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Conserved domains on  [gi|15833374|ref|NP_312147|]
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septum formation inhibitor [Escherichia coli O157:H7 str. Sakai]

Protein Classification

Maf family protein( domain architecture ID 10785471)

multicopy associated filamentation (Maf) family protein is involved in septum formation and also has a role as a house-cleaning NTP pyrophosphatase

CATH:  3.90.950.10
EC:  3.6.1.-
Gene Ontology:  GO:0009117|GO:0047429|GO:0009146|GO:0000166
PubMed:  24210219
SCOP:  4000520

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Maf COG0424
7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary ...
 4-185 3.03e-99

7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary metabolites biosynthesis, transport and catabolism];


:

Pssm-ID: 440193  Cd Length: 189  Bit Score: 285.01  E-value: 3.03e-99
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374   4 LYLASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQYVVRLAREKARAgVAQTAKDLPVLGADTIVILNGEVLEKP 83
Cdd:COG0424   3 LILASASPRRRELLEQLGLPFEVVPPDIDETPLPGESPEELVLRLARAKAEA-VAARLPDALVLGADTVVVLDGRILGKP 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374  84 RDAEHAAQMLRKLSGQTHQVMTAVALADSR-HILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCFVRK 162
Cdd:COG0424  82 ADAEEARAMLRRLSGRTHRVHTGVALIDPGgRLWTRVVTTRVTFRPLSDAEIEAYLATGEPLDKAGAYGIQGLGAALVER 161

                       170       180
                ....*....|....*....|...
gi 15833374 163 INGSYQAVVGLPLVETYELLSNF 185
Cdd:COG0424 162 IEGSYSNVVGLPLIELLELLREL 184
 
Name Accession Description Interval E-value
Maf COG0424
7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary ...
 4-185 3.03e-99

7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440193  Cd Length: 189  Bit Score: 285.01  E-value: 3.03e-99
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374   4 LYLASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQYVVRLAREKARAgVAQTAKDLPVLGADTIVILNGEVLEKP 83
Cdd:COG0424   3 LILASASPRRRELLEQLGLPFEVVPPDIDETPLPGESPEELVLRLARAKAEA-VAARLPDALVLGADTVVVLDGRILGKP 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374  84 RDAEHAAQMLRKLSGQTHQVMTAVALADSR-HILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCFVRK 162
Cdd:COG0424  82 ADAEEARAMLRRLSGRTHRVHTGVALIDPGgRLWTRVVTTRVTFRPLSDAEIEAYLATGEPLDKAGAYGIQGLGAALVER 161

                       170       180
                ....*....|....*....|...
gi 15833374 163 INGSYQAVVGLPLVETYELLSNF 185
Cdd:COG0424 162 IEGSYSNVVGLPLIELLELLREL 184
maf TIGR00172
MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A ...
 1-183 6.54e-96

MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A member of the family is found in the Archaeon Pyrococcus horikoshii and another in the round worm Caenorhabditis elegans. [Cellular processes, Cell division]


Pssm-ID: 129276  Cd Length: 183  Bit Score: 276.59  E-value: 6.54e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374     1 MTS-LYLASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQYVVRLAREKARAgVAQTAKDLPVLGADTIVILNGEV 79
Cdd:TIGR00172   1 MTKeLILASQSPRRKELLEELGISFEQIVSEFDEKSLKTTSPRELVYRLAKEKAQA-VAELLADALIIGADTVVILDGEI 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374    80 LEKPRDAEHAAQMLRKLSGQTHQVMTAVALADSRHILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCF 159
Cdd:TIGR00172  80 YGKPKDKEEAAEFLRKLSGQEHEVYTAVALIDSVHLLTFLDVTKVHFRALDPEEIEKYVESGEPLEKAGAFGIEGFGAPL 159

                         170       180
                  ....*....|....*....|....
gi 15833374   160 VRKINGSYQAVVGLPLVETYELLS 183
Cdd:TIGR00172 160 IKKIDGDYSNVVGLPLEKLLGALR 183
Maf cd00555
Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in ...
 4-182 2.35e-93

Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or nucleic acid-binding protein with structural similarity to the hypoxanthine/xanthine NTP pyrophosphatase Ham1 from Methanococcus jannaschii, RNase H from Escherichia coli, and some other nucleotide or RNA-binding proteins.


