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Conserved domains on  [gi|16130413|ref|NP_416983|]
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hydrogenase 4 component H [Escherichia coli str. K-12 substr. MG1655]

Protein Classification

PRK08222 family protein( domain architecture ID 11483168)

PRK08222 family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK08222 PRK08222
hydrogenase 4 subunit H; Validated
 1-181 7.83e-109

hydrogenase 4 subunit H; Validated


:

Pssm-ID: 181301 [Multi-domain]  Cd Length: 181  Bit Score: 308.22  E-value: 7.83e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130413    1 MLKLLKTIMRAGTATVKYPFAPLEVSPGFRGKPDLMPSQCIACGACACACPANALTIQTDDQQNSRTWQLYLGRCIYCGR 80
Cdd:PRK08222   1 MLKLLKTIMRAGTATVKYPFAPLEVSPGFRGKPDLMPSQCIACGACTCACPANALTIQTDDQQNSRTWQLYLGRCIYCGR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130413   81 CEEVCPTRAIQLTNNFELTVTNKADLYTRATFHLQRCSRCERPFAPQKTIALAAELLAQQQNAPQNREMLWAQASVCPEC 160
Cdd:PRK08222  81 CEEVCPTRAIQLTNNFELTVTNKADLYTRATFHLQRCSRCERPFAPQKTVALAAELLAQQQNAPQNREMLRAQASVCPEC 160

                        170       180
                 ....*....|....*....|.
gi 16130413  161 KQRATLINDDTDVLLVAKEQL 181
Cdd:PRK08222 161 KQRATLINDDTDVPLVAKEQL 181
 
Name Accession Description Interval E-value
PRK08222 PRK08222
hydrogenase 4 subunit H; Validated
 1-181 7.83e-109

hydrogenase 4 subunit H; Validated


Pssm-ID: 181301 [Multi-domain]  Cd Length: 181  Bit Score: 308.22  E-value: 7.83e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130413    1 MLKLLKTIMRAGTATVKYPFAPLEVSPGFRGKPDLMPSQCIACGACACACPANALTIQTDDQQNSRTWQLYLGRCIYCGR 80
Cdd:PRK08222   1 MLKLLKTIMRAGTATVKYPFAPLEVSPGFRGKPDLMPSQCIACGACTCACPANALTIQTDDQQNSRTWQLYLGRCIYCGR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130413   81 CEEVCPTRAIQLTNNFELTVTNKADLYTRATFHLQRCSRCERPFAPQKTIALAAELLAQQQNAPQNREMLWAQASVCPEC 160
Cdd:PRK08222  81 CEEVCPTRAIQLTNNFELTVTNKADLYTRATFHLQRCSRCERPFAPQKTVALAAELLAQQQNAPQNREMLRAQASVCPEC 160

                        170       180
                 ....*....|....*....|.
gi 16130413  161 KQRATLINDDTDVLLVAKEQL 181
Cdd:PRK08222 161 KQRATLINDDTDVPLVAKEQL 181
NuoI TIGR01971
NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of ...
 15-106 7.70e-13

NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of the NADH-quinone oxidoreductase complex I which generally couples NADH and ubiquinone oxidation/reduction in bacteria and mammalian mitochondria, but may act on NADPH and/or plastoquinone in cyanobacteria and plant chloroplasts. This model excludes "I" subunits from the closely related F420H2 dehydrogenase and formate hydrogenlyase complexes. [Energy metabolism, Electron transport]


Pssm-ID: 273902 [Multi-domain]  Cd Length: 122  Bit Score: 62.05  E-value: 7.70e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130413    15 TVKYPFAPLEVSPGFRGKPDLMPSQCIAC-----GACACACPANALTIQT----DDQQNSRTWQLYLGRCIYCGRCEEVC 85
Cdd:TIGR01971  15 TVQYPEEKLYLPPRFRGRIVLTRDPNGEEkcigcTLCAAVCPADAIRVVPaegeDGKRRLKFYEINFGRCIFCGLCEEAC 94

                          90       100
                  ....*....|....*....|.
gi 16130413    86 PTRAIQLTNNFELTVTNKADL 106
Cdd:TIGR01971  95 PTDAIVLTPEFELATYTRSDL 115
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 57-105 3.30e-10

