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Concise Results
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phosphoribosylformylglycinamidine synthase, isoform A [Drosophila melanogaster]
Protein Classification
List of domain hits
Name
Accession
Description
Interval
E-value
PLN03206 super family
cl31983 phosphoribosylformylglycinamidine synthase; Provisional
18-1349
0e+00
phosphoribosylformylglycinamidine synthase; Provisional
PLN03206 :Pssm-ID: 178745 [Multi-domain]
Cd Length: 1307
Bit Score: 1643.72
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 18 ESV LR RLREEDG - AV VS VRM E R C YHLEY sa QAEH S LALD E L L V WL VKQP ----- L SKGQS L SRQP alq S T G SSQLLL E I G 91
Cdd:PLN03206 1 AEL LR KVQTKVS n DI VS IET E Q C FNVGL -- ESPL S AEKL E T L K WL LRET fepen L GTESF L EAKK --- S E G LNAVVV E V G 75
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 92 PR FN F S T PY STN C V N I FQNL G YS EV R R M E T S T RYL VTFGEGSKAPEAAR F VPLLG DRMT Q C L Y TE ent P KA SF DEQL - PE 170
Cdd:PLN03206 76 PR LS F T T AW STN A V S I CSAC G LT EV T R L E R S R RYL LFSSSPLDESQINA F AAMVH DRMT E C V Y PQ --- P LT SF ESGV v PE 152
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 171 RQ anw HF VPV L EEGRAALE R IN Q E L GLAF NDY DLDYY HD LF AKELG R N PT T VELFD C AQSNSEHSRHWFF R G RM VIDG VE 250
Cdd:PLN03206 153 PV --- YT VPV M EEGRAALE E IN K E M GLAF DEQ DLDYY TR LF RDDIK R D PT N VELFD I AQSNSEHSRHWFF S G KL VIDG QP 229
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 251 Q PK S L IR M IM DT QA h T NPNN - T I K F S DNSSA MV GF DH Q TIV P S S VVA P GAVRLQSVQS D LIF TAETHN M P T AVAP FS GA T 329
Cdd:PLN03206 230 M PK T L FQ M VK DT LK - A NPNN s V I G F K DNSSA IR GF VV Q PLR P V S PGS P SPLAPVDRDL D ILL TAETHN F P C AVAP YP GA E 308
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 330 TG T GGR L RD VQGV GRG GVPI AGTAGYCVG A L H I P G YKQ P Y E PLD F K YP ATF A P PLQ V LI E ASNGASDYGNKFGEP V I S G F 409
Cdd:PLN03206 309 TG A GGR I RD THAT GRG SFVV AGTAGYCVG N L R I E G SYA P W E DSS F V YP SNL A S PLQ I LI D ASNGASDYGNKFGEP L I Q G Y 388
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 410 ALSY G LNSA ad ASQ R D E YV KPIMFSGG L G TMPA T MRE K LP P AR G Q L LA KIGGP V YRIG V GGGAASS V e IQ G SG DAELDFN 489
Cdd:PLN03206 389 TRTF G MRLP -- NGE R R E WL KPIMFSGG I G QIDH T HLT K GE P DI G M L VV KIGGP A YRIG M GGGAASS M - VS G QN DAELDFN 465
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 490 AVQRGDAEM EN KL N RVVRAC LDL GE Q NPI LA IHDQGAGGN G NV L KE LVE P gf A GA V I FSKEFQL GD P T ITA LE L WGAEYQ 569
Cdd:PLN03206 466 AVQRGDAEM SQ KL Y RVVRAC VEM GE D NPI VS IHDQGAGGN C NV V KE IIY P -- K GA E I DIRAVVV GD H T LSV LE I WGAEYQ 543
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 570 E NN A I L CNADQ R E LL EK IC R RERC PISFV G VVT G D GRV T L LEKP AP KDL E qaln A SNRSEVS P - F DL E L KY VLGDMP KR T 648
Cdd:PLN03206 544 E QD A L L IKPES R D LL QS IC D RERC SMAVI G TID G S GRV V L VDSA AP EKC E ---- A NGLPPPP P a V DL D L EK VLGDMP QK T 619
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 649 YDL KR EQTP L KE L SL P K G LLLDE AL E RVL S L VA V G SKRFLT N KVDRCV G GL I AQQQ C VGPLQ A PLAD Y A LTTVS H FSHS G 728
Cdd:PLN03206 620 FEF KR VANK L EP L DI P P G ITVMD AL K RVL R L PS V C SKRFLT T KVDRCV T GL V AQQQ T VGPLQ I PLAD V A VIAQT H TGLT G 699
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 729 I A TS IG T QP L KGL L DP A AMAR MC V A EAL S NLV FV K ISE L A DVK C SGNWM W AAKL P GEGA R M F DA CKE L CQILE EL HI AID 808
Cdd:PLN03206 700 G A CA IG E QP I KGL V DP K AMAR LA V G EAL T NLV WA K VTA L S DVK A SGNWM Y AAKL D GEGA D M Y DA AVA L RDAMI EL GV AID 779
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 809 GGKDSLSMAA KV GGE TI K S PG T LVIS T Y AP CPD VRLK VTPDLK GPGA G skt S LL WIN L EN - SA RLGGSALAQAY A Q Q G K D 887
Cdd:PLN03206 780 GGKDSLSMAA QA GGE VV K A PG N LVIS A Y VT CPD ITKT VTPDLK LGDD G --- V LL HVD L GK g KR RLGGSALAQAY D Q I G D D 856
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 888 T P N L TRSDV L G KAF AV TQ S L LGDG LI Q AGHD V SDGGL L V CV LEMA IG G LS G LR VDL SEP laklknfdksvekl NRPELAV 967
Cdd:PLN03206 857 C P D L DDVAY L K KAF EA TQ D L IAKR LI S AGHD I SDGGL V V TL LEMA FA G NC G IN VDL PSS -------------- GHSAFET 922
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 968 LFAEE C G W V V EV LDTD L ER V RSTYEK AGV PNYYL G - VT EG fgld SRVVL K NGKSEL L DQPLRV L YKK WE R TS YE LEKLQ A 1046
Cdd:PLN03206 923 LFAEE L G L V L EV SRKN L DA V MEKLAA AGV TAEVI G q VT AS ---- PLIEV K VDGATC L SEKTAS L RDM WE E TS FQ LEKLQ R 998
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1047 NPE C AEA E YNS L EY R Q AP QYR --- G P QNVQAEL t LKRS S A P v R VA VL REEG V N SE REM M A CLLR A N FE VH DVTMSDLL Q G 1123
Cdd:PLN03206 999 LES C VAQ E KEG L KS R K AP TWK lsf T P AFTDKKI - MNAT S K P - K VA II REEG S N GD REM A A AFYA A G FE PW DVTMSDLL N G 1076
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1124 TA S VSQY RG LI F P GGFSYAD T L G SAKGWA AN I LH N PR LL P QF EA F KR R Q D V FSLG I CNGCQLM T L I G F V GSAKSE -- V GA 1201
Cdd:PLN03206 1077 RI S LDDF RG IV F V GGFSYAD V L D SAKGWA GS I RF N EP LL Q QF QE F YN R P D T FSLG V CNGCQLM A L L G W V PGPQVG gg L GA 1156
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1202 DP D VA --- LL HN K S Q RFECR WAT V K I PSNRS IML GS M KDLV LG C W V AHGEGR FA F R DE KLISHLQSEQ L VTLQ Y V DD V G K 1278
Cdd:PLN03206 1157 GG D PS qpr FV HN E S G RFECR FTS V T I EDSPA IML KG M EGST LG V W A AHGEGR AY F P DE SVLDEVLKSN L APVR Y C DD D G E 1236
1290 1300 1310 1320 1330 1340 1350
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17137292 1279 PTE L YP L NPNGSP Q GIA G LCS S DGRHLA L MPHPERC SS M Y Q W P YV P SSFE V S P t QSE SPW QI MF N NA YN WC 1349
Cdd:PLN03206 1237 PTE Q YP F NPNGSP L GIA A LCS P DGRHLA M MPHPERC FL M W Q F P WY P KEWG V D P - AGP SPW LK MF Q NA RE WC 1306
Name
Accession
Description
Interval
E-value
PLN03206
PLN03206 phosphoribosylformylglycinamidine synthase; Provisional
18-1349
0e+00
phosphoribosylformylglycinamidine synthase; Provisional
Pssm-ID: 178745 [Multi-domain]
Cd Length: 1307
Bit Score: 1643.72
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 18 ESV LR RLREEDG - AV VS VRM E R C YHLEY sa QAEH S LALD E L L V WL VKQP ----- L SKGQS L SRQP alq S T G SSQLLL E I G 91
Cdd:PLN03206 1 AEL LR KVQTKVS n DI VS IET E Q C FNVGL -- ESPL S AEKL E T L K WL LRET fepen L GTESF L EAKK --- S E G LNAVVV E V G 75
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 92 PR FN F S T PY STN C V N I FQNL G YS EV R R M E T S T RYL VTFGEGSKAPEAAR F VPLLG DRMT Q C L Y TE ent P KA SF DEQL - PE 170
Cdd:PLN03206 76 PR LS F T T AW STN A V S I CSAC G LT EV T R L E R S R RYL LFSSSPLDESQINA F AAMVH DRMT E C V Y PQ --- P LT SF ESGV v PE 152
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 171 RQ anw HF VPV L EEGRAALE R IN Q E L GLAF NDY DLDYY HD LF AKELG R N PT T VELFD C AQSNSEHSRHWFF R G RM VIDG VE 250
Cdd:PLN03206 153 PV --- YT VPV M EEGRAALE E IN K E M GLAF DEQ DLDYY TR LF RDDIK R D PT N VELFD I AQSNSEHSRHWFF S G KL VIDG QP 229
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 251 Q PK S L IR M IM DT QA h T NPNN - T I K F S DNSSA MV GF DH Q TIV P S S VVA P GAVRLQSVQS D LIF TAETHN M P T AVAP FS GA T 329
Cdd:PLN03206 230 M PK T L FQ M VK DT LK - A NPNN s V I G F K DNSSA IR GF VV Q PLR P V S PGS P SPLAPVDRDL D ILL TAETHN F P C AVAP YP GA E 308
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 330 TG T GGR L RD VQGV GRG GVPI AGTAGYCVG A L H I P G YKQ P Y E PLD F K YP ATF A P PLQ V LI E ASNGASDYGNKFGEP V I S G F 409
Cdd:PLN03206 309 TG A GGR I RD THAT GRG SFVV AGTAGYCVG N L R I E G SYA P W E DSS F V YP SNL A S PLQ I LI D ASNGASDYGNKFGEP L I Q G Y 388
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 410 ALSY G LNSA ad ASQ R D E YV KPIMFSGG L G TMPA T MRE K LP P AR G Q L LA KIGGP V YRIG V GGGAASS V e IQ G SG DAELDFN 489
Cdd:PLN03206 389 TRTF G MRLP -- NGE R R E WL KPIMFSGG I G QIDH T HLT K GE P DI G M L VV KIGGP A YRIG M GGGAASS M - VS G QN DAELDFN 465
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 490 AVQRGDAEM EN KL N RVVRAC LDL GE Q NPI LA IHDQGAGGN G NV L KE LVE P gf A GA V I FSKEFQL GD P T ITA LE L WGAEYQ 569
Cdd:PLN03206 466 AVQRGDAEM SQ KL Y RVVRAC VEM GE D NPI VS IHDQGAGGN C NV V KE IIY P -- K GA E I DIRAVVV GD H T LSV LE I WGAEYQ 543
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 570 E NN A I L CNADQ R E LL EK IC R RERC PISFV G VVT G D GRV T L LEKP AP KDL E qaln A SNRSEVS P - F DL E L KY VLGDMP KR T 648
Cdd:PLN03206 544 E QD A L L IKPES R D LL QS IC D RERC SMAVI G TID G S GRV V L VDSA AP EKC E ---- A NGLPPPP P a V DL D L EK VLGDMP QK T 619
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 649 YDL KR EQTP L KE L SL P K G LLLDE AL E RVL S L VA V G SKRFLT N KVDRCV G GL I AQQQ C VGPLQ A PLAD Y A LTTVS H FSHS G 728
Cdd:PLN03206 620 FEF KR VANK L EP L DI P P G ITVMD AL K RVL R L PS V C SKRFLT T KVDRCV T GL V AQQQ T VGPLQ I PLAD V A VIAQT H TGLT G 699
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 729 I A TS IG T QP L KGL L DP A AMAR MC V A EAL S NLV FV K ISE L A DVK C SGNWM W AAKL P GEGA R M F DA CKE L CQILE EL HI AID 808
Cdd:PLN03206 700 G A CA IG E QP I KGL V DP K AMAR LA V G EAL T NLV WA K VTA L S DVK A SGNWM Y AAKL D GEGA D M Y DA AVA L RDAMI EL GV AID 779
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 809 GGKDSLSMAA KV GGE TI K S PG T LVIS T Y AP CPD VRLK VTPDLK GPGA G skt S LL WIN L EN - SA RLGGSALAQAY A Q Q G K D 887
Cdd:PLN03206 780 GGKDSLSMAA QA GGE VV K A PG N LVIS A Y VT CPD ITKT VTPDLK LGDD G --- V LL HVD L GK g KR RLGGSALAQAY D Q I G D D 856
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 888 T P N L TRSDV L G KAF AV TQ S L LGDG LI Q AGHD V SDGGL L V CV LEMA IG G LS G LR VDL SEP laklknfdksvekl NRPELAV 967
Cdd:PLN03206 857 C P D L DDVAY L K KAF EA TQ D L IAKR LI S AGHD I SDGGL V V TL LEMA FA G NC G IN VDL PSS -------------- GHSAFET 922
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 968 LFAEE C G W V V EV LDTD L ER V RSTYEK AGV PNYYL G - VT EG fgld SRVVL K NGKSEL L DQPLRV L YKK WE R TS YE LEKLQ A 1046
Cdd:PLN03206 923 LFAEE L G L V L EV SRKN L DA V MEKLAA AGV TAEVI G q VT AS ---- PLIEV K VDGATC L SEKTAS L RDM WE E TS FQ LEKLQ R 998
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1047 NPE C AEA E YNS L EY R Q AP QYR --- G P QNVQAEL t LKRS S A P v R VA VL REEG V N SE REM M A CLLR A N FE VH DVTMSDLL Q G 1123
Cdd:PLN03206 999 LES C VAQ E KEG L KS R K AP TWK lsf T P AFTDKKI - MNAT S K P - K VA II REEG S N GD REM A A AFYA A G FE PW DVTMSDLL N G 1076
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1124 TA S VSQY RG LI F P GGFSYAD T L G SAKGWA AN I LH N PR LL P QF EA F KR R Q D V FSLG I CNGCQLM T L I G F V GSAKSE -- V GA 1201
Cdd:PLN03206 1077 RI S LDDF RG IV F V GGFSYAD V L D SAKGWA GS I RF N EP LL Q QF QE F YN R P D T FSLG V CNGCQLM A L L G W V PGPQVG gg L GA 1156
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1202 DP D VA --- LL HN K S Q RFECR WAT V K I PSNRS IML GS M KDLV LG C W V AHGEGR FA F R DE KLISHLQSEQ L VTLQ Y V DD V G K 1278
Cdd:PLN03206 1157 GG D PS qpr FV HN E S G RFECR FTS V T I EDSPA IML KG M EGST LG V W A AHGEGR AY F P DE SVLDEVLKSN L APVR Y C DD D G E 1236
1290 1300 1310 1320 1330 1340 1350
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17137292 1279 PTE L YP L NPNGSP Q GIA G LCS S DGRHLA L MPHPERC SS M Y Q W P YV P SSFE V S P t QSE SPW QI MF N NA YN WC 1349
Cdd:PLN03206 1237 PTE Q YP F NPNGSP L GIA A LCS P DGRHLA M MPHPERC FL M W Q F P WY P KEWG V D P - AGP SPW LK MF Q NA RE WC 1306
FGAM_synt
TIGR01735 phosphoribosylformylglycinamidine synthase, single chain form; This model represents a ...
