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Conserved domains on  [gi|193202443|ref|NP_492205|]
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Nucleotide PPase [Caenorhabditis elegans]

Protein Classification

Maf family protein( domain architecture ID 10785471)

multicopy associated filamentation (Maf) family protein is involved in septum formation and also has a role as a house-cleaning NTP pyrophosphatase

CATH:  3.90.950.10
EC:  3.6.1.-
Gene Ontology:  GO:0009117|GO:0047429|GO:0009146|GO:0000166
PubMed:  24210219
SCOP:  4000520

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Maf COG0424
7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary ...
 6-196 2.49e-66

7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary metabolites biosynthesis, transport and catabolism];


:

Pssm-ID: 440193  Cd Length: 189  Bit Score: 201.42  E-value: 2.49e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443   6 IVLASQSPNRLKLLQQIGLEnVIVKVSNFEENLPKTLPVKQFVIETAKGKLTTIVEEMkrkeePYSVIIACDTVIEFNGE 85
Cdd:COG0424    3 LILASASPRRRELLEQLGLP-FEVVPPDIDETPLPGESPEELVLRLARAKAEAVAARL-----PDALVLGADTVVVLDGR 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443  86 IIGKPTDANDAKETLKRLRNNTHNVYTGMALHYHETDQYEEIiEKTIVHFGDIPDRVIDEYVKSGEPLKKAGSYGIGDFG 165
Cdd:COG0424   77 ILGKPADAEEARAMLRRLSGRTHRVHTGVALIDPGGRLWTRV-VTTRVTFRPLSDAEIEAYLATGEPLDKAGAYGIQGLG 155

                        170       180       190
                 ....*....|....*....|....*....|.
gi 193202443 166 AVFVRGIEGCMPNVVGLPLHRLHQALIAKNI 196
Cdd:COG0424  156 AALVERIEGSYSNVVGLPLIELLELLRELGV 186
 
Name Accession Description Interval E-value
Maf COG0424
7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary ...
 6-196 2.49e-66

7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440193  Cd Length: 189  Bit Score: 201.42  E-value: 2.49e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443   6 IVLASQSPNRLKLLQQIGLEnVIVKVSNFEENLPKTLPVKQFVIETAKGKLTTIVEEMkrkeePYSVIIACDTVIEFNGE 85
Cdd:COG0424    3 LILASASPRRRELLEQLGLP-FEVVPPDIDETPLPGESPEELVLRLARAKAEAVAARL-----PDALVLGADTVVVLDGR 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443  86 IIGKPTDANDAKETLKRLRNNTHNVYTGMALHYHETDQYEEIiEKTIVHFGDIPDRVIDEYVKSGEPLKKAGSYGIGDFG 165
Cdd:COG0424   77 ILGKPADAEEARAMLRRLSGRTHRVHTGVALIDPGGRLWTRV-VTTRVTFRPLSDAEIEAYLATGEPLDKAGAYGIQGLG 155

                        170       180       190
                 ....*....|....*....|....*....|.
gi 193202443 166 AVFVRGIEGCMPNVVGLPLHRLHQALIAKNI 196
Cdd:COG0424  156 AALVERIEGSYSNVVGLPLIELLELLRELGV 186
Maf cd00555
Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in ...
 6-191 5.23e-66

Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or nucleic acid-binding protein with structural similarity to the hypoxanthine/xanthine NTP pyrophosphatase Ham1 from Methanococcus jannaschii, RNase H from Escherichia coli, and some other nucleotide or RNA-binding proteins.