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 53.60  E-value: 3.30e-10
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*....
gi 16130413  57 IQTDDQQNSRTWQLYLGRCIYCGRCEEVCPTRAIQLTnNFELTVTNKAD 105
Cdd:COG1143  19 ITIEDGEPGKVYVIDPDKCIGCGLCVEVCPTGAISMT-PFELAVEDREE 66
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 72-138 8.14e-06

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 43.15  E-value: 8.14e-06
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16130413  72 LGRCIYCGRCEEVCPTRAIQLTNNFELTV--TNKADLYTRAtfhLQRCSRCERPFaPQKTIALAAELLA 138
Cdd:cd10549  39 EDKCVFCGACVEVCPTGAIELTPEGKEYVpkEKEAEIDEEK---CIGCGLCVKVC-PVDAITLEDELEI 103
Fer4 pfam00037
4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to ...
 74-91 1.11e-04

4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 459642 [Multi-domain]  Cd Length: 24  Bit Score: 37.61  E-value: 1.11e-04
                          10
                  ....*....|....*...
gi 16130413    74 RCIYCGRCEEVCPTRAIQ 91
Cdd:pfam00037   7 KCIGCGACVEVCPVGAIT 24
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 74-95 2.04e-04

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 40.61  E-value: 2.04e-04
                         10        20
                 ....*....|....*....|..
gi 16130413   74 RCIYCGRCEEVCPTRAIQLTNN 95
Cdd:NF038196 186 KCIGCGICAKVCPVNNIEMEDG 207
 
Name Accession Description Interval E-value
PRK08222 PRK08222
hydrogenase 4 subunit H; Validated
 1-181 7.83e-109

hydrogenase 4 subunit H; Validated


Pssm-ID: 181301 [Multi-domain]  Cd Length: 181  Bit Score: 308.22  E-value: 7.83e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130413    1 MLKLLKTIMRAGTATVKYPFAPLEVSPGFRGKPDLMPSQCIACGACACACPANALTIQTDDQQNSRTWQLYLGRCIYCGR 80
Cdd:PRK08222   1 MLKLLKTIMRAGTATVKYPFAPLEVSPGFRGKPDLMPSQCIACGACTCACPANALTIQTDDQQNSRTWQLYLGRCIYCGR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130413   81 CEEVCPTRAIQLTNNFELTVTNKADLYTRATFHLQRCSRCERPFAPQKTIALAAELLAQQQNAPQNREMLWAQASVCPEC 160
Cdd:PRK08222  81 CEEVCPTRAIQLTNNFELTVTNKADLYTRATFHLQRCSRCERPFAPQKTVALAAELLAQQQNAPQNREMLRAQASVCPEC 160

                        170       180
                 ....*....|....*....|.
gi 16130413  161 KQRATLINDDTDVLLVAKEQL 181
Cdd:PRK08222 161 KQRATLINDDTDVPLVAKEQL 181
PRK12387 PRK12387
formate hydrogenlyase complex iron-sulfur subunit; Provisional
 1-171 2.53e-63

formate hydrogenlyase complex iron-sulfur subunit; Provisional


Pssm-ID: 183492 [Multi-domain]  Cd Length: 180  Bit Score: 192.94  E-value: 2.53e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130413    1 MLKLLKTIMRAGTATVKYPFAPLEVSPGFRGKPDLMPSQCIACGACACACPANALTIQTDDQQNSRTWQLYLGRCIYCGR 80
Cdd:PRK12387   1 MFKLIKKVIKTGTATSSYPLEPIAVDKNFRGKPEYNPQQCIGCAACVNACPSNALTVETDLATGELAWEFNLGRCIFCGR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130413   81 CEEVCPTRAIQLTNNFELTVTNKADLYTRATFHLQRCSRCERPFAPQKTIALAAELLaqQQNAPQNREMLWAQASVCPEC 160
Cdd:PRK12387  81 CEEVCPTAAIKLSQEFELAVWKKEDLLQQSEFALCNCRVCGRPFAVQKEIDYAIALL--KHNGDSRAENHRESFETCPEC 158