11-1348
0e+00
phosphoribosylformylglycinamidine synthase, single chain form; This model represents a single-molecule form of phosphoribosylformylglycinamidine synthase, also called FGAM synthase, an enzyme of purine de novo biosynthesis. This form is found mostly in eukaryotes and Proteobacteria. In Bacillus subtilis PurL (FGAM synthase II) and PurQ (FGAM synthase I), homologous to different parts of this model, perform the equivalent function; the unrelated small protein PurS is also required and may be a third subunit. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 188163 [Multi-domain]
Cd Length: 1310
Bit Score: 1481.57
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 11 A H S AAEE E SV L RR L REEDGAVVS V RM E R CY HLEY sa QAEHSLALD E L L V -- W L VKQP L SKG QS lsrq P ALQS tgssql LL 88
Cdd:TIGR01735 7 A L S GFRL E KL L QK L QTKVPELTG V YA E F CY FVGW -- ESALTADEE E K L Q ll L L AGSV L EPP QS ---- P LGRG ------ LL 74
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 89 E I GPR FNFST P Y S TNCVN I FQ N L G YSE V R R M E TST RY LVTFGEGSKAPEA A RFVP LL G DRMT QCLYTE E NTPKAS F DEQL 168
Cdd:TIGR01735 75 E V GPR LGTIS P W S SKATS I AR N C G LAK V D R I E RGR RY YLSGAHPLSEEQE A QAAA LL H DRMT ESVLPH E IEAFEL F SVPE 154
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 169 P E rqa N WHFVP VL EE GR A ALE RI NQELGLA FNDYDL DY YHDL F a K EL G RNP TT VEL FDC AQ S NSEH S RH WF F RGRMV IDG 248
Cdd:TIGR01735 155 P L --- N LTTID VL GG GR L ALE KA NQELGLA LDEDEI DY LTKR F - Q EL Q RNP SD VEL MMF AQ A NSEH C RH KI F NADWI IDG 230
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 249 VE Q P KSL IR MI MD T QAHTNP N NTIKFS DNSS AMV G FDHQTIV P SSVVA P GAVRL Q SVQSDLIFTA ETHN M PTA V APF S GA 328
Cdd:TIGR01735 231 KK Q D KSL FQ MI KS T HEANPE N TVSAYK DNSS VIE G HKVGRLR P DPPTR P EYRQH Q EDLVHILMKV ETHN H PTA I APF P GA 310
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 329 T TG T GG RL RD VQGV GRG GV P I AG TA G Y CV GA L H IPG YK QP Y E P l D F KY P ATF A P PL QVL IEA SN GA SDYG N K FG E P VIS G 408
Cdd:TIGR01735 311 S TG A GG EI RD EGAT GRG AK P K AG LT G F CV SN L N IPG LE QP W E D - P F QK P ERI A S PL DIM IEA PL GA AAFN N E FG R P NLL G 389
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 409 FALSYG L NSAADAS Q RDE Y V KPIM FS GG L G TMP A TMRE K LPPAR G Q LL AKI GGP VYR IG V GGGAASS V e IQ G SGD A E LDF 488
Cdd:TIGR01735 390 YFRTFE L KASLPGG Q VRG Y H KPIM LA GG I G SID A EHIQ K GEIEP G A LL IVL GGP AML IG L GGGAASS M - VS G TNT A D LDF 468
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 489 NA VQRG DA EME NKLNR V VRA C LD LGE Q NPI LA IHD Q GAGG NG N V L K EL VEP G FA GAVI FSKEFQ L G DP TITA LE L W GA E Y 568
Cdd:TIGR01735 469 AS VQRG NP EME RRCQE V IDR C WQ LGE K NPI IS IHD V GAGG LS N A L P EL IHD G GR GAVI DLRAVP L D DP GLSP LE I W CN E S 548
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 569 QE NNAI L CN A DQR E LLEK IC R RERCP ISF VG VV TGDGR V TL LEKPAPKDLE Q ALNA S NRSE v S P F DL E L KYV LG D MPK R T 648
Cdd:TIGR01735 549 QE RYVL L VR A ENL E IFTA IC E RERCP FAV VG TA TGDGR L TL VDDTPVRRNG Q GDAP S HFPN - N P V DL P L EVL LG K MPK M T 627
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 649 YDLK R EQTP L KE L SL P K GL L L D EALERVL S L V AV G SKRFL TNKV DR C VGGL I A QQ Q C VGP L Q A PLAD Y A L T TV S HFSHS G 728
Cdd:TIGR01735 628 RFVQ R KAPM L QP L DI P P GL D L H EALERVL R L P AV A SKRFL ITIG DR S VGGL V A RD Q M VGP W Q T PLAD V A V T AA S FDTYT G 707
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 729 I A TS IG TQ P L K G LLDP A A M AR MC V A EA LS NL VFVKISE L A DVK C S G NWM W AA KL PGE G A RMF DA C K ELCQILEE L H IAI D 808
Cdd:TIGR01735 708 E A MA IG ER P P K A LLDP K A S AR LA V G EA IT NL AAALVGD L S DVK L S A NWM A AA GH PGE D A ALY DA V K AVSELCPA L G IAI P 787
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 809 G GKDSLSM AAKVGG ---- ETIKS PG T LVIS TY AP C PDVR LK VTPDLK GPG ag SKTS LL WIN L - ENSA RLGGSALAQ AYA Q 883
Cdd:TIGR01735 788 V GKDSLSM KTRWQD nget KSVTA PG S LVIS AF AP V PDVR KT VTPDLK HDK -- GDSH LL LVD L g PGKN RLGGSALAQ VFG Q 865
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 884 Q G K D T P N L TRSDV L GKA FAV T Q S L LGD GL IQ A G HD V SDGGL LVCV LEMA IG G LS GL R VDL SEPLAK L knfdksveklnrp 963
Cdd:TIGR01735 866 L G G D C P D L DDPER L KAF FAV M Q G L VAE GL LL A Y HD R SDGGL VTTL LEMA FA G HC GL D VDL DALGDS L ------------- 932
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 964 e L AVLF A EE C G W V VE V LDT DL ER V RSTYEK AG VPNYY LG VTEGF G l DSRVVLKNGKSE LL DQPLRV L YKK WE R TS YE L EK 1043
Cdd:TIGR01735 933 - F AVLF N EE L G A V IQ V AKP DL AA V LELLRA AG LTALI LG IGTPT G - HPMIRISVNGAT LL SEKRSE L RDI WE E TS FQ L QR 1010
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1044 L QA NPECAE A E YNS L EY R QA P QYR ----- GPQNVQ A ELTLKRSSA P v R VA V LRE E GVN SE REM M A CLL RA N FE VH DV T MS 1118
Cdd:TIGR01735 1011 L RD NPECAE E E FEG L RD R DG P GLK lpltf DVNEDI A APFINKGVK P - K VA I LRE Q GVN GD REM A A AFD RA G FE AW DV H MS 1089
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1119 DLL Q G TASVSQY RGL IFP GGFSY A D T LG SA KGWA AN IL H NPRL LP QF E AF KR R Q D V FSLG I CNGCQ LMT - L IGFVG saks 1197
Cdd:TIGR01735 1090 DLL A G RVHLDEF RGL AAC GGFSY G D V LG AG KGWA KS IL F NPRL RD QF Q AF FK R P D T FSLG V CNGCQ MLS n L LEWIP ---- 1165
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1198 ev G ADPDVALLH N K S Q RFE C R W A T V KIPSNR SIML GS M KDLV L GCW VAHGEG RF AF RDEK L ISHLQSEQ L VT L Q Y V DD V G 1277
Cdd:TIGR01735 1166 -- G TENWPHFVR N N S E RFE A R V A S V RVGESP SIML RG M AGSR L PVA VAHGEG YA AF SSPE L QAQADASG L AA L R Y I DD D G 1243
1290 1300 1310 1320 1330 1340 1350
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17137292 1278 K PTE L YPLNPNGSP Q GIAG LC S S DGR HLAL MPHPER CSSMY Q WPYV P SSF evspt QSES PW QIM F N NA Y NW 1348
Cdd:TIGR01735 1244 N PTE A YPLNPNGSP G GIAG IT S C DGR VTIM MPHPER VFRAW Q NSWR P EDW ----- DEDT PW LRL F R NA R NW 1309
PurL1
COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain [Nucleotide transport and ...
181-1047
0e+00
Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain [Nucleotide transport and metabolism]; Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439816 [Multi-domain]
Cd Length: 747
Bit Score: 634.40
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 181 LE E GR A ALE RI N Q ELGLA FN D YDL DY YH dlfa KE LGRNPT T VEL FDCA Q SN SEH SRHWFFRGRM vidgveqp KSL I rmim 260
Cdd:COG0046 6 LE G GR E ALE EA N R ELGLA LS D DEY DY IV ---- EI LGRNPT D VEL GMFS Q MW SEH CSYKSSNALL -------- KSL P ---- 69
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 261 dtqah T NPNNTI - KFS DN SSAMVGF D HQTI V pssvvapgavrlqsvqsdli F TA E T HN M P T A VA P FS GA T TG T GG RL RD V 339
Cdd:COG0046 70 ----- T EGPRVL s GPG DN AGVVDIG D GLAV V -------------------- F KV E S HN H P S A IE P YQ GA A TG V GG II RD I 124
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 340 qg V G R G GV PIAG TAGYCV G A L HI P GYK qpyepldfkypatfap P LQV LI EASN G AS DYGN K FG E P VIS G FALSY glnsaa 419
Cdd:COG0046 125 -- F G M G AR PIAG LDSLRF G N L DQ P PAS ---------------- P RYI LI GVVA G IA DYGN C FG V P TVG G EVRFD ------ 180
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 420 dasqr DE Y V - K P IMFS GG L G TMP A -- TMRE K L P PA r G QLLAKI GGP VY R I G V GG GAAS S V E I qg SG D A ELD FN AVQ R GD A 496
Cdd:COG0046 181 ----- ES Y E g N P LVNA GG V G IIR A dh IFKA K A P GV - G NKVVYV GGP TG R D G I GG ATFA S E E L -- GE D S ELD RP AVQ V GD P 252
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 497 E ME NK L nrv VR A C L D LG EQNP I LA I H D Q GAGG NGNVLK E LVEP G FA GA V I FSKEFQ L GD P TITAL E L W GA E Y QE NNAILC 576
Cdd:COG0046 253 F ME KR L --- IE A I L E LG DTGL I VG I Q D M GAGG LSSASS E MAAK G GL GA E I DLDKVP L RE P GMSPY E I W LS E S QE RMLLVV 329
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 577 NADQR E LL E K I CR R E R C P ISFV G V VT G DGR VTLL --- E KP A pkdleqalnasnrsevspf DL E L KYVL G DM PK RTYDL KR 653
Cdd:COG0046 330 KPEKL E EF E A I FE R W R L P AAVI G E VT D DGR LVVT dhg E TV A ------------------- DL P L DFLA G GA PK YHRPA KR 390
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 654 E q TP L KE L S LP KGLL L D EAL E R V LS LVA V G SK RF L TNKV DR C VGG LIAQQQ cvgplqa PL AD Y A LTT V SH f SHS G I A T S I 733
Cdd:COG0046 391 P - AY L EP L D LP EPID L E EAL L R L LS SPN V A SK EW L YRQY DR E VGG NTVRDP ------- GV AD A A VVR V DG - TYK G L A M S T 461
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 734 G TQ P LKG LLDP A A M ARM C VAEA LS NL VF V KISE LA d VKCSG NW MWAA K l P G E G A RMFD A C K --- EL C Q ile E L H I AIDG G 810
Cdd:COG0046 462 G EN P RYA LLDP Y A G ARM A VAEA AR NL AA V GAEP LA - ITDCL NW GNPE K - P E E M A QLVE A V K gla DA C R --- A L G I PVPS G 536
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 811 KD SL SMAA K V G GET I ks P G T L VI STYAPCP DVR LK VTPDLK GP G agsk TS L LW I N l E NSAR LGGS AL AQ AYA Q Q G KDT P N 890
Cdd:COG0046 537 NV SL YNET K D G KVA I -- P P T P VI GAVGLVD DVR KT VTPDLK KE G ---- DL L YL I G - E TKNE LGGS EY AQ VLG Q L G GEP P D 609
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 891 L t RSDVLGKA F AVT Q S L LGD GLI Q A G HDVSDGGL L V CVL EMA IG G LS G LRV DL SEP laklknfdksvek LNRPEL A V LF A 970
Cdd:COG0046 610 V - DLEAEKAL F EAV Q E L IRE GLI L A A HDVSDGGL A V ALA EMA FA G GL G ADI DL DAL ------------- GDLRPD A A LF S 675
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 17137292 971 E EC G - W VV E V LDT D L E R V RSTYEK AG V P NYYL G VTE G fgl D S R V V LKN G KSE LL DQP L RV L YKK WE R T sye L EK L QA N 1047
Cdd:COG0046 676 E SQ G r A VV Q V APE D A E A V EALLAE AG L P AHVI G TVT G --- D D R L V IRR G GET LL SLS L AE L RDA WE E T --- L PR L RD N 747
GATase_5
pfam13507 CobB/CobQ-like glutamine amidotransferase domain; This family captures members that are not ...
1085-1349
8.48e-134
CobB/CobQ-like glutamine amidotransferase domain; This family captures members that are not found in pfam00310, pfam07685 and pfam13230.
