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Conserved domains on  [gi|15598616|ref|NP_252110|]
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transcriptional regulator [Pseudomonas aeruginosa PAO1]

Protein Classification

helix-turn-helix transcriptional regulator( domain architecture ID 11458467)

helix-turn-helix transcriptional regulator similar to HTH-type transcriptional regulator MalT regulates transcription of the maltose regulon and thus the uptake and catabolism of malto-oligosaccharides

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK04841 super family cl35271
HTH-type transcriptional regulator MalT;
12-823 4.46e-27

HTH-type transcriptional regulator MalT;


The actual alignment was detected with superfamily member PRK04841:

Pssm-ID: 235315 [Multi-domain]  Cd Length: 903  Bit Score: 118.12  E-value: 4.46e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616   12 PRLPPQHLPRPRLHQPLLRGEC-RLRLLCAPAGSGKTVLLGECARRAPpgvQVVWLALGGEALDPATFRRRLAGAL---- 86
Cdd:PRK04841  10 PVRLHNTVVRERLLAKLSGANNyRLVLVTSPAGYGKTTLISQWAAGKN---NLGWYSLDESDNQPERFASYLIAALqqat 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616   87 -GLPEDSDE--------------AQLCRRLRN-ASALWLLLDDYPRHPDPALDACLDRLLSAASPRVGWWLASRRRPQCN 150
Cdd:PRK04841  87 nGHCSKSEAlaqkrqyaslsslfAQLFIELADwHQPLYLVIDDYHLITNPEIHEAMRFFLRHQPENLTLVVLSRNLPPLG 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616  151 LARLLLEGELLEVDGGLLAFDADEVAELLRLHGRSA-DAATAGTLLERSGGWCAALRLRLLVGEETAGPLLQ-------- 221
Cdd:PRK04841 167 IANLRVRDQLLEIGSQQLAFDHQEAQQFFDQRLSSPiEAAESSRLCDDVEGWATALQLIALSARQNNSSLHDsarrlagi 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616  222 ------EYLQHELLDELPPPLADAARALAWLPQVGLELFRRLFEElPHG---LDDLLARGFPL--LADANQRYSLPP--- 287
Cdd:PRK04841 247 nashlsDYLVEEVLDNVDLETRHFLLRCSVLRSMNDALIVRVTGE-ENGqmrLEELERQGLFIqrMDDSGEWFRYHPlfa 325

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616  288 ---AIREAWREAPQRPqrDFHREACEWFAEHGETREAVDQALAADEPETAAGLLQ------------KLTEEQLlhghni 352
Cdd:PRK04841 326 sflRHRCQWELAQELP--ELHRAAAEAWLAQGFPSEAIHHALAAGDAQLLRDILLqhgwslfnqgelSLLEECL------ 397

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616  353 gmvlalrDELPAALLASTPRLVILNAWTLLYAGRLAEAEDCIGQLARFLPMPSASRQRVLLAQWQGLFGILLHCRGERGA 432
Cdd:PRK04841 398 -------NALPWEVLLENPRLVLLQAWLAQSQHRYSEVNTLLARAEQELKDRNIELDGTLQAEFNALRAQVAINDGDPEE 470

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616  433 ADYL-REALEQLPEDAWSQGLICRSALMQLAMIEGRMDQARLIGRDALRLAREHDSlifealieLERAQW-LEQRGELLR 510
Cdd:PRK04841 471 AERLaELALAELPLTWYYSRIVATSVLGEVHHCKGELARALAMMQQTEQMARQHDV--------YHYALWsLLQQSEILF 542

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616  511 AEGVL-------DRAQRYLEDLGQQGSPMLGRIALRRARLCLQQGREVEAGHWYRLGLEqARENLDP-WALYGYLGLALL 582
Cdd:PRK04841 543 AQGFLqaayetqEKAFQLIEEQHLEQLPMHEFLLRIRAQLLWEWARLDEAEQCARKGLE-VLSNYQPqQQLQCLAMLAKI 621

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616  583 EAGQGDLDAAFNRLLEVERLMQQ-RHVPDPLYRGALLLV----------SSALTLQQG-RPAQAREillrvraYFQPGRA 650
Cdd:PRK04841 622 SLARGDLDNARRYLNRLENLLGNgRYHSDWIANADKVRLiywqmtgdkeAAANWLRQApKPEFANN-------HFLQGQW 694

                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616  651 RlsppsepelearvehQLALAELYSGEAAAAEARLRGLLAILEAQG------RQTLLCevrmgiAECQFLSGQLPQAQQT 724
Cdd:PRK04841 695 R---------------NIARAQILLGQFDEAEIILEELNENARSLRlmsdlnRNLILL------NQLYWQQGRKSEAQRV 753

                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616  725 LRSGLELAERLG-------------------LQLP----------QRRLRDRQPQ---LFAALPGEEEEGL--------- 763
Cdd:PRK04841 754 LLEALKLANRTGfishfviegeamaqqlrqlIQLNtlpeleqhraQRILREINQHhrhKFAHFDEAFVEKLlnhpdvpel 833

