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Conserved domains on  [gi|15597766|ref|NP_251260|]
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PA-I galactophilic lectin [Pseudomonas aeruginosa PAO1]

Protein Classification

LecA/PA-IL family lectin( domain architecture ID 10544876)

LecA/PA-IL family lectin such as Pseudomonas aeruginosa PA-I galactophilic lectin that binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl-beta-D-galactoside, and N-acetyl-D-galactosamine

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PA-IL pfam07828
PA-IL-like protein; The members of this family are similar to the galactophilic lectin-1 ...
 2-122 1.47e-73

PA-IL-like protein; The members of this family are similar to the galactophilic lectin-1 expressed by P. aeruginosa (PA-IL). Lectins recognising specific carbohydrates found on the surface of host cells are known to be involved in the initiation of infections by this organizm. The protein is thought to be organized into an extensive network of beta-sheets, as is the case with many other lectins.


:

Pssm-ID: 369543  Cd Length: 121  Bit Score: 214.50  E-value: 1.47e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597766     2 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTG 81
Cdd:pfam07828   1 AWKGEVLANAEAGKSTGIILKPGDTISIVAAGWAKYGPDNKEGAAGDGEHPDNGLICHDAFCAALVAKIANKGFAIGNGG 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 15597766    82 LFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 122
Cdd:pfam07828  81 LFKTVAPNNVDGAIILIFNDVPGTFGDNSGEFQVEIGIDQR 121
 
Name Accession Description Interval E-value
PA-IL pfam07828
PA-IL-like protein; The members of this family are similar to the galactophilic lectin-1 ...
 2-122 1.47e-73

PA-IL-like protein; The members of this family are similar to the galactophilic lectin-1 expressed by P. aeruginosa (PA-IL). Lectins recognising specific carbohydrates found on the surface of host cells are known to be involved in the initiation of infections by this organizm. The protein is thought to be organized into an extensive network of beta-sheets, as is the case with many other lectins.


Pssm-ID: 369543  Cd Length: 121  Bit Score: 214.50  E-value: 1.47e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597766     2 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTG 81
Cdd:pfam07828   1 AWKGEVLANAEAGKSTGIILKPGDTISIVAAGWAKYGPDNKEGAAGDGEHPDNGLICHDAFCAALVAKIANKGFAIGNGG 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 15597766    82 LFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 122
Cdd:pfam07828  81 LFKTVAPNNVDGAIILIFNDVPGTFGDNSGEFQVEIGIDQR 121
 
Name Accession Description Interval E-value
PA-IL pfam07828
PA-IL-like protein; The members of this family are similar to the galactophilic lectin-1 ...
 2-122 1.47e-73

PA-IL-like protein; The members of this family are similar to the galactophilic lectin-1 expressed by P. aeruginosa (PA-IL). Lectins recognising specific carbohydrates found on the surface of host cells are known to be involved in the initiation of infections by this organizm. The protein is thought to be organized into an extensive network of beta-sheets, as is the case with many other lectins.


Pssm-ID: 369543  Cd Length: 121  Bit Score: 214.50  E-value: 1.47e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597766     2 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTG 81
Cdd:pfam07828   1 AWKGEVLANAEAGKSTGIILKPGDTISIVAAGWAKYGPDNKEGAAGDGEHPDNGLICHDAFCAALVAKIANKGFAIGNGG 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 15597766    82 LFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 122
Cdd:pfam07828  81 LFKTVAPNNVDGAIILIFNDVPGTFGDNSGEFQVEIGIDQR 121
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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