Pssm-ID: 463904 [Multi-domain]
Cd Length: 260
Bit Score: 411.12
E-value: 8.48e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1085 V RVA V LRE E G V N S E R EM M A CLL RA N F EVH DV T MSDLL Q G TA S VSQYR GL IF PGGFSY A D T LGS A KGWAA N IL H NP R L LPQ 1164
Cdd:pfam13507 2 P RVA I LRE P G T N G E Y EM A A AFE RA G F DAV DV H MSDLL S G RV S LDDFQ GL AA PGGFSY G D V LGS G KGWAA S IL F NP K L RDA 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1165 FEAF KR R Q D V FSLGICNGCQL MTLI G FVGSAKSEV g A DPDVA L LH N K S Q RFE C RW AT VKI P - SNR S IM L GS M K dl VL G CW 1243
Cdd:pfam13507 82 FEAF FN R P D T FSLGICNGCQL LSKL G LIPGGEGDL - A ERWPT L TR N D S G RFE S RW VN VKI S e KSP S VF L RG M D -- GS G LP 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1244 VAHGEGRF A FR D E KLISH L QSEQL V T L Q YVD DV G K PTE L YP L NPNGSP Q GIAG L CS S DGR H L A LMPHPER CSSMY QWP YV 1323
Cdd:pfam13507 159 VAHGEGRF V FR S E EVLAR L EANGQ V A L R YVD NA G N PTE E YP F NPNGSP L GIAG I CS P DGR V L G LMPHPER VFRPW QWP HW 238
250 260
....*....|....*....|....*.
gi 17137292 1324 P SSFE vspt QSE SPW QIM F N NA YN W C 1349
Cdd:pfam13507 239 P PGEW ---- EEV SPW LRL F R NA RK W V 260
PurL_repeat1
cd02203 PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. ...
223-612
1.61e-115
PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP, phosphate, and glutamate in the fourth step of the purine biosynthetic pathway. In eukaryotes and Gram-negative bacteria, FGAR-AT is encoded by the purL gene as a multidomain protein with a molecular mass of about 140 kDa. In Gram-positive bacteria and archaea FGAR-AT is a complex of three proteins: PurS, PurL, and PurQ. PurL itself contains two tandem N- and C-terminal domains (four domains altogether). The N-terminal domains bind ATP and are related to the ATP-binding domains of HypE, ThiL, SelD and PurM.
Pssm-ID: 100034 [Multi-domain]
Cd Length: 313
Bit Score: 364.10
E-value: 1.61e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 223 EL FDC AQ SN SEH S RH WF F rgrmvidgveqp KSL IR MI MD tqahtnpnntikfsdnssamvgfdhqtivpssvvapgavrl 302
Cdd:cd02203 1 EL GMF AQ MW SEH C RH KS F ------------ KSL LK MI WA ----------------------------------------- 27
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 303 qsvqsd LI F TA ETHN M P T A VA PF S GA T TG T GG RL RD VQGV G rg GV PIA GTA G YCV G A L H IPGY K qpyepldfky P ATFAP 382
Cdd:cd02203 28 ------ VV F KV ETHN H P S A IE PF G GA A TG V GG II RD ILSM G -- AR PIA LLD G LRF G D L D IPGY E ---------- P KGKLS 89
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 383 P LQV L IEASN G A SDYGN KF G E P VIS G FALSYG lnsaadasqr DE Y VK P IMFS G GL G TM P ATMRE K - LP P AR G Q L LAKI GG 461
Cdd:cd02203 90 P RRI L DGVVA G I SDYGN CI G I P TVG G EVRFDP ---------- SY Y GN P LVNV G CV G IV P KDHIV K s KA P GP G D L VVLV GG 159
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 462 PVY R I G V GG GAA SS V E I q GSGDA ELD FN AVQ R GD AE ME N KL NRVVRACL dlg E QNP I LA I H D Q GAGG NGNVLK E LVEP G F 541
Cdd:cd02203 160 RTG R D G I GG ATF SS K E L - SENSS ELD RP AVQ V GD PF ME K KL QEAILEAR --- E TGL I VG I Q D L GAGG LSSAVS E MAAK G G 235
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17137292 542 A GA V I FSKEFQ L GD P TITAL E L W GA E Y QE NNAILCNADQR E LLEK IC RR E RCPISFV G V VT G DGR VT L LE K 612
Cdd:cd02203 236 L GA E I DLDKVP L RE P GMSPW E I W IS E S QE RMLLVVPPEDL E EFLA IC KK E DLEAAVI G E VT D DGR LR L YY K 306
Name
Accession
Description
Interval
E-value
PLN03206
PLN03206 phosphoribosylformylglycinamidine synthase; Provisional
18-1349
0e+00
phosphoribosylformylglycinamidine synthase; Provisional
Pssm-ID: 178745 [Multi-domain]
Cd Length: 1307
Bit Score: 1643.72
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 18 ESV LR RLREEDG - AV VS VRM E R C YHLEY sa QAEH S LALD E L L V WL VKQP ----- L SKGQS L SRQP alq S T G SSQLLL E I G 91
Cdd:PLN03206 1 AEL LR KVQTKVS n DI VS IET E Q C FNVGL -- ESPL S AEKL E T L K WL LRET fepen L GTESF L EAKK --- S E G LNAVVV E V G 75
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 92 PR FN F S T PY STN C V N I FQNL G YS EV R R M E T S T RYL VTFGEGSKAPEAAR F VPLLG DRMT Q C L Y TE ent P KA SF DEQL - PE 170
Cdd:PLN03206 76 PR LS F T T AW STN A V S I CSAC G LT EV T R L E R S R RYL LFSSSPLDESQINA F AAMVH DRMT E C V Y PQ --- P LT SF ESGV v PE 152
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 171 RQ anw HF VPV L EEGRAALE R IN Q E L GLAF NDY DLDYY HD LF AKELG R N PT T VELFD C AQSNSEHSRHWFF R G RM VIDG VE 250
Cdd:PLN03206 153 PV --- YT VPV M EEGRAALE E IN K E M GLAF DEQ DLDYY TR LF RDDIK R D PT N VELFD I AQSNSEHSRHWFF S G KL VIDG QP 229
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 251 Q PK S L IR M IM DT QA h T NPNN - T I K F S DNSSA MV GF DH Q TIV P S S VVA P GAVRLQSVQS D LIF TAETHN M P T AVAP FS GA T 329
Cdd:PLN03206 230 M PK T L FQ M VK DT LK - A NPNN s V I G F K DNSSA IR GF VV Q PLR P V S PGS P SPLAPVDRDL D ILL TAETHN F P C AVAP YP GA E 308
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 330 TG T GGR L RD VQGV GRG GVPI AGTAGYCVG A L H I P G YKQ P Y E PLD F K YP ATF A P PLQ V LI E ASNGASDYGNKFGEP V I S G F 409
Cdd:PLN03206 309 TG A GGR I RD THAT GRG SFVV AGTAGYCVG N L R I E G SYA P W E DSS F V YP SNL A S PLQ I LI D ASNGASDYGNKFGEP L I Q G Y 388
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 410 ALSY G LNSA ad ASQ R D E YV KPIMFSGG L G TMPA T MRE K LP P AR G Q L LA KIGGP V YRIG V GGGAASS V e IQ G SG DAELDFN 489
Cdd:PLN03206 389 TRTF G MRLP -- NGE R R E WL KPIMFSGG I G QIDH T HLT K GE P DI G M L VV KIGGP A YRIG M GGGAASS M - VS G QN DAELDFN 465
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 490 AVQRGDAEM EN KL N RVVRAC LDL GE Q NPI LA IHDQGAGGN G NV L KE LVE P gf A GA V I FSKEFQL GD P T ITA LE L WGAEYQ 569
Cdd:PLN03206 466 AVQRGDAEM SQ KL Y RVVRAC VEM GE D NPI VS IHDQGAGGN C NV V KE IIY P -- K GA E I DIRAVVV GD H T LSV LE I WGAEYQ 543
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 570 E NN A I L CNADQ R E LL EK IC R RERC PISFV G VVT G D GRV T L LEKP AP KDL E qaln A SNRSEVS P - F DL E L KY VLGDMP KR T 648
Cdd:PLN03206 544 E QD A L L IKPES R D LL QS IC D RERC SMAVI G TID G S GRV V L VDSA AP EKC E ---- A NGLPPPP P a V DL D L EK VLGDMP QK T 619
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 649 YDL KR EQTP L KE L SL P K G LLLDE AL E RVL S L VA V G SKRFLT N KVDRCV G GL I AQQQ C VGPLQ A PLAD Y A LTTVS H FSHS G 728
Cdd:PLN03206 620 FEF KR VANK L EP L DI P P G ITVMD AL K RVL R L PS V C SKRFLT T KVDRCV T GL V AQQQ T VGPLQ I PLAD V A VIAQT H TGLT G 699
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 729 I A TS IG T QP L KGL L DP A AMAR MC V A EAL S NLV FV K ISE L A DVK C SGNWM W AAKL P GEGA R M F DA CKE L CQILE EL HI AID 808
Cdd:PLN03206 700 G A CA IG E QP I KGL V DP K AMAR LA V G EAL T NLV WA K VTA L S DVK A SGNWM Y AAKL D GEGA D M Y DA AVA L RDAMI EL GV AID 779
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 809 GGKDSLSMAA KV GGE TI K S PG T LVIS T Y AP CPD VRLK VTPDLK GPGA G skt S LL WIN L EN - SA RLGGSALAQAY A Q Q G K D 887
Cdd:PLN03206 780 GGKDSLSMAA QA GGE VV K A PG N LVIS A Y VT CPD ITKT VTPDLK LGDD G --- V LL HVD L GK g KR RLGGSALAQAY D Q I G D D 856
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 888 T P N L TRSDV L G KAF AV TQ S L LGDG LI Q AGHD V SDGGL L V CV LEMA IG G LS G LR VDL SEP laklknfdksvekl NRPELAV 967
Cdd:PLN03206 857 C P D L DDVAY L K KAF EA TQ D L IAKR LI S AGHD I SDGGL V V TL LEMA FA G NC G IN VDL PSS -------------- GHSAFET 922
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 968 LFAEE C G W V V EV LDTD L ER V RSTYEK AGV PNYYL G - VT EG fgld SRVVL K NGKSEL L DQPLRV L YKK WE R TS YE LEKLQ A 1046
Cdd:PLN03206 923 LFAEE L G L V L EV SRKN L DA V MEKLAA AGV TAEVI G q VT AS ---- PLIEV K VDGATC L SEKTAS L RDM WE E TS FQ LEKLQ R 998
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1047 NPE C AEA E YNS L EY R Q AP QYR --- G P QNVQAEL t LKRS S A P v R VA VL REEG V N SE REM M A CLLR A N FE VH DVTMSDLL Q G 1123
Cdd:PLN03206 999 LES C VAQ E KEG L KS R K AP TWK lsf T P AFTDKKI - MNAT S K P - K VA II REEG S N GD REM A A AFYA A G FE PW DVTMSDLL N G 1076
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1124 TA S VSQY RG LI F P GGFSYAD T L G SAKGWA AN I LH N PR LL P QF EA F KR R Q D V FSLG I CNGCQLM T L I G F V GSAKSE -- V GA 1201
Cdd:PLN03206 1077 RI S LDDF RG IV F V GGFSYAD V L D SAKGWA GS I RF N EP LL Q QF QE F YN R P D T FSLG V CNGCQLM A L L G W V PGPQVG gg L GA 1156
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1202 DP D VA --- LL HN K S Q RFECR WAT V K I PSNRS IML GS M KDLV LG C W V AHGEGR FA F R DE KLISHLQSEQ L VTLQ Y V DD V G K 1278
Cdd:PLN03206 1157 GG D PS qpr FV HN E S G RFECR FTS V T I EDSPA IML KG M EGST LG V W A AHGEGR AY F P DE SVLDEVLKSN L APVR Y C DD D G E 1236
1290 1300 1310 1320 1330 1340 1350
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17137292 1279 PTE L YP L NPNGSP Q GIA G LCS S DGRHLA L MPHPERC SS M Y Q W P YV P SSFE V S P t QSE SPW QI MF N NA YN WC 1349
Cdd:PLN03206 1237 PTE Q YP F NPNGSP L GIA A LCS P DGRHLA M MPHPERC FL M W Q F P WY P KEWG V D P - AGP SPW LK MF Q NA RE WC 1306
FGAM_synt
TIGR01735 phosphoribosylformylglycinamidine synthase, single chain form; This model represents a ...
