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Conserved domains on  [gi|392890832|ref|NP_495754|]
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Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 [Caenorhabditis elegans]

Protein Classification

NAD(P)/FAD-dependent oxidoreductase( domain architecture ID 1001407)

NAD(P)/FAD-dependent oxidoreductase catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant; similar to nitrite reductase large subunit NirB

CATH:  3.30.390.30
EC:  1.-.-.-
Gene Ontology:  GO:0016491
PubMed:  2445993
SCOP:  4000121

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
NirB super family cl34210
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
1-472 3.39e-42

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


The actual alignment was detected with superfamily member COG1251:

Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 154.53  E-value: 3.39e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832   1 MKYIIVGGGIAGVSCASQMLqlERSANLEVIIISASSFVksveNYQKIG---QYGEKFDVKETNCH--ELFPDSRIRF-L 74
Cdd:COG1251    2 MRIVIIGAGMAGVRAAEELR--KLDPDGEITVIGAEPHP----PYNRPPlskVLAGETDEEDLLLRpaDFYEENGIDLrL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832  75 NDTVVTWDSSKNEIHLQNNEKLKYDKLCIATGSRPKFQKELGIDRRIVF-LRDTQSAIQLKTKLKNAKNILIVGNGGIAT 153
Cdd:COG1251   76 GTRVTAIDRAARTVTLADGETLPYDKLVLATGSRPRVPPIPGADLPGVFtLRTLDDADALRAALAPGKRVVVIGGGLIGL 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 154 ELIFELKT--FDVTWLIKDPWICASFFPEDIEQFIEKRLlkgridgnkhdgqqkhlqhvaasesvsenmnnpsgpalgpd 231
Cdd:COG1251  156 EAAAALRKrgLEVTVVERAPRLLPRQLDEEAGALLQRLL----------------------------------------- 194

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 232 wcsqidfqkiseksENRSVTILRNCVITS-TDTSQNLSVHYMDKEkmadnQLNPDIFIWAGGVTANSEvWAMNKMLQIte 310
Cdd:COG1251  195 --------------EALGVEVRLGTGVTEiEGDDRVTGVRLADGE-----ELPADLVVVAIGVRPNTE-LARAAGLAV-- 252

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 311 NSGIKVNDACETSLPNVFACGDVCALtttePSTLWQQR--QLWTQARQQGEVCGRAMVAGVEEARMQNMYFELfshctTF 388
Cdd:COG1251  253 DRGIVVDDYLRTSDPDIYAAGDCAEH----PGPVYGRRvlELVAPAYEQARVAAANLAGGPAAYEGSVPSTKL-----KV 323

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 389 FGLKVVFLGDYKPERQVegewkIVLRDADNDQLVRCVVVKNKIVGALLIGETDMEETLENLILNKTDLEGisETFLEPGV 468
Cdd:COG1251  324 FGVDVASAGDAEGDEEV-----VVRGDPARGVYKKLVLRDGRLVGAVLVGDTSDAGALRQLIKNGRPLPP--RALLDAAL 396


                 ....
gi 392890832 469 DLDD 472
Cdd:COG1251  397 PLKE 400
 
Name Accession Description Interval E-value
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
1-472 3.39e-42

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 154.53  E-value: 3.39e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832   1 MKYIIVGGGIAGVSCASQMLqlERSANLEVIIISASSFVksveNYQKIG---QYGEKFDVKETNCH--ELFPDSRIRF-L 74
Cdd:COG1251    2 MRIVIIGAGMAGVRAAEELR--KLDPDGEITVIGAEPHP----PYNRPPlskVLAGETDEEDLLLRpaDFYEENGIDLrL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832  75 NDTVVTWDSSKNEIHLQNNEKLKYDKLCIATGSRPKFQKELGIDRRIVF-LRDTQSAIQLKTKLKNAKNILIVGNGGIAT 153
Cdd:COG1251   76 GTRVTAIDRAARTVTLADGETLPYDKLVLATGSRPRVPPIPGADLPGVFtLRTLDDADALRAALAPGKRVVVIGGGLIGL 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 154 ELIFELKT--FDVTWLIKDPWICASFFPEDIEQFIEKRLlkgridgnkhdgqqkhlqhvaasesvsenmnnpsgpalgpd 231
Cdd:COG1251  156 EAAAALRKrgLEVTVVERAPRLLPRQLDEEAGALLQRLL----------------------------------------- 194

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 232 wcsqidfqkiseksENRSVTILRNCVITS-TDTSQNLSVHYMDKEkmadnQLNPDIFIWAGGVTANSEvWAMNKMLQIte 310
Cdd:COG1251  195 --------------EALGVEVRLGTGVTEiEGDDRVTGVRLADGE-----ELPADLVVVAIGVRPNTE-LARAAGLAV-- 252

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 311 NSGIKVNDACETSLPNVFACGDVCALtttePSTLWQQR--QLWTQARQQGEVCGRAMVAGVEEARMQNMYFELfshctTF 388
Cdd:COG1251  253 DRGIVVDDYLRTSDPDIYAAGDCAEH----PGPVYGRRvlELVAPAYEQARVAAANLAGGPAAYEGSVPSTKL-----KV 323

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 389 FGLKVVFLGDYKPERQVegewkIVLRDADNDQLVRCVVVKNKIVGALLIGETDMEETLENLILNKTDLEGisETFLEPGV 468
Cdd:COG1251  324 FGVDVASAGDAEGDEEV-----VVRGDPARGVYKKLVLRDGRLVGAVLVGDTSDAGALRQLIKNGRPLPP--RALLDAAL 396


                 ....
gi 392890832 469 DLDD 472
Cdd:COG1251  397 PLKE 400
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 1-358 2.41e-23

