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Conserved domains on  [gi|17534789|ref|NP_493708|]
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Fatty Acid/Retinol binding protein [Caenorhabditis elegans]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Gp-FAR-1 super family cl05414
Nematode fatty acid retinoid binding protein (Gp-FAR-1); Parasitic nematodes produce at least ...
 11-136 6.10e-18

Nematode fatty acid retinoid binding protein (Gp-FAR-1); Parasitic nematodes produce at least two structurally novel classes of small helix-rich retinol- and fatty-acid-binding proteins that have no counterparts in their plant or animal hosts and thus represent potential targets for new nematicides. Gp-FAR-1 is a member of the nematode-specific fatty-acid- and retinol-binding (FAR) family of proteins but localizes to the surface of the organizm, placing it in a strategic position for interaction with the host. Gp-FAR-1 functions as a broad-spectrum retinol- and fatty-acid-binding protein, and it is thought that it is involved in the evasion of primary host plant defence systems.


The actual alignment was detected with superfamily member pfam05823:

Pssm-ID: 399080  Cd Length: 142  Bit Score: 74.66  E-value: 6.10e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534789    11 KNFFPTEQLEFSSSITADEKPVLHEVFQKHSCFSQCGEMIDEVSKKHPELGKRLATVLEGNKKRLDGLSPAAVEYAKKLI 90
Cdd:pfam05823   3 KDLLPAEVVEALKNLTPEEKAILKEVFKNYKGYKNEDELIAALKEKSPSLGEKAEKLYAKLKAKVDKLSPEAKEFVEELI 82

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 17534789    91 HMVTTTLCSLTVGKPIDDADAKRL--HQ--EFQSLSSEDQAALRKNNPDI 136
Cdd:pfam05823  83 ATGRKLYAQVLAGEKPDPDELKQVacTIfnAYKALSPEAKAELEKTFPII 132
 
Name Accession Description Interval E-value
Gp-FAR-1 pfam05823
Nematode fatty acid retinoid binding protein (Gp-FAR-1); Parasitic nematodes produce at least ...
 11-136 6.10e-18

Nematode fatty acid retinoid binding protein (Gp-FAR-1); Parasitic nematodes produce at least two structurally novel classes of small helix-rich retinol- and fatty-acid-binding proteins that have no counterparts in their plant or animal hosts and thus represent potential targets for new nematicides. Gp-FAR-1 is a member of the nematode-specific fatty-acid- and retinol-binding (FAR) family of proteins but localizes to the surface of the organizm, placing it in a strategic position for interaction with the host. Gp-FAR-1 functions as a broad-spectrum retinol- and fatty-acid-binding protein, and it is thought that it is involved in the evasion of primary host plant defence systems.


Pssm-ID: 399080  Cd Length: 142  Bit Score: 74.66  E-value: 6.10e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534789    11 KNFFPTEQLEFSSSITADEKPVLHEVFQKHSCFSQCGEMIDEVSKKHPELGKRLATVLEGNKKRLDGLSPAAVEYAKKLI 90
Cdd:pfam05823   3 KDLLPAEVVEALKNLTPEEKAILKEVFKNYKGYKNEDELIAALKEKSPSLGEKAEKLYAKLKAKVDKLSPEAKEFVEELI 82

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 17534789    91 HMVTTTLCSLTVGKPIDDADAKRL--HQ--EFQSLSSEDQAALRKNNPDI 136
Cdd:pfam05823  83 ATGRKLYAQVLAGEKPDPDELKQVacTIfnAYKALSPEAKAELEKTFPII 132
 
Name Accession Description Interval E-value
Gp-FAR-1 pfam05823
Nematode fatty acid retinoid binding protein (Gp-FAR-1); Parasitic nematodes produce at least ...
 11-136 6.10e-18

Nematode fatty acid retinoid binding protein (Gp-FAR-1); Parasitic nematodes produce at least two structurally novel classes of small helix-rich retinol- and fatty-acid-binding proteins that have no counterparts in their plant or animal hosts and thus represent potential targets for new nematicides. Gp-FAR-1 is a member of the nematode-specific fatty-acid- and retinol-binding (FAR) family of proteins but localizes to the surface of the organizm, placing it in a strategic position for interaction with the host. Gp-FAR-1 functions as a broad-spectrum retinol- and fatty-acid-binding protein, and it is thought that it is involved in the evasion of primary host plant defence systems.


Pssm-ID: 399080  Cd Length: 142  Bit Score: 74.66  E-value: 6.10e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534789    11 KNFFPTEQLEFSSSITADEKPVLHEVFQKHSCFSQCGEMIDEVSKKHPELGKRLATVLEGNKKRLDGLSPAAVEYAKKLI 90
Cdd:pfam05823   3 KDLLPAEVVEALKNLTPEEKAILKEVFKNYKGYKNEDELIAALKEKSPSLGEKAEKLYAKLKAKVDKLSPEAKEFVEELI 82

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 17534789    91 HMVTTTLCSLTVGKPIDDADAKRL--HQ--EFQSLSSEDQAALRKNNPDI 136
Cdd:pfam05823  83 ATGRKLYAQVLAGEKPDPDELKQVacTIfnAYKALSPEAKAELEKTFPII 132
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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