11-1348
0e+00
phosphoribosylformylglycinamidine synthase, single chain form; This model represents a single-molecule form of phosphoribosylformylglycinamidine synthase, also called FGAM synthase, an enzyme of purine de novo biosynthesis. This form is found mostly in eukaryotes and Proteobacteria. In Bacillus subtilis PurL (FGAM synthase II) and PurQ (FGAM synthase I), homologous to different parts of this model, perform the equivalent function; the unrelated small protein PurS is also required and may be a third subunit. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 188163 [Multi-domain]
Cd Length: 1310
Bit Score: 1481.57
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 11 A H S AAEE E SV L RR L REEDGAVVS V RM E R CY HLEY sa QAEHSLALD E L L V -- W L VKQP L SKG QS lsrq P ALQS tgssql LL 88
Cdd:TIGR01735 7 A L S GFRL E KL L QK L QTKVPELTG V YA E F CY FVGW -- ESALTADEE E K L Q ll L L AGSV L EPP QS ---- P LGRG ------ LL 74
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 89 E I GPR FNFST P Y S TNCVN I FQ N L G YSE V R R M E TST RY LVTFGEGSKAPEA A RFVP LL G DRMT QCLYTE E NTPKAS F DEQL 168
Cdd:TIGR01735 75 E V GPR LGTIS P W S SKATS I AR N C G LAK V D R I E RGR RY YLSGAHPLSEEQE A QAAA LL H DRMT ESVLPH E IEAFEL F SVPE 154
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 169 P E rqa N WHFVP VL EE GR A ALE RI NQELGLA FNDYDL DY YHDL F a K EL G RNP TT VEL FDC AQ S NSEH S RH WF F RGRMV IDG 248
Cdd:TIGR01735 155 P L --- N LTTID VL GG GR L ALE KA NQELGLA LDEDEI DY LTKR F - Q EL Q RNP SD VEL MMF AQ A NSEH C RH KI F NADWI IDG 230
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 249 VE Q P KSL IR MI MD T QAHTNP N NTIKFS DNSS AMV G FDHQTIV P SSVVA P GAVRL Q SVQSDLIFTA ETHN M PTA V APF S GA 328
Cdd:TIGR01735 231 KK Q D KSL FQ MI KS T HEANPE N TVSAYK DNSS VIE G HKVGRLR P DPPTR P EYRQH Q EDLVHILMKV ETHN H PTA I APF P GA 310
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 329 T TG T GG RL RD VQGV GRG GV P I AG TA G Y CV GA L H IPG YK QP Y E P l D F KY P ATF A P PL QVL IEA SN GA SDYG N K FG E P VIS G 408
Cdd:TIGR01735 311 S TG A GG EI RD EGAT GRG AK P K AG LT G F CV SN L N IPG LE QP W E D - P F QK P ERI A S PL DIM IEA PL GA AAFN N E FG R P NLL G 389
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 409 FALSYG L NSAADAS Q RDE Y V KPIM FS GG L G TMP A TMRE K LPPAR G Q LL AKI GGP VYR IG V GGGAASS V e IQ G SGD A E LDF 488
Cdd:TIGR01735 390 YFRTFE L KASLPGG Q VRG Y H KPIM LA GG I G SID A EHIQ K GEIEP G A LL IVL GGP AML IG L GGGAASS M - VS G TNT A D LDF 468
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 489 NA VQRG DA EME NKLNR V VRA C LD LGE Q NPI LA IHD Q GAGG NG N V L K EL VEP G FA GAVI FSKEFQ L G DP TITA LE L W GA E Y 568
Cdd:TIGR01735 469 AS VQRG NP EME RRCQE V IDR C WQ LGE K NPI IS IHD V GAGG LS N A L P EL IHD G GR GAVI DLRAVP L D DP GLSP LE I W CN E S 548
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 569 QE NNAI L CN A DQR E LLEK IC R RERCP ISF VG VV TGDGR V TL LEKPAPKDLE Q ALNA S NRSE v S P F DL E L KYV LG D MPK R T 648
Cdd:TIGR01735 549 QE RYVL L VR A ENL E IFTA IC E RERCP FAV VG TA TGDGR L TL VDDTPVRRNG Q GDAP S HFPN - N P V DL P L EVL LG K MPK M T 627
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 649 YDLK R EQTP L KE L SL P K GL L L D EALERVL S L V AV G SKRFL TNKV DR C VGGL I A QQ Q C VGP L Q A PLAD Y A L T TV S HFSHS G 728
Cdd:TIGR01735 628 RFVQ R KAPM L QP L DI P P GL D L H EALERVL R L P AV A SKRFL ITIG DR S VGGL V A RD Q M VGP W Q T PLAD V A V T AA S FDTYT G 707
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 729 I A TS IG TQ P L K G LLDP A A M AR MC V A EA LS NL VFVKISE L A DVK C S G NWM W AA KL PGE G A RMF DA C K ELCQILEE L H IAI D 808
Cdd:TIGR01735 708 E A MA IG ER P P K A LLDP K A S AR LA V G EA IT NL AAALVGD L S DVK L S A NWM A AA GH PGE D A ALY DA V K AVSELCPA L G IAI P 787
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 809 G GKDSLSM AAKVGG ---- ETIKS PG T LVIS TY AP C PDVR LK VTPDLK GPG ag SKTS LL WIN L - ENSA RLGGSALAQ AYA Q 883
Cdd:TIGR01735 788 V GKDSLSM KTRWQD nget KSVTA PG S LVIS AF AP V PDVR KT VTPDLK HDK -- GDSH LL LVD L g PGKN RLGGSALAQ VFG Q 865
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 884 Q G K D T P N L TRSDV L GKA FAV T Q S L LGD GL IQ A G HD V SDGGL LVCV LEMA IG G LS GL R VDL SEPLAK L knfdksveklnrp 963
Cdd:TIGR01735 866 L G G D C P D L DDPER L KAF FAV M Q G L VAE GL LL A Y HD R SDGGL VTTL LEMA FA G HC GL D VDL DALGDS L ------------- 932
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 964 e L AVLF A EE C G W V VE V LDT DL ER V RSTYEK AG VPNYY LG VTEGF G l DSRVVLKNGKSE LL DQPLRV L YKK WE R TS YE L EK 1043
Cdd:TIGR01735 933 - F AVLF N EE L G A V IQ V AKP DL AA V LELLRA AG LTALI LG IGTPT G - HPMIRISVNGAT LL SEKRSE L RDI WE E TS FQ L QR 1010
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1044 L QA NPECAE A E YNS L EY R QA P QYR ----- GPQNVQ A ELTLKRSSA P v R VA V LRE E GVN SE REM M A CLL RA N FE VH DV T MS 1118
Cdd:TIGR01735 1011 L RD NPECAE E E FEG L RD R DG P GLK lpltf DVNEDI A APFINKGVK P - K VA I LRE Q GVN GD REM A A AFD RA G FE AW DV H MS 1089
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1119 DLL Q G TASVSQY RGL IFP GGFSY A D T LG SA KGWA AN IL H NPRL LP QF E AF KR R Q D V FSLG I CNGCQ LMT - L IGFVG saks 1197
Cdd:TIGR01735 1090 DLL A G RVHLDEF RGL AAC GGFSY G D V LG AG KGWA KS IL F NPRL RD QF Q AF FK R P D T FSLG V CNGCQ MLS n L LEWIP ---- 1165
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1198 ev G ADPDVALLH N K S Q RFE C R W A T V KIPSNR SIML GS M KDLV L GCW VAHGEG RF AF RDEK L ISHLQSEQ L VT L Q Y V DD V G 1277
Cdd:TIGR01735 1166 -- G TENWPHFVR N N S E RFE A R V A S V RVGESP SIML RG M AGSR L PVA VAHGEG YA AF SSPE L QAQADASG L AA L R Y I DD D G 1243
1290 1300 1310 1320 1330 1340 1350
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17137292 1278 K PTE L YPLNPNGSP Q GIAG LC S S DGR HLAL MPHPER CSSMY Q WPYV P SSF evspt QSES PW QIM F N NA Y NW 1348
Cdd:TIGR01735 1244 N PTE A YPLNPNGSP G GIAG IT S C DGR VTIM MPHPER VFRAW Q NSWR P EDW ----- DEDT PW LRL F R NA R NW 1309
PRK05297
PRK05297 phosphoribosylformylglycinamidine synthase; Provisional
1-1349
0e+00
phosphoribosylformylglycinamidine synthase; Provisional
Pssm-ID: 235394 [Multi-domain]
Cd Length: 1290
Bit Score: 1389.14
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1 M V ILR yy DVQ A H SA AEEESV L R RL REEDGA V V S VRM E RCYH leys A QAEHS L ALD E L -- L VW L vkqplskgqs L SRQ PA L 78
Cdd:PRK05297 1 M L ILR -- GSP A L SA FRLQKL L A RL QAAVLP V T S IYA E YVHF ---- A DLSAP L SAE E Q ak L ER L ---------- L TYG PA E 64
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 79 QSTGSSQL L le IG PR FNFST P Y S TNCVN I FQ N L G YSEV RR M E TSTR Y L V TFG eg SK A PEA A RFVP LL G DRMT QCLYTEEN 158
Cdd:PRK05297 65 HEPAGRLF L -- VT PR PGTIS P W S SKATD I AH N C G LAGI RR I E RGIA Y Y V EAA -- LS A EQR A ALAA LL H DRMT ESVFADLD 140
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 159 TPK A S F DEQL P ERQA nwh F V P VL EE GRAALE RI N Q ELGLA FNDYDL DY YHDL F A K e LGRNPT T VEL FDC AQ S NSEH S RH W 238
Cdd:PRK05297 141 DAE A L F SHHE P KPLT --- S V D VL GG GRAALE AA N V ELGLA LAEDEI DY LVEA F T K - LGRNPT D VEL MMF AQ A NSEH C RH K 216
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 239 F F RGRMV IDG V EQPKSL IR MI MD T QAH t NP NNTIK - FS DN SSA M V G FDHQTIV P SS vv AP G AVRLQSVQSDLIFTA ETHN 317
Cdd:PRK05297 217 I F NADWT IDG E EQPKSL FK MI KN T HET - NP DGVLS a YK DN AAV M E G SKVGRFF P DP -- DT G RYGYHQEPAHILMKV ETHN 293
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 318 M PTA VA PF S GA T TG T GG RL RD VQGV GRG GV P I AG TA G YC V GA L H IPG YK QP Y E P l D FKY P ATF A PP L QVL IE ASN G ASDY 397
Cdd:PRK05297 294 H PTA IS PF P GA A TG S GG EI RD EGAT GRG SK P K AG LT G FS V SN L R IPG FE QP W E E - D YGK P ERI A SA L DIM IE GPL G GAAF 372
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 398 G N K FG E P VIS G FALSYGLNSAADASQRDE Y V KPIM FS GG L G TMP A TMRE K LPPAR G QL L AKI GGP VY RIG V GGGAASS VE 477
Cdd:PRK05297 373 N N E FG R P NLL G YFRTFEQKVNSHNEEVRG Y H KPIM LA GG I G NIR A DHVQ K GEIPV G AK L IVL GGP AM RIG L GGGAASS MA 452
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 478 i Q G SGDAE LDF NA VQRG DA EME NKLNR V VRA C LD LG EQ NPIL A IHD Q GAGG NG N VLK ELV EP G FA G AVIFSKEFQLGD P T 557
Cdd:PRK05297 453 - S G QSSED LDF AS VQRG NP EME RRCQE V IDR C WQ LG DD NPIL S IHD V GAGG LS N AFP ELV ND G GR G GRFDLRKIPNDE P G 531
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 558 ITA LE L W GA E Y QE NNAILCNADQR EL L E K IC R RERCP ISF VG VV T GDGRV TL lekpapkdl E QALNASN rsevs P F DL E L 637
Cdd:PRK05297 532 MSP LE I W CN E S QE RYVLAIAPEDL EL F E A IC E RERCP FAV VG EA T EERHL TL --------- E DSHFDNK ----- P V DL P L 597
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 638 KYV LG DM PK RTY D L K REQTPLKE L SL p K G LL L D EA L ERVL S L VA V G SK R FL TNKV DR C V G GL I A QQ Q C VGP L Q A P L AD Y A 717
Cdd:PRK05297 598 DVL LG KP PK MHR D V K TVKAKGPA L DY - S G ID L A EA V ERVL R L PT V A SK S FL ITIG DR S V T GL V A RD Q M VGP W Q V P V AD C A 676
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 718 L T TV S HFSHS G I A TSI G TQPLKG LLD P AA M ARM C V A EAL S N LVFVK I SE L ADV K C S G NWM W AA KL PGE G AR MF DA C K --- 794
Cdd:PRK05297 677 V T AA S YDGYA G E A MAM G ERTPVA LLD A AA S ARM A V G EAL T N IAAAP I GD L KRI K L S A NWM A AA GH PGE D AR LY DA V K avg 756
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 795 - ELC Q ile E L H I A I DG GKDSLSM AA K V -- GGE -- TIK SP GT L V IS TY AP CP DVR LKV TP D L KGPGA gsk T S LL W I N L ENS 869
Cdd:PRK05297 757 m ELC P --- A L G I T I PV GKDSLSM KT K W qe GGE dk EVT SP LS L I IS AF AP VE DVR KTL TP Q L RTDKD --- T A LL L I D L GRG 830
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 870 A - RLGGSALAQ A Y A Q Q G KDT P NLTRSDV L GKA F AVT Q S L LGD GL IQ A G HD V SDGGLL VCVL EMA IG G LS GL RV DL S epla 948
Cdd:PRK05297 831 K n RLGGSALAQ V Y N Q L G DKA P DVDDAED L KGF F NAI Q A L VAE GL LL A Y HD R SDGGLL TTLA EMA FA G HC GL DI DL D ---- 906
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 949 klknfdksve K L NRPE LA V LF A EE C G W V VE V LDT D LER V RSTYEKA G VPN -- YYL G - VTE gfgl DS R V V LKNGKSELLDQ 1025
Cdd:PRK05297 907 ---------- A L GDDA LA A LF N EE L G A V IQ V RAA D RDA V EAILAEH G LSD cv HVI G k PNA ---- GD R I V ITRNGKTVFSE 972
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1026 PLRV L YKK W ER TSY ELEK L QA NPECA EA E YNSLEYRQA P ------ QYRGPQNVQ A EL t LKRSSA P v R VA V LRE E GVNS ER 1099
Cdd:PRK05297 973 SRTE L RRW W SE TSY QMQR L RD NPECA DQ E FDAILDQAD P glnvkl TFDPNEDIA A PF - IATGAR P - K VA I LRE Q GVNS HV 1050
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1100 EM M A CLL RA N F EVH DV T MSDLL Q G TASVSQYR GL IFP GGFSY A D T LG SAK GWA AN IL H NPRL LP QFEAF KR R Q D V F S LG I 1179
Cdd:PRK05297 1051 EM A A AFD RA G F DAI DV H MSDLL A G RVTLEDFK GL VAC GGFSY G D V LG AGE GWA KS IL F NPRL RD QFEAF FA R P D T F A LG V 1130
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1180 CNGCQ L M tligfvg S AKS E V -- GA DPDVALLH N K S QR FE C R WAT V KIPSNR SI M L GS M KDLV L GCW VAHGEGR FA F R D EK 1257
Cdd:PRK05297 1131 CNGCQ M M ------- S NLK E I ip GA EHWPRFVR N R S EQ FE A R FSL V EVQESP SI F L QG M AGSR L PIA VAHGEGR AE F P D AH 1203
1290 1300 1310 1320 1330 1340 1350 1360
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1258 L i SH L QSEQ LV T L Q YVD DV G KP TE L YP L NPNGSP Q GI A GL CSS DGR HLAL MPHPER CSSMY Q WPYV P SSF evspt QSE SP 1337
Cdd:PRK05297 1204 L - AA L EAKG LV A L R YVD NH G QV TE T YP A NPNGSP N GI T GL TTA DGR VTIM MPHPER VFRTV Q NSWH P EEW ----- GED SP 1277
1370
....*....|..
gi 17137292 1338 W QI MF N NA YN W C 1349
Cdd:PRK05297 1278 W MR MF R NA RK W V 1289
PurL1
COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain [Nucleotide transport and ...