Pssm-ID: 238310  Cd Length: 180  Bit Score: 269.73  E-value: 2.35e-93
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374   4 LYLASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQYVVRLAREKARAGVAQTAKDLPVLGADTIVILNGEVLEKP 83
Cdd:cd00555   1 LILASASPRRRELLEQLGIPFEVVPSDIDETPIKGESPEDYVLRLAEAKAEAVAARLPPDALVIGADTVVVLDGRILGKP 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374  84 RDAEHAAQMLRKLSGQTHQVMTAVALAD-SRHILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCFVRK 162
Cdd:cd00555  81 KDREEAREMLKRLSGRTHEVYTGVALIDpGGKLVTDVESTKVRFRELSDEEIEAYVASGEPLDKAGAYGIQGLGGALIER 160

                       170       180
                ....*....|....*....|
gi 15833374 163 INGSYQAVVGLPLVETYELL 182
Cdd:cd00555 161 IEGDYSNVVGLPLPELLKLL 180
Maf pfam02545
Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and ...
 4-185 3.24e-85

Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and archaea.


Pssm-ID: 460586  Cd Length: 174  Bit Score: 248.86  E-value: 3.24e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374     4 LYLASGSPRRQELLAQLGVTFERIVTGIEEQRQP-QESAQQYVVRLAREKARAGVaqtakdlpvLGADTIVILngeVLEK 82
Cdd:pfam02545   1 LILASASPRRRELLEQLGIEFEVVPSDIDETPLKeDPAPEEYVLRLARAKAEALV---------IGADTVVVL---ILGK 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374    83 PRDAEHAAQMLRKLSGQTHQVMTAVALADSRH---ILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCF 159
Cdd:pfam02545  69 PKDEEEARAMLKRLSGRTHEVYTGVALINPGGgtgGVSFVETTRVTFRPLSDEEIEAYVATGEPLDKAGAYGIQGLGAAL 148

                         170       180
                  ....*....|....*....|....*.
gi 15833374   160 VRKINGSYQAVVGLPLVETYELLSNF 185
Cdd:pfam02545 149 VERIEGDYSNVVGLPLIELLRLLREL 174
PRK00648 PRK00648
Maf-like protein; Reviewed
 1-186 4.97e-69

Maf-like protein; Reviewed


Pssm-ID: 234807  Cd Length: 191  Bit Score: 208.61  E-value: 4.97e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374    1 MTSLYLASGSPRRQELLAQLGVTFERIVT-GIEEQRQPQESAQQYVVRLAREKARAGVAQTAKDLPVLGADTIVILNGEV 79
Cdd:PRK00648   2 KYKIILASSSPRRKEILEGFRIPFEVVPSpFVEESYPYSLDPEEITLELARLKAEAVRSDLFPDELIITADTIVWYDGKV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374   80 LEKPRDAEHAAQMLRKLSGQTHQVMTAVALADSRHILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCF 159
Cdd:PRK00648  82 LGKPKDEEEAVEMLRTLSGKTHEVITGVCLLHNGKLLSGSETTQVTFRELSDEEIEYYIDTYKPLDKAGAYGIQEWGGLI 161

                        170       180
                 ....*....|....*....|....*..
gi 15833374  160 VRKINGSYQAVVGLPLVETYELLSNFN 186
Cdd:PRK00648 162 VKKIEGSYYNVMGLPIQTLYEELKELG 188
 
Name Accession Description Interval E-value
Maf COG0424
7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary ...
 4-185 3.03e-99