Pssm-ID: 238310  Cd Length: 180  Bit Score: 200.40  E-value: 5.23e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443   6 IVLASQSPNRLKLLQQIGLeNVIVKVSNFEENLPKTLPVKQFVIETAKGKLTTIVEEMKRKeepySVIIACDTVIEFNGE 85
Cdd:cd00555    1 LILASASPRRRELLEQLGI-PFEVVPSDIDETPIKGESPEDYVLRLAEAKAEAVAARLPPD----ALVIGADTVVVLDGR 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443  86 IIGKPTDANDAKETLKRLRNNTHNVYTGMALhYHETDQYEEIIEKTIVHFGDIPDRVIDEYVKSGEPLKKAGSYGIGDFG 165
Cdd:cd00555   76 ILGKPKDREEAREMLKRLSGRTHEVYTGVAL-IDPGGKLVTDVESTKVRFRELSDEEIEAYVASGEPLDKAGAYGIQGLG 154

                        170       180
                 ....*....|....*....|....*.
gi 193202443 166 AVFVRGIEGCMPNVVGLPLHRLHQAL 191
Cdd:cd00555  155 GALIERIEGDYSNVVGLPLPELLKLL 180
Maf pfam02545
Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and ...
 6-191 5.92e-65

Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and archaea.


Pssm-ID: 460586  Cd Length: 174  Bit Score: 197.63  E-value: 5.92e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443    6 IVLASQSPNRLKLLQQIGLEnVIVKVSNFEENLPK-TLPVKQFVIETAKGKLTTIVeemkrkeepysviIACDTVIEFng 84
Cdd:pfam02545   1 LILASASPRRRELLEQLGIE-FEVVPSDIDETPLKeDPAPEEYVLRLARAKAEALV-------------IGADTVVVL-- 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443   85 eIIGKPTDANDAKETLKRLRNNTHNVYTGMAL-HYHETDQYEEIIEKTIVHFGDIPDRVIDEYVKSGEPLKKAGSYGIGD 163
Cdd:pfam02545  65 -ILGKPKDEEEARAMLKRLSGRTHEVYTGVALiNPGGGTGGVSFVETTRVTFRPLSDEEIEAYVATGEPLDKAGAYGIQG 143

                         170       180
                  ....*....|....*....|....*...
gi 193202443  164 FGAVFVRGIEGCMPNVVGLPLHRLHQAL 191
Cdd:pfam02545 144 LGAALVERIEGDYSNVVGLPLIELLRLL 171
maf TIGR00172
MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A ...
 6-191 2.99e-51

MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A member of the family is found in the Archaeon Pyrococcus horikoshii and another in the round worm Caenorhabditis elegans. [Cellular processes, Cell division]


Pssm-ID: 129276  Cd Length: 183  Bit Score: 163.34  E-value: 2.99e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443    6 IVLASQSPNRLKLLQQIGLeNVIVKVSNFEENLPKTLPVKQFVIETAKGKLTTIVEEMkrkeePYSVIIACDTVIEFNGE 85
Cdd:TIGR00172   5 LILASQSPRRKELLEELGI-SFEQIVSEFDEKSLKTTSPRELVYRLAKEKAQAVAELL-----ADALIIGADTVVILDGE 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443   86 IIGKPTDANDAKETLKRLRNNTHNVYTGMAL--HYHETDQYEEiiekTIVHFGDIPDRVIDEYVKSGEPLKKAGSYGIGD 163
Cdd:TIGR00172  79 IYGKPKDKEEAAEFLRKLSGQEHEVYTAVALidSVHLLTFLDV----TKVHFRALDPEEIEKYVESGEPLEKAGAFGIEG 154

                         170       180
                  ....*....|....*....|....*...
gi 193202443  164 FGAVFVRGIEGCMPNVVGLPLHRLHQAL 191
Cdd:TIGR00172 155 FGAPLIKKIDGDYSNVVGLPLEKLLGAL 182
PRK00648 PRK00648
Maf-like protein; Reviewed
 2-196 4.06e-48

Maf-like protein; Reviewed


Pssm-ID: 234807  Cd Length: 191  Bit Score: 155.45  E-value: 4.06e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443   2 KEAIIVLASQSPNRLKLLQQIGLENVIVKVSNFEENLPKTLPVKQFVIETAKGKLTTIVEEMKrkeePYSVIIACDTVIE 81
Cdd:PRK00648   1 MKYKIILASSSPRRKEILEGFRIPFEVVPSPFVEESYPYSLDPEEITLELARLKAEAVRSDLF----PDELIITADTIVW 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443  82 FNGEIIGKPTDANDAKETLKRLRNNTHNVYTGMALhYHETDQyEEIIEKTIVHFGDIPDRVIDEYVKSGEPLKKAGSYGI 161
Cdd:PRK00648  77 YDGKVLGKPKDEEEAVEMLRTLSGKTHEVITGVCL-LHNGKL-LSGSETTQVTFRELSDEEIEYYIDTYKPLDKAGAYGI 154

