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Conserved domains on  [gi|15597005|ref|NP_250499|]
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ABC transporter permease [Pseudomonas aeruginosa PAO1]

Protein Classification

ABC transporter permease( domain architecture ID 11468042)

ABC transporter permease is the transmembrane subunit (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporters which generally bind type 2 PBPs; similar to microcin C transport system permease protein YejE

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
 1-339 0e+00

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


:

Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 671.48  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005   1 MRLSPINQRRWARFKSNKRGWWSLWLFLILFVGSLGAELIANDKPLVVHYDGGWYFPVFKRYPETTFGGEFPLEANYKSP 80
Cdd:COG4239   2 MRLSPLNRRRWRRFKANRRGYWSLWIFLVLFVLSLFAELIANDKPLLVSYDGELYFPVLKDYPETTFGGDFETEADYRDP 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005  81 YISQLIaEKDGWVLWPPIPYSYDTINYELKVPAPAPPSAENWLGTDDQARDVLARVIYGFRVSILFALTLTVLSSLIGVT 160
Cdd:COG4239  82 FVQELI-EAKGWALWPPIPYSYDTINYDLPSPAPSPPSAENWLGTDDQGRDVLARLIYGFRISVLFGLALTVISSVIGVA 160

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005 161 VGALQGYYGGWVDLLGQRFLEVWSGLPVLYLLIILASFVQPNFWWLLGIMLLFSWMSLVDVVRAEFLRGRNLEYVRAARA 240
Cdd:COG4239 161 AGAVQGYFGGRVDLLFQRFIEIWSSMPELYLLIILSSIFQPSFWLLLGILLLFGWMGLVGVVRAEFLRARNLEYVRAARA 240

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005 241 LGMRNSAIMFRHILPNAMISTLTFMPFILTGAIGTLTSLDFLGFGLPPGAPSLGELVAQGKSNLQAPWLGISAFVVLAVM 320
Cdd:COG4239 241 LGVSDRRIMFRHILPNAMVATLTFLPFILSGAITTLTSLDFLGFGLPPGSPSLGELLAQGKNNLQAPWLGLSAFVVLALM 320

                       330
                ....*....|....*....
gi 15597005 321 LSLLVFIGEAARDAFDPRK 339
Cdd:COG4239 321 LSLLVFIGEAVRDAFDPRK 339
 
Name Accession Description Interval E-value
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
 1-339 0e+00

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 671.48  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005   1 MRLSPINQRRWARFKSNKRGWWSLWLFLILFVGSLGAELIANDKPLVVHYDGGWYFPVFKRYPETTFGGEFPLEANYKSP 80
Cdd:COG4239   2 MRLSPLNRRRWRRFKANRRGYWSLWIFLVLFVLSLFAELIANDKPLLVSYDGELYFPVLKDYPETTFGGDFETEADYRDP 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005  81 YISQLIaEKDGWVLWPPIPYSYDTINYELKVPAPAPPSAENWLGTDDQARDVLARVIYGFRVSILFALTLTVLSSLIGVT 160
Cdd:COG4239  82 FVQELI-EAKGWALWPPIPYSYDTINYDLPSPAPSPPSAENWLGTDDQGRDVLARLIYGFRISVLFGLALTVISSVIGVA 160

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005 161 VGALQGYYGGWVDLLGQRFLEVWSGLPVLYLLIILASFVQPNFWWLLGIMLLFSWMSLVDVVRAEFLRGRNLEYVRAARA 240
Cdd:COG4239 161 AGAVQGYFGGRVDLLFQRFIEIWSSMPELYLLIILSSIFQPSFWLLLGILLLFGWMGLVGVVRAEFLRARNLEYVRAARA 240

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005 241 LGMRNSAIMFRHILPNAMISTLTFMPFILTGAIGTLTSLDFLGFGLPPGAPSLGELVAQGKSNLQAPWLGISAFVVLAVM 320
Cdd:COG4239 241 LGVSDRRIMFRHILPNAMVATLTFLPFILSGAITTLTSLDFLGFGLPPGSPSLGELLAQGKNNLQAPWLGLSAFVVLALM 320

                       330
                ....*....|....*....
gi 15597005 321 LSLLVFIGEAARDAFDPRK 339
Cdd:COG4239 321 LSLLVFIGEAVRDAFDPRK 339
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 2-339 5.96e-177

