|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02900 |
PLN02900 |
alanyl-tRNA synthetase |
5-965 |
0e+00 |
|
alanyl-tRNA synthetase
Pssm-ID: 215487 [Multi-domain] Cd Length: 936 Bit Score: 1181.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 5 TASEVRSTFINFFrEKKEHTYVHSSSVIPHDDPTLLFANAGMNQFKPLFLGIADPNSDLAKLKRAVNTQKCIRAGGKHND 84
Cdd:PLN02900 12 PGDRIRRTFLSFF-ESKGHTFLPSSPLVPVDDPTLLFTNAGMNQFKPIFLGTADPNTPLRKLPRATNTQKCIRAGGKHND 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 85 LDDVGKDVYHHTYFEMLGNWSFGDYFKKEIITWAWELLTTVYGIPAERLYVSVFGGDEAngVPADSEARDIWRSVgVPDE 164
Cdd:PLN02900 91 LDDVGKDTYHHTFFEMLGNWSFGDYFKKEAIGWAWELLTKVYGLPADRLYATYFGGDEK--QAPDDEARAIWLDY-LPEE 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 165 RILNFGMKDNFWEMGDVGPCGPCSEIHYDRIGNRDASHLVNADDPMVVEIWNLVFIQFNREEGGVLKPLPAKHIDCGLGL 244
Cdd:PLN02900 168 RVLPFGCKDNFWEMGDTGPCGPCSEIHYDRIGERDAADLVNNDDPRFIEIWNLVFIQFNREADGSLKPLPAKHVDTGMGL 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 245 ERLIAVMQDKTSNYDTDIFQPIFEAIHKGSGVRAYTGFIGDEDKDGVDMAYRVVADHVRTLTIALSDGGRPDNSGRGYVL 324
Cdd:PLN02900 248 ERLASILQNKPSNYDTDLFMPIFDAIQEATGARPYAGKVGAEDDDRVDMAYRVVADHIRTLSFAIADGVVPSNEGRGYVL 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 325 RRILRRGVRYASEKLNAQPGFFASLVPVVISILGETFPELSRDPVTVMDIINDEEKQFLKTLSRGRVLFQRAVQS-LPEG 403
Cdd:PLN02900 328 RRLLRRAVRYGRLLLGAEEGFFPALVEVVVELSGDVFPEVKKNEKRITEIIAEEELSFGKTLEKGIEKFKKALAAaKANG 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 404 TMTFPGDVSWRLYDTYGFPADLTQLMAEEKGLSVD----NTAFEEARRKAIETSSAGTGKfrdTLDLDVHALAELQQKGV 479
Cdd:PLN02900 408 GPVLSGKDAFLLYDTYGFPVDLTELMAEERGVTVDmegfEAAMEEARERSRAAHLKAGGG---AIELAAEATSWLQKQGV 484
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 480 PTTDDSPKYAYtftgegsdavykFEPCVGKILAIRRDGKFVDQLAAGEEGAILLDRTNFYAEQGGQIYDVGVLTKVNDES 559
Cdd:PLN02900 485 AATDDFLKYDW------------LSDHEAVVKAILTGGGFVESVSEGDEVGIVLDKTSFYAESGGQIGDTGVLEGSGGAV 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 560 neFNVSNCQVRGGYIVLVGS-AEGSFSVGDQVNERFDEDRKQLIMKNHTGTHVLNYALRKVLADS-DQKGSLVAPDRMRF 637
Cdd:PLN02900 553 --VEVSDVQKAGGFVLHIGTvTEGSVSVGDAVTCKVDYDRRRRIAPNHTATHLLNSALKEVLGDHvDQKGSLVAFEKLRF 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 638 DFTNKAGMTVQQVKKAEEYAQQLIDTKGQVYAKNSPLGEAKKVKGLRAMFDETYPDPVRVVAVGTPVeqllqnpdaeegq 717
Cdd:PLN02900 631 DFSHGKPMTPEELREVESLVNEWIGDALPVEAKEMPLADAKRINGLRAVFGEKYPDPVRVVSVGGVY------------- 697
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 718 ntTVEFCGGTHLQNVSHIGRIVIASEEAIAKGIRRIVALTGPEAERAIARADRLTARLEEeskhadkkdellANKDKFKA 797
Cdd:PLN02900 698 --SMELCGGTHVSNTAEAEAFKLLSEEGIAKGIRRITAVTGGAAVEAINAADSLERELDS------------ALKVEGSD 763
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 798 LQKKIQEIVDEANGAQLPYWRKDSIREKAKAIQKTLDGYTKAQQAAVAEKVLGEAKELA--AVAEQPTVLVHVFAANANS 875
Cdd:PLN02900 764 LEKKVASLKSRVDAAVIPAAKKEEIRARVSALQKELRAAQKEAAALRAKLAVAKATELAskALSAGKSVLVARLDVGVDA 843
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 876 KAIDNALKLLKDTK---AVMAFSVNEDSGKVLCLAKVDKSLVSNGLKANEWVNEVCTVLGGKGGGKDANAQLTGENVDKL 952
Cdd:PLN02900 844 AALKEAAEKVIAKLgdpAAVVLSSDEEKGKVSLVAAVPPGVVKKGLKAGKWLGAIAKLCGGGGGGKPGFAQGQGRDAEKL 923
|
970
....*....|...
