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Conserved domains on  [gi|225703110|ref|NP_444402|]
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matrix extracellular phosphoglycoprotein precursor [Mus musculus]

Protein Classification

Osteoregulin domain-containing protein( domain architecture ID 10537541)

Osteoregulin domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Osteoregulin pfam07175
Osteoregulin; This family represents a conserved region approximately 180 residues long within ...
29-192 8.44e-85

Osteoregulin; This family represents a conserved region approximately 180 residues long within osteoregulin, a bone-remodelling protein expressed highly in osteocytes within trabecular and cortical bone. A conserved RGD motif is found towards the C-terminal end of this region, and this is potentially involved in integrin recognition.


:

Pssm-ID: 399867  Cd Length: 160  Bit Score: 256.70  E-value: 8.44e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225703110   29 NEDrSSCGNQDSIHKDLAASVYPDPTVDEGTEDGQGALLHPPGQDRYGAALLRNITQPVKSLVTGAELRREGNQEKRPQS 108
Cdd:pfam07175   1 NED-YSISNKENAHNDLKMSIYPESTGNNGAEDGDDAISKLHDQEEYGAALIRNNMQHIMEPVTVTELLGEENKENKPRN 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225703110  109 VLSVIPADVNDAKVSLKDIKNQESYLLTQSSPVKSKHTKHtrqTRRSTHYLTHLPQIKKTPSDLEGSGSPDLLVRGDNDV 188
Cdd:pfam07175  80 VLSKIPADVNYAKAHSKDKKNHQRDLQAQNSPVKSKSTHH---IQHNTDYLKQLPKVKKIPSDFEGSGYPDLQERGDNDI 156

                  ....
gi 225703110  189 PPFS 192
Cdd:pfam07175 157 SPFS 160
 
Name Accession Description Interval E-value
Osteoregulin pfam07175
Osteoregulin; This family represents a conserved region approximately 180 residues long within ...
29-192 8.44e-85

Osteoregulin; This family represents a conserved region approximately 180 residues long within osteoregulin, a bone-remodelling protein expressed highly in osteocytes within trabecular and cortical bone. A conserved RGD motif is found towards the C-terminal end of this region, and this is potentially involved in integrin recognition.


Pssm-ID: 399867  Cd Length: 160  Bit Score: 256.70  E-value: 8.44e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225703110   29 NEDrSSCGNQDSIHKDLAASVYPDPTVDEGTEDGQGALLHPPGQDRYGAALLRNITQPVKSLVTGAELRREGNQEKRPQS 108
Cdd:pfam07175   1 NED-YSISNKENAHNDLKMSIYPESTGNNGAEDGDDAISKLHDQEEYGAALIRNNMQHIMEPVTVTELLGEENKENKPRN 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225703110  109 VLSVIPADVNDAKVSLKDIKNQESYLLTQSSPVKSKHTKHtrqTRRSTHYLTHLPQIKKTPSDLEGSGSPDLLVRGDNDV 188
Cdd:pfam07175  80 VLSKIPADVNYAKAHSKDKKNHQRDLQAQNSPVKSKSTHH---IQHNTDYLKQLPKVKKIPSDFEGSGYPDLQERGDNDI 156

                  ....
gi 225703110  189 PPFS 192
Cdd:pfam07175 157 SPFS 160
 
Name Accession Description Interval E-value
Osteoregulin pfam07175
Osteoregulin; This family represents a conserved region approximately 180 residues long within ...
29-192 8.44e-85

Osteoregulin; This family represents a conserved region approximately 180 residues long within osteoregulin, a bone-remodelling protein expressed highly in osteocytes within trabecular and cortical bone. A conserved RGD motif is found towards the C-terminal end of this region, and this is potentially involved in integrin recognition.


Pssm-ID: 399867  Cd Length: 160  Bit Score: 256.70  E-value: 8.44e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225703110   29 NEDrSSCGNQDSIHKDLAASVYPDPTVDEGTEDGQGALLHPPGQDRYGAALLRNITQPVKSLVTGAELRREGNQEKRPQS 108
Cdd:pfam07175   1 NED-YSISNKENAHNDLKMSIYPESTGNNGAEDGDDAISKLHDQEEYGAALIRNNMQHIMEPVTVTELLGEENKENKPRN 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225703110  109 VLSVIPADVNDAKVSLKDIKNQESYLLTQSSPVKSKHTKHtrqTRRSTHYLTHLPQIKKTPSDLEGSGSPDLLVRGDNDV 188
Cdd:pfam07175  80 VLSKIPADVNYAKAHSKDKKNHQRDLQAQNSPVKSKSTHH---IQHNTDYLKQLPKVKKIPSDFEGSGYPDLQERGDNDI 156

                  ....
gi 225703110  189 PPFS 192
Cdd:pfam07175 157 SPFS 160
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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