|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
33-368 |
4.36e-23 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 101.55 E-value: 4.36e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 33 KGSSLRSIPILLDPRTTVLDLSNNRISRLSADELSLYPNLEQLILHNNSITHLSADVFSTLPSLRVLDLSSNSLLSLPNE 112
Cdd:COG4886 28 LLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 113 VFSKLKNLKTLIISSNDVQLGPECFAGLSQLQTLSIADNRLSFLPPSvLKPLSGLRNLDLSANKLLSMPASvMNNLGGLE 192
Cdd:COG4886 108 ELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEP-LGNLTNLKSLDLSNNQLTDLPEE-LGNLTNLK 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 193 TLKLKQNLLSSLetGMFLSQ-KELKHLDVSENLIGDIEEgALYGLEKLETLNLTNNQLVRLPgNTWSLPALKTLDLSSNL 271
Cdd:COG4886 186 ELDLSNNQITDL--PEPLGNlTNLEELDLSGNQLTDLPE-PLANLTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQ 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 272 FVSLETASfdGLPALQYLNISHSR----NLKTIQMATFVQLSSLHWLSISSSALTHIHPSAFNPIPPLSHLDLSNNELRY 347
Cdd:COG4886 262 LTDLPPLA--NLTNLKTLDLSNNQltdlKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTT 339
|
330 340
....*....|....*....|.
gi 17510521 348 VAPGMLQWPNIRNLHLANNDW 368
Cdd:COG4886 340 LALSLSLLALLTLLLLLNLLS 360
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
49-312 |
1.22e-20 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 94.23 E-value: 1.22e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 49 TVLDLSNNRISRLSaDELSLYPNLEQLILHNNSITHLSADvFSTLPSLRVLDLSSNSLLSLPNEvFSKLKNLKTLIISSN 128
Cdd:COG4886 116 ESLDLSGNQLTDLP-EELANLTNLKELDLSNNQLTDLPEP-LGNLTNLKSLDLSNNQLTDLPEE-LGNLTNLKELDLSNN 192
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 129 DVQLGPECFAGLSQLQTLSIADNRLSFLPPSvLKPLSGLRNLDLSANKLLSMPAsvMNNLGGLETLKLKQNLLSSLETGM 208
Cdd:COG4886 193 QITDLPEPLGNLTNLEELDLSGNQLTDLPEP-LANLTNLETLDLSNNQLTDLPE--LGNLTNLEELDLSNNQLTDLPPLA 269
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 209 FLSQkeLKHLDVSENLIGDIEEGALYGLEKLETLNLTNNQLVRLPGNTWSLPALKTLDLSSNLFVSLETASFDGLPALQY 288
Cdd:COG4886 270 NLTN--LKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLL 347
|
250 260
....*....|....*....|....
gi 17510521 289 LNISHSRNLKTIQMATFVQLSSLH 312
Cdd:COG4886 348 ALLTLLLLLNLLSLLLTLLLTLGL 371
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
117-366 |
3.17e-15 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 77.67 E-value: 3.17e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 117 LKNLKTLIISSNDVQLGPECFAGLSQLQTLSIADNRLSFLPPSVLKPLSGLRNLDLSANKLLSMPASvmNNLGGLETLKL 196
Cdd:COG4886 2 LLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLL--LSLLLLLLLSL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 197 KQNLLSSLETGMFLSQKELKHLDVSENligdieeGALYGLEKLETLNLTNNQLVRLPGNTWSLPALKTLDLSSNLFVSLE 276
Cdd:COG4886 80 LLLSLLLLGLTDLGDLTNLTELDLSGN-------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLP 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 277 tASFDGLPALQYLNISHSRnLKTIQmATFVQLSSLHWLSISSSALTHIhPSAFNPIPPLSHLDLSNNELRYVAPGMLQWP 356
Cdd:COG4886 153 -EPLGNLTNLKSLDLSNNQ-LTDLP-EELGNLTNLKELDLSNNQITDL-PEPLGNLTNLEELDLSGNQLTDLPEPLANLT 228
|
250
....*....|
gi 17510521 357 NIRNLHLANN 366
Cdd:COG4886 229 NLETLDLSNN 238
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
22-295 |
8.24e-15 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 77.43 E-value: 8.24e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 22 CKCPTKTTAVCKGSSLRSIPILLDPRTTVLDLSNNRISRLSADelsLYPNLEQLILHNNSITHLSAdvfsTLP-SLRVLD 100
Cdd:PRK15370 175 CLKNNKTELRLKILGLTTIPACIPEQITTLILDNNELKSLPEN---LQGNIKTLYANSNQLTSIPA----TLPdTIQEME 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 101 LSSNSLLSLPNEVFSKLKnlkTLIISSNDVQLGPECFAglSQLQTLSIADNRLSFLPPSVlkPlSGLRNLDLSANKLLSM 180
Cdd:PRK15370 248 LSINRITELPERLPSALQ---SLDLFHNKISCLPENLP--EELRYLSVYDNSIRTLPAHL--P-SGITHLNVQSNSLTAL 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 181 PASVMNNLgglETLKLKQNLLSSLETGMflsQKELKHLDVSENLIGDIEEgalyglekletlnltnnqlvRLPgntwslP 260
Cdd:PRK15370 320 PETLPPGL---KTLEAGENALTSLPASL---PPELQVLDVSKNQITVLPE--------------------TLP------P 367
|
250 260 270
....*....|....*....|....*....|....*.