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 99.70  E-value: 2.41e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832    1 MKYIIVGGGIAGVSCAsqmLQLeRSANLEVIIISA------------SSFVKSVENYQKIGQYGEKFDVKETNCHELFPD 68
Cdd:pfam07992   1 YDVVVIGGGPAGLAAA---LTL-AQLGGKVTLIEDegtcpyggcvlsKALLGAAEAPEIASLWADLYKRKEEVVKKLNNG 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832   69 sRIRFLNDTVVTWDSSKNEIHLQNN-----EKLKYDKLCIATGSRPKF----QKELGIDRRIVFLRDTQsAIQLKTKlkn 139
Cdd:pfam07992  77 -IEVLLGTEVVSIDPGAKKVVLEELvdgdgETITYDRLVIATGARPRLppipGVELNVGFLVRTLDSAE-ALRLKLL--- 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832  140 AKNILIVGNGGIATELIFELKTF--DVTWLIKDPWIcASFFPEDIEQFIEKRLlkgridgnkhdgqqkhlqhvaasesvs 217
Cdd:pfam07992 152 PKRVVVVGGGYIGVELAAALAKLgkEVTLIEALDRL-LRAFDEEISAALEKAL--------------------------- 203

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832  218 enmnnpsgpalgpdwcsqidfqkiseksENRSVTILRNCVITS-TDTSQNLSVHYMDKEKmadnqLNPDIFIWAGGVTAN 296
Cdd:pfam07992 204 ----------------------------EKNGVEVRLGTSVKEiIGDGDGVEVILKDGTE-----IDADLVVVAIGRRPN 250

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 392890832  297 SEvWAMNKMLQITENSGIKVNDACETSLPNVFACGDVcaltttepstLWQQRQLWTQARQQG 358
Cdd:pfam07992 251 TE-LLEAAGLELDERGGIVVDEYLRTSVPGIYAAGDC----------RVGGPELAQNAVAQG 301
PRK09754 PRK09754
phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional
 3-452 1.20e-15

phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional


Pssm-ID: 170080 [Multi-domain]  Cd Length: 396  Bit Score: 78.43  E-value: 1.20e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832   3 YIIVGGGIAGVSCASQMLQLERSAnlEVIIISASSFVKsvenYQKIGQYGEKFDVKETNCHELFP-----DSRIRF-LND 76
Cdd:PRK09754   6 IIIVGGGQAAAMAAASLRQQGFTG--ELHLFSDERHLP----YERPPLSKSMLLEDSPQLQQVLPanwwqENNVHLhSGV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832  77 TVVTWDSSKNEIHLQNNEKLKYDKLCIATGSRPK---FQKELGidRRIVFLRDTQSAIQLKTKLKNAKNILIVGNGGIAT 153
Cdd:PRK09754  80 TIKTLGRDTRELVLTNGESWHWDQLFIATGAAARplpLLDALG--ERCFTLRHAGDAARLREVLQPERSVVIVGAGTIGL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 154 ELifelktfdvtwlikdpwicASFFPEdieqfiekrllkgridgnkhdgqqkhlqhVAASESVSENMNNPSG---PALGP 230
Cdd:PRK09754 158 EL-------------------AASATQ-----------------------------RRCKVTVIELAATVMGrnaPPPVQ 189

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 231 DWCSQidfqkiseKSENRSVTILRNCVITSTDTSQNLSVHYMDKEKmadnqLNPDIFIWAGGVTANSEVwAMNKMLQITe 310
Cdd:PRK09754 190 RYLLQ--------RHQQAGVRILLNNAIEHVVDGEKVELTLQSGET-----LQADVVIYGIGISANDQL-AREANLDTA- 254

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 311 nSGIKVNDACETSLPNVFACGDVCalTTTEPSTLWQQRQLWTQARQQGEVCGRAMVaGVEEARMQNMYFelfshCTTFFG 390
Cdd:PRK09754 255 -NGIVIDEACRTCDPAIFAGGDVA--ITRLDNGALHRCESWENANNQAQIAAAAML-GLPLPLLPPPWF-----WSDQYS 325

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 392890832 391 LKVVFLGDYKPErqvegEWKIvLRDADNDQLVRCVVVKNKIVGALLIGETDMEETLENLILN 452
Cdd:PRK09754 326 DNLQFIGDMRGD-----DWLC-RGNPETQKAIWFNLQNGVLIGAVTLNQGREIRPIRKWIQS 381
nitri_red_nirB TIGR02374
nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen ...
 4-460 6.87e-14

nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen metabolism]


Pssm-ID: 162827 [Multi-domain]  Cd Length: 785  Bit Score: 74.09  E-value: 6.87e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832    4 IIVGGGIAGVSCASQMLQLERsANLEVIIISASSFVksveNYQKIG-----QYGEKFDVKETNCHELFPDSRIR-FLNDT 77
Cdd:TIGR02374   2 VLVGNGMAGHRCIEEVLKLNR-HMFEITIFGEEPHP----NYNRILlssvlQGEADLDDITLNSKDWYEKHGITlYTGET 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832   78 VVTWDSSKNEIHLQNNEKLKYDKLCIATGSRPKFQKELGIDRRIVF-LRDTQSAIQLKTKLKNAKNILIVGNGGIATELI 156
Cdd:TIGR02374  77 VIQIDTDQKQVITDAGRTLSYDKLILATGSYPFILPIPGADKKGVYvFRTIEDLDAIMAMAQRFKKAAVIGGGLLGLEAA 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832  157 FELKTFdvtwlikdpwicasffpedieqfiekrllkgridgnkhdGQQKHLQHVAasesvsenmnnpsgPALGPDWCSQI 236
Cdd:TIGR02374 157 VGLQNL---------------------------------------GMDVSVIHHA--------------PGLMAKQLDQT 183