                        890       900       910       920       930       940
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15598616  764 ---SPLSCRELAVLGLIAQGCSNQEIGEQLFISLHTVKTHARRINGKLGVARRTQAVARAKAL 823
Cdd:PRK04841 834 irtSPLTQREWQVLGLIYSGYSNEQIAGELDVAATTIKTHIRNLYQKLGIAHRQEAVQHAQDL 896
 
Name Accession Description Interval E-value
PRK04841 PRK04841
HTH-type transcriptional regulator MalT;
12-823 4.46e-27

HTH-type transcriptional regulator MalT;


Pssm-ID: 235315 [Multi-domain]  Cd Length: 903  Bit Score: 118.12  E-value: 4.46e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616   12 PRLPPQHLPRPRLHQPLLRGEC-RLRLLCAPAGSGKTVLLGECARRAPpgvQVVWLALGGEALDPATFRRRLAGAL---- 86
Cdd:PRK04841  10 PVRLHNTVVRERLLAKLSGANNyRLVLVTSPAGYGKTTLISQWAAGKN---NLGWYSLDESDNQPERFASYLIAALqqat 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616   87 -GLPEDSDE--------------AQLCRRLRN-ASALWLLLDDYPRHPDPALDACLDRLLSAASPRVGWWLASRRRPQCN 150
Cdd:PRK04841  87 nGHCSKSEAlaqkrqyaslsslfAQLFIELADwHQPLYLVIDDYHLITNPEIHEAMRFFLRHQPENLTLVVLSRNLPPLG 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616  151 LARLLLEGELLEVDGGLLAFDADEVAELLRLHGRSA-DAATAGTLLERSGGWCAALRLRLLVGEETAGPLLQ-------- 221
Cdd:PRK04841 167 IANLRVRDQLLEIGSQQLAFDHQEAQQFFDQRLSSPiEAAESSRLCDDVEGWATALQLIALSARQNNSSLHDsarrlagi 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616  222 ------EYLQHELLDELPPPLADAARALAWLPQVGLELFRRLFEElPHG---LDDLLARGFPL--LADANQRYSLPP--- 287
Cdd:PRK04841 247 nashlsDYLVEEVLDNVDLETRHFLLRCSVLRSMNDALIVRVTGE-ENGqmrLEELERQGLFIqrMDDSGEWFRYHPlfa 325

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616  288 ---AIREAWREAPQRPqrDFHREACEWFAEHGETREAVDQALAADEPETAAGLLQ------------KLTEEQLlhghni 352
Cdd:PRK04841 326 sflRHRCQWELAQELP--ELHRAAAEAWLAQGFPSEAIHHALAAGDAQLLRDILLqhgwslfnqgelSLLEECL------ 397

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616  353 gmvlalrDELPAALLASTPRLVILNAWTLLYAGRLAEAEDCIGQLARFLPMPSASRQRVLLAQWQGLFGILLHCRGERGA 432
Cdd:PRK04841 398 -------NALPWEVLLENPRLVLLQAWLAQSQHRYSEVNTLLARAEQELKDRNIELDGTLQAEFNALRAQVAINDGDPEE 470

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616  433 ADYL-REALEQLPEDAWSQGLICRSALMQLAMIEGRMDQARLIGRDALRLAREHDSlifealieLERAQW-LEQRGELLR 510
Cdd:PRK04841 471 AERLaELALAELPLTWYYSRIVATSVLGEVHHCKGELARALAMMQQTEQMARQHDV--------YHYALWsLLQQSEILF 542

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616  511 AEGVL-------DRAQRYLEDLGQQGSPMLGRIALRRARLCLQQGREVEAGHWYRLGLEqARENLDP-WALYGYLGLALL 582
Cdd:PRK04841 543 AQGFLqaayetqEKAFQLIEEQHLEQLPMHEFLLRIRAQLLWEWARLDEAEQCARKGLE-VLSNYQPqQQLQCLAMLAKI 621

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616  583 EAGQGDLDAAFNRLLEVERLMQQ-RHVPDPLYRGALLLV----------SSALTLQQG-RPAQAREillrvraYFQPGRA 650
Cdd:PRK04841 622 SLARGDLDNARRYLNRLENLLGNgRYHSDWIANADKVRLiywqmtgdkeAAANWLRQApKPEFANN-------HFLQGQW 694

                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616  651 RlsppsepelearvehQLALAELYSGEAAAAEARLRGLLAILEAQG------RQTLLCevrmgiAECQFLSGQLPQAQQT 724
Cdd:PRK04841 695 R---------------NIARAQILLGQFDEAEIILEELNENARSLRlmsdlnRNLILL------NQLYWQQGRKSEAQRV 753

                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616  725 LRSGLELAERLG-------------------LQLP----------QRRLRDRQPQ---LFAALPGEEEEGL--------- 763
Cdd:PRK04841 754 LLEALKLANRTGfishfviegeamaqqlrqlIQLNtlpeleqhraQRILREINQHhrhKFAHFDEAFVEKLlnhpdvpel 833

