Peptidase M12A domain-containing protein [Caenorhabditis elegans]
zinc metalloprotease( domain architecture ID 1881)
zinc metalloprotease may be a member of the astacin-like protease family or the adamalysin/reprolysin-like protease family
List of domain hits
Name | Accession | Description | Interval | E-value | ||
ZnMc super family | cl00064 | Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major ... |
62-99 | 1.80e-03 | ||
Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which are involved in vertebrate development and disease. The actual alignment was detected with superfamily member cd04280: Pssm-ID: 469599 [Multi-domain] Cd Length: 180 Bit Score: 38.71 E-value: 1.80e-03
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Name | Accession | Description | Interval | E-value | ||
ZnMc_astacin_like | cd04280 | Zinc-dependent metalloprotease, astacin_like subfamily or peptidase family M12A, a group of ... |
62-99 | 1.80e-03 | ||
Zinc-dependent metalloprotease, astacin_like subfamily or peptidase family M12A, a group of zinc-dependent proteolytic enzymes with a HExxH zinc-binding site/active site. Members of this family may have an amino terminal propeptide, which is cleaved to yield the active protease domain, which is consequently always found at the N-terminus in multi-domain architectures. This family includes: astacin, a digestive enzyme from Crayfish; meprin, a multiple domain membrane component that is constructed from a homologous alpha and beta chain, proteins involved in (bone) morphogenesis, tolloid from drosophila, and the sea urchin SPAN protein, which may also play a role in development. Pssm-ID: 239807 [Multi-domain] Cd Length: 180 Bit Score: 38.71 E-value: 1.80e-03
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Name | Accession | Description | Interval | E-value | ||
ZnMc_astacin_like | cd04280 | Zinc-dependent metalloprotease, astacin_like subfamily or peptidase family M12A, a group of ... |
62-99 | 1.80e-03 | ||
Zinc-dependent metalloprotease, astacin_like subfamily or peptidase family M12A, a group of zinc-dependent proteolytic enzymes with a HExxH zinc-binding site/active site. Members of this family may have an amino terminal propeptide, which is cleaved to yield the active protease domain, which is consequently always found at the N-terminus in multi-domain architectures. This family includes: astacin, a digestive enzyme from Crayfish; meprin, a multiple domain membrane component that is constructed from a homologous alpha and beta chain, proteins involved in (bone) morphogenesis, tolloid from drosophila, and the sea urchin SPAN protein, which may also play a role in development. Pssm-ID: 239807 [Multi-domain] Cd Length: 180 Bit Score: 38.71 E-value: 1.80e-03
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Blast search parameters | ||||
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