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Conserved domains on  [gi|90111358|ref|NP_416457|]
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flagellar biosynthesis protein FliO [Escherichia coli str. K-12 substr. MG1655]

Protein Classification

flagellar type III secretion system protein FliO( domain architecture ID 10013815)

flagellar type III secretion system protein FliO is an essential component of the flagellum-specific protein export apparatus

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK11486 PRK11486
flagellar type III secretion system protein FliO;
1-121 6.65e-46

flagellar type III secretion system protein FliO;


:

Pssm-ID: 183160  Cd Length: 124  Bit Score: 144.59  E-value: 6.65e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111358    1 MNNHATVQSSAPVSAAPLLQVSGALIAIIALILAAAWLVKRLGFAPKRTGVNGLKISASASLGARERVVVVDVEDARLVL 80
Cdd:PRK11486   1 MNNHATVQSSAPVSGSPLLQVSGALIGIIALILAAAWLVKRLGFAPKRTGVRGLKISASASLGARERVVIVDVEDARLVL 80
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 90111358   81 GVTAGQINLLHKLPPSAPTEE---IPQTDFQSVMKNLLKRSGRS 121
Cdd:PRK11486  81 GVTAGQINLLHKLPPAAPTEEapvIPQADFQSVMKNLLKRSGRS 124
 
Name Accession Description Interval E-value
PRK11486 PRK11486
flagellar type III secretion system protein FliO;
1-121 6.65e-46

flagellar type III secretion system protein FliO;


Pssm-ID: 183160  Cd Length: 124  Bit Score: 144.59  E-value: 6.65e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111358    1 MNNHATVQSSAPVSAAPLLQVSGALIAIIALILAAAWLVKRLGFAPKRTGVNGLKISASASLGARERVVVVDVEDARLVL 80
Cdd:PRK11486   1 MNNHATVQSSAPVSGSPLLQVSGALIGIIALILAAAWLVKRLGFAPKRTGVRGLKISASASLGARERVVIVDVEDARLVL 80
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 90111358   81 GVTAGQINLLHKLPPSAPTEE---IPQTDFQSVMKNLLKRSGRS 121
Cdd:PRK11486  81 GVTAGQINLLHKLPPAAPTEEapvIPQADFQSVMKNLLKRSGRS 124
FliO COG3190
Flagellar biogenesis protein FliO [Cell motility];
1-117 4.26e-14

Flagellar biogenesis protein FliO [Cell motility];


Pssm-ID: 442423  Cd Length: 122  Bit Score: 63.46  E-value: 4.26e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111358   1 MNNHATVQSSAPVSAAPLLQVSGALIAIIALILAAAWLVKRLGfaPKRTGVNGLKISASASLGARERVVVVDVEDARLVL 80
Cdd:COG3190   1 MKRLAAAAAPAPSSGGSLLQVLLALLLVLALILGLAWLLRRLG--GRGGGGGALRVVASLSLGPRERLVLVEVGGRQLLL 78
                        90       100       110       120
                ....*....|....*....|....*....|....*....|.
gi 90111358  81 GVTAGQINLLHKLPPSAPTEEIPQT----DFQSVMKNLLKR 117
Cdd:COG3190  79 GVTPQQITLLHELPAPEEAEELEAApappSFAQLLKRALKR 119
FliO pfam04347
Flagellar biosynthesis protein, FliO; FliO is an essential component of the flagellum-specific ...
37-115 1.45e-08

Flagellar biosynthesis protein, FliO; FliO is an essential component of the flagellum-specific protein export apparatus. It is an integral membrane protein that acts as an assembly chaperone for the flagellar protein FliP (pfam00813). It is crucial, although not strictly required, for efficient FliP assembly and, thus flagellar assembly and function.


Pssm-ID: 427883  Cd Length: 87  Bit Score: 48.45  E-value: 1.45e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111358    37 WLVKRLGFAPKRTGVNG--LKISASASLGARERVVVVDVEDARLVLGVTAGQINLLHKLPPSAPTEEIPQTD------FQ 108
Cdd:pfam04347   1 WLLRRFGGGGQGGALGGpnLKVLASLPLGPRERLVLVEVGERQLLLGVTPGSITLLHELDDEELPEPEELAAasapagFA 80

                  ....*..
gi 90111358   109 SVMKNLL 115
Cdd:pfam04347  81 QLLKKAL 87
FliO_TIGR TIGR03500
flagellar biosynthetic protein FliO; This short protein found in flagellar biosynthesis ...
37-92 2.11e-05

flagellar biosynthetic protein FliO; This short protein found in flagellar biosynthesis operons contains a highly hydrophobic N-terminal sequence followed generally by two basic amino acids. This region is reminiscent of but distinct from the twin-arginine translocation signal sequence. Some instances of this gene have been names "FliZ" but phylogenetic tree building supports a single FliO family.


