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Conserved domains on  [gi|71989522|ref|NP_497641|]
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Cadherin domain-containing protein [Caenorhabditis elegans]

Protein Classification

cadherin repeat domain-containing protein( domain architecture ID 10182011)

cadherin repeat domain-containing protein similar to Homo sapiens desmoglein-2, which is involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion; cadherins are are calcium-dependent cell adhesion proteins that preferentially interact with themselves in connecting cells

CATH:  2.60.40.60
Gene Ontology:  GO:0007156|GO:0005509
PubMed:  17158740|28268172|27782885|11736639
SCOP:  4007535

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 947-1041 8.25e-32

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 120.88  E-value: 8.25e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522  947 YTMEVLENSPPKTIVGKVVARDKDSLENGQIVYRITNGSE--YFGIDEKLGNVYTKRSIDREVISHVDISIVAEDKGVPP 1024
Cdd:cd11304    2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEdgLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPP 81

                         90
                 ....*....|....*..
gi 71989522 1025 RSSTASARISVLDVNDN 1041
Cdd:cd11304   82 LSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 843-938 1.39e-29

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 114.33  E-value: 1.39e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522  843 EISIREDLKLHEPFYVVQASDKDKKKNGEVRYSIISSHPGSSIEIDQFTGQLSTGSLLDYEATRNYKLRVKATDLGIPPR 922
Cdd:cd11304    3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPL 82

                         90
                 ....*....|....*.
gi 71989522  923 SSNMTLFIHVLDVNDN 938
Cdd:cd11304   83 SSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1934-2025 6.05e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 98.15  E-value: 6.05e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 1934 RVPENLRVGSYVATVGAKDVD--NLAPLRYFLVSDSSGQtptHFNIDQFTGTIHLTAPLDFEVLPEHTLTIKATDG---S 2008
Cdd:cd11304    5 SVPENAPPGTVVLTVSATDPDsgENGEVTYSIVSGNEDG---LFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGggpP 81

                         90
                 ....*....|....*..
gi 71989522 2009 FDTFTNLTIFVSDINDN 2025
Cdd:cd11304   82 LSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 645-733 2.46e-22

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 93.53  E-value: 2.46e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522  645 EYHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHILSESSS--FSINPVTGEVFAQKPL---ARGRFHLVVSAKDGGGQ 719
Cdd:cd11304    1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDglFSIDPSTGEITTAKPLdreEQSSYTLTVTATDGGGP 80

                         90
                 ....*....|....
gi 71989522  720 SSENSANIHITVID 733
Cdd:cd11304   81 PLSSTATVTITVLD 94
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 238-328 1.22e-21

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 91.61  E-value: 1.22e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522  238 YTASVSANISIGSHLITVQATDADIGENSRISYDIkkTSAPSNSNFAI-SQSGVITTTASL--LPASTHDVIVVASDHGS 314
Cdd:cd11304    2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSI--VSGNEDGLFSIdPSTGEITTAKPLdrEEQSSYTLTVTATDGGG 79

                         90
                 ....*....|....
gi 71989522  315 PSLSSSAVVTITVL 328
Cdd:cd11304   80 PPLSSTATVTITVL 93
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2235-2330 6.66e-19

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 83.90  E-value: 6.66e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 2235 YYLSLKDSMAHGQKIGQIMASDQDSGENGRVSYRILSGNDLNIVTLNPDTGSIQLNEwndaQLDEFPNATWQILVEARDH 2314
Cdd:cd11304    2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAK----PLDREEQSSYTLTVTATDG 77

                         90
                 ....*....|....*.
gi 71989522 2315 GHPARAAVGKVQVSLK 2330
Cdd:cd11304   78 GGPPLSSTATVTITVL 93
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 546-637 1.15e-18

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 83.13  E-value: 1.15e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522  546 QVEIPEDTPIGTCLVKVVANNSQCGNSKRIRYSL--QNQDEHLTVDTMSGTVCIQKTFDFEKQKSYQTTVIATNANSE-- 621
Cdd:cd11304    3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIvsGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPpl 82

                         90
                 ....*....|....*.
gi 71989522  622 TSTSLISIRLKDVNDN 637
Cdd:cd11304   83 SSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 129-229 1.27e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 77.35  E-value: 1.27e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522  129 LEISEFAQLGTSFALPTVTDGDGPKFDVHRFVILQGNVNNVFKLasrkvnEQLQADLVVNGQLDREFRDKYELLIEAQDG 208
Cdd:cd11304    4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSI------DPSTGEITTAKPLDREEQSSYTLTVTATDG 77

                         90       100
                 ....*....|....*....|.
gi 71989522  209 GKPAKIGQLRCSIEIIDANDN 229
Cdd:cd11304   78 GGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1337-1426 5.87e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 75.43  E-value: 5.87e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 1337 RVNIREDTPTGSIITTVNATVSDDSA-SPISYRF--PLLIDNFSIDQFTGDITLIDTLHWHVTPTYNLIVEAFTSGPG-- 1411
Cdd:cd11304    3 EVSVPENAPPGTVVLTVSATDPDSGEnGEVTYSIvsGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPpl 82

                         90
                 ....*....|....*.
gi 71989522 1412 -TTLLVTVNVDDVNDH 1426
Cdd:cd11304   83 sSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 746-833 7.71e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 75.04  E-value: 7.71e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522  746 YEIRTTEDILPGIAIGSVGAM-------SKVKYSIYSGDQDHNFSIDEDTGKIYVTRYLDADVHDTVLLNIQAT--LPSG 816
Cdd:cd11304    2 YEVSVPENAPPGTVVLTVSATdpdsgenGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATdgGGPP 81

                         90
                 ....*....|....*..
gi 71989522  817 ESNQTQVVIFIEDHNDN 833
Cdd:cd11304   82 LSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2135-2226 9.27e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 75.04  E-value: 9.27e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 2135 EFRFEVMENSKIGLQIGNLS-----GEESREFHYRIQDPEASKIFSID-KFGRLFVAGPIDREQRATHEFQVEIDNEMMT 2208
Cdd:cd11304    1 SYEVSVPENAPPGTVVLTVSatdpdSGENGEVTYSIVSGNEDGLFSIDpSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                         90
                 ....*....|....*...
gi 71989522 2209 SQKVQCKCHVIVLDENDN 2226
Cdd:cd11304   81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1836-1923 1.75e-14

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 71.19  E-value: 1.75e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 1836 TYLSTIDEGLPRGQFIAKLQ------PELAGLTYSIVEGNIDSAFSVDSE-GVIRTNLELDREILERYSLKVIGT--GSG 1906
Cdd:cd11304    1 SYEVSVPENAPPGTVVLTVSatdpdsGENGEVTYSIVSGNEDGLFSIDPStGEITTAKPLDREEQSSYTLTVTATdgGGP 80

                         90
                 ....*....|....*...
gi 71989522 1907 QQIGT-RVDVRVNNLNDN 1923
Cdd:cd11304   81 PLSSTaTVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 459-532 3.01e-13

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 67.72  E-value: 3.01e-13
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 71989522  459 TLTAKDPDLGQNGWIRYSVL---DTELVSIDKETGRIFVPNTIDCNIGSEIKFRVRAEDGGSPALSTDLQVVADLLD 532
Cdd:cd11304   18 TVSATDPDSGENGEVTYSIVsgnEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLSSTATVTITVLD 94
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2446-2534 4.44e-13

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 67.34  E-value: 4.44e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 2446 SYTLQIPISTPAGESVGQMQAIDEDGGVHGVVKYSIS--DRQSTVKIEEHTGIIRLQKPLvSRRNLTIEQITVVAY--SS 2521
Cdd:cd11304    1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVsgNEDGLFSIDPSTGEITTAKPL-DREEQSSYTLTVTATdgGG 79

                         90
                 ....*....|...
gi 71989522 2522 PTKQSKTTVYLEI 2534
Cdd:cd11304   80 PPLSSTATVTITV 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2345-2437 7.08e-13

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 66.57  E-value: 7.08e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 2345 VYEVHVLEDTSVGTVLQKIRASNRLGMRNDGLLYSLKE--HQGKLGIDVKTGELTLKTHLDWESEPIISMYLSVSDGNG- 2421
Cdd:cd11304    1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSgnEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGp 80

                         90
                 ....*....|....*..
gi 71989522 2422 -RSAVVPLKIVVEPVDE 2437
Cdd:cd11304   81 pLSSTATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1638-1723 9.67e-13

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 66.18  E-value: 9.67e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 1638 VVTIEENVGIEDF-KRILAT----GMTEESRFRFQGNAP--KFSINSTTGSISVL-PLDREASQEHLLIIILTDGG--SR 1707
Cdd:cd11304    3 EVSVPENAPPGTVvLTVSATdpdsGENGEVTYSIVSGNEdgLFSIDPSTGEITTAkPLDREEQSSYTLTVTATDGGgpPL 82