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 193202443 162 GDFGAVFVRGIEGCMPNVVGLPLHRLHQALIAKNI 196
Cdd:PRK00648 155 QEWGGLIVKKIEGSYYNVMGLPIQTLYEELKELGI 189
 
Name Accession Description Interval E-value
Maf COG0424
7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary ...
 6-196 2.49e-66

7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440193  Cd Length: 189  Bit Score: 201.42  E-value: 2.49e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443   6 IVLASQSPNRLKLLQQIGLEnVIVKVSNFEENLPKTLPVKQFVIETAKGKLTTIVEEMkrkeePYSVIIACDTVIEFNGE 85
Cdd:COG0424    3 LILASASPRRRELLEQLGLP-FEVVPPDIDETPLPGESPEELVLRLARAKAEAVAARL-----PDALVLGADTVVVLDGR 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443  86 IIGKPTDANDAKETLKRLRNNTHNVYTGMALHYHETDQYEEIiEKTIVHFGDIPDRVIDEYVKSGEPLKKAGSYGIGDFG 165
Cdd:COG0424   77 ILGKPADAEEARAMLRRLSGRTHRVHTGVALIDPGGRLWTRV-VTTRVTFRPLSDAEIEAYLATGEPLDKAGAYGIQGLG 155

                        170       180       190
                 ....*....|....*....|....*....|.
gi 193202443 166 AVFVRGIEGCMPNVVGLPLHRLHQALIAKNI 196
Cdd:COG0424  156 AALVERIEGSYSNVVGLPLIELLELLRELGV 186
Maf cd00555
Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in ...
 6-191 5.23e-66

Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or nucleic acid-binding protein with structural similarity to the hypoxanthine/xanthine NTP pyrophosphatase Ham1 from Methanococcus jannaschii, RNase H from Escherichia coli, and some other nucleotide or RNA-binding proteins.


Pssm-ID: 238310  Cd Length: 180  Bit Score: 200.40  E-value: 5.23e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443   6 IVLASQSPNRLKLLQQIGLeNVIVKVSNFEENLPKTLPVKQFVIETAKGKLTTIVEEMKRKeepySVIIACDTVIEFNGE 85
Cdd:cd00555    1 LILASASPRRRELLEQLGI-PFEVVPSDIDETPIKGESPEDYVLRLAEAKAEAVAARLPPD----ALVIGADTVVVLDGR 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443  86 IIGKPTDANDAKETLKRLRNNTHNVYTGMALhYHETDQYEEIIEKTIVHFGDIPDRVIDEYVKSGEPLKKAGSYGIGDFG 165
Cdd:cd00555   76 ILGKPKDREEAREMLKRLSGRTHEVYTGVAL-IDPGGKLVTDVESTKVRFRELSDEEIEAYVASGEPLDKAGAYGIQGLG 154

                        170       180
                 ....*....|....*....|....*.
gi 193202443 166 AVFVRGIEGCMPNVVGLPLHRLHQAL 191
Cdd:cd00555  155 GALIERIEGDYSNVVGLPLPELLKLL 180
Maf pfam02545
Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and ...
 6-191 5.92e-65

Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and archaea.