                        890       900       910       920       930       940
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15598616  764 ---SPLSCRELAVLGLIAQGCSNQEIGEQLFISLHTVKTHARRINGKLGVARRTQAVARAKAL 823
Cdd:PRK04841 834 irtSPLTQREWQVLGLIYSGYSNEQIAGELDVAATTIKTHIRNLYQKLGIAHRQEAVQHAQDL 896
GerE COG5905
Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell ...
 764-826 1.44e-19

Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell division, chromosome partitioning, Transcription];


Pssm-ID: 444607 [Multi-domain]  Cd Length: 76  Bit Score: 83.47  E-value: 1.44e-19
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15598616 764 SPLSCRELAVLGLIAQGCSNQEIGEQLFISLHTVKTHARRINGKLGVARRTQAVARAKALGLL 826
Cdd:COG5905  11 SLLTKREREVLELLAEGLTNKEIARQLFISEKTVKNHVSNILRKLGVRNRVQAVVWALRLGLL 73
HTH_LUXR smart00421
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon
 763-820 4.05e-18

helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon


Pssm-ID: 197715 [Multi-domain]  Cd Length: 58  Bit Score: 78.72  E-value: 4.05e-18
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 15598616    763 LSPLSCRELAVLGLIAQGCSNQEIGEQLFISLHTVKTHARRINGKLGVARRTQAVARA 820
Cdd:smart00421   1 LASLTPREREVLRLLAEGLTNKEIAERLGISEKTVKTHLSNIMRKLGVRSRTQAVRLA 58
LuxR_C_like cd06170
C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix ...
 766-820 9.15e-16

C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many are active as homodimers. Many are two domain proteins in which the DNA binding property of the C-terminal DNA binding domain is modulated by modifications of the N-terminal domain. For example in the case of Lux R which participates in the regulation of gene expression in response to fluctuations in cell-population density (quorum-sensing), a signaling molecule, the pheromone Acyl HSL (N-acyl derivatives of homoserine lactone), binds to the N-terminal domain and leads to LuxR dimerization. For others phophorylation of the N-terminal domain leads to multimerization, for example Escherichia coli NarL and Sinorhizobium melilot FixJ. NarL controls gene expression of many respiratory-related operons when environmental nitrate or nitrite is present under anerobic conditions. FixJ is involved in the transcriptional activation of nitrogen fixation genes. The group also includes small proteins which lack an N-terminal signaling domain, such as Bacillus subtilis GerE. GerE is dimeric and acts in conjunction with sigmaK as an activator or a repressor modulating the expression of various genes in particular those encoding the spore-coat. These LuxR family regulators may share a similar organization of their target binding sites. For example the LuxR dimer binds the lux box, a 20bp inverted repeat, GerE dimers bind two 12bp consensus sequences in inverted orientation having the central four bases overlap, and the NarL dimer binds two 7bp inverted repeats separated by 2 bp.


Pssm-ID: 99777 [Multi-domain]  Cd Length: 57  Bit Score: 72.18  E-value: 9.15e-16
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*
gi 15598616 766 LSCRELAVLGLIAQGCSNQEIGEQLFISLHTVKTHARRINGKLGVARRTQAVARA 820
Cdd:cd06170   1 LTPREREVLRLLAEGKTNKEIADILGISEKTVKTHLRNIMRKLGVKSRTQLVAYA 55
GerE pfam00196
Bacterial regulatory proteins, luxR family;
764-820 1.11e-14

Bacterial regulatory proteins, luxR family;


Pssm-ID: 425517 [Multi-domain]  Cd Length: 57  Bit Score: 68.77  E-value: 1.11e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 15598616   764 SPLSCRELAVLGLIAQGCSNQEIGEQLFISLHTVKTHARRINGKLGVARRTQAVARA 820
Cdd:pfam00196   1 DSLSPREREVLRWLAAGKSNKEIADELGISEKTVKVHRSNIMRKLNVHSRVELVRMA 57
 
Name Accession Description Interval E-value
PRK04841 PRK04841
HTH-type transcriptional regulator MalT;
12-823 4.46e-27

HTH-type transcriptional regulator MalT;


Pssm-ID: 235315 [Multi-domain]  Cd Length: 903  Bit Score: 118.12  E-value: 4.46e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616   12 PRLPPQHLPRPRLHQPLLRGEC-RLRLLCAPAGSGKTVLLGECARRAPpgvQVVWLALGGEALDPATFRRRLAGAL---- 86
Cdd:PRK04841  10 PVRLHNTVVRERLLAKLSGANNyRLVLVTSPAGYGKTTLISQWAAGKN---NLGWYSLDESDNQPERFASYLIAALqqat 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616   87 -GLPEDSDE--------------AQLCRRLRN-ASALWLLLDDYPRHPDPALDACLDRLLSAASPRVGWWLASRRRPQCN 150
Cdd:PRK04841  87 nGHCSKSEAlaqkrqyaslsslfAQLFIELADwHQPLYLVIDDYHLITNPEIHEAMRFFLRHQPENLTLVVLSRNLPPLG 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616  151 LARLLLEGELLEVDGGLLAFDADEVAELLRLHGRSA-DAATAGTLLERSGGWCAALRLRLLVGEETAGPLLQ-------- 221
Cdd:PRK04841 167 IANLRVRDQLLEIGSQQLAFDHQEAQQFFDQRLSSPiEAAESSRLCDDVEGWATALQLIALSARQNNSSLHDsarrlagi 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616  222 ------EYLQHELLDELPPPLADAARALAWLPQVGLELFRRLFEElPHG---LDDLLARGFPL--LADANQRYSLPP--- 287
Cdd:PRK04841 247 nashlsDYLVEEVLDNVDLETRHFLLRCSVLRSMNDALIVRVTGE-ENGqmrLEELERQGLFIqrMDDSGEWFRYHPlfa 325