181-1047
0e+00
Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain [Nucleotide transport and metabolism]; Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439816 [Multi-domain]
Cd Length: 747
Bit Score: 634.40
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 181 LE E GR A ALE RI N Q ELGLA FN D YDL DY YH dlfa KE LGRNPT T VEL FDCA Q SN SEH SRHWFFRGRM vidgveqp KSL I rmim 260
Cdd:COG0046 6 LE G GR E ALE EA N R ELGLA LS D DEY DY IV ---- EI LGRNPT D VEL GMFS Q MW SEH CSYKSSNALL -------- KSL P ---- 69
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 261 dtqah T NPNNTI - KFS DN SSAMVGF D HQTI V pssvvapgavrlqsvqsdli F TA E T HN M P T A VA P FS GA T TG T GG RL RD V 339
Cdd:COG0046 70 ----- T EGPRVL s GPG DN AGVVDIG D GLAV V -------------------- F KV E S HN H P S A IE P YQ GA A TG V GG II RD I 124
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 340 qg V G R G GV PIAG TAGYCV G A L HI P GYK qpyepldfkypatfap P LQV LI EASN G AS DYGN K FG E P VIS G FALSY glnsaa 419
Cdd:COG0046 125 -- F G M G AR PIAG LDSLRF G N L DQ P PAS ---------------- P RYI LI GVVA G IA DYGN C FG V P TVG G EVRFD ------ 180
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 420 dasqr DE Y V - K P IMFS GG L G TMP A -- TMRE K L P PA r G QLLAKI GGP VY R I G V GG GAAS S V E I qg SG D A ELD FN AVQ R GD A 496
Cdd:COG0046 181 ----- ES Y E g N P LVNA GG V G IIR A dh IFKA K A P GV - G NKVVYV GGP TG R D G I GG ATFA S E E L -- GE D S ELD RP AVQ V GD P 252
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 497 E ME NK L nrv VR A C L D LG EQNP I LA I H D Q GAGG NGNVLK E LVEP G FA GA V I FSKEFQ L GD P TITAL E L W GA E Y QE NNAILC 576
Cdd:COG0046 253 F ME KR L --- IE A I L E LG DTGL I VG I Q D M GAGG LSSASS E MAAK G GL GA E I DLDKVP L RE P GMSPY E I W LS E S QE RMLLVV 329
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 577 NADQR E LL E K I CR R E R C P ISFV G V VT G DGR VTLL --- E KP A pkdleqalnasnrsevspf DL E L KYVL G DM PK RTYDL KR 653
Cdd:COG0046 330 KPEKL E EF E A I FE R W R L P AAVI G E VT D DGR LVVT dhg E TV A ------------------- DL P L DFLA G GA PK YHRPA KR 390
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 654 E q TP L KE L S LP KGLL L D EAL E R V LS LVA V G SK RF L TNKV DR C VGG LIAQQQ cvgplqa PL AD Y A LTT V SH f SHS G I A T S I 733
Cdd:COG0046 391 P - AY L EP L D LP EPID L E EAL L R L LS SPN V A SK EW L YRQY DR E VGG NTVRDP ------- GV AD A A VVR V DG - TYK G L A M S T 461
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 734 G TQ P LKG LLDP A A M ARM C VAEA LS NL VF V KISE LA d VKCSG NW MWAA K l P G E G A RMFD A C K --- EL C Q ile E L H I AIDG G 810
Cdd:COG0046 462 G EN P RYA LLDP Y A G ARM A VAEA AR NL AA V GAEP LA - ITDCL NW GNPE K - P E E M A QLVE A V K gla DA C R --- A L G I PVPS G 536
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 811 KD SL SMAA K V G GET I ks P G T L VI STYAPCP DVR LK VTPDLK GP G agsk TS L LW I N l E NSAR LGGS AL AQ AYA Q Q G KDT P N 890
Cdd:COG0046 537 NV SL YNET K D G KVA I -- P P T P VI GAVGLVD DVR KT VTPDLK KE G ---- DL L YL I G - E TKNE LGGS EY AQ VLG Q L G GEP P D 609
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 891 L t RSDVLGKA F AVT Q S L LGD GLI Q A G HDVSDGGL L V CVL EMA IG G LS G LRV DL SEP laklknfdksvek LNRPEL A V LF A 970
Cdd:COG0046 610 V - DLEAEKAL F EAV Q E L IRE GLI L A A HDVSDGGL A V ALA EMA FA G GL G ADI DL DAL ------------- GDLRPD A A LF S 675
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 17137292 971 E EC G - W VV E V LDT D L E R V RSTYEK AG V P NYYL G VTE G fgl D S R V V LKN G KSE LL DQP L RV L YKK WE R T sye L EK L QA N 1047
Cdd:COG0046 676 E SQ G r A VV Q V APE D A E A V EALLAE AG L P AHVI G TVT G --- D D R L V IRR G GET LL SLS L AE L RDA WE E T --- L PR L RD N 747
GATase_5
pfam13507 CobB/CobQ-like glutamine amidotransferase domain; This family captures members that are not ...
1085-1349
8.48e-134
CobB/CobQ-like glutamine amidotransferase domain; This family captures members that are not found in pfam00310, pfam07685 and pfam13230.
Pssm-ID: 463904 [Multi-domain]
Cd Length: 260
Bit Score: 411.12
E-value: 8.48e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1085 V RVA V LRE E G V N S E R EM M A CLL RA N F EVH DV T MSDLL Q G TA S VSQYR GL IF PGGFSY A D T LGS A KGWAA N IL H NP R L LPQ 1164
Cdd:pfam13507 2 P RVA I LRE P G T N G E Y EM A A AFE RA G F DAV DV H MSDLL S G RV S LDDFQ GL AA PGGFSY G D V LGS G KGWAA S IL F NP K L RDA 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1165 FEAF KR R Q D V FSLGICNGCQL MTLI G FVGSAKSEV g A DPDVA L LH N K S Q RFE C RW AT VKI P - SNR S IM L GS M K dl VL G CW 1243
Cdd:pfam13507 82 FEAF FN R P D T FSLGICNGCQL LSKL G LIPGGEGDL - A ERWPT L TR N D S G RFE S RW VN VKI S e KSP S VF L RG M D -- GS G LP 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1244 VAHGEGRF A FR D E KLISH L QSEQL V T L Q YVD DV G K PTE L YP L NPNGSP Q GIAG L CS S DGR H L A LMPHPER CSSMY QWP YV 1323
Cdd:pfam13507 159 VAHGEGRF V FR S E EVLAR L EANGQ V A L R YVD NA G N PTE E YP F NPNGSP L GIAG I CS P DGR V L G LMPHPER VFRPW QWP HW 238
250 260
....*....|....*....|....*.
gi 17137292 1324 P SSFE vspt QSE SPW QIM F N NA YN W C 1349
Cdd:pfam13507 239 P PGEW ---- EEV SPW LRL F R NA RK W V 260
PHA03366
PHA03366 FGAM-synthase; Provisional
117-1352
7.98e-118
FGAM-synthase; Provisional
Pssm-ID: 223058 [Multi-domain]
Cd Length: 1304
Bit Score: 399.78
E-value: 7.98e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 117 R RM ETS t RY L VT F GEGSKA PE AA R F V ---------- P L LGDRMTQC --- L Y T EENTPKASFDEQL pe R QANWHFVPV L -- 181
Cdd:PHA03366 1 M RM PFQ - LT L LF F ADADLS PE EE R L V allldrpgpl T L ISGPLQSE hll L V T VRGSASDPRPRRQ -- R REELALILA L ls 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 182 - EEGRAA L ERINQEL G LA f NDYDLD Y YH DL ------ F AK EL GR ----- NPTT V E -------- L F DCA QS NS EH srhwff R 241
Cdd:PHA03366 78 p LLEYTP L TTESRGK G GS - RTLSFS Y GP DL nrrptt F SR EL VA llqtl GLRE V L rielgrhl T F KLL QS PL EH ------ H 150
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 242 GRMVIDGVEQ P K SL I R MIMDT Q AHTN -------- P NN T IKF SD NSSAMV gfdh QTIVPSSVVAPG A VR -- L Q SVQSDLIF 311
Cdd:PHA03366 151 MDQLLEALLL P D SL L R PYIEG Q ESRG lvtaplap P AL T APL SD PLDKVC ---- NGVMGDLPLGGD A LP va I Q ASSPLPGY 226
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 312 T AETHNM -- PT AVAPF S ------------------ G ATTGT G GR L RDV --- QGVGR GG V P I A GTA G Y cv GALHIP G y KQ P 368
Cdd:PHA03366 227 T VAYYLS lt PT CTSVR S nyltrgahsvetgflhth G SIQTM G PQ L TGL lfq PSLLP GG L P R A SAL G W -- YVTTPS G - GG P 303
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 369 YE PL DFKYP A TF app L QVLIEAS N GA sdygnkf G E PV IS GF als YGLNSAAD A SQRDEYVKPIM F SGG L G T MPATMREKL 448
Cdd:PHA03366 304 LS PL APRQI A ET --- L EAQARSL N CS ------- G V PV VG GF --- LRTIPTTL A LISPLPNNMLT F TSL L S T ISTIALDTA 370
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 449 PPAR GQ LLAKI G -- G P VY rigvg G GAASSVEIQG SG dae L DF N AVQRGDAEMENK L NR -- VVRACLD LG EQ n PI L AI hdq 524
Cdd:PHA03366 371 RYRP GQ YIVAL G sf E P SS ----- G PDTPPYLYRD SG --- L EA N KILQALKLFYSL L PG pc ISGSSRP LG PA - SV L EH --- 438
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 525 gaggngnv L KE L VE PG fa G AVI F - S K efq L GDPTITA L ELW - GAEYQE N NA I L ------ CNADQ ---------------- 580
Cdd:PHA03366 439 -------- L LA L CP PG -- G LLL F l S A --- L PEDVVSG L KPF s ASNRET N EE I V kqyfln VYCSV vflvikntheggegvt 505
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 581 - REL L EKI CR RER CP ISFV G VVTGDGRVTLL ekpapkdle QA L NASNRS E VSPFDLELKYV L G dm P K R TYDLKREQTPLK 659
Cdd:PHA03366 506 p LDA L KRA CR LAG CP VHIL G RTVPLPGIHFV --------- ND L GNPVYG E LRDDQFKPTFP L Q -- P S R PLSPVSATSEDT 574
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 660 EL S LPKG ------ LL L DEA L ERV LS LVA VGSK RFLTNKV DRC VG G LI AQQ QC VGPL QA P LA DY ALTTV S H - FSH ------ 726
Cdd:PHA03366 575 RP S PQDE sidwal FN L NST L LQI LS HPT VGSK EYIVRHI DRC GN G RV AQQ PG VGPL DL P VS DY SIVVH S S v KTR raietp 654
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 727 ---------------------------------- S G IATSI G T Q PL K GL LDP AAM A RMCVA EAL S NL VFVKISE L A D VKC 772
Cdd:PHA03366 655 sstedltyqeadelinspltwfdpddesvlhpav P G TCSAL G E Q GY K VQ LDP ILG A KYAIV EAL T NL MLAPVAN L E D ITI 734
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 773 SGNWM W A akl P GEG A ----- R MFD ACKE L C qil E EL HIAI dggkd SLSM A AKVGGETIKSPG ----- T L V ISTY AP C P DV 842
Cdd:PHA03366 735 TLSVT W P --- P TDQ A asely R ALA ACKE F C --- R EL GVNF ----- TFTS A SSSPRQDQPPQP gplfn T I V FTAS AP V P SS 803
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 843 RLKV TPDLK G PG agsk TS L LWINLENSAR L G GS ALA Q AYAQQGKDT P NLT r SDV L GKA F AVT Q S L LGD GL IQA GHDVSDG 922
Cdd:PHA03366 804 TPRL TPDLK K PG ---- SA L VHLSISPEYT L A GS VFE Q IFGLKSGTL P DIS - PSY L KNL F RAV Q H L ISE GL VVS GHDVSDG 878
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 923 GL LV C VL EMA IG G LS G LRVDLSEPL aklknfdksveklnr PE L AV LF A E EC G W V V EV LDTD L ER V RSTYEKAGVPN Y YL G 1002
Cdd:PHA03366 879 GL IA C LA EMA LA G GR G VTITVPAGE --------------- DP L QF LF S E TP G V V I EV PPSH L SA V LTRLRSRNIIC Y PI G 943
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1003 VTEGF G LDSRVVLKNGKSE L LDQP L RV L YKK W ERT S Y E LEK L QA n P ECA E AEYNSLE Y r QAPQYR g PQNVQAE LT L ---- 1078
Cdd:PHA03366 944 TVGPS G PSNTFSVSHNGTV L FRES L SS L RST W RSF S D E QFE L LR - P DLT E ESMYRKD Y - GNNEVD - LGPLEEG LT T splr 1020
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1079 -- KRSSAPV RVAVL REE G VNSEREMM A CLLR A N F EVHD V TMSD L LQ GT a SVSQYR GL IFP G GFSYA D TLGS A KGWA A NI L 1156
Cdd:PHA03366 1021 ly TCPDKRH RVAVL LLP G CPGPHALL A AFTN A G F DPYP V SIEE L KD GT - FLDEFS GL VIG G SSGAE D SYTG A RAAV A AL L 1099
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1157 H NP RLLPQFEA F KR R Q D V FSLG ICN - GCQ LMTLIGF VGS - A K S E V GADP ----- DVA L LH N K S QRF E C RW ATVK IP - SNR 1228
Cdd:PHA03366 1100 S NP AVRDALLR F LN R P D T FSLG CGE l GCQ ILFALKA VGS t A P S P V PGTE teeqw PIT L EP N A S GLY E S RW LNFY IP e TTK 1179
1290 1300 1310 1320 1330 1340 1350 1360
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1229 S IM L GSMKDL VL G CW V ahg E G R --- F AFRDEKLISH L QSEQLVTLQY ---- VD D v G K P TEL YP L NP N G - S P qg I AGLCS S 1300
Cdd:PHA03366 1180 S VA L RPLRGS VL P CW A --- Q G T hlg F RYPNDGMEYI L RNSGQIAATF hgad VD P - G N P ARH YP R NP T G n S N -- V AGLCS A 1253
1370 1380 1390 1400 1410
....*....|....*....|....*....|....*....|....*....|..
gi 17137292 1301 DGRHLAL MPH P ERCSSMY QW PY VP SSFE vs P TQS e SPW QI MF NNAYN WC V K S 1352
Cdd:PHA03366 1254 DGRHLAL LFD P SLSFHPW QW QH VP PENG -- P LKV - SPW KL MF QDLHL WC L K H 1302
PurL_repeat1
cd02203 PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. ...
223-612
1.61e-115
PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP, phosphate, and glutamate in the fourth step of the purine biosynthetic pathway. In eukaryotes and Gram-negative bacteria, FGAR-AT is encoded by the purL gene as a multidomain protein with a molecular mass of about 140 kDa. In Gram-positive bacteria and archaea FGAR-AT is a complex of three proteins: PurS, PurL, and PurQ. PurL itself contains two tandem N- and C-terminal domains (four domains altogether). The N-terminal domains bind ATP and are related to the ATP-binding domains of HypE, ThiL, SelD and PurM.