                         90
                 ....*....|....*.
gi 71989522 1708 NDSCTVRVTVADQNDN 1723
Cdd:cd11304   83 SSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1051-1136 5.75e-12

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 64.26  E-value: 5.75e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 1051 IVVPAGSPLSTAIGTIVAMDPDKGLNGSVLYR--AQLQSSLFVV-KSNGDVYLRRQLNASDERHQRLSVIVSDQGVPRKS 1127
Cdd:cd11304    4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSivSGNEDGLFSIdPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLS 83


                 ....*....
gi 71989522 1128 VVCHVPVRI 1136
Cdd:cd11304   84 STATVTITV 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2034-2120 1.20e-11

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 63.10  E-value: 1.20e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 2034 YQTTVSPATfSPGQPFAKIEAHDLD--ARGALTYSL-GQGSSSIFRVAPESGALFmkVLPP----AGERYLVTVTATDNG 2106
Cdd:cd11304    2 YEVSVPENA-PPGTVVLTVSATDPDsgENGEVTYSIvSGNEDGLFSIDPSTGEIT--TAKPldreEQSSYTLTVTATDGG 78

                         90
                 ....*....|....
gi 71989522 2107 VPSFSTSVPVSVII 2120
Cdd:cd11304   79 GPPLSSTATVTITV 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 29-118 7.02e-11

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 61.18  E-value: 7.02e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522   29 FTVPESAQIGTRIGWISGK---REESAAPKYFVVfpDEQTSKFLKVDERSGEISTIAHLDYEKRSKFDIVaVKVEESGE- 104
Cdd:cd11304    4 VSVPENAPPGTVVLTVSATdpdSGENGEVTYSIV--SGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLT-VTATDGGGp 80

                         90
                 ....*....|....*...
gi 71989522  105 ----TIDILVEVDDENDN 118
Cdd:cd11304   81 plssTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1734-1817 7.94e-10

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 58.09  E-value: 7.94e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 1734 ELEIAESSRVGDVLHRFRASDMDIGQNGKFSFELLEDSSGSL-DLVPETGDLVLRRL---SSLQSWKIKLRVVDHGVPGL 1809
Cdd:cd11304    3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLfSIDPSTGEITTAKPldrEEQSSYTLTVTATDGGGPPL 82


                 ....*...
gi 71989522 1810 YVEKNLEI 1817
Cdd:cd11304   83 SSTATVTI 90
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1445-1515 4.58e-05

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 44.61  E-value: 4.58e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 71989522 1445 GGMVHRVVAIDLDKDP--EIRYSLKyagSEVAKEFFKIDEKSGEIFVVESSSALSTSFggaglpETLTIRATD 1515
Cdd:cd11304   13 GTVVLTVSATDPDSGEngEVTYSIV---SGNEDGLFSIDPSTGEITTAKPLDREEQSS------YTLTVTATD 76
 
Name Accession Description Interval E-value
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 947-1041 8.25e-32

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 120.88  E-value: 8.25e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522  947 YTMEVLENSPPKTIVGKVVARDKDSLENGQIVYRITNGSE--YFGIDEKLGNVYTKRSIDREVISHVDISIVAEDKGVPP 1024
Cdd:cd11304    2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEdgLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPP 81

                         90
                 ....*....|....*..
gi 71989522 1025 RSSTASARISVLDVNDN 1041
Cdd:cd11304   82 LSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 843-938 1.39e-29

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 114.33  E-value: 1.39e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522  843 EISIREDLKLHEPFYVVQASDKDKKKNGEVRYSIISSHPGSSIEIDQFTGQLSTGSLLDYEATRNYKLRVKATDLGIPPR 922
Cdd:cd11304    3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPL 82

                         90
                 ....*....|....*.
gi 71989522  923 SSNMTLFIHVLDVNDN 938
Cdd:cd11304   83 SSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 860-940 3.31e-25

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 101.27  E-value: 3.31e-25
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522     860 QASDKDKKKNGEVRYSIISSHPGSSIEIDQFTGQLSTGSLLDYEATRNYKLRVKATDLGIPPRSSNMTLFIHVLDVNDNA 939
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 71989522     940 P 940
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1934-2025 6.05e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 98.15  E-value: 6.05e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 1934 RVPENLRVGSYVATVGAKDVD--NLAPLRYFLVSDSSGQtptHFNIDQFTGTIHLTAPLDFEVLPEHTLTIKATDG---S 2008
Cdd:cd11304    5 SVPENAPPGTVVLTVSATDPDsgENGEVTYSIVSGNEDG---LFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGggpP 81

                         90
                 ....*....|....*..
gi 71989522 2009 FDTFTNLTIFVSDINDN 2025
Cdd:cd11304   82 LSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 965-1043 1.11e-22

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 93.95  E-value: 1.11e-22
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522     965 VARDKDSLENGQIVYRITNGSE--YFGIDEKLGNVYTKRSIDREVISHVDISIVAEDKGVPPRSSTASARISVLDVNDNP 1042
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDdgLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 71989522    1043 P 1043
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 645-733 2.46e-22

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 93.53  E-value: 2.46e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522  645 EYHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHILSESSS--FSINPVTGEVFAQKPL---ARGRFHLVVSAKDGGGQ 719
Cdd:cd11304    1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDglFSIDPSTGEITTAKPLdreEQSSYTLTVTATDGGGP 80

                         90
                 ....*....|....
gi 71989522  720 SSENSANIHITVID 733
Cdd:cd11304   81 PLSSTATVTITVLD 94
Cadherin pfam00028
Cadherin domain;
947-1036 5.53e-22

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 92.36  E-value: 5.53e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522    947 YTMEVLENSPPKTIVGKVVARDKDSLENGQIVYRITNGSEY--FGIDEKLGNVYTKRSIDREVISHVDISIVAEDKGVPP 1024
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGgnFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 71989522   1025 RSSTASARISVL 1036
Cdd:pfam00028   81 LSSTATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 238-328 1.22e-21

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 91.61  E-value: 1.22e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522  238 YTASVSANISIGSHLITVQATDADIGENSRISYDIkkTSAPSNSNFAI-SQSGVITTTASL--LPASTHDVIVVASDHGS 314
Cdd:cd11304    2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSI--VSGNEDGLFSIdPSTGEITTAKPLdrEEQSSYTLTVTATDGGG 79

                         90
                 ....*....|....
gi 71989522  315 PSLSSSAVVTITVL 328
Cdd:cd11304   80 PPLSSTATVTITVL 93
Cadherin pfam00028
Cadherin domain;
843-933 4.64e-19

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 84.27  E-value: 4.64e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522    843 EISIREDLKLHEPFYVVQASDKDKKKNGEVRYSIISSHPGSSIEIDQFTGQLSTGSLLDYEATRNYKLRVKATDLGIPPR 922
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPL 81

                           90
                   ....*....|.
gi 71989522    923 SSNMTLFIHVL 933
Cdd:pfam00028   82 SSTATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2235-2330 6.66e-19

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 83.90  E-value: 6.66e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 2235 YYLSLKDSMAHGQKIGQIMASDQDSGENGRVSYRILSGNDLNIVTLNPDTGSIQLNEwndaQLDEFPNATWQILVEARDH 2314
Cdd:cd11304    2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAK----PLDREEQSSYTLTVTATDG 77

                         90
                 ....*....|....*.
gi 71989522 2315 GHPARAAVGKVQVSLK 2330
Cdd:cd11304   78 GGPPLSSTATVTITVL 93
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 546-637 1.15e-18

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 83.13  E-value: 1.15e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522  546 QVEIPEDTPIGTCLVKVVANNSQCGNSKRIRYSL--QNQDEHLTVDTMSGTVCIQKTFDFEKQKSYQTTVIATNANSE-- 621
Cdd:cd11304    3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIvsGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPpl 82

                         90
                 ....*....|....*.
gi 71989522  622 TSTSLISIRLKDVNDN 637
Cdd:cd11304   83 SSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1951-2027 1.19e-16

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 77.00  E-value: 1.19e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522    1951 KDVDNLAPLRYFLVSDSSGQtptHFNIDQFTGTIHLTAPLDFEVLPEHTLTIKATDG---SFDTFTNLTIFVSDINDNAP 2027
Cdd:smart00112    5 ADSGENGKVTYSILSGNDDG---LFSIDPETGEITTTKPLDREEQPEYTLTVEATDGggpPLSSTATVTITVLDVNDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 129-229 1.27e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 77.35  E-value: 1.27e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522  129 LEISEFAQLGTSFALPTVTDGDGPKFDVHRFVILQGNVNNVFKLasrkvnEQLQADLVVNGQLDREFRDKYELLIEAQDG 208
Cdd:cd11304    4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSI------DPSTGEITTAKPLDREEQSSYTLTVTATDG 77

