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Conserved domains on  [gi|32564428|ref|NP_491494|]
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Tetratricopeptide repeat protein 30 homolog [Caenorhabditis elegans]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11459274)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 24-215 2.27e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 58.97  E-value: 2.27e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428  24 KFNDAIRILQYQHERNPKNLAALSLLAYCYYYTQDFMNAADCYSQLSYNFPQYSQYKLYHAQSLYNAFRPADALAVvsmi 103
Cdd:COG2956  91 LLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEA---- 166

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428 104 qdenllnesvkLEAAIKYQeddlvncrilveqlpENDAAVIINTACIDYKEGNYEEALKKFNEATEFSGYQSGLAYSIAL 183
Cdd:COG2956 167 -----------LEKALKLD---------------PDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAE 220

                       170       180       190
                ....*....|....*....|....*....|..
gi 32564428 184 CHYRRGDYDSALKLISEIINRGVKDHPEFNIG 215
Cdd:COG2956 221 LYEKLGDPEEALELLRKALELDPSDDLLLALA 252
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 133-332 1.81e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 40.87  E-value: 1.81e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428 133 VEQLPENDAAVIINTACIDYKEGNYEEALKKFNEATEFSGYQSGLAYSIALCHYRRGDYDSALKLISEIINRGVKDhpef 212
Cdd:COG2956  34 ALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDD---- 109

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428 213 nigmvtegidvnfiqntqklhesalIEAFNLKFAIYYRTKDFKAAKESLTDMPPRNEHDADpiTLHNLA-ISNANSDFGD 291
Cdd:COG2956 110 -------------------------AEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAH--AYCELAeLYLEQGDYDE 162

                       170       180       190       200
                ....*....|....*....|....*....|....*....|.
gi 32564428 292 SSAKLQFLLGINPFPQETFANLLFLYCKNDYFGLAADVLAE 332
Cdd:COG2956 163 AIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALER 203
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 24-215 2.27e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 58.97  E-value: 2.27e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428  24 KFNDAIRILQYQHERNPKNLAALSLLAYCYYYTQDFMNAADCYSQLSYNFPQYSQYKLYHAQSLYNAFRPADALAVvsmi 103
Cdd:COG2956  91 LLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEA---- 166

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428 104 qdenllnesvkLEAAIKYQeddlvncrilveqlpENDAAVIINTACIDYKEGNYEEALKKFNEATEFSGYQSGLAYSIAL 183
Cdd:COG2956 167 -----------LEKALKLD---------------PDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAE 220

                       170       180       190
                ....*....|....*....|....*....|..
gi 32564428 184 CHYRRGDYDSALKLISEIINRGVKDHPEFNIG 215
Cdd:COG2956 221 LYEKLGDPEEALELLRKALELDPSDDLLLALA 252
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 24-272 2.52e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.30  E-value: 2.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428    24 KFNDAIRILQYQHERNPKNLAA-LSLLAYCYYYTQDFMNAADCYSQLSYNFPQYSQYKLYHAQSLYNAFRPADALAVVSM 102
Cdd:TIGR02917 105 KFQQVLDELPGKTLLDDEGAAElLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDE 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428   103 IQDEN-------LLNESVKL------EAAIKYQEddlvncrilVEQLPENDAAVIINTACIDYKEGNYEEALKKFNEATE 169
Cdd:TIGR02917 185 VLTADpgnvdalLLKGDLLLslgnieLALAAYRK---------AIALRPNNIAVLLALATILIEAGEFEEAEKHADALLK 255

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428   170 FSGYQSGLAYSIALCHYRRGDYDSALklisEIINRGVKDHPEFNIGMVTEGIdvnfIQNTQKLHESAL------------ 237
Cdd:TIGR02917 256 KAPNSPLAHYLKALVDFQKKNYEDAR----ETLQDALKSAPEYLPALLLAGA----SEYQLGNLEQAYqylnqilkyapn 327

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 32564428   238 -IEAFNLKFAIYYRTKDFKAAKESLTDMPPRNEHDA 272
Cdd:TIGR02917 328 sHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDP 363
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 133-332 1.81e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 40.87  E-value: 1.81e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428 133 VEQLPENDAAVIINTACIDYKEGNYEEALKKFNEATEFSGYQSGLAYSIALCHYRRGDYDSALKLISEIINRGVKDhpef 212
Cdd:COG2956  34 ALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDD---- 109

