|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
270-772 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 710.18 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 270 KTRNMRSLNPEDMDQLISISGMVIRSSNVIPEMREAFFSCNICSFSTTVEVDRGRINQPTLCTN--CNTNHCFRLIHNRS 347
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQSGRETEPTVCPPreCQSPTPFSLNHERS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 348 EFTDKQLVKLQESPDDMAAGQTPHNVLLYAHNDLVDKVQPGDRVTVTGIYRATPLKTGGLSSSVKSVYKTHVDVVHFRKV 427
Cdd:smart00350 81 TFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVPYGFKLNTVKGLPVFATYIEANHVRKL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 428 DNKRLYEDEEGKDHIFPPERVELLQLLAKKPDIYDRLARAIAPSIYENDDIKKGILLQLFGGTKKKhaTLGRQNFRSEIH 507
Cdd:smart00350 161 DYKRSFEDSSFSVQSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKN--LPDGMKIRGDIN 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 508 LLLCGDPGTSKSQMLQYVFNLVPRSQYTSGRGSSAVGLTAYVTKDPETRQLVLQTGALVLADNGVCCIDEFDKMNDSTRS 587
Cdd:smart00350 239 ILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDDSDRT 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 588 VLHEVMEQQTLSIAKAGIICQLNARTSILAAANPAESQWNKRKNIIDNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASH 667
Cdd:smart00350 319 AIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRELAKH 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 668 LVSLyYVTRHEEEDT----MFDMSVLRDYIAYAREHLSPTLSDEAQQRLIQAYVDMRKVGA---GRGQISAYPRQLESLI 740
Cdd:smart00350 399 VVDL-HRYSHPEEDEafepPLSQEKLRKYIAYAREKIKPKLSEEAADKLVKAYVDLRKEDSqteSRSSIPITVRQLESII 477
|
490 500 510
....*....|....*....|....*....|..
gi 17137242 741 RLSEAHAKVRLSNQVELLDVEEAWRLHREALK 772
Cdd:smart00350 478 RLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
196-855 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 610.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 196 YLQKLEEI--HTLEEPYLNLNCAHLKTFDQDLYRQLICYPQEVIPGFDMAINEmfFERYPAALLEHQIQVRPFNADKTRN 273
Cdd:COG1241 18 YRDEILELaqEYPEKRSLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEALRE--IDLEPYDVSLGDAHVRITNLPETVP 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 274 MRSLNPEDMDQLISISGMVIRSSNVIPEMREAFFSCNICSFSTTVEVDRGRINQPTLCTNCNTNHCFRLIHNRSEFTDKQ 353
Cdd:COG1241 96 IRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTETYVPQTGEKLQEPHECPGCGRQGPFKLLPEKSEFIDAQ 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 354 LVKLQESPDDMAAGQTPHNVLLYAHNDLVDKVQPGDRVTVTGIYRATPLKTGGLSSSVksvYKTHVDVVHFRKVDnkRLY 433
Cdd:COG1241 176 KIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQRTSGRGKSTI---FDLYLEANSIEVEE--KEF 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 434 EDEEgkdhIFPPERVELLQLlAKKPDIYDRLARAIAPSIYENDDIKKGILLQLFGGTKKKHATLGRqnFRSEIHLLLCGD 513
Cdd:COG1241 251 EEIE----ITEEDEEKIKEL-SKDPDIYEKIIASIAPSIYGYEEIKEAIALQLFGGVPKVLPDGSR--IRGDIHILLVGD 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 514 PGTSKSQMLQYVFNLVPRSQYTSGRGSSAVGLTAYVTKDPE-TRQLVLQTGALVLADNGVCCIDEFDKMNDSTRSVLHEV 592
Cdd:COG1241 324 PGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDDFgTGRWTLEAGALVLADGGLACIDELDKMREEDRSALHEA 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 593 MEQQTLSIAKAGIICQLNARTSILAAANPAESQWNKRKNIIDNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASHLVSLY 672
Cdd:COG1241 404 MEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKPDEERDRELARHILKVH 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 673 Y--------VTRHEEEDT-MFDMSVLRDYIAYAREHLSPTLSDEAQQRLIQAYVDMRKVGAGRGQ-ISAYPRQLESLIRL 742
Cdd:COG1241 484 RagelleqeIEEETEEVKpEIDPDLLRKYIAYARRNVFPVLTEEAKDLIEDFYVDMRKKGEDEDSpVPITARQLEALIRL 563
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 743 SEAHAKVRLSNQVELLDVEEAWRLHREALKQSATDPLSGKIDVGILTTGLSTAARKKRADLVAAIKENLKKKGKvlTVPY 822
Cdd:COG1241 564 AEASARMRLSDTVTEEDAERAIRLVDSCLKDVGVDPETGKFDIDVIETGTSKSQRDKMKLIKDIIKELEEESSG--GAPI 641
|
650 660 670
....*....|....*....|....*....|...