7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440193  Cd Length: 189  Bit Score: 285.01  E-value: 3.03e-99
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374   4 LYLASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQYVVRLAREKARAgVAQTAKDLPVLGADTIVILNGEVLEKP 83
Cdd:COG0424   3 LILASASPRRRELLEQLGLPFEVVPPDIDETPLPGESPEELVLRLARAKAEA-VAARLPDALVLGADTVVVLDGRILGKP 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374  84 RDAEHAAQMLRKLSGQTHQVMTAVALADSR-HILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCFVRK 162
Cdd:COG0424  82 ADAEEARAMLRRLSGRTHRVHTGVALIDPGgRLWTRVVTTRVTFRPLSDAEIEAYLATGEPLDKAGAYGIQGLGAALVER 161

                       170       180
                ....*....|....*....|...
gi 15833374 163 INGSYQAVVGLPLVETYELLSNF 185
Cdd:COG0424 162 IEGSYSNVVGLPLIELLELLREL 184
maf TIGR00172
MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A ...
 1-183 6.54e-96

MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A member of the family is found in the Archaeon Pyrococcus horikoshii and another in the round worm Caenorhabditis elegans. [Cellular processes, Cell division]


Pssm-ID: 129276  Cd Length: 183  Bit Score: 276.59  E-value: 6.54e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374     1 MTS-LYLASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQYVVRLAREKARAgVAQTAKDLPVLGADTIVILNGEV 79
Cdd:TIGR00172   1 MTKeLILASQSPRRKELLEELGISFEQIVSEFDEKSLKTTSPRELVYRLAKEKAQA-VAELLADALIIGADTVVILDGEI 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374    80 LEKPRDAEHAAQMLRKLSGQTHQVMTAVALADSRHILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCF 159
Cdd:TIGR00172  80 YGKPKDKEEAAEFLRKLSGQEHEVYTAVALIDSVHLLTFLDVTKVHFRALDPEEIEKYVESGEPLEKAGAFGIEGFGAPL 159

                         170       180
                  ....*....|....*....|....
gi 15833374   160 VRKINGSYQAVVGLPLVETYELLS 183
Cdd:TIGR00172 160 IKKIDGDYSNVVGLPLEKLLGALR 183
Maf cd00555
Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in ...
 4-182 2.35e-93

Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or nucleic acid-binding protein with structural similarity to the hypoxanthine/xanthine NTP pyrophosphatase Ham1 from Methanococcus jannaschii, RNase H from Escherichia coli, and some other nucleotide or RNA-binding proteins.


Pssm-ID: 238310  Cd Length: 180  Bit Score: 269.73  E-value: 2.35e-93
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374   4 LYLASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQYVVRLAREKARAGVAQTAKDLPVLGADTIVILNGEVLEKP 83
Cdd:cd00555   1 LILASASPRRRELLEQLGIPFEVVPSDIDETPIKGESPEDYVLRLAEAKAEAVAARLPPDALVIGADTVVVLDGRILGKP 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374  84 RDAEHAAQMLRKLSGQTHQVMTAVALAD-SRHILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCFVRK 162
Cdd:cd00555  81 KDREEAREMLKRLSGRTHEVYTGVALIDpGGKLVTDVESTKVRFRELSDEEIEAYVASGEPLDKAGAYGIQGLGGALIER 160

                       170       180
                ....*....|....*....|
gi 15833374 163 INGSYQAVVGLPLVETYELL 182
Cdd:cd00555 161 IEGDYSNVVGLPLPELLKLL 180
Maf pfam02545
Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and ...
 4-185 3.24e-85

Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and archaea.