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832  237 DFQKISEKSENRSVTILrncviTSTDTSQNLSVHYMDKEKMAD-NQLNPDIFIWAGGVTANSEVwAMNKMLQIteNSGIK 315
Cdd:TIGR02374 184 AGRLLQRELEQKGLTFL-----LEKDTVEIVGATKADRIRFKDgSSLEADLIVMAAGIRPNDEL-AVSAGIKV--NRGII 255

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832  316 VNDACETSLPNVFACGDVCAltttepstlWQQR--QLWTQARQQGEVCGRAMVaGVEEARMQNmyfELFSHCTTFFGLKV 393
Cdd:TIGR02374 256 VNDSMQTSDPDIYAVGECAE---------HNGRvyGLVAPLYEQAKVLADHIC-GVECEEYEG---SDLSAKLKLLGVDV 322

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 392890832  394 VFLGDYKperQVEGEWKIVLRDADNDQLVRCVVVKNKIVGALLIGETDMEETLENLILNKTDLEGIS 460
Cdd:TIGR02374 323 WSAGDAQ---ETERTTSIKIYDEQKGIYKKLVLSDDKLLGAVLFGDTSDYGRLLDMVLKQADISEDP 386
 
Name Accession Description Interval E-value
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
1-472 3.39e-42

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 154.53  E-value: 3.39e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832   1 MKYIIVGGGIAGVSCASQMLqlERSANLEVIIISASSFVksveNYQKIG---QYGEKFDVKETNCH--ELFPDSRIRF-L 74
Cdd:COG1251    2 MRIVIIGAGMAGVRAAEELR--KLDPDGEITVIGAEPHP----PYNRPPlskVLAGETDEEDLLLRpaDFYEENGIDLrL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832  75 NDTVVTWDSSKNEIHLQNNEKLKYDKLCIATGSRPKFQKELGIDRRIVF-LRDTQSAIQLKTKLKNAKNILIVGNGGIAT 153
Cdd:COG1251   76 GTRVTAIDRAARTVTLADGETLPYDKLVLATGSRPRVPPIPGADLPGVFtLRTLDDADALRAALAPGKRVVVIGGGLIGL 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 154 ELIFELKT--FDVTWLIKDPWICASFFPEDIEQFIEKRLlkgridgnkhdgqqkhlqhvaasesvsenmnnpsgpalgpd 231
Cdd:COG1251  156 EAAAALRKrgLEVTVVERAPRLLPRQLDEEAGALLQRLL----------------------------------------- 194

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 232 wcsqidfqkiseksENRSVTILRNCVITS-TDTSQNLSVHYMDKEkmadnQLNPDIFIWAGGVTANSEvWAMNKMLQIte 310
Cdd:COG1251  195 --------------EALGVEVRLGTGVTEiEGDDRVTGVRLADGE-----ELPADLVVVAIGVRPNTE-LARAAGLAV-- 252

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 311 NSGIKVNDACETSLPNVFACGDVCALtttePSTLWQQR--QLWTQARQQGEVCGRAMVAGVEEARMQNMYFELfshctTF 388
Cdd:COG1251  253 DRGIVVDDYLRTSDPDIYAAGDCAEH----PGPVYGRRvlELVAPAYEQARVAAANLAGGPAAYEGSVPSTKL-----KV 323

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 389 FGLKVVFLGDYKPERQVegewkIVLRDADNDQLVRCVVVKNKIVGALLIGETDMEETLENLILNKTDLEGisETFLEPGV 468
Cdd:COG1251  324 FGVDVASAGDAEGDEEV-----VVRGDPARGVYKKLVLRDGRLVGAVLVGDTSDAGALRQLIKNGRPLPP--RALLDAAL 396


                 ....
gi 392890832 469 DLDD 472
Cdd:COG1251  397 PLKE 400
FadH2 COG0446
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase ...
 23-400 2.30e-26

NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism];


Pssm-ID: 440215 [Multi-domain]  Cd Length: 322  Bit Score: 108.75  E-value: 2.30e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832  23 ERSANLEVIIISASSFVksveNYQKIGQY----GEKFDVKETNCH--ELFPDSRIRF-LNDTVVTWDSSKNEIHLQNNEK 95
Cdd:COG0446    1 RLGPDAEITVIEKGPHH----SYQPCGLPyyvgGGIKDPEDLLVRtpESFERKGIDVrTGTEVTAIDPEAKTVTLRDGET 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832  96 LKYDKLCIATGSRPKFQKELGIDRRIVF-LRDTQSAIQLKTKLKN--AKNILIVGNGGIATELIFELKT--FDVTWLIKD 170
Cdd:COG0446   77 LSYDKLVLATGARPRPPPIPGLDLPGVFtLRTLDDADALREALKEfkGKRAVVIGGGPIGLELAEALRKrgLKVTLVERA 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 171 PWICASfFPEDIEQFIEKRLlkgridgnkhdgqqkhlqhvaasesvsenmnnpsgpalgpdwcsqidfqkiseksENRSV 250
Cdd:COG0446  157 PRLLGV-LDPEMAALLEEEL-------------------------------------------------------REHGV 180

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 251 TILRNCVITSTDTSQNLSVHYMDKEKmadnqLNPDIFIWAGGVTANSEvWAMNKMLQITENSGIKVNDACETSLPNVFAC 330
Cdd:COG0446  181 ELRLGETVVAIDGDDKVAVTLTDGEE-----IPADLVVVAPGVRPNTE-LAKDAGLALGERGWIKVDETLQTSDPDVYAA 254

