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Conserved domains on  [gi|15597700|ref|NP_251194|]
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hypothetical protein PA2504 [Pseudomonas aeruginosa PAO1]

Protein Classification

DUF2185 domain-containing protein( domain architecture ID 10371809)

DUF2185 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF2185 pfam09951
Protein of unknown function (DUF2185); This domain, found in various hypothetical bacterial ...
 115-199 7.45e-41

Protein of unknown function (DUF2185); This domain, found in various hypothetical bacterial proteins, has no known function.


:

Pssm-ID: 462932  Cd Length: 85  Bit Score: 133.51  E-value: 7.45e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597700   115 CFVTRRVIDEGKAVGYLYREAPEEENDSGWRLMAGDESDDYMNTAGTTAYVSLGSVLNADDSILPLLDAPPGRAFERLAD 194
Cdd:pfam09951   1 CIVSDRILVEGEKVGYMYRENPVEENDSGWRFFSGDESDEYMNDPDNFGIYDLNTILNIDPSILPLLDAPIGSAFERDED 80


                  ....*
gi 15597700   195 GSFIE 199
Cdd:pfam09951  81 GEFVE 85
DUF2314 super family cl19625
Uncharacterized protein conserved in bacteria (DUF2314); This domain is found in various ...
 36-96 2.07e-07

Uncharacterized protein conserved in bacteria (DUF2314); This domain is found in various bacterial hypothetical proteins, as well as putative ankyrin repeat proteins. The exact function of the domains comprising this family has not, as yet, been determined.


The actual alignment was detected with superfamily member pfam10077:

Pssm-ID: 473197  Cd Length: 135  Bit Score: 48.12  E-value: 2.07e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15597700    36 SVKLIFAFDTDNPDAPRAERLWVTVegIEADGA-FSGRLDNYPQYIRDLSLGERIVFEARHI 96
Cdd:pfam10077  37 AVKIPFADGSGGEEEPTVEHMWISD--VQFDGGnISGVLGNEPEELTNVKEGDAITVPVDQI 96
 
Name Accession Description Interval E-value
DUF2185 pfam09951
Protein of unknown function (DUF2185); This domain, found in various hypothetical bacterial ...
 115-199 7.45e-41

Protein of unknown function (DUF2185); This domain, found in various hypothetical bacterial proteins, has no known function.


Pssm-ID: 462932  Cd Length: 85  Bit Score: 133.51  E-value: 7.45e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597700   115 CFVTRRVIDEGKAVGYLYREAPEEENDSGWRLMAGDESDDYMNTAGTTAYVSLGSVLNADDSILPLLDAPPGRAFERLAD 194
Cdd:pfam09951   1 CIVSDRILVEGEKVGYMYRENPVEENDSGWRFFSGDESDEYMNDPDNFGIYDLNTILNIDPSILPLLDAPIGSAFERDED 80


                  ....*
gi 15597700   195 GSFIE 199
Cdd:pfam09951  81 GEFVE 85
COG4859 COG4859
Uncharacterized protein, contains DUF2185 domain [Function unknown];
100-205 8.87e-40

Uncharacterized protein, contains DUF2185 domain [Function unknown];


Pssm-ID: 443887  Cd Length: 106  Bit Score: 131.58  E-value: 8.87e-40
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597700 100 EHDPREtpISRYARRCFVTRRVIDEGKAVGYLYREAPEEENDSGWRLMAGDESDDYMNTAGTTAYVSLGSVLNADDSILP 179
Cdd:COG4859   1 MEEIRE--LWEGAGGCIVSDRITVEGEPVGFMYREEPDNEQDSGWRFFSGDETDEYMDDPDNFGIYSLNTILNIDPAIIP 78

                        90       100
                ....*....|....*....|....*..
gi 15597700 180 LLDAPPGRAFERLADGS-FIEVQGPEG 205
Cdd:COG4859  79 LLDAPYGTAFERDEDGNkFVPVEDWEP 105
DUF2314 pfam10077
Uncharacterized protein conserved in bacteria (DUF2314); This domain is found in various ...
 36-96 2.07e-07

Uncharacterized protein conserved in bacteria (DUF2314); This domain is found in various bacterial hypothetical proteins, as well as putative ankyrin repeat proteins. The exact function of the domains comprising this family has not, as yet, been determined.