gi 17506981 953 DAAVELAQKFALA 965
Cdd:PLN02900 924 DAALEKARAFAVA 936
|
|
| AlaS |
COG0013 |
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA ... |
4-967 |
0e+00 |
|
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439784 [Multi-domain] Cd Length: 880 Bit Score: 1001.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 4 LTASEVRSTFINFFrEKKEHTYVHSSSVIPHDDPTLLFANAGMNQFKPLFLGIADPNSdlaklKRAVNTQKCIRAGGKHN 83
Cdd:COG0013 2 MTSAEIRQKFLDFF-ESKGHTIVPSSSLVPKNDPTLLFTNAGMVQFKPYFLGQEKPPY-----PRATTSQKCVRTGGKHN 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 84 DLDDVGKDVYHHTYFEMLGNWSFGDYFKKEIITWAWELLTTVYGIPAERLYVSVFGGDEangvpadsEARDIWRS-VGVP 162
Cdd:COG0013 76 DLENVGYTARHHTFFEMLGNFSFGDYFKEEAIAWAWELLTEVLGLPKERLWVTVYEDDD--------EAYDIWKKeIGVP 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 163 DERILNFGMKDNFWEMGDVGPCGPCSEIHYDR---IGNrDASHLVNADDPMVVEIWNLVFIQFNREEGGVLKPLPAKHID 239
Cdd:COG0013 148 EERIIRLGKKDNFWEMGDTGPCGPCSEIFYDRgpeYGG-GPPGSPGEDGDRYIEIWNLVFMQFNRDEDGTLTPLPKKNID 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 240 CGLGLERLIAVMQDKTSNYDTDIFQPIFEAIHKGSGVRaYtgfiGDEDKDgvDMAYRVVADHVRTLTIALSDGGRPDNSG 319
Cdd:COG0013 227 TGMGLERIAAVLQGVHSNYETDLFRPLIEAAAELTGVK-Y----GADEED--DVSLRVIADHIRAVAFLIADGVLPSNEG 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 320 RGYVLRRILRRGVRYAsEKLNAQPGFFASLVPVVISILGETFPELSRDPVTVMDIINDEEKQFLKTLSRGRVLFQRAVQS 399
Cdd:COG0013 300 RGYVLRRILRRAVRHG-RLLGIKEPFLYKLVPVVVEEMGDAYPELKEKQELIEKVLKAEEERFLRTLERGLKLLDEAIAK 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 400 LPE-GTMTFPGDVSWRLYDTYGFPADLTQLMAEEKGLSVDNTAFEEARRKAIETSSAGtGKFRDTLDLDVhALAELQQKG 478
Cdd:COG0013 379 LKAaGGKVLSGEDAFKLYDTYGFPLDLTEEIARERGLTVDEEGFEAAMEEQRERARAA-AKFSGDAAVDG-VWRELLEEG 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 479 VPTtddspkyayTFTGegsdavYKFEPCVGKILAIRRDGKFVDQLAAGEEGAILLDRTNFYAEQGGQIYDVGVLTkvnDE 558
Cdd:COG0013 457 GPT---------EFVG------YDTLEAEAKVLALVKDGELVDSAKAGEEVEVVLDRTPFYAESGGQVGDTGTIE---GD 518
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 559 SNEFNVSNCQ-VRGGYIVLVGS-AEGSFSVGDQVNERFDEDRKQLIMKNHTGTHVLNYALRKVLADS-DQKGSLVAPDRM 635
Cdd:COG0013 519 GGVFEVTDTQkPPGGLIVHIGKvEEGELKVGDTVTAQVDAERRRAIARNHSATHLLHAALREVLGEHvTQAGSLVAPDRL 598
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 636 RFDFTNKAGMTVQQVKKAEEYAQQLIDTKGQVYAKNSPLGEAKKvKGLRAMFDETYPDPVRVVAVGtpveqllqnpdaee 715
Cdd:COG0013 599 RFDFSHFEALTPEELAEIEDLVNEKIRENLPVETREMPLDEAKA-LGAMALFGEKYGDEVRVVSIG-------------- 663
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 716 gqNTTVEFCGGTHLQNVSHIGRIVIASEEAIAKGIRRIVALTGPEAERAIARADRLTARLEeeskhadkkdELLanKDKF 795
Cdd:COG0013 664 --DFSRELCGGTHVSRTGDIGLFKIVSESSVAAGVRRIEAVTGEAALEYLREQEALLKELA----------ELL--KAPP 729
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 796 KALQKKIQEIVDEangaqlpywrkdsirekAKAIQKTLDGYTKAQQAAVAEKVLGEAKELAAVaeqpTVLVHVFaANANS 875
Cdd:COG0013 730 EELPERVEALLEE-----------------LKELEKELEQLKAKLASAAADDLLAQAEEIGGV----KVLAARV-EGVDA 787
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 876 KAIDNALKLLKD---TKAVMAFSVNEdsGKVLCLAKVDKSLVSNGLKANEWVNEVCTVLGGKGGGKDANAQLTGENVDKL 952
Cdd:COG0013 788 KDLRDLADDLKDklgSGVVVLASVAD--GKVSLVAGVTKDLVKKGLKAGDLVKEVAKIVGGGGGGRPDMAQAGGKDPSKL 865
|
970
....*....|....*
gi 17506981 953 DAAVELAQKFALAAI 967
Cdd:COG0013 866 DEALAAVKEWLAEKL 880
|
|
| tRNA-synt_2c |
pfam01411 |
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be ... |
8-598 |
0e+00 |
|
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only alanyl-tRNA synthetases.
Pssm-ID: 279719 [Multi-domain] Cd Length: 548 Bit Score: 834.23 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 8 EVRSTFINFFrEKKEHTYVHSSSVIPHDDPTLLFANAGMNQFKPLFLGIADPnsdlAKLKRAVNTQKCIRAGgkhnDLDD 87
Cdd:pfam01411 1 EIRQTFLDFF-EKKGHTRVPSSPVVPRNDPTLLFTNAGMNQFKPIFLGGVAK----PPYNRATNSQKCIRAG----DLEN 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 88 VGKDVYHHTYFEMLGNWSFGDYFKKEIITWAWELLTTVYGIPAERLYVSVFGGDEangvpadsEARDIWRS-VGVPDERI 166
Cdd:pfam01411 72 VGRTGRHHTFFEMLGNFSFGDYFKEEAIEYAWELLTKELGLPPERLYVTVFEWDD--------EAGPIWEKiVGGPEERI 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 167 LNFGMKDNFWEMGDVGPCGPCSEIHYDR---IGNRDASHLVNADDPMVVEIWNLVFIQFNREEGGVLKPLPAKHIDCGLG 243
Cdd:pfam01411 144 LRFGDKDNFWEMGDTGPCGPCSEIDYDRgeeIGGWDSGGTPTADDDRFLEIWNLVFMQFNRENDGTLKPLPKKSIDTGMG 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 244 LERLIAVMQDKTSNYDTDIFQPIFEAIHKGSGVRAYTgfigdedKDGVDMAYRVVADHVRTLTIALSDGGRPDNSGRGYV 323
Cdd:pfam01411 224 LERLVAVLQDVRSNYDTDVFIPVIELIEEISGARYYT-------VDETDEAYRVIADHTRALTFALADGVVPSNEGRGYV 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 324 LRRILRRGVRYAsEKLNAQPGFFASLVPVVISILGETFPELSRDPVTVMDIINDEEKQFLKTLSRGRVLFQRAVQSLPEG 403
Cdd:pfam01411 297 LRRILRRAVRHA-KKLGLKEPFLYDLVPTVVEVLGDAYPELKEDEDFIQEILELEEERFAKTLERGLRLLERLIAKLKKG 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 404 TMTFPGDVSWRLYDTYGFPADLTQLMAEEKGLSVDNTAFEEARRKAIETSSAGTGKFRdtLDLDVHALAELqqkgvPTTD 483
Cdd:pfam01411 376 KKTLPGEDAFKLYDTYGFPVDLTKEIAEERGLKVDMPGFEYAMVEQRERSKQAVKEKG--EKLDVSALKEL-----PATT 448
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 484 DSPKYAYTftgegsdavykfePCVGKILAIRRDGKFVDQLAAGEEGAILLDRTNFYAEQGGQIYDVGVLtkvNDESNEFN 563
Cdd:pfam01411 449 EFLGYDDL-------------ESEAKILALPKDGEFVAEVLAGQEGGVILDRTPFYAESGGQIGDTGYI---IGDGGEFR 512
|
570 580 590
....*....|....*....|....*....|....*.
