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Conserved domains on  [gi|15600292|ref|NP_253786|]
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transporter [Pseudomonas aeruginosa PAO1]

Protein Classification

purine-cytosine permease family protein( domain architecture ID 10003700)

purine-cytosine permease family protein is part of a family of transporters of purine- and pyrimidine-derivatives such as adenine, guanine, cytosine, and vitamin B6

Gene Ontology:  GO:0055085|GO:0016020
TCDB:  2.A.39

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
CodB COG1457
Purine-cytosine permease or related protein [Nucleotide transport and metabolism];
2-462 1.07e-96

Purine-cytosine permease or related protein [Nucleotide transport and metabolism];


:

Pssm-ID: 441066 [Multi-domain]  Cd Length: 448  Bit Score: 298.70  E-value: 1.07e-96
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292   2 TQGSDSKPLIERRSIDYIPANERHGRLYSQFTLWLGANLQITAIVTGALaVVLGGDVFWSLVGLLLGQLLGGAVMALHAA 81
Cdd:COG1457   5 SRRSNRAETVEDYGLEPVPESERHGSPRSLFWVWFGANVALATFVIGAL-LGLGLGFWQALLAILLGNLIGFLLGALIAY 83
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292  82 QGPRLGLPQMISSRVQFGVYGACIPIALVCLMYLGFTATGTVLSGQAIGQLTGLSD---SAGIFIFAAFIVLVTVLGYRV 158
Cdd:COG1457  84 IGARTGLPTMLLSRAAFGYRGSTLPSLLNALTTIGWFAVEAAIAAQALAALLGGLGiplVLAYLIVGLLVILLAIFGYRA 163
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 159 IHIIGRIASVLGIIAFAYLFSRLMLLSDIGDLLAI-RHFSWASFLLAVSLAASWQIAFGPYVADYSRYLPASTSSWKTFL 237
Cdd:COG1457 164 ISRLQRWAVPLLLVLFVLLVVLALSHPGLSALLAYpPGSSPLSFGAAVSVVAGLFISWAPYAADYSRYLPRKTSGRAVFW 243
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 238 AVGLGSVLGAQASMVLGVFSAALANGqfAGREVAYIVGLGSSGtVAALLYFSIAFGKVTISTLNSYGSFMCIATIISsvr 317
Cdd:COG1457 244 ATFLGFVLGGVLLMLLGALLAAAAPG--AADPVGALGALLPTG-LGVPALLVVILSQWTINVLNLYSASLALSNLFP--- 317
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 318 gqleitRVQRLFFVLAIVGASTLIALLGqhsFLAAFKSFILFLLTFFTPWSAVNLVDYYFITRERYDVPALADPDGRYGR 397
Cdd:COG1457 318 ------RLGRVVATLVVGVIGTLLALLG---FLDAFENFLLLLGVVLPPWGGIMLADYFLVRRGRYDPDALFDRRGRYGG 388
                       410       420       430       440       450       460
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15600292 398 WNLPGIAVYTLGVLVQMPFLATTLYTGPMVehlggVDISWIIGLLVPAVLYYLVARRKATRQAPA 462
Cdd:COG1457 389 VNWVGLIAWLLGSVVGILFVNTPGLFGPAL-----ADLSWLVALVVAAVLYLLLARYYLARPEAA 448
 
Name Accession Description Interval E-value
CodB COG1457
Purine-cytosine permease or related protein [Nucleotide transport and metabolism];
2-462 1.07e-96

Purine-cytosine permease or related protein [Nucleotide transport and metabolism];


Pssm-ID: 441066 [Multi-domain]  Cd Length: 448  Bit Score: 298.70  E-value: 1.07e-96
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292   2 TQGSDSKPLIERRSIDYIPANERHGRLYSQFTLWLGANLQITAIVTGALaVVLGGDVFWSLVGLLLGQLLGGAVMALHAA 81
Cdd:COG1457   5 SRRSNRAETVEDYGLEPVPESERHGSPRSLFWVWFGANVALATFVIGAL-LGLGLGFWQALLAILLGNLIGFLLGALIAY 83
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292  82 QGPRLGLPQMISSRVQFGVYGACIPIALVCLMYLGFTATGTVLSGQAIGQLTGLSD---SAGIFIFAAFIVLVTVLGYRV 158
Cdd:COG1457  84 IGARTGLPTMLLSRAAFGYRGSTLPSLLNALTTIGWFAVEAAIAAQALAALLGGLGiplVLAYLIVGLLVILLAIFGYRA 163
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 159 IHIIGRIASVLGIIAFAYLFSRLMLLSDIGDLLAI-RHFSWASFLLAVSLAASWQIAFGPYVADYSRYLPASTSSWKTFL 237
Cdd:COG1457 164 ISRLQRWAVPLLLVLFVLLVVLALSHPGLSALLAYpPGSSPLSFGAAVSVVAGLFISWAPYAADYSRYLPRKTSGRAVFW 243
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 238 AVGLGSVLGAQASMVLGVFSAALANGqfAGREVAYIVGLGSSGtVAALLYFSIAFGKVTISTLNSYGSFMCIATIISsvr 317
Cdd:COG1457 244 ATFLGFVLGGVLLMLLGALLAAAAPG--AADPVGALGALLPTG-LGVPALLVVILSQWTINVLNLYSASLALSNLFP--- 317
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 318 gqleitRVQRLFFVLAIVGASTLIALLGqhsFLAAFKSFILFLLTFFTPWSAVNLVDYYFITRERYDVPALADPDGRYGR 397
Cdd:COG1457 318 ------RLGRVVATLVVGVIGTLLALLG---FLDAFENFLLLLGVVLPPWGGIMLADYFLVRRGRYDPDALFDRRGRYGG 388
                       410       420       430       440       450       460
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15600292 398 WNLPGIAVYTLGVLVQMPFLATTLYTGPMVehlggVDISWIIGLLVPAVLYYLVARRKATRQAPA 462
Cdd:COG1457 389 VNWVGLIAWLLGSVVGILFVNTPGLFGPAL-----ADLSWLVALVVAAVLYLLLARYYLARPEAA 448
SLC-NCS1sbd_CobB-like cd11484
nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; This NCS1 ...
20-454 1.41e-91

nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; This NCS1 subfamily includes Escherichia coli CodB (cytosine permease), and the Saccharomyces cerevisiae transporters: Fcy21p (Purine-cytosine permease), and vitamin B6 transporter Tpn1. NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. NCS1s belong to a superfamily which also contains the solute carrier 5 family sodium/glucose transporters (SLC5s), and solute carrier 6 family neurotransmitter transporters (SLC6s).


Pssm-ID: 271377 [Multi-domain]  Cd Length: 406  Bit Score: 284.12  E-value: 1.41e-91
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292  20 PANERHGRLYSQFTLWLGANLQITAIVTGALAVVLGGDvFWSLVGLLLGQLLGGAVMALHAAQGPRLGLPQMISSRVQFG 99
Cdd:cd11484   1 VPEERRKSFLSMFSVWLGANFFLASMVTGALLGVGLSL-SQAILAVLLGNLIGGAYMALLGYIGARTGLPQMLLSRASFG 79
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 100 VYGACIPIALVCLMYLGFTATGTVLSGQAIGQLTGLSDS--AGIFIFAAFIVLVTVLGYRVIHIIGRIASVLGIIAFAYL 177
Cdd:cd11484  80 EKGSYLPSLLLGITQIGWFGVGTAMFAIALSKLLGINGSlwLLILIAGVLMTLTAIFGYKALHKLEKIAVPLIIALFVYS 159
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 178 FSRLMLLSDIGDLLAIRHFSWASFLLAVSLAASWQIAFGPYVADYSRYLpasTSSWKTFLAVGLGSVLGAQASMVLGVFS 257
Cdd:cd11484 160 VVLALRDYGVGGLAALTATGPLSFLVAVSLVAGSFISGATYTADYSRYA---KSSKKAFWATFLGFFVGNSLMMILGALL 236
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 258 AALANGqfaGREVAYIVGLGssgtVAALLYFSIAFGKVTISTLNSYGSFMCIATIISSVrgqleitRVQRLFFVLAIVGA 337
Cdd:cd11484 237 AAATGT---ADISEVMIAQG----LGIPAILVLVLNIWTTNDNNLYSSGLSLSNITKIF-------RRKVLTLVAGIVGT 302
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 338 StLIALLGQHSFLAafksFILFLLTFFTPWSAVNLVDYYFITRERYDVPALADPDgrYGRWNLPGIAVYTLGVLVQMPFL 417
Cdd:cd11484 303 L-LAALGIYNHFLN----FLLLLGYALPPWGGVMLADYFVVRRGRYDIDALADPQ--YGGVNWAALIAWAVGVAVGIPFP 375
                       410       420       430
                ....*....|....*....|....*....|....*..
gi 15600292 418 ATTlytgpmvehLGGVDISWIIGLLVPAVLYYLVARR 454
Cdd:cd11484 376 YGL---------LGGGGIAPINGLLVAAVVYYILRKI 403
Transp_cyt_pur pfam02133
Permease for cytosine/purines, uracil, thiamine, allantoin;
18-440 9.50e-34

Permease for cytosine/purines, uracil, thiamine, allantoin;