gi 17137242 823 QKLfsdIKEGSQIMITREQFEDALKEVQDEGAI 855
Cdd:COG1241 642 EDV---IEEAEEEGIDREKAEELIEKLKRKGEI 671
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
463-770 |
0e+00 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 596.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 463 RLARAIAPSIYENDDIKKGILLQLFGGTKKKHATlGRQNFRSEIHLLLCGDPGTSKSQMLQYVFNLVPRSQYTSGRGSSA 542
Cdd:cd17755 1 RLARSIAPSIYELEDVKKGILLQLFGGTRKDFTK-TGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 543 VGLTAYVTKDPETRQLVLQTGALVLADNGVCCIDEFDKMNDSTRSVLHEVMEQQTLSIAKAGIICQLNARTSILAAANPA 622
Cdd:cd17755 80 VGLTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 623 ESQWNKRKNIIDNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASHLVSLYYVTRHEE-EDTMFDMSVLRDYIAYAREHLS 701
Cdd:cd17755 160 GSRYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLYLEDTPEHiQDEVLDVEVLTDYISYAREHIH 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 702 PTLSDEAQQRLIQAYVDMRKVGAG-RGQISAYPRQLESLIRLSEAHAKVRLSNQVELLDVEEAWRLHREA 770
Cdd:cd17755 240 PKLSEEAAQELVQAYVDMRKMGSDaRKRITATPRQLESLIRLAEAHAKMRLSNVVEAEDVEEAVRLIREA 309
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
167-855 |
0e+00 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 565.32 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 167 KFKSFIMRFIDPSaeqdeisenidvNQPLYLQKLEEIHTLEEPYLNLNCAHLKTFDQDLYRQLICYPQEVIPGFDMAINE 246
Cdd:NF040949 4 KFKEFIRTFRDSF------------GNEKYKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALKE 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 247 MFFERYPA-ALLEHQIQVRPFNADKTRNMRSLNPEDMDQLISISGMVIRSSNVIPEMREAFFSCNIC--SFSTTVEVDRG 323
Cdd:NF040949 72 IVEEEDPEyAEEVAKFHVRFRNLPRTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCgcEFEWPEEEEES 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 324 --RINQPTLCTNCNTNHCFRLIHNRSEFTDKQLVKLQESPDDMAAGQTPHNVLLYAHNDLVDKVQPGDRVTVTGIYRATP 401
Cdd:NF040949 152 yeIVEPPTVCPVCGKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIKP 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 402 lkTGGLSSSVKSVYKTHVDVVHFrKVDNKRLYEDEegkdhiFPPERVELLQLLAKKPDIYDRLARAIAPSIYENDDIKKG 481
Cdd:NF040949 232 --DSSLKKGSRPIFKNYIEANHI-EVSQKELEEVE------ITEEDEEKILELAKDPWIREKIIASIAPSIYGHWEIKEA 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 482 ILLQLFGGTKKKHATLGRqnFRSEIHLLLCGDPGTSKSQMLQYVFNLVPRSQYTSGRGSSAVGLTAYVTKDPETRQLVLQ 561
Cdd:NF040949 303 IALLLFGGVPKVLPDGTR--IRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLE 380
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 562 TGALVLADNGVCCIDEFDKMNDSTRSVLHEVMEQQTLSIAKAGIICQLNARTSILAAANPAESQWNKRKNIIDNVQLPHT 641
Cdd:NF040949 381 AGALVLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPT 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 642 LLSRFDLIFLVLDPQDEIFDKRLASHLVSLyyvtrHEEEDT---MFDMSVLRDYIAYAREHLSPTLSDEAQQRLIQAYVD 718
Cdd:NF040949 461 ILSRFDLIFVIRDKPNEERDRRLARHILDV-----HSGKEKvkpEIDPDLLKKYIAYARKYVRPKLTEEAKKLIEDFYVE 535
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 719 MRKVGAGRGQ----ISAYPRQLESLIRLSEAHAKVRLSNQVELLDVEEAWRLHREALKQSATDPLSGKIDVGILTTGLST 794
Cdd:NF040949 536 MRKSSKSSEDpdspIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLMLAFLESVGIDVETGKIDIDTIMTGKPK 615
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17137242 795 AARKKRADLVAAIKENLKKKGKVltvpyqKLFSDIKEGSQIMITREQFEDALKEVQDEGAI 855
Cdd:NF040949 616 SKREKMSKIVEIIKELEEEEECV------KIKELIKEAEKKGIDEEKVEELISDLKRSGEI 670
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
132-856 |
2.03e-160 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 491.82 E-value: 2.03e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 132 IPEKGSETTDPVSESSQAPQLVvwgtNVVVSQCKSKFKSFIMRFIDPSA------EQDEISENIDVnqpLYLQKLEEI-- 203
Cdd:PTZ00111 60 IGDLGRETFMDQRDVARLPFLL----DNRLEELSERFTNFLKNFTEFSDvlefkdEQQSKPEYTEL---YYLWKLMNFik 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 204 HTLEEPYLNL--------NCAHLKTFDQDLYRQLICYPQEVIPGFDMAI----NEMFFERYPAALLEHQI---QVRPFNA 268
Cdd:PTZ00111 133 ENLRDHSTGYsrilpfevDLMHVYSFDKVLYKLLVTFPADCIAELDKVLvklfNELLSKHYSDLSLENNSffpRARLMNK 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 269 DKTRNMRSLNPEDMDQLISISGMVIRSSNVIPEMREAFFSC-----------NICSFSTTVEVDRGRINQPTLCTNCNTN 337
Cdd:PTZ00111 213 PVSDCVGNLEPSMADSLVQFSGTVVRQTWIVPEITMACFRCrgqkkiglndyQPCTCEHYEYVIQGEVNEPLLCNECNSK 292
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 338 HCFRLIHNRSEFTDKQLVKLQESPDDMAAGQTP--------------------HNVLLYAHNDLVDKVQPGDRVTVTGIY 397
Cdd:PTZ00111 293 YTFELNHNMCVYSTKKIVKLLQSNSSLNNPDKDgldnsvdnsglngeiymkdnEVINLNLYDDLIDSVKTGDRVTVVGIL 372
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 398 RATPLKTGGLSSSVKSVYKTHVDVVHFRKVDNKRLYEDEEGKDHI-----FPPERVELLQLLAKKPDIYDRLARAIAPSI 472
Cdd:PTZ00111 373 KVTPIRTSTTRRTLKSLYTYFVNVIHVKVINSTNANQPEKGLKYLgnendFSDLQVYKILELSRNPMIYRILLDSFAPSI 452
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 473 YENDDIKKGILLQLFGGT-------KKKHATLGRQNFRSEIHLLLCGDPGTSKSQMLQYVFNLVPRSQYTSGRGSSAVGL 545
Cdd:PTZ00111 453 KARNNVKIGLLCQLFSGNknssdfnKSPDACYKVDNFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGL 532
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 546 TAYVT-KDPETRQLVLQTGALVLADNGVCCIDEFDKMNDSTRSVLHEVMEQQTLSIAKAGIICQLNARTSILAAANPAES 624
Cdd:PTZ00111 533 TASIKfNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINS 612
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 625 QWNKRKNIIDNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASHLVSLYYV-----------------TRHEEEDT----- 682
Cdd:PTZ00111 613 RYNKNKAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLISLSIAKDFLLphmtgsgndedtydrsnTMHVEDESlrsek 692
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 683 ---MFDMSVLRDYIAYAREHLSPTLSDEAQQRLIQAYVDMRKVG------------------------AGRGQISAYPRQ 735
Cdd:PTZ00111 693 dynKNDLDMLRMYIKFSKLHCFPKLSDEAKKVITREYVKMRQGNfqtsnldelehaqedddddlyyqsSGTRMIYVSSRM 772
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 736 LESLIRLSEAHAKVRLSNQVELLDVEEAWRLHREALKQSATDPLSGKIDVGILTTGLSTAARKKRAD-----LVAAIKEN 810
Cdd:PTZ00111 773 ISSIIRISVSLARMRLSTVVTPADALQAVQIVKSSTFQSLVDPTTGKIDFDQLHQGITTNKMQQLNQmyeqvLSVLTRSS 852
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|.