                         90       100
                 ....*....|....*....|.
gi 71989522  209 GKPAKIGQLRCSIEIIDANDN 229
Cdd:cd11304   78 GGPPLSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
238-328 1.35e-16

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 76.96  E-value: 1.35e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522    238 YTASVSANISIGSHLITVQATDADIGENSRISYDIKKTsaPSNSNFAISQ-SGVITTTASL--LPASTHDVIVVASDHGS 314
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGG--GPGGNFRIDPdTGDISTTKPLdrESIGEYELTVEATDSGG 78

                           90
                   ....*....|....
gi 71989522    315 PSLSSSAVVTITVL 328
Cdd:pfam00028   79 PPLSSTATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1337-1426 5.87e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 75.43  E-value: 5.87e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 1337 RVNIREDTPTGSIITTVNATVSDDSA-SPISYRF--PLLIDNFSIDQFTGDITLIDTLHWHVTPTYNLIVEAFTSGPG-- 1411
Cdd:cd11304    3 EVSVPENAPPGTVVLTVSATDPDSGEnGEVTYSIvsGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPpl 82

                         90
                 ....*....|....*.
gi 71989522 1412 -TTLLVTVNVDDVNDH 1426
Cdd:cd11304   83 sSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 746-833 7.71e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 75.04  E-value: 7.71e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522  746 YEIRTTEDILPGIAIGSVGAM-------SKVKYSIYSGDQDHNFSIDEDTGKIYVTRYLDADVHDTVLLNIQAT--LPSG 816
Cdd:cd11304    2 YEVSVPENAPPGTVVLTVSATdpdsgenGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATdgGGPP 81

                         90
                 ....*....|....*..
gi 71989522  817 ESNQTQVVIFIEDHNDN 833
Cdd:cd11304   82 LSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2135-2226 9.27e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 75.04  E-value: 9.27e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 2135 EFRFEVMENSKIGLQIGNLS-----GEESREFHYRIQDPEASKIFSID-KFGRLFVAGPIDREQRATHEFQVEIDNEMMT 2208
Cdd:cd11304    1 SYEVSVPENAPPGTVVLTVSatdpdSGENGEVTYSIVSGNEDGLFSIDpSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                         90
                 ....*....|....*...
gi 71989522 2209 SQKVQCKCHVIVLDENDN 2226
Cdd:cd11304   81 PLSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 664-735 3.46e-15

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 72.77  E-value: 3.46e-15
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 71989522     664 SASDMDSGTFGEVSYHILSES--SSFSINPVTGEVFAQKPL---ARGRFHLVVSAKDGGGQSSENSANIHITVIDKD 735
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNddGLFSIDPETGEITTTKPLdreEQPEYTLTVEATDGGGPPLSSTATVTITVLDVN 77
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1836-1923 1.75e-14

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 71.19  E-value: 1.75e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 1836 TYLSTIDEGLPRGQFIAKLQ------PELAGLTYSIVEGNIDSAFSVDSE-GVIRTNLELDREILERYSLKVIGT--GSG 1906
Cdd:cd11304    1 SYEVSVPENAPPGTVVLTVSatdpdsGENGEVTYSIVSGNEDGLFSIDPStGEITTAKPLDREEQSSYTLTVTATdgGGP 80

                         90
                 ....*....|....*...
gi 71989522 1907 QQIGT-RVDVRVNNLNDN 1923
Cdd:cd11304   81 PLSSTaTVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 145-231 2.27e-14

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 70.46  E-value: 2.27e-14
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522     145 TVTDGDGPKFDVHRFVILQGNVNNVFKLasrkvnEQLQADLVVNGQLDREFRDKYELLIEAQDGGKPAKIGQLRCSIEII 224
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSI------DPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVL 74


                    ....*..
gi 71989522     225 DANDNAP 231
Cdd:smart00112   75 DVNDNAP 81
Cadherin pfam00028
Cadherin domain;
1934-2019 4.39e-14

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 70.02  E-value: 4.39e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522   1934 RVPENLRVGSYVATVGAKDVDnLAP---LRYFLVSDSSGQtptHFNIDQFTGTIHLTAPLDFEVLPEHTLTIKATDGSF- 2009
Cdd:pfam00028    4 SVPENAPVGTEVLTVTATDPD-LGPngrIFYSILGGGPGG---NFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGp 79

                           90
                   ....*....|..
gi 71989522   2010 --DTFTNLTIFV 2019
Cdd:pfam00028   80 plSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 764-835 1.34e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 68.15  E-value: 1.34e-13
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 71989522     764 GAMSKVKYSIYSGDQDHNFSIDEDTGKIYVTRYLDADVHDTVLLNIQATLPSGE--SNQTQVVIFIEDHNDNPP 835
Cdd:smart00112    8 GENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPplSSTATVTITVLDVNDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 459-532 3.01e-13

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 67.72  E-value: 3.01e-13
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 71989522  459 TLTAKDPDLGQNGWIRYSVL---DTELVSIDKETGRIFVPNTIDCNIGSEIKFRVRAEDGGSPALSTDLQVVADLLD 532
Cdd:cd11304   18 TVSATDPDSGENGEVTYSIVsgnEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLSSTATVTITVLD 94
Cadherin pfam00028
Cadherin domain;
646-732 3.46e-13

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 67.33  E-value: 3.46e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522    646 YHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHILSESSS--FSINPVTGEVFAQKPL---ARGRFHLVVSAKDGGGQS 720
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGgnFRIDPDTGDISTTKPLdreSIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 71989522    721 SENSANIHITVI 732
Cdd:pfam00028   81 LSSTATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2446-2534 4.44e-13

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 67.34  E-value: 4.44e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 2446 SYTLQIPISTPAGESVGQMQAIDEDGGVHGVVKYSIS--DRQSTVKIEEHTGIIRLQKPLvSRRNLTIEQITVVAY--SS 2521
Cdd:cd11304    1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVsgNEDGLFSIDPSTGEITTAKPL-DREEQSSYTLTVTATdgGG 79

                         90
                 ....*....|...
gi 71989522 2522 PTKQSKTTVYLEI 2534
Cdd:cd11304   80 PPLSSTATVTITV 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 256-328 5.09e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 66.60  E-value: 5.09e-13
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 71989522     256 QATDADIGENSRISYDIkkTSAPSNSNFAI-SQSGVITTTASLL--PASTHDVIVVASDHGSPSLSSSAVVTITVL 328
Cdd:smart00112    1 SATDADSGENGKVTYSI--LSGNDDGLFSIdPETGEITTTKPLDreEQPEYTLTVEATDGGGPPLSSTATVTITVL 74
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 461-538 5.90e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 66.22  E-value: 5.90e-13
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522     461 TAKDPDLGQNGWIRYSVL---DTELVSIDKETGRIFVPNTIDCNIGSEIKFRVRAEDGGSPALSTDLQVVADLLDTESKP 537
Cdd:smart00112    1 SATDADSGENGKVTYSILsgnDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 71989522     538 P 538
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2345-2437 7.08e-13

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 66.57  E-value: 7.08e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 2345 VYEVHVLEDTSVGTVLQKIRASNRLGMRNDGLLYSLKE--HQGKLGIDVKTGELTLKTHLDWESEPIISMYLSVSDGNG- 2421
Cdd:cd11304    1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSgnEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGp 80

                         90
                 ....*....|....*..
gi 71989522 2422 -RSAVVPLKIVVEPVDE 2437
Cdd:cd11304   81 pLSSTATVTITVLDVND 97
Cadherin pfam00028
Cadherin domain;
2235-2329 8.66e-13

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 66.17  E-value: 8.66e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522   2235 YYLSLKDSMAHGQKIGQIMASDQDSGENGRVSYRILSGNDLNIVTLNPDTGSIQLNEwndaQLDEFPNATWQILVEARDH 2314
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTK----PLDRESIGEYELTVEATDS 76

                           90
                   ....*....|....*
gi 71989522   2315 GHPARAAVGKVQVSL 2329
Cdd:pfam00028   77 GGPPLSSTATVTITV 91
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1638-1723 9.67e-13

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 66.18  E-value: 9.67e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 1638 VVTIEENVGIEDF-KRILAT----GMTEESRFRFQGNAP--KFSINSTTGSISVL-PLDREASQEHLLIIILTDGG--SR 1707
Cdd:cd11304    3 EVSVPENAPPGTVvLTVSATdpdsGENGEVTYSIVSGNEdgLFSIDPSTGEITTAkPLDREEQSSYTLTVTATDGGgpPL 82

                         90
                 ....*....|....*.
gi 71989522 1708 NDSCTVRVTVADQNDN 1723
Cdd:cd11304   83 SSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1667-1725 1.56e-12