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616  288 ---AIREAWREAPQRPqrDFHREACEWFAEHGETREAVDQALAADEPETAAGLLQ------------KLTEEQLlhghni 352
Cdd:PRK04841 326 sflRHRCQWELAQELP--ELHRAAAEAWLAQGFPSEAIHHALAAGDAQLLRDILLqhgwslfnqgelSLLEECL------ 397

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616  353 gmvlalrDELPAALLASTPRLVILNAWTLLYAGRLAEAEDCIGQLARFLPMPSASRQRVLLAQWQGLFGILLHCRGERGA 432
Cdd:PRK04841 398 -------NALPWEVLLENPRLVLLQAWLAQSQHRYSEVNTLLARAEQELKDRNIELDGTLQAEFNALRAQVAINDGDPEE 470

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616  433 ADYL-REALEQLPEDAWSQGLICRSALMQLAMIEGRMDQARLIGRDALRLAREHDSlifealieLERAQW-LEQRGELLR 510
Cdd:PRK04841 471 AERLaELALAELPLTWYYSRIVATSVLGEVHHCKGELARALAMMQQTEQMARQHDV--------YHYALWsLLQQSEILF 542

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616  511 AEGVL-------DRAQRYLEDLGQQGSPMLGRIALRRARLCLQQGREVEAGHWYRLGLEqARENLDP-WALYGYLGLALL 582
Cdd:PRK04841 543 AQGFLqaayetqEKAFQLIEEQHLEQLPMHEFLLRIRAQLLWEWARLDEAEQCARKGLE-VLSNYQPqQQLQCLAMLAKI 621

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616  583 EAGQGDLDAAFNRLLEVERLMQQ-RHVPDPLYRGALLLV----------SSALTLQQG-RPAQAREillrvraYFQPGRA 650
Cdd:PRK04841 622 SLARGDLDNARRYLNRLENLLGNgRYHSDWIANADKVRLiywqmtgdkeAAANWLRQApKPEFANN-------HFLQGQW 694

                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616  651 RlsppsepelearvehQLALAELYSGEAAAAEARLRGLLAILEAQG------RQTLLCevrmgiAECQFLSGQLPQAQQT 724
Cdd:PRK04841 695 R---------------NIARAQILLGQFDEAEIILEELNENARSLRlmsdlnRNLILL------NQLYWQQGRKSEAQRV 753

                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616  725 LRSGLELAERLG-------------------LQLP----------QRRLRDRQPQ---LFAALPGEEEEGL--------- 763
Cdd:PRK04841 754 LLEALKLANRTGfishfviegeamaqqlrqlIQLNtlpeleqhraQRILREINQHhrhKFAHFDEAFVEKLlnhpdvpel 833

                        890       900       910       920       930       940
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15598616  764 ---SPLSCRELAVLGLIAQGCSNQEIGEQLFISLHTVKTHARRINGKLGVARRTQAVARAKAL 823
Cdd:PRK04841 834 irtSPLTQREWQVLGLIYSGYSNEQIAGELDVAATTIKTHIRNLYQKLGIAHRQEAVQHAQDL 896
GerE COG5905
Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell ...
 764-826 1.44e-19

Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell division, chromosome partitioning, Transcription];


Pssm-ID: 444607 [Multi-domain]  Cd Length: 76  Bit Score: 83.47  E-value: 1.44e-19
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15598616 764 SPLSCRELAVLGLIAQGCSNQEIGEQLFISLHTVKTHARRINGKLGVARRTQAVARAKALGLL 826
Cdd:COG5905  11 SLLTKREREVLELLAEGLTNKEIARQLFISEKTVKNHVSNILRKLGVRNRVQAVVWALRLGLL 73
CitB COG2197
DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal ...
 766-826 6.86e-19

DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 441799 [Multi-domain]  Cd Length: 131  Bit Score: 83.40  E-value: 6.86e-19
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15598616 766 LSCRELAVLGLIAQGCSNQEIGEQLFISLHTVKTHARRINGKLGVARRTQAVARAKALGLL 826
Cdd:COG2197  70 LTPREREVLRLLAEGLSNKEIAERLGISERTVKTHVSNILRKLGVRNRTELVLLALRLGLL 130
HTH_LUXR smart00421
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon
 763-820 4.05e-18

helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon


Pssm-ID: 197715 [Multi-domain]  Cd Length: 58  Bit Score: 78.72  E-value: 4.05e-18
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 15598616    763 LSPLSCRELAVLGLIAQGCSNQEIGEQLFISLHTVKTHARRINGKLGVARRTQAVARA 820
Cdd:smart00421   1 LASLTPREREVLRLLAEGLTNKEIAERLGISEKTVKTHLSNIMRKLGVRSRTQAVRLA 58
LuxR_C_like cd06170
C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix ...
 766-820 9.15e-16