gi 17510521 261 ALKTLDLSSNLFVSLEtasfDGLP-ALQYLNISHSR 295
Cdd:PRK15370 368 TITTLDVSRNALTNLP----ENLPaALQIMQASRNN 399
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
49-290 |
2.37e-13 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 71.89 E-value: 2.37e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 49 TVLDLSNNRISRLSAdELSLYPNLEQLILHNNSITHLSaDVFSTLPSLRVLDLSSNSLLSLPNEvFSKLKNLKTLIISSN 128
Cdd:COG4886 162 KSLDLSNNQLTDLPE-ELGNLTNLKELDLSNNQITDLP-EPLGNLTNLEELDLSGNQLTDLPEP-LANLTNLETLDLSNN 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 129 DVQLGPEcFAGLSQLQTLSIADNRLSFLPPsvLKPLSGLRNLDLSANKLLSMPASVMNNLGGLETLKLKQNLLSSLETGM 208
Cdd:COG4886 239 QLTDLPE-LGNLTNLEELDLSNNQLTDLPP--LANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLI 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 209 FLSQKELKHLDVSENLIGDIEEGALYGLEKLETLNLTNNQLVRLPGNTWSLPALKTLDLSSNLFVSLETASFDGLPALQY 288
Cdd:COG4886 316 LLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLT 395
|
..
gi 17510521 289 LN 290
Cdd:COG4886 396 TT 397
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
39-410 |
3.22e-12 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 69.49 E-value: 3.22e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 39 SIPILLDPRTTVLDLSNNRISRLSADELSLYPNLEQLILHNN--------SITHLSADVFSTLPSLRVldlssnsLLSLP 110
Cdd:PLN00113 133 SIPRGSIPNLETLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNvlvgkipnSLTNLTSLEFLTLASNQL-------VGQIP 205
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 111 NEVfSKLKNLKTLIISSNDVQLG-PECFAGLSQLQTLSIADNRLSFLPPSVLKPLSGLRNLDLSANKLL-SMPASVMnNL 188
Cdd:PLN00113 206 REL-GQMKSLKWIYLGYNNLSGEiPYEIGGLTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSgPIPPSIF-SL 283
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 189 GGLETLKLKQNLLSSL--ETGMFLSQKELKHLdVSENLIGDIeEGALYGLEKLETLNLTNNQLV-RLPGNTWSLPALKTL 265
Cdd:PLN00113 284 QKLISLDLSDNSLSGEipELVIQLQNLEILHL-FSNNFTGKI-PVALTSLPRLQVLQLWSNKFSgEIPKNLGKHNNLTVL 361
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 266 DLSSN---------------LF-VSLETASFDG-LPAlqylNISHSRNLKTIQM----------ATFVQLSSLHWLSISS 318
Cdd:PLN00113 362 DLSTNnltgeipeglcssgnLFkLILFSNSLEGeIPK----SLGACRSLRRVRLqdnsfsgelpSEFTKLPLVYFLDISN 437
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 319 SALTHIHPSAFNPIPPLSHLDLSNNELRYVAPGMLQWPNIRNLHLANNDWHCSCDLRVSNLNPRDDAKCSGPEnLAGAPI 398
Cdd:PLN00113 438 NNLQGRINSRKWDMPSLQMLSLARNKFFGGLPDSFGSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENK-LSGEIP 516
|
410
....*....|..