                        170
                 ....*....|.
gi 16130413  161 KQRATLINDDT 171
Cdd:PRK12387 159 KRQKCLVPSDR 169
PRK05888 PRK05888
NADH-quinone oxidoreductase subunit NuoI;
14-107 8.88e-18

NADH-quinone oxidoreductase subunit NuoI;


Pssm-ID: 235637 [Multi-domain]  Cd Length: 164  Bit Score: 76.07  E-value: 8.88e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130413   14 ATVKYPFAPLEVSPGFRG------KPDLM-------------PSQCiacgacacacpanaLTIQTDDQQNSR----TWQL 70
Cdd:PRK05888  29 VTIQYPEEKLPLSPRFRGrhalrrDPNGEerciacklcaaicPADA--------------ITIEAAEREDGRrrttRYDI 94

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 16130413   71 YLGRCIYCGRCEEVCPTRAIQLTNNFELTVTNKADLY 107
Cdd:PRK05888  95 NFGRCIFCGFCEEACPTDAIVETPDFELATETREELI 131
NuoI TIGR01971
NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of ...
 15-106 7.70e-13

NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of the NADH-quinone oxidoreductase complex I which generally couples NADH and ubiquinone oxidation/reduction in bacteria and mammalian mitochondria, but may act on NADPH and/or plastoquinone in cyanobacteria and plant chloroplasts. This model excludes "I" subunits from the closely related F420H2 dehydrogenase and formate hydrogenlyase complexes. [Energy metabolism, Electron transport]


Pssm-ID: 273902 [Multi-domain]  Cd Length: 122  Bit Score: 62.05  E-value: 7.70e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130413    15 TVKYPFAPLEVSPGFRGKPDLMPSQCIAC-----GACACACPANALTIQT----DDQQNSRTWQLYLGRCIYCGRCEEVC 85
Cdd:TIGR01971  15 TVQYPEEKLYLPPRFRGRIVLTRDPNGEEkcigcTLCAAVCPADAIRVVPaegeDGKRRLKFYEINFGRCIFCGLCEEAC 94

                          90       100
                  ....*....|....*....|.
gi 16130413    86 PTRAIQLTNNFELTVTNKADL 106
Cdd:TIGR01971  95 PTDAIVLTPEFELATYTRSDL 115
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 57-105 3.30e-10

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 53.60  E-value: 3.30e-10
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*....
gi 16130413  57 IQTDDQQNSRTWQLYLGRCIYCGRCEEVCPTRAIQLTnNFELTVTNKAD 105
Cdd:COG1143  19 ITIEDGEPGKVYVIDPDKCIGCGLCVEVCPTGAISMT-PFELAVEDREE 66
PRK08348 PRK08348
NADH-plastoquinone oxidoreductase subunit; Provisional
 70-105 1.04e-06

NADH-plastoquinone oxidoreductase subunit; Provisional


Pssm-ID: 181399 [Multi-domain]  Cd Length: 120  Bit Score: 45.60  E-value: 1.04e-06
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 16130413   70 LYLGRCIYCGRCEEVCPTRAIQLTNNFELTVTNKAD 105
Cdd:PRK08348  70 LWTGRCVFCGQCVDVCPTGALQMSDDFLLASYDRFD 105
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 72-138 8.14e-06

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 43.15  E-value: 8.14e-06
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16130413  72 LGRCIYCGRCEEVCPTRAIQLTNNFELTV--TNKADLYTRAtfhLQRCSRCERPFaPQKTIALAAELLA 138
Cdd:cd10549  39 EDKCVFCGACVEVCPTGAIELTPEGKEYVpkEKEAEIDEEK---CIGCGLCVKVC-PVDAITLEDELEI 103
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 74-100 2.78e-05

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 40.48  E-value: 2.78e-05
                        10        20
                ....*....|....*....|....*..
gi 16130413  74 RCIYCGRCEEVCPTRAIQLTNNFELTV 100
Cdd:COG1149  12 KCIGCGLCVEVCPEGAIKLDDGGAPVV 38
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 74-120 3.52e-05

