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Conserved domains on  [gi|15597619|ref|NP_251113|]
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hypothetical protein PA2423 [Pseudomonas aeruginosa PAO1]

Protein Classification

Bro-N domain-containing protein( domain architecture ID 10660100)

Bro-N domain-containing protein may bind DNA to influence host DNA replication and/or transcription

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Bro-N smart01040
BRO family, N-terminal domain; This family includes the N-terminus of baculovirus BRO and ALI ...
 113-198 1.12e-19

BRO family, N-terminal domain; This family includes the N-terminus of baculovirus BRO and ALI motif proteins. The function of BRO proteins is unknown. It has been suggested that BRO-A and BRO-C are DNA binding proteins that influence host DNA replication and/or transcription. This Pfam domain does not include the characteristic invariant alanine, leucine, isoleucine motif of the ALI proteins.


:

Pssm-ID: 214989  Cd Length: 89  Bit Score: 81.08  E-value: 1.12e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597619    113 LRALLIDDQAWFVLDDFARLIEHSQPEQMLARLDDDQARRESLRSERGEDQAQ--WLISESGAYAALIYQQRGDGGELRR 190
Cdd:smart01040   2 VRTVLIDGEPWFVAKDVARALGYSNPRDAIRKLDDDEKRVAGTELLDTLGGKQevRIISESGLYRLIMRSRKPEAKKFRR 81


                   ....*...
gi 15597619    191 WLSGEVVP 198
Cdd:smart01040  82 WVTDEVLP 89
 
Name Accession Description Interval E-value
Bro-N smart01040
BRO family, N-terminal domain; This family includes the N-terminus of baculovirus BRO and ALI ...
 113-198 1.12e-19

BRO family, N-terminal domain; This family includes the N-terminus of baculovirus BRO and ALI motif proteins. The function of BRO proteins is unknown. It has been suggested that BRO-A and BRO-C are DNA binding proteins that influence host DNA replication and/or transcription. This Pfam domain does not include the characteristic invariant alanine, leucine, isoleucine motif of the ALI proteins.


Pssm-ID: 214989  Cd Length: 89  Bit Score: 81.08  E-value: 1.12e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597619    113 LRALLIDDQAWFVLDDFARLIEHSQPEQMLARLDDDQARRESLRSERGEDQAQ--WLISESGAYAALIYQQRGDGGELRR 190
Cdd:smart01040   2 VRTVLIDGEPWFVAKDVARALGYSNPRDAIRKLDDDEKRVAGTELLDTLGGKQevRIISESGLYRLIMRSRKPEAKKFRR 81


                   ....*...
gi 15597619    191 WLSGEVVP 198
Cdd:smart01040  82 WVTDEVLP 89
COG3617 COG3617
Prophage antirepressor [Mobilome: prophages, transposons];
113-201 2.30e-17

Prophage antirepressor [Mobilome: prophages, transposons];


Pssm-ID: 442835  Cd Length: 106  Bit Score: 75.32  E-value: 2.30e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597619 113 LRALLIDDQAWFVLDDFARLIEHSQPEQMLARLDDDQARRESLRSErGEDQAQWLISESGAYAALIYQQRGDGGELRRWL 192
Cdd:COG3617  15 VRTVEIDGEPWFVAKDVARALGYSNPSDALKHLDDDEKTKLELDTP-GGPQEMLFISESGLYRLILRSRKPEAKRFKRWV 93


                ....*....
gi 15597619 193 SGEVVPELR 201
Cdd:COG3617  94 TDEVLPSIR 102
Bro-N pfam02498
BRO family, N-terminal domain; This family includes the N-terminus of baculovirus BRO and ALI ...
 118-198 1.54e-06

BRO family, N-terminal domain; This family includes the N-terminus of baculovirus BRO and ALI motif proteins. The function of BRO proteins is unknown. It has been suggested that BRO-A and BRO-C are DNA binding proteins that influence host DNA replication and/or transcription. This Pfam domain does not include the characteriztic invariant alanine, leucine, isoleucine motif of the ALI proteins.