Pssm-ID: 460586  Cd Length: 174  Bit Score: 248.86  E-value: 3.24e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374     4 LYLASGSPRRQELLAQLGVTFERIVTGIEEQRQP-QESAQQYVVRLAREKARAGVaqtakdlpvLGADTIVILngeVLEK 82
Cdd:pfam02545   1 LILASASPRRRELLEQLGIEFEVVPSDIDETPLKeDPAPEEYVLRLARAKAEALV---------IGADTVVVL---ILGK 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374    83 PRDAEHAAQMLRKLSGQTHQVMTAVALADSRH---ILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCF 159
Cdd:pfam02545  69 PKDEEEARAMLKRLSGRTHEVYTGVALINPGGgtgGVSFVETTRVTFRPLSDEEIEAYVATGEPLDKAGAYGIQGLGAAL 148

                         170       180
                  ....*....|....*....|....*.
gi 15833374   160 VRKINGSYQAVVGLPLVETYELLSNF 185
Cdd:pfam02545 149 VERIEGDYSNVVGLPLIELLRLLREL 174
PRK00648 PRK00648
Maf-like protein; Reviewed
 1-186 4.97e-69

Maf-like protein; Reviewed


Pssm-ID: 234807  Cd Length: 191  Bit Score: 208.61  E-value: 4.97e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374    1 MTSLYLASGSPRRQELLAQLGVTFERIVT-GIEEQRQPQESAQQYVVRLAREKARAGVAQTAKDLPVLGADTIVILNGEV 79
Cdd:PRK00648   2 KYKIILASSSPRRKEILEGFRIPFEVVPSpFVEESYPYSLDPEEITLELARLKAEAVRSDLFPDELIITADTIVWYDGKV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374   80 LEKPRDAEHAAQMLRKLSGQTHQVMTAVALADSRHILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCF 159
Cdd:PRK00648  82 LGKPKDEEEAVEMLRTLSGKTHEVITGVCLLHNGKLLSGSETTQVTFRELSDEEIEYYIDTYKPLDKAGAYGIQEWGGLI 161

                        170       180
                 ....*....|....*....|....*..
gi 15833374  160 VRKINGSYQAVVGLPLVETYELLSNFN 186
Cdd:PRK00648 162 VKKIEGSYYNVMGLPIQTLYEELKELG 188
PRK14368 PRK14368
Maf-like protein; Provisional
 6-188 6.69e-62

Maf-like protein; Provisional


Pssm-ID: 237693  Cd Length: 193  Bit Score: 190.76  E-value: 6.69e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374    6 LASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQYVVRLAREKARAGVAQTAKDLpVLGADTIVILNGEVLEKPRD 85
Cdd:PRK14368   9 LASASPRRSELLASAGIEFDVVPADIPEEPLPGEEPVDHVLRLAREKARAAAALAEGRF-FIGADTIVVCDGEIMGKPKD 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374   86 AEHAAQMLRKLSGQTHQVMTAVALAD--SRHILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCFVRKI 163
Cdd:PRK14368  88 EADAVRMLKKLSGVPHEVITGFAVYDreRDGCVTKAVRTKVFFKPLRDEEIRDYIATGCPMDKAGAYAIQGGAAHMVRKI 167

                        170       180
                 ....*....|....*....|....*
gi 15833374  164 NGSYQAVVGLPLVETYELLSNFNAL 188
Cdd:PRK14368 168 DGSYTNVVGLPLCEVVEALRTIGAL 192
PRK04694 PRK04694
Maf-like protein; Reviewed
 4-187 2.55e-61

Maf-like protein; Reviewed


Pssm-ID: 179873  Cd Length: 190  Bit Score: 189.02  E-value: 2.55e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374    4 LYLASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQYVVRLAREKARAGVAQTAKDLP---VLGADTIVILNGEVL 80
Cdd:PRK04694   2 LYLASRSPRRRELLQRLDVPFQTLQLDVPEVRAADESPDHYVQRVALEKAHAGLALVQAADAdaiVLGSDTEVVLGERVF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374   81 EKPRDAEHAAQMLRKLSGQTHQVMTAVAL-ADSRHILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCF 159
Cdd:PRK04694  82 GKPVDVDDAIAMLRALSGRTHQVLTAVVLvCAQRAPAQALVVSEVTFDLLDDAQIAAYAASGEPMGKAGAYAIQGRAERF 161