gi 17510521 399 NELSSCSILGGL 410
Cdd:PLN00113 517 DELSSCKKLVSL 528
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
47-270 |
5.88e-11 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 62.50 E-value: 5.88e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 47 RTTVLDLSNNRISRLsaDELSLYPNLEQLILHNNSIThlsadvfstlpslrvldlssnsllslpnevfsKLKNLKTliis 126
Cdd:cd21340 3 RITHLYLNDKNITKI--DNLSLCKNLKVLYLYDNKIT--------------------------------KIENLEF---- 44
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 127 sndvqlgpecfagLSQLQTLSIADNRLSFLPPsvLKPLSGLRNLDLSANKLlsmpaSVMNNLGG---LETLKL-KQNL-- 200
Cdd:cd21340 45 -------------LTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRI-----SVVEGLENltnLEELHIeNQRLpp 104
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 17510521 201 ---LSSLETGMFLSQKELKHLDVSENLIGDIEEgaLYGLEKLETLNLTNNQLVRLPGNTW---SLPALKTLDLSSN 270
Cdd:cd21340 105 gekLTFDPRSLAALSNSLRVLNISGNNIDSLEP--LAPLRNLEQLDASNNQISDLEELLDllsSWPSLRELDLTGN 178
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
51-371 |
7.12e-11 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 65.25 E-value: 7.12e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 51 LDLSNNRISRLSADELSLYPNLEQLILHNNSIT-HLSADVFSTLPSLRVLDLSSNSLLSLPnEVFSKLKNLKTLIISSND 129
Cdd:PLN00113 241 LDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSgPIPPSIFSLQKLISLDLSDNSLSGEIP-ELVIQLQNLEILHLFSNN 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 130 VQLG-PECFAGLSQLQTLSIADNRLSFLPPSVLKPLSGLRNLDLSANKLL---------------------SMPASVMNN 187
Cdd:PLN00113 320 FTGKiPVALTSLPRLQVLQLWSNKFSGEIPKNLGKHNNLTVLDLSTNNLTgeipeglcssgnlfklilfsnSLEGEIPKS 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 188 LG---GLETLKLKQNLLSSLETGMFLSQKELKHLDVSEN-LIGDIEEGAlYGLEKLETLNLTNNQLV-RLPGNTWSlPAL 262
Cdd:PLN00113 400 LGacrSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNnLQGRINSRK-WDMPSLQMLSLARNKFFgGLPDSFGS-KRL 477
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 263 KTLDLSSNLFVSLETASFDGLPALQYLNISHSRNLKTIQMatfvQLSS---LHWLSISSSALTHIHPSAFNPIPPLSHLD 339
Cdd:PLN00113 478 ENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPD----ELSSckkLVSLDLSHNQLSGQIPASFSEMPVLSQLD 553
|
330 340 350
....*....|....*....|....*....|....*
gi 17510521 340 LSNNELRYVAPGMLQwpNIRNL---HLANNDWHCS 371
Cdd:PLN00113 554 LSQNQLSGEIPKNLG--NVESLvqvNISHNHLHGS 586
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
35-275 |
1.83e-10 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 63.56 E-value: 1.83e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 35 SSLRSIPILLDPRTTVLDLSNNRISRLSadelslypnleqlilhnnsithlsadvfSTLPSLrvldlssnsllslpnevf 114
Cdd:PRK15370 230 NQLTSIPATLPDTIQEMELSINRITELP----------------------------ERLPSA------------------ 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 115 sklknLKTLIISSNDVQLGPECFAglSQLQTLSIADNRLSFLPPSVlkPlSGLRNLDLSANKLLSMPASVMNNlggLETL 194
Cdd:PRK15370 264 -----LQSLDLFHNKISCLPENLP--EELRYLSVYDNSIRTLPAHL--P-SGITHLNVQSNSLTALPETLPPG---LKTL 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 195 KLKQNLLSSLETGMflsQKELKHLDVSENLIGDIEEGAlygLEKLETLNLTNNQLVRLPGNtwsLP-ALKTLDLSSNLFV 273
Cdd:PRK15370 331 EAGENALTSLPASL---PPELQVLDVSKNQITVLPETL---PPTITTLDVSRNALTNLPEN---LPaALQIMQASRNNLV 401
|
..