Pssm-ID: 460586  Cd Length: 174  Bit Score: 197.63  E-value: 5.92e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443    6 IVLASQSPNRLKLLQQIGLEnVIVKVSNFEENLPK-TLPVKQFVIETAKGKLTTIVeemkrkeepysviIACDTVIEFng 84
Cdd:pfam02545   1 LILASASPRRRELLEQLGIE-FEVVPSDIDETPLKeDPAPEEYVLRLARAKAEALV-------------IGADTVVVL-- 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443   85 eIIGKPTDANDAKETLKRLRNNTHNVYTGMAL-HYHETDQYEEIIEKTIVHFGDIPDRVIDEYVKSGEPLKKAGSYGIGD 163
Cdd:pfam02545  65 -ILGKPKDEEEARAMLKRLSGRTHEVYTGVALiNPGGGTGGVSFVETTRVTFRPLSDEEIEAYVATGEPLDKAGAYGIQG 143

                         170       180
                  ....*....|....*....|....*...
gi 193202443  164 FGAVFVRGIEGCMPNVVGLPLHRLHQAL 191
Cdd:pfam02545 144 LGAALVERIEGDYSNVVGLPLIELLRLL 171
maf TIGR00172
MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A ...
 6-191 2.99e-51

MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A member of the family is found in the Archaeon Pyrococcus horikoshii and another in the round worm Caenorhabditis elegans. [Cellular processes, Cell division]


Pssm-ID: 129276  Cd Length: 183  Bit Score: 163.34  E-value: 2.99e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443    6 IVLASQSPNRLKLLQQIGLeNVIVKVSNFEENLPKTLPVKQFVIETAKGKLTTIVEEMkrkeePYSVIIACDTVIEFNGE 85
Cdd:TIGR00172   5 LILASQSPRRKELLEELGI-SFEQIVSEFDEKSLKTTSPRELVYRLAKEKAQAVAELL-----ADALIIGADTVVILDGE 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443   86 IIGKPTDANDAKETLKRLRNNTHNVYTGMAL--HYHETDQYEEiiekTIVHFGDIPDRVIDEYVKSGEPLKKAGSYGIGD 163
Cdd:TIGR00172  79 IYGKPKDKEEAAEFLRKLSGQEHEVYTAVALidSVHLLTFLDV----TKVHFRALDPEEIEKYVESGEPLEKAGAFGIEG 154

                         170       180
                  ....*....|....*....|....*...
gi 193202443  164 FGAVFVRGIEGCMPNVVGLPLHRLHQAL 191
Cdd:TIGR00172 155 FGAPLIKKIDGDYSNVVGLPLEKLLGAL 182
PRK00648 PRK00648
Maf-like protein; Reviewed
 2-196 4.06e-48

Maf-like protein; Reviewed


Pssm-ID: 234807  Cd Length: 191  Bit Score: 155.45  E-value: 4.06e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443   2 KEAIIVLASQSPNRLKLLQQIGLENVIVKVSNFEENLPKTLPVKQFVIETAKGKLTTIVEEMKrkeePYSVIIACDTVIE 81
Cdd:PRK00648   1 MKYKIILASSSPRRKEILEGFRIPFEVVPSPFVEESYPYSLDPEEITLELARLKAEAVRSDLF----PDELIITADTIVW 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443  82 FNGEIIGKPTDANDAKETLKRLRNNTHNVYTGMALhYHETDQyEEIIEKTIVHFGDIPDRVIDEYVKSGEPLKKAGSYGI 161
Cdd:PRK00648  77 YDGKVLGKPKDEEEAVEMLRTLSGKTHEVITGVCL-LHNGKL-LSGSETTQVTFRELSDEEIEYYIDTYKPLDKAGAYGI 154

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 193202443 162 GDFGAVFVRGIEGCMPNVVGLPLHRLHQALIAKNI 196
Cdd:PRK00648 155 QEWGGLIVKKIEGSYYNVMGLPIQTLYEELKELGI 189
PRK00078 PRK00078
Maf-like protein; Reviewed
 6-191 5.19e-48

Maf-like protein; Reviewed


Pssm-ID: 234618  Cd Length: 192  Bit Score: 155.27  E-value: 5.19e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443   6 IVLASQSPNRLKLLQQIgLENVIVKVSNFEENL-PKTLPVKQFVIETAKGKLTTIVEEMKRKEepySVIIACDTVIEFNG 84
Cdd:PRK00078   3 IILASASERRQELLKRI-LEDFQVIVSDFDESSvPFKGNIESYVMNLAEGKARSVSKKLDQES---SIVIGCDTIVAFNG 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443  85 EIIGKPTDANDAKETLKRLRNNTHNVYTGMALhyheTDQYEEIIEK----TIVHFGDIPDRVIDEYVKSGEPLKKAGSYG 160
Cdd:PRK00078  79 KVLGKPKDEEDAFEMLKALSGNEHEVYSGIAI----LDTKSNKIIKdfvcTEVKFSKLTDRQIRKYINTGEPMDKAGAYG 154