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 65.06  E-value: 1.56e-12
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 71989522    1667 QGNAPKFSINSTTGSISVL-PLDREASQEHLLIIILTDGGSRNDS--CTVRVTVADQNDNKP 1725
Cdd:smart00112   20 GNDDGLFSIDPETGEITTTkPLDREEQPEYTLTVEATDGGGPPLSstATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2254-2330 3.04e-12

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 64.29  E-value: 3.04e-12
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 71989522    2254 ASDQDSGENGRVSYRILSGNDLNIVTLNPDTGSIQLNewndAQLDEFPNATWQILVEARDHGHPARAAVGKVQVSLK 2330
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTT----KPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVL 74
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1051-1136 5.75e-12

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 64.26  E-value: 5.75e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 1051 IVVPAGSPLSTAIGTIVAMDPDKGLNGSVLYR--AQLQSSLFVV-KSNGDVYLRRQLNASDERHQRLSVIVSDQGVPRKS 1127
Cdd:cd11304    4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSivSGNEDGLFSIdPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLS 83


                 ....*....
gi 71989522 1128 VVCHVPVRI 1136
Cdd:cd11304   84 STATVTITV 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2157-2228 5.84e-12

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 63.52  E-value: 5.84e-12
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 71989522    2157 ESREFHYRIQDPEASKIFSIDKF-GRLFVAGPIDREQRATHEFQVEIDNEMMTSQKVQCKCHVIVLDENDNLP 2228
Cdd:smart00112    9 ENGKVTYSILSGNDDGLFSIDPEtGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2034-2120 1.20e-11

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 63.10  E-value: 1.20e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 2034 YQTTVSPATfSPGQPFAKIEAHDLD--ARGALTYSL-GQGSSSIFRVAPESGALFmkVLPP----AGERYLVTVTATDNG 2106
Cdd:cd11304    2 YEVSVPENA-PPGTVVLTVSATDPDsgENGEVTYSIvSGNEDGLFSIDPSTGEIT--TAKPldreEQSSYTLTVTATDGG 78

                         90
                 ....*....|....
gi 71989522 2107 VPSFSTSVPVSVII 2120
Cdd:cd11304   79 GPPLSSTATVTITV 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 563-639 6.13e-11

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 60.83  E-value: 6.13e-11
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522     563 VANNSQCGNSKRIRYSL--QNQDEHLTVDTMSGTVCIQKTFDFEKQKSYQTTVIATNANSE--TSTSLISIRLKDVNDNW 638
Cdd:smart00112    1 SATDADSGENGKVTYSIlsGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPplSSTATVTITVLDVNDNA 80


                    .
gi 71989522     639 P 639
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 29-118 7.02e-11

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 61.18  E-value: 7.02e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522   29 FTVPESAQIGTRIGWISGK---REESAAPKYFVVfpDEQTSKFLKVDERSGEISTIAHLDYEKRSKFDIVaVKVEESGE- 104
Cdd:cd11304    4 VSVPENAPPGTVVLTVSATdpdSGENGEVTYSIV--SGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLT-VTATDGGGp 80

                         90
                 ....*....|....*...
gi 71989522  105 ----TIDILVEVDDENDN 118
Cdd:cd11304   81 plssTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1855-1925 2.36e-10

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 58.90  E-value: 2.36e-10
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 71989522    1855 QPELAGLTYSIVEGNIDSAFSVDSE-GVIRTNLELDREILERYSLKVIGTGSGQQI--GT-RVDVRVNNLNDNVP 1925
Cdd:smart00112    7 SGENGKVTYSILSGNDDGLFSIDPEtGEITTTKPLDREEQPEYTLTVEATDGGGPPlsSTaTVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1356-1428 6.32e-10

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 57.74  E-value: 6.32e-10
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522    1356 TVSD-DSASPISYRFPLLIDN----FSIDQFTGDITLIDTLHWHVTPTYNLIVEAFTSGPG---TTLLVTVNVDDVNDHT 1427
Cdd:smart00112    1 SATDaDSGENGKVTYSILSGNddglFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPplsSTATVTITVLDVNDNA 80


                    .
gi 71989522    1428 P 1428
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1734-1817 7.94e-10

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 58.09  E-value: 7.94e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 1734 ELEIAESSRVGDVLHRFRASDMDIGQNGKFSFELLEDSSGSL-DLVPETGDLVLRRL---SSLQSWKIKLRVVDHGVPGL 1809
Cdd:cd11304    3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLfSIDPSTGEITTAKPldrEEQSSYTLTVTATDGGGPPL 82


                 ....*...
gi 71989522 1810 YVEKNLEI 1817
Cdd:cd11304   83 SSTATVTI 90
Cadherin pfam00028
Cadherin domain;
546-631 9.30e-10

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 57.70  E-value: 9.30e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522    546 QVEIPEDTPIGTCLVKVVANNSQCGNSKRIRYSLQNQDE--HLTVDTMSGTVCIQKTFDFEKQKSYQTTVIATNANSE-- 621
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPggNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPpl 81

                           90
                   ....*....|
gi 71989522    622 TSTSLISIRL 631
Cdd:pfam00028   82 SSTATVTITV 91
Cadherin pfam00028
Cadherin domain;
130-224 2.88e-09

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 56.15  E-value: 2.88e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522    130 EISEFAQLGTSFALPTVTDGDGPKFDVHRFVILQGNVNNVFKLasrkvnEQLQADLVVNGQLDREFRDKYELLIEAQDGG 209
Cdd:pfam00028    4 SVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRI------DPDTGDISTTKPLDRESIGEYELTVEATDSG 77

                           90
                   ....*....|....*
gi 71989522    210 KPAKIGQLRCSIEII 224
Cdd:pfam00028   78 GPPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
459-531 4.47e-09

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 55.77  E-value: 4.47e-09
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 71989522    459 TLTAKDPDLGQNGWIRYSVLDTE---LVSIDKETGRIFVPNTIDCNIGSEIKFRVRAEDGGSPALSTDLQVVADLL 531
Cdd:pfam00028   17 TVTATDPDLGPNGRIFYSILGGGpggNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
1338-1420 1.53e-08

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 54.23  E-value: 1.53e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522   1338 VNIREDTPTGSIITTVNATVSDDSA-SPISYRF--PLLIDNFSIDQFTGDITLIDTLHWHVTPTYNLIVEAFTSGPG--- 1411
Cdd:pfam00028    3 ASVPENAPVGTEVLTVTATDPDLGPnGRIFYSIlgGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPpls 82


                   ....*....
gi 71989522   1412 TTLLVTVNV 1420
Cdd:pfam00028   83 STATVTITV 91
Cadherin pfam00028
Cadherin domain;
2447-2534 3.86e-08

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 53.07  E-value: 3.86e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522   2447 YTLQIPISTPAGESVGQMQAIDEDGGVHGVVKYSIS--DRQSTVKIEEHTGIIRLQKPLvSRRNLTIEQITVVA--YSSP 2522
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILggGPGGNFRIDPDTGDISTTKPL-DRESIGEYELTVEAtdSGGP 79

                           90
                   ....*....|..
gi 71989522   2523 TKQSKTTVYLEI 2534
Cdd:pfam00028   80 PLSSTATVTITV 91
Cadherin pfam00028
Cadherin domain;
1837-1908 4.42e-08

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 53.07  E-value: 4.42e-08
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 71989522   1837 YLSTIDEGLPRGQFIAKLQ------PELAGLTYSIVEGNIDSAFSVDSE-GVIRTNLELDREILERYSLKVIGTGSGQQ 1908
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTatdpdlGPNGRIFYSILGGGPGGNFRIDPDtGDISTTKPLDRESIGEYELTVEATDSGGP 79
Cadherin pfam00028
Cadherin domain;
746-828 7.71e-08

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 52.30  E-value: 7.71e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522    746 YEIRTTEDILPGIAIGSVGAM-------SKVKYSIYSGDQDHNFSIDEDTGKIYVTRYLDADVHDTVLLNIQATLPSGE- 817
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATdpdlgpnGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPp 80

                           90
                   ....*....|..
gi 71989522    818 -SNQTQVVIFIE 828
Cdd:pfam00028   81 lSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
1050-1136 8.02e-08

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 52.30  E-value: 8.02e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522   1050 PIVVPAGSPLSTAIGTIVAMDPDKGLNGSVLYRAQLQSS---LFVVKSNGDVYLRRQLNASDERHQRLSVIVSDQGVPRK 1126
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPggnFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPL 81

                           90
                   ....*....|
gi 71989522   1127 SVVCHVPVRI 1136
Cdd:pfam00028   82 SSTATVTITV 91
Cadherin pfam00028
Cadherin domain;
1667-1717 1.72e-07