gi 17137242 811 LKKKGKVLTVP-----YQKLFSDIKEGSQIMItREQFEDALKEVQDEGAIV 856
Cdd:PTZ00111 853 NQDSNKSLDLNevlslCHKTFKDNRDHKDGEI-YKLISEVLNKMVQEGTAV 902
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
447-672 |
3.52e-132 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 393.82 E-value: 3.52e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 447 RVELLQLLAKKPDIYDRLARAIAPSIYENDDIKKGILLQLFGGTKKKHATLGRqnFRSEIHLLLCGDPGTSKSQMLQYVF 526
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTR--LRGDINVLLVGDPGTAKSQLLKYVE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 527 NLVPRSQYTSGRGSSAVGLTAYVTKDPETRQLVLQTGALVLADNGVCCIDEFDKMNDSTRSVLHEVMEQQTLSIAKAGII 606
Cdd:pfam00493 79 KIAPRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIV 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 17137242 607 CQLNARTSILAAANPAESQWNKRKNIIDNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASHLVSLY 672
Cdd:pfam00493 159 ATLNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
165-267 |
5.22e-20 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 85.42 E-value: 5.22e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 165 KSKFKSFIMRFIDPSAeqdeisenidvNQPLYLQKLEEIHTLEEPYLNLNCAHLKTFDQDLYRQLICYPQEVIPGFDMAI 244
Cdd:pfam14551 1 KRKFKDFLEEFREDGD-----------GEFKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEAL 69
|
90 100
....*....|....*....|....*.
gi 17137242 245 NEMFFE---RYPAALLEHQIQVRPFN 267
Cdd:pfam14551 70 KEVVKElseDPDYAEEEKEFQVRFYN 95
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
2-150 |
1.09e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 42.85 E-value: 1.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 2 SSPARSPSVGGATPKQGARTPTRGIASQDVETPMRMGPGRAVRPSDNISLPPTSPGniSLPATSPARGLGAnmseidlss 81
Cdd:PHA03307 166 AASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPA--PAPGRSAADDAGA--------- 234
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 17137242 82 plnygTPSSMGSIRTPRSGIRGTPLRARP---DIRTDKRIRQVAIGGGSGLEPIPEKgSETTDPVSESSQAP 150
Cdd:PHA03307 235 -----SSSDSSSSESSGCGWGPENECPLPrpaPITLPTRIWEASGWNGPSSRPGPAS-SSSSPRERSPSPSP 300
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
270-772 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 710.18 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 270 KTRNMRSLNPEDMDQLISISGMVIRSSNVIPEMREAFFSCNICSFSTTVEVDRGRINQPTLCTN--CNTNHCFRLIHNRS 347
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQSGRETEPTVCPPreCQSPTPFSLNHERS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 348 EFTDKQLVKLQESPDDMAAGQTPHNVLLYAHNDLVDKVQPGDRVTVTGIYRATPLKTGGLSSSVKSVYKTHVDVVHFRKV 427
Cdd:smart00350 81 TFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVPYGFKLNTVKGLPVFATYIEANHVRKL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 428 DNKRLYEDEEGKDHIFPPERVELLQLLAKKPDIYDRLARAIAPSIYENDDIKKGILLQLFGGTKKKhaTLGRQNFRSEIH 507
Cdd:smart00350 161 DYKRSFEDSSFSVQSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKN--LPDGMKIRGDIN 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 508 LLLCGDPGTSKSQMLQYVFNLVPRSQYTSGRGSSAVGLTAYVTKDPETRQLVLQTGALVLADNGVCCIDEFDKMNDSTRS 587
Cdd:smart00350 239 ILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDDSDRT 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 588 VLHEVMEQQTLSIAKAGIICQLNARTSILAAANPAESQWNKRKNIIDNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASH 667
Cdd:smart00350 319 AIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRELAKH 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 668 LVSLyYVTRHEEEDT----MFDMSVLRDYIAYAREHLSPTLSDEAQQRLIQAYVDMRKVGA---GRGQISAYPRQLESLI 740
Cdd:smart00350 399 VVDL-HRYSHPEEDEafepPLSQEKLRKYIAYAREKIKPKLSEEAADKLVKAYVDLRKEDSqteSRSSIPITVRQLESII 477
|
490 500 510
....*....|....*....|....*....|..