gi 17506981 564 VSNCQVRGGYIVLVGSAE-GSFSVGDQVNERFDEDR 598
Cdd:pfam01411 513 VTDVQKYGGVVVHKGKLEsGKLKVGDKVIAVIDEDR 548
|
|
| alaS |
TIGR00344 |
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the ... |
8-943 |
0e+00 |
|
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the reaction (tRNAala + L-alanine + ATP = L-alanyl-tRNAala + pyrophosphate + AMP). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273026 [Multi-domain] Cd Length: 845 Bit Score: 783.88 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 8 EVRSTFINFFrEKKEHTYVHSSSVIPHDDPTLLFANAGMNQFKPLFLGIADPNSdlaklKRAVNTQKCIRAggkhNDLDD 87
Cdd:TIGR00344 1 EIRQTFLDFF-KEKGHQVIPSAPLVPRNDPTLLLTNAGMAQFKPIFTGIVKPPS-----NRLTNAQPCIRL----NDLEN 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 88 VGKDVYHHTYFEMLGNWSFGDYFKKEIITWAWELLTTVYGIPAERLYVSVFGGDEangvpadsEARDIWRSVGVPDERIL 167
Cdd:TIGR00344 71 VGRTARHHTLFEMLGNFSFGDYFKEEAIAFAWELLTEVLGLDKERLYVTVYEDDE--------EAYKIWEKIGIPADRII 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 168 NFGMKDNFWEMGDvGPCGPCSEIHYDRIGNRDASHLVnaDDPMVVEIWNLVFIQFNREEGGVLKPLPAKHIDCGLGLERL 247
Cdd:TIGR00344 143 KCDAKDNFWDMGD-GPCGPCTEIYYDFVGGKPGEPLE--ENDRYLEVWNLVFMQFNRDPDGNYTPLPKKNIDTGMGLERF 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 248 IAVMQDKTSNYDTDIFQPIFEAIHKGSGVRAYTGFIGDEDKDGVD--MAYRVVADHVRTLTIALSDGGRPDNSGRGYVLR 325
Cdd:TIGR00344 220 VAVLQGVPTNYDTDIFLPLIEKIEEITGVKYDSNNAGIMDEKRVEdlRSLRVIADHTRAIAFMLADGVVPSNEGRGYVLR 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 326 RILRRGVRYAsEKLNAQPGFFASLVPVVISILGETFPELSRDPVTVMDIINDEEKQFLKTLSRGRVLFQRAVQSLpeGTM 405
Cdd:TIGR00344 300 RLIRRALRHG-KKLGLKEAFLYKLVPTLIEVLGDYYPELKEKQEFVEQILELEEERFAKTLERGLRLFEKLLKKT--GKK 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 406 TFPGDVSWRLYDTYGFPADLTQLMAEEKGLSVDNTAFEEARRKAIETSSAGTGkfrdtLDLDVHALAElqqkgVPTTDDS 485
Cdd:TIGR00344 377 ELDGEDAFKLYDTYGFPVELTKEIAEERGLTVDMPGFEALMAEQRERSKQNSQ-----FQEQEIALVN-----VYPATEF 446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 486 PKYAYTftgegsdavyKFEpcvGKILAIRRDGKFVDQLAAGEEGAILLDRTNFYAEQGGQIYDVGVLTKvndESNEFNVS 565
Cdd:TIGR00344 447 LGYDDL----------EFE---AKVIGLFDDGYLVEQALAGQSVYVILDQTPFYAESGGQIGDTGYLIA---NDGKFRVV 510
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 566 NCQVRGGYIVLVGSAE-GSFSVGDQVNERFDEDRKQLIMKNHTGTHVLNYALRKVLADS-DQKGSLVAPDRMRFDFTNKA 643
Cdd:TIGR00344 511 DVQKPNGVVFHFGEVEgGSLKVGDKVIAVIDEKRRFRIMRNHSATHLLHAALQKVLGNHvWQAGSLVSFKKLRFDFSHFR 590
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 644 GMTVQQVKKAEEYAQQLIDTKGQVYAKNSPLGEAKKvKGLRAMFDETYP--DPVRVVAVGtpveqllqnpdaeegqNTTV 721
Cdd:TIGR00344 591 ALTREELEEIEDLANEQILANIPIKVIFMDLDEAKR-KGAFALFGEKYVpgEKVRVVSVG----------------DFSV 653
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 722 EFCGGTHLQNVSHIGRIVIASEEAIAKGIRRIVALTGPEA-ERAIARADRLT---ARLEEESKHADKKDELLanKDKFKA 797
Cdd:TIGR00344 654 ELCGGTHVRNTGEIGLFKIVKESGIAAGVRRIEAVTGEAAiEYLNEQEDKLKelaDILKVTPNELPKKVERF--FEEWKA 731
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 798 LQKKIQEIvDEANGAQlpywRKDSIREKAkaiqKTLDGYTkaqqaAVAEKVLG-EAKELAAVAEQptvlvhvFAANANSK 876
Cdd:TIGR00344 732 LQKELESL-KLKIADQ----KIDELKDKA----ETINGVK-----VLVEVVDAkDMKSLKTMADR-------LKSKLGSA 790
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 17506981 877 AIdnalkllkdtkaVMAFSVNedsGKVLCLAKVDKSLVSNGLKANEWVNEVCTVLGGKGGGKDANAQ 943
Cdd:TIGR00344 791 IY------------VLASFAE---GKVKLVCGVSNDVLTKKIKAGELINQIAQVLGGKGGGRPDFAQ 842
|
|
| AlaRS_core |
cd00673 |
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is ... |
6-254 |
2.68e-140 |
|
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. Class II assignment is based upon its predicted structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238360 [Multi-domain] Cd Length: 232 Bit Score: 418.30 E-value: 2.68e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 6 ASEVRSTFINFFrEKKEHTYVHSSSVIPHDDPTLLFANAGMNQFKPLFLGIADPNSdlaklKRAVNTQKCIRAGGKHNdl 85
Cdd:cd00673 1 ASEIRETFLSFF-EKKGHTRVPSSPVVPRDDPTLLFTNAGMNQFKPIFLGEVPPPA-----NRLVNSQKCIRAGDIDN-- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 86 ddVGKDVYHHTYFEMLGNWSFGDYFKKEIITWAWELLTTVYGIPAERLYVSVFGGDeangvpaDSEARDIWRSVGVPDER 165
Cdd:cd00673 73 --VGKTGRHHTFFEMLGNFSFGDYFKEEAIAFAWELLTEVLGLPKDRLYVSVFEGD-------DEEEAIWWWKIGLPGIR 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 166 ILNFGMKDNFWEMGDVGPCGPCSEIHYDRIGNRDASHLVNADDPMVVEIWNLVFIQFNREEGGVLKPLPAKHIDCGLGLE 245
Cdd:cd00673 144 IERIGFKDNFWEMGGNGPCGPCSEIFYDRGEERDAASLPNEDDDRYLEIWNLVFMQYNRDADGTYRPLPKKIVDTGMGLE 223
|
....*....
