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Conserved domains on  [gi|392884790|ref|NP_490874|]
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Mucin-5AC [Caenorhabditis elegans]

Protein Classification

thrombospondin type-1 domain-containing protein( domain architecture ID 10641280)

thrombospondin type-1 (TSP1) domain-containing protein similar to Mus musculus thrombospondin type-1 domain-containing protein 1, which is a positive regulator of nascent focal adhesion assembly, involved in the modulation of endothelial cell attachment to the extracellular matrix

CATH:  2.20.100.10
SCOP:  4003415

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 62-102 3.20e-07

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


:

Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 47.58  E-value: 3.20e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 392884790    62 WAAWSAWSFCSDS----HRIRVRACN----TVRGFRCLGPNQQTEACDP 102
Cdd:smart00209   1 WSEWSEWSPCSVTcgggVQTRTRSCCspppQNGGGPCTGEDVETRACNE 49
 
Name Accession Description Interval E-value
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 62-102 3.20e-07

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 47.58  E-value: 3.20e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 392884790    62 WAAWSAWSFCSDS----HRIRVRACN----TVRGFRCLGPNQQTEACDP 102
Cdd:smart00209   1 WSEWSEWSPCSVTcgggVQTRTRSCCspppQNGGGPCTGEDVETRACNE 49
TSP_1 pfam00090
Thrombospondin type 1 domain;
60-100 4.69e-04

Thrombospondin type 1 domain;


Pssm-ID: 459668 [Multi-domain]  Cd Length: 49  Bit Score: 38.55  E-value: 4.69e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 392884790   60 SVWAAWSAWSF-CSDSHRIRVRACN--TVRGFRCLGPNQQTEAC 100
Cdd:pfam00090   1 SPWSPWSPCSVtCGKGIQVRQRTCKspFPGGEPCTGDDIETQAC 44
 
Name Accession Description Interval E-value
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 62-102 3.20e-07

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 47.58  E-value: 3.20e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 392884790    62 WAAWSAWSFCSDS----HRIRVRACN----TVRGFRCLGPNQQTEACDP 102
Cdd:smart00209   1 WSEWSEWSPCSVTcgggVQTRTRSCCspppQNGGGPCTGEDVETRACNE 49
TSP_1 pfam00090
Thrombospondin type 1 domain;
60-100 4.69e-04

Thrombospondin type 1 domain;


Pssm-ID: 459668 [Multi-domain]  Cd Length: 49  Bit Score: 38.55  E-value: 4.69e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 392884790   60 SVWAAWSAWSF-CSDSHRIRVRACN--TVRGFRCLGPNQQTEAC 100
Cdd:pfam00090   1 SPWSPWSPCSVtCGKGIQVRQRTCKspFPGGEPCTGDDIETQAC 44
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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