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 51.15  E-value: 1.72e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 71989522   1667 QGNAPKFSINSTTGSISVL-PLDREASQEHLLIIILTDGGSRNDSCTVRVTV 1717
Cdd:pfam00028   38 GGPGGNFRIDPDTGDISTTkPLDRESIGEYELTVEATDSGGPPLSSTATVTI 89
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 57-120 2.36e-07

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 50.43  E-value: 2.36e-07
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 71989522      57 FVVFPDEQTSKFlKVDERSGEISTIAHLDYEKRSKFDIVaVKVEESGE-----TIDILVEVDDENDNAP 120
Cdd:smart00112   15 YSILSGNDDGLF-SIDPETGEITTTKPLDREEQPEYTLT-VEATDGGGpplssTATVTITVLDVNDNAP 81
Cadherin pfam00028
Cadherin domain;
1736-1818 1.62e-06

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 48.45  E-value: 1.62e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522   1736 EIAESSRVGDVLHRFRASDMDIGQNGKFSFELLED-SSGSLDLVPETGDL-VLRRLS--SLQSWKIKLRVVDHGVPGLYV 1811
Cdd:pfam00028    4 SVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGgPGGNFRIDPDTGDIsTTKPLDreSIGEYELTVEATDSGGPPLSS 83


                   ....*..
gi 71989522   1812 EKNLEIS 1818
Cdd:pfam00028   84 TATVTIT 90
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2054-2120 2.88e-06

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 47.34  E-value: 2.88e-06
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 71989522    2054 AHDLD--ARGALTYSLGQGS-SSIFRVAPESGALFmkVLPP----AGERYLVTVTATDNGVPSFSTSVPVSVII 2120
Cdd:smart00112    2 ATDADsgENGKVTYSILSGNdDGLFSIDPETGEIT--TTKPldreEQPEYTLTVEATDGGGPPLSSTATVTITV 73
Cadherin pfam00028
Cadherin domain;
2346-2433 3.34e-06

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 47.68  E-value: 3.34e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522   2346 YEVHVLEDTSVGTVLQKIRASNRLGMRNDGLLYSLKEH--QGKLGIDVKTGELTLKTHLDWESEPIISMYLSVSD--GNG 2421
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGgpGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDsgGPP 80

                           90
                   ....*....|..
gi 71989522   2422 RSAVVPLKIVVE 2433
Cdd:pfam00028   81 LSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
2136-2201 3.98e-06

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 47.30  E-value: 3.98e-06
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 71989522   2136 FRFEVMENSKIGLQIGNL------SGEESReFHYRIQDPEASKIFSIDKF-GRLFVAGPIDREQRATHEFQVE 2201
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVtatdpdLGPNGR-IFYSILGGGPGGNFRIDPDtGDISTTKPLDRESIGEYELTVE 72
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2465-2534 2.39e-05

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 44.65  E-value: 2.39e-05
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 71989522    2465 QAIDEDGGVHGVVKYSISD--RQSTVKIEEHTGIIRLQKPLvSRRNLTIEQITVVAYSSPTKQSKTTVYLEI 2534
Cdd:smart00112    1 SATDADSGENGKVTYSILSgnDDGLFSIDPETGEITTTKPL-DREEQPEYTLTVEATDGGGPPLSSTATVTI 71
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1445-1515 4.58e-05

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 44.61  E-value: 4.58e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 71989522 1445 GGMVHRVVAIDLDKDP--EIRYSLKyagSEVAKEFFKIDEKSGEIFVVESSSALSTSFggaglpETLTIRATD 1515
Cdd:cd11304   13 GTVVLTVSATDPDSGEngEVTYSIV---SGNEDGLFSIDPSTGEITTAKPLDREEQSS------YTLTVTATD 76
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1067-1136 7.73e-05

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 43.49  E-value: 7.73e-05
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 71989522    1067 VAMDPDKGLNGSVLYR--AQLQSSLFVV-KSNGDVYLRRQLNASDERHQRLSVIVSDQGVPRKSVVCHVPVRI 1136
Cdd:smart00112    1 SATDADSGENGKVTYSilSGNDDGLFSIdPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITV 73
Cadherin pfam00028
Cadherin domain;
29-97 2.26e-04

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 42.29  E-value: 2.26e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 71989522     29 FTVPESAQIGTRIGWISGK---REESAAPKYFVVFPDEqtSKFLKVDERSGEISTIAHLDYEKRSKFDIVAV 97
Cdd:pfam00028    3 ASVPENAPVGTEVLTVTATdpdLGPNGRIFYSILGGGP--GGNFRIDPDTGDISTTKPLDRESIGEYELTVE 72
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2373-2440 2.48e-04

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 41.95  E-value: 2.48e-04
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 71989522    2373 NDGLLYSLK--EHQGKLGIDVKTGELTLKTHLDWESEPIISMYLSVSDGNG--RSAVVPLKIVVEPVDEFAP 2440
Cdd:smart00112   10 NGKVTYSILsgNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGppLSSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1751-1817 2.58e-03

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 38.87  E-value: 2.58e-03
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 71989522    1751 RASDMDIGQNGKFSFELLEDSSGSL-DLVPETGDLVLRRL---SSLQSWKIKLRVVDHGVPGLYVEKNLEI 1817
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLfSIDPETGEITTTKPldrEEQPEYTLTVEATDGGGPPLSSTATVTI 71
Cadherin pfam00028
Cadherin domain;
1434-1517 4.45e-03

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 38.82  E-value: 4.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522   1434 PTVLLPSSYRKGGMVHRVVAIDLDKDPE--IRYSLKYAGSEvakEFFKIDEKSGEIFVVESSSALSTSFggaglpETLTI 1511
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNgrIFYSILGGGPG---GNFRIDPDTGDISTTKPLDRESIGE------YELTV 71


                   ....*.
gi 71989522   1512 RATDLQ 1517
Cdd:pfam00028   72 EATDSG 77
 
Name Accession Description Interval E-value
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 947-1041 8.25e-32

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 120.88  E-value: 8.25e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522  947 YTMEVLENSPPKTIVGKVVARDKDSLENGQIVYRITNGSE--YFGIDEKLGNVYTKRSIDREVISHVDISIVAEDKGVPP 1024
Cdd:cd11304    2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEdgLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPP 81

                         90
                 ....*....|....*..
gi 71989522 1025 RSSTASARISVLDVNDN 1041
Cdd:cd11304   82 LSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 843-938 1.39e-29

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 114.33  E-value: 1.39e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522  843 EISIREDLKLHEPFYVVQASDKDKKKNGEVRYSIISSHPGSSIEIDQFTGQLSTGSLLDYEATRNYKLRVKATDLGIPPR 922
Cdd:cd11304    3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPL 82

                         90
                 ....*....|....*.
gi 71989522  923 SSNMTLFIHVLDVNDN 938
Cdd:cd11304   83 SSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 860-940 3.31e-25

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 101.27  E-value: 3.31e-25
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522     860 QASDKDKKKNGEVRYSIISSHPGSSIEIDQFTGQLSTGSLLDYEATRNYKLRVKATDLGIPPRSSNMTLFIHVLDVNDNA 939
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 71989522     940 P 940
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1934-2025 6.05e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 98.15  E-value: 6.05e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 1934 RVPENLRVGSYVATVGAKDVD--NLAPLRYFLVSDSSGQtptHFNIDQFTGTIHLTAPLDFEVLPEHTLTIKATDG---S 2008
Cdd:cd11304    5 SVPENAPPGTVVLTVSATDPDsgENGEVTYSIVSGNEDG---LFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGggpP 81

                         90
                 ....*....|....*..
gi 71989522 2009 FDTFTNLTIFVSDINDN 2025
Cdd:cd11304   82 LSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 965-1043 1.11e-22

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 93.95  E-value: 1.11e-22
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522     965 VARDKDSLENGQIVYRITNGSE--YFGIDEKLGNVYTKRSIDREVISHVDISIVAEDKGVPPRSSTASARISVLDVNDNP 1042
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDdgLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 71989522    1043 P 1043
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 645-733 2.46e-22

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 93.53  E-value: 2.46e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522  645 EYHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHILSESSS--FSINPVTGEVFAQKPL---ARGRFHLVVSAKDGGGQ 719
Cdd:cd11304    1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDglFSIDPSTGEITTAKPLdreEQSSYTLTVTATDGGGP 80

                         90
                 ....*....|....
gi 71989522  720 SSENSANIHITVID 733
Cdd:cd11304   81 PLSSTATVTITVLD 94
Cadherin pfam00028
Cadherin domain;
947-1036 5.53e-22

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 92.36  E-value: 5.53e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522    947 YTMEVLENSPPKTIVGKVVARDKDSLENGQIVYRITNGSEY--FGIDEKLGNVYTKRSIDREVISHVDISIVAEDKGVPP 1024
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGgnFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 71989522   1025 RSSTASARISVL 1036
Cdd:pfam00028   81 LSSTATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 238-328 1.22e-21