                        170       180       190
                 ....*....|....*....|....*....|.
gi 193202443 161 IGDFGAVFVRGIEGCMPNVVGLPLHRLHQAL 191
Cdd:PRK00078 155 IQGKGGVFVEEINGCYYNVVGLPLNKLYKML 185
PRK14365 PRK14365
Maf-like protein; Provisional
 6-191 1.39e-39

Maf-like protein; Provisional


Pssm-ID: 237690  Cd Length: 197  Bit Score: 133.79  E-value: 1.39e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443   6 IVLASQSPNRLKLLQQIGLENVIVKVSNFEENLPKTLPVKQFVIETAKGKLTTIVeemkrKEEPYSVIIACDTVIEFNGE 85
Cdd:PRK14365   4 IILASASPRRKELLKQLIGDNFLVYPSSYEEPPQPGLDPEELLLKHSLEKARDVA-----KHFDSGIIISADTSVFCNGE 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443  86 IIGKPTDANDAKETLKRLRNNTHNVYTGMALHYHETDQYEEIIEKTIVHFGDIPDRVIDEYVKSGEPLKKAGSYGIGDFG 165
Cdd:PRK14365  79 VLGKPASPENAEEMLEKLSGRKFLVITGLTVLDLDSGKEISEIESTDVWMTELSREQILAYVRTGEPLDKAGAFAIQGKG 158

                        170       180
                 ....*....|....*....|....*.
gi 193202443 166 AVFVRGIEGCMPNVVGLPLHRLHQAL 191
Cdd:PRK14365 159 AVLVEKIEGDFFNVVGLPLFRLGKIL 184
PRK14363 PRK14363
Maf-like protein; Provisional
 6-194 6.59e-37

Maf-like protein; Provisional


Pssm-ID: 184647  Cd Length: 204  Bit Score: 127.32  E-value: 6.59e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443   6 IVLASQSPNRLKLLQQIGLENVIVKVSNFEENLPKTlpvKQFVIETAKGKLTTIVEemKRKEEPySVIIACDTVIEFNGE 85
Cdd:PRK14363   3 IILASSSPRRRQLMELLGIEFEVEKPDVEEEFLESP---EETVRELSLRKAEWVFK--KRKEEE-ILVIGSDTVVVLDGN 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443  86 IIGKPTDANDAKETLKRLRNNTHNVYTGMALHYHETDqyEEIIEKTIVHFGDIPDRVIDEYVKSGEPLKKAGSYGIGDFG 165
Cdd:PRK14363  77 ILGKPESLEEAKGMLKKLSGRWHVVYTGVAFVSSETK--DVIVSSTKVRFRELPESVIDYYVEKYRPLDKAGAYGIQDFA 154

                        170       180
                 ....*....|....*....|....*....
gi 193202443 166 AVFVRGIEGCMPNVVGLPLHRLHQALIAK 194
Cdd:PRK14363 155 AVFVEKIEGDFFTVVGFPLGMVWQYLYEK 183
PRK14368 PRK14368
Maf-like protein; Provisional
 1-191 5.39e-36

Maf-like protein; Provisional


Pssm-ID: 237693  Cd Length: 193  Bit Score: 124.51  E-value: 5.39e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443   1 MKEAIIVLASQSPNRLKLLQQIGLENVIVKVSNFEENLPKTLPVkQFVIETAKGKLTTIVEemkRKEEPYsvIIACDTVI 80
Cdd:PRK14368   2 MANSPIVLASASPRRSELLASAGIEFDVVPADIPEEPLPGEEPV-DHVLRLAREKARAAAA---LAEGRF--FIGADTIV 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443  81 EFNGEIIGKPTDANDAKETLKRLRNNTHNVYTGMALHYHETDQYEEIIEKTIVHFGDIPDRVIDEYVKSGEPLKKAGSYG 160
Cdd:PRK14368  76 VCDGEIMGKPKDEADAVRMLKKLSGVPHEVITGFAVYDRERDGCVTKAVRTKVFFKPLRDEEIRDYIATGCPMDKAGAYA 155