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428 213 nigmvtegidvnfiqntqklhesalIEAFNLKFAIYYRTKDFKAAKESLTDMPPRNEHDADpiTLHNLA-ISNANSDFGD 291
Cdd:COG2956 110 -------------------------AEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAH--AYCELAeLYLEQGDYDE 162

                       170       180       190       200
                ....*....|....*....|....*....|....*....|.
gi 32564428 292 SSAKLQFLLGINPFPQETFANLLFLYCKNDYFGLAADVLAE 332
Cdd:COG2956 163 AIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALER 203
TPR_19 pfam14559
Tetratricopeptide repeat;
22-85 7.68e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 35.25  E-value: 7.68e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 32564428    22 EHKFNDAIRILQYQHERNPKNLAALSLLAYCYYYTQDFMNAADCYSQLSYNFPQYSQYKLYHAQ 85
Cdd:pfam14559   1 EGDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAK 64
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 24-215 2.27e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 58.97  E-value: 2.27e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428  24 KFNDAIRILQYQHERNPKNLAALSLLAYCYYYTQDFMNAADCYSQLSYNFPQYSQYKLYHAQSLYNAFRPADALAVvsmi 103
Cdd:COG2956  91 LLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEA---- 166

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428 104 qdenllnesvkLEAAIKYQeddlvncrilveqlpENDAAVIINTACIDYKEGNYEEALKKFNEATEFSGYQSGLAYSIAL 183
Cdd:COG2956 167 -----------LEKALKLD---------------PDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAE 220

                       170       180       190
                ....*....|....*....|....*....|..
gi 32564428 184 CHYRRGDYDSALKLISEIINRGVKDHPEFNIG 215
Cdd:COG2956 221 LYEKLGDPEEALELLRKALELDPSDDLLLALA 252
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 22-204 7.04e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 51.27  E-value: 7.04e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428  22 EHKFNDAIRILQYQHERNPKNLAALSLLAYCYYYTQDFMNAADCYSQLSYNFPQYSQYKLYHAQSLYNAFRPADALAVVS 101
Cdd:COG2956  21 NGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLE 100

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428 102 MIQDENLLNESVKLE-AAIKYQEDDLVNCRILVEQLPE---NDAAVIINTACIDYKEGNYEEALKKFNEATEFSGYQSGL 177
Cdd:COG2956 101 KLLELDPDDAEALRLlAEIYEQEGDWEKAIEVLERLLKlgpENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARA 180

                       170       180
                ....*....|....*....|....*..
gi 32564428 178 AYSIALCHYRRGDYDSALKLISEIINR 204
Cdd:COG2956 181 LLLLAELYLEQGDYEEAIAALERALEQ 207
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
17-211 1.26e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 50.01  E-value: 1.26e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428  17 YTLIHEHKFNDAIRILQYQHERNPKNLAALSLLAYCYYYTQDFMNAADCYSQLSYNFPQYSQYKLYHAQSLYNAFRPADA 96
Cdd:COG0457  16 LAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEA 95

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428  97 LAVvsmiqdenllnesvkLEAAIkyqeddlvncrilveQLPENDAAVIINTACIDYKEGNYEEALKKFNEATEFSGYQSG 176
Cdd:COG0457  96 LED---------------YDKAL---------------ELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDAD 145

                       170       180       190
                ....*....|....*....|....*....|....*
gi 32564428 177 LAYSIALCHYRRGDYDSALKLISEIINRGVKDHPE 211
Cdd:COG0457 146 ALYNLGIALEKLGRYEEALELLEKLEAAALAALLA 180
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 16-169 3.19e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 50.38  E-value: 3.19e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428  16 IYTLIHEHKFNDAIRILQYQHERNPKNLAALSLLAYCYYYTQDFMNAADCYSQ-LSYNfPQYSQYKLYHAQSLYNAFRPA 94
Cdd:COG3914  85 ALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRaLALN-PDFAEAYLNLGEALRRLGRLE 163

