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Conserved domains on  [gi|17533223|ref|NP_496654|]
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F-box domain-containing protein [Caenorhabditis elegans]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FBOX smart00256
A Receptor for Ubiquitination Targets;
14-44 3.10e-04

A Receptor for Ubiquitination Targets;


:

Pssm-ID: 197608  Cd Length: 41  Bit Score: 37.42  E-value: 3.10e-04
                           10        20        30
                   ....*....|....*....|....*....|.
gi 17533223     14 LPTVVISEVLNHLKNIDICILRTTSRKIRTI 44
Cdd:smart00256   1 LPDEILEEILSKLDPKDLLRLRKVSRKWRSL 31
HU-CCDC81_bac_2 super family cl40293
CCDC81-like prokaryotic HU domain 2; Second of two HU domains found in bacterial proteins ...
 143-178 3.63e-03

CCDC81-like prokaryotic HU domain 2; Second of two HU domains found in bacterial proteins typically fused to a C-terminal transmembrane helix and an extracellular peptidoglycan-binding domain. The HU domains in many of these proteins are predicted to function in tethering the nucleoid to the cell envelope.


The actual alignment was detected with superfamily member pfam18175:

Pssm-ID: 465671  Cd Length: 70  Bit Score: 35.13  E-value: 3.63e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 17533223   143 DGEQISHELFREMLKCDVNELRIHLRTQHTVELSDI 178
Cdd:pfam18175   9 EAEGISYEEALQRIEKEVEELKQELQEGGRVELPNI 44
FBA_2 pfam07735
F-box associated; Most of these proteins contain pfam00646 at the N terminus, suggesting that ...
 152-216 7.48e-03

F-box associated; Most of these proteins contain pfam00646 at the N terminus, suggesting that they are effectors linked with ubiquitination.


:

Pssm-ID: 429626  Cd Length: 67  Bit Score: 34.47  E-value: 7.48e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 17533223   152 FREMLKCDVNELRIHLRTQHtVELSDIdLMVSCKCVALTRITIPSDYLNVLLKKWQA--NRNLTFFS 216
Cdd:pfam07735   2 FQKILIQNLDELTIGDSSVW-ITLDDL-LLINSKKIELDNSRLSLKDLNRFLKHWIKgsNPRLEYLE 66
 
Name Accession Description Interval E-value
FBOX smart00256
A Receptor for Ubiquitination Targets;
14-44 3.10e-04

A Receptor for Ubiquitination Targets;


Pssm-ID: 197608  Cd Length: 41  Bit Score: 37.42  E-value: 3.10e-04
                           10        20        30
                   ....*....|....*....|....*....|.
gi 17533223     14 LPTVVISEVLNHLKNIDICILRTTSRKIRTI 44
Cdd:smart00256   1 LPDEILEEILSKLDPKDLLRLRKVSRKWRSL 31
F-box pfam00646
F-box domain; This domain is approximately 50 amino acids long, and is usually found in the ...
 11-44 5.55e-04

F-box domain; This domain is approximately 50 amino acids long, and is usually found in the N-terminal half of a variety of proteins. Two motifs that are commonly found associated with the F-box domain are the leucine rich repeats (LRRs; pfam00560 and pfam07723) and the WD repeat (pfam00400). The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


Pssm-ID: 425796  Cd Length: 43  Bit Score: 36.75  E-value: 5.55e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 17533223    11 LLNLPTVVISEVLNHLKNIDICILRTTSRKIRTI 44
Cdd:pfam00646   1 LLDLPDDLLLEILSRLDPKDLLRLSLVSKRWRSL 34
HU-CCDC81_bac_2 pfam18175
CCDC81-like prokaryotic HU domain 2; Second of two HU domains found in bacterial proteins ...
 143-178 3.63e-03

CCDC81-like prokaryotic HU domain 2; Second of two HU domains found in bacterial proteins typically fused to a C-terminal transmembrane helix and an extracellular peptidoglycan-binding domain. The HU domains in many of these proteins are predicted to function in tethering the nucleoid to the cell envelope.