Pssm-ID: 251109  Cd Length: 439  Bit Score: 132.13  E-value: 9.50e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292    18 YIPANERHGRLYSQFTLWLGANLQITAIVTGALAVVLGGDVFWSLVGLLLGQLLGGAVMALHAAQGPRLGLPQMISSRVQ 97
Cdd:pfam02133   1 PVPEEERTWSTRNLFSFWLGANFNINTWVIGALGVALGLNWWQSVLAIIAGNLIGAIFVALLGRAGAKYGLPFPILSRAS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292    98 FGVYGACIPIALVCLMYLGFTATGTVLSGQA----IGQLTGLSDSAGIFIFAAFIVLVTVLGYRVIHIIGR--------- 164
Cdd:pfam02133  81 FGIRGSLLPSLLRAVIACGWFGIQAWIGSEAlllmLGKIFGHWLWIGAIPGTGLTELVTFFIFWLVHLYIVwlgvsairv 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292   165 ----IASVLGIIAFAYLFSRLMLLSDIGDLLAIRHFSWA-SFLLAVSLAASWQIAFGPYVADYSRYLPASTSSWKTFL-A 238
Cdd:pfam02133 161 ffviAAPLIPVAAFGFLIWAAVKAGGGPVFDQPVSPGKSeLFLSAVAGCAAGWATLIANAPDFTRYAPTARSSSKIQLvA 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292   239 VGLGSVLGAQASMVLGVFSAALANGQFAgrEVAYIVGLGSSGTVAALLYFSIAFGKVTISTLNSYGSFMCIATIISSVRg 318
Cdd:pfam02133 241 VPGGFTLFALIGILGAAAAYAAYGAPAW--DPLDILARFDPTAGVFLPAILVALAQLGTNISANLYSAGSDLAALLPKK- 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292   319 qleITRVQRLFFVLAIVGASTLIALLGQHSFLaaFKSFILFLLTFFTPWSAVNLVDYYFITRERYDVPAL--ADPDGRY- 395
Cdd:pfam02133 318 ---INRKRGSLIAAIIALVICPWKLLGNSAFM--FTTFLSLLSGFLSPVAGVIIADYFVVRRGYLHVAHLytRRRGSAYw 392
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*..
gi 15600292   396 --GRWNLPGIAVYTLGVLVQMPFLATTLYTGPMVEHLGGVDISWIIG 440
Cdd:pfam02133 393 yrGGVNWRAFAAYIVGIAAGLPGFSGSVGIKVPPGAMLGFDLSYLVG 439
codB PRK11017
cytosine permease; Provisional
83-411 3.84e-05

cytosine permease; Provisional


Pssm-ID: 236821  Cd Length: 404  Bit Score: 45.68  E-value: 3.84e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292   83 GPRLGLPQMISSRVQFGVYGACIPIALVCLMYLGFTATGTVLSGQAIGQLTGLSDSAGIFIFAAFIVLVTVLGYRVIHII 162
Cdd:PRK11017  66 GAKTGLSTHLLARFSFGEKGSWLPSLLLGFTQVGWFGVGVAMFAIPVVKATGLDINLLIVLSGLLMTVTAYFGISALTIL 145
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292  163 GRIASVLgiIAFAYLFSRLMLLSDIG---DLLAIRHFSWASFLLAVSLAASWQIAFGPYVADYSRY-LPASTSSWKTFLA 238
Cdd:PRK11017 146 SRIAVPA--IALLGGYSVWLAVNDVGgldGLKAIVPAEPLDFSAALTLVVGSFISGGTLTADFVRFgRSAKIAVLATMVA 223
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292  239 VGLGSVLgaqasMVLGVFSAALANGQFAGREVAYIVGLGSSGTVAALLyfsiafgkvTISTLNSygsfmciATIISSVRG 318
Cdd:PRK11017 224 FFLGNSL-----MFIFGAAGAAVYGQADISDVMIAQGLLIPAIVMLGL---------NIWTTND-------NALYASGLG 282
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292  319 QLEITRVQRLFFVLAIVGASTLIALLGQHSFLaafkSFILFLLTFFTPWSAVNLVDYYFITRERYdvPALAdpDGRYGRW 398
Cdd:PRK11017 283 FCNITRLSSRTLTVVNGIIGTVLALWLYNNFV----GWLTLLGSAIPPVGGVIIADYFMNRRGRY--PDFA--TARLPRV 354
                        330
                 ....*....|...
gi 15600292  399 NLPGIAVYTLGVL 411
Cdd:PRK11017 355 NWAAILAVALGAA 367
 
Name Accession Description Interval E-value
CodB COG1457
Purine-cytosine permease or related protein [Nucleotide transport and metabolism];
2-462 1.07e-96

Purine-cytosine permease or related protein [Nucleotide transport and metabolism];


Pssm-ID: 441066 [Multi-domain]  Cd Length: 448  Bit Score: 298.70  E-value: 1.07e-96
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292   2 TQGSDSKPLIERRSIDYIPANERHGRLYSQFTLWLGANLQITAIVTGALaVVLGGDVFWSLVGLLLGQLLGGAVMALHAA 81
Cdd:COG1457   5 SRRSNRAETVEDYGLEPVPESERHGSPRSLFWVWFGANVALATFVIGAL-LGLGLGFWQALLAILLGNLIGFLLGALIAY 83
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292  82 QGPRLGLPQMISSRVQFGVYGACIPIALVCLMYLGFTATGTVLSGQAIGQLTGLSD---SAGIFIFAAFIVLVTVLGYRV 158
Cdd:COG1457  84 IGARTGLPTMLLSRAAFGYRGSTLPSLLNALTTIGWFAVEAAIAAQALAALLGGLGiplVLAYLIVGLLVILLAIFGYRA 163
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 159 IHIIGRIASVLGIIAFAYLFSRLMLLSDIGDLLAI-RHFSWASFLLAVSLAASWQIAFGPYVADYSRYLPASTSSWKTFL 237
Cdd:COG1457 164 ISRLQRWAVPLLLVLFVLLVVLALSHPGLSALLAYpPGSSPLSFGAAVSVVAGLFISWAPYAADYSRYLPRKTSGRAVFW 243
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 238 AVGLGSVLGAQASMVLGVFSAALANGqfAGREVAYIVGLGSSGtVAALLYFSIAFGKVTISTLNSYGSFMCIATIISsvr 317
Cdd:COG1457 244 ATFLGFVLGGVLLMLLGALLAAAAPG--AADPVGALGALLPTG-LGVPALLVVILSQWTINVLNLYSASLALSNLFP--- 317
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 318 gqleitRVQRLFFVLAIVGASTLIALLGqhsFLAAFKSFILFLLTFFTPWSAVNLVDYYFITRERYDVPALADPDGRYGR 397
Cdd:COG1457 318 ------RLGRVVATLVVGVIGTLLALLG---FLDAFENFLLLLGVVLPPWGGIMLADYFLVRRGRYDPDALFDRRGRYGG 388
                       410       420       430       440       450       460
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15600292 398 WNLPGIAVYTLGVLVQMPFLATTLYTGPMVehlggVDISWIIGLLVPAVLYYLVARRKATRQAPA 462
Cdd:COG1457 389 VNWVGLIAWLLGSVVGILFVNTPGLFGPAL-----ADLSWLVALVVAAVLYLLLARYYLARPEAA 448
SLC-NCS1sbd_CobB-like cd11484
nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; This NCS1 ...
20-454 1.41e-91

nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; This NCS1 subfamily includes Escherichia coli CodB (cytosine permease), and the Saccharomyces cerevisiae transporters: Fcy21p (Purine-cytosine permease), and vitamin B6 transporter Tpn1. NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. NCS1s belong to a superfamily which also contains the solute carrier 5 family sodium/glucose transporters (SLC5s), and solute carrier 6 family neurotransmitter transporters (SLC6s).


Pssm-ID: 271377 [Multi-domain]  Cd Length: 406  Bit Score: 284.12  E-value: 1.41e-91
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292  20 PANERHGRLYSQFTLWLGANLQITAIVTGALAVVLGGDvFWSLVGLLLGQLLGGAVMALHAAQGPRLGLPQMISSRVQFG 99
Cdd:cd11484   1 VPEERRKSFLSMFSVWLGANFFLASMVTGALLGVGLSL-SQAILAVLLGNLIGGAYMALLGYIGARTGLPQMLLSRASFG 79
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 100 VYGACIPIALVCLMYLGFTATGTVLSGQAIGQLTGLSDS--AGIFIFAAFIVLVTVLGYRVIHIIGRIASVLGIIAFAYL 177
Cdd:cd11484  80 EKGSYLPSLLLGITQIGWFGVGTAMFAIALSKLLGINGSlwLLILIAGVLMTLTAIFGYKALHKLEKIAVPLIIALFVYS 159
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 178 FSRLMLLSDIGDLLAIRHFSWASFLLAVSLAASWQIAFGPYVADYSRYLpasTSSWKTFLAVGLGSVLGAQASMVLGVFS 257
Cdd:cd11484 160 VVLALRDYGVGGLAALTATGPLSFLVAVSLVAGSFISGATYTADYSRYA---KSSKKAFWATFLGFFVGNSLMMILGALL 236
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 258 AALANGqfaGREVAYIVGLGssgtVAALLYFSIAFGKVTISTLNSYGSFMCIATIISSVrgqleitRVQRLFFVLAIVGA 337
Cdd:cd11484 237 AAATGT---ADISEVMIAQG----LGIPAILVLVLNIWTTNDNNLYSSGLSLSNITKIF-------RRKVLTLVAGIVGT 302
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 338 StLIALLGQHSFLAafksFILFLLTFFTPWSAVNLVDYYFITRERYDVPALADPDgrYGRWNLPGIAVYTLGVLVQMPFL 417
Cdd:cd11484 303 L-LAALGIYNHFLN----FLLLLGYALPPWGGVMLADYFVVRRGRYDIDALADPQ--YGGVNWAALIAWAVGVAVGIPFP 375
                       410       420       430
                ....*....|....*....|....*....|....*..
gi 15600292 418 ATTlytgpmvehLGGVDISWIIGLLVPAVLYYLVARR 454
Cdd:cd11484 376 YGL---------LGGGGIAPINGLLVAAVVYYILRKI 403
Transp_cyt_pur pfam02133
Permease for cytosine/purines, uracil, thiamine, allantoin;
18-440 9.50e-34

Permease for cytosine/purines, uracil, thiamine, allantoin;