                        170       180
                 ....*....|....*....|....*...
gi 15833374  160 VRKINGSYQAVVGLPLVETYELLSNFNA 187
Cdd:PRK04694 162 IRHLSGSYSGVMGLPLYQTSQLLTAFGA 189
PRK00078 PRK00078
Maf-like protein; Reviewed
 6-184 2.33e-59

Maf-like protein; Reviewed


Pssm-ID: 234618  Cd Length: 192  Bit Score: 184.16  E-value: 2.33e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374    6 LASGSPRRQELLAQLGVTFERIVTGIEEQRQP-QESAQQYVVRLAREKARAgVAQTAKDLP--VLGADTIVILNGEVLEK 82
Cdd:PRK00078   5 LASASERRQELLKRILEDFQVIVSDFDESSVPfKGNIESYVMNLAEGKARS-VSKKLDQESsiVIGCDTIVAFNGKVLGK 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374   83 PRDAEHAAQMLRKLSGQTHQVMTAVALAD--SRHILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCFV 160
Cdd:PRK00078  84 PKDEEDAFEMLKALSGNEHEVYSGIAILDtkSNKIIKDFVCTEVKFSKLTDRQIRKYINTGEPMDKAGAYGIQGKGGVFV 163

                        170       180
                 ....*....|....*....|....
gi 15833374  161 RKINGSYQAVVGLPLVETYELLSN 184
Cdd:PRK00078 164 EEINGCYYNVVGLPLNKLYKMLEE 187
PRK14364 PRK14364
Maf-like protein; Provisional
 6-182 6.73e-57

Maf-like protein; Provisional


Pssm-ID: 184648  Cd Length: 181  Bit Score: 177.50  E-value: 6.73e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374    6 LASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQYVVRLAREKARAgVAQTAKDLPVLGADTIVILNGEVLEKPRD 85
Cdd:PRK14364   1 LASSSPRRRELLQQLGLNFEIYSPDIDESVHEGELVHQYVERLAREKAQA-VLNIFPDSVIIAADTSLGLDGQIIGKPDS 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374   86 AEHAAQMLRKLSGQTHQVMTAVALADSRHILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCFVRKING 165
Cdd:PRK14364  80 KQHAFDIWKQLSGRWHDVFSGICIATQQQILSQVVQTQVEFASLTTQDMEDYWATGEPVGKAGAYAIQGIASQYIPKIQG 159

                        170
                 ....*....|....*..
gi 15833374  166 SYQAVVGLPLVETYELL 182
Cdd:PRK14364 160 SYSNVVGLPLYEFSQLF 176
PRK14367 PRK14367
Maf-like protein; Provisional
 1-185 3.27e-51

Maf-like protein; Provisional


Pssm-ID: 237692  Cd Length: 202  Bit Score: 163.70  E-value: 3.27e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374    1 MTSLYLASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQYVVRLAREKARAGVA------QTAKDLPVLGADTIVI 74
Cdd:PRK14367   1 MNTLYLGSNSPRRMEILTQLGYRVVKLPAGIDETVKAGETPARYVQRMAEEKNRTALTlfcetnGTMPDFPLITADTCVV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374   75 LNGEVLEKPRDAEHAAQMLRKLSGQTHQVMTAVALADSRHILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQG 154
Cdd:PRK14367  81 SDGIILGKPRSQAEAIEFLNRLSGKQHTVLTAVCIHYRGKTSSRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYAVQG 160

                        170       180       190
                 ....*....|....*....|....*....|.
gi 15833374  155 LGGCFVRKINGSYQAVVGLPLVETYELLSNF 185
Cdd:PRK14367 161 IGGIFIQSIEGSFSGIMGLPVYETVSMLQDL 191
PRK14362 PRK14362
Maf-like protein; Provisional
 4-182 1.49e-49