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 91.61  E-value: 1.22e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522  238 YTASVSANISIGSHLITVQATDADIGENSRISYDIkkTSAPSNSNFAI-SQSGVITTTASL--LPASTHDVIVVASDHGS 314
Cdd:cd11304    2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSI--VSGNEDGLFSIdPSTGEITTAKPLdrEEQSSYTLTVTATDGGG 79

                         90
                 ....*....|....
gi 71989522  315 PSLSSSAVVTITVL 328
Cdd:cd11304   80 PPLSSTATVTITVL 93
Cadherin pfam00028
Cadherin domain;
843-933 4.64e-19

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 84.27  E-value: 4.64e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522    843 EISIREDLKLHEPFYVVQASDKDKKKNGEVRYSIISSHPGSSIEIDQFTGQLSTGSLLDYEATRNYKLRVKATDLGIPPR 922
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPL 81

                           90
                   ....*....|.
gi 71989522    923 SSNMTLFIHVL 933
Cdd:pfam00028   82 SSTATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2235-2330 6.66e-19

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 83.90  E-value: 6.66e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 2235 YYLSLKDSMAHGQKIGQIMASDQDSGENGRVSYRILSGNDLNIVTLNPDTGSIQLNEwndaQLDEFPNATWQILVEARDH 2314
Cdd:cd11304    2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAK----PLDREEQSSYTLTVTATDG 77

                         90
                 ....*....|....*.
gi 71989522 2315 GHPARAAVGKVQVSLK 2330
Cdd:cd11304   78 GGPPLSSTATVTITVL 93
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 546-637 1.15e-18

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 83.13  E-value: 1.15e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522  546 QVEIPEDTPIGTCLVKVVANNSQCGNSKRIRYSL--QNQDEHLTVDTMSGTVCIQKTFDFEKQKSYQTTVIATNANSE-- 621
Cdd:cd11304    3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIvsGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPpl 82

                         90
                 ....*....|....*.
gi 71989522  622 TSTSLISIRLKDVNDN 637
Cdd:cd11304   83 SSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1951-2027 1.19e-16

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 77.00  E-value: 1.19e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522    1951 KDVDNLAPLRYFLVSDSSGQtptHFNIDQFTGTIHLTAPLDFEVLPEHTLTIKATDG---SFDTFTNLTIFVSDINDNAP 2027
Cdd:smart00112    5 ADSGENGKVTYSILSGNDDG---LFSIDPETGEITTTKPLDREEQPEYTLTVEATDGggpPLSSTATVTITVLDVNDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 129-229 1.27e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 77.35  E-value: 1.27e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522  129 LEISEFAQLGTSFALPTVTDGDGPKFDVHRFVILQGNVNNVFKLasrkvnEQLQADLVVNGQLDREFRDKYELLIEAQDG 208
Cdd:cd11304    4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSI------DPSTGEITTAKPLDREEQSSYTLTVTATDG 77

                         90       100
                 ....*....|....*....|.
gi 71989522  209 GKPAKIGQLRCSIEIIDANDN 229
Cdd:cd11304   78 GGPPLSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
238-328 1.35e-16

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 76.96  E-value: 1.35e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522    238 YTASVSANISIGSHLITVQATDADIGENSRISYDIKKTsaPSNSNFAISQ-SGVITTTASL--LPASTHDVIVVASDHGS 314
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGG--GPGGNFRIDPdTGDISTTKPLdrESIGEYELTVEATDSGG 78

                           90
                   ....*....|....
gi 71989522    315 PSLSSSAVVTITVL 328
Cdd:pfam00028   79 PPLSSTATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1337-1426 5.87e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 75.43  E-value: 5.87e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 1337 RVNIREDTPTGSIITTVNATVSDDSA-SPISYRF--PLLIDNFSIDQFTGDITLIDTLHWHVTPTYNLIVEAFTSGPG-- 1411
Cdd:cd11304    3 EVSVPENAPPGTVVLTVSATDPDSGEnGEVTYSIvsGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPpl 82

                         90
                 ....*....|....*.
gi 71989522 1412 -TTLLVTVNVDDVNDH 1426
Cdd:cd11304   83 sSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 746-833 7.71e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 75.04  E-value: 7.71e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522  746 YEIRTTEDILPGIAIGSVGAM-------SKVKYSIYSGDQDHNFSIDEDTGKIYVTRYLDADVHDTVLLNIQAT--LPSG 816
Cdd:cd11304    2 YEVSVPENAPPGTVVLTVSATdpdsgenGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATdgGGPP 81

                         90
                 ....*....|....*..
gi 71989522  817 ESNQTQVVIFIEDHNDN 833
Cdd:cd11304   82 LSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2135-2226 9.27e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 75.04  E-value: 9.27e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 2135 EFRFEVMENSKIGLQIGNLS-----GEESREFHYRIQDPEASKIFSID-KFGRLFVAGPIDREQRATHEFQVEIDNEMMT 2208
Cdd:cd11304    1 SYEVSVPENAPPGTVVLTVSatdpdSGENGEVTYSIVSGNEDGLFSIDpSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                         90
                 ....*....|....*...
gi 71989522 2209 SQKVQCKCHVIVLDENDN 2226
Cdd:cd11304   81 PLSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 664-735 3.46e-15

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 72.77  E-value: 3.46e-15
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 71989522     664 SASDMDSGTFGEVSYHILSES--SSFSINPVTGEVFAQKPL---ARGRFHLVVSAKDGGGQSSENSANIHITVIDKD 735
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNddGLFSIDPETGEITTTKPLdreEQPEYTLTVEATDGGGPPLSSTATVTITVLDVN 77
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1836-1923 1.75e-14

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 71.19  E-value: 1.75e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 1836 TYLSTIDEGLPRGQFIAKLQ------PELAGLTYSIVEGNIDSAFSVDSE-GVIRTNLELDREILERYSLKVIGT--GSG 1906
Cdd:cd11304    1 SYEVSVPENAPPGTVVLTVSatdpdsGENGEVTYSIVSGNEDGLFSIDPStGEITTAKPLDREEQSSYTLTVTATdgGGP 80

                         90
                 ....*....|....*...
gi 71989522 1907 QQIGT-RVDVRVNNLNDN 1923
Cdd:cd11304   81 PLSSTaTVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 145-231 2.27e-14

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 70.46  E-value: 2.27e-14
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522     145 TVTDGDGPKFDVHRFVILQGNVNNVFKLasrkvnEQLQADLVVNGQLDREFRDKYELLIEAQDGGKPAKIGQLRCSIEII 224
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSI------DPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVL 74


                    ....*..
gi 71989522     225 DANDNAP 231
Cdd:smart00112   75 DVNDNAP 81
Cadherin pfam00028
Cadherin domain;
1934-2019 4.39e-14

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 70.02  E-value: 4.39e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522   1934 RVPENLRVGSYVATVGAKDVDnLAP---LRYFLVSDSSGQtptHFNIDQFTGTIHLTAPLDFEVLPEHTLTIKATDGSF- 2009
Cdd:pfam00028    4 SVPENAPVGTEVLTVTATDPD-LGPngrIFYSILGGGPGG---NFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGp 79

                           90
                   ....*....|..
gi 71989522   2010 --DTFTNLTIFV 2019
Cdd:pfam00028   80 plSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 764-835 1.34e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 68.15  E-value: 1.34e-13
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 71989522     764 GAMSKVKYSIYSGDQDHNFSIDEDTGKIYVTRYLDADVHDTVLLNIQATLPSGE--SNQTQVVIFIEDHNDNPP 835
Cdd:smart00112    8 GENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPplSSTATVTITVLDVNDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 459-532 3.01e-13

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 67.72  E-value: 3.01e-13
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 71989522  459 TLTAKDPDLGQNGWIRYSVL---DTELVSIDKETGRIFVPNTIDCNIGSEIKFRVRAEDGGSPALSTDLQVVADLLD 532
Cdd:cd11304   18 TVSATDPDSGENGEVTYSIVsgnEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLSSTATVTITVLD 94
Cadherin pfam00028
Cadherin domain;
646-732 3.46e-13

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 67.33  E-value: 3.46e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522    646 YHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHILSESSS--FSINPVTGEVFAQKPL---ARGRFHLVVSAKDGGGQS 720
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGgnFRIDPDTGDISTTKPLdreSIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 71989522    721 SENSANIHITVI 732
Cdd:pfam00028   81 LSSTATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2446-2534 4.44e-13

