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Conserved domains on  [gi|15832340|ref|NP_311113|]
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cytochrome c-type biogenesis protein CcmE [Escherichia coli O157:H7 str. Sakai]

Protein Classification

cytochrome c maturation protein CcmE( domain architecture ID 10014124)

cytochrome c maturation protein CcmE acts as a heme chaperone required for the biogenesis of c-type cytochromes

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK13150 PRK13150
cytochrome c maturation protein CcmE;
1-159 1.34e-111

cytochrome c maturation protein CcmE;


:

Pssm-ID: 139376  Cd Length: 159  Bit Score: 313.46  E-value: 1.34e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832340    1 MNIRRKNRLWIACAVLAGLALTIGLVLYALRSNIDLFYTPGEILYGKRETQQMPEVGQRLRVGGMVMPGSVQRDPNSLKV 80
Cdd:PRK13150   1 MNLRRKNRLWVVCAVLAGLGLTTALVLYALRANIDLFYTPGEILYGKRETQQLPAVGQRLRVGGMVMPGSVRRDPDSLKV 80
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15832340   81 TFTIYDAEGSVDVSYEGILPDLFREGQGVVVQGELEKGNHILAKEVLAKHDENYTPPEVEKAMEANHRRPASVYKDPAS 159
Cdd:PRK13150  81 NFSLYDAEGSVTVSYEGILPDLFREGQGVVVQGTLEKGNHVLAHEVLAKHDENYTPPEVEKAMQENHRRPQRADKDTSS 159
 
Name Accession Description Interval E-value
PRK13150 PRK13150
cytochrome c maturation protein CcmE;
1-159 1.34e-111

cytochrome c maturation protein CcmE;


Pssm-ID: 139376  Cd Length: 159  Bit Score: 313.46  E-value: 1.34e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832340    1 MNIRRKNRLWIACAVLAGLALTIGLVLYALRSNIDLFYTPGEILYGKRETQQMPEVGQRLRVGGMVMPGSVQRDPNSLKV 80
Cdd:PRK13150   1 MNLRRKNRLWVVCAVLAGLGLTTALVLYALRANIDLFYTPGEILYGKRETQQLPAVGQRLRVGGMVMPGSVRRDPDSLKV 80
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15832340   81 TFTIYDAEGSVDVSYEGILPDLFREGQGVVVQGELEKGNHILAKEVLAKHDENYTPPEVEKAMEANHRRPASVYKDPAS 159
Cdd:PRK13150  81 NFSLYDAEGSVTVSYEGILPDLFREGQGVVVQGTLEKGNHVLAHEVLAKHDENYTPPEVEKAMQENHRRPQRADKDTSS 159
CcmE COG2332
Cytochrome c biogenesis protein CcmE [Energy production and conversion, Posttranslational ...
1-151 8.16e-79

Cytochrome c biogenesis protein CcmE [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441903  Cd Length: 148  Bit Score: 230.10  E-value: 8.16e-79
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832340   1 MNIRRKNRLWIACAVLAGLALTIGLVLYALRSNIDLFYTPGEILYGKretqqmPEVGQRLRVGGMVMPGSVQRDPNSLKV 80
Cdd:COG2332   1 MTPRRKKRLKLVVAGLVALGAAVALVLYALRDNIVYFYTPSEVAAGK------APPGRRIRVGGLVVPGSVQRDPDGLTV 74
                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15832340  81 TFTIYDAEGSVDVSYEGILPDLFREGQGVVVQGELEKGNHILAKEVLAKHDENYTPPEVEKAMEANHRRPA 151
Cdd:COG2332  75 RFVVTDGGATVPVRYTGILPDLFREGQGVVAEGRLDPDGVFEADEVLAKHDENYMPPEVADALKKAGVWQG 145
CcmE pfam03100
CcmE; CcmE is the product of one of a cluster of Ccm genes that are necessary for cytochrome c ...
4-137 1.10e-65

CcmE; CcmE is the product of one of a cluster of Ccm genes that are necessary for cytochrome c biosynthesis in eubacteria. Expression of these proteins is induced when the organizms are grown under anaerobic conditions with nitrate or nitrite as the final electron acceptor.