Maf-like protein; Provisional


Pssm-ID: 172838  Cd Length: 207  Bit Score: 159.64  E-value: 1.49e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374    4 LYLASGSPRRQELLAQLGVTFERIVTGIEEQRQ-PQESAQQYVVRLAREKARAgVAQTAKDLPVLGADTIVILNGEVLEK 82
Cdd:PRK14362  14 VVLASGSPRRREFLEQMGLPFEVILPGAAEPSPiEGEQPEAYARRAAEAKARA-VAADHAGRLVIAADTVVALDGMILGK 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374   83 PRDAEHAAQMLRKLSGQTHQVMTA--VALADSRHILdCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCFV 160
Cdd:PRK14362  93 PADRADALSMLRRLAGRTHEVVSAccVVLPDGGREV-FHAITRVTMWDWPEAALAAYVATGEPSDKAGAYGIQGIGAFLV 171

                        170       180
                 ....*....|....*....|..
gi 15833374  161 RKINGSYQAVVGLPLVETYELL 182
Cdd:PRK14362 172 RSIEGSWSNVVGLPVAELTALL 193
PRK14361 PRK14361
Maf-like protein; Provisional
 6-182 1.56e-48

Maf-like protein; Provisional


Pssm-ID: 172837  Cd Length: 187  Bit Score: 156.63  E-value: 1.56e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374    6 LASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQqYVVRLAREKARAgVAQTAKDLPVLGADTIVILNGEVLEKPRD 85
Cdd:PRK14361   3 LASGSPRRRELLENLGVPFQVVVSGEAEDSTETDPAR-LAAELALLKARA-VARLHPDAVVIAADTVVALGGVLLAKPAD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374   86 AEHAAQMLRKLSGQTHQVMTAVALADSRHILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCFVRKING 165
Cdd:PRK14361  81 EAENEAFLRVLSGRTHQVYTGVAVLSRGTEQVGVERTDVTFRALTAAEISFYARSGEGLDKAGGYGIQGVGMALVSRVEG 160

                        170
                 ....*....|....*..
gi 15833374  166 SYQAVVGLPLVETYELL 182
Cdd:PRK14361 161 DYSNVVGFPLSLVIRLL 177
PRK14365 PRK14365
Maf-like protein; Provisional
 1-184 1.85e-47

Maf-like protein; Provisional


Pssm-ID: 237690  Cd Length: 197  Bit Score: 153.82  E-value: 1.85e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374    1 MTSLYLASGSPRRQELLAQL-GVTFERIVTGIEEQRQPQESAQQYVVRLAREKARaGVAQTAKDLPVLGADTIVILNGEV 79
Cdd:PRK14365   1 MRRIILASASPRRKELLKQLiGDNFLVYPSSYEEPPQPGLDPEELLLKHSLEKAR-DVAKHFDSGIIISADTSVFCNGEV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374   80 LEKPRDAEHAAQMLRKLSGQTHQVMTAVALADS---RHILDcLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLG 156
Cdd:PRK14365  80 LGKPASPENAEEMLEKLSGRKFLVITGLTVLDLdsgKEISE-IESTDVWMTELSREQILAYVRTGEPLDKAGAFAIQGKG 158

                        170       180
                 ....*....|....*....|....*...
gi 15833374  157 GCFVRKINGSYQAVVGLPLVETYELLSN 184
Cdd:PRK14365 159 AVLVEKIEGDFFNVVGLPLFRLGKILEK 186
PRK01441 PRK01441
Maf-like protein; Reviewed
 4-183 2.14e-46

Maf-like protein; Reviewed


Pssm-ID: 167232  Cd Length: 207  Bit Score: 151.41  E-value: 2.14e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374    4 LYLASGSPRRQELLAQLGVTFERIV-TGIEEQRQPQESAQQYVVRLAREKARAGVAQTAKDLP-----VLGADTIVILNG 77
Cdd:PRK01441   7 LVLASGSPRRVELLNQAGIEPDRLMpADIDETPKRAEHPRSLARRLSREKAEAALEALQGDDDwrgayILAADTVVAVGR 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374   78 EVLEKPRDAEHAAQMLRKLSGQTHQVMTAVAL-ADSRHILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLG 156
Cdd:PRK01441  87 RILPKAELVDEASQCLRLLSGRNHRVYTGVCLvTPDGKLRQKLVETRVRFKRLSREDIEAYLASGEWRGKAGGYAIQGIA 166