C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many are active as homodimers. Many are two domain proteins in which the DNA binding property of the C-terminal DNA binding domain is modulated by modifications of the N-terminal domain. For example in the case of Lux R which participates in the regulation of gene expression in response to fluctuations in cell-population density (quorum-sensing), a signaling molecule, the pheromone Acyl HSL (N-acyl derivatives of homoserine lactone), binds to the N-terminal domain and leads to LuxR dimerization. For others phophorylation of the N-terminal domain leads to multimerization, for example Escherichia coli NarL and Sinorhizobium melilot FixJ. NarL controls gene expression of many respiratory-related operons when environmental nitrate or nitrite is present under anerobic conditions. FixJ is involved in the transcriptional activation of nitrogen fixation genes. The group also includes small proteins which lack an N-terminal signaling domain, such as Bacillus subtilis GerE. GerE is dimeric and acts in conjunction with sigmaK as an activator or a repressor modulating the expression of various genes in particular those encoding the spore-coat. These LuxR family regulators may share a similar organization of their target binding sites. For example the LuxR dimer binds the lux box, a 20bp inverted repeat, GerE dimers bind two 12bp consensus sequences in inverted orientation having the central four bases overlap, and the NarL dimer binds two 7bp inverted repeats separated by 2 bp.


Pssm-ID: 99777 [Multi-domain]  Cd Length: 57  Bit Score: 72.18  E-value: 9.15e-16
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*
gi 15598616 766 LSCRELAVLGLIAQGCSNQEIGEQLFISLHTVKTHARRINGKLGVARRTQAVARA 820
Cdd:cd06170   1 LTPREREVLRLLAEGKTNKEIADILGISEKTVKTHLRNIMRKLGVKSRTQLVAYA 55
GerE pfam00196
Bacterial regulatory proteins, luxR family;
764-820 1.11e-14

Bacterial regulatory proteins, luxR family;


Pssm-ID: 425517 [Multi-domain]  Cd Length: 57  Bit Score: 68.77  E-value: 1.11e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 15598616   764 SPLSCRELAVLGLIAQGCSNQEIGEQLFISLHTVKTHARRINGKLGVARRTQAVARA 820
Cdd:pfam00196   1 DSLSPREREVLRWLAAGKSNKEIADELGISEKTVKVHRSNIMRKLNVHSRVELVRMA 57
MalT COG2909
ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription];
717-827 3.22e-14

ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription];


Pssm-ID: 442153 [Multi-domain]  Cd Length: 184  Bit Score: 71.66  E-value: 3.22e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616 717 QLPQAQQTLRSGLELAERLGLQLPQRRLRDRQPQLFAAlpgeeeeglsplscRELAVLGLIAQGCSNQEIGEQLFISLHT 796
Cdd:COG2909  88 DPEEALALLERLLALAEAAGRLLLRALALRALGDREEA--------------LAALRRRLLAEGLSNKEIAERLFISVNT 153

                        90       100       110
                ....*....|....*....|....*....|.
gi 15598616 797 VKTHARRINGKLGVARRTQAVARAKALGLLA 827
Cdd:COG2909 154 VKTHLRNIYRKLGVRSRTEAVARARELGLLA 184
CsgD COG2771
DNA-binding transcriptional regulator, CsgD family [Transcription];
639-826 3.94e-10

DNA-binding transcriptional regulator, CsgD family [Transcription];


Pssm-ID: 442052 [Multi-domain]  Cd Length: 188  Bit Score: 60.15  E-value: 3.94e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616 639 LRVRAYFQPGRARLSPPSEPELEARVEHQLALAELYSGEAAAAEARLRGLLAILEAQGRQTLLCEVRMGIAECQFLSGQL 718
Cdd:COG2771   1 LLLLALALLLLALLLLLLALLALLLLLLLAALLLLLALLLLAALLLLAAAAAALAAALAAALLLGLLLLLLIALLLLLLL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616 719 PQAQQTLRSGLELAERLGLQLPQRRLRDRQPQLFAALPGEEEEGLSPLSCRELAVLGLIAQGCSNQEIGEQLFISLHTVK 798
Cdd:COG2771  81 LLALLLLLALLALLAALLARLAALLLALALAALLLAALARLLARAPGLTPREREVLRLLAEGLTLKEIARILGISERTVR 160

                       170       180
                ....*....|....*....|....*...
gi 15598616 799 THARRINGKLGVARRTQAVARAKALGLL 826
Cdd:COG2771 161 THLKRIYRKLGVSSRAELVALALRLGLI 188
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 432-736 6.50e-10