Pssm-ID: 251109  Cd Length: 439  Bit Score: 132.13  E-value: 9.50e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292    18 YIPANERHGRLYSQFTLWLGANLQITAIVTGALAVVLGGDVFWSLVGLLLGQLLGGAVMALHAAQGPRLGLPQMISSRVQ 97
Cdd:pfam02133   1 PVPEEERTWSTRNLFSFWLGANFNINTWVIGALGVALGLNWWQSVLAIIAGNLIGAIFVALLGRAGAKYGLPFPILSRAS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292    98 FGVYGACIPIALVCLMYLGFTATGTVLSGQA----IGQLTGLSDSAGIFIFAAFIVLVTVLGYRVIHIIGR--------- 164
Cdd:pfam02133  81 FGIRGSLLPSLLRAVIACGWFGIQAWIGSEAlllmLGKIFGHWLWIGAIPGTGLTELVTFFIFWLVHLYIVwlgvsairv 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292   165 ----IASVLGIIAFAYLFSRLMLLSDIGDLLAIRHFSWA-SFLLAVSLAASWQIAFGPYVADYSRYLPASTSSWKTFL-A 238
Cdd:pfam02133 161 ffviAAPLIPVAAFGFLIWAAVKAGGGPVFDQPVSPGKSeLFLSAVAGCAAGWATLIANAPDFTRYAPTARSSSKIQLvA 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292   239 VGLGSVLGAQASMVLGVFSAALANGQFAgrEVAYIVGLGSSGTVAALLYFSIAFGKVTISTLNSYGSFMCIATIISSVRg 318
Cdd:pfam02133 241 VPGGFTLFALIGILGAAAAYAAYGAPAW--DPLDILARFDPTAGVFLPAILVALAQLGTNISANLYSAGSDLAALLPKK- 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292   319 qleITRVQRLFFVLAIVGASTLIALLGQHSFLaaFKSFILFLLTFFTPWSAVNLVDYYFITRERYDVPAL--ADPDGRY- 395
Cdd:pfam02133 318 ---INRKRGSLIAAIIALVICPWKLLGNSAFM--FTTFLSLLSGFLSPVAGVIIADYFVVRRGYLHVAHLytRRRGSAYw 392
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*..
gi 15600292   396 --GRWNLPGIAVYTLGVLVQMPFLATTLYTGPMVEHLGGVDISWIIG 440
Cdd:pfam02133 393 yrGGVNWRAFAAYIVGIAAGLPGFSGSVGIKVPPGAMLGFDLSYLVG 439
SLC-NCS1sbd cd10323
nucleobase-cation-symport-1 (NCS1) transporters; solute-binding domain; NCS1s are essential ...
29-454 2.34e-20

nucleobase-cation-symport-1 (NCS1) transporters; solute-binding domain; NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. This family includes Microbacterium liquefaciens Mhp1, a transporter that mediates the uptake of indolyl methyl- and benzyl-hydantoins as part of a metabolic salvage pathway for their conversion to amino acids. It also includes various Saccharomyces cerevisiae transporters: Fcy21p (Purine-cytosine permease), vitamin B6 transporter Tpn1, nicotinamide riboside transporter 1 (Nrt1p, also called Thi71p), Dal4p (allantoin permease), Fui1p (uridine permease), and Fur4p (uracil permease). Mhp1 has 12 transmembrane (TM) helices (an inverted topology repeat: TMs1-5 and TMs6-10, and TMs11-12; TMs numbered to conform to the solute carrier 6 family Aquifex aeolicus LeuT). NCS1s belong to a superfamily which also contains the solute carrier 5 family sodium/glucose transporters (SLC5s), and SLC6 neurotransmitter transporters.


Pssm-ID: 271358  Cd Length: 414  Bit Score: 93.11  E-value: 2.34e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292  29 YSQFTLWLGANLQITAIVTGAlAVVLGGDVFWSLVGLLLGQLLGGAVMALHAAQGPRLGLPQMISSRVQFGVYGACIPIA 108
Cdd:cd10323   5 LSYLAMWLGDCVSIGTFTLGG-SLVGLGLLWQVILAILIGCLIIGIFLVLNGRIGYKYGIPFAVQLRASFGIKGSHIPSL 83
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 109 LVCLMYLGFTATGTVLSGQAIGQLTGLSDS-----AGIFIFAAFIVLVTVLGYRVIHIIGRIASVLGIIAFAYLFSRLML 183
Cdd:cd10323  84 LRGVPAIVWFGFQTWLGALALNEISGLLFGfdnivLCFIIFGLLQIVLSFFGIKAIKWLENIAAPAIIAALVYMFYLLVN 163
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 184 LSD--IGDLLAIRHFSW-ASFLLAVSLAASWQIAFGPYVADYSRYLPASTSSWKTFLAVGLGSVLGAQASMVLGVFSAAl 260
Cdd:cd10323 164 KAGdeIGENLWYKAGTWgLPFLVAIMAFVGNWAALALNAPDYSRELKPGKRNRNVGLAQFVALVPAFLFMGLIGAMSTA- 242
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 261 ANGQFAGREVAYIVGLGSSGTVAALLYfsIAFGKVTISTLNSYGSFMCIATIISSvrgqleitRVQRLFFVLAIVG-AST 339
Cdd:cd10323 243 ATGIWNPVDVIQGVVSNGFLLVLTLVF--IVLAQWSTNIAANIVPPAYVFMNLFP--------RKITYKTGVVIAGiLGL 312
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 340 LIALLGQHSFLAAFKSFILFLLTFFTPWSAVNLVDYYFITRERYDVPALADPDGRYGRW---NLPGIAVYTLGVLVQmpf 416
Cdd:cd10323 313 CICPWLLVNDLSALTTFLGIYSAFLGPIFGIMIADYYVLRRRRVNVDDLYDANGQYKYFkgvNWAAIIAMAVGAAAA--- 389
                       410       420       430
                ....*....|....*....|....*....|....*...
gi 15600292 417 lattlytgpmvehLGGVDISWIIGLLVPAVLYYLVARR 454
Cdd:cd10323 390 -------------LLLVDLSWFVGLIVAGLLYYPLMKR 414
SLC-NCS1sbd_NRT1-like cd11482
nucleobase-cation-symport-1 (NCS1) transporter NRT1-like; solute-binding domain; This fungal ...
14-450 9.90e-13

nucleobase-cation-symport-1 (NCS1) transporter NRT1-like; solute-binding domain; This fungal NCS1 subfamily includes various Saccharomyces cerevisiae transporters: nicotinamide riboside transporter 1 (Nrt1p, also called Thi71p), Dal4p (allantoin permease), Fui1p (uridine permease), Fur4p (uracil permease), and Thi7p (thiamine transporter). NCS1s are essential components of salvage pathways for nucleobases and related metabolites. NCS1s belong to a superfamily which also contains the solute carrier 5 family sodium/glucose transporters, and solute carrier 6 family neurotransmitter transporters.


