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Conserved domains on  [gi|17136408|ref|NP_476685|]
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pannier, isoform A [Drosophila melanogaster]

Protein Classification

GATA-type transcription factor( domain architecture ID 10078896)

GATA-type transcription factor binds to the DNA consensus sequence [AT]GATA[AG] and may function as a transcription factor/regulator

CATH:  3.30.50.10
PubMed:  31574210
SCOP:  4003617

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
226-276 8.74e-23

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


:

Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 91.28  E-value: 8.74e-23
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|...
gi 17136408 226 CTNCGTRTTTLWRRN-NDGEPVCNACGLYYKLHGVNRPLAMRK-DGIQTRKRK 276
Cdd:cd00202   2 CSNCGTTTTPLWRRGpSGGSTLCNACGLYWKKHGVMRPLSKRKkDQIKRRNRK 54
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
168-212 5.41e-18

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


:

Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 77.80  E-value: 5.41e-18
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*.
gi 17136408 168 ECVNCGAISTPLWRRDG-TGHYLCNACGLYHKMNGMNRPLIKPSKR 212
Cdd:cd00202   1 ACSNCGTTTTPLWRRGPsGGSTLCNACGLYWKKHGVMRPLSKRKKD 46
 
Name Accession Description Interval E-value
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
226-276 8.74e-23

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 91.28  E-value: 8.74e-23
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|...
gi 17136408 226 CTNCGTRTTTLWRRN-NDGEPVCNACGLYYKLHGVNRPLAMRK-DGIQTRKRK 276
Cdd:cd00202   2 CSNCGTTTTPLWRRGpSGGSTLCNACGLYWKKHGVMRPLSKRKkDQIKRRNRK 54
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
223-270 5.88e-19

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 80.54  E-value: 5.88e-19
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 17136408    223 GLCCTNCGTRTTTLWRRNNDGE-PVCNACGLYYKLHGV-NRPLAMRKDGI 270
Cdd:smart00401   3 GRSCSNCGTTETPLWRRGPSGNkTLCNACGLYYKKHGGlKRPLSLKKDGI 52
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
168-212 5.41e-18

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 77.80  E-value: 5.41e-18
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*.
gi 17136408 168 ECVNCGAISTPLWRRDG-TGHYLCNACGLYHKMNGMNRPLIKPSKR 212
Cdd:cd00202   1 ACSNCGTTTTPLWRRGPsGGSTLCNACGLYWKKHGVMRPLSKRKKD 46
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
164-212 8.29e-15

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 68.60  E-value: 8.29e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 17136408    164 GEGRECVNCGAISTPLWRRDGTGH-YLCNACGLYHKMNG-MNRPLIKPSKR 212
Cdd:smart00401   1 GSGRSCSNCGTTETPLWRRGPSGNkTLCNACGLYYKKHGgLKRPLSLKKDG 51
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
226-260 1.67e-13

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 64.65  E-value: 1.67e-13
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 17136408   226 CTNCGTRTTTLWRRNNDGEP-VCNACGLYYKLHGVN 260
Cdd:pfam00320   1 CSNCGTTKTPLWRRGPNGNRtLCNACGLYYKKKGLK 36
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
169-201 5.45e-12

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 60.02  E-value: 5.45e-12
                          10        20        30
                  ....*....|....*....|....*....|....
gi 17136408   169 CVNCGAISTPLWRRDGTGHY-LCNACGLYHKMNG 201
Cdd:pfam00320   1 CSNCGTTKTPLWRRGPNGNRtLCNACGLYYKKKG 34
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
171-338 1.87e-08

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 56.80  E-value: 1.87e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136408 171 NCGAISTPLWRR-DGTGHYLCNACGLYHKMNGMNRPLIKPSKrlvsaTATRRMGLCCTNCGTRTTTlwrRNNDGEPVCNA 249
Cdd:COG5641 303 LTTSTATPLWRRtSDKSSFSCNASGSALKPPGSKRPLLPKPD-----PNSKRSNATCMNCSSTPTN---KILSPPTTSNS 374
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136408 250 CGLYYKLHGVNRPLAMRKDGIQTRKRKPKKTGSGSAVGAGTGSGTGSTL-EAIKECKEEHDLKPSLSLERHSLSKLHTDm 328
Cdd:COG5641 375 PGAQVKLPNQTRSTGATKKKITRRRMNSGKIPALSSSMKNPVPKEFSPLiPQSTESETPSQSKSSLTSKLEEFESLSLL- 453
                       170
                ....*....|
gi 17136408 329 KSGTSSSSTL 338
Cdd:COG5641 454 KSVSSMMNLE 463
 