Pssm-ID: 460805  Cd Length: 129  Bit Score: 196.17  E-value: 1.10e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832340     4 RRKNRLWIACAVLAGLALTIGLVLYALRSNIDLFYTPGEILYGKretqqMPEVGQRLRVGGMVMPGSVQRDPNSLKVTFT 83
Cdd:pfam03100   1 RRKRRLKLLLAGLVALGAAVYLVLSALRDNIVYFLTPSEVLAGP-----APLAGRRIRLGGLVVPGSVKRDPDGLTVRFV 75
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 15832340    84 IYDAEGSVDVSYEGILPDLFREGQGVVVQGELEKGNHILAKEVLAKHDENYTPP 137
Cdd:pfam03100  76 VTDGGATLPVVYTGILPDLFREGQGVVVEGRLGPDGVFVADEVLAKHDEKYMPP 129
 
Name Accession Description Interval E-value
PRK13150 PRK13150
cytochrome c maturation protein CcmE;
1-159 1.34e-111

cytochrome c maturation protein CcmE;


Pssm-ID: 139376  Cd Length: 159  Bit Score: 313.46  E-value: 1.34e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832340    1 MNIRRKNRLWIACAVLAGLALTIGLVLYALRSNIDLFYTPGEILYGKRETQQMPEVGQRLRVGGMVMPGSVQRDPNSLKV 80
Cdd:PRK13150   1 MNLRRKNRLWVVCAVLAGLGLTTALVLYALRANIDLFYTPGEILYGKRETQQLPAVGQRLRVGGMVMPGSVRRDPDSLKV 80
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15832340   81 TFTIYDAEGSVDVSYEGILPDLFREGQGVVVQGELEKGNHILAKEVLAKHDENYTPPEVEKAMEANHRRPASVYKDPAS 159
Cdd:PRK13150  81 NFSLYDAEGSVTVSYEGILPDLFREGQGVVVQGTLEKGNHVLAHEVLAKHDENYTPPEVEKAMQENHRRPQRADKDTSS 159
PRK13165 PRK13165
cytochrome c maturation protein CcmE;
1-159 1.51e-111

cytochrome c maturation protein CcmE;


Pssm-ID: 183874  Cd Length: 160  Bit Score: 313.47  E-value: 1.51e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832340    1 MNIRRKNRLWIACAVLAGLALTIGLVLYALRSNIDLFYTPGEILYGKRETQQMPEVGQRLRVGGMVMPGSVQRDPNSLKV 80
Cdd:PRK13165   1 MNPRRKKRLWLACAVLAGLALTIGLVLYALRSNIDLFYTPGEILYGKRETQQKPEVGQRLRVGGMVMPGSVQRDPNSLKV 80
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15832340   81 TFTIYDAEGSVDVSYEGILPDLFREGQGVVVQGELEKGNHILAKEVLAKHDENYTPPEVEKAMEANHRRPASVYKDPAS 159
Cdd:PRK13165  81 SFTLYDAGGSVTVTYEGILPDLFREGQGIVAQGVLEEGNHIEAKEVLAKHDENYTPPEVEEAMKKNHRRPAYSYKDKAS 159
CcmE COG2332
Cytochrome c biogenesis protein CcmE [Energy production and conversion, Posttranslational ...
1-151 8.16e-79