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 331 GDvCALTTTEPSTLWQQRQLWTQARQQGEVCGRAMvAGVEEArmqnmYFELFSHCTTFFGLKVVFLGDYK 400
Cdd:COG0446  255 GD-CAEVPHPVTGKTVYIPLASAANKQGRVAAENI-LGGPAP-----FPGLGTFISKVFDLCIASTGTGR 317
Ndh COG1252
NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];
4-368 2.39e-25

NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];


Pssm-ID: 440864 [Multi-domain]  Cd Length: 386  Bit Score: 107.14  E-value: 2.39e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832   4 IIVGGGIAGVSCAsQMLQLERSANLEVIIISASS-FVKSVENYQKI-GQYGE---KFDVKEtncheLFPDSRIRFLNDTV 78
Cdd:COG1252    5 VIVGGGFAGLEAA-RRLRKKLGGDAEVTLIDPNPyHLFQPLLPEVAaGTLSPddiAIPLRE-----LLRRAGVRFIQGEV 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832  79 VTWDSSKNEIHLQNNEKLKYDKLCIATGSRPKFQKELGIDRRIVFLRDTQSAIQLKTKLKNA---------KNILIVGNG 149
Cdd:COG1252   79 TGIDPEARTVTLADGRTLSYDYLVIATGSVTNFFGIPGLAEHALPLKTLEDALALRERLLAAferaerrrlLTIVVVGGG 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 150 GIATELIFELktfdvtwlikdpwicasffpediEQFIEKRLLKGRIDGNKhdgQQKHLqhVAASESVsenmnnpsGPALG 229
Cdd:COG1252  159 PTGVELAGEL-----------------------AELLRKLLRYPGIDPDK---VRITL--VEAGPRI--------LPGLG 202

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 230 PdwcsqiDFQKISEKS-ENRSVTILRNCVITSTDTSqnlSVHYMDKEKmadnqLNPDIFIWAGGVTANSevWAMNKMLQI 308
Cdd:COG1252  203 E------KLSEAAEKElEKRGVEVHTGTRVTEVDAD---GVTLEDGEE-----IPADTVIWAAGVKAPP--LLADLGLPT 266

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 392890832 309 TENSGIKVNDACET-SLPNVFACGDVCALTTTEPSTLWQQRQLwtqARQQGEVCGR---AMVAG 368
Cdd:COG1252  267 DRRGRVLVDPTLQVpGHPNVFAIGDCAAVPDPDGKPVPKTAQA---AVQQAKVLAKniaALLRG 327
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 1-358 2.41e-23

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 99.70  E-value: 2.41e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832    1 MKYIIVGGGIAGVSCAsqmLQLeRSANLEVIIISA------------SSFVKSVENYQKIGQYGEKFDVKETNCHELFPD 68
Cdd:pfam07992   1 YDVVVIGGGPAGLAAA---LTL-AQLGGKVTLIEDegtcpyggcvlsKALLGAAEAPEIASLWADLYKRKEEVVKKLNNG 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832   69 sRIRFLNDTVVTWDSSKNEIHLQNN-----EKLKYDKLCIATGSRPKF----QKELGIDRRIVFLRDTQsAIQLKTKlkn 139
Cdd:pfam07992  77 -IEVLLGTEVVSIDPGAKKVVLEELvdgdgETITYDRLVIATGARPRLppipGVELNVGFLVRTLDSAE-ALRLKLL--- 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832  140 AKNILIVGNGGIATELIFELKTF--DVTWLIKDPWIcASFFPEDIEQFIEKRLlkgridgnkhdgqqkhlqhvaasesvs 217
Cdd:pfam07992 152 PKRVVVVGGGYIGVELAAALAKLgkEVTLIEALDRL-LRAFDEEISAALEKAL--------------------------- 203

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832  218 enmnnpsgpalgpdwcsqidfqkiseksENRSVTILRNCVITS-TDTSQNLSVHYMDKEKmadnqLNPDIFIWAGGVTAN 296
Cdd:pfam07992 204 ----------------------------EKNGVEVRLGTSVKEiIGDGDGVEVILKDGTE-----IDADLVVVAIGRRPN 250

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 392890832  297 SEvWAMNKMLQITENSGIKVNDACETSLPNVFACGDVcaltttepstLWQQRQLWTQARQQG 358
Cdd:pfam07992 251 TE-LLEAAGLELDERGGIVVDEYLRTSVPGIYAAGDC----------RVGGPELAQNAVAQG 301
PRK09754 PRK09754
phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional
 3-452 1.20e-15

phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional


Pssm-ID: 170080 [Multi-domain]  Cd Length: 396  Bit Score: 78.43  E-value: 1.20e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832   3 YIIVGGGIAGVSCASQMLQLERSAnlEVIIISASSFVKsvenYQKIGQYGEKFDVKETNCHELFP-----DSRIRF-LND 76
Cdd:PRK09754   6 IIIVGGGQAAAMAAASLRQQGFTG--ELHLFSDERHLP----YERPPLSKSMLLEDSPQLQQVLPanwwqENNVHLhSGV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832  77 TVVTWDSSKNEIHLQNNEKLKYDKLCIATGSRPK---FQKELGidRRIVFLRDTQSAIQLKTKLKNAKNILIVGNGGIAT 153
Cdd:PRK09754  80 TIKTLGRDTRELVLTNGESWHWDQLFIATGAAARplpLLDALG--ERCFTLRHAGDAARLREVLQPERSVVIVGAGTIGL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 154 ELifelktfdvtwlikdpwicASFFPEdieqfiekrllkgridgnkhdgqqkhlqhVAASESVSENMNNPSG---PALGP 230
Cdd:PRK09754 158 EL-------------------AASATQ-----------------------------RRCKVTVIELAATVMGrnaPPPVQ 189