Name Accession Description Interval E-value
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
226-276 8.74e-23

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 91.28  E-value: 8.74e-23
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|...
gi 17136408 226 CTNCGTRTTTLWRRN-NDGEPVCNACGLYYKLHGVNRPLAMRK-DGIQTRKRK 276
Cdd:cd00202   2 CSNCGTTTTPLWRRGpSGGSTLCNACGLYWKKHGVMRPLSKRKkDQIKRRNRK 54
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
223-270 5.88e-19

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 80.54  E-value: 5.88e-19
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 17136408    223 GLCCTNCGTRTTTLWRRNNDGE-PVCNACGLYYKLHGV-NRPLAMRKDGI 270
Cdd:smart00401   3 GRSCSNCGTTETPLWRRGPSGNkTLCNACGLYYKKHGGlKRPLSLKKDGI 52
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
168-212 5.41e-18

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 77.80  E-value: 5.41e-18
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*.
gi 17136408 168 ECVNCGAISTPLWRRDG-TGHYLCNACGLYHKMNGMNRPLIKPSKR 212
Cdd:cd00202   1 ACSNCGTTTTPLWRRGPsGGSTLCNACGLYWKKHGVMRPLSKRKKD 46
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
164-212 8.29e-15

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 68.60  E-value: 8.29e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 17136408    164 GEGRECVNCGAISTPLWRRDGTGH-YLCNACGLYHKMNG-MNRPLIKPSKR 212
Cdd:smart00401   1 GSGRSCSNCGTTETPLWRRGPSGNkTLCNACGLYYKKHGgLKRPLSLKKDG 51
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
226-260 1.67e-13

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 64.65  E-value: 1.67e-13
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 17136408   226 CTNCGTRTTTLWRRNNDGEP-VCNACGLYYKLHGVN 260
Cdd:pfam00320   1 CSNCGTTKTPLWRRGPNGNRtLCNACGLYYKKKGLK 36
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
169-201 5.45e-12

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 60.02  E-value: 5.45e-12
                          10        20        30
                  ....*....|....*....|....*....|....
gi 17136408   169 CVNCGAISTPLWRRDGTGHY-LCNACGLYHKMNG 201
Cdd:pfam00320   1 CSNCGTTKTPLWRRGPNGNRtLCNACGLYYKKKG 34
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
171-338 1.87e-08

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 56.80  E-value: 1.87e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136408 171 NCGAISTPLWRR-DGTGHYLCNACGLYHKMNGMNRPLIKPSKrlvsaTATRRMGLCCTNCGTRTTTlwrRNNDGEPVCNA 249
Cdd:COG5641 303 LTTSTATPLWRRtSDKSSFSCNASGSALKPPGSKRPLLPKPD-----PNSKRSNATCMNCSSTPTN---KILSPPTTSNS 374
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136408 250 CGLYYKLHGVNRPLAMRKDGIQTRKRKPKKTGSGSAVGAGTGSGTGSTL-EAIKECKEEHDLKPSLSLERHSLSKLHTDm 328
Cdd:COG5641 375 PGAQVKLPNQTRSTGATKKKITRRRMNSGKIPALSSSMKNPVPKEFSPLiPQSTESETPSQSKSSLTSKLEEFESLSLL- 453
                       170
                ....*....|
gi 17136408 329 KSGTSSSSTL 338
Cdd:COG5641 454 KSVSSMMNLE 463
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
169-282 5.23e-08

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 55.26  E-value: 5.23e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136408 169 CVNCGAISTPLWRRD-----GTGHYLCNACGLYHKMNGMNRPLIK----------------------------------- 208
Cdd:COG5641 161 CSNCKTTSTPLWRRAssessLPGNNLCNACGLYLKLHGSPRAPISlksdsiksrssrsshnnndsngenantesignssa 240
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136408 209 -------------------------PSKRLVSATATRRMG-----------------LCCTNCG--TRTTTLWRRNNDGE 244
Cdd:COG5641 241 skltksweerpqgrqllsdagslspRSNNPKSPLLEGLMGstslqpvstpklvlpsdKKRSTLTtsTATPLWRRTSDKSS 320
                       170       180       190
                ....*....|....*....|....*....|....*...
gi 17136408 245 PVCNACGLYYKLHGVNRPLAMRKDGIQTRKRKPKKTGS 282
Cdd:COG5641 321 FSCNASGSALKPPGSKRPLLPKPDPNSKRSNATCMNCS 358
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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