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 61.56  E-value: 6.50e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616   432 AADYLREALEQLPEDAWSQGLICRSALMQLAMIEGRMDQARLIGRDALRLAREHDSLIFEALIELERAQWLEQRGELLRA 511
Cdd:pfam17874  20 ALELAEQALALLPEDDLLARGLATFVLGEAYLCLGDLDAALQAMREAEALARRADSPHVTLWALLQQGEILRAQGRLHQA 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616   512 EGVLDRAQRYLEDLGQQGSPMLGRIALRRARLCLQQGREVEAGHWYRLGLEQARENLDPWALYGYLGLALLEAGQGDLDA 591
Cdd:pfam17874 100 LETYQQALQLARDHGLQHLPLHGFLLVGLADLLYEWNDLEEAEQHAQQGIQLGRQWEPDAAVDAYVLLARIALAQGELEE 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616   592 AFNRLLEVERLMQQRHVPDPLyRGALLLVSSALTLQQGRPAQAREILlrvRAYFQPgrarlSPPSEPELEARVeHQLALA 671
Cdd:pfam17874 180 ALTLLRRAELLARQSFFHVDW-LANAERVRVRLWLARGDLRAAVRWL---RAAEPP-----SDADNHFLEREL-RNLARV 249

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15598616   672 ELYSGEAAAAEARLRGLLAILEAQGRQTLLCEVRMGIAECQFLSGQLPQAQQTLRSGLELAERLG 736
Cdd:pfam17874 250 LLALGRFDDALSLLERLQNLAEQLGRVRSLIENLILQALALLALGRPDEALQALLDALSLAEPEG 314
PRK09935 PRK09935
fimbriae biosynthesis transcriptional regulator FimZ;
765-826 3.31e-08

fimbriae biosynthesis transcriptional regulator FimZ;


Pssm-ID: 182154 [Multi-domain]  Cd Length: 210  Bit Score: 54.88  E-value: 3.31e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15598616  765 PLSCRELAVLGLIAQGCSNQEIGEQLFISLHTVKTHARRINGKLGVARRTQAVARAKALGLL 826
Cdd:PRK09935 149 VLSNREVTILRYLVSGLSNKEIADQLLLSNKTVSAHKSNIYGKLGLHSIVELIDYAKLHELL 210
FixJ COG4566
DNA-binding response regulator, FixJ family, consists of REC and HTH domains [Signal ...
 730-824 1.09e-07

DNA-binding response regulator, FixJ family, consists of REC and HTH domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 443623 [Multi-domain]  Cd Length: 196  Bit Score: 52.80  E-value: 1.09e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616 730 ELAERL--GLQLPQRRLRDRQPQLFAAlpgeeeEGLSPLSCRELAVLGLIAQGCSNQEIGEQLFISLHTVKTHARRINGK 807
Cdd:COG4566 106 ALLDAVrrALARDRARRAERARRAELR------ARLASLTPREREVLDLVVAGLSNKQIARELGISPRTVEVHRANVMEK 179

                        90
                ....*....|....*..
gi 15598616 808 LGVARRTQAVARAKALG 824
Cdd:COG4566 180 LGARSLAELVRLALALG 196
PRK10100 PRK10100
transcriptional regulator CsgD;
764-820 1.53e-07

transcriptional regulator CsgD;


Pssm-ID: 182241 [Multi-domain]  Cd Length: 216  Bit Score: 52.95  E-value: 1.53e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 15598616  764 SPLSCRELAVLGLIAQGCSNQEIGEQLFISLHTVKTHARRINGKLGVARRTQAVARA 820
Cdd:PRK10100 154 ALLTHREKEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWA 210
PRK15369 PRK15369
two component system response regulator;
750-826 7.91e-07

two component system response regulator;


Pssm-ID: 185267 [Multi-domain]  Cd Length: 211  Bit Score: 50.46  E-value: 7.91e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15598616  750 QLFAALPGEEEEGLSPLSCRELAVLGLIAQGCSNQEIGEQLFISLHTVKTHARRINGKLGVARRTQAVARAKALGLL 826
Cdd:PRK15369 134 EAILALLNADDTNPPLLTPRERQILKLITEGYTNRDIAEQLSISIKTVETHRLNMMRKLDVHKVAELLNWARRLGLI 210
PRK10403 PRK10403
nitrate/nitrite response regulator protein NarP;
741-816 4.72e-06

nitrate/nitrite response regulator protein NarP;


Pssm-ID: 182431 [Multi-domain]  Cd Length: 215  Bit Score: 48.31  E-value: 4.72e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15598616  741 QRRLRDRQPQlfaalpGEEEEGLSPLSCRELAVLGLIAQGCSNQEIGEQLFISLHTVKTHARRINGKLGVARRTQA 816
Cdd:PRK10403 135 NQYLREREMF------GAEEDPFSVLTERELDVLHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNVRSRVAA 204
PRK10651 PRK10651
transcriptional regulator NarL; Provisional
 749-816 1.87e-05

transcriptional regulator NarL; Provisional


Pssm-ID: 182619 [Multi-domain]  Cd Length: 216  Bit Score: 46.56  E-value: 1.87e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15598616  749 PQLFAALPGEEEEG---LSPLSCRELAVLGLIAQGCSNQEIGEQLFISLHTVKTHARRINGKLGVARRTQA 816
Cdd:PRK10651 136 PVLAASLRANRATTerdVNQLTPRERDILKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEA 206
PRK09958 PRK09958
acid-sensing system DNA-binding response regulator EvgA;
759-809 3.19e-04

acid-sensing system DNA-binding response regulator EvgA;