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 231 DWCSQidfqkiseKSENRSVTILRNCVITSTDTSQNLSVHYMDKEKmadnqLNPDIFIWAGGVTANSEVwAMNKMLQITe 310
Cdd:PRK09754 190 RYLLQ--------RHQQAGVRILLNNAIEHVVDGEKVELTLQSGET-----LQADVVIYGIGISANDQL-AREANLDTA- 254

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 311 nSGIKVNDACETSLPNVFACGDVCalTTTEPSTLWQQRQLWTQARQQGEVCGRAMVaGVEEARMQNMYFelfshCTTFFG 390
Cdd:PRK09754 255 -NGIVIDEACRTCDPAIFAGGDVA--ITRLDNGALHRCESWENANNQAQIAAAAML-GLPLPLLPPPWF-----WSDQYS 325

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 392890832 391 LKVVFLGDYKPErqvegEWKIvLRDADNDQLVRCVVVKNKIVGALLIGETDMEETLENLILN 452
Cdd:PRK09754 326 DNLQFIGDMRGD-----DWLC-RGNPETQKAIWFNLQNGVLIGAVTLNQGREIRPIRKWIQS 381
PRK09564 PRK09564
coenzyme A disulfide reductase; Reviewed
 1-335 3.09e-15

coenzyme A disulfide reductase; Reviewed


Pssm-ID: 181958 [Multi-domain]  Cd Length: 444  Bit Score: 77.39  E-value: 3.09e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832   1 MKYIIVGGGIAGVSCASQMLQLERSanLEVIIISASSFVksveNYQKIG-QY--GEKFDVKET---NCHELFPDSRIR-F 73
Cdd:PRK09564   1 MKIIIIGGTAAGMSAAAKAKRLNKE--LEITVYEKTDIV----SFGACGlPYfvGGFFDDPNTmiaRTPEEFIKSGIDvK 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832  74 LNDTVVTWDSSKNEI---HLQNNEKL--KYDKLCIATGSRPKFQKELGIDRRIVF-LRDTQSAIQLKTKLK--NAKNILI 145
Cdd:PRK09564  75 TEHEVVKVDAKNKTItvkNLKTGSIFndTYDKLMIATGARPIIPPIKNINLENVYtLKSMEDGLALKELLKdeEIKNIVI 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 146 VGNGGIATELIFELKTF--DVTWLIKDPWICASFFPEDIEQFIEKRLLKGRIDgnkhdgqqKHLqhvaaSESVSEnmnnp 223
Cdd:PRK09564 155 IGAGFIGLEAVEAAKHLgkNVRIIQLEDRILPDSFDKEITDVMEEELRENGVE--------LHL-----NEFVKS----- 216

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 224 sgpalgpdwcsqIDFQKiseksenrSVTIlrncVITstdtsqnlsvhymDKekmadNQLNPDIFIWAGGVTANSEvWAMN 303
Cdd:PRK09564 217 ------------LIGED--------KVEG----VVT-------------DK-----GEYEADVVIVATGVKPNTE-FLED 253

                        330       340       350
                 ....*....|....*....|....*....|..
gi 392890832 304 KMLQITENSGIKVNDACETSLPNVFACGDvCA 335
Cdd:PRK09564 254 TGLKTLKNGAIIVDEYGETSIENIYAAGD-CA 284
nitri_red_nirB TIGR02374
nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen ...
 4-460 6.87e-14

nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen metabolism]


Pssm-ID: 162827 [Multi-domain]  Cd Length: 785  Bit Score: 74.09  E-value: 6.87e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832    4 IIVGGGIAGVSCASQMLQLERsANLEVIIISASSFVksveNYQKIG-----QYGEKFDVKETNCHELFPDSRIR-FLNDT 77
Cdd:TIGR02374   2 VLVGNGMAGHRCIEEVLKLNR-HMFEITIFGEEPHP----NYNRILlssvlQGEADLDDITLNSKDWYEKHGITlYTGET 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832   78 VVTWDSSKNEIHLQNNEKLKYDKLCIATGSRPKFQKELGIDRRIVF-LRDTQSAIQLKTKLKNAKNILIVGNGGIATELI 156
Cdd:TIGR02374  77 VIQIDTDQKQVITDAGRTLSYDKLILATGSYPFILPIPGADKKGVYvFRTIEDLDAIMAMAQRFKKAAVIGGGLLGLEAA 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832  157 FELKTFdvtwlikdpwicasffpedieqfiekrllkgridgnkhdGQQKHLQHVAasesvsenmnnpsgPALGPDWCSQI 236
Cdd:TIGR02374 157 VGLQNL---------------------------------------GMDVSVIHHA--------------PGLMAKQLDQT 183

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832  237 DFQKISEKSENRSVTILrncviTSTDTSQNLSVHYMDKEKMAD-NQLNPDIFIWAGGVTANSEVwAMNKMLQIteNSGIK 315
Cdd:TIGR02374 184 AGRLLQRELEQKGLTFL-----LEKDTVEIVGATKADRIRFKDgSSLEADLIVMAAGIRPNDEL-AVSAGIKV--NRGII 255

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832  316 VNDACETSLPNVFACGDVCAltttepstlWQQR--QLWTQARQQGEVCGRAMVaGVEEARMQNmyfELFSHCTTFFGLKV 393
Cdd:TIGR02374 256 VNDSMQTSDPDIYAVGECAE---------HNGRvyGLVAPLYEQAKVLADHIC-GVECEEYEG---SDLSAKLKLLGVDV 322