                        170       180       190
                 ....*....|....*....|....*....|.
gi 193202443 161 IGDFGAVFVRGIEGCMPNVVGLPLHRLHQAL 191
Cdd:PRK14368 156 IQGGAAHMVRKIDGSYTNVVGLPLCEVVEAL 186
PRK14361 PRK14361
Maf-like protein; Provisional
 6-184 3.98e-32

Maf-like protein; Provisional


Pssm-ID: 172837  Cd Length: 187  Bit Score: 114.26  E-value: 3.98e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443   6 IVLASQSPNRLKLLQQIGLENVIVkVSNFEENLPKTLPVKqfvietAKGKLTTIVEEMKRKEEPYSVIIACDTVIEFNGE 85
Cdd:PRK14361   1 VILASGSPRRRELLENLGVPFQVV-VSGEAEDSTETDPAR------LAAELALLKARAVARLHPDAVVIAADTVVALGGV 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443  86 IIGKPTDANDAKETLKRLRNNTHNVYTGMALHYHETDQYEeiIEKTIVHFGDIPDRVIDEYVKSGEPLKKAGSYGIGDFG 165
Cdd:PRK14361  74 LLAKPADEAENEAFLRVLSGRTHQVYTGVAVLSRGTEQVG--VERTDVTFRALTAAEISFYARSGEGLDKAGGYGIQGVG 151

                        170
                 ....*....|....*....
gi 193202443 166 AVFVRGIEGCMPNVVGLPL 184
Cdd:PRK14361 152 MALVSRVEGDYSNVVGFPL 170
PRK14364 PRK14364
Maf-like protein; Provisional
 8-191 2.58e-31

Maf-like protein; Provisional


Pssm-ID: 184648  Cd Length: 181  Bit Score: 112.02  E-value: 2.58e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443   8 LASQSPNRLKLLQQIGLENVIVKvSNFEENLPKTLPVKQFVIETAKGKLTTIVEEMkrkeePYSVIIACDTVIEFNGEII 87
Cdd:PRK14364   1 LASSSPRRRELLQQLGLNFEIYS-PDIDESVHEGELVHQYVERLAREKAQAVLNIF-----PDSVIIAADTSLGLDGQII 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443  88 GKPTDANDAKETLKRLRNNTHNVYTGMALHYHEtdQYEEIIEKTIVHFGDIPDRVIDEYVKSGEPLKKAGSYGIGDFGAV 167
Cdd:PRK14364  75 GKPDSKQHAFDIWKQLSGRWHDVFSGICIATQQ--QILSQVVQTQVEFASLTTQDMEDYWATGEPVGKAGAYAIQGIASQ 152

                        170       180
                 ....*....|....*....|....
gi 193202443 168 FVRGIEGCMPNVVGLPLHRLHQAL 191
Cdd:PRK14364 153 YIPKIQGSYSNVVGLPLYEFSQLF 176
PRK14362 PRK14362
Maf-like protein; Provisional
 6-197 6.56e-31

Maf-like protein; Provisional


Pssm-ID: 172838  Cd Length: 207  Bit Score: 111.88  E-value: 6.56e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443   6 IVLASQSPNRLKLLQQIGLE-NVIVKVSNFEENLPKTLPVkQFVIETAKGKLTTIVeemkrKEEPYSVIIACDTVIEFNG 84
Cdd:PRK14362  14 VVLASGSPRRREFLEQMGLPfEVILPGAAEPSPIEGEQPE-AYARRAAEAKARAVA-----ADHAGRLVIAADTVVALDG 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443  85 EIIGKPTDANDAKETLKRLRNNTHNVYTGMALHYHETDQyEEIIEKTIVHFGDIPDRVIDEYVKSGEPLKKAGSYGIGDF 164
Cdd:PRK14362  88 MILGKPADRADALSMLRRLAGRTHEVVSACCVVLPDGGR-EVFHAITRVTMWDWPEAALAAYVATGEPSDKAGAYGIQGI 166