gi 17506981 246 RLIAVMQDK 254
Cdd:cd00673 224 RLVWVLQGV 232
|
|
| tRNA_SAD |
smart00863 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of ... |
695-753 |
5.70e-10 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this SAD domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 197931 [Multi-domain] Cd Length: 43 Bit Score: 55.47 E-value: 5.70e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 17506981 695 VRVVAVGtpveqllqnpdaeegqNTTVEFCGGTHLQNVSHIGRIVIASEEAIAKGIRRI 753
Cdd:smart00863 1 VRVVSIG----------------DFSVELCGGTHVPNTGEIGAFKILSVSGAYWGLQRI 43
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02900 |
PLN02900 |
alanyl-tRNA synthetase |
5-965 |
0e+00 |
|
alanyl-tRNA synthetase
Pssm-ID: 215487 [Multi-domain] Cd Length: 936 Bit Score: 1181.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 5 TASEVRSTFINFFrEKKEHTYVHSSSVIPHDDPTLLFANAGMNQFKPLFLGIADPNSDLAKLKRAVNTQKCIRAGGKHND 84
Cdd:PLN02900 12 PGDRIRRTFLSFF-ESKGHTFLPSSPLVPVDDPTLLFTNAGMNQFKPIFLGTADPNTPLRKLPRATNTQKCIRAGGKHND 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 85 LDDVGKDVYHHTYFEMLGNWSFGDYFKKEIITWAWELLTTVYGIPAERLYVSVFGGDEAngVPADSEARDIWRSVgVPDE 164
Cdd:PLN02900 91 LDDVGKDTYHHTFFEMLGNWSFGDYFKKEAIGWAWELLTKVYGLPADRLYATYFGGDEK--QAPDDEARAIWLDY-LPEE 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 165 RILNFGMKDNFWEMGDVGPCGPCSEIHYDRIGNRDASHLVNADDPMVVEIWNLVFIQFNREEGGVLKPLPAKHIDCGLGL 244
Cdd:PLN02900 168 RVLPFGCKDNFWEMGDTGPCGPCSEIHYDRIGERDAADLVNNDDPRFIEIWNLVFIQFNREADGSLKPLPAKHVDTGMGL 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 245 ERLIAVMQDKTSNYDTDIFQPIFEAIHKGSGVRAYTGFIGDEDKDGVDMAYRVVADHVRTLTIALSDGGRPDNSGRGYVL 324
Cdd:PLN02900 248 ERLASILQNKPSNYDTDLFMPIFDAIQEATGARPYAGKVGAEDDDRVDMAYRVVADHIRTLSFAIADGVVPSNEGRGYVL 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 325 RRILRRGVRYASEKLNAQPGFFASLVPVVISILGETFPELSRDPVTVMDIINDEEKQFLKTLSRGRVLFQRAVQS-LPEG 403
Cdd:PLN02900 328 RRLLRRAVRYGRLLLGAEEGFFPALVEVVVELSGDVFPEVKKNEKRITEIIAEEELSFGKTLEKGIEKFKKALAAaKANG 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 404 TMTFPGDVSWRLYDTYGFPADLTQLMAEEKGLSVD----NTAFEEARRKAIETSSAGTGKfrdTLDLDVHALAELQQKGV 479
Cdd:PLN02900 408 GPVLSGKDAFLLYDTYGFPVDLTELMAEERGVTVDmegfEAAMEEARERSRAAHLKAGGG---AIELAAEATSWLQKQGV 484
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 480 PTTDDSPKYAYtftgegsdavykFEPCVGKILAIRRDGKFVDQLAAGEEGAILLDRTNFYAEQGGQIYDVGVLTKVNDES 559
Cdd:PLN02900 485 AATDDFLKYDW------------LSDHEAVVKAILTGGGFVESVSEGDEVGIVLDKTSFYAESGGQIGDTGVLEGSGGAV 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 560 neFNVSNCQVRGGYIVLVGS-AEGSFSVGDQVNERFDEDRKQLIMKNHTGTHVLNYALRKVLADS-DQKGSLVAPDRMRF 637
Cdd:PLN02900 553 --VEVSDVQKAGGFVLHIGTvTEGSVSVGDAVTCKVDYDRRRRIAPNHTATHLLNSALKEVLGDHvDQKGSLVAFEKLRF 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 638 DFTNKAGMTVQQVKKAEEYAQQLIDTKGQVYAKNSPLGEAKKVKGLRAMFDETYPDPVRVVAVGTPVeqllqnpdaeegq 717
Cdd:PLN02900 631 DFSHGKPMTPEELREVESLVNEWIGDALPVEAKEMPLADAKRINGLRAVFGEKYPDPVRVVSVGGVY------------- 697
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 718 ntTVEFCGGTHLQNVSHIGRIVIASEEAIAKGIRRIVALTGPEAERAIARADRLTARLEEeskhadkkdellANKDKFKA 797
Cdd:PLN02900 698 --SMELCGGTHVSNTAEAEAFKLLSEEGIAKGIRRITAVTGGAAVEAINAADSLERELDS------------ALKVEGSD 763
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 798 LQKKIQEIVDEANGAQLPYWRKDSIREKAKAIQKTLDGYTKAQQAAVAEKVLGEAKELA--AVAEQPTVLVHVFAANANS 875
Cdd:PLN02900 764 LEKKVASLKSRVDAAVIPAAKKEEIRARVSALQKELRAAQKEAAALRAKLAVAKATELAskALSAGKSVLVARLDVGVDA 843
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 876 KAIDNALKLLKDTK---AVMAFSVNEDSGKVLCLAKVDKSLVSNGLKANEWVNEVCTVLGGKGGGKDANAQLTGENVDKL 952
Cdd:PLN02900 844 AALKEAAEKVIAKLgdpAAVVLSSDEEKGKVSLVAAVPPGVVKKGLKAGKWLGAIAKLCGGGGGGKPGFAQGQGRDAEKL 923
|
970
....*....|...