Pssm-ID: 100034 [Multi-domain]
Cd Length: 313
Bit Score: 364.10
E-value: 1.61e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 223 EL FDC AQ SN SEH S RH WF F rgrmvidgveqp KSL IR MI MD tqahtnpnntikfsdnssamvgfdhqtivpssvvapgavrl 302
Cdd:cd02203 1 EL GMF AQ MW SEH C RH KS F ------------ KSL LK MI WA ----------------------------------------- 27
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 303 qsvqsd LI F TA ETHN M P T A VA PF S GA T TG T GG RL RD VQGV G rg GV PIA GTA G YCV G A L H IPGY K qpyepldfky P ATFAP 382
Cdd:cd02203 28 ------ VV F KV ETHN H P S A IE PF G GA A TG V GG II RD ILSM G -- AR PIA LLD G LRF G D L D IPGY E ---------- P KGKLS 89
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 383 P LQV L IEASN G A SDYGN KF G E P VIS G FALSYG lnsaadasqr DE Y VK P IMFS G GL G TM P ATMRE K - LP P AR G Q L LAKI GG 461
Cdd:cd02203 90 P RRI L DGVVA G I SDYGN CI G I P TVG G EVRFDP ---------- SY Y GN P LVNV G CV G IV P KDHIV K s KA P GP G D L VVLV GG 159
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 462 PVY R I G V GG GAA SS V E I q GSGDA ELD FN AVQ R GD AE ME N KL NRVVRACL dlg E QNP I LA I H D Q GAGG NGNVLK E LVEP G F 541
Cdd:cd02203 160 RTG R D G I GG ATF SS K E L - SENSS ELD RP AVQ V GD PF ME K KL QEAILEAR --- E TGL I VG I Q D L GAGG LSSAVS E MAAK G G 235
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17137292 542 A GA V I FSKEFQ L GD P TITAL E L W GA E Y QE NNAILCNADQR E LLEK IC RR E RCPISFV G V VT G DGR VT L LE K 612
Cdd:cd02203 236 L GA E I DLDKVP L RE P GMSPW E I W IS E S QE RMLLVVPPEDL E EFLA IC KK E DLEAAVI G E VT D DGR LR L YY K 306
GATase1_FGAR_AT
cd01740 Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ...
1087-1346
4.65e-97
Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase (FGAR-AT). FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP, Pi, and glutamate in the fourth step of the purine biosynthetic pathway. FGAR-AT is a glutamine amidotransferase. Glutamine amidotransferase activity catalyses the transfer of ammonia from the amide side chain of glutamine to an acceptor substrate. FGAR-AT belongs to the triad family of amidotransferases having a conserved Cys-His-Glu catalytic triad in the glutaminase active site
Pssm-ID: 153211 [Multi-domain]
Cd Length: 238
Bit Score: 310.70
E-value: 4.65e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1087 VAVLR EE G V N SE R E M MACLLR A N FE VH DV TMS DLL Q G TASVSQ Y R G LIF PGGFSY A D T L GSAKGW AA nilh N P R L LPQFE 1166
Cdd:cd01740 1 VAVLR FP G S N CD R D M AYAFEL A G FE AE DV WHN DLL A G RKDLDD Y D G VVL PGGFSY G D Y L RAGAIA AA ---- S P L L MEEVK 76
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1167 A F KR R q DVFS LGICNG C Q LMTLI G FVGS aksevgadpdv AL LH NK SQR F E CRW A ---- T VKIPS N R S IML - G S M KDL VL G 1241
Cdd:cd01740 77 E F AE R - GGLV LGICNG F Q ILVEL G LLPG ----------- AL IR NK GLK F I CRW Q nrfv T LRVEN N D S PFT k G Y M EGE VL R 144
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1242 CW VAHGEGRF AFR DE K L ISHLQSE Q LV tl QYVDD V G KP TE L YP L NPNGS PQ GIAG L C SS DGR H L AL MPHPER CSSMY QW P 1321
Cdd:cd01740 145 IP VAHGEGRF YAD DE T L AELEENG Q IA -- QYVDD D G NV TE R YP A NPNGS LD GIAG I C NE DGR V L GM MPHPER AVEPW QW E 222
250 260
....*....|....*....|....*
gi 17137292 1322 YVPSS fevsptqse S PWQIM F N NA Y 1346
Cdd:cd01740 223 RLLGG --------- S DGLKL F R NA V 238
PurL2
COG0047 Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain ...
1086-1350
3.09e-79
Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain [Nucleotide transport and metabolism]; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439817 [Multi-domain]
Cd Length: 236
Bit Score: 260.76
E-value: 3.09e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1086 R VA V L REE G V N SE R E M M A CLL RA NF E VH DV TM SDL lqg TASVSQYR GL IF PGGFSY A D T L GSAKGW A AN ilhnp RLLPQF 1165
Cdd:COG0047 2 K VA I L VFP G S N CD R D M A A AFE RA GA E AE DV WH SDL --- RTDLDDFD GL VL PGGFSY G D Y L RAGAIA A FS ----- PIMDAV 73
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1166 EA F K RR q DVFS LGICNG C Q LM T LI G FVG saksev G AD P dv AL LH N K S Q RF E CRW ATVKIPS N R S IMLGS M - KDL V LGCWV 1244
Cdd:COG0047 74 RE F A RR - GGLV LGICNG F Q IL T EL G LLP ------ G IW P -- AL TR N R S L RF I CRW VYLRVEN N D S PFTSG M e AGE V IPIPI 144
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1245 AHGEGR FAF r DE KLISH L QSEQL V TLQ YVD DV G KP T el YP L NPNGS PQG IAG LCSS DG RH L AL MPHPER CSSMYQW P yvp 1324
Cdd:COG0047 145 AHGEGR YVA - DE ETLAE L EANGQ V AFR YVD AD G NV T -- YP A NPNGS LNN IAG ITNE DG NV L GM MPHPER AVEPLLG P --- 218
250 260
....*....|....*....|....*.
gi 17137292 1325 ssfevspt QSESPWQIM F NN A YNWCV 1350
Cdd:COG0047 219 -------- GESTDGLRI F RS A VKYFG 236
PurL_repeat2
cd02204 PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. ...
715-1004
1.61e-76
PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP, phosphate, and glutamate in the fourth step of the purine biosynthetic pathway. In eukaryotes and Gram-negative bacteria, FGAR-AT is encoded by the purL gene as a multidomain protein with a molecular mass of about 140 kDa. In Gram-positive bacteria and archaea FGAR-AT is a complex of three proteins: PurS, PurL, and PurQ. PurL itself contains two tandem N- and C-terminal domains (four domains altogether). The N-terminal domains bind ATP and are related to the ATP-binding domains of HypE, ThiL, SelD and PurM.
Pssm-ID: 100035 [Multi-domain]
Cd Length: 264
Bit Score: 254.38
E-value: 1.61e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 715 D Y A LTTVSHFSHS G I A T S I G TQ P LKG LLDP A A M A RMC VAEA LS NLV F V KISE LA d VKCSG N WMWAA K LP GE GARMFD A CK 794
Cdd:cd02204 1 D A A VLRIPGETDK G L A M S T G EN P RYS LLDP Y A G A ALA VAEA VR NLV A V GADP LA - ITDCL N FGNPE K PE GE MGQLVE A VL 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 795 E L CQILEE L HIAID GGKDSL SMAAKV gget IKS P G TLVI STYAPCP DVR LK VT P D L K GP G agsk TS L LW I NLENS a R LGG 874
Cdd:cd02204 80 G L GDACRA L GTPVI GGKDSL YNETEG ---- VAI P P TLVI GAVGVVD DVR KI VT L D F K KE G ---- DL L YL I GETKD - E LGG 150
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 875 S AL A Q AY AQQ G KDT P N L TRSDVLGKA F AVT Q S L LGD GL IQAG HDVSDGGL L V CVL EMA IG G LS G LR VDLS EPL A klknfd 954
Cdd:cd02204 151 S EY A L AY HGL G GGA P P L VDLEREKAL F DAV Q E L IKE GL VLSA HDVSDGGL A V ALA EMA FA G GL G AE VDLS KDD A ------ 224
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 17137292 955 ksveklnrp E LAV LF A E EC G W V VEVLDTDL E R V RS t Y E K AGVP NYYL G VT 1004
Cdd:cd02204 225 --------- E DEL LF S E SL G R V LVEVKPEN E E V FE - A E E AGVP ATVI G TV 264
FGAM_synth_II
TIGR01736 phosphoribosylformylglycinamidine synthase II; Phosphoribosylformylglycinamidine synthase is a ...
209-1009
7.86e-51
phosphoribosylformylglycinamidine synthase II; Phosphoribosylformylglycinamidine synthase is a single, long polypeptide in most Proteobacteria and eukarotes. Three proteins are required in Bacillus subtilis and many other species. This is the longest of the three and is designated PurL, phosphoribosylformylglycinamidine synthase II, or FGAM synthase II. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 273781 [Multi-domain]
Cd Length: 715
Bit Score: 192.90
E-value: 7.86e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 209 D L FAKE LGR N P TTV EL FDCAQSN SEH ----- S RHWFFR ---- G RM VI D G VEQPKSLIR m I M D TQ A htnpnntikfsdnss 279
Cdd:TIGR01736 7 E L IREI LGR E P NDT EL AMFSAMW SEH csyks S KKLLKQ fptk G PN VI Q G PGEDAGVVD - I G D GY A --------------- 70
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 280 amvgfdhqtivpssvvapgavrlqsvqsd LI F TA E T HN M P T A VA P FS GA T TG T GG R LRD V qg VGR G GV PIA GTAGYCV G A 359
Cdd:TIGR01736 71 ----------------------------- VV F KM E S HN H P S A IE P YN GA A TG V GG I LRD I -- LSM G AR PIA LLDSLRF G P 119
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 360 L HI P gy K QP Y epldfkypatfapplq VLIEASN G A SDYGN KF G E P VIS G --- F AL SY GL N saadasqrdeyvk P IMFSGG 436
Cdd:TIGR01736 120 L DD P -- K NR Y ---------------- LFEGVVA G I SDYGN RI G V P TVG G eve F DE SY NG N ------------- P LVNVMC 168
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 437 L G TMP atm REKLPPAR ---- G QL L AKI GG PVY R I G V GG GAAS S V E IQGSGDA E l D FN AVQ R GD AEM E NK L nrv VR A C L DL 512
Cdd:TIGR01736 169 V G LVR --- KDDIVTGK akgp G NK L VLV GG KTG R D G I GG ATFA S E E LSEEAEE E - D RP AVQ V GD PFT E KL L --- IE A T L EA 241
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 513 GEQNPILA I H D Q GA G G NGNVLK E LVEP G FA GA V I FSKEFQ L GD P TI T AL E LWGA E Y QE NNAILCNADQR E LLEK I CRRER 592
Cdd:TIGR01736 242 VDTGLVKG I K D L GA A G LTSASS E MAAK G GL GA E I YLDKVP L RE P GM T PY E IMLS E S QE RMLLVVAPEDV E EVLE I FEKYE 321
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 593 C P I S FV G V VT GD GR VT L LE K papkdleqalnasnrsevspfdlel KY V LG D M P KR ------ T Y DLK - REQTPLK E LSL P K 665
Cdd:TIGR01736 322 L P A S VI G E VT DE GR IR L YY K ------------------------- GE V VA D L P IE lladap E Y ERP s EPPKYPE E EKE P E 376
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 666 GLL - L DE A LER VLS LVAVG SK RFLTNKV D RC V GG liaqqqcv GPLQA P LA D Y A LTTVSHFSHS G I A TSIGTQ P LKGL LDP 744
Cdd:TIGR01736 377 PPA d L ED A FLK VLS SPNIA SK EWVYRQY D HE V QT -------- RTVVK P GE D A A VLRIKETGKL G L A LTADCN P RYVY LDP 448
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 745 A A M A RMC VAEA LS NL VF V KISE LA D V K C -- S GN ------- W MWAAKLP G egar MF DAC K elcqile E L HIAID GG KD SL S 815
Cdd:TIGR01736 449 Y A G A AGA VAEA YR NL AA V GAEP LA A V D C ln F GN perpevy W QFVEAVK G ---- LG DAC R ------- A L GTPVV GG NV SL Y 517
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 816 maakvg G ET IKS P -- G T LV I STYAPCP DV R lk VTPDLKGPGA G SKTS L LW inl E NSAR LGGS ALAQAYAQQGKDTPNLTR 893
Cdd:TIGR01736 518 ------ N ET NGV P ia P T PT I GMVGLVE DV E -- KLLTSNFKKE G DAIY L IG --- E TKDE LGGS EYLRVIHGIVSGQVPAVD 586
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 894 SDVLGKAFAVTQSLLGD GL IQ A G HDVS D GGL L V CVL EMA IGGLS G LR VD LS E P laklknfdksvek LNRPELAV LF A E EC 973
Cdd:TIGR01736 587 LEEEKELADAVREAIRA GL VS A A HDVS R GGL A V ALA EMA AASGI G AE VD ID E I ------------- ASARPDEL LF S E SN 653
810 820 830
....*....|....*....|....*....|....*..
gi 17137292 974 G - WV V E V LD tdl E RVRSTYEKA GVP NYYL G V T E G FG L 1009
Cdd:TIGR01736 654 G r AI V A V PE --- E KAEEAVKSK GVP AKVI G K T G G DR L 687
PRK01175
PRK01175 phosphoribosylformylglycinamidine synthase I; Provisional
1084-1322
6.65e-48
phosphoribosylformylglycinamidine synthase I; Provisional
Pssm-ID: 234913 [Multi-domain]
Cd Length: 261
Bit Score: 172.25
E-value: 6.65e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1084 PV RVAVLR E EG V N S E R E MMACLL R ANF E VHD V TMS DL LQGTA SVS Q Y RG L IF PGGFS YA D TLGSAKGW AA NIL hn PR L LP 1163
Cdd:PRK01175 3 SI RVAVLR M EG T N C E D E TVKAFR R LGV E PEY V HIN DL AAERK SVS D Y DC L VI PGGFS AG D YIRAGAIF AA RLK -- AV L RK 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1164 QF E A F KR r QDVFSL GICNG C Q LMTLI G FV g SAKS E VGAD P DV AL LH N K S Q RFECR WATV K IPSNRS I MLGSM K DL V LGCW 1243
Cdd:PRK01175 81 DI E E F ID - EGYPII GICNG F Q VLVEL G LL - PGFD E IAEK P EM AL TV N E S N RFECR PTYL K KENRKC I FTKLL K KD V FQVP 158
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 17137292 1244 VAH G EGR FA F RD E KLISH L QSEQLVTLQ YVD DV G KPTE l YP L NPNGS PQG IAG LCSSD G RHLA LMPHPER CSSM YQ W PY 1322
Cdd:PRK01175 159 VAH A EGR VV F SE E EILER L IENDQIVFR YVD EN G NYAG - YP W NPNGS IYN IAG ITNEK G NVIG LMPHPER AFYG YQ H PY 236
PurL
cd02193 Formylglycinamide ribonucleotide amidotransferase (FGAR-AT) catalyzes the ATP-dependent ...