gi 17510521 274 SL 275
Cdd:PRK15370 402 RL 403
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
190-249 |
9.22e-10 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 54.45 E-value: 9.22e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 190 GLETLKLKQNLLSSLETGMFLSQKELKHLDVSENLIGDIEEGALYGLEKLETLNLTNNQL 249
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
238-295 |
1.01e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 51.76 E-value: 1.01e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 17510521 238 KLETLNLTNNQLVRLPGNTWS-LPALKTLDLSSNLFVSLETASFDGLPALQYLNISHSR 295
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKgLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNR 60
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
214-272 |
1.32e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 51.37 E-value: 1.32e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 214 ELKHLDVSENLIGDIEEGALYGLEKLETLNLTNNQLVRLPGNTWS-LPALKTLDLSSNLF 272
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSgLPSLRYLDLSGNRL 61
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
49-249 |
3.21e-08 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 56.39 E-value: 3.21e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 49 TVLDLSNNRISRLSADELSLYPNLEQLILHNNSITHLSADVFSTLPSL-RVLDLSSNSLLSLPNEvFSKLKNLKTLIISS 127
Cdd:PLN00113 359 TVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLEGEIPKSLGACRSLrRVRLQDNSFSGELPSE-FTKLPLVYFLDISN 437
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 128 NDVQ-----------------------LG--PECFaGLSQLQTLSIADNRLSFLPPSVLKPLSGLRNLDLSANKLLSMPA 182
Cdd:PLN00113 438 NNLQgrinsrkwdmpslqmlslarnkfFGglPDSF-GSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIP 516
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 17510521 183 SVMNNLGGLETLKLKQNLLSSLETGMFLSQKELKHLDVSEN-LIGDIEEGaLYGLEKLETLNLTNNQL 249
Cdd:PLN00113 517 DELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNqLSGEIPKN-LGNVESLVQVNISHNHL 583
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
119-177 |
4.15e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 49.83 E-value: 4.15e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 119 NLKTLIISSNDVQ-LGPECFAGLSQLQTLSIADNRLSFLPPSVLKPLSGLRNLDLSANKL 177
Cdd:pfam13855 2 NLRSLDLSNNRLTsLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
47-345 |
8.06e-08 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 55.24 E-value: 8.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 47 RTTVLDLSNNRIS-RLSADELSLyPNLEQLILHNNSIT-HLSADVFSTLPSLRVLdlssnsllslpnevfsklkNLktli 124
Cdd:PLN00113 70 RVVSIDLSGKNISgKISSAIFRL-PYIQTINLSNNQLSgPIPDDIFTTSSSLRYL-------------------NL---- 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 125 isSNDVQLGPECFAGLSQLQTLSIADNRLSFLPPSVLKPLSGLRNLDLSANKLLSMPASVMNNLGGLETLKLKQNLLSS- 203
Cdd:PLN00113 126 --SNNNFTGSIPRGSIPNLETLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGq 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 204 --LETGMFLSQK---------------------ELKHLD-VSENLIGDIEEgALYGLEKLETLNLTNNQLV-RLPGNTWS 258
Cdd:PLN00113 204 ipRELGQMKSLKwiylgynnlsgeipyeiggltSLNHLDlVYNNLTGPIPS-SLGNLKNLQYLFLYQNKLSgPIPPSIFS 282
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 259 LPALKTLDLSSNlFVSLETASFdgLPALQYLNISH--SRNLKTIQMATFVQLSSLHWLSISSSALTHIHPSAFNPIPPLS 336
Cdd:PLN00113 283 LQKLISLDLSDN-SLSGEIPEL--VIQLQNLEILHlfSNNFTGKIPVALTSLPRLQVLQLWSNKFSGEIPKNLGKHNNLT 359
|
....*....