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 493.73  E-value: 5.96e-177
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005    2 RLSPINQRRWARFKSNKRGWWSLWLFLILFVGSLGAELIANDKPLVVHYDGGWYFPVFKRYPETTFGGEFPLEANYKSPY 81
Cdd:PRK15021   3 RLSPVNQARWARFRHNRRGYWSLWIFLVLFGLSLCSELIANDKPLLVRYDGSWYFPLLKNYSESDFGGPLASQADYQDPW 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005   82 ISQLIaEKDGWVLWPPIPYSYDTINYELKVPAPAPPSAENWLGTDDQARDVLARVIYGFRVSILFALTLTVLSSLIGVTV 161
Cdd:PRK15021  83 LKQRL-ENNGWVLWAPIRFGATSINFATDKPFPSPPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVLA 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005  162 GALQGYYGGWVDLLGQRFLEVWSGLPVLYLLIILASFVQPNFWWLLGIMLLFSWMSLVDVVRAEFLRGRNLEYVRAARAL 241
Cdd:PRK15021 162 GALQGYYGGKVDLWGQRFIEVWSGMPTLFLIILLSSVVQPNFWWLLAITVLFGWMSLVGVVRAEFLRTRNFDYIRAAQAL 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005  242 GMRNSAIMFRHILPNAMISTLTFMPFILTGAIGTLTSLDFLGFGLPPGAPSLGELVAQGKSNLQAPWLGISAFVVLAVML 321
Cdd:PRK15021 242 GVSDRSIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGITAFLSVAILL 321

                        330
                 ....*....|....*...
gi 15597005  322 SLLVFIGEAARDAFDPRK 339
Cdd:PRK15021 322 SLLIFIGEAVRDAFDPNK 339
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 158-338 4.60e-20

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 86.20  E-value: 4.60e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005   158 GVTVGALQG-YYGGWVDLLGQRFLEVWSGLPVLYLLIILASFVQP----NFWWLLGIMLLFSWMSLVDVVRAEFLRGRNL 232
Cdd:pfam00528   1 GIPLGIIAAlRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILsilgHGILPAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005   233 EYVRAARALGMRNSAIMFRHILPNAMISTLTFMPFILTGAIGTLTSLDFLGfglppGAPSLGELVAQGKSNLQAPWlGIS 312
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLG-----SWPGLGLLLIEAILGYDYPE-IQG 154

                         170       180
                  ....*....|....*....|....*.
gi 15597005   313 AFVVLAVMLSLLVFIGEAARDAFDPR 338
Cdd:pfam00528 155 PVLAAALILLLLNLLVDILQRLLDPR 180
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 140-321 3.70e-19

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 83.87  E-value: 3.70e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005 140 FRVSILFALTLTVLSSLIGVTVGALQGYYGGWVDLLGQRFLEVWSGLPVLYLLIILASFVQPNFWWLL--------GIML 211
Cdd:cd06261   1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGIlpglglpaLILA 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005 212 LFSWMSLVDVVRAEFLRGRNLEYVRAARALGMRNSAIMFRHILPNAMISTLTFMPFILTGAIGTLTSLDFLGFGLPPGAP 291
Cdd:cd06261  81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                       170       180       190
                ....*....|....*....|....*....|
gi 15597005 292 SLGELVAQGKSNLQAPWLGISAFVVLAVML 321
Cdd:cd06261 161 TGLLLIFAILFPGDLGVAAAVALILLLLSL 190
 
Name Accession Description Interval E-value
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
 1-339 0e+00

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 671.48  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005   1 MRLSPINQRRWARFKSNKRGWWSLWLFLILFVGSLGAELIANDKPLVVHYDGGWYFPVFKRYPETTFGGEFPLEANYKSP 80
Cdd:COG4239   2 MRLSPLNRRRWRRFKANRRGYWSLWIFLVLFVLSLFAELIANDKPLLVSYDGELYFPVLKDYPETTFGGDFETEADYRDP 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005  81 YISQLIaEKDGWVLWPPIPYSYDTINYELKVPAPAPPSAENWLGTDDQARDVLARVIYGFRVSILFALTLTVLSSLIGVT 160
Cdd:COG4239  82 FVQELI-EAKGWALWPPIPYSYDTINYDLPSPAPSPPSAENWLGTDDQGRDVLARLIYGFRISVLFGLALTVISSVIGVA 160