gi 17137242 741 RLSEAHAKVRLSNQVELLDVEEAWRLHREALK 772
Cdd:smart00350 478 RLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
196-855 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 610.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 196 YLQKLEEI--HTLEEPYLNLNCAHLKTFDQDLYRQLICYPQEVIPGFDMAINEmfFERYPAALLEHQIQVRPFNADKTRN 273
Cdd:COG1241 18 YRDEILELaqEYPEKRSLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEALRE--IDLEPYDVSLGDAHVRITNLPETVP 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 274 MRSLNPEDMDQLISISGMVIRSSNVIPEMREAFFSCNICSFSTTVEVDRGRINQPTLCTNCNTNHCFRLIHNRSEFTDKQ 353
Cdd:COG1241 96 IRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTETYVPQTGEKLQEPHECPGCGRQGPFKLLPEKSEFIDAQ 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 354 LVKLQESPDDMAAGQTPHNVLLYAHNDLVDKVQPGDRVTVTGIYRATPLKTGGLSSSVksvYKTHVDVVHFRKVDnkRLY 433
Cdd:COG1241 176 KIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQRTSGRGKSTI---FDLYLEANSIEVEE--KEF 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 434 EDEEgkdhIFPPERVELLQLlAKKPDIYDRLARAIAPSIYENDDIKKGILLQLFGGTKKKHATLGRqnFRSEIHLLLCGD 513
Cdd:COG1241 251 EEIE----ITEEDEEKIKEL-SKDPDIYEKIIASIAPSIYGYEEIKEAIALQLFGGVPKVLPDGSR--IRGDIHILLVGD 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 514 PGTSKSQMLQYVFNLVPRSQYTSGRGSSAVGLTAYVTKDPE-TRQLVLQTGALVLADNGVCCIDEFDKMNDSTRSVLHEV 592
Cdd:COG1241 324 PGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDDFgTGRWTLEAGALVLADGGLACIDELDKMREEDRSALHEA 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 593 MEQQTLSIAKAGIICQLNARTSILAAANPAESQWNKRKNIIDNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASHLVSLY 672
Cdd:COG1241 404 MEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKPDEERDRELARHILKVH 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 673 Y--------VTRHEEEDT-MFDMSVLRDYIAYAREHLSPTLSDEAQQRLIQAYVDMRKVGAGRGQ-ISAYPRQLESLIRL 742
Cdd:COG1241 484 RagelleqeIEEETEEVKpEIDPDLLRKYIAYARRNVFPVLTEEAKDLIEDFYVDMRKKGEDEDSpVPITARQLEALIRL 563
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 743 SEAHAKVRLSNQVELLDVEEAWRLHREALKQSATDPLSGKIDVGILTTGLSTAARKKRADLVAAIKENLKKKGKvlTVPY 822
Cdd:COG1241 564 AEASARMRLSDTVTEEDAERAIRLVDSCLKDVGVDPETGKFDIDVIETGTSKSQRDKMKLIKDIIKELEEESSG--GAPI 641
|
650 660 670
....*....|....*....|....*....|...
gi 17137242 823 QKLfsdIKEGSQIMITREQFEDALKEVQDEGAI 855
Cdd:COG1241 642 EDV---IEEAEEEGIDREKAEELIEKLKRKGEI 671
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
463-770 |
0e+00 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 596.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 463 RLARAIAPSIYENDDIKKGILLQLFGGTKKKHATlGRQNFRSEIHLLLCGDPGTSKSQMLQYVFNLVPRSQYTSGRGSSA 542
Cdd:cd17755 1 RLARSIAPSIYELEDVKKGILLQLFGGTRKDFTK-TGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 543 VGLTAYVTKDPETRQLVLQTGALVLADNGVCCIDEFDKMNDSTRSVLHEVMEQQTLSIAKAGIICQLNARTSILAAANPA 622
Cdd:cd17755 80 VGLTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 623 ESQWNKRKNIIDNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASHLVSLYYVTRHEE-EDTMFDMSVLRDYIAYAREHLS 701
Cdd:cd17755 160 GSRYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLYLEDTPEHiQDEVLDVEVLTDYISYAREHIH 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 702 PTLSDEAQQRLIQAYVDMRKVGAG-RGQISAYPRQLESLIRLSEAHAKVRLSNQVELLDVEEAWRLHREA 770
Cdd:cd17755 240 PKLSEEAAQELVQAYVDMRKMGSDaRKRITATPRQLESLIRLAEAHAKMRLSNVVEAEDVEEAVRLIREA 309
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
167-855 |
0e+00 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 565.32 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 167 KFKSFIMRFIDPSaeqdeisenidvNQPLYLQKLEEIHTLEEPYLNLNCAHLKTFDQDLYRQLICYPQEVIPGFDMAINE 246
Cdd:NF040949 4 KFKEFIRTFRDSF------------GNEKYKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALKE 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 247 MFFERYPA-ALLEHQIQVRPFNADKTRNMRSLNPEDMDQLISISGMVIRSSNVIPEMREAFFSCNIC--SFSTTVEVDRG 323
Cdd:NF040949 72 IVEEEDPEyAEEVAKFHVRFRNLPRTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCgcEFEWPEEEEES 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 324 --RINQPTLCTNCNTNHCFRLIHNRSEFTDKQLVKLQESPDDMAAGQTPHNVLLYAHNDLVDKVQPGDRVTVTGIYRATP 401
Cdd:NF040949 152 yeIVEPPTVCPVCGKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIKP 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 402 lkTGGLSSSVKSVYKTHVDVVHFrKVDNKRLYEDEegkdhiFPPERVELLQLLAKKPDIYDRLARAIAPSIYENDDIKKG 481
Cdd:NF040949 232 --DSSLKKGSRPIFKNYIEANHI-EVSQKELEEVE------ITEEDEEKILELAKDPWIREKIIASIAPSIYGHWEIKEA 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 482 ILLQLFGGTKKKHATLGRqnFRSEIHLLLCGDPGTSKSQMLQYVFNLVPRSQYTSGRGSSAVGLTAYVTKDPETRQLVLQ 561
Cdd:NF040949 303 IALLLFGGVPKVLPDGTR--IRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLE 380
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 562 TGALVLADNGVCCIDEFDKMNDSTRSVLHEVMEQQTLSIAKAGIICQLNARTSILAAANPAESQWNKRKNIIDNVQLPHT 641
Cdd:NF040949 381 AGALVLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPT 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 642 LLSRFDLIFLVLDPQDEIFDKRLASHLVSLyyvtrHEEEDT---MFDMSVLRDYIAYAREHLSPTLSDEAQQRLIQAYVD 718
Cdd:NF040949 461 ILSRFDLIFVIRDKPNEERDRRLARHILDV-----HSGKEKvkpEIDPDLLKKYIAYARKYVRPKLTEEAKKLIEDFYVE 535