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 67.34  E-value: 4.44e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 2446 SYTLQIPISTPAGESVGQMQAIDEDGGVHGVVKYSIS--DRQSTVKIEEHTGIIRLQKPLvSRRNLTIEQITVVAY--SS 2521
Cdd:cd11304    1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVsgNEDGLFSIDPSTGEITTAKPL-DREEQSSYTLTVTATdgGG 79

                         90
                 ....*....|...
gi 71989522 2522 PTKQSKTTVYLEI 2534
Cdd:cd11304   80 PPLSSTATVTITV 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 256-328 5.09e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 66.60  E-value: 5.09e-13
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 71989522     256 QATDADIGENSRISYDIkkTSAPSNSNFAI-SQSGVITTTASLL--PASTHDVIVVASDHGSPSLSSSAVVTITVL 328
Cdd:smart00112    1 SATDADSGENGKVTYSI--LSGNDDGLFSIdPETGEITTTKPLDreEQPEYTLTVEATDGGGPPLSSTATVTITVL 74
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 461-538 5.90e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 66.22  E-value: 5.90e-13
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522     461 TAKDPDLGQNGWIRYSVL---DTELVSIDKETGRIFVPNTIDCNIGSEIKFRVRAEDGGSPALSTDLQVVADLLDTESKP 537
Cdd:smart00112    1 SATDADSGENGKVTYSILsgnDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 71989522     538 P 538
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2345-2437 7.08e-13

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 66.57  E-value: 7.08e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 2345 VYEVHVLEDTSVGTVLQKIRASNRLGMRNDGLLYSLKE--HQGKLGIDVKTGELTLKTHLDWESEPIISMYLSVSDGNG- 2421
Cdd:cd11304    1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSgnEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGp 80

                         90
                 ....*....|....*..
gi 71989522 2422 -RSAVVPLKIVVEPVDE 2437
Cdd:cd11304   81 pLSSTATVTITVLDVND 97
Cadherin pfam00028
Cadherin domain;
2235-2329 8.66e-13

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 66.17  E-value: 8.66e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522   2235 YYLSLKDSMAHGQKIGQIMASDQDSGENGRVSYRILSGNDLNIVTLNPDTGSIQLNEwndaQLDEFPNATWQILVEARDH 2314
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTK----PLDRESIGEYELTVEATDS 76

                           90
                   ....*....|....*
gi 71989522   2315 GHPARAAVGKVQVSL 2329
Cdd:pfam00028   77 GGPPLSSTATVTITV 91
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1638-1723 9.67e-13

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 66.18  E-value: 9.67e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 1638 VVTIEENVGIEDF-KRILAT----GMTEESRFRFQGNAP--KFSINSTTGSISVL-PLDREASQEHLLIIILTDGG--SR 1707
Cdd:cd11304    3 EVSVPENAPPGTVvLTVSATdpdsGENGEVTYSIVSGNEdgLFSIDPSTGEITTAkPLDREEQSSYTLTVTATDGGgpPL 82

                         90
                 ....*....|....*.
gi 71989522 1708 NDSCTVRVTVADQNDN 1723
Cdd:cd11304   83 SSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1667-1725 1.56e-12

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 65.06  E-value: 1.56e-12
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 71989522    1667 QGNAPKFSINSTTGSISVL-PLDREASQEHLLIIILTDGGSRNDS--CTVRVTVADQNDNKP 1725
Cdd:smart00112   20 GNDDGLFSIDPETGEITTTkPLDREEQPEYTLTVEATDGGGPPLSstATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2254-2330 3.04e-12

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 64.29  E-value: 3.04e-12
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 71989522    2254 ASDQDSGENGRVSYRILSGNDLNIVTLNPDTGSIQLNewndAQLDEFPNATWQILVEARDHGHPARAAVGKVQVSLK 2330
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTT----KPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVL 74
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1051-1136 5.75e-12

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 64.26  E-value: 5.75e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 1051 IVVPAGSPLSTAIGTIVAMDPDKGLNGSVLYR--AQLQSSLFVV-KSNGDVYLRRQLNASDERHQRLSVIVSDQGVPRKS 1127
Cdd:cd11304    4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSivSGNEDGLFSIdPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLS 83


                 ....*....
gi 71989522 1128 VVCHVPVRI 1136
Cdd:cd11304   84 STATVTITV 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2157-2228 5.84e-12

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 63.52  E-value: 5.84e-12
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 71989522    2157 ESREFHYRIQDPEASKIFSIDKF-GRLFVAGPIDREQRATHEFQVEIDNEMMTSQKVQCKCHVIVLDENDNLP 2228
Cdd:smart00112    9 ENGKVTYSILSGNDDGLFSIDPEtGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2034-2120 1.20e-11

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 63.10  E-value: 1.20e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 2034 YQTTVSPATfSPGQPFAKIEAHDLD--ARGALTYSL-GQGSSSIFRVAPESGALFmkVLPP----AGERYLVTVTATDNG 2106
Cdd:cd11304    2 YEVSVPENA-PPGTVVLTVSATDPDsgENGEVTYSIvSGNEDGLFSIDPSTGEIT--TAKPldreEQSSYTLTVTATDGG 78

                         90
                 ....*....|....
gi 71989522 2107 VPSFSTSVPVSVII 2120
Cdd:cd11304   79 GPPLSSTATVTITV 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 563-639 6.13e-11

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 60.83  E-value: 6.13e-11
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522     563 VANNSQCGNSKRIRYSL--QNQDEHLTVDTMSGTVCIQKTFDFEKQKSYQTTVIATNANSE--TSTSLISIRLKDVNDNW 638
Cdd:smart00112    1 SATDADSGENGKVTYSIlsGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPplSSTATVTITVLDVNDNA 80


                    .
gi 71989522     639 P 639
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 29-118 7.02e-11

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 61.18  E-value: 7.02e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522   29 FTVPESAQIGTRIGWISGK---REESAAPKYFVVfpDEQTSKFLKVDERSGEISTIAHLDYEKRSKFDIVaVKVEESGE- 104
Cdd:cd11304    4 VSVPENAPPGTVVLTVSATdpdSGENGEVTYSIV--SGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLT-VTATDGGGp 80

                         90
                 ....*....|....*...
gi 71989522  105 ----TIDILVEVDDENDN 118
Cdd:cd11304   81 plssTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1855-1925 2.36e-10

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 58.90  E-value: 2.36e-10
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 71989522    1855 QPELAGLTYSIVEGNIDSAFSVDSE-GVIRTNLELDREILERYSLKVIGTGSGQQI--GT-RVDVRVNNLNDNVP 1925
Cdd:smart00112    7 SGENGKVTYSILSGNDDGLFSIDPEtGEITTTKPLDREEQPEYTLTVEATDGGGPPlsSTaTVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1356-1428 6.32e-10

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 57.74  E-value: 6.32e-10
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522    1356 TVSD-DSASPISYRFPLLIDN----FSIDQFTGDITLIDTLHWHVTPTYNLIVEAFTSGPG---TTLLVTVNVDDVNDHT 1427
Cdd:smart00112    1 SATDaDSGENGKVTYSILSGNddglFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPplsSTATVTITVLDVNDNA 80


                    .
gi 71989522    1428 P 1428
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1734-1817 7.94e-10

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 58.09  E-value: 7.94e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522 1734 ELEIAESSRVGDVLHRFRASDMDIGQNGKFSFELLEDSSGSL-DLVPETGDLVLRRL---SSLQSWKIKLRVVDHGVPGL 1809
Cdd:cd11304    3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLfSIDPSTGEITTAKPldrEEQSSYTLTVTATDGGGPPL 82


                 ....*...
gi 71989522 1810 YVEKNLEI 1817
Cdd:cd11304   83 SSTATVTI 90
Cadherin pfam00028
Cadherin domain;
546-631 9.30e-10

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 57.70  E-value: 9.30e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522    546 QVEIPEDTPIGTCLVKVVANNSQCGNSKRIRYSLQNQDE--HLTVDTMSGTVCIQKTFDFEKQKSYQTTVIATNANSE-- 621
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPggNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPpl 81

                           90
                   ....*....|
gi 71989522    622 TSTSLISIRL 631
Cdd:pfam00028   82 SSTATVTITV 91
Cadherin pfam00028
Cadherin domain;
130-224 2.88e-09

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 56.15  E-value: 2.88e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522    130 EISEFAQLGTSFALPTVTDGDGPKFDVHRFVILQGNVNNVFKLasrkvnEQLQADLVVNGQLDREFRDKYELLIEAQDGG 209
Cdd:pfam00028    4 SVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRI------DPDTGDISTTKPLDRESIGEYELTVEATDSG 77

                           90
                   ....*....|....*
gi 71989522    210 KPAKIGQLRCSIEII 224
Cdd:pfam00028   78 GPPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
459-531 4.47e-09