Pssm-ID: 274610  Cd Length: 69  Bit Score: 39.37  E-value: 2.11e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 90111358    37 WLVKRLGFA-PKRTGVNGLKISASASLGARERVVVVDVEDARLVLGVTAGQINLLHK 92
Cdd:TIGR03500  13 WLLRRFGSAgLNGQGGKGLKVLESLPLGPKESLVLVEVGDRQLLLGVTDGGITLLKE 69
 
Name Accession Description Interval E-value
PRK11486 PRK11486
flagellar type III secretion system protein FliO;
1-121 6.65e-46

flagellar type III secretion system protein FliO;


Pssm-ID: 183160  Cd Length: 124  Bit Score: 144.59  E-value: 6.65e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111358    1 MNNHATVQSSAPVSAAPLLQVSGALIAIIALILAAAWLVKRLGFAPKRTGVNGLKISASASLGARERVVVVDVEDARLVL 80
Cdd:PRK11486   1 MNNHATVQSSAPVSGSPLLQVSGALIGIIALILAAAWLVKRLGFAPKRTGVRGLKISASASLGARERVVIVDVEDARLVL 80
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 90111358   81 GVTAGQINLLHKLPPSAPTEE---IPQTDFQSVMKNLLKRSGRS 121
Cdd:PRK11486  81 GVTAGQINLLHKLPPAAPTEEapvIPQADFQSVMKNLLKRSGRS 124
FliO COG3190
Flagellar biogenesis protein FliO [Cell motility];
1-117 4.26e-14

Flagellar biogenesis protein FliO [Cell motility];


Pssm-ID: 442423  Cd Length: 122  Bit Score: 63.46  E-value: 4.26e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111358   1 MNNHATVQSSAPVSAAPLLQVSGALIAIIALILAAAWLVKRLGfaPKRTGVNGLKISASASLGARERVVVVDVEDARLVL 80
Cdd:COG3190   1 MKRLAAAAAPAPSSGGSLLQVLLALLLVLALILGLAWLLRRLG--GRGGGGGALRVVASLSLGPRERLVLVEVGGRQLLL 78
                        90       100       110       120
                ....*....|....*....|....*....|....*....|.
gi 90111358  81 GVTAGQINLLHKLPPSAPTEEIPQT----DFQSVMKNLLKR 117
Cdd:COG3190  79 GVTPQQITLLHELPAPEEAEELEAApappSFAQLLKRALKR 119
FliO pfam04347
Flagellar biosynthesis protein, FliO; FliO is an essential component of the flagellum-specific ...
37-115 1.45e-08

Flagellar biosynthesis protein, FliO; FliO is an essential component of the flagellum-specific protein export apparatus. It is an integral membrane protein that acts as an assembly chaperone for the flagellar protein FliP (pfam00813). It is crucial, although not strictly required, for efficient FliP assembly and, thus flagellar assembly and function.


Pssm-ID: 427883  Cd Length: 87  Bit Score: 48.45  E-value: 1.45e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111358    37 WLVKRLGFAPKRTGVNG--LKISASASLGARERVVVVDVEDARLVLGVTAGQINLLHKLPPSAPTEEIPQTD------FQ 108
Cdd:pfam04347   1 WLLRRFGGGGQGGALGGpnLKVLASLPLGPRERLVLVEVGERQLLLGVTPGSITLLHELDDEELPEPEELAAasapagFA 80

                  ....*..
gi 90111358   109 SVMKNLL 115
Cdd:pfam04347  81 QLLKKAL 87
FliO_TIGR TIGR03500
flagellar biosynthetic protein FliO; This short protein found in flagellar biosynthesis ...
37-92 2.11e-05

flagellar biosynthetic protein FliO; This short protein found in flagellar biosynthesis operons contains a highly hydrophobic N-terminal sequence followed generally by two basic amino acids. This region is reminiscent of but distinct from the twin-arginine translocation signal sequence. Some instances of this gene have been names "FliZ" but phylogenetic tree building supports a single FliO family.


Pssm-ID: 274610  Cd Length: 69  Bit Score: 39.37  E-value: 2.11e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 90111358    37 WLVKRLGFA-PKRTGVNGLKISASASLGARERVVVVDVEDARLVLGVTAGQINLLHK 92
Cdd:TIGR03500  13 WLLRRFGSAgLNGQGGKGLKVLESLPLGPKESLVLVEVGDRQLLLGVTDGGITLLKE 69
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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