gi 17510521 337 HLDLSNNEL 345
Cdd:PLN00113 360 VLDLSTNNL 368
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
213-366 |
1.63e-07 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 52.10 E-value: 1.63e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 213 KELKHLDVSENLIGDIEegALYGLEKLETLNLTNNQLVRLPgNTWSLPALKTLDLSSNLFVSLEtaSFDGLPALQYLNIS 292
Cdd:cd21340 24 KNLKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEKIE-NLENLVNLKKLYLGGNRISVVE--GLENLTNLEELHIE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 293 H------------SRNLKTIQmatfvqlSSLHWLSISSSALTHIHPsaFNPIPPLSHLDLSNNELR---YVAPGMLQWPN 357
Cdd:cd21340 99 NqrlppgekltfdPRSLAALS-------NSLRVLNISGNNIDSLEP--LAPLRNLEQLDASNNQISdleELLDLLSSWPS 169
|
....*....
gi 17510521 358 IRNLHLANN 366
Cdd:cd21340 170 LRELDLTGN 178
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
284-345 |
4.45e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 47.13 E-value: 4.45e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 17510521 284 PALQYLNISHSRnLKTIQMATFVQLSSLHWLSISSSALTHIHPSAFNPIPPLSHLDLSNNEL 345
Cdd:pfam13855 1 PNLRSLDLSNNR-LTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
309-367 |
1.16e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.59 E-value: 1.16e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 309 SSLHWLSISSSALTHIHPSAFNPIPPLSHLDLSNNELRYVAPGMLQ-WPNIRNLHLANND 367
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSgLPSLRYLDLSGNR 60
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
43-270 |
2.93e-06 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 49.79 E-value: 2.93e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 43 LLDPRTTVLDLSNNRIS----RLSADELSLYPNLEQLILHNNSITHLSADVFStlpslrvldlssnsllslpnEVFSKLK 118
Cdd:COG5238 177 LQNNSVETVYLGCNQIGdegiEELAEALTQNTTVTTLWLKRNPIGDEGAEILA--------------------EALKGNK 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 119 NLKTLIISSNdvQLGPECFAGLSQlqtlsiadnrlsflppsVLKPLSGLRNLDLSANKLlsmpasvmnnlgGLETLKLKQ 198
Cdd:COG5238 237 SLTTLDLSNN--QIGDEGVIALAE-----------------ALKNNTTVETLYLSGNQI------------GAEGAIALA 285
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 199 NLLSSletgmflsQKELKHLDVSENLIGDieEGALY---GLEK---LETLNLTNNQL-----VRLPGNTWSLPALKTLDL 267
Cdd:COG5238 286 KALQG--------NTTLTSLDLSVNRIGD--EGAIAlaeGLQGnktLHTLNLAYNGIgaqgaIALAKALQENTTLHSLDL 355
|
...
gi 17510521 268 SSN 270
Cdd:COG5238 356 SDN 358
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
46-97 |
5.17e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 44.05 E-value: 5.17e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 17510521 46 PRTTVLDLSNNRISRLSADELSLYPNLEQLILHNNSITHLSADVFSTLPSLR 97
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLR 52
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
141-201 |
4.85e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 41.36 E-value: 4.85e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17510521 141 SQLQTLSIADNRLSFLPPSVLKPLSGLRNLDLSANKLLSMPASVMNNLGGLETLKLKQNLL 201
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
141-270 |
1.22e-04 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 44.27 E-value: 1.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 141 SQLQTLSIADNRLS-----FLPPSVLKPLSGLRNLDLSANKLLSMP----ASVMNNLGGLETLKLKQNLLS-----SLET 206
Cdd:cd00116 108 SSLQELKLNNNGLGdrglrLLAKGLKDLPPALEKLVLGRNRLEGAScealAKALRANRDLKELNLANNGIGdagirALAE 187
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 17510521 207 GmFLSQKELKHLDVSENLIGDIEEGALYG----LEKLETLNLTNNQLVR------LPGNTWSLPALKTLDLSSN 270