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 40.03  E-value: 3.52e-05
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*..
gi 16130413  74 RCIYCGRCEEVCPTRAIQLTNNfeltvtnkadlytRATFHLQRCSRC 120
Cdd:COG2221  16 KCIGCGLCVAVCPTGAISLDDG-------------KLVIDEEKCIGC 49
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 74-100 3.78e-05

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 41.61  E-value: 3.78e-05
                        10        20
                ....*....|....*....|....*..
gi 16130413  74 RCIYCGRCEEVCPTRAIQLTNNFELTV 100
Cdd:cd10549  79 KCIGCGLCVKVCPVDAITLEDELEIVI 105
NapF COG1145
Ferredoxin [Energy production and conversion];
74-95 4.54e-05

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 42.40  E-value: 4.54e-05
                        10        20
                ....*....|....*....|..
gi 16130413  74 RCIYCGRCEEVCPTRAIQLTNN 95
Cdd:COG1145 183 KCIGCGLCVKVCPTGAIRLKDG 204
PRK13984 PRK13984
putative oxidoreductase; Provisional
 73-120 5.43e-05

putative oxidoreductase; Provisional


Pssm-ID: 172486 [Multi-domain]  Cd Length: 604  Bit Score: 42.83  E-value: 5.43e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 16130413   73 GRCIYCGRCEEVCPTRAIQLTNNFELTvTNKADLYTRATFHLQRCSRC 120
Cdd:PRK13984  45 EKCIGCGTCSKICPTDAITMVEVPDLP-QEYGKKPQRPVIDYGRCSFC 91
ndhI CHL00014
NADH dehydrogenase subunit I
 73-106 9.08e-05

NADH dehydrogenase subunit I


Pssm-ID: 214334 [Multi-domain]  Cd Length: 167  Bit Score: 40.90  E-value: 9.08e-05
                         10        20        30
                 ....*....|....*....|....*....|....
gi 16130413   73 GRCIYCGRCEEVCPTRAIQLTNNFELTVTNKADL 106
Cdd:CHL00014  99 GVCIFCGNCVEYCPTNCLSMTEEYELSTYDRHEL 132
Fer4 pfam00037
4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to ...
 74-91 1.11e-04

4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 459642 [Multi-domain]  Cd Length: 24  Bit Score: 37.61  E-value: 1.11e-04
                          10
                  ....*....|....*...
gi 16130413    74 RCIYCGRCEEVCPTRAIQ 91
Cdd:pfam00037   7 KCIGCGACVEVCPVGAIT 24
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 74-95 2.04e-04

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 40.61  E-value: 2.04e-04
                         10        20
                 ....*....|....*....|..
gi 16130413   74 RCIYCGRCEEVCPTRAIQLTNN 95
Cdd:NF038196 186 KCIGCGICAKVCPVNNIEMEDG 207
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
74-97 2.46e-04

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 38.17  E-value: 2.46e-04
                        10        20
                ....*....|....*....|....
gi 16130413  74 RCIYCGRCEEVCPTRAIQLTNNFE 97
Cdd:COG2768  41 KCIGCGACIEVCPVGAIKIEWEED 64
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
74-97 4.40e-04

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 40.01  E-value: 4.40e-04
                        10        20
                ....*....|....*....|....
gi 16130413  74 RCIYCGRCEEVCPTRAIQLTNNFE 97
Cdd:COG4624 121 KCISCGQCVAVCPFGAITEKSDIE 144
sulfite_red_A TIGR02910
sulfite reductase, subunit A; Members of this protein family include the A subunit, one of ...
 64-87 5.70e-04

sulfite reductase, subunit A; Members of this protein family include the A subunit, one of three subunits, of the anaerobic sulfite reductase of Salmonella, and close homologs from various Clostridum species, where the three-gene neighborhood is preserved. Two such gene clusters are found in Clostridium perfringens, but it may be that these sets of genes correspond to the distinct assimilatory and dissimilatory forms as seen in Clostridium pasteurianum. Note that any one of these enzymes may have secondary substates such as NH2OH, SeO3(2-), and SO3(2-). Heterologous expression of the anaerobic sulfite reductase of Salmonella confers on Escherichia coli the ability to produce hydrogen sulfide gas from sulfite. [Central intermediary metabolism, Sulfur metabolism]