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005 161 VGALQGYYGGWVDLLGQRFLEVWSGLPVLYLLIILASFVQPNFWWLLGIMLLFSWMSLVDVVRAEFLRGRNLEYVRAARA 240
Cdd:COG4239 161 AGAVQGYFGGRVDLLFQRFIEIWSSMPELYLLIILSSIFQPSFWLLLGILLLFGWMGLVGVVRAEFLRARNLEYVRAARA 240

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005 241 LGMRNSAIMFRHILPNAMISTLTFMPFILTGAIGTLTSLDFLGFGLPPGAPSLGELVAQGKSNLQAPWLGISAFVVLAVM 320
Cdd:COG4239 241 LGVSDRRIMFRHILPNAMVATLTFLPFILSGAITTLTSLDFLGFGLPPGSPSLGELLAQGKNNLQAPWLGLSAFVVLALM 320

                       330
                ....*....|....*....
gi 15597005 321 LSLLVFIGEAARDAFDPRK 339
Cdd:COG4239 321 LSLLVFIGEAVRDAFDPRK 339
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 2-339 5.96e-177

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 493.73  E-value: 5.96e-177
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005    2 RLSPINQRRWARFKSNKRGWWSLWLFLILFVGSLGAELIANDKPLVVHYDGGWYFPVFKRYPETTFGGEFPLEANYKSPY 81
Cdd:PRK15021   3 RLSPVNQARWARFRHNRRGYWSLWIFLVLFGLSLCSELIANDKPLLVRYDGSWYFPLLKNYSESDFGGPLASQADYQDPW 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005   82 ISQLIaEKDGWVLWPPIPYSYDTINYELKVPAPAPPSAENWLGTDDQARDVLARVIYGFRVSILFALTLTVLSSLIGVTV 161
Cdd:PRK15021  83 LKQRL-ENNGWVLWAPIRFGATSINFATDKPFPSPPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVLA 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005  162 GALQGYYGGWVDLLGQRFLEVWSGLPVLYLLIILASFVQPNFWWLLGIMLLFSWMSLVDVVRAEFLRGRNLEYVRAARAL 241
Cdd:PRK15021 162 GALQGYYGGKVDLWGQRFIEVWSGMPTLFLIILLSSVVQPNFWWLLAITVLFGWMSLVGVVRAEFLRTRNFDYIRAAQAL 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005  242 GMRNSAIMFRHILPNAMISTLTFMPFILTGAIGTLTSLDFLGFGLPPGAPSLGELVAQGKSNLQAPWLGISAFVVLAVML 321
Cdd:PRK15021 242 GVSDRSIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGITAFLSVAILL 321

                        330
                 ....*....|....*...
gi 15597005  322 SLLVFIGEAARDAFDPRK 339
Cdd:PRK15021 322 SLLIFIGEAVRDAFDPNK 339
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 99-336 9.02e-71

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 221.53  E-value: 9.02e-71
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005  99 PYSYDTINYElkvPAPAPPSAENWLGTDDQARDVLARVIYGFRVSILFALTLTVLSSLIGVTVGALQGYYGGWVDLLGQR 178
Cdd:COG1173  40 PYDPTAQDLA---ARLQPPSAAHWLGTDQLGRDVLSRLLYGARISLLVGLLAVLIALVIGVLLGLLAGYFGGWVDAVLMR 116

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005 179 FLEVWSGLPVLYLLIILASFVQPNFWWLLGIMLLFSWMSLVDVVRAEFLRGRNLEYVRAARALGMRNSAIMFRHILPNAM 258
Cdd:COG1173 117 LVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWPGYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVL 196

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15597005 259 ISTLTFMPFILTGAIGTLTSLDFLGFGLPPGAPSLGELVAQGKSNLQ-APWLGISAFVVLAVMLSLLVFIGEAARDAFD 336
Cdd:COG1173 197 PPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTMLSEGRNYLLtAPWLALFPGLAIVLTVLAFNLLGDGLRDALD 275
PRK15406 PRK15406
oligopeptide ABC transporter permease OppC; Provisional
 99-338 1.81e-31

oligopeptide ABC transporter permease OppC; Provisional


Pssm-ID: 185304 [Multi-domain]  Cd Length: 302  Bit Score: 119.94  E-value: 1.81e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005   99 PYSYDTINYELKVPAPAPPSAeNWLGTDDQARDVLARVIYGFRVSILFALTLTVLSSLIGVTVGALQGYYGGWVDLLGQR 178
Cdd:PRK15406  61 QFAYDDTDWGMMSSAPDMESG-HYFGTDSSGRDLLVRVAIGGRISLMVGVAAALVAVVVGTLYGSLSGYLGGKVDSVMMR 139