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 392890832  394 VFLGDYKperQVEGEWKIVLRDADNDQLVRCVVVKNKIVGALLIGETDMEETLENLILNKTDLEGIS 460
Cdd:TIGR02374 323 WSAGDAQ---ETERTTSIKIYDEQKGIYKKLVLSDDKLLGAVLFGDTSDYGRLLDMVLKQADISEDP 386
Lpd COG1249
Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex ...
 1-333 1.06e-11

Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase [Energy production and conversion]; Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase is part of the Pathway/BioSystem: Glycine cleavagePyruvate oxidation


Pssm-ID: 440861 [Multi-domain]  Cd Length: 456  Bit Score: 66.65  E-value: 1.06e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832   1 MKY--IIVGGGIAGVSCASQMLQLersaNLEVIIISAS---------------SFVKSVENYQKI---GQYG-----EKF 55
Cdd:COG1249    2 KDYdlVVIGAGPGGYVAAIRAAQL----GLKVALVEKGrlggtclnvgcipskALLHAAEVAHEArhaAEFGisagaPSV 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832  56 DVKETNCH-------------ELFPDSRIRFLNDT--VVtwdsSKNEIHLQNNEKLKYDKLCIATGSRPKFQKELGID-R 119
Cdd:COG1249   78 DWAALMARkdkvvdrlrggveELLKKNGVDVIRGRarFV----DPHTVEVTGGETLTADHIVIATGSRPRVPPIPGLDeV 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 120 RIVflrDTQSAIQLKTKlknAKNILIVGNGGIATEL--IFelKTF--DVTWLIKDPWIcASFFPEDIEQFIEKRLlkgri 195
Cdd:COG1249  154 RVL---TSDEALELEEL---PKSLVVIGGGYIGLEFaqIF--ARLgsEVTLVERGDRL-LPGEDPEISEALEKAL----- 219

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 196 dgnkhdgqqkhlqhvaasesvsenmnnpsgpalgpdwcsqidfqkiseksENRSVTILRNCVITS-TDTSQNLSVHYMDK 274
Cdd:COG1249  220 --------------------------------------------------EKEGIDILTGAKVTSvEKTGDGVTVTLEDG 249

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 275 EKMAdnQLNPDIFIWAGGVTANSEVWAMNKM-LQITENSGIKVNDACETSLPNVFACGDV 333
Cdd:COG1249  250 GGEE--AVEADKVLVATGRRPNTDGLGLEAAgVELDERGGIKVDEYLRTSVPGIYAIGDV 307
PRK13512 PRK13512
coenzyme A disulfide reductase; Provisional
 1-333 8.05e-10

coenzyme A disulfide reductase; Provisional


Pssm-ID: 184103 [Multi-domain]  Cd Length: 438  Bit Score: 60.57  E-value: 8.05e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832   1 MKYIIVGGGIAGVSCASQMLQLERSAnlEVIIISAS---SFV---------KSVENYQKI-----GQYGEKFDVKETNCH 63
Cdd:PRK13512   2 PKIIVVGAVAGGATCASQIRRLDKES--DIIIFEKDrdmSFAncalpyyigEVVEDRKYAlaytpEKFYDRKQITVKTYH 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832  64 ELfpdSRIRFLNDTVVTWDSSKNEIHLQNneklkYDKLCIATGSRpkfQKELGIDRRIVF----LRDTQsAIQLKTKLKN 139
Cdd:PRK13512  80 EV---IAINDERQTVTVLNRKTNEQFEES-----YDKLILSPGAS---ANSLGFESDITFtlrnLEDTD-AIDQFIKANQ 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 140 AKNILIVGNGGIATELIFELKT--FDVTWLIKDPWIcasffpedieqfiekrllkgridgNKHdgqqkhlqhvaasesVS 217
Cdd:PRK13512 148 VDKALVVGAGYISLEVLENLYErgLHPTLIHRSDKI------------------------NKL---------------MD 188

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 218 ENMNNPsgpalgpdwcsqidfqkISEKSENRSVTILRNCVITSTDTSqnlSVHYmdkekMADNQLNPDIFIWAGGVTANS 297
Cdd:PRK13512 189 ADMNQP-----------------ILDELDKREIPYRLNEEIDAINGN---EVTF-----KSGKVEHYDMIIEGVGTHPNS 243

                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 392890832 298 EvWAMNKMLQITENSGIKVNDACETSLPNVFACGDV 333
Cdd:PRK13512 244 K-FIESSNIKLDDKGFIPVNDKFETNVPNIYAIGDI 278
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
4-334 9.61e-09

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 56.67  E-value: 9.61e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832   4 IIVGGGIAGVSCAsqmLQLeRSANLEVIIISASSF------VKSVENY---------QKIGQYG----EKFDVketnche 64
Cdd:COG0492    4 VIIGAGPAGLTAA---IYA-ARAGLKTLVIEGGEPggqlatTKEIENYpgfpegisgPELAERLreqaERFGA------- 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832  65 lfpdsriRFLNDTVVTWDSSKN--EIHLQNNEKLKYDKLCIATGSRPKfqkELGI-----------------DRRivFLR 125
Cdd:COG0492   73 -------EILLEEVTSVDKDDGpfRVTTDDGTEYEAKAVIIATGAGPR---KLGLpgeeefegrgvsycatcDGF--FFR 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 126 DtqsaiqlktklknaKNILIVGNGGIATELIFELKTF--DVTWLIKdpwicasffpedieqfiekrllkgridGNKHDGQ 203
Cdd:COG0492  141 G--------------KDVVVVGGGDSALEEALYLTKFasKVTLIHR---------------------------RDELRAS 179

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 204 QKHLQHVAASESVSENmnnpsgpalgpdWCSQIDfqKISEKSENRSVTIlRNcviTSTDTSQNLSVHYmdkekmadnqln 283
Cdd:COG0492  180 KILVERLRANPKIEVL------------WNTEVT--EIEGDGRVEGVTL-KN---VKTGEEKELEVDG------------ 229