Pssm-ID: 271375  Cd Length: 480  Bit Score: 69.85  E-value: 9.90e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292  14 RSIDYIPANERHGRLYSQFTLWLGANLQITAIVTGALAVVLGGDVFWSLVGLLLGQLLGGAVMALHAAQGPRLGLPQMIS 93
Cdd:cd11482   4 RDLDPVPPERRTWGWWSFFAYWISDSFNISTWQTGSSLLALGLSWWQAIGAVIIGNILIAIFVVLNGRPGAKYHIGFPVA 83
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292  94 SRVQFGVYGACIPIALVCLMYLGFTATGTVLSGQAIGQL------------TGLSDSAGI--------FIFAAFIVLVTV 153
Cdd:cd11482  84 SRASFGIYGSYFPVIIRVVLAIVWFGVQAWTGGQCVTVMlraifpsflnipNTLPASAGIttaqligfFLFWLIQLPFLF 163
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 154 LGYRVIHIIGRIASVLGIIAFAYLFSRLMLLSD-IGDL------LAIRHFSWAsFLLAVSLAASWQIAFGPYVADYSRYl 226
Cdd:cd11482 164 IPPEKLRHLFTVKAVIVPIAALGLLIWALAKAGgAGPLvsqpssLSGSALGWA-WLSGINSIIGGFSTLIVNQPDFTRY- 241
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 227 paSTSSWKTFLAVGLGSVLGAQASMVLGVFSAALANGQFagrEVAY-----IVGL-----GSSGTVAALLYFSIAFGKVT 296
Cdd:cd11482 242 --AKKPPDAVWGQLISIPLSGTLVPLLGILTTSASKVLY---GEAYwnpldLLDAwldhdYSAGARAAAFFAALGFALAQ 316
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 297 IST---LNSYGSFMCIATI----ISSVRGQLeitrvqrLFFVLAIV--------GASTLIALLGqhsflaafkSFILFLl 361
Cdd:cd11482 317 LGTnisANSISAGNDLTGLfpkyINIRRGAI-------ICAILGWAivpwkllnSASSFLTFLS---------SYSVFL- 379
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 362 tffTPWSAVNLVDYYFITRERYDVPAL--ADPDGRY---GRWNLPGIAVYTLGVLVQMPFLATTLytGPMVEHLGGV--- 433
Cdd:cd11482 380 ---APIAGIMIADYYIVRRGKLKLPDLytASPHGIYwytKGVNWRAFVAWLVGVAPNLPGLANSV--NPPVSVPGGAvrl 454
                       490
                ....*....|....*...
gi 15600292 434 -DISWIIGLLVPAVLYYL 450
Cdd:cd11482 455 yYLGYLLGFLISFVVYYV 472
SLC-NCS1sbd_YbbW-like cd11485
uncharacterized nucleobase-cation-symport-1 (NCS1) transporter subfamily, YbbW-like; ...
19-454 2.57e-12

uncharacterized nucleobase-cation-symport-1 (NCS1) transporter subfamily, YbbW-like; solute-binding domain; NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. This subfamily includes the putative allantoin transporter Escherichia coli YbbW (also known as GlxB2). NCS1s belong to a superfamily which also contains the solute carrier 5 family sodium/glucose transporters (SLC5s), and solute carrier 6 family neurotransmitter transporters (SLC6s).


Pssm-ID: 271378  Cd Length: 456  Bit Score: 68.75  E-value: 2.57e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292  19 IPANERHGRLYSQFTLWLGANLQITAIVTGALAVVLGGDVFWSLVGLLLGQLLGGAVMALHAAQGPRLGLPQMISSRVQF 98
Cdd:cd11485  12 VPPEQRTWTTWNYAALWIGMVHNIPTYMLASGLIALGMSWWQALLTVVLGNLIVLIPMVLNGHAGTKYGIPFPVLARASF 91
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292  99 GVYGACIPIALVCLMYLGFTATGTVLSGQAIGQLTGLS--------DSAGIFIFAAFIVLVTVL-GYRVIHIIGRIASVL 169
Cdd:cd11485  92 GVRGANIPALLRAIVACGWFGIQTWIGGQAIYAILGVLiwpgwlgiGFGQLFCFLLFPWALNVWiIYKGMESIRKLEAWA 171
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 170 G----IIAFAYLFSRLMLLSDIGDLLAIR-------HFSWASFLLAVSLAASWQIAFGPYVADYSRYLpastsswKTFLA 238
Cdd:cd11485 172 AplliLLSLALLIWAISKAGGFGPILSQPsafgpkgGNFWKVFFPALTAMIGFWATLALNIPDFTRFA-------KSQRA 244
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 239 VGLGSVLGAQASMVLGVFSAALAngqFAGREVAY-------IVGLGSSGTVAALLYFSIAFGKVTISTlNSYGSFMCIAT 311
Cdd:cd11485 245 QVLGQAIGLPITMALFAFVGVAV---TSATVVIFgeaiwdpVDLLSRFDNPAVVIIALLAIILATLST-NVAANLVSPAY 320
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 312 IISSVRGQLeITrVQRLFFVLAIVGASTLIALLGQHSFLAAFkSFILFLLTFFTPWSAVNLVDYYFITRERYDVPALADP 391
Cdd:cd11485 321 DFANLFPKK-IS-FRRGGLITAVLGLLIMPWKLLENADGYIF-TWLGGYGALLGPIAGIMIADYWLVRRTRLDLDDLYRR 397
                       410       420       430       440       450       460
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15600292 392 DGRY---GRWNLPGIAVYTLGVLVQMPflattlytGPMVEHLGGV-DISWIIGLLVPAVLYYLVARR 454
Cdd:cd11485 398 GGRYwysNGWNWRALIALAVGVLPALP--------GFLIPALKWLyDYAWFVGFAVAGLLYLLLMKR 456
FUI1 COG1953
Cytosine/uracil/thiamine/allantoin permease [Nucleotide transport and metabolism, Coenzyme ...
19-459 1.47e-11