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 719 MRKVGAGRGQ----ISAYPRQLESLIRLSEAHAKVRLSNQVELLDVEEAWRLHREALKQSATDPLSGKIDVGILTTGLST 794
Cdd:NF040949 536 MRKSSKSSEDpdspIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLMLAFLESVGIDVETGKIDIDTIMTGKPK 615
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17137242 795 AARKKRADLVAAIKENLKKKGKVltvpyqKLFSDIKEGSQIMITREQFEDALKEVQDEGAI 855
Cdd:NF040949 616 SKREKMSKIVEIIKELEEEEECV------KIKELIKEAEKKGIDEEKVEELISDLKRSGEI 670
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
132-856 |
2.03e-160 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 491.82 E-value: 2.03e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 132 IPEKGSETTDPVSESSQAPQLVvwgtNVVVSQCKSKFKSFIMRFIDPSA------EQDEISENIDVnqpLYLQKLEEI-- 203
Cdd:PTZ00111 60 IGDLGRETFMDQRDVARLPFLL----DNRLEELSERFTNFLKNFTEFSDvlefkdEQQSKPEYTEL---YYLWKLMNFik 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 204 HTLEEPYLNL--------NCAHLKTFDQDLYRQLICYPQEVIPGFDMAI----NEMFFERYPAALLEHQI---QVRPFNA 268
Cdd:PTZ00111 133 ENLRDHSTGYsrilpfevDLMHVYSFDKVLYKLLVTFPADCIAELDKVLvklfNELLSKHYSDLSLENNSffpRARLMNK 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 269 DKTRNMRSLNPEDMDQLISISGMVIRSSNVIPEMREAFFSC-----------NICSFSTTVEVDRGRINQPTLCTNCNTN 337
Cdd:PTZ00111 213 PVSDCVGNLEPSMADSLVQFSGTVVRQTWIVPEITMACFRCrgqkkiglndyQPCTCEHYEYVIQGEVNEPLLCNECNSK 292
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 338 HCFRLIHNRSEFTDKQLVKLQESPDDMAAGQTP--------------------HNVLLYAHNDLVDKVQPGDRVTVTGIY 397
Cdd:PTZ00111 293 YTFELNHNMCVYSTKKIVKLLQSNSSLNNPDKDgldnsvdnsglngeiymkdnEVINLNLYDDLIDSVKTGDRVTVVGIL 372
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 398 RATPLKTGGLSSSVKSVYKTHVDVVHFRKVDNKRLYEDEEGKDHI-----FPPERVELLQLLAKKPDIYDRLARAIAPSI 472
Cdd:PTZ00111 373 KVTPIRTSTTRRTLKSLYTYFVNVIHVKVINSTNANQPEKGLKYLgnendFSDLQVYKILELSRNPMIYRILLDSFAPSI 452
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 473 YENDDIKKGILLQLFGGT-------KKKHATLGRQNFRSEIHLLLCGDPGTSKSQMLQYVFNLVPRSQYTSGRGSSAVGL 545
Cdd:PTZ00111 453 KARNNVKIGLLCQLFSGNknssdfnKSPDACYKVDNFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGL 532
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 546 TAYVT-KDPETRQLVLQTGALVLADNGVCCIDEFDKMNDSTRSVLHEVMEQQTLSIAKAGIICQLNARTSILAAANPAES 624
Cdd:PTZ00111 533 TASIKfNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINS 612
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 625 QWNKRKNIIDNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASHLVSLYYV-----------------TRHEEEDT----- 682
Cdd:PTZ00111 613 RYNKNKAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLISLSIAKDFLLphmtgsgndedtydrsnTMHVEDESlrsek 692
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 683 ---MFDMSVLRDYIAYAREHLSPTLSDEAQQRLIQAYVDMRKVG------------------------AGRGQISAYPRQ 735
Cdd:PTZ00111 693 dynKNDLDMLRMYIKFSKLHCFPKLSDEAKKVITREYVKMRQGNfqtsnldelehaqedddddlyyqsSGTRMIYVSSRM 772
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 736 LESLIRLSEAHAKVRLSNQVELLDVEEAWRLHREALKQSATDPLSGKIDVGILTTGLSTAARKKRAD-----LVAAIKEN 810
Cdd:PTZ00111 773 ISSIIRISVSLARMRLSTVVTPADALQAVQIVKSSTFQSLVDPTTGKIDFDQLHQGITTNKMQQLNQmyeqvLSVLTRSS 852
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|.
gi 17137242 811 LKKKGKVLTVP-----YQKLFSDIKEGSQIMItREQFEDALKEVQDEGAIV 856
Cdd:PTZ00111 853 NQDSNKSLDLNevlslCHKTFKDNRDHKDGEI-YKLISEVLNKMVQEGTAV 902
|
|
| MCM |
cd17706 |
MCM helicase family; MCM helicases are a family of helicases that play an important role in ... |
463-770 |
7.88e-138 |
|
MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350658 [Multi-domain] Cd Length: 311 Bit Score: 412.12 E-value: 7.88e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 463 RLARAIAPSIYENDDIKKGILLQLFGGTKKKHATLGRqnFRSEIHLLLCGDPGTSKSQMLQYVFNLVPRSQYTSGRGSSA 542
Cdd:cd17706 1 ILADSIAPSIYGHEDVKKAVLLQLFGGVQKILEDGTR--IRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 543 VGLTAYVTKDPETRQLVLQTGALVLADNGVCCIDEFDKMNDSTRSVLHEVMEQQTLSIAKAGIICQLNARTSILAAANPA 622
Cdd:cd17706 79 AGLTAAVVRDSETGEWYLEAGALVLADGGVCCIDEFDKMKELDRTALHEAMEQQTISIAKAGIVTTLNARCSILAAANPK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 623 ESQWNKRKNIIDNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASHLVSLY------YVTRHEEEDTMFDMSVLRDYIAYA 696
Cdd:cd17706 159 GGRYNPKLSPIENINLPSPLLSRFDLIFVIRDDPDEERDEELAEHIIDLHrgsdpeEQVKPEEDGIPIDIELLRKYILYA 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 17137242 697 ReHLSPTLSDEAQQRLIQAYVDMRKVGAGRGQISAYPRQLESLIRLSEAHAKVRLSNQVELLDVEEAWRLHREA 770
Cdd:cd17706 239 R-QIHPKISEEAREKLVRWYVELRKESERRSTIPITARQLESVIRLAEAHAKMRLSEVVTEEDVEEAIRLVRHS 311
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
447-672 |
3.52e-132 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 393.82 E-value: 3.52e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 447 RVELLQLLAKKPDIYDRLARAIAPSIYENDDIKKGILLQLFGGTKKKHATLGRqnFRSEIHLLLCGDPGTSKSQMLQYVF 526
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTR--LRGDINVLLVGDPGTAKSQLLKYVE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 527 NLVPRSQYTSGRGSSAVGLTAYVTKDPETRQLVLQTGALVLADNGVCCIDEFDKMNDSTRSVLHEVMEQQTLSIAKAGII 606