311-599
6.88e-44
Formylglycinamide ribonucleotide amidotransferase (FGAR-AT) catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP, phosphate, and glutamate in the fourth step of the purine biosynthetic pathway. In eukaryotes and Gram-negative bacteria, FGAR-AT is encoded by the purL gene as a multidomain protein with a molecular mass of about 140 kDa. In Gram-positive bacteria and archaea FGAR-AT is a complex of three proteins: PurS, PurL, and PurQ. PurL itself contains two tandem N- and C-terminal domains (four domains altogether). The N-terminal domains bind ATP and are related to the ATP-binding domains of HypE, ThiL, SelD and PurM.
Pssm-ID: 100029 [Multi-domain]
Cd Length: 272
Bit Score: 160.93
E-value: 6.88e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 311 FTA E T HN M P T A VA P FS GA T TG T GG RL RD VQGV G RGGV PIA GT A GYCVG A L H IP gykqpyepldfkypatfap PLQV L IE A 390
Cdd:cd02193 5 MKI E E HN H P A A ID P AA GA A TG V GG AI RD IAAT G IDAK PIA LS A NWMAS A G H PG ------------------- EDAI L YD A 65
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 391 SN G ASDYG N KF G E P VIS G - FAL S YGLNSAADAS QR DEYVK P IMFSGGL G TMPATMREKLPPAR - G QL L AK IGG PVYRI G V 468
Cdd:cd02193 66 VK G VAELC N QL G L P IPV G k DRM S MKTRWQEGNE QR EMTHP P SLVISAF G RVRDDRHTLPQLST e G NA L LL IGG GKGHN G L 145
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 469 GG G A AS SV EIQ gsg DAE L DFNAV Q RG D AEM E NKLNRVVR A CLDL G eqn PI LA I HD Q GAGG NGNV L K ELV EP G FA G AVIFS 548
Cdd:cd02193 146 GG T A LA SV ALS --- YRQ L GDKSA Q VR D PAQ E KGFYEAMQ A LVAA G --- KL LA W HD R GAGG LLVA L A ELV FA G HC G VQVDL 219
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 17137292 549 KEFQLGD P TITA LE LWGA E Y QE NNA I LCN A DQ R ELL E KICRRERCPISFV G 599
Cdd:cd02193 220 AALGDDE P DMEP LE IALF E S QE RGV I QVR A ED R DAV E EAQYGLADCVHVL G 270
PRK01213
PRK01213 phosphoribosylformylglycinamidine synthase subunit PurL;
309-1037
5.73e-41
phosphoribosylformylglycinamidine synthase subunit PurL;
Pssm-ID: 234921 [Multi-domain]
Cd Length: 724
Bit Score: 162.58
E-value: 5.73e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 309 LI F TA E T HN M P T AV A P FS GA T TG T GG R LRD VQGV G - R ggv PIA gtagy CVGA L H ipgykqpyepldfkypat F APP ---- 383
Cdd:PRK01213 83 VV F KI E S HN H P S AV E P YQ GA A TG V GG I LRD IFSM G a R --- PIA ----- LLDS L R ------------------ F GEL dhpk 136
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 384 - LQV L IEASN G ASD YGN KF G E P VIS G --- F AL SY GL N saadasqrdeyvk P IMFSGGL G TMPA tmr EKLPP A RGQ lla KI 459
Cdd:PRK01213 137 t RYL L EGVVA G IGG YGN CI G V P TVG G evy F DE SY NG N ------------- P LVNAMCV G LVRH --- DDIVL A KAS --- GV 197
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 460 G G PV Y ------- R I G V GG GAAS S V E I qg S GDA E LDFN AVQ R GD AE ME NK L nrv VR ACL D L GEQNPILA I H D Q GA G G NGNV 532
Cdd:PRK01213 198 G N PV V yvgaktg R D G I GG ASFA S A E L -- S EES E EKRP AVQ V GD PF ME KL L --- IE ACL E L IKTGLVVG I Q D M GA A G LTCS 272
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 533 LK E LVEP G FA G AVIFSKEFQ L GDPTI T AL E LWGA E Y QE NNAILCNADQR E LLEK I CRRERCPISFV G V VT G DGR VTLL -- 610
Cdd:PRK01213 273 SS E MAAK G GL G IELDLDKVP L REEGM T PY E IMLS E S QE RMLLVVKPGKE E EVLA I FEKWDLDAAVI G E VT D DGR LRVY hh 352
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 611 - E KP A pkdleqalnasnrsevspf D LELKYVLGDM P kr T YD LKREQTPLKELSLPKGLL L D EAL ERV LS LVAVG SK RFLT 689
Cdd:PRK01213 353 g E VV A ------------------- D VPAEALADEA P -- V YD RPYKEPAYLDELQADPED L K EAL LKL LS SPNIA SK EWVY 411
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 690 NKV D RC V GG liaqqqcv GPLQA P LA D Y A LTTV s HFSHS G I A TSIGTQ P LKGL LDP AAM A RMC VAEA LS NL VF V KISE LA D 769
Cdd:PRK01213 412 EQY D HE V QT -------- NTVVK P GG D A A VLRI - RGGGK G L A LTTDCN P RYVY LDP YEG A KLA VAEA AR NL AA V GATP LA I 482
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 770 VK C -- S GN ----- W MW AAKLPGE G ar MF DAC KE L cqileel HIAID GG KD SL --- S maakv GG ET I K s P g T L VI STYAPC 839
Cdd:PRK01213 483 TD C ln F GN pekpe V MW QFVEAVR G -- LA DAC RA L ------- GTPVV GG NV SL yne T ----- GG TA I Y - P - T P VI GMVGLI 546
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 840 P DV RLKV T PDL K GP G agskt S L LWINL E NSAR LGGS ALAQAYAQQGKDT P NLTRSDVLGKAFAVTQSLLGD GL IQAG HDV 919
Cdd:PRK01213 547 D DV SKRT T SGF K KE G ----- D L IYLLG E TKDE LGGS EYLKVIHGHVGGR P PKVDLEAEKRLQELVREAIRE GL VTSA HDV 621
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 920 S D GGL L V CVL EMAI G G LS G LR VDLS EP L aklknfdksvekln RP E l A V LF A E EC G - W VV E V LDTDL E RVRSTY E K AGVP N 998
Cdd:PRK01213 622 S E GGL A V ALA EMAI A G GL G AE VDLS DG L -------------- RP D - A L LF S E SQ G r Y VV S V PPENE E AFEALA E A AGVP A 686
730 740 750
....*....|....*....|....*....|....*....
gi 17137292 999 YYL GV TE G fgld SRVVL K NGKS E L L DQ plrv L YKK WE RT 1037
Cdd:PRK01213 687 TRI GV VG G ---- DALKV K GNDT E S L EE ---- L REA WE GA 717
FGAM_synth_I
TIGR01737 phosphoribosylformylglycinamidine synthase I; In some species, ...
1085-1315
1.52e-39
phosphoribosylformylglycinamidine synthase I; In some species, phosphoribosylformylglycinamidine synthase is composed of a single polypeptide chain. This model describes the PurQ protein of Bacillus subtilis (where PurL, PurQ, and PurS are required for phosphoribosylformylglycinamidine synthase activity) and functionally equivalent proteins from other bacteria and archaea. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 273782 [Multi-domain]
Cd Length: 227
Bit Score: 146.75
E-value: 1.52e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1085 VR VAV L R EE G V N SE R EMMAC L LRANFEVHD V TMS D llqgt A S VSQ Y R G LIF PGGFSY A D T L g S A KGW AA nilhnpr LL P Q 1164
Cdd:TIGR01737 1 MK VAV I R FP G T N CD R DTVYA L RLLGVDAEI V WYE D ----- G S LPD Y D G VVL PGGFSY G D Y L - R A GAI AA ------- AS P I 67
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1165 FEAFKRRQD -- V FS LGICNG C Q LMT ligfvgsaks E V G AD P D v ALL H N K S Q RF E CRW ATVKIPSNRS I ML - GSM K DL V LG 1241
Cdd:TIGR01737 68 MQEVREFAE kg V PV LGICNG F Q ILV ---------- E A G LL P G - ALL P N D S L RF I CRW VYLRVENADT I FT k NYK K GE V IR 136
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 17137292 1242 CWV AHGEGR FAFR DE K L IS h L Q S EQL V TLQ Y V D DV G KPT E ly PL NPNGS PQG IAG LCSSD G RH L AL MPHPER C S 1315
Cdd:TIGR01737 137 IPI AHGEGR YYAD DE T L AR - L E S NDQ V VFR Y C D ED G DVA E -- EA NPNGS VGN IAG IVNER G NV L GM MPHPER A S 207
PRK03619
PRK03619 phosphoribosylformylglycinamidine synthase subunit PurQ;
1085-1315
4.60e-31
phosphoribosylformylglycinamidine synthase subunit PurQ;
Pssm-ID: 235140 [Multi-domain]
Cd Length: 219
Bit Score: 122.15
E-value: 4.60e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1085 VR VAV LREE G V N SE R E M M - A CLLRANF E VHD V T msdll QGTASVSQYRGLIF PGGFSY A D T L GS ak G WA A nilhnp RLL P 1163
Cdd:PRK03619 1 MK VAV IVFP G S N CD R D M A r A LRDLLGA E PEY V W ----- HKETDLDGVDAVVL PGGFSY G D Y L RC -- G AI A ------ AFS P 67
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1164 QFE A F K R -- RQDVFS LGICNG C Q LM T LI G FV - G saksevgadpdv AL LH N K S QR F E CR WATVKIPS N RSIMLGSM - K DL V 1239
Cdd:PRK03619 68 IMK A V K E fa EKGKPV LGICNG F Q IL T EA G LL p G ------------ AL TR N A S LK F I CR DVHLRVEN N DTPFTSGY e K GE V 135
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 17137292 1240 LGCWV AHGEG RF a FR DE KLISH L QSEQL V TLQ Y V D D vgkptelypl NPNGS PQG IAG LCSSD G RH L AL MPHPER CS 1315
Cdd:PRK03619 136 IRIPI AHGEG NY - YA DE ETLKR L EGNGQ V VFR Y C D E ---------- NPNGS VND IAG IVNEK G NV L GM MPHPER AV 200
AIRS_C
pfam02769 AIR synthase related protein, C-terminal domain; This family includes Hydrogen expression ...
453-609
7.69e-28
AIR synthase related protein, C-terminal domain; This family includes Hydrogen expression/formation protein HypE, AIR synthases EC:6.3.3.1, FGAM synthase EC:6.3.5.3 and selenide, water dikinase EC:2.7.9.3. The function of the C-terminal domain of AIR synthase is unclear, but the cleft formed between N and C domains is postulated as a sulphate binding site.
Pssm-ID: 460684 [Multi-domain]
Cd Length: 152
Bit Score: 110.51
E-value: 7.69e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 453 G QL L AKI G G pvyr I G VG G GAA S SVEIQGSGDAE ldf N AVQ R GD AEM E NK L NR V VRACLD LG eq NPIL A I HD QGA GG NGNV 532
Cdd:pfam02769 3 G DV L ILL G S ---- S G LH G AGL S LSRKGLEDSGL --- A AVQ L GD PLL E PT L IY V KLLLAA LG -- GLVK A M HD ITG GG LAGA 73
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 17137292 533 L K E LVEPGFA GA V I FSKEFQLGDPTITA LE LWGA E Y Q ENNAILCNADQR E LLEK I CRR E RCPISFV G V VT GD GR V T L 609
Cdd:pfam02769 74 L A E MAPASGV GA E I DLDKVPIFEELMLP LE MLLS E N Q GRGLVVVAPEEA E AVLA I LEK E GLEAAVI G E VT AG GR L T V 150
FGAR-AT_N
pfam18076 Formylglycinamide ribonucleotide amidotransferase N-terminal; This is the N-terminal domain ...
37-164
1.49e-26
Formylglycinamide ribonucleotide amidotransferase N-terminal; This is the N-terminal domain found in Formylglycinamide ribonucleotide amidotransferase (FGAR-AT), also known as Phosphoribosylformylglycinamidine synthase (EC:6.3.5.3), PurL and formylglycinamidine ribonucleotide (FGAM) synthase. This enzyme catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide and glutamine to formylglycinamidine ribonucleotide, ADP, Pi, and glutamate in the fourth step of the purine biosynthetic pathway.
Pssm-ID: 465635 [Multi-domain]
Cd Length: 115
Bit Score: 105.25
E-value: 1.49e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 37 E RCYHL E YS A -- Q A EHSLA L DE LL vwlvkqplskgqsl SRQ P A L QSTGSSQL LL EIG PR FNFST P Y S TNCVN I FQ N L G YS 114
Cdd:pfam18076 1 E YVHFV E LE A pl S A AERAR L EQ LL -------------- TYG P P L EEPEPEGE LL LVT PR LGTIS P W S SKATD I AH N C G LD 66
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 17137292 115 E VRR M E TSTR Y LV T FGEG S K A p E A A RFVP LL G DRMT QCLY T EENTPK A S F 164
Cdd:pfam18076 67 A VRR I E RGIA Y YL T GKPL S A A - E L A ALAA LL H DRMT ESVL T DLEDAA A L F 115
PurL
cd02193 Formylglycinamide ribonucleotide amidotransferase (FGAR-AT) catalyzes the ATP-dependent ...
728-1002
4.42e-19
Formylglycinamide ribonucleotide amidotransferase (FGAR-AT) catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP, phosphate, and glutamate in the fourth step of the purine biosynthetic pathway. In eukaryotes and Gram-negative bacteria, FGAR-AT is encoded by the purL gene as a multidomain protein with a molecular mass of about 140 kDa. In Gram-positive bacteria and archaea FGAR-AT is a complex of three proteins: PurS, PurL, and PurQ. PurL itself contains two tandem N- and C-terminal domains (four domains altogether). The N-terminal domains bind ATP and are related to the ATP-binding domains of HypE, ThiL, SelD and PurM.