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|.
gi 392890832 284 pdIFIwAGGVTANSEvWAMNKMLQITENSGIKVNDACETSLPNVFACGDVC 334
Cdd:COG0492  230 --VFV-AIGLKPNTE-LLKGLGLELDEDGYIVVDEDMETSVPGVFAAGDVR 276
PRK04965 PRK04965
NADH:flavorubredoxin reductase NorW;
70-335 1.62e-07

NADH:flavorubredoxin reductase NorW;


Pssm-ID: 179902 [Multi-domain]  Cd Length: 377  Bit Score: 53.38  E-value: 1.62e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832  70 RIRFLNDTVVTWDSSKNEIHLQNNEKLKYDKLCIATGSRPkFQKELGIDRRIVFLRDTQSAIQLKTKLKNAKNILIVGNG 149
Cdd:PRK04965  72 NLRLFPHTWVTDIDAEAQVVKSQGNQWQYDKLVLATGASA-FVPPIPGRELMLTLNSQQEYRAAETQLRDAQRVLVVGGG 150

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 150 GIATELIFELKTFDVTWLIKDP--WICASFFPEDIEQFIEKRLLKgridgnkhdgQQKHLQhvaasesvsenmnnpsgpa 227
Cdd:PRK04965 151 LIGTELAMDLCRAGKAVTLVDNaaSLLASLMPPEVSSRLQHRLTE----------MGVHLL------------------- 201

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 228 lgpdwcsqidfqkiseksenrsvtiLRNCVITSTDTSQNLSVHYMDkekmaDNQLNPDIFIWAGGVTANSEVwAMNKMLQ 307
Cdd:PRK04965 202 -------------------------LKSQLQGLEKTDSGIRATLDS-----GRSIEVDAVIAAAGLRPNTAL-ARRAGLA 250

                        250       260
                 ....*....|....*....|....*...
gi 392890832 308 IteNSGIKVNDACETSLPNVFACGDvCA 335
Cdd:PRK04965 251 V--NRGIVVDSYLQTSAPDIYALGD-CA 275
PRK07251 PRK07251
FAD-containing oxidoreductase;
285-333 5.02e-06

FAD-containing oxidoreductase;


Pssm-ID: 180907 [Multi-domain]  Cd Length: 438  Bit Score: 48.59  E-value: 5.02e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 392890832 285 DIFIWAGGVTANSEVWAM-NKMLQITENSGIKVNDACETSLPNVFACGDV 333
Cdd:PRK07251 243 DALLYATGRKPNTEPLGLeNTDIELTERGAIKVDDYCQTSVPGVFAVGDV 292
PRK06116 PRK06116
glutathione reductase; Validated
 92-333 9.94e-05

glutathione reductase; Validated


Pssm-ID: 235701 [Multi-domain]  Cd Length: 450  Bit Score: 44.76  E-value: 9.94e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832  92 NNEKLKYDKLCIATGSRPKFQ----KELGIDRRIVFLRDTQSaiqlktklknaKNILIVGNGGIATEL--IF-ELKTfDV 164
Cdd:PRK06116 126 NGERYTADHILIATGGRPSIPdipgAEYGITSDGFFALEELP-----------KRVAVVGAGYIAVEFagVLnGLGS-ET 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 165 TWLIKDPWICASFFPeDIEQFIekrllkgridgnkHDGQQKHlqhvaasesvsenmnnpsgpalGPDWCSQIDFQKIsEK 244
Cdd:PRK06116 194 HLFVRGDAPLRGFDP-DIRETL-------------VEEMEKK----------------------GIRLHTNAVPKAV-EK 236

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 245 SENRSvtilrncvitstdtsqnLSVHYMDKEkmadnQLNPDIFIWAGGVTANSEVWAMNKM-LQITENSGIKVNDACETS 323
Cdd:PRK06116 237 NADGS-----------------LTLTLEDGE-----TLTVDCLIWAIGREPNTDGLGLENAgVKLNEKGYIIVDEYQNTN 294

                        250
                 ....*....|
gi 392890832 324 LPNVFACGDV 333
Cdd:PRK06116 295 VPGIYAVGDV 304
PTZ00318 PTZ00318
NADH dehydrogenase-like protein; Provisional
 71-185 2.14e-04

NADH dehydrogenase-like protein; Provisional


Pssm-ID: 185553 [Multi-domain]  Cd Length: 424  Bit Score: 43.60  E-value: 2.14e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832  71 IRFLNDTVVTWDSSKNEIHLQNNEKLKYDKLCIATGSRPKFQKELGIDRRIVFLRDTQSAIQLKTKLknAKNILIVGNGG 150
Cdd:PTZ00318  87 VDFEEKRVKCGVVSKSNNANVNTFSVPYDKLVVAHGARPNTFNIPGVEERAFFLKEVNHARGIRKRI--VQCIERASLPT 164

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 392890832 151 IATELIFELKTFDVTWL----IKDPWICASFFPEDIEQF 185
Cdd:PTZ00318 165 TSVEERKRLLHFVVVGGgptgVEFAAELADFFRDDVRNL 203
PRK06327 PRK06327
dihydrolipoamide dehydrogenase; Validated
 258-333 3.49e-04

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235779 [Multi-domain]  Cd Length: 475  Bit Score: 42.99  E-value: 3.49e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 392890832 258 ITSTDTSQN-LSVHYMDKEKMAdNQLNPDIFIWAGGVTANSE-VWAMNKMLQITENSGIKVNDACETSLPNVFACGDV 333
Cdd:PRK06327 247 IGEIKTGGKgVSVAYTDADGEA-QTLEVDKLIVSIGRVPNTDgLGLEAVGLKLDERGFIPVDDHCRTNVPNVYAIGDV 323
Rubredoxin_C pfam18267
Rubredoxin NAD+ reductase C-terminal domain; This is the C-terminal domain of NADH rubredoxin ...
 388-454 3.54e-04

Rubredoxin NAD+ reductase C-terminal domain; This is the C-terminal domain of NADH rubredoxin oxidoreductase present in Clostridium acetobutylicum. The majority of obligatory anaerobes detoxify micro-aerobic environments by consuming O2 via H2O-forming NADH oxidase. This enzyme offers an alternate reaction pathway for scavenging of O2 and reactive oxygen species, wherein the reducing equivalent is obtained from NADH.