Pssm-ID: 465671  Cd Length: 70  Bit Score: 35.13  E-value: 3.63e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 17533223   143 DGEQISHELFREMLKCDVNELRIHLRTQHTVELSDI 178
Cdd:pfam18175   9 EAEGISYEEALQRIEKEVEELKQELQEGGRVELPNI 44
FBA_2 pfam07735
F-box associated; Most of these proteins contain pfam00646 at the N terminus, suggesting that ...
 152-216 7.48e-03

F-box associated; Most of these proteins contain pfam00646 at the N terminus, suggesting that they are effectors linked with ubiquitination.


Pssm-ID: 429626  Cd Length: 67  Bit Score: 34.47  E-value: 7.48e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 17533223   152 FREMLKCDVNELRIHLRTQHtVELSDIdLMVSCKCVALTRITIPSDYLNVLLKKWQA--NRNLTFFS 216
Cdd:pfam07735   2 FQKILIQNLDELTIGDSSVW-ITLDDL-LLINSKKIELDNSRLSLKDLNRFLKHWIKgsNPRLEYLE 66
 
Name Accession Description Interval E-value
FBOX smart00256
A Receptor for Ubiquitination Targets;
14-44 3.10e-04

A Receptor for Ubiquitination Targets;


Pssm-ID: 197608  Cd Length: 41  Bit Score: 37.42  E-value: 3.10e-04
                           10        20        30
                   ....*....|....*....|....*....|.
gi 17533223     14 LPTVVISEVLNHLKNIDICILRTTSRKIRTI 44
Cdd:smart00256   1 LPDEILEEILSKLDPKDLLRLRKVSRKWRSL 31
F-box pfam00646
F-box domain; This domain is approximately 50 amino acids long, and is usually found in the ...
 11-44 5.55e-04

F-box domain; This domain is approximately 50 amino acids long, and is usually found in the N-terminal half of a variety of proteins. Two motifs that are commonly found associated with the F-box domain are the leucine rich repeats (LRRs; pfam00560 and pfam07723) and the WD repeat (pfam00400). The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


Pssm-ID: 425796  Cd Length: 43  Bit Score: 36.75  E-value: 5.55e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 17533223    11 LLNLPTVVISEVLNHLKNIDICILRTTSRKIRTI 44
Cdd:pfam00646   1 LLDLPDDLLLEILSRLDPKDLLRLSLVSKRWRSL 34
HU-CCDC81_bac_2 pfam18175
CCDC81-like prokaryotic HU domain 2; Second of two HU domains found in bacterial proteins ...
 143-178 3.63e-03

CCDC81-like prokaryotic HU domain 2; Second of two HU domains found in bacterial proteins typically fused to a C-terminal transmembrane helix and an extracellular peptidoglycan-binding domain. The HU domains in many of these proteins are predicted to function in tethering the nucleoid to the cell envelope.


Pssm-ID: 465671  Cd Length: 70  Bit Score: 35.13  E-value: 3.63e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 17533223   143 DGEQISHELFREMLKCDVNELRIHLRTQHTVELSDI 178
Cdd:pfam18175   9 EAEGISYEEALQRIEKEVEELKQELQEGGRVELPNI 44
FBA_2 pfam07735
F-box associated; Most of these proteins contain pfam00646 at the N terminus, suggesting that ...
 152-216 7.48e-03

F-box associated; Most of these proteins contain pfam00646 at the N terminus, suggesting that they are effectors linked with ubiquitination.


Pssm-ID: 429626  Cd Length: 67  Bit Score: 34.47  E-value: 7.48e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 17533223   152 FREMLKCDVNELRIHLRTQHtVELSDIdLMVSCKCVALTRITIPSDYLNVLLKKWQA--NRNLTFFS 216
Cdd:pfam07735   2 FQKILIQNLDELTIGDSSVW-ITLDDL-LLINSKKIELDNSRLSLKDLNRFLKHWIKgsNPRLEYLE 66
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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