Pssm-ID: 100029 [Multi-domain]
Cd Length: 272
Bit Score: 88.89
E-value: 4.42e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 728 G I A TS I GTQPLKGLL DPAA M A RMC V AE A LSNLVFVK I s ELADVKC S G NWM WA A KL PGE G A RMF DA C K ELCQILEE L HIA I 807
Cdd:cd02193 2 G E A MK I EEHNHPAAI DPAA G A ATG V GG A IRDIAATG I - DAKPIAL S A NWM AS A GH PGE D A ILY DA V K GVAELCNQ L GLP I 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 808 DG GKD SL SM -- AAKV G G E TIK -- S P GT LVIS TYAPCP D V R L k VT P D L KGP G A gskt S LL W I NL - ENSAR LGG S ALA Q --- 879
Cdd:cd02193 81 PV GKD RM SM kt RWQE G N E QRE mt H P PS LVIS AFGRVR D D R H - TL P Q L STE G N ---- A LL L I GG g KGHNG LGG T ALA S val 155
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 880 A Y A Q Q G KDTPNLTRSDVLGKAFAVT Q S L LGD G LIQ A G HD VSD GGLLV CVL E MAIG G LS G LR VDL SEPLAK lknfdksv E K 959
Cdd:cd02193 156 S Y R Q L G DKSAQVRDPAQEKGFYEAM Q A L VAA G KLL A W HD RGA GGLLV ALA E LVFA G HC G VQ VDL AALGDD -------- E P 227
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 17137292 960 LNR P ELAV LF AEECGW V VE V LDT D LER V RSTYEKAGVPNYY LG 1002
Cdd:cd02193 228 DME P LEIA LF ESQERG V IQ V RAE D RDA V EEAQYGLADCVHV LG 270
PRK14090
PRK14090 phosphoribosylformylglycinamidine synthase subunit PurL;
207-614
5.95e-16
phosphoribosylformylglycinamidine synthase subunit PurL;
Pssm-ID: 184499 [Multi-domain]
Cd Length: 601
Bit Score: 82.98
E-value: 5.95e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 207 Y HDLFAKE LGR N PT T VEL FDCAQSN SEH S rhwffrgrmvid G VEQP K SL IR MI mdtqahtnpnntikfsdnss AMV GF DH 286
Cdd:PRK14090 3 Y LNILEEK LGR E PT F VEL QAFSVMW SEH C ------------ G YSHT K KY IR RL -------------------- PKT GF EG 50
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 287 QT ivpssvvap G A V R L QSVQ S d LI F TA E T HN M P T A VA P FS GA T TG T GG RL RDV qg VGR G GV P I A gtagy CVGA LH I pgyk 366
Cdd:PRK14090 51 NA --------- G V V N L DDYY S - IA F KI E S HN H P S A IE P YN GA A TG V GG II RDV -- LAM G AR P T A ----- IFDS LH M ---- 109
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 367 qpyepldfkypatf APPLQVL IE asn G AS DYGN KF G E P VIS G --- FALS Y GL N SAAD asqrdeyvkp IMFS G glgtmp AT 443
Cdd:PRK14090 110 -------------- SRIIDGI IE --- G IA DYGN SI G V P TVG G elr ISSL Y AH N PLVN ---------- VLAA G ------ VV 156
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 444 MREK L PPAR ---- GQ LLAKI GG PVY R I G VG G GAAS S VEIQ G SGDAE L dfn AV Q R GD AEM E NK L nrv VR A C L DLG E QNPIL 519
Cdd:PRK14090 157 RNDM L VDSK asrp GQ VIVIF GG ATG R D G IH G ASFA S EDLT G EKATK L --- SI Q V GD PFA E KM L --- IE A F L EMV E EGLVE 230
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 520 AIH D Q GAGG NGNVLK ELV EP G FA GA VIFSKEFQ L GD P TITAL E LWGA E Y QE NN A ILCNADQRELLEK I CRRERCPISF V G 599
Cdd:PRK14090 231 GAQ D L GAGG VLSATS ELV AK G GL GA IVHLDRVP L RE P DMEPW E ILIS E S QE RM A VVTSPEKASRILE I AKKHLLFGDI V A 310
410 420
....*....|....*....|..
gi 17137292 600 V V TG D GRV ------- TLL E K P A 614
Cdd:PRK14090 311 E V ID D PIY rvmyrdd LVM E V P V 332
AIRS_C
pfam02769 AIR synthase related protein, C-terminal domain; This family includes Hydrogen expression ...
866-1013
6.10e-13
AIR synthase related protein, C-terminal domain; This family includes Hydrogen expression/formation protein HypE, AIR synthases EC:6.3.3.1, FGAM synthase EC:6.3.5.3 and selenide, water dikinase EC:2.7.9.3. The function of the C-terminal domain of AIR synthase is unclear, but the cleft formed between N and C domains is postulated as a sulphate binding site.
Pssm-ID: 460684 [Multi-domain]
Cd Length: 152
Bit Score: 67.76
E-value: 6.10e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 866 L EN S ARL G GSALAQAYAQQGKDTPNLTRS D V L -- GKAFA V TQS L LGD - GL IQ A G HD VSD GGL LVCVL EMA IGGLS G LRV D 942
Cdd:pfam02769 9 L GS S GLH G AGLSLSRKGLEDSGLAAVQLG D P L le PTLIY V KLL L AAL g GL VK A M HD ITG GGL AGALA EMA PASGV G AEI D 88
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17137292 943 L SEP laklknfd KSV E K L NR P e L AV L FA E EC G WVVE V LDT - DL E R V RSTY EK A G VPNYYL G - VT E G FG L DSR V 1013
Cdd:pfam02769 89 L DKV -------- PIF E E L ML P - L EM L LS E NQ G RGLV V VAP e EA E A V LAIL EK E G LEAAVI G e VT A G GR L TVI V 152
FGAR-AT_linker
pfam18072 Formylglycinamide ribonucleotide amidotransferase linker domain; This is the linker domain ...
188-237
9.06e-12
Formylglycinamide ribonucleotide amidotransferase linker domain; This is the linker domain found in Formylglycinamide ribonucleotide amidotransferase (FGAR-AT), also known as Phosphoribosylformylglycinamidine synthase (EC:6.3.5.3), PurL and formylglycinamidine ribonucleotide (FGAM) synthase. This enzyme catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP, Pi, and glutamate in the fourth step of the purine biosynthetic pathway. The structure analysis of Salmonella typhimurium FGAR-AT reveals that this linker domain is made up of a long hydrophilic belt with an extended conformation.
Pssm-ID: 465632 [Multi-domain]
Cd Length: 50
Bit Score: 60.94
E-value: 9.06e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 17137292 188 LE RI N QE LGLA FN D YDL DY YHDL FA K e LGRNPT T VEL FDC AQ SN SEH S RH 237
Cdd:pfam18072 1 LE EA N RY LGLA LS D DEI DY LVEY FA G - LGRNPT D VEL GMF AQ MW SEH C RH 49
GATase1
cd01653 Type 1 glutamine amidotransferase (GATase1)-like domain; Type 1 glutamine amidotransferase ...
1087-1191
2.10e-07
Type 1 glutamine amidotransferase (GATase1)-like domain; Type 1 glutamine amidotransferase (GATase1)-like domain. This group includes proteins similar to Class I glutamine amidotransferases, the intracellular PH1704 from Pyrococcus horikoshii, the C-terminal of the large catalase: Escherichia coli HP-II, Sinorhizobium meliloti Rm1021 ThuA. and, the A4 beta-galactosidase middle domain. The majority of proteins in this group have a reactive Cys found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow. For Class I glutamine amidotransferases proteins which transfer ammonia from the amide side chain of glutamine to an acceptor substrate, this Cys forms a Cys-His-Glu catalytic triad in the active site. Glutamine amidotransferases activity can be found in a range of biosynthetic enzymes included in this cd: glutamine amidotransferase, formylglycinamide ribonucleotide, GMP synthetase, anthranilate synthase component II, glutamine-dependent carbamoyl phosphate synthase, cytidine triphosphate synthetase, gamma-glutamyl hydrolase, imidazole glycerol phosphate synthase and, cobyric acid synthase. For Pyrococcus horikoshii PH1704, the Cys of the nucleophile elbow together with a different His and, a Glu from an adjacent monomer form a catalytic triad different from the typical GATase1 triad. The E. coli HP-II C-terminal domain, S. meliloti Rm1021 ThuA and the A4 beta-galactosidase middle domain lack the catalytic triad typical GATaseI domains. GATase1-like domains can occur either as single polypeptides, as in Class I glutamine amidotransferases, or as domains in a much larger multifunctional synthase protein, such as CPSase.
Pssm-ID: 153210 [Multi-domain]
Cd Length: 115
Bit Score: 50.67
E-value: 2.10e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1087 VAVL REE G VNSE -- REMMAC L LR A NF EV HD V TMS - DLLQGTASVSQ Y R GLI F PGG FSYA D T L gsakgwaani LHNPR LL P 1163
Cdd:cd01653 1 VAVL LFP G FEEL el ASPLDA L RE A GA EV DV V SPD g GPVESDVDLDD Y D GLI L PGG PGTP D D L ---------- ARDEA LL A 70
90 100
....*....|....*....|....*...
gi 17137292 1164 QFEAF k RRQDVFS LGIC N G C QL M t LI G F 1191
Cdd:cd01653 71 LLREA - AAAGKPI LGIC L G A QL L - VL G V 96
GAT_1
cd03128 Type 1 glutamine amidotransferase (GATase1)-like domain; Type 1 glutamine amidotransferase ...
1087-1186
1.23e-06
Type 1 glutamine amidotransferase (GATase1)-like domain; Type 1 glutamine amidotransferase (GATase1)-like domain. This group contains proteins similar to Class I glutamine amidotransferases, the intracellular PH1704 from Pyrococcus horikoshii, the C-terminal of the large catalase: Escherichia coli HP-II, Sinorhizobium meliloti Rm1021 ThuA, the A4 beta-galactosidase middle domain and peptidase E. The majority of proteins in this group have a reactive Cys found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow. For Class I glutamine amidotransferases proteins which transfer ammonia from the amide side chain of glutamine to an acceptor substrate, this Cys forms a Cys-His-Glu catalytic triad in the active site. Glutamine amidotransferases activity can be found in a range of biosynthetic enzymes included in this cd: glutamine amidotransferase, formylglycinamide ribonucleotide, GMP synthetase, anthranilate synthase component II, glutamine-dependent carbamoyl phosphate synthase (CPSase), cytidine triphosphate synthetase, gamma-glutamyl hydrolase, imidazole glycerol phosphate synthase and, cobyric acid synthase. For Pyrococcus horikoshii PH1704, the Cys of the nucleophile elbow together with a different His and, a Glu from an adjacent monomer form a catalytic triad different from the typical GATase1 triad. Peptidase E is believed to be a serine peptidase having a Ser-His-Glu catalytic triad which differs from the Cys-His-Glu catalytic triad of typical GATase1 domains, by having a Ser in place of the reactive Cys at the nucleophile elbow. The E. coli HP-II C-terminal domain, S. meliloti Rm1021 ThuA and the A4 beta-galactosidase middle domain lack the catalytic triad typical GATaseI domains. GATase1-like domains can occur either as single polypeptides, as in Class I glutamine amidotransferases, or as domains in a much larger multifunctional synthase protein, such as CPSase. Peptidase E has a circular permutation in the common core of a typical GTAse1 domain.
Pssm-ID: 153222 [Multi-domain]
Cd Length: 92
Bit Score: 47.97
E-value: 1.23e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 1087 VAVL REE G VNSE -- REMMAC L LR A NF EV HD V TMS - DLLQGTASVSQ Y R GLI F PGG FSYA D T L gsakgwaani LHNPR LL P 1163
Cdd:cd03128 1 VAVL LFG G SEEL el ASPLDA L RE A GA EV DV V SPD g GPVESDVDLDD Y D GLI L PGG PGTP D D L ---------- AWDEA LL A 70
90 100
....*....|....*....|...
gi 17137292 1164 QFEAF k RRQDVFS LGIC N G C QL M 1186
Cdd:cd03128 71 LLREA - AAAGKPV LGIC L G A QL L 92
PurM-like
cd00396 AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen ...
728-1002
2.58e-04
AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain of AIR synthase forms the dimer interface of the protein, and is suggested as a putative ATP binding domain.
Pssm-ID: 100027 [Multi-domain]
Cd Length: 222
Bit Score: 43.92
E-value: 2.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 728 GI A T S IGTQPLKGLLD P A A MA R MC V AE A LSNLVFVKISEL A dvk CSGNWMWAAK L PGEGARMF - D ACK E L C qil EE L HIA 806
Cdd:cd00396 1 SL A M S TDGINPPLAIN P W A GG R LA V GG A VNDIAAMGARPI A --- LLASLSLSNG L EVDILEDV v D GVA E A C --- NQ L GVP 74
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 807 I dggkdslsmaak VGG E T IK SPGT L vistyap CPD vrlkvt PD L KGPGA G sktsllwi NL E NSARLGG S A laqay A QQ G K 886
Cdd:cd00396 75 I ------------ VGG H T SV SPGT M ------- GHK ------ LS L AVFAI G -------- VV E KDRVIDS S G ----- A RP G D 116
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 887 dtp N L TRSD V L gkafa VTQS L LGD G LIQ A G HD VS DGGLL VCVL E M A IGGLS G LRV DL s E PLAKLKNFD ks VEKLNRP E L A 966
Cdd:cd00396 117 --- V L ILTG V D ----- AVLE L VAA G DVH A M HD IT DGGLL GTLP E L A QASGV G AEI DL - E AIPLDEVVR -- WLCVEHI E E A 185
250 260 270
....*....|....*....|....*....|....*.
gi 17137292 967 V LF AEEC G WVVE V LDTDLER V RSTYEKA G VPNYYL G 1002
Cdd:cd00396 186 L LF NSSG G LLIA V PAEEADA V LLLLNGN G IDAAVI G 221
AIRS
pfam00586 AIR synthase related protein, N-terminal domain; This family includes Hydrogen expression ...
309-408
1.23e-03
AIR synthase related protein, N-terminal domain; This family includes Hydrogen expression/formation protein HypE, AIR synthases EC:6.3.3.1, FGAM synthase EC:6.3.5.3 and selenide, water dikinase EC:2.7.9.3. The N-terminal domain of AIR synthase forms the dimer interface of the protein, and is suggested as a putative ATP binding domain.
Pssm-ID: 459859 [Multi-domain]
Cd Length: 104
Bit Score: 39.74
E-value: 1.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137292 309 LIF T AET H NM P TA V A P -- F S GA T t GTG G R L R D V qg VGR G GV P I A GTAGYCVGALH ipgykqpyepldfkypatfa PPLQ V 386
Cdd:pfam00586 5 VAV T TDG H GT P SL V D P yh F P GA K - AVA G N L S D I -- AAM G AR P L A FLDSLALPGGP -------------------- EVEW V 61
90 100
....*....|....*....|..
gi 17137292 387 L I E ASN G ASDYGNKF G E P VIS G 408
Cdd:pfam00586 62 L E E IVE G IAEACREA G V P LVG G 83
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