Cdd:pfam00493 79 KIAPRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIV 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 17137242 607 CQLNARTSILAAANPAESQWNKRKNIIDNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASHLVSLY 672
Cdd:pfam00493 159 ATLNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
463-766 |
1.88e-121 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 369.43 E-value: 1.88e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 463 RLARAIAPSIYENDDIKKGILLQLFGGTKKKHATLgrqNFRSEIHLLLCGDPGTSKSQMLQYVFNLVPRSQYTSGRGSSA 542
Cdd:cd17758 1 KLAASIAPEIYGHEDVKKALLLLLVGGVDKRGDGM---KIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 543 VGLTAYVTKDPETRQLVLQTGALVLADNGVCCIDEFDKMNDSTRSVLHEVMEQQTLSIAKAGIICQLNARTSILAAANPA 622
Cdd:cd17758 78 VGLTAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 623 ESQWNKRKNIIDNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASHLVslyYVTRHEEEDTM----FDMSVLRDYIAYARE 698
Cdd:cd17758 158 YGRYNPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVT---YVHQHNKQPDSdfepLDPKLLRAYIALAKR 234
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 17137242 699 hLSPTLSDEAQQRLIQAYVDMRKVGAGRGQIS-AYPRQLESLIRLSEAHAKVRLSNQVELLDVEEAWRL 766
Cdd:cd17758 235 -KRPTVPPALADYIVQAYVEMRQEAKRSKDFTfTTPRTLLAILRLSQALARLRLSDSVEIDDVEEALRL 302
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
463-774 |
3.03e-119 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 363.61 E-value: 3.03e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 463 RLARAIAPSIYENDDIKKGILLQLFGGTKKKhaTLGRQNFRSEIHLLLCGDPGTSKSQMLQYVFNLVPRSQYTSGRGSSA 542
Cdd:cd17757 1 NLVRSIAPSIYGHEEVKKGILLMLLGGVHKI--TREGISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 543 VGLTAYVTKDPETRQLVLQTGALVLADNGVCCIDEFDKMNDSTRSVLHEVMEQQTLSIAKAGIICQLNARTSILAAANPA 622
Cdd:cd17757 79 AGLTAAVVRDEETGDFVIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 623 ESQWNKRKNIIDNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASHLVSLyYVTRHEEEDTMFDMSVLRDYIAYAREhLSP 702
Cdd:cd17757 159 GGRYDRSKSLKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHIVDL-HSKREEAIEPPFTAEQLKRYIAYART-FKP 236
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 17137242 703 TLSDEAQQRLIQAYVDMRKVGAGRGQISAYP---RQLESLIRLSEAHAKVRLSNQVELLDVEEAWRLhreaLKQS 774
Cdd:cd17757 237 KLTKEAKDELVEQYKELRQDDASGSTRSSYRitvRQLESLIRLSEAIARLHCSDEVTPEHVEEAARL----LKKS 307
|
|
| MCM_arch |
cd17761 |
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ... |
462-768 |
5.94e-117 |
|
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork
Pssm-ID: 350667 [Multi-domain] Cd Length: 308 Bit Score: 357.92 E-value: 5.94e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 462 DRLARAIAPSIYENDDIKKGILLQLFGGTKKKHATLGRqnFRSEIHLLLCGDPGTSKSQMLQYVFNLVPRSQYTSGRGSS 541
Cdd:cd17761 1 EKIISSIAPSIYGHEDVKEAIALQLFGGVPKVLPDGTR--IRGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGST 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 542 AVGLTAYVTKDPETRQLVLQTGALVLADNGVCCIDEFDKMNDSTRSVLHEVMEQQTLSIAKAGIICQLNARTSILAAANP 621
Cdd:cd17761 79 AAGLTAAVVRDEGTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRSALHEAMEQQTISIAKAGIVATLNARAAVLAAANP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 622 AESQWNKRKNIIDNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASHLVSLYYVTRHEEEDTMFDMSVLRDYIAYAREHLS 701
Cdd:cd17761 159 KFGRFDSYRPVAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLANHILDTHSGGEMREIKPEIDPDLLRKYIAYARKNVR 238
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 17137242 702 PTLSDEAQQRLIQAYVDMRKVGAGRGQ-ISAYPRQLESLIRLSEAHAKVRLSNQVELLDVEEAWRLHR 768
Cdd:cd17761 239 PVLTEEAKQLIKDFYVEMRKSGQETPSpVPITARQLEALVRLSEASARMRLSQEVTLEDAERAIRIML 306
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
463-766 |
5.33e-114 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 350.53 E-value: 5.33e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 463 RLARAIAPSIYENDDIKKGILLQLFGGTKKKHATLGRqnFRSEIHLLLCGDPGTSKSQMLQYVFNLVPRSQYTSGRGSSA 542
Cdd:cd17756 1 IISKSIAPSIYGNEDIKKAIACLLFGGSRKRLPDGMR--LRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 543 VGLTAYVTKDPETRQLVLQTGALVLADNGVCCIDEFDKMNDSTRSVLHEVMEQQTLSIAKAGIICQLNARTSILAAANPA 622
Cdd:cd17756 79 AGLTASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANPV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 623 ESQWNKRKNIIDNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASHLVSLYY----VTRHEEEDTMFDMSVLRDYIAYARE 698
Cdd:cd17756 159 FGRYDDLKTPGDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIHAsarkASQSQENEGEIPISKLKRYIAYCRA 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 17137242 699 HLSPTLSDEAQQRLIQAYVDMRK----VGAGRGQISAYP---RQLESLIRLSEAHAKVRLSNQVELLDVEEAWRL 766
Cdd:cd17756 239 KCAPRLSEEAAEKLSNHYVTIRKdvrqNELESDNRSSIPitvRQLEAIIRISESLAKMELSPIATEKHVEEAIRL 313
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
464-770 |
1.75e-105 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 327.50 E-value: 1.75e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 464 LARAIAPSIYENDDIKKGILLQLFGGTKKKHATlgRQNFRSEIHLLLCGDPGTSKSQMLQYVFNLVPRSQYTSGRGSSAV 543
Cdd:cd17754 2 LSKSLAPSIYGHEYIKKAILLMLLGGVEKNLEN--GSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 544 GLTAYVTKDPETRQLVLQTGALVLADNGVCCIDEFDKMNDSTRSVLHEVMEQQTLSIAKAGIICQLNARTSILAAANPAE 623