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 32564428  95 DALAvvsmiqdenllnesvkleaaikyqeddlvNCRILVEQLPeNDAAVIINTACIDYKEGNYEEALKKFNEATE 169
Cdd:COG3914 164 EAIA-----------------------------ALRRALELDP-DNAEALNNLGNALQDLGRLEEAIAAYRRALE 208
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
37-202 4.50e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 48.46  E-value: 4.50e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428  37 ERNPKNLAALSLLAYCYYYTQDFMNAADCYSQLSYNFPQYSQYKLYHAQSLYNAFRPADALAVvsmiqdenllnesvkLE 116
Cdd:COG0457   2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALAD---------------YE 66

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428 117 AAIKYQEDDlvncrilveqlpendAAVIINTACIDYKEGNYEEALKKFNEATEFSGYQSGLAYSIALCHYRRGDYDSALK 196
Cdd:COG0457  67 QALELDPDD---------------AEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIE 131


                ....*.
gi 32564428 197 LISEII 202
Cdd:COG0457 132 AYERAL 137
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 24-167 9.76e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 42.87  E-value: 9.76e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428  24 KFNDAIRILQYQHERNPKNLAALSLLAYCYYYTQDFMNAADCYSQLSYNFPQYSQYKLYHAQSLYNAFRPADALAVvsmi 103
Cdd:COG4783  19 DYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALAL---- 94

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 32564428 104 qdenllnesvkLEAAIKYQEDdlvncrilveqlpenDAAVIINTACIDYKEGNYEEALKKFNEA 167
Cdd:COG4783  95 -----------LEKALKLDPE---------------HPEAYLRLARAYRALGRPDEAIAALEKA 132
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 27-145 1.05e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 42.30  E-value: 1.05e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428  27 DAIRILQYQHERNPKNLAALSLLAYCYYYTQDFMNAADCYSQLSYNFPQYSQYKLYHAQSLYNAFRPADALAvvsmiqde 106
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEE-------- 72

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|...
gi 32564428 107 nLLNESVKLE----------AAIKYQEDD----LVNCRILVEQLPENDAAVII 145
Cdd:COG4235  73 -LLERALALDpdnpealyllGLAAFQQGDyaeaIAAWQKLLALLPADAPARLL 124
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 117-212 1.07e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 42.49  E-value: 1.07e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428 117 AAIKYQEDDLVNCRILVEQL----PENDAAvIINTACIDYKEGNYEEALKKFNEATEFSGYQSGLAYSIALCHYRRGDYD 192
Cdd:COG4783  11 AQALLLAGDYDEAEALLEKAleldPDNPEA-FALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYD 89

                        90       100
                ....*....|....*....|
gi 32564428 193 SALKLISEIINRGvKDHPEF 212
Cdd:COG4783  90 EALALLEKALKLD-PEHPEA 108
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 24-272 2.52e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.30  E-value: 2.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428    24 KFNDAIRILQYQHERNPKNLAA-LSLLAYCYYYTQDFMNAADCYSQLSYNFPQYSQYKLYHAQSLYNAFRPADALAVVSM 102
Cdd:TIGR02917 105 KFQQVLDELPGKTLLDDEGAAElLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDE 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428   103 IQDEN-------LLNESVKL------EAAIKYQEddlvncrilVEQLPENDAAVIINTACIDYKEGNYEEALKKFNEATE 169
Cdd:TIGR02917 185 VLTADpgnvdalLLKGDLLLslgnieLALAAYRK---------AIALRPNNIAVLLALATILIEAGEFEEAEKHADALLK 255

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428   170 FSGYQSGLAYSIALCHYRRGDYDSALklisEIINRGVKDHPEFNIGMVTEGIdvnfIQNTQKLHESAL------------ 237
Cdd:TIGR02917 256 KAPNSPLAHYLKALVDFQKKNYEDAR----ETLQDALKSAPEYLPALLLAGA----SEYQLGNLEQAYqylnqilkyapn 327

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 32564428   238 -IEAFNLKFAIYYRTKDFKAAKESLTDMPPRNEHDA 272
Cdd:TIGR02917 328 sHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDP 363
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 62-204 4.36e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 41.48  E-value: 4.36e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428  62 AADCYSQLSYNFPQYSQYKLYHAQSLYNAFRPADALAVVSMIQDENLLNESVKLEAAIKYqeddlvnCRILVEQLPeNDA 141
Cdd:COG5010  17 LTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLAL-------LEQALQLDP-NNP 88