gi 17506981 953 DAAVELAQKFALA 965
Cdd:PLN02900 924 DAALEKARAFAVA 936
|
|
| AlaS |
COG0013 |
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA ... |
4-967 |
0e+00 |
|
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439784 [Multi-domain] Cd Length: 880 Bit Score: 1001.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 4 LTASEVRSTFINFFrEKKEHTYVHSSSVIPHDDPTLLFANAGMNQFKPLFLGIADPNSdlaklKRAVNTQKCIRAGGKHN 83
Cdd:COG0013 2 MTSAEIRQKFLDFF-ESKGHTIVPSSSLVPKNDPTLLFTNAGMVQFKPYFLGQEKPPY-----PRATTSQKCVRTGGKHN 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 84 DLDDVGKDVYHHTYFEMLGNWSFGDYFKKEIITWAWELLTTVYGIPAERLYVSVFGGDEangvpadsEARDIWRS-VGVP 162
Cdd:COG0013 76 DLENVGYTARHHTFFEMLGNFSFGDYFKEEAIAWAWELLTEVLGLPKERLWVTVYEDDD--------EAYDIWKKeIGVP 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 163 DERILNFGMKDNFWEMGDVGPCGPCSEIHYDR---IGNrDASHLVNADDPMVVEIWNLVFIQFNREEGGVLKPLPAKHID 239
Cdd:COG0013 148 EERIIRLGKKDNFWEMGDTGPCGPCSEIFYDRgpeYGG-GPPGSPGEDGDRYIEIWNLVFMQFNRDEDGTLTPLPKKNID 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 240 CGLGLERLIAVMQDKTSNYDTDIFQPIFEAIHKGSGVRaYtgfiGDEDKDgvDMAYRVVADHVRTLTIALSDGGRPDNSG 319
Cdd:COG0013 227 TGMGLERIAAVLQGVHSNYETDLFRPLIEAAAELTGVK-Y----GADEED--DVSLRVIADHIRAVAFLIADGVLPSNEG 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 320 RGYVLRRILRRGVRYAsEKLNAQPGFFASLVPVVISILGETFPELSRDPVTVMDIINDEEKQFLKTLSRGRVLFQRAVQS 399
Cdd:COG0013 300 RGYVLRRILRRAVRHG-RLLGIKEPFLYKLVPVVVEEMGDAYPELKEKQELIEKVLKAEEERFLRTLERGLKLLDEAIAK 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 400 LPE-GTMTFPGDVSWRLYDTYGFPADLTQLMAEEKGLSVDNTAFEEARRKAIETSSAGtGKFRDTLDLDVhALAELQQKG 478
Cdd:COG0013 379 LKAaGGKVLSGEDAFKLYDTYGFPLDLTEEIARERGLTVDEEGFEAAMEEQRERARAA-AKFSGDAAVDG-VWRELLEEG 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 479 VPTtddspkyayTFTGegsdavYKFEPCVGKILAIRRDGKFVDQLAAGEEGAILLDRTNFYAEQGGQIYDVGVLTkvnDE 558
Cdd:COG0013 457 GPT---------EFVG------YDTLEAEAKVLALVKDGELVDSAKAGEEVEVVLDRTPFYAESGGQVGDTGTIE---GD 518
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 559 SNEFNVSNCQ-VRGGYIVLVGS-AEGSFSVGDQVNERFDEDRKQLIMKNHTGTHVLNYALRKVLADS-DQKGSLVAPDRM 635
Cdd:COG0013 519 GGVFEVTDTQkPPGGLIVHIGKvEEGELKVGDTVTAQVDAERRRAIARNHSATHLLHAALREVLGEHvTQAGSLVAPDRL 598
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 636 RFDFTNKAGMTVQQVKKAEEYAQQLIDTKGQVYAKNSPLGEAKKvKGLRAMFDETYPDPVRVVAVGtpveqllqnpdaee 715
Cdd:COG0013 599 RFDFSHFEALTPEELAEIEDLVNEKIRENLPVETREMPLDEAKA-LGAMALFGEKYGDEVRVVSIG-------------- 663
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 716 gqNTTVEFCGGTHLQNVSHIGRIVIASEEAIAKGIRRIVALTGPEAERAIARADRLTARLEeeskhadkkdELLanKDKF 795
Cdd:COG0013 664 --DFSRELCGGTHVSRTGDIGLFKIVSESSVAAGVRRIEAVTGEAALEYLREQEALLKELA----------ELL--KAPP 729
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 796 KALQKKIQEIVDEangaqlpywrkdsirekAKAIQKTLDGYTKAQQAAVAEKVLGEAKELAAVaeqpTVLVHVFaANANS 875
Cdd:COG0013 730 EELPERVEALLEE-----------------LKELEKELEQLKAKLASAAADDLLAQAEEIGGV----KVLAARV-EGVDA 787
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 876 KAIDNALKLLKD---TKAVMAFSVNEdsGKVLCLAKVDKSLVSNGLKANEWVNEVCTVLGGKGGGKDANAQLTGENVDKL 952
Cdd:COG0013 788 KDLRDLADDLKDklgSGVVVLASVAD--GKVSLVAGVTKDLVKKGLKAGDLVKEVAKIVGGGGGGRPDMAQAGGKDPSKL 865
|
970
....*....|....*
gi 17506981 953 DAAVELAQKFALAAI 967
Cdd:COG0013 866 DEALAAVKEWLAEKL 880
|
|
| tRNA-synt_2c |
pfam01411 |
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be ... |
8-598 |
0e+00 |
|
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only alanyl-tRNA synthetases.
Pssm-ID: 279719 [Multi-domain] Cd Length: 548 Bit Score: 834.23 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 8 EVRSTFINFFrEKKEHTYVHSSSVIPHDDPTLLFANAGMNQFKPLFLGIADPnsdlAKLKRAVNTQKCIRAGgkhnDLDD 87
Cdd:pfam01411 1 EIRQTFLDFF-EKKGHTRVPSSPVVPRNDPTLLFTNAGMNQFKPIFLGGVAK----PPYNRATNSQKCIRAG----DLEN 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 88 VGKDVYHHTYFEMLGNWSFGDYFKKEIITWAWELLTTVYGIPAERLYVSVFGGDEangvpadsEARDIWRS-VGVPDERI 166
Cdd:pfam01411 72 VGRTGRHHTFFEMLGNFSFGDYFKEEAIEYAWELLTKELGLPPERLYVTVFEWDD--------EAGPIWEKiVGGPEERI 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 167 LNFGMKDNFWEMGDVGPCGPCSEIHYDR---IGNRDASHLVNADDPMVVEIWNLVFIQFNREEGGVLKPLPAKHIDCGLG 243
Cdd:pfam01411 144 LRFGDKDNFWEMGDTGPCGPCSEIDYDRgeeIGGWDSGGTPTADDDRFLEIWNLVFMQFNRENDGTLKPLPKKSIDTGMG 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 244 LERLIAVMQDKTSNYDTDIFQPIFEAIHKGSGVRAYTgfigdedKDGVDMAYRVVADHVRTLTIALSDGGRPDNSGRGYV 323
Cdd:pfam01411 224 LERLVAVLQDVRSNYDTDVFIPVIELIEEISGARYYT-------VDETDEAYRVIADHTRALTFALADGVVPSNEGRGYV 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 324 LRRILRRGVRYAsEKLNAQPGFFASLVPVVISILGETFPELSRDPVTVMDIINDEEKQFLKTLSRGRVLFQRAVQSLPEG 403
Cdd:pfam01411 297 LRRILRRAVRHA-KKLGLKEPFLYDLVPTVVEVLGDAYPELKEDEDFIQEILELEEERFAKTLERGLRLLERLIAKLKKG 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 404 TMTFPGDVSWRLYDTYGFPADLTQLMAEEKGLSVDNTAFEEARRKAIETSSAGTGKFRdtLDLDVHALAELqqkgvPTTD 483
Cdd:pfam01411 376 KKTLPGEDAFKLYDTYGFPVDLTKEIAEERGLKVDMPGFEYAMVEQRERSKQAVKEKG--EKLDVSALKEL-----PATT 448
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 484 DSPKYAYTftgegsdavykfePCVGKILAIRRDGKFVDQLAAGEEGAILLDRTNFYAEQGGQIYDVGVLtkvNDESNEFN 563
Cdd:pfam01411 449 EFLGYDDL-------------ESEAKILALPKDGEFVAEVLAGQEGGVILDRTPFYAESGGQIGDTGYI---IGDGGEFR 512
|
570 580 590
....*....|....*....|....*....|....*.