Cdd:cd17754 80 GLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVY 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 624 SQWNKRKNIIDNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASHLVSLYyvtRHeeedtmfdMSVLRDYIAYAREHLSPT 703
Cdd:cd17754 160 GRYDVYKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMH---RY--------IKFLRKYIHYAKERIKPK 228
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17137242 704 LSDEAQQRLIQAYVDMRKVGA-GRGQISAYP---RQLESLIRLSEAHAKVRLSNQVELLDVEEAWRLHREA 770
Cdd:cd17754 229 LTQEAAEYIAEEYADLRNDDNtKTDKARTSPitaRTLETLIRLATAHAKARLSKTVDKVDAEVALNLLRFA 299
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
463-766 |
1.32e-104 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 326.33 E-value: 1.32e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 463 RLARAIAPSIYENDDIKKGILLQLFGGTKKKhaTLGRQNFRSEIHLLLCGDPGTSKSQMLQYVFNLVPRSQYTSGRGSSA 542
Cdd:cd17753 1 RIINSIAPSIYGHDDIKTAIALALFGGVAKN--PGGKHRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 543 VGLTAYVTKDPETRQLVLQTGALVLADNGVCCIDEFDKMNDSTRSVLHEVMEQQTLSIAKAGIICQLNARTSILAAANPA 622
Cdd:cd17753 79 VGLTASVRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 623 ESQWNKRKNIIDNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASHLVSlYYVTRHEEEDTMFDMS--------------- 687
Cdd:cd17753 159 GGRYNPTLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVG-SHVRSHPENDEDREGEeeknqrqrpketkve 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 688 -----VLRDYIAYAREHLSPTLSDEAQQRLIQAYVDMRKVGAGRGQISAYPRQLESLIRLSEAHAKVRLSNQVELLDVEE 762
Cdd:cd17753 238 pipqeLLRKYIHYAREKVRPKLNQMDMDKVSRVYADLRKESMATGSLPITVRHLESIIRISEAHAKMHLREYVSEEDVDM 317
|
....
gi 17137242 763 AWRL 766
Cdd:cd17753 318 AIRV 321
|
|
| MCM8 |
cd17759 |
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ... |
463-770 |
3.01e-87 |
|
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350665 [Multi-domain] Cd Length: 289 Bit Score: 279.42 E-value: 3.01e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 463 RLARAIAPSIYENDDIKKGILLQLFGGTKKKHATLGRQNFRSEIHLLLCGDPGTSKSQMLQYVFNLVPRSQYTSGRGSSA 542
Cdd:cd17759 1 LIVNSLCPAIYGHELVKAGLLLSLFGGKQKYADDKNRIPIRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 543 VGLTAYVTKDPETRQLVLQTGALVLADNGVCCIDEFDKMnDSTRSVLHEVMEQQTLSIAKAGIICQLNARTSILAAANPA 622
Cdd:cd17759 81 SGLTVTLTKDGRSGDFALEAGALVLGDQGICGIDEFDKM-GSQHQALLEAMEQQSVSLAKAGVVCSLPARTSVIAAANPV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 623 ESQWNKRKNIIDNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASHlvslyyvtrheeedtmfdMSVLRDYIAYAREHLSP 702
Cdd:cd17759 160 GGHYNKGKTVSENLKMGPALLSRFDLVFILLDTPSEEHDHLLSEH------------------HQLLRKYISYARQYVNP 221
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 703 TLSDEAQQRLIQAYVDMRK--VGAGRGQISAypRQLESLIRLSEAHAKVRLSNQVELLDVEEAWRLHREA 770
Cdd:cd17759 222 VLSKDASEALQEFYLELRKqnQLADSSPITT--RQLESLIRLTEARARLELREEATKEDAEDVIEIMKES 289
|
|
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
464-760 |
3.15e-76 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 250.16 E-value: 3.15e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 464 LARAIAPSIYENDDIKKGILLQLFGGTKKKHATLGRqnFRSEIHLLLCGDPGTSKSQMLQYVFNLVPRSQYTSGRGSSAV 543
Cdd:cd17760 2 ILASLCPQVFGLYNVKLAVAMVLAGGVQRIDASGTR--VRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTSA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 544 GLTAYVTKDpeTRQLVLQTGALVLADNGVCCIDEFDKMNDSTRSVLHEVMEQQTLSIAKAGIICQLNARTSILAAANPaE 623
Cdd:cd17760 80 GLTVTAVKD--GGEWNLEAGALVLADGGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP-K 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 624 SQWNKRKNIIDNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASHLVSLYYVTRheEEDTMFDMSVLRDYIAYAREhLSPT 703
Cdd:cd17760 157 GQYDPNESISVNIALASPLLSRFDLVLVLLDTKNEDWDRIISSFILENKGEPS--KSSKLWSMEKMRTYFCLIKN-LRPV 233
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 17137242 704 LSDEAQQRLIQaYVDMRKVGAGRGQISAYPRQLESLIRLSEAHAKVRLSNQVELLDV 760
Cdd:cd17760 234 LSDEANAILLR-YYQLQRQSDCRNAARTTIRMLESLIRLAEAHARLMFRETVTEEDA 289
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
273-401 |
8.85e-53 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 179.60 E-value: 8.85e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 273 NMRSLNPEDMDQLISISGMVIRSSNVIPEMREAFFSCNICSFSTTVevdrgRINQPTLCTN--CNTNHCFRLIHNRSEFT 350
Cdd:pfam17207 1 SIRDLRSEHIGKLVSVSGIVTRTSEVRPKLKKATFTCRKCGHTVGV-----KITEPTKCPNpeCGNKDPFKLVHEKSKFV 75
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 17137242 351 DKQLVKLQESPDDMAAGQTPHNVLLYAHNDLVDKVQPGDRVTVTGIYRATP 401
Cdd:pfam17207 76 DFQKIKIQESPEEVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGIYRVVP 126
|
|
| MCM_lid |
pfam17855 |
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins. |
687-771 |
2.51e-34 |
|
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
Pssm-ID: 465534 [Multi-domain] Cd Length: 86 Bit Score: 126.12 E-value: 2.51e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 687 SVLRDYIAYAREHLSPTLSDEAQQRLIQAYVDMRKVGAG-RGQISAYPRQLESLIRLSEAHAKVRLSNQVELLDVEEAWR 765
Cdd:pfam17855 1 ELLRKYIAYAREKIKPKLSEEAREKLVDAYVELRKESTGsGSSIPITVRQLESLIRLSEAHAKMRLSEIVTEEDVEEAIR 80
|
....*.