                        170       180       190
                 ....*....|....*....|....*....|...
gi 193202443 165 GAVFVRGIEGCMPNVVGLPLHRLHQALIAKNIL 197
Cdd:PRK14362 167 GAFLVRSIEGSWSNVVGLPVAELTALLLRRGVI 199
Maf_Ham1 cd00985
Maf_Ham1. Maf, a nucleotide binding protein, has been implicated in inhibition of septum ...
 6-135 2.13e-27

Maf_Ham1. Maf, a nucleotide binding protein, has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea. A Ham1-related protein from Methanococcus jannaschii is a novel NTPase that has been shown to hydrolyze nonstandard nucleotides, such as hypoxanthine/xanthine NTP, but not standard nucleotides.


Pssm-ID: 238485  Cd Length: 131  Bit Score: 100.27  E-value: 2.13e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443   6 IVLASQSPNRLKLLQQIGLENVIVKVSNFEENLPKTLPVkQFVIETAKGKLTTIVEEMkrkeePYSVIIACDTVIEFNGE 85
Cdd:cd00985    1 LILASGSPRRLEELKQIGGIEFEVLPSDIDETGLKGEPE-DTVEELALLKARAVAERL-----PDAPVIADDTGLVVDGR 74

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 193202443  86 IIGKPTDANDAKETLKRLRNNTHNVYTGMALhYHETDQYEEIIEKTIVHF 135
Cdd:cd00985   75 PGGKPARFAEALEMLRGLSGRTAEFVTAVAL-VDPDGKIITFEGETEGKI 123
PRK01441 PRK01441
Maf-like protein; Reviewed
 6-185 3.44e-24

Maf-like protein; Reviewed


Pssm-ID: 167232  Cd Length: 207  Bit Score: 94.40  E-value: 3.44e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443   6 IVLASQSPNRLKLLQQIGLENVIVKVSNFEEN-----LPKTLpVKQFVIETAKGKLTTIVEEMKRKEepySVIIACDTVI 80
Cdd:PRK01441   7 LVLASGSPRRVELLNQAGIEPDRLMPADIDETpkraeHPRSL-ARRLSREKAEAALEALQGDDDWRG---AYILAADTVV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443  81 EFNGEIIGKPTDANDAKETLKRLRNNTHNVYTGMALHYHETDQYEEIIEkTIVHFGDIPDRVIDEYVKSGEPLKKAGSYG 160
Cdd:PRK01441  83 AVGRRILPKAELVDEASQCLRLLSGRNHRVYTGVCLVTPDGKLRQKLVE-TRVRFKRLSREDIEAYLASGEWRGKAGGYA 161

                        170       180
                 ....*....|....*....|....*
gi 193202443 161 IGDFGAVFVRGIEGCMPNVVGLPLH 185
Cdd:PRK01441 162 IQGIAGSFVVKLVGSYTNVVGLPLY 186
PRK14367 PRK14367
Maf-like protein; Provisional
 6-185 3.53e-24

Maf-like protein; Provisional


Pssm-ID: 237692  Cd Length: 202  Bit Score: 94.36  E-value: 3.53e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443   6 IVLASQSPNRLKLLQQIGLEnvIVKV-SNFEENLPKTLPVKQFVIETAKGK----LTTIVEemKRKEEPYSVIIACDTVI 80
Cdd:PRK14367   4 LYLGSNSPRRMEILTQLGYR--VVKLpAGIDETVKAGETPARYVQRMAEEKnrtaLTLFCE--TNGTMPDFPLITADTCV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443  81 EFNGEIIGKPTDANDAKETLKRLRNNTHNVYTGMALHYHetDQYEEIIEKTIVHFGDIPDRVIDEYVKSGEPLKKAGSYG 160
Cdd:PRK14367  80 VSDGIILGKPRSQAEAIEFLNRLSGKQHTVLTAVCIHYR--GKTSSRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYA 157