                        170       180
                 ....*....|....*....|....*..
gi 15833374  157 GCFVRKINGSYQAVVGLPLVETYELLS 183
Cdd:PRK01441 167 GSFVVKLVGSYTNVVGLPLYETVSLLA 193
PRK14366 PRK14366
Maf-like protein; Provisional
 1-185 4.88e-44

Maf-like protein; Provisional


Pssm-ID: 237691  Cd Length: 195  Bit Score: 145.33  E-value: 4.88e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374    1 MTSLYLASGSPRRQELLAQLGVTFERIVT-GIEEQRQPQESAQQYVVRLAREKARAgVAQTAKDLPVLGADTIVILNGEV 79
Cdd:PRK14366   4 FDNLILASSSKQRLALLEQIGVVPGEIVSpDIDESPLKKELPKDYSIRMAKEKAEK-VQSLRPDKFVLGADTVVCCGRRI 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374   80 LEKPRDAEHAAQMLRKLSGQTHQVMTAVALADSRHILDCL-VVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGC 158
Cdd:PRK14366  83 LLKAETEEQAEEYLELLSGRRHRVYTSVCLYTPGGKLHIRsVVTVVKFKRLSKQEIKYYIASGEWKGKAGGCNIQGLAGK 162

                        170       180
                 ....*....|....*....|....*..
gi 15833374  159 FVRKINGSYQAVVGLPLVETYELLSNF 185
Cdd:PRK14366 163 FVLSINGSYSSIIGLPLHETYCLLSGY 189
PRK14363 PRK14363
Maf-like protein; Provisional
 4-182 9.49e-43

Maf-like protein; Provisional


Pssm-ID: 184647  Cd Length: 204  Bit Score: 142.34  E-value: 9.49e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374    4 LYLASGSPRRQELLAQLGVTFERIVTGIEEQRQpqESAQQYVVRLAREKArAGVAQTAK--DLPVLGADTIVILNGEVLE 81
Cdd:PRK14363   3 IILASSSPRRRQLMELLGIEFEVEKPDVEEEFL--ESPEETVRELSLRKA-EWVFKKRKeeEILVIGSDTVVVLDGNILG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374   82 KPRDAEHAAQMLRKLSGQTHQVMTAVALADSRHILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCFVR 161
Cdd:PRK14363  80 KPESLEEAKGMLKKLSGRWHVVYTGVAFVSSETKDVIVSSTKVRFRELPESVIDYYVEKYRPLDKAGAYGIQDFAAVFVE 159

                        170       180
                 ....*....|....*....|.
gi 15833374  162 KINGSYQAVVGLPLVETYELL 182
Cdd:PRK14363 160 KIEGDFFTVVGFPLGMVWQYL 180
Maf_Ham1 cd00985
Maf_Ham1. Maf, a nucleotide binding protein, has been implicated in inhibition of septum ...
 4-126 7.42e-40

Maf_Ham1. Maf, a nucleotide binding protein, has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea. A Ham1-related protein from Methanococcus jannaschii is a novel NTPase that has been shown to hydrolyze nonstandard nucleotides, such as hypoxanthine/xanthine NTP, but not standard nucleotides.