Cytosine/uracil/thiamine/allantoin permease [Nucleotide transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 441556  Cd Length: 483  Bit Score: 66.37  E-value: 1.47e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292  19 IPANERHGRLYSQFTLWLGANLQITAIVTGALAVVLGGDVFWSLVGLLLGQLLGGAVMALHAAQGPRLGLPQMISSRVQF 98
Cdd:COG1953  28 TPAEKRTWGWYNIFALWMGMVHSVPGYTLAAGLFALGLSWWQALLALLLGNLIVLVPMNLNGHAGTKYGIPFPVLARASF 107
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292  99 GVYGACIPIALVCLMYLGFTATGTVLSGQAI--------GQLTGLSDSAGIFI--------FAAFIVLVTVLGYRVIHII 162
Cdd:COG1953 108 GVRGANIPALLRGLIAIGWFGIQTYLASQALdalllklfPGLASLGGAHSFLGlsalgwisFLLFWALQLLIFWRGMEAI 187
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 163 GRIAS-------VLGIIAFAYLFSRL----MLLSDIGDLLAIRHFsWASFLLAVSLAASWQIAFGPYVADYSRYLpasts 231
Cdd:COG1953 188 RKFEDwagplvyVVMLALAIWALSKAggfgPILSLPSKFLSGGAF-WAVFFPALTLMVAYWATLALNFPDFTRFA----- 261
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 232 swKTFLAVGLGSVLGAQASMVL-GVFSAALANGQFA--GREVAYIVGL-GSSGTVAALLYFSIAFGKVTISTlNSYGSFM 307
Cdd:COG1953 262 --KSQRAQVRGQFLGLPVNMLLfSFIGVVTTSATVVvfGEAIWDPVELvARIDSPFAVVLALLTFLIATVGI-NIVANFV 338
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 308 CIATIISSVRGqleitrvQRLFFVLAIVGASTLIALLGQHSFLAAFKSFILFLLT---FFTPWSAVNLVDYYFITRERYD 384
Cdd:COG1953 339 SPAYDFSNLFP-------KKISFRRGGLITAVIGLLITPWNLYNSPEGIFYFLGGlgaLLGPVFGILIADYYLVRRQRLD 411
                       410       420       430       440       450       460       470
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15600292 385 VPAL-ADPDGRY---GRWNLPGIAVYTLGVLVQMPFlattlYTGPMVEHLGgvDISWIIGLLVPAVLYYLVARRKATRQ 459
Cdd:COG1953 412 VDDLySEDDGRYwyrNGWNPRAVIALVVGAVISLAG-----ALVPALAPLY--DYSWFVGAALGGVLYLALMRRRPRAV 483
SLC-NCS1sbd_u1 cd11555
uncharacterized nucleobase-cation-symport-1 (NCS1) transporter subfamily; solute-binding ...
356-454 1.03e-06

uncharacterized nucleobase-cation-symport-1 (NCS1) transporter subfamily; solute-binding domain; NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. NCS1s belong to a superfamily which also contains the solute carrier 5 family sodium/glucose transporters (SLC5s), and solute carrier 6 family neurotransmitter transporters (SLC6s).


Pssm-ID: 271404  Cd Length: 461  Bit Score: 51.02  E-value: 1.03e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 356 FILFLLTFFTPWSAVNLVDYYFITRERYDVPAL--ADPDGRY---GRWNLPGIAVYTLGVLVqmpflATTLYTGPMVEHL 430
Cdd:cd11555 365 FLDGLGAFLGPLFGILIVDYYLVRKGRVDVPDLysDSPKGAYwyrNGWNPKAVAALVPAAAI-----SVLTVLVPALAAL 439
                        90       100
                ....*....|....*....|....
gi 15600292 431 GGvdISWIIGLLVPAVLYYLVARR 454
Cdd:cd11555 440 AG--FSWFIGAALGGVLYYLLARR 461
SLC-NCS1sbd_Mhp1-like cd11483
nucleobase-cation-symport-1 (NCS1) transporter Mhp1-like; solute-binding domain; This NCS1 ...
23-453 5.66e-06

nucleobase-cation-symport-1 (NCS1) transporter Mhp1-like; solute-binding domain; This NCS1 subfamily includes Microbacterium liquefaciens Mhp1, and various uncharacterized NCS1s. Mhp1 mediates the uptake of indolyl methyl- and benzyl-hydantoins as part of a metabolic salvage pathway for their conversion to amino acids. Mhp1 has 12 transmembrane (TM) helices (an inverted topology repeat: TMs1-5 and TMs6-10, and TMs11-12; TMs numbered to conform to the Solute carrier 6 (SLC6) family Aquifex aeolicus LeuT). NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their other known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. NCS1s belong to a superfamily which also contains the solute carrier 5 family sodium/glucose transporters (SLC5s), and SLC6 neurotransmitter transporters.