gi 17506981 564 VSNCQVRGGYIVLVGSAE-GSFSVGDQVNERFDEDR 598
Cdd:pfam01411 513 VTDVQKYGGVVVHKGKLEsGKLKVGDKVIAVIDEDR 548
|
|
| alaS |
TIGR00344 |
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the ... |
8-943 |
0e+00 |
|
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the reaction (tRNAala + L-alanine + ATP = L-alanyl-tRNAala + pyrophosphate + AMP). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273026 [Multi-domain] Cd Length: 845 Bit Score: 783.88 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 8 EVRSTFINFFrEKKEHTYVHSSSVIPHDDPTLLFANAGMNQFKPLFLGIADPNSdlaklKRAVNTQKCIRAggkhNDLDD 87
Cdd:TIGR00344 1 EIRQTFLDFF-KEKGHQVIPSAPLVPRNDPTLLLTNAGMAQFKPIFTGIVKPPS-----NRLTNAQPCIRL----NDLEN 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 88 VGKDVYHHTYFEMLGNWSFGDYFKKEIITWAWELLTTVYGIPAERLYVSVFGGDEangvpadsEARDIWRSVGVPDERIL 167
Cdd:TIGR00344 71 VGRTARHHTLFEMLGNFSFGDYFKEEAIAFAWELLTEVLGLDKERLYVTVYEDDE--------EAYKIWEKIGIPADRII 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 168 NFGMKDNFWEMGDvGPCGPCSEIHYDRIGNRDASHLVnaDDPMVVEIWNLVFIQFNREEGGVLKPLPAKHIDCGLGLERL 247
Cdd:TIGR00344 143 KCDAKDNFWDMGD-GPCGPCTEIYYDFVGGKPGEPLE--ENDRYLEVWNLVFMQFNRDPDGNYTPLPKKNIDTGMGLERF 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 248 IAVMQDKTSNYDTDIFQPIFEAIHKGSGVRAYTGFIGDEDKDGVD--MAYRVVADHVRTLTIALSDGGRPDNSGRGYVLR 325
Cdd:TIGR00344 220 VAVLQGVPTNYDTDIFLPLIEKIEEITGVKYDSNNAGIMDEKRVEdlRSLRVIADHTRAIAFMLADGVVPSNEGRGYVLR 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 326 RILRRGVRYAsEKLNAQPGFFASLVPVVISILGETFPELSRDPVTVMDIINDEEKQFLKTLSRGRVLFQRAVQSLpeGTM 405
Cdd:TIGR00344 300 RLIRRALRHG-KKLGLKEAFLYKLVPTLIEVLGDYYPELKEKQEFVEQILELEEERFAKTLERGLRLFEKLLKKT--GKK 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 406 TFPGDVSWRLYDTYGFPADLTQLMAEEKGLSVDNTAFEEARRKAIETSSAGTGkfrdtLDLDVHALAElqqkgVPTTDDS 485
Cdd:TIGR00344 377 ELDGEDAFKLYDTYGFPVELTKEIAEERGLTVDMPGFEALMAEQRERSKQNSQ-----FQEQEIALVN-----VYPATEF 446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 486 PKYAYTftgegsdavyKFEpcvGKILAIRRDGKFVDQLAAGEEGAILLDRTNFYAEQGGQIYDVGVLTKvndESNEFNVS 565
Cdd:TIGR00344 447 LGYDDL----------EFE---AKVIGLFDDGYLVEQALAGQSVYVILDQTPFYAESGGQIGDTGYLIA---NDGKFRVV 510
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 566 NCQVRGGYIVLVGSAE-GSFSVGDQVNERFDEDRKQLIMKNHTGTHVLNYALRKVLADS-DQKGSLVAPDRMRFDFTNKA 643
Cdd:TIGR00344 511 DVQKPNGVVFHFGEVEgGSLKVGDKVIAVIDEKRRFRIMRNHSATHLLHAALQKVLGNHvWQAGSLVSFKKLRFDFSHFR 590
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 644 GMTVQQVKKAEEYAQQLIDTKGQVYAKNSPLGEAKKvKGLRAMFDETYP--DPVRVVAVGtpveqllqnpdaeegqNTTV 721
Cdd:TIGR00344 591 ALTREELEEIEDLANEQILANIPIKVIFMDLDEAKR-KGAFALFGEKYVpgEKVRVVSVG----------------DFSV 653
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 722 EFCGGTHLQNVSHIGRIVIASEEAIAKGIRRIVALTGPEA-ERAIARADRLT---ARLEEESKHADKKDELLanKDKFKA 797
Cdd:TIGR00344 654 ELCGGTHVRNTGEIGLFKIVKESGIAAGVRRIEAVTGEAAiEYLNEQEDKLKelaDILKVTPNELPKKVERF--FEEWKA 731
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 798 LQKKIQEIvDEANGAQlpywRKDSIREKAkaiqKTLDGYTkaqqaAVAEKVLG-EAKELAAVAEQptvlvhvFAANANSK 876
Cdd:TIGR00344 732 LQKELESL-KLKIADQ----KIDELKDKA----ETINGVK-----VLVEVVDAkDMKSLKTMADR-------LKSKLGSA 790
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 17506981 877 AIdnalkllkdtkaVMAFSVNedsGKVLCLAKVDKSLVSNGLKANEWVNEVCTVLGGKGGGKDANAQ 943
Cdd:TIGR00344 791 IY------------VLASFAE---GKVKLVCGVSNDVLTKKIKAGELINQIAQVLGGKGGGRPDFAQ 842
|
|
| PRK01584 |
PRK01584 |
alanyl-tRNA synthetase; Provisional |
4-756 |
1.14e-143 |
|
alanyl-tRNA synthetase; Provisional