Pssm-ID: 376797  Cd Length: 96  Bit Score: 45.43  E-value: 1.54e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597619   118 IDDQAWFVLDDFARLIEHSQPEQMLAR-LDDDQAR-------RESLRSERGEDQAQWLISESGAYaALIyqQRGD---GG 186
Cdd:pfam02498   8 ENGEPWFVAKDVAKALGYTNPNKAIKKhVDKANKKclnelvnTLDHEDGKNGHPKTVFINEAGLY-LLI--MRSDkpkAE 84

                          90
                  ....*....|..
gi 15597619   187 ELRRWLSGEVVP 198
Cdd:pfam02498  85 EFRKWVTQEVLP 96
 
Name Accession Description Interval E-value
Bro-N smart01040
BRO family, N-terminal domain; This family includes the N-terminus of baculovirus BRO and ALI ...
 113-198 1.12e-19

BRO family, N-terminal domain; This family includes the N-terminus of baculovirus BRO and ALI motif proteins. The function of BRO proteins is unknown. It has been suggested that BRO-A and BRO-C are DNA binding proteins that influence host DNA replication and/or transcription. This Pfam domain does not include the characteristic invariant alanine, leucine, isoleucine motif of the ALI proteins.


Pssm-ID: 214989  Cd Length: 89  Bit Score: 81.08  E-value: 1.12e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597619    113 LRALLIDDQAWFVLDDFARLIEHSQPEQMLARLDDDQARRESLRSERGEDQAQ--WLISESGAYAALIYQQRGDGGELRR 190
Cdd:smart01040   2 VRTVLIDGEPWFVAKDVARALGYSNPRDAIRKLDDDEKRVAGTELLDTLGGKQevRIISESGLYRLIMRSRKPEAKKFRR 81


                   ....*...
gi 15597619    191 WLSGEVVP 198
Cdd:smart01040  82 WVTDEVLP 89
COG3617 COG3617
Prophage antirepressor [Mobilome: prophages, transposons];
113-201 2.30e-17

Prophage antirepressor [Mobilome: prophages, transposons];


Pssm-ID: 442835  Cd Length: 106  Bit Score: 75.32  E-value: 2.30e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597619 113 LRALLIDDQAWFVLDDFARLIEHSQPEQMLARLDDDQARRESLRSErGEDQAQWLISESGAYAALIYQQRGDGGELRRWL 192
Cdd:COG3617  15 VRTVEIDGEPWFVAKDVARALGYSNPSDALKHLDDDEKTKLELDTP-GGPQEMLFISESGLYRLILRSRKPEAKRFKRWV 93


                ....*....
gi 15597619 193 SGEVVPELR 201
Cdd:COG3617  94 TDEVLPSIR 102
Bro-N pfam02498
BRO family, N-terminal domain; This family includes the N-terminus of baculovirus BRO and ALI ...
 118-198 1.54e-06

BRO family, N-terminal domain; This family includes the N-terminus of baculovirus BRO and ALI motif proteins. The function of BRO proteins is unknown. It has been suggested that BRO-A and BRO-C are DNA binding proteins that influence host DNA replication and/or transcription. This Pfam domain does not include the characteriztic invariant alanine, leucine, isoleucine motif of the ALI proteins.


Pssm-ID: 376797  Cd Length: 96  Bit Score: 45.43  E-value: 1.54e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597619   118 IDDQAWFVLDDFARLIEHSQPEQMLAR-LDDDQAR-------RESLRSERGEDQAQWLISESGAYaALIyqQRGD---GG 186
Cdd:pfam02498   8 ENGEPWFVAKDVAKALGYTNPNKAIKKhVDKANKKclnelvnTLDHEDGKNGHPKTVFINEAGLY-LLI--MRSDkpkAE 84

                          90
                  ....*....|..
gi 15597619   187 ELRRWLSGEVVP 198
Cdd:pfam02498  85 EFRKWVTQEVLP 96
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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