                        170       180
                 ....*....|....*....|....*
gi 193202443 161 IGDFGAVFVRGIEGCMPNVVGLPLH 185
Cdd:PRK14367 158 VQGIGGIFIQSIEGSFSGIMGLPVY 182
PRK14366 PRK14366
Maf-like protein; Provisional
 6-185 3.79e-22

Maf-like protein; Provisional


Pssm-ID: 237691  Cd Length: 195  Bit Score: 88.70  E-value: 3.79e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443   6 IVLASQSPNRLKLLQQIGLENVIVKVSNFEEN-LPKTLPvKQFVIETAKGKLTTIveemkRKEEPYSVIIACDTVIEFNG 84
Cdd:PRK14366   7 LILASSSKQRLALLEQIGVVPGEIVSPDIDESpLKKELP-KDYSIRMAKEKAEKV-----QSLRPDKFVLGADTVVCCGR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443  85 EIIGKPTDANDAKETLKRLRNNTHNVYTGMALHYHETDQYEEIIeKTIVHFGDIPDRVIDEYVKSGEPLKKAGSYGIGDF 164
Cdd:PRK14366  81 RILLKAETEEQAEEYLELLSGRRHRVYTSVCLYTPGGKLHIRSV-VTVVKFKRLSKQEIKYYIASGEWKGKAGGCNIQGL 159

                        170       180
                 ....*....|....*....|.
gi 193202443 165 GAVFVRGIEGCMPNVVGLPLH 185
Cdd:PRK14366 160 AGKFVLSINGSYSSIIGLPLH 180
PRK04694 PRK04694
Maf-like protein; Reviewed
 5-193 3.90e-22

Maf-like protein; Reviewed


Pssm-ID: 179873  Cd Length: 190  Bit Score: 88.48  E-value: 3.90e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443   5 IIVLASQSPNRLKLLQQIGLENVIVKVSNFEENLPKTLP---VKQFVIETAKGKLTTIveemkRKEEPYSVIIACDTVIE 81
Cdd:PRK04694   1 MLYLASRSPRRRELLQRLDVPFQTLQLDVPEVRAADESPdhyVQRVALEKAHAGLALV-----QAADADAIVLGSDTEVV 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443  82 FNGEIIGKPTDANDAKETLKRLRNNTHNVYTGMALHYHETDQYEEIIEKTiVHFGDIPDRVIDEYVKSGEPLKKAGSYGI 161
Cdd:PRK04694  76 LGERVFGKPVDVDDAIAMLRALSGRTHQVLTAVVLVCAQRAPAQALVVSE-VTFDLLDDAQIAAYAASGEPMGKAGAYAI 154

                        170       180       190
                 ....*....|....*....|....*....|..
gi 193202443 162 GDFGAVFVRGIEGCMPNVVGLPLHRLHQALIA 193
Cdd:PRK04694 155 QGRAERFIRHLSGSYSGVMGLPLYQTSQLLTA 186
PRK04056 PRK04056
septum formation inhibitor Maf;
6-164 1.98e-17

septum formation inhibitor Maf;


Pssm-ID: 179732  Cd Length: 180  Bit Score: 75.77  E-value: 1.98e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443   6 IVLASQSPNRLKLLQQIGLEnVIVKVSNFEENLPKTLPVKQFVIETAKGKLTTIVeemKRKEEPYSVIIAcDTVIEFNGE 85
Cdd:PRK04056   2 IILASSSSTRANLLKEAGIE-FEQKSLDFDEESIKKTSPKEFVYLAVKGKLEQFL---KKYGNECNLLVA-DSVVSCGNK 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193202443  86 IIGKPTDANDAKETLKRLRNNTHNVYTGMALhyhETDQYEEI-IEKTIVHFGDIPDRVIDEYVKSGEPLKKAGSYGIGDF 164
Cdd:PRK04056  77 ILRKAKDKEEAREMLKLQSGNEISVLTCMIL---KSPEKEWLdLSVTTYRFKKFDEDDLEKYLESGLWQGKAGACMVEGF 153
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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