Pssm-ID: 234962 [Multi-domain] Cd Length: 594 Bit Score: 440.75 E-value: 1.14e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 4 LTASEVRSTFINFFREKKeHTYVHSSSVIPHDDPTLLFANAGMNQFKPLFLGIADPNSDlaklkRAVNTQKCIRAGgkhn 83
Cdd:PRK01584 1 MTLDELRKKYIDFFKSKG-HVEIAGKSLIPENDPTVLFTTAGMHPLVPYLLGEPHPSGT-----RLVDVQKCLRTG---- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 84 DLDDVGkDVYHHTYFEMLGNWSFGDYFKKEIITWAWELLTT--VYGIPAERLYVSVFGGDEAngVPADSEARDIWRSVGV 161
Cdd:PRK01584 71 DIDEVG-DLSHLTFFEMLGNWSLGAYFKEESIKYSFEFLTSpdYLNIPKDKLYVTVFEGDEE--IPRDEETASVWESLGI 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 162 PDERILNFGMKDNFW-EMGDVGPCGPCSEIHYDrIGNRDAShlvNADDPMV-----VEIWNLVFIQFNREEGGVLKPLPA 235
Cdd:PRK01584 148 PKDRIFYLSREHNWWgPVGETGPCGPDTEIFVD-TGKPKCS---VNCRPTCscgkyFEIWNNVFMQYNKDEDGNYEELKR 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 236 KHIDCGLGLERLIAVMQDKTSNYDTDIFQPIFEAIHKGSGVRaytgfIGDEDKDgvDMAYRVVADHVRTLTIALSD--GG 313
Cdd:PRK01584 224 KCVDTGMGIERTIAFLQGKSSVYDTEAFTPIIKRIEKISGKI-----YGQNEED--DRSIRIIADHIRAACFILGDpfVV 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 314 RPDNSGRGYVLRRILRRGVRYAsEKLNAQPGFFASLVPVVISILGETFPELSRDPVTVMDIINDEEKQFLKTLSRGRVLF 393
Cdd:PRK01584 297 LPSNVGQGYVLRRLIRRSIRHA-KKLGIESHFLADLVDSVEEIYGSFYPELTEKKDFIKEELNKEEEKFFKTLRKGEQEF 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 394 QRAVQSLPEgTMTFPGDVSWRLYDTYGFPADLTQLMAEEKGLSVDNTAFEEARRKAIETSSAgtgkfrdtldldvhalae 473
Cdd:PRK01584 376 IKLIPNLGS-SKIIPGDIAFKLYDTYGFPYEITEELASEYGFTVDREGFDEHFKKHQKVSKK------------------ 436
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 474 lqqkgvpttddspkyaytftgeGSDAVYKfepcvgkilairrdgkfvdqlaageegailldrtnfyaeqGGqiydvgvlt 553
Cdd:PRK01584 437 ----------------------GADKVFK----------------------------------------GG--------- 445
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 554 kVNDESNEfnvsncqvrggyivlvgsaegsfsvgdqvnerfdedrkqlIMKNHTGTHVLNYALRKVLADS-DQKGSLVAP 632
Cdd:PRK01584 446 -LADHSYE----------------------------------------TTKLHTATHLLHKALRLVLGDHvRQKGSNITA 484
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 633 DRMRFDFTNKAGMTVQQVKKAEEYAQQLIDTKGQVYAKNSPLGEAKKvKGLRAMFDETYPDPVRVVAVGTpveqllqnpd 712
Cdd:PRK01584 485 ERLRFDFSHPEKMTDDEIKKVEDIVNLQIKNDLSVKKEVMSLEEARE-KGAMALFGEKYEDIVKVYEIDG---------- 553
|
730 740 750 760
....*....|....*....|....*....|....*....|....
gi 17506981 713 aeegqnTTVEFCGGTHLQNVSHIGRIVIASEEAIAKGIRRIVAL 756
Cdd:PRK01584 554 ------FSKEVCGGPHVENTGELGTFKIQKEQSSSSGVRRIRAI 591
|
|
| AlaRS_core |
cd00673 |
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is ... |
6-254 |
2.68e-140 |
|
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. Class II assignment is based upon its predicted structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238360 [Multi-domain] Cd Length: 232 Bit Score: 418.30 E-value: 2.68e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 6 ASEVRSTFINFFrEKKEHTYVHSSSVIPHDDPTLLFANAGMNQFKPLFLGIADPNSdlaklKRAVNTQKCIRAGGKHNdl 85
Cdd:cd00673 1 ASEIRETFLSFF-EKKGHTRVPSSPVVPRDDPTLLFTNAGMNQFKPIFLGEVPPPA-----NRLVNSQKCIRAGDIDN-- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 86 ddVGKDVYHHTYFEMLGNWSFGDYFKKEIITWAWELLTTVYGIPAERLYVSVFGGDeangvpaDSEARDIWRSVGVPDER 165
Cdd:cd00673 73 --VGKTGRHHTFFEMLGNFSFGDYFKEEAIAFAWELLTEVLGLPKDRLYVSVFEGD-------DEEEAIWWWKIGLPGIR 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 166 ILNFGMKDNFWEMGDVGPCGPCSEIHYDRIGNRDASHLVNADDPMVVEIWNLVFIQFNREEGGVLKPLPAKHIDCGLGLE 245
Cdd:cd00673 144 IERIGFKDNFWEMGGNGPCGPCSEIFYDRGEERDAASLPNEDDDRYLEIWNLVFMQYNRDADGTYRPLPKKIVDTGMGLE 223
|
....*....