Pssm-ID: 408082 [Multi-domain]  Cd Length: 70  Bit Score: 38.69  E-value: 3.54e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 392890832  388 FFGLKVVFLGDYKPERQVEgewKIVLRDADNDQLVRCVVVKNKIVGALLIGETDMEETLENLILNKT 454
Cdd:pfam18267   7 VFGIDLFSMGDIEENDNAE---EIVKVDASNGIYKKLFIRDGKLVGAILIGDTSESPKLKKAIEKKI 70
PRK06416 PRK06416
dihydrolipoamide dehydrogenase; Reviewed
 103-333 3.92e-04

dihydrolipoamide dehydrogenase; Reviewed


Pssm-ID: 235798 [Multi-domain]  Cd Length: 462  Bit Score: 42.83  E-value: 3.92e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 103 IATGSRPKFQKELGIDRRIVFlrDTQSAIQLKTKlknAKNILIVGNGGIATELIFELKTF--DVTWLIKDPWICASfFPE 180
Cdd:PRK06416 140 LATGSRPRELPGIEIDGRVIW--TSDEALNLDEV---PKSLVVIGGGYIGVEFASAYASLgaEVTIVEALPRILPG-EDK 213

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 181 DIEQFIEKRLLKGRIdgnkhdgqqkhlqhvaasESVSENMnnpsgpalgpdwcsqidFQKISEksenrsvtilrncvits 260
Cdd:PRK06416 214 EISKLAERALKKRGI------------------KIKTGAK-----------------AKKVEQ----------------- 241

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 392890832 261 tdTSQNLSVHYMDKEKmaDNQLNPDIFIWAGGVTANSEVWAMNKmLQITENSG-IKVNDACETSLPNVFACGDV 333
Cdd:PRK06416 242 --TDDGVTVTLEDGGK--EETLEADYVLVAVGRRPNTENLGLEE-LGVKTDRGfIEVDEQLRTNVPNIYAIGDI 310
sdhA PRK06263
succinate dehydrogenase flavoprotein subunit; Reviewed
 313-334 2.33e-03

succinate dehydrogenase flavoprotein subunit; Reviewed


Pssm-ID: 235758 [Multi-domain]  Cd Length: 543  Bit Score: 40.35  E-value: 2.33e-03
                         10        20
                 ....*....|....*....|..
gi 392890832 313 GIKVNDACETSLPNVFACGDVC 334
Cdd:PRK06263 350 GIRINEDCETNIPGLFACGEVA 371
PRK05249 PRK05249
Si-specific NAD(P)(+) transhydrogenase;
285-378 2.93e-03

Si-specific NAD(P)(+) transhydrogenase;


Pssm-ID: 235373 [Multi-domain]  Cd Length: 461  Bit Score: 40.14  E-value: 2.93e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392890832 285 DIFIWAGGVTANSEvwAMNkmlqiTENSG--------IKVNDACETSLPNVFACGDVCALtttePStlwqqrqLWTQARQ 356
Cdd:PRK05249 262 DCLLYANGRTGNTD--GLN-----LENAGleadsrgqLKVNENYQTAVPHIYAVGDVIGF----PS-------LASASMD 323

                         90       100
                 ....*....|....*....|..
gi 392890832 357 QGEVCGRAMVaGVEEARMQNMY 378
Cdd:PRK05249 324 QGRIAAQHAV-GEATAHLIEDI 344
PRK06370 PRK06370
FAD-containing oxidoreductase;
313-339 3.02e-03

FAD-containing oxidoreductase;


Pssm-ID: 235787 [Multi-domain]  Cd Length: 463  Bit Score: 39.80  E-value: 3.02e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 392890832 313 GIKVNDACETSLPNVFACGDVC---ALTTT 339
Cdd:PRK06370 290 YIKVDDQLRTTNPGIYAAGDCNgrgAFTHT 319
PRK15317 PRK15317
alkyl hydroperoxide reductase subunit F; Provisional
 314-341 4.27e-03

alkyl hydroperoxide reductase subunit F; Provisional


Pssm-ID: 237942 [Multi-domain]  Cd Length: 517  Bit Score: 39.37  E-value: 4.27e-03
                         10        20
                 ....*....|....*....|....*...
gi 392890832 314 IKVNDACETSLPNVFACGDVcaltTTEP 341
Cdd:PRK15317 466 IIVDARGATSVPGVFAAGDC----TTVP 489
PRK11749 PRK11749
dihydropyrimidine dehydrogenase subunit A; Provisional
 285-333 7.16e-03

dihydropyrimidine dehydrogenase subunit A; Provisional


Pssm-ID: 236967 [Multi-domain]  Cd Length: 457  Bit Score: 38.62  E-value: 7.16e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 392890832 285 DIFIWAGGVTANSEVWAMNKMLQITENSGIKVNDA-CETSLPNVFACGDV 333
Cdd:PRK11749 377 DLVIKAIGQTPNPLILSTTPGLELNRWGTIIADDEtGRTSLPGVFAGGDI 426
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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