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005  179 FLEVWSGLPVLYLLIILASFVQPNFWWLLGIMLLFSWMSLVDVVRAEFLRGRNLEYVRAARALGMRNSAIMFRHILPNAM 258
Cdd:PRK15406 140 LLEILNSFPFMFFVILLVTFFGQNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTRGIVLRHIVPNVL 219

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005  259 ISTLTFMPFILTGAIGTLTSLDFLGFGLPPGAPSLGELVAQGKSNLQ-APWLGISAFVVLAVMLSLLVFIGEAARDAFDP 337
Cdd:PRK15406 220 GVVVVYASLLVPSMILFESFLSFLGLGTQEPLSSWGALLSDGANSMEvSPWLLLFPAGFLVVTLFCFNFIGDGLRDALDP 299


                 .
gi 15597005  338 R 338
Cdd:PRK15406 300 K 300
PRK15082 PRK15082
glutathione ABC transporter permease GsiD; Provisional
 100-338 2.07e-28

glutathione ABC transporter permease GsiD; Provisional


Pssm-ID: 185040 [Multi-domain]  Cd Length: 301  Bit Score: 111.74  E-value: 2.07e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005  100 YSYDTINyelkvpapAPPSAENWLGTDDQARDVLARVIYGFRVSILFALTLTVLSSLIGVTVGALQGYYGGWVDLLGQRF 179
Cdd:PRK15082  67 FDYDALN--------AGPSLQHWFGVDSLGRDIFSRILVGARISLAAGFFSVAIGAAIGTVLGLLAGYYEGWWDRIIMRI 138

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005  180 LEVWSGLPVLYLLIILASFVQPNFWWLLGIMLLFSWMSLVDVVRAEFLRGRNLEYVRAARALGMRNSAIMFRHILPNAMI 259
Cdd:PRK15082 139 CDVLFAFPGILLAIAVVAILGSGMANVIIAVAIFSIPAFARLVRGNTLVLKQQTYIESARSIGASDWTILLRHILPGTVS 218

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005  260 STLTFMPFILTGAIGTLTSLDFLGFGLPPGAPSLGELVAQGKSNL-QAPWLGIsaFVVLAVMLSLLVF--IGEAARDAFD 336
Cdd:PRK15082 219 SIVVYFTMRIGTSIITAASLSFLGLGAQPPTPEWGAMLNEARADMvIAPHVAL--FPSLAIFLTVLAFnlLGDGLRDALD 296


                 ..
gi 15597005  337 PR 338
Cdd:PRK15082 297 PK 298
PRK09881 PRK09881
D,D-dipeptide ABC transporter permease;
115-338 6.24e-27

D,D-dipeptide ABC transporter permease;


Pssm-ID: 182131 [Multi-domain]  Cd Length: 296  Bit Score: 107.60  E-value: 6.24e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005  115 APPSAENWLGTDDQARDVLARVIYGFRVSILFALTLTVLSSLIGVTVGALQGYYGGWVDLLGQRFLEVWSGLPVLYLLII 194
Cdd:PRK09881  68 LPPSAAHWFGTDEVGRDLFSRVLVGSQQSILAGLVVVAIAGMIGSLLGCLSGVLGGRADAIIMRIMDIMLSIPSLVLTMA 147

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005  195 LASFVQPNFWWLLGIMLLFSWMSLVDVVRAEFLRGRNLEYVRAARALGMRNSAIMFRHILPNAMISTLTFMPFILTGAIG 274
Cdd:PRK09881 148 LAAALGPSLFNAMLAIAIVRIPFYVRLARGQALVVRQYTYVQAAKTFGASRWHLISWHILRNSLPPLIVQASLDIGSAIL 227

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15597005  275 TLTSLDFLGFGLPPGAPSLGELVAQGKSNLQAPWLgISAFVVLAVMLSLLVF--IGEAARDAFDPR 338
Cdd:PRK09881 228 MAATLGFIGLGAQQPSAEWGAMVANGRNYVLDQWW-YCAFPGAAILLTAVGFnlFGDGIRDLLDPK 292
PRK10913 PRK10913
dipeptide ABC transporter permease DppC;
123-338 9.53e-27

dipeptide ABC transporter permease DppC;