Pssm-ID: 238485  Cd Length: 131  Bit Score: 132.24  E-value: 7.42e-40
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374   4 LYLASGSPRRQELLAQLG-VTFERIVTGIEEqRQPQESAQQYVVRLAREKARAgVAQTAKDLPVLGADTIVILNGEVLEK 82
Cdd:cd00985   1 LILASGSPRRLEELKQIGgIEFEVLPSDIDE-TGLKGEPEDTVEELALLKARA-VAERLPDAPVIADDTGLVVDGRPGGK 78

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*
gi 15833374  83 PRDAEHAAQMLRKLSGQTHQVMTAVALAD-SRHILDCLVVTDVTF 126
Cdd:cd00985  79 PARFAEALEMLRGLSGRTAEFVTAVALVDpDGKIITFEGETEGKI 123
PRK02141 PRK02141
Maf-like protein; Reviewed
 4-186 3.79e-31

Maf-like protein; Reviewed


Pssm-ID: 235009  Cd Length: 207  Bit Score: 112.54  E-value: 3.79e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374    4 LYLASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQYVVRLAREKARAgVAQTAKDLP---VLGADTIVILNGEVL 80
Cdd:PRK02141  11 LILASSSRYRRELLERLRLPFDVVSPDIDETPLAGETPAATALRLAAAKARA-VAATIDAPPgalVIGSDQVATFDGLQI 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374   81 EKPRDAEHAAQMLRKLSGQTHQVMTAVALADSR----HILDclVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLG 156
Cdd:PRK02141  90 GKPGTHERALAQLQAMRGRTVEFHSALCLYDSRtgetQSED--VVTRVRFRTLTDAELDAYLRAETPYDVAGSAKSEGLG 167

                        170       180       190
                 ....*....|....*....|....*....|.
gi 15833374  157 GCFVRKINGS-YQAVVGLPLVETYELLSNFN 186
Cdd:PRK02141 168 IALLDAIDSDdPTALVGLPLIALTRMLRAAG 198
PRK02478 PRK02478
Maf-like protein; Reviewed
 2-175 9.25e-25

Maf-like protein; Reviewed


Pssm-ID: 167380  Cd Length: 199  Bit Score: 95.57  E-value: 9.25e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374    2 TSLYLASGSPRRQELLAQLGVTFERIVTGIEEQ--RQPQESA----QQYVVRLAREKARAgVAQTAKDLPVLGADTIVIL 75
Cdd:PRK02478   3 VKLILASKSPFRRALLENAGLEFSAAAADIDERavEAPLEESgatpEDVALVLAEAKAID-VSERFPGALVIGCDQTMSL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374   76 NGEVLEKPRDAEHAAQMLRKLSGQTHQVMTAVALA-DSRHILDCLVVTDVTFRTLTDEDIAGYVAS-GE-PLDKAGAYGI 152
Cdd:PRK02478  82 GDEVFHKPKDMEEARRHLQKLSGKTHQLNSAVVLVrDGKVLWRHVSIAHMTMRDLDAGFIGRHLARvGEkALSSVGAYQL 161

                        170       180
                 ....*....|....*....|...
gi 15833374  153 QGLGGCFVRKINGSYQAVVGLPL 175
Cdd:PRK02478 162 EGEGIQLFEKIEGDYFTILGLPL 184
PRK04056 PRK04056
septum formation inhibitor Maf;
4-173 1.24e-23

septum formation inhibitor Maf;


Pssm-ID: 179732  Cd Length: 180  Bit Score: 92.33  E-value: 1.24e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374    4 LYLASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQYVVRLAREKARAGVAQTAKDLPVLGADTIVILNGEVLEKP 83
Cdd:PRK04056   2 IILASSSSTRANLLKEAGIEFEQKSLDFDEESIKKTSPKEFVYLAVKGKLEQFLKKYGNECNLLVADSVVSCGNKILRKA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833374   84 RDAEHAAQMLRKLSGQTHQVMTAVALADSRHILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCFVRKI 163
Cdd:PRK04056  82 KDKEEAREMLKLQSGNEISVLTCMILKSPEKEWLDLSVTTYRFKKFDEDDLEKYLESGLWQGKAGACMVEGFHKKYIKSV 161

                        170
                 ....*....|
gi 15833374  164 NGSYQAVVGL 173
Cdd:PRK04056 162 SGNESTAMGL 171
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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