Pssm-ID: 182168 [Multi-domain]  Cd Length: 204  Bit Score: 42.96  E-value: 3.19e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 15598616  759 EEEGLSPLSCRELAVLGLIAQGCSNQEIGEQLFISLHTVKTHARRINGKLG 809
Cdd:PRK09958 137 DQQKLDSLSKQEISVMRYILDGKDNNDIAEKMFISNKTVSTYKSRLMEKLE 187
COG3903 COG3903
Predicted ATPase [General function prediction only];
315-686 1.00e-03

Predicted ATPase [General function prediction only];


Pssm-ID: 443109 [Multi-domain]  Cd Length: 933  Bit Score: 42.70  E-value: 1.00e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616 315 HGETREAVDQALAADEPETAAGLLQKLTEEQLLHGHNIGMVLALRDELPAALLASTPRLVILNAWTLLYAGRLAEAEDCI 394
Cdd:COG3903 561 LREGRRWLERALAAAGEAAAALAAAAALAAAAAAARAAAAAAAAAAAAAAAAAAAAAAAAAALLLLAALAAAAAAAAAAA 640

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616 395 GQLARFLPMPSASRQRVLLAQWQGLFGILLHCRGERGAADYLREALEQLPEDAWSQGLICRSALMQLAMIEGRMDQARLI 474
Cdd:COG3903 641 AAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAAAAAAAALAAAAAALAAAAAAAALAAAAAAALAAAAAAAAA 720

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616 475 GRDALRLAREHDSLIFEALIELERAQWLEQRGELLRAEGVLDRAQRYLEDLGQQGSPMLGRIALRRARLCLQQGREVEAG 554
Cdd:COG3903 721 AAAAAALLAAAAAAALAAAAAAAALALAAAAAAAAAAAAAAALAAAAAAAALAALLLALAAAAAALAAAAAAAAAAAAAA 800

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616 555 HWYRLGLEQARENLDPWALYGYLGLALLEAGQGDLDAAFNRLLEVERLMQQRHVPDPLYRGALLLVSSALTLQQGRPAQA 634
Cdd:COG3903 801 AAAAAAAAAAAAAAALAAAAAAAAAAAAALAAALAAAAAAAAAAAAAAAAAAALAAALAAAAAAAAAAALAAAAAAAAAA 880

                       330       340       350       360       370
                ....*....|....*....|....*....|....*....|....*....|..
gi 15598616 635 REILLRVRAYFQPGRARLSPPSEPELEARVEHQLALAELYSGEAAAAEARLR 686
Cdd:COG3903 881 AAALLAAAAAAAAAAAAAAAAAAALAAAAAAAAAAALAAAAAAAAAAAAAAA 932
MalT COG2909
ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription];
108-257 1.19e-03

ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription];


Pssm-ID: 442153 [Multi-domain]  Cd Length: 184  Bit Score: 40.84  E-value: 1.19e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616 108 WLLLDDYPRhpdpALDACLDRLLSAASPRVGWWLASRRRPQCNLArlllegELLEVDGGLLAfdADEVAELLRLHGRSAD 187
Cdd:COG2909   1 ALVLDDYHL----IDDIHLAFLLRHLPPNLHLVLASRTDPLARLR------ARLELRADDLR--REEAAALLRRRLLPLS 68

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616 188 AATAGTLLERSGGWcAALRLRLlvgeETAGPLLQEYLQHELLDELPPPLADAARALAWLPQVGLELFRRL 257
Cdd:COG2909  69 EEDAARLAERTEGW-ARLALDP----EEALALLERLLALAEAAGRLLLRALALRALGDREEALAALRRRL 133
COG3903 COG3903
Predicted ATPase [General function prediction only];
81-540 4.00e-03

Predicted ATPase [General function prediction only];


Pssm-ID: 443109 [Multi-domain]  Cd Length: 933  Bit Score: 40.77  E-value: 4.00e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616  81 RLAGALGLPEDSDEAQLCRRLRNASALWLLLDDYPRHPDPALDACLDRLLSAASPRVGWWLASRRRPQCNLARLLLEGEL 160
Cdd:COG3903 474 REYAAERLAEAGERAAARRRHADYYLALAERAAAELRGPDQLAWLARLDAEHDNLRAALRWALAHGDAELALRLAAALAP 553

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616 161 LEVDGGLLAFDADEVAELLRLHGRSADAATAGTLLERSGGWCAALRLRLLVGEETAGPLLQEYLQHELLDELPPPLADAA 240
Cdd:COG3903 554 FWFLRGLLREGRRWLERALAAAGEAAAALAAAAALAAAAAAARAAAAAAAAAAAAAAAAAAAAAAAAAALLLLAALAAAA 633

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616 241 RALAWLPQVGLELFRRLFEELPHGLDDLLARGFPLLADANQRYSLPPAIREAWREAPQRPQRDFHREACEWFAEHGETRE 320
Cdd:COG3903 634 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAAAAAAAALAAAAAALAAAAAAAALAAAAAAALAA 713