Cdd:cd00116 188 G-LKANCNLEVLDLNNNGLTDEGASALAEtlasLKSLEVLNLGDNNLTDagaaalASALLSPNISLLTLSLSCN 260
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
41-97 |
1.35e-04 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 43.24 E-value: 1.35e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 17510521 41 PILLDPRT--------TVLDLSNNRISRLSadELSLYPNLEQLILHNNSITHLS--ADVFSTLPSLR 97
Cdd:cd21340 107 KLTFDPRSlaalsnslRVLNISGNNIDSLE--PLAPLRNLEQLDASNNQISDLEelLDLLSSWPSLR 171
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
50-177 |
2.14e-04 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 43.50 E-value: 2.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 50 VLDLSNNRIS----RLSADEL-SLYPNLEQLILHNNSITHLS----ADVFSTLPSLRVLDLS----SNSLLSLPNEVFSK 116
Cdd:cd00116 112 ELKLNNNGLGdrglRLLAKGLkDLPPALEKLVLGRNRLEGAScealAKALRANRDLKELNLAnngiGDAGIRALAEGLKA 191
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 17510521 117 LKNLKTLIISSN------DVQLGpECFAGLSQLQTLSIADNRLSF-----LPPSVLKPLSGLRNLDLSANKL 177
Cdd:cd00116 192 NCNLEVLDLNNNgltdegASALA-ETLASLKSLEVLNLGDNNLTDagaaaLASALLSPNISLLTLSLSCNDI 262
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
70-130 |
5.83e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 38.27 E-value: 5.83e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17510521 70 PNLEQLILHNNSITHLSADVFSTLPSLRVLDLSSNSLLSLPNEVFSKLKNLKTLIISSNDV 130
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
143-367 |
1.17e-03 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 41.19 E-value: 1.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 143 LQTLSIADNRLSFLPPSVLKPLSGLRN------LDLSANKLLSMPASVMNNL---GGLETLKLKQNLLSslETGMFLSQK 213
Cdd:cd00116 53 LKELCLSLNETGRIPRGLQSLLQGLTKgcglqeLDLSDNALGPDGCGVLESLlrsSSLQELKLNNNGLG--DRGLRLLAK 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 214 ELKH-------LDVSENLI--GDIEE--GALYGLEKLETLNLTNNQLvRLPGNTW------SLPALKTLDLSSNLFVSLE 276
Cdd:cd00116 131 GLKDlppalekLVLGRNRLegASCEAlaKALRANRDLKELNLANNGI-GDAGIRAlaeglkANCNLEVLDLNNNGLTDEG 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 277 TASFDG----LPALQYLNISHSrnlktiqmatfvqlsslhwlSISSSALTHIHPSAFNPIPPLSHLDLSNNELRYVAPGM 352
Cdd:cd00116 210 ASALAEtlasLKSLEVLNLGDN--------------------NLTDAGAAALASALLSPNISLLTLSLSCNDITDDGAKD 269
|
250 260
....*....|....*....|
gi 17510521 353 L-----QWPNIRNLHLANND 367
Cdd:cd00116 270 LaevlaEKESLLELDLRGNK 289
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
68-368 |
2.78e-03 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 40.53 E-value: 2.78e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 68 LYPNLEQLILHNNSITHLSAdvfsTLPSLRVLDLSSNSLLSLPnevfSKLKNLKTLIISSNDVQLGPECFAGLSQLQtls 147
Cdd:PRK15387 220 LPAHITTLVIPDNNLTSLPA----LPPELRTLEVSGNQLTSLP----VLPPGLLELSIFSNPLTHLPALPSGLCKLW--- 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 148 IADNRLSFLPpsVLKPlsGLRNLDLSANKLLSMPAsVMNNLGGLETLKLKQNLLSSLETGmflsqkeLKHLDVSENLIGD 227
Cdd:PRK15387 289 IFGNQLTSLP--VLPP--GLQELSVSDNQLASLPA-LPSELCKLWAYNNQLTSLPTLPSG-------LQELSVSDNQLAS 356
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17510521 228 IEEGAlyglEKLETLNLTNNQLVRLPgntwSLPA-LKTLDLSSNLFVSLETA------------SFDGLPALQ--YLNIS 292
Cdd:PRK15387 357 LPTLP----SELYKLWAYNNRLTSLP----ALPSgLKELIVSGNRLTSLPVLpselkelmvsgnRLTSLPMLPsgLLSLS 428
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 17510521 293 HSRNLKTIQMATFVQLSSLHWLSISSSALTHIHPSAFNPIPplSHLDLSNNELRYVAPGMLQWPNIRNLHLANNDW 368
Cdd:PRK15387 429 VYRNQLTRLPESLIHLSSETTVNLEGNPLSERTLQALREIT--SAPGYSGPIIRFDMAGASAPRETRALHLAAADW 502
|
|
|