Pssm-ID: 182833 [Multi-domain]  Cd Length: 300  Bit Score: 107.18  E-value: 9.53e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005  123 LGTDDQARDVLARVIYGFRVSILFALTLTVLSSLIGVTVGALQGYYGGWVDLLGQRFLEVWSGLPVLYLLIILASFVQPN 202
Cdd:PRK10913  81 LGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLVMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPS 160

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005  203 fwwLLGIMLLFSWMSL---VDVVRAEFLRGRNLEYVRAARALGMRNSAIMFRHILPNAMISTLTFMPFILTGAIGTLTSL 279
Cdd:PRK10913 161 ---IVNAALALTFVALphyVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINILPNCLAPLIVQASLGFSNAILDMAAL 237

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15597005  280 DFLGFGLPPGAPSLGELVAQGKSNLQAPWLgISAFVVLAVMLSLLVF--IGEAARDAFDPR 338
Cdd:PRK10913 238 GFLGMGAQPPTPEWGTMLSDVLQFAQSAWW-VVTFPGLAILLTVLAFnlMGDGLRDALDPK 297
SapC COG4171
ABC-type antimicrobial peptide export system, permease component SapC [Defense mechanisms];
99-338 1.11e-20

ABC-type antimicrobial peptide export system, permease component SapC [Defense mechanisms];


Pssm-ID: 443331 [Multi-domain]  Cd Length: 296  Bit Score: 90.26  E-value: 1.11e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005  99 PYSYDT--INYELKvpapaPPSAEN------WLGTDDQARDVLARVIYGFRVSILFALTLTVLSSLIGVTVGALQGYYGG 170
Cdd:COG4171  51 PYSPDQqfIGALLL-----PPSWDDngdvsfFLGTDDLGRDILSRLLYGARYTFGSALLVVLAAAIIGGIIGILAGMSRG 125

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005 171 WVDLLGQRFLEVWSGLPVLYLLIILASFVQPNFW-WLLGImllfsWMSLV--------DVVRAEFLRgrnlEYVRAARAL 241
Cdd:COG4171 126 LKSSILNHLLDTLLSIPSLLLAIIIVALLGPGLEnAMLAI-----TLALLpqfihaiyQAVHQELKK----EYVLAARLD 196

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005 242 GMRNSAIMFRHILPNAMISTLTFMPFILTGAIGTLTSLDFLGFGLPPGAPSLGELVAQGKSNLQ-APWLgisafVVL--- 317
Cdd:COG4171 197 GASNWQLLRYSILPNILEVLVTELTRALSIAILDISALGFLGLGAQLPSPEWGAMLGDSLELIYlAPWT-----VILpgl 271

                       250       260
                ....*....|....*....|...
gi 15597005 318 AVMLSLLV--FIGEAARDAFDPR 338
Cdd:COG4171 272 AIMFSVLIvnLVGDGLRRALNKG 294
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 158-338 4.60e-20

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 86.20  E-value: 4.60e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005   158 GVTVGALQG-YYGGWVDLLGQRFLEVWSGLPVLYLLIILASFVQP----NFWWLLGIMLLFSWMSLVDVVRAEFLRGRNL 232
Cdd:pfam00528   1 GIPLGIIAAlRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILsilgHGILPAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005   233 EYVRAARALGMRNSAIMFRHILPNAMISTLTFMPFILTGAIGTLTSLDFLGfglppGAPSLGELVAQGKSNLQAPWlGIS 312
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLG-----SWPGLGLLLIEAILGYDYPE-IQG 154

                         170       180
                  ....*....|....*....|....*.
gi 15597005   313 AFVVLAVMLSLLVFIGEAARDAFDPR 338
Cdd:pfam00528 155 PVLAAALILLLLNLLVDILQRLLDPR 180
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 140-321 3.70e-19

