLEE-QVERLEAEVEELEAE--------LEEKDE--- 441

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*
gi 86562857 410 erqrKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIR---QQEEARQEQLR 461
Cdd:COG2433 442 ----RIERLERELSEARSEERREIRKDREISRLDREIERLErelEEERERIEELK 492

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

295-621

6.54e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 40.14 E-value: 6.54e-03

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 295 LNQLLHIVQHQKTVSERQQ--------QEKFEKMEQERL-RQEKEEKARELERRrkLEESETARQAELDRQATIYAEQER 365
Cdd:COG4717 118 LEKLEKLLQLLPLYQELEAleaelaelPERLEELEERLEeLRELEEELEELEAE--LAELQEELEELLEQLSLATEEELQ 195

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 366 MAMErnrELERIRLEEKKRENERVRQEEIAMEISKIRELERLQLERQRKNERVRQELEAAR------------------- 426
Cdd:COG4717 196 DLAE---ELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLiaaallallglggsllsli 272

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 427 ---------------KYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLRVLEEERARELERVRQEELERQHQMEILRQQ 491
Cdd:COG4717 273 ltiagvlflvlgllaLLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQEL 352

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 492 EEDQKKKKLEKDREQREQQEAEELNRMIIEKEmkENKQKMIEEKNKRKMLEKEMEDRQNAIYEEEERRIAEEERRKQIEI 571
Cdd:COG4717 353 LREAEELEEELQLEELEQEIAALLAEAGVEDE--EELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEEL 430

                       330       340       350       360       370
                ....*....|....*....|....*....|....*....|....*....|
gi 86562857 572 EERrriqqqimIATEERSRLDAMEREREMLRQIKESEKQRKELERQELLA 621
Cdd:COG4717 431 EEE--------LEELEEELEELEEELEELREELAELEAELEQLEEDGELA 472

PLN02316

synthase/transferase

372-442

6.91e-03

synthase/transferase

Pssm-ID: 215180 [Multi-domain] Cd Length: 1036 Bit Score: 40.24 E-value: 6.91e-03

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 86562857   372 RELERIRLEEKKRENERVRQEEIameiskirELERlQLERQRKNERVRQELEAARKYKLQEEERQRKIQQQ 442
Cdd:PLN02316  244 HSFEDFLLEEKRRELEKLAKEEA--------ERER-QAEEQRRREEEKAAMEADRAQAKAEVEKRREKLQN 305

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

429-621

7.56e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 40.14 E-value: 7.56e-03

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 429 KLQEEERQ-RKIQQQKVEM--EQIRQQEEARQEQlrvleEERARELERVRQEELERQHQMEILRQQEE--DQKKKKLEKD 503
Cdd:COG4717  50 RLEKEADElFKPQGRKPELnlKELKELEEELKEA-----EEKEEEYAELQEELEELEEELEELEAELEelREELEKLEKL 124

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857 504 REQREQQEAEELNRMIIE------KEMKENKQKMIEEKNKRKMLEKEMEDRQNAIYEEEERRIAEEERRKQIEIEERRRI 577
Cdd:COG4717 125 LQLLPLYQELEALEAELAelperlEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEEL 204

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*...
gi 86562857 578 QQQIMIATEE----RSRLDAMEREREMLRQIKESEKQRKELERQELLA 621
Cdd:COG4717 205 QQRLAELEEEleeaQEELEELEEELEQLENELEAAALEERLKEARLLL 252

CCDC34

Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several ...

362-502

8.21e-03

Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several conserved tryptophan residues. The function is not known.

Pssm-ID: 464032 [Multi-domain] Cd Length: 221 Bit Score: 38.92 E-value: 8.21e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   362 EQERMAMERNRELERIRLEEKKRENERVRQEEIAMEiSKIRELERLQLERQRKNERvRQELEAARKYKLQEEERQRKIQQ 441
Cdd:pfam13904  69 QKELQAQKEEREKEEQEAELRKRLAKEKYQEWLQRK-ARQQTKKREESHKQKAAES-ASKSLAKPERKVSQEEAKEVLQE 146

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 86562857   442 QkvEMEQIRQQEEARQEqlrvleeerarelervrqeelERQHQMEilRQQEEDQKKKKLEK 502
Cdd:pfam13904 147 W--ERKKLEQQQRKREE---------------------EQREQLK--KEEEEQERKQLAEK 182

KASH_CCD

pfam14662

Coiled-coil region of CCDC155 or KASH; This coiled-coil region is found in the central part of ...

305-461

8.45e-03

Coiled-coil region of CCDC155 or KASH; This coiled-coil region is found in the central part of KASH or Klarsicht/ANC-1/Syne/homology proteins. KASH are a meiosis-specific proteins that localize at telomeres and interact with SUN1, thus being implicated in meiotic chromosome dynamics and homolog pairing.

Pssm-ID: 405365 [Multi-domain] Cd Length: 191 Bit Score: 38.62 E-value: 8.45e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   305 QKTVSERQQQEKFEKMEQERLRQEKEEKARELERRRKLEESETARQAELDRQatiyAEQERMAMERNRELERIRL----- 379
Cdd:pfam14662  28 KATVETREETNAKLLEENLNLRKQAKSQQQAVQKEKLLEEELEDLKLIVNSL----EEARRSLLAQNKQLEKENQsllqe 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86562857   380 EEKKRENERVRQEEIAMEISKIRELERLQLERQRKNErVRQELEAARKYKLQEEERQRKIQQQKVEmEQIRQQEEARQEQ 459
Cdd:pfam14662 104 IESLQEENKKNQAERDKLQKKKKELLKSKACLKEQLH-SCEDLACNRETILIEKTTQIEELKSTVE-EYSSIEEELRAEK 181


                  ..
gi 86562857   460 LR 461
Cdd:pfam14662 182 SR 183

EnvC