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616 321 AVDQALAADEPETAAGLLQKLTEEQLLHGHNIGMVLALRDELPAALLASTPRLVILNAWTLLYAGRLAEAEDCIGQLARF 400
Cdd:COG3903 714 AAAAAAAAAAAAALLAAAAAAALAAAAAAAALALAAAAAAAAAAAAAAALAAAAAAAALAALLLALAAAAAALAAAAAAA 793

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616 401 LPMPSASRQRVLLAQWQGLFGILLHCRGERGAADYLREALEQLPEDAWSQGLICRSALMQLAMIEGRMDQARLIGRDALR 480
Cdd:COG3903 794 AAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAALAAALAAAAAAAAAAAAAAAAAAALAAALAAAAAAAAAAALAAA 873

                       410       420       430       440       450       460
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616 481 LAREHDSLIFEALIELERAQWLEQRGELLRAEGVLDRAQRYLEDLGQQGSPMLGRIALRR 540
Cdd:COG3903 874 AAAAAAAAAALLAAAAAAAAAAAAAAAAAAALAAAAAAAAAAALAAAAAAAAAAAAAAAA 933
COG3903 COG3903
Predicted ATPase [General function prediction only];
357-761 4.21e-03

Predicted ATPase [General function prediction only];


Pssm-ID: 443109 [Multi-domain]  Cd Length: 933  Bit Score: 40.77  E-value: 4.21e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616 357 ALRDELPAALLASTPRLVILNAWTLLYAGRLAEAEDCIGQLARFLPmpsaSRQRVLLAQWQGLFGILLHCRGERGAADYL 436
Cdd:COG3903 531 ALRWALAHGDAELALRLAAALAPFWFLRGLLREGRRWLERALAAAG----EAAAALAAAAALAAAAAAARAAAAAAAAAA 606

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616 437 REALEQLPEDAWSQGLICRSALMQLAMIEGRMDQARLIGRDALRLAREHDSLIFEALIELERAQWLEQRGELLRAEGVLD 516
Cdd:COG3903 607 AAAAAAAAAAAAAAAALLLLAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAAAAAAAA 686

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616 517 RAQRYLEDLGQQGSPMLGRIALRRARLCLQQGREVEAGHWYRLGLEQARENLDPWALYGYLGLALLEAGQGDLDAAFNRL 596
Cdd:COG3903 687 LAAAAAALAAAAAAAALAAAAAAALAAAAAAAAAAAAAAALLAAAAAAALAAAAAAAALALAAAAAAAAAAAAAAALAAA 766

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616 597 LEVERLMQQRHVPDPLYRGALLLVSSALTLQQGRPAQAREILLRVRAYFQPGRARLSPPSEPELEARVEHQLALAELYSG 676
Cdd:COG3903 767 AAAAALAALLLALAAAAAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAALAAALAAAAAAAAAAAA 846

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616 677 EAAAAEARLRGLLAILEAQGRQTLLCEVRMGIAECQFLSGQLPQAQQTLRSGLELAERLGLQLPQRRLRDRQPQLFAALP 756
Cdd:COG3903 847 AAAAAAALAAALAAAAAAAAAAALAAAAAAAAAAAAALLAAAAAAAAAAAAAAAAAAALAAAAAAAAAAALAAAAAAAAA 926


                ....*
gi 15598616 757 GEEEE 761
Cdd:COG3903 927 AAAAA 931
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 37-130 7.13e-03

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 37.74  E-value: 7.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616     37 LLCAPAGSGKTVLLGECARRA-PPGVQVVWLALGGEALDPATFRRRLAGALGLPEDSDE---AQLCRRLRNASALWLLLD 112
Cdd:smart00382   6 LIVGPPGSGKTTLARALARELgPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASGSGElrlRLALALARKLKPDVLILD 85

                           90
                   ....*....|....*...
gi 15598616    113 DYPRHPDPALDACLDRLL 130
Cdd:smart00382  86 EITSLLDAEQEALLLLLE 103
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 432-641 8.97e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 38.94  E-value: 8.97e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616 432 AADYLREALEQLPEDAWSQglicrSALMQLAMIEGRMDQARLIGRDALRLAREHdsliFEALIELeraqwleqrGELLRA 511
Cdd:COG2956  27 AIDLLEEALELDPETVEAH-----LALGNLYRRRGEYDRAIRIHQKLLERDPDR----AEALLEL---------AQDYLK 88

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598616 512 EGVLDRAQRYLEDLgQQGSPMLGRIALRRARLCLQQGREVEAGHWYRLGLEQARENLDPWALYGYLGLAlleagQGDLDA 591
Cdd:COG2956  89 AGLLDRAEELLEKL-LELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLE-----QGDYDE 162

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|
gi 15598616 592 AFNRLLEVERLmqqrhvpDPLYRGALLLVSSALtLQQGRPAQAREILLRV 641
Cdd:COG2956 163 AIEALEKALKL-------DPDCARALLLLAELY-LEQGDYEEAIAALERA 204
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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