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 32564428 142 AVIINTACIDYKEGNYEEALKKFNEATEFSGYQSGLAYSIALCHYRRGDYDSALKLISEIINR 204
Cdd:COG5010  89 ELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGT 151
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 133-332 1.81e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 40.87  E-value: 1.81e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428 133 VEQLPENDAAVIINTACIDYKEGNYEEALKKFNEATEFSGYQSGLAYSIALCHYRRGDYDSALKLISEIINRGVKDhpef 212
Cdd:COG2956  34 ALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDD---- 109

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428 213 nigmvtegidvnfiqntqklhesalIEAFNLKFAIYYRTKDFKAAKESLTDMPPRNEHDADpiTLHNLA-ISNANSDFGD 291
Cdd:COG2956 110 -------------------------AEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAH--AYCELAeLYLEQGDYDE 162

                       170       180       190       200
                ....*....|....*....|....*....|....*....|.
gi 32564428 292 SSAKLQFLLGINPFPQETFANLLFLYCKNDYFGLAADVLAE 332
Cdd:COG2956 163 AIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALER 203
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 18-69 4.90e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 37.68  E-value: 4.90e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|..
gi 32564428  18 TLIHEHKFNDAIRILQYQHERNPKNLAALSLLAYCYYYTQDFMNAADCYSQL 69
Cdd:COG4235  60 ALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKL 111
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
75-202 5.22e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 39.13  E-value: 5.22e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428  75 QYSQYKLYHAQSLYNAFRPADALAVVSMiqDENLLNESVKLEAAIKYQEddlvncRILVEQLPENDAAVIINTACIDYKE 154
Cdd:COG4785  15 AAAAASKAAILLAALLFAAVLALAIALA--DLALALAAAALAAAALAAE------RIDRALALPDLAQLYYERGVAYDSL 86

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*...
gi 32564428 155 GNYEEALKKFNEATEFSGYQSGLAYSIALCHYRRGDYDSALKLISEII 202
Cdd:COG4785  87 GDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRAL 134
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 17-99 5.99e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 37.48  E-value: 5.99e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428  17 YTLIHEHKFNDAIRILQYQHERNPKNLAALSLLAYCYYYTQDFMNAADCYSQLSYNFPQYSQYKLYHAQSLYNAFRPADA 96
Cdd:COG4783  46 EILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEA 125


                ...
gi 32564428  97 LAV 99
Cdd:COG4783 126 IAA 128
TPR_19 pfam14559
Tetratricopeptide repeat;
22-85 7.68e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 35.25  E-value: 7.68e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 32564428    22 EHKFNDAIRILQYQHERNPKNLAALSLLAYCYYYTQDFMNAADCYSQLSYNFPQYSQYKLYHAQ 85
Cdd:pfam14559   1 EGDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAK 64
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 16-99 8.08e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 37.63  E-value: 8.08e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428  16 IYTLIHEHKFNDAIRILQYQHERNPKNLAALSLLAYCYYYTQDFMNAADCYSQLSYNFPQYSQYKLYHAQSLYNAFRPAD 95
Cdd:COG5010  61 DNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDE 140


                ....
gi 32564428  96 ALAV 99
Cdd:COG5010 141 AKAA 144
BamD COG4105
Outer membrane protein assembly factor BamD, BamD/ComL family [Cell wall/membrane/envelope ...
 126-202 8.59e-03

Outer membrane protein assembly factor BamD, BamD/ComL family [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443281 [Multi-domain]  Cd Length: 254  Bit Score: 38.32  E-value: 8.59e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32564428 126 LVNCRILVEQLPENDAAVIINTACIDYKEGNYEEALKKFNEATE---FSGYQSGLAYSIALCHYRRGDYDSALKLISEII 202
Cdd:COG4105  17 LAGCSSFKKALKSWDAEELYEEAKEALEKGDYEKAIKLFEELEPrypGSPYAEQAQLMLAYAYYKQGDYEEAIAAADRFI 96
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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