gi 17506981 246 RLIAVMQDK 254
Cdd:cd00673 224 RLVWVLQGV 232
|
|
| AlaX |
COG2872 |
Ser-tRNA(Ala) deacylase AlaX (editing enzyme) [Translation, ribosomal structure and biogenesis] ... |
523-754 |
2.74e-30 |
|
Ser-tRNA(Ala) deacylase AlaX (editing enzyme) [Translation, ribosomal structure and biogenesis];
Pssm-ID: 442119 [Multi-domain] Cd Length: 238 Bit Score: 119.91 E-value: 2.74e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 523 LAAGEEGAILLDRTNFYAEQGGQIYDVGVLTKvndESNEFNVSNCQVRGGYIVLVGSAEGSFSVGDQVNERFDEDRKQLI 602
Cdd:COG2872 20 TAVTEEGGVVLDRTAFYPTGGGQPGDTGTLVW---DGKEIRVVDVRKEDGEIVHVLEGAPLPEVGDEVTGEIDWERRYRH 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 603 MKNHTGTHVLNYALRKvLADSDQKGSLVAPDRMRFDFtNKAGMTVQQVKKAEEYAQQLIDTKGQVYAKNSPLGEAKKVKG 682
Cdd:COG2872 97 MRLHTALHLLSAVVYR-EYGAPVTGGQIGEDRARIDF-DLPEFDEEDLEEIEAEANELIAADLPVRIYWITREELEAIPG 174
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 17506981 683 L-RAMFDETYP--DPVRVVAVG----TPveqllqnpdaeegqnttvefCGGTHLQNVSHIGRIVIASEEAIAKGIRRIV 754
Cdd:COG2872 175 LvRTMSVLPPPgvGRVRIVEIGgvdlQP--------------------CGGTHVANTGEIGRIKITKIEKKGKGNRRVY 233
|
|
| DHHA1 |
pfam02272 |
DHHA1 domain; This domain is often found adjacent to the DHH domain pfam01368 and is called ... |
820-963 |
2.65e-20 |
|
DHHA1 domain; This domain is often found adjacent to the DHH domain pfam01368 and is called DHHA1 for DHH associated domain. This domain is diagnostic of DHH subfamily 1 members. This domains is also found in alanyl tRNA synthetase, suggesting that this domain may have an RNA binding function. The domain is about 60 residues long and contains a conserved GG motif.
Pssm-ID: 396724 [Multi-domain] Cd Length: 139 Bit Score: 87.88 E-value: 2.65e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 820 DSIREKAKAIQKTLDGYTKAQQAAVAEKVLGEAKELAAVaeqpTVLVHVFAANANSKAIDNALKLLKDT--KAVMAFSVN 897
Cdd:pfam02272 2 ESLNEELKELEKELEELKEALALLKAKELLEKAEEINGV----KVLVAEVGEGWDAGALGIAADRLKKKlgDPVIVLVAK 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 17506981 898 EDSGKVLCLAKVDKSlvsNGLKANEWVNEVCTVLGGKGGGKDaNAQLTGENVDKLDAAVELAQKFA 963
Cdd:pfam02272 78 EDGDKVKVSARSSKD---KGVDAGELLKEVAAILGGGGGGHD-LAAGAGIDAEKLDEALELLEEAI 139
|
|
| PLN02961 |
PLN02961 |
alanine-tRNA ligase |
530-754 |
5.49e-13 |
|
alanine-tRNA ligase
Pssm-ID: 178546 [Multi-domain] Cd Length: 223 Bit Score: 69.34 E-value: 5.49e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 530 AILLDRTNFYAEQGGQIYDVGVLTKVNDESNeFNVSNCQVRGGYIVLVGSAEGS-------FSVGDQVNERFDEDRKQLI 602
Cdd:PLN02961 4 ALVLDRTIFHPQGGGQPSDTGRIVISGGDTK-FSVQDVRRKDGVVYHYGVFEGSnpesaspFEAGDEVTVTVDESRRKLH 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 603 MKNHTGTHVLNYALRKVladsdQKGSLVA------PDRMRFDFTNKAGMTVQQVKKAE--EYAQQLIDTKGQVYAKNSPL 674
Cdd:PLN02961 83 SRLHSAGHLLDVCMARV-----GLGPLEPgkgyhfPDGPFVEYKGKIPQGELDSKQDEleAEANELIAEGGKVSAAVLPY 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 675 GEAKKVKGlRAMFDETYPDPV-RVVAVGtpveqllqnpdaeegqNTTVEFCGGTHLQNVSHIGRIVIaSEEAIAKGIRRI 753
Cdd:PLN02961 158 DEAAELCG-GSLPDYIAKDSTpRIVKIG----------------DSPGCPCGGTHVADVSEITSVKV-TQIRVKKGVTRV 219
|
.
gi 17506981 754 V 754
Cdd:PLN02961 220 S 220
|
|
| tRNA_SAD |
pfam07973 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active from of ... |
695-753 |
1.20e-10 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active from of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 429764 [Multi-domain] Cd Length: 43 Bit Score: 57.07 E-value: 1.20e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 17506981 695 VRVVAVGtpveqllqnpdaeegqNTTVEFCGGTHLQNVSHIGRIVIASEEAIAKGIRRI 753
Cdd:pfam07973 1 VRVVSIG----------------DFDVDLCGGTHVPNTGEIGAFKILKGESKNKGLRRI 43
|
|
| tRNA_SAD |
smart00863 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of ... |
695-753 |
5.70e-10 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this SAD domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 197931 [Multi-domain] Cd Length: 43 Bit Score: 55.47 E-value: 5.70e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 17506981 695 VRVVAVGtpveqllqnpdaeegqNTTVEFCGGTHLQNVSHIGRIVIASEEAIAKGIRRI 753
Cdd:smart00863 1 VRVVSIG----------------DFSVELCGGTHVPNTGEIGAFKILSVSGAYWGLQRI 43
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
760-853 |
1.75e-03 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 42.12 E-value: 1.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 760 EAERAIARADRLTARLEEeskhadKKDELLANKDKFKA-LQKKIQEIVDEAngaqlpywrkdsiREKAKAIQKTLDGYTK 838
Cdd:PRK00409 538 EAEALLKEAEKLKEELEE------KKEKLQEEEDKLLEeAEKEAQQAIKEA-------------KKEADEIIKELRQLQK 598
|
90
....*....|....*
gi 17506981 839 AQQAAVAEKVLGEAK 853
Cdd:PRK00409 599 GGYASVKAHELIEAR 613
|
|
| AtpF |
COG0711 |
FoF1-type ATP synthase, membrane subunit b or b' [Energy production and conversion]; FoF1-type ... |
766-883 |
9.03e-03 |
|
FoF1-type ATP synthase, membrane subunit b or b' [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit b or b' is part of the Pathway/BioSystem: FoF1-type ATP synthase
Pssm-ID: 440475 [Multi-domain] Cd Length: 152 Bit Score: 37.84 E-value: 9.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17506981 766 ARADRLTARLEE-ESKHADKKDELLANKDKFKALQKKIQEIVDEAN--GAQLpywrKDSIREKAKA-IQKTLDgytKAQQ 841
Cdd:COG0711 31 ERQEKIADGLAEaERAKEEAEAALAEYEEKLAEARAEAAEIIAEARkeAEAI----AEEAKAEAEAeAERIIA---QAEA 103
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 17506981 842 AAVAEK------VLGEAKELA-AVAEQptVLVHVFAANANSKAIDNALK 883
Cdd:COG0711 104 EIEQERakalaeLRAEVADLAvAIAEK--ILGKELDAAAQAALVDRFIA 150
|
|
| |