Pssm-ID: 131956  Cd Length: 334  Bit Score: 39.43  E-value: 5.70e-04
                          10        20
                  ....*....|....*....|....
gi 16130413    64 NSRTWQLYLGRCIYCGRCEEVCPT 87
Cdd:TIGR02910 211 RSDFWDEYDSRCIACGRCNTVCPT 234
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 74-93 7.60e-04

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 37.76  E-value: 7.60e-04
                        10        20
                ....*....|....*....|
gi 16130413  74 RCIYCGRCEEVCPTRAIQLT 93
Cdd:cd10549 109 KCIGCGICAEVCPVNAIKLV 128
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 74-90 8.26e-04

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 36.57  E-value: 8.26e-04
                        10
                ....*....|....*..
gi 16130413  74 RCIYCGRCEEVCPTRAI 90
Cdd:COG2221  45 KCIGCGACIRVCPTGAI 61
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 72-92 9.67e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 38.01  E-value: 9.67e-04
                        10        20
                ....*....|....*....|.
gi 16130413  72 LGRCIYCGRCEEVCPTRAIQL 92
Cdd:cd16373  13 LALCIRCGLCVEACPTGVIQP 33
NapF COG1145
Ferredoxin [Energy production and conversion];
73-95 1.07e-03

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 38.55  E-value: 1.07e-03
                        10        20
                ....*....|....*....|...
gi 16130413  73 GRCIYCGRCEEVCPTRAIQLTNN 95
Cdd:COG1145 213 DKCIGCGACVKVCPVGAISLEPK 235
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 75-90 1.70e-03

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 35.46  E-value: 1.70e-03
                        10
                ....*....|....*.
gi 16130413  75 CIYCGRCEEVCPTRAI 90
Cdd:COG1146  42 CIGCGACELVCPVGAI 57
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 64-92 1.96e-03

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 35.47  E-value: 1.96e-03
                        10        20
                ....*....|....*....|....*....
gi 16130413  64 NSRTWQLYLGRCIYCGRCEEVCPTRAIQL 92
Cdd:COG1149  32 DGGAPVVDPDLCTGCGACVGVCPTGAITL 60
HycB COG1142
Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];
74-106 2.92e-03

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];


Pssm-ID: 440757 [Multi-domain]  Cd Length: 138  Bit Score: 36.17  E-value: 2.92e-03
                        10        20        30
                ....*....|....*....|....*....|...
gi 16130413  74 RCIYCGRCEEVCPTRAIQLTNNFELTVTNKADL 106
Cdd:COG1142  82 KCIGCGLCVLACPFGAITMVGEKSRAVAVKCDL 114
NapH COG0348
Polyferredoxin NapH [Energy production and conversion];
75-97 3.33e-03

Polyferredoxin NapH [Energy production and conversion];


Pssm-ID: 440117 [Multi-domain]  Cd Length: 263  Bit Score: 36.96  E-value: 3.33e-03
                        10        20
                ....*....|....*....|...
gi 16130413  75 CIYCGRCEEVCPTRAIQLTNNFE 97
Cdd:COG0348 238 CINCGRCIDACPKDAIRFSSRGE 260
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 74-92 4.85e-03

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 34.63  E-value: 4.85e-03
                        10
                ....*....|....*....
gi 16130413  74 RCIYCGRCEEVCPTRAIQL 92
Cdd:COG4231  52 LCIGCGSCVQVCPVDAIKL 70
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 74-95 7.68e-03

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 33.53  E-value: 7.68e-03
                        10        20
                ....*....|....*....|..
gi 16130413  74 RCIYCGRCEEVCPTRAIQLTNN 95
Cdd:COG1146   9 KCIGCGACVEVCPVDVLELDEE 30
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 66-89 8.44e-03

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 33.27  E-value: 8.44e-03
                          10        20
                  ....*....|....*....|....
gi 16130413    66 RTWQLYLGRCIYCGRCEEVCPTRA 89
Cdd:pfam12838  28 KTVVIDPERCVGCGACVAVCPTGA 51
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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