Pssm-ID: 271376  Cd Length: 451  Bit Score: 48.58  E-value: 5.66e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292  23 ERHGRLYSQFTLWLGANLQITAIVTGA-LAVVLGGDVFWSLVGLLLGQ-LLGGAVMALHAAQGPRLGLPQMISSRVQFGV 100
Cdd:cd11483  17 ERSMSLFDYAILWAGMTINVVAFSLGAqYYNGGDGLSPWTVIVVILIGyGIVTILTFLTGDIGTKYGVPFAVYARAPFGY 96
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 101 YGACIPI---ALVCLMYLGF-TATGTVLSGQAIGQLTGLSD-SAGIFIFAAFIVLVTVLGYRVIHIIGRIASVLGIIAFA 175
Cdd:cd11483  97 KGSLIAGllrAIPSLYWFGFqTWVGALALNEIMRILFGFSNlTLMIIIFAAIQVVNTMYGLKAMAKFDWIAIPVLAIMFV 176
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 176 YLFSRLMLLSDI--GDLLAIRHFSWASFLLAVSLAASWQIAFGPYVADYSRYLP----------------ASTSSWKTFL 237
Cdd:cd11483 177 AIVYLMLDKYNVslPEIMSTGGEGGYSFAFAIMGIAGGWITMALNGSDLVRQIKrdpnyenegffkrnkrAIIGQWLGLM 256
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 238 AVGLGSVLGAQASMVLgvfsaalaNGQFAGREVAYIVgLGSSGTVAALLYFSIAFGkvTISTlNSYGSFMCIATIISSVR 317
Cdd:cd11483 257 PVGIIFMLIGMASGIL--------TGEWDLNIVITEL-FGGSIPVLILFFIFILFA--QWST-NTAANLLPPAYVLLNIF 324
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292 318 GQLEitrvqrlFFVLAIVGASTLIALL----GQHSFLAAFKSFILFLLtffTPWSAVNLVDYYFITRERYDVPALADPDG 393
Cdd:cd11483 325 PKLK-------FKMSVIISGVIGLLMMpwkfQGVGFLVTFQNLISSML---GPIIGIMLADYFLIRKCKLNVHDLYRAGG 394
                       410       420       430       440       450       460
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15600292 394 RYGRW---NLPGIAVYTLGVLVqmpflatTLYTGpmvehlggvDISWIIGLLVPAVLYYLVAR 453
Cdd:cd11483 395 QYQYTngfNWSAVAALVVAFAV-------SLLTP---------DYAFFTGLIASLVLYIVLMK 441
codB PRK11017
cytosine permease; Provisional
83-411 3.84e-05

cytosine permease; Provisional


Pssm-ID: 236821  Cd Length: 404  Bit Score: 45.68  E-value: 3.84e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292   83 GPRLGLPQMISSRVQFGVYGACIPIALVCLMYLGFTATGTVLSGQAIGQLTGLSDSAGIFIFAAFIVLVTVLGYRVIHII 162
Cdd:PRK11017  66 GAKTGLSTHLLARFSFGEKGSWLPSLLLGFTQVGWFGVGVAMFAIPVVKATGLDINLLIVLSGLLMTVTAYFGISALTIL 145
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292  163 GRIASVLgiIAFAYLFSRLMLLSDIG---DLLAIRHFSWASFLLAVSLAASWQIAFGPYVADYSRY-LPASTSSWKTFLA 238
Cdd:PRK11017 146 SRIAVPA--IALLGGYSVWLAVNDVGgldGLKAIVPAEPLDFSAALTLVVGSFISGGTLTADFVRFgRSAKIAVLATMVA 223
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292  239 VGLGSVLgaqasMVLGVFSAALANGQFAGREVAYIVGLGSSGTVAALLyfsiafgkvTISTLNSygsfmciATIISSVRG 318
Cdd:PRK11017 224 FFLGNSL-----MFIFGAAGAAVYGQADISDVMIAQGLLIPAIVMLGL---------NIWTTND-------NALYASGLG 282
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600292  319 QLEITRVQRLFFVLAIVGASTLIALLGQHSFLaafkSFILFLLTFFTPWSAVNLVDYYFITRERYdvPALAdpDGRYGRW 398
Cdd:PRK11017 283 FCNITRLSSRTLTVVNGIIGTVLALWLYNNFV----GWLTLLGSAIPPVGGVIIADYFMNRRGRY--PDFA--TARLPRV 354
                        330
                 ....*....|...
gi 15600292  399 NLPGIAVYTLGVL 411
Cdd:PRK11017 355 NWAAILAVALGAA 367
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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