gi 17137242 766 LHREAL 771
Cdd:pfam17855 81 LLKESL 86
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
165-267 |
5.22e-20 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 85.42 E-value: 5.22e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 165 KSKFKSFIMRFIDPSAeqdeisenidvNQPLYLQKLEEIHTLEEPYLNLNCAHLKTFDQDLYRQLICYPQEVIPGFDMAI 244
Cdd:pfam14551 1 KRKFKDFLEEFREDGD-----------GEFKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEAL 69
|
90 100
....*....|....*....|....*.
gi 17137242 245 NEMFFE---RYPAALLEHQIQVRPFN 267
Cdd:pfam14551 70 KEVVKElseDPDYAEEEKEFQVRFYN 95
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
507-646 |
5.86e-08 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 52.29 E-value: 5.86e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 507 HLLLCGDPGTSKSQMLQYVfnlvprSQYTSGRGSSAVGLTAYVTKD-------PETRQLVLQTGALVLADN--GVCCIDE 577
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERL------AAALSNRPVFYVQLTRDTTEEdlfgrrnIDPGGASWVDGPLVRAARegEIAVLDE 74
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 578 FDKMNDSTRSVLHEVMEQQTLSIAKAGIICQL-NARTSILAAANPAESQWNKrkniidnvqLPHTLLSRF 646
Cdd:pfam07728 75 INRANPDVLNSLLSLLDERRLLLPDGGELVKAaPDGFRLIATMNPLDRGLNE---------LSPALRSRF 135
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
507-775 |
1.28e-05 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 47.85 E-value: 1.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 507 HLLLCGDPGTSKSQMLQ---YVFNL-VPRSQYTSG-RGSSAVGLTAYvtkDPETRQLVLQTGAL----VLAdngvcciDE 577
Cdd:COG0714 33 HLLLEGVPGVGKTTLAKalaRALGLpFIRIQFTPDlLPSDILGTYIY---DQQTGEFEFRPGPLfanvLLA-------DE 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 578 FDKMNDSTRSVLHEVMEQQTLSIakAGIICQLNARTSILAAANPAEsQWNKRkniidnvQLPHTLLSRFdLIFLVLDPQD 657
Cdd:COG0714 103 INRAPPKTQSALLEAMEERQVTI--PGGTYKLPEPFLVIATQNPIE-QEGTY-------PLPEAQLDRF-LLKLYIGYPD 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 658 -----EIFDKRLASHLVSLYYVTRHEEedtmfdmsvLRDYIAYARE-HLSPTLSDEAqQRLIQAYVDMR--KVGAGrgqi 729
Cdd:COG0714 172 aeeerEILRRHTGRHLAEVEPVLSPEE---------LLALQELVRQvHVSEAVLDYI-VDLVRATREHPdlRKGPS---- 237
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 17137242 730 sayPRQLESLIRLSEAHAKVRLSNQVELLDVEEAWRL---HREALKQSA 775
Cdd:COG0714 238 ---PRASIALLRAARALALLDGRDYVTPDDVKAVAGPvlkHRLILSPEA 283
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
2-150 |
1.09e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 42.85 E-value: 1.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 2 SSPARSPSVGGATPKQGARTPTRGIASQDVETPMRMGPGRAVRPSDNISLPPTSPGniSLPATSPARGLGAnmseidlss 81
Cdd:PHA03307 166 AASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPA--PAPGRSAADDAGA--------- 234
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 17137242 82 plnygTPSSMGSIRTPRSGIRGTPLRARP---DIRTDKRIRQVAIGGGSGLEPIPEKgSETTDPVSESSQAP 150
Cdd:PHA03307 235 -----SSSDSSSSESSGCGWGPENECPLPrpaPITLPTRIWEASGWNGPSSRPGPAS-SSSSPRERSPSPSP 300
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
507-652 |
4.96e-03 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 38.28 E-value: 4.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 507 HLLLCGDPGTSKSQMLQYVFNLVPRSQ----YTSGrgsSAVGLTAYVTKDPETRQLVLQTGALVLADNGVCCIDEFDKMN 582
Cdd:cd00009 21 NLLLYGPPGTGKTTLARAIANELFRPGapflYLNA---SDLLEGLVVAELFGHFLVRLLFELAEKAKPGVLFIDEIDSLS 97
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137242 583 DSTRSVLHEVMEQQTLSIAKagiicqlNARTSILAAANPAESQwnkrkniidnvQLPHTLLSRFDLIFLV 652
Cdd:cd00009 98 RGAQNALLRVLETLNDLRID-------RENVRVIGATNRPLLG-----------DLDRALYDRLDIRIVI 149
|
|
| |