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 55.77  E-value: 4.47e-09
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 71989522    459 TLTAKDPDLGQNGWIRYSVLDTE---LVSIDKETGRIFVPNTIDCNIGSEIKFRVRAEDGGSPALSTDLQVVADLL 531
Cdd:pfam00028   17 TVTATDPDLGPNGRIFYSILGGGpggNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
1338-1420 1.53e-08

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 54.23  E-value: 1.53e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522   1338 VNIREDTPTGSIITTVNATVSDDSA-SPISYRF--PLLIDNFSIDQFTGDITLIDTLHWHVTPTYNLIVEAFTSGPG--- 1411
Cdd:pfam00028    3 ASVPENAPVGTEVLTVTATDPDLGPnGRIFYSIlgGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPpls 82


                   ....*....
gi 71989522   1412 TTLLVTVNV 1420
Cdd:pfam00028   83 STATVTITV 91
Cadherin pfam00028
Cadherin domain;
2447-2534 3.86e-08

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 53.07  E-value: 3.86e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522   2447 YTLQIPISTPAGESVGQMQAIDEDGGVHGVVKYSIS--DRQSTVKIEEHTGIIRLQKPLvSRRNLTIEQITVVA--YSSP 2522
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILggGPGGNFRIDPDTGDISTTKPL-DRESIGEYELTVEAtdSGGP 79

                           90
                   ....*....|..
gi 71989522   2523 TKQSKTTVYLEI 2534
Cdd:pfam00028   80 PLSSTATVTITV 91
Cadherin pfam00028
Cadherin domain;
1837-1908 4.42e-08

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 53.07  E-value: 4.42e-08
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 71989522   1837 YLSTIDEGLPRGQFIAKLQ------PELAGLTYSIVEGNIDSAFSVDSE-GVIRTNLELDREILERYSLKVIGTGSGQQ 1908
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTatdpdlGPNGRIFYSILGGGPGGNFRIDPDtGDISTTKPLDRESIGEYELTVEATDSGGP 79
Cadherin pfam00028
Cadherin domain;
746-828 7.71e-08

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 52.30  E-value: 7.71e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522    746 YEIRTTEDILPGIAIGSVGAM-------SKVKYSIYSGDQDHNFSIDEDTGKIYVTRYLDADVHDTVLLNIQATLPSGE- 817
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATdpdlgpnGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPp 80

                           90
                   ....*....|..
gi 71989522    818 -SNQTQVVIFIE 828
Cdd:pfam00028   81 lSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
1050-1136 8.02e-08

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 52.30  E-value: 8.02e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522   1050 PIVVPAGSPLSTAIGTIVAMDPDKGLNGSVLYRAQLQSS---LFVVKSNGDVYLRRQLNASDERHQRLSVIVSDQGVPRK 1126
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPggnFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPL 81

                           90
                   ....*....|
gi 71989522   1127 SVVCHVPVRI 1136
Cdd:pfam00028   82 SSTATVTITV 91
Cadherin pfam00028
Cadherin domain;
1667-1717 1.72e-07

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 51.15  E-value: 1.72e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 71989522   1667 QGNAPKFSINSTTGSISVL-PLDREASQEHLLIIILTDGGSRNDSCTVRVTV 1717
Cdd:pfam00028   38 GGPGGNFRIDPDTGDISTTkPLDRESIGEYELTVEATDSGGPPLSSTATVTI 89
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 57-120 2.36e-07

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 50.43  E-value: 2.36e-07
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 71989522      57 FVVFPDEQTSKFlKVDERSGEISTIAHLDYEKRSKFDIVaVKVEESGE-----TIDILVEVDDENDNAP 120
Cdd:smart00112   15 YSILSGNDDGLF-SIDPETGEITTTKPLDREEQPEYTLT-VEATDGGGpplssTATVTITVLDVNDNAP 81
Cadherin pfam00028
Cadherin domain;
1736-1818 1.62e-06

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 48.45  E-value: 1.62e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522   1736 EIAESSRVGDVLHRFRASDMDIGQNGKFSFELLED-SSGSLDLVPETGDL-VLRRLS--SLQSWKIKLRVVDHGVPGLYV 1811
Cdd:pfam00028    4 SVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGgPGGNFRIDPDTGDIsTTKPLDreSIGEYELTVEATDSGGPPLSS 83


                   ....*..
gi 71989522   1812 EKNLEIS 1818
Cdd:pfam00028   84 TATVTIT 90
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2054-2120 2.88e-06

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 47.34  E-value: 2.88e-06
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 71989522    2054 AHDLD--ARGALTYSLGQGS-SSIFRVAPESGALFmkVLPP----AGERYLVTVTATDNGVPSFSTSVPVSVII 2120
Cdd:smart00112    2 ATDADsgENGKVTYSILSGNdDGLFSIDPETGEIT--TTKPldreEQPEYTLTVEATDGGGPPLSSTATVTITV 73
Cadherin pfam00028
Cadherin domain;
2346-2433 3.34e-06

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 47.68  E-value: 3.34e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522   2346 YEVHVLEDTSVGTVLQKIRASNRLGMRNDGLLYSLKEH--QGKLGIDVKTGELTLKTHLDWESEPIISMYLSVSD--GNG 2421
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGgpGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDsgGPP 80

                           90
                   ....*....|..
gi 71989522   2422 RSAVVPLKIVVE 2433
Cdd:pfam00028   81 LSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
2136-2201 3.98e-06

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 47.30  E-value: 3.98e-06
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 71989522   2136 FRFEVMENSKIGLQIGNL------SGEESReFHYRIQDPEASKIFSIDKF-GRLFVAGPIDREQRATHEFQVE 2201
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVtatdpdLGPNGR-IFYSILGGGPGGNFRIDPDtGDISTTKPLDRESIGEYELTVE 72
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2465-2534 2.39e-05

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 44.65  E-value: 2.39e-05
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 71989522    2465 QAIDEDGGVHGVVKYSISD--RQSTVKIEEHTGIIRLQKPLvSRRNLTIEQITVVAYSSPTKQSKTTVYLEI 2534
Cdd:smart00112    1 SATDADSGENGKVTYSILSgnDDGLFSIDPETGEITTTKPL-DREEQPEYTLTVEATDGGGPPLSSTATVTI 71
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1445-1515 4.58e-05

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 44.61  E-value: 4.58e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 71989522 1445 GGMVHRVVAIDLDKDP--EIRYSLKyagSEVAKEFFKIDEKSGEIFVVESSSALSTSFggaglpETLTIRATD 1515
Cdd:cd11304   13 GTVVLTVSATDPDSGEngEVTYSIV---SGNEDGLFSIDPSTGEITTAKPLDREEQSS------YTLTVTATD 76
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1067-1136 7.73e-05

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 43.49  E-value: 7.73e-05
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 71989522    1067 VAMDPDKGLNGSVLYR--AQLQSSLFVV-KSNGDVYLRRQLNASDERHQRLSVIVSDQGVPRKSVVCHVPVRI 1136
Cdd:smart00112    1 SATDADSGENGKVTYSilSGNDDGLFSIdPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITV 73
Cadherin pfam00028
Cadherin domain;
29-97 2.26e-04

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 42.29  E-value: 2.26e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 71989522     29 FTVPESAQIGTRIGWISGK---REESAAPKYFVVFPDEqtSKFLKVDERSGEISTIAHLDYEKRSKFDIVAV 97
Cdd:pfam00028    3 ASVPENAPVGTEVLTVTATdpdLGPNGRIFYSILGGGP--GGNFRIDPDTGDISTTKPLDRESIGEYELTVE 72
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2373-2440 2.48e-04

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 41.95  E-value: 2.48e-04
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 71989522    2373 NDGLLYSLK--EHQGKLGIDVKTGELTLKTHLDWESEPIISMYLSVSDGNG--RSAVVPLKIVVEPVDEFAP 2440
Cdd:smart00112   10 NGKVTYSILsgNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGppLSSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1751-1817 2.58e-03

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 38.87  E-value: 2.58e-03
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 71989522    1751 RASDMDIGQNGKFSFELLEDSSGSL-DLVPETGDLVLRRL---SSLQSWKIKLRVVDHGVPGLYVEKNLEI 1817
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLfSIDPETGEITTTKPldrEEQPEYTLTVEATDGGGPPLSSTATVTI 71
Cadherin pfam00028
Cadherin domain;
1434-1517 4.45e-03

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 38.82  E-value: 4.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989522   1434 PTVLLPSSYRKGGMVHRVVAIDLDKDPE--IRYSLKYAGSEvakEFFKIDEKSGEIFVVESSSALSTSFggaglpETLTI 1511
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNgrIFYSILGGGPG---GNFRIDPDTGDISTTKPLDRESIGE------YELTV 71


                   ....*.
gi 71989522   1512 RATDLQ 1517
Cdd:pfam00028   72 EATDSG 77
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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