Cytochrome c biogenesis protein CcmE [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441903  Cd Length: 148  Bit Score: 230.10  E-value: 8.16e-79
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832340   1 MNIRRKNRLWIACAVLAGLALTIGLVLYALRSNIDLFYTPGEILYGKretqqmPEVGQRLRVGGMVMPGSVQRDPNSLKV 80
Cdd:COG2332   1 MTPRRKKRLKLVVAGLVALGAAVALVLYALRDNIVYFYTPSEVAAGK------APPGRRIRVGGLVVPGSVQRDPDGLTV 74
                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15832340  81 TFTIYDAEGSVDVSYEGILPDLFREGQGVVVQGELEKGNHILAKEVLAKHDENYTPPEVEKAMEANHRRPA 151
Cdd:COG2332  75 RFVVTDGGATVPVRYTGILPDLFREGQGVVAEGRLDPDGVFEADEVLAKHDENYMPPEVADALKKAGVWQG 145
CcmE pfam03100
CcmE; CcmE is the product of one of a cluster of Ccm genes that are necessary for cytochrome c ...
4-137 1.10e-65

CcmE; CcmE is the product of one of a cluster of Ccm genes that are necessary for cytochrome c biosynthesis in eubacteria. Expression of these proteins is induced when the organizms are grown under anaerobic conditions with nitrate or nitrite as the final electron acceptor.


Pssm-ID: 460805  Cd Length: 129  Bit Score: 196.17  E-value: 1.10e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832340     4 RRKNRLWIACAVLAGLALTIGLVLYALRSNIDLFYTPGEILYGKretqqMPEVGQRLRVGGMVMPGSVQRDPNSLKVTFT 83
Cdd:pfam03100   1 RRKRRLKLLLAGLVALGAAVYLVLSALRDNIVYFLTPSEVLAGP-----APLAGRRIRLGGLVVPGSVKRDPDGLTVRFV 75
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 15832340    84 IYDAEGSVDVSYEGILPDLFREGQGVVVQGELEKGNHILAKEVLAKHDENYTPP 137
Cdd:pfam03100  76 VTDGGATLPVVYTGILPDLFREGQGVVVEGRLGPDGVFVADEVLAKHDEKYMPP 129
PRK13254 PRK13254
cytochrome c maturation protein CcmE;
1-148 1.81e-64

cytochrome c maturation protein CcmE;


Pssm-ID: 237317  Cd Length: 148  Bit Score: 193.93  E-value: 1.81e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832340    1 MNIRRKNRLWIACAVLAGLALTIGLVLYALRSNIDLFYTPGEILygkretQQMPEVGQRLRVGGMVMPGSVQRDpNSLKV 80
Cdd:PRK13254   1 MMKRKRRRLLIILGALAALGLAVALVLYALRQNIVFFYTPSEVA------EGEAPAGRRFRLGGLVEKGSVQRG-DGLTV 73
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15832340   81 TFTIYDAEGSVDVSYEGILPDLFREGQGVVVQGELEKGNHILAKEVLAKHDENYTPPEVEKAMEANHR 148
Cdd:PRK13254  74 RFVVTDGNATVPVVYTGILPDLFREGQGVVAEGRLQDGGVFVADEVLAKHDENYMPKEVADALKKAGV 141
PRK13159 PRK13159
cytochrome c-type biogenesis protein CcmE; Reviewed
1-147 2.61e-43

cytochrome c-type biogenesis protein CcmE; Reviewed


Pssm-ID: 183873  Cd Length: 155  Bit Score: 140.52  E-value: 2.61e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832340    1 MNIRRKNRLWIACAVLAGLALTIGLVLYALRSNIDLFYTPGEILYGKRETQQmpevgqRLRVGGMVMPGSVQRDPNSLKV 80
Cdd:PRK13159   1 MNATRKQRLWLVIGVLTAAALAVTLIVLALQRNMSYLFTPSQVRAGAAAGYQ------QFRLGGMVKAGSIQRAADSLKV 74
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15832340   81 TFTIYDAEGSVDVSYEGILPDLFREGQGVVVQGELEkGNHILAKEVLAKHDENYTPPEVEKAMEANH 147
Cdd:PRK13159  75 SFTVIDKNAATQVEYTGILPDLFRDNQSVIANGRMQ-GGRFVANEVLAKHDETYMPKELKDAMAEGH 140
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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