Pssm-ID: 431035  Cd Length: 135  Bit Score: 48.12  E-value: 2.07e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15597700    36 SVKLIFAFDTDNPDAPRAERLWVTVegIEADGA-FSGRLDNYPQYIRDLSLGERIVFEARHI 96
Cdd:pfam10077  37 AVKIPFADGSGGEEEPTVEHMWISD--VQFDGGnISGVLGNEPEELTNVKEGDAITVPVDQI 96
YegJ COG3779
Uncharacterized conserved protein YegJ, DUF2314 family [Function unknown];
19-96 1.21e-05

Uncharacterized conserved protein YegJ, DUF2314 family [Function unknown];


Pssm-ID: 442993  Cd Length: 158  Bit Score: 43.86  E-value: 1.21e-05
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15597700  19 TFYKPDAETIDRVAAGESVKLIFAfdtdNPDAPRAERLWVTVEGIEADGaFSGRLDNYPQYIRDLSLGERIVFEARHI 96
Cdd:COG3779  46 YFWRELSWEIVPALDLFAVKVAFA----QEDGPGVEHMWITDVNFDGDT-ISGTLANEPGYLTNVRAGDPVSFPRDDI 118
 
Name Accession Description Interval E-value
DUF2185 pfam09951
Protein of unknown function (DUF2185); This domain, found in various hypothetical bacterial ...
 115-199 7.45e-41

Protein of unknown function (DUF2185); This domain, found in various hypothetical bacterial proteins, has no known function.


Pssm-ID: 462932  Cd Length: 85  Bit Score: 133.51  E-value: 7.45e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597700   115 CFVTRRVIDEGKAVGYLYREAPEEENDSGWRLMAGDESDDYMNTAGTTAYVSLGSVLNADDSILPLLDAPPGRAFERLAD 194
Cdd:pfam09951   1 CIVSDRILVEGEKVGYMYRENPVEENDSGWRFFSGDESDEYMNDPDNFGIYDLNTILNIDPSILPLLDAPIGSAFERDED 80


                  ....*
gi 15597700   195 GSFIE 199
Cdd:pfam09951  81 GEFVE 85
COG4859 COG4859
Uncharacterized protein, contains DUF2185 domain [Function unknown];
100-205 8.87e-40

Uncharacterized protein, contains DUF2185 domain [Function unknown];


Pssm-ID: 443887  Cd Length: 106  Bit Score: 131.58  E-value: 8.87e-40
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597700 100 EHDPREtpISRYARRCFVTRRVIDEGKAVGYLYREAPEEENDSGWRLMAGDESDDYMNTAGTTAYVSLGSVLNADDSILP 179
Cdd:COG4859   1 MEEIRE--LWEGAGGCIVSDRITVEGEPVGFMYREEPDNEQDSGWRFFSGDETDEYMDDPDNFGIYSLNTILNIDPAIIP 78

                        90       100
                ....*....|....*....|....*..
gi 15597700 180 LLDAPPGRAFERLADGS-FIEVQGPEG 205
Cdd:COG4859  79 LLDAPYGTAFERDEDGNkFVPVEDWEP 105
DUF2314 pfam10077
Uncharacterized protein conserved in bacteria (DUF2314); This domain is found in various ...
 36-96 2.07e-07

Uncharacterized protein conserved in bacteria (DUF2314); This domain is found in various bacterial hypothetical proteins, as well as putative ankyrin repeat proteins. The exact function of the domains comprising this family has not, as yet, been determined.


Pssm-ID: 431035  Cd Length: 135  Bit Score: 48.12  E-value: 2.07e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15597700    36 SVKLIFAFDTDNPDAPRAERLWVTVegIEADGA-FSGRLDNYPQYIRDLSLGERIVFEARHI 96
Cdd:pfam10077  37 AVKIPFADGSGGEEEPTVEHMWISD--VQFDGGnISGVLGNEPEELTNVKEGDAITVPVDQI 96
YegJ COG3779
Uncharacterized conserved protein YegJ, DUF2314 family [Function unknown];
19-96 1.21e-05

Uncharacterized conserved protein YegJ, DUF2314 family [Function unknown];


Pssm-ID: 442993  Cd Length: 158  Bit Score: 43.86  E-value: 1.21e-05
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15597700  19 TFYKPDAETIDRVAAGESVKLIFAfdtdNPDAPRAERLWVTVEGIEADGaFSGRLDNYPQYIRDLSLGERIVFEARHI 96
Cdd:COG3779  46 YFWRELSWEIVPALDLFAVKVAFA----QEDGPGVEHMWITDVNFDGDT-ISGTLANEPGYLTNVRAGDPVSFPRDDI 118
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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