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 83.87  E-value: 3.70e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005 140 FRVSILFALTLTVLSSLIGVTVGALQGYYGGWVDLLGQRFLEVWSGLPVLYLLIILASFVQPNFWWLL--------GIML 211
Cdd:cd06261   1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGIlpglglpaLILA 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005 212 LFSWMSLVDVVRAEFLRGRNLEYVRAARALGMRNSAIMFRHILPNAMISTLTFMPFILTGAIGTLTSLDFLGFGLPPGAP 291
Cdd:cd06261  81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                       170       180       190
                ....*....|....*....|....*....|
gi 15597005 292 SLGELVAQGKSNLQAPWLGISAFVVLAVML 321
Cdd:cd06261 161 TGLLLIFAILFPGDLGVAAAVALILLLLSL 190
nikC PRK10417
nickel transporter permease NikC; Provisional
 116-337 3.89e-19

nickel transporter permease NikC; Provisional


Pssm-ID: 236687 [Multi-domain]  Cd Length: 272  Bit Score: 85.49  E-value: 3.89e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005  116 PPSAENWLGTDDQARDVLARVIYGFRVSILFALTLTVLSSLIGVTVGALQGYYGGWVDLLGQRFLEVWSGLPVLYLLIIL 195
Cdd:PRK10417  42 SPDAQHWLGTDHLGRDIFSRLMAGTRVSLGSVMACLLLVLALGLVIGGSAGLLGGRVDQATMRVADMFMTFPTSILAFFM 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005  196 ASFVQPNFWWLLGIMLLFSWMSLVDVVRAEFLRGRNLEYVRAARALGMRNSAIMFRHILPNAMISTLTFMPFILTGAIGT 275
Cdd:PRK10417 122 VGVLGTGLTNVIIAIALSHWAWYARMVRSLVISLRQREFVLAARLSGAGHVRVFIDHLLPAVIPQLLVLATLDIGHMMLH 201

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15597005  276 LTSLDFLGFGLPPGAPSLGELVAQGKS-----NLQAPWLGisafvvLAVMLSLLVF--IGEAARDAFDP 337
Cdd:PRK10417 202 VAGLSFLGLGVTAPTAEWGVMINDARQyiwtqPLLMFWPG------LALFISVMAFnlLGDALRDHLDP 264
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 130-273 9.52e-12

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 64.70  E-value: 9.52e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005 130 RDVLARVIYGFRVSILFALTLTVLSSLIGVTVGALQGYY-GGWVDllgqrflevwsglpvlYLLIILASFVQ--PNFWWL 206
Cdd:COG0601  85 RPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRrGSWLD----------------RLITVLALLGIsiPSFWLG 148

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005 207 LGIMLLFS--------------WMSLVD----------------------VVRAEFLRGRNLEYVRAARALGMRNSAIMF 250
Cdd:COG0601 149 LLLILLFAvklgwlpvsgrvspWEDFLDalrhlilpaltlalgslagiarLTRSSMLEVLGQDYVRTARAKGLSERRVLL 228

                       170       180
                ....*....|....*....|....*..
gi 15597005 251 RHILPNAMISTLTFM----PFILTGAI 273
Cdd:COG0601 229 RHALRNALIPVVTVLglqlGGLLGGAV 255
PRK15111 PRK15111
peptide ABC transporter permease SapC;
122-336 2.20e-09

peptide ABC transporter permease SapC;


Pssm-ID: 185066 [Multi-domain]  Cd Length: 296  Bit Score: 57.79  E-value: 2.20e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005  122 WLGTDDQARDVLARVIYGFRVSILFALTLTVLSSLIGVTVGALQGYYGGWVDLLGQRFLEVWSGLPVLYLLIILASFVQP 201
Cdd:PRK15111  77 FLGTDDLGRDVLSRLLSGAAPTVGGAFVVTLAATLCGLVLGVFAGATHGLRSAVLNHILDTLLSIPSLLLAIIVVAFAGP 156

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005  202 NfwwlLGIMLLFSWMSLVD-VVRAEFLRGR---NLEYVRAARALGMRNSAIMFRHILPNAMISTLTFMPFILTGAIGTLT 277
Cdd:PRK15111 157 S----LSHAMFAVWLALLPrMVRSIYSAVHdelEKEYVIAARLDGASTLNILWYAVLPNITAGLVTEITRALSMAILDIA 232

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15597005  278 SLDFLGFGLPPGAPSLGELVAQGKSNLQ-APWLgisafVVL---AVMLSLLV--FIGEAARDAFD 336
Cdd:PRK15111 233 ALGFLDLGAQLPSPEWGAMLGDSLELIYvAPWT-----VMLpgaAIMLSVLLvnLLGDGIRRAII 292
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 131-258 8.05e-05

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 43.14  E-value: 8.05e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597005 131 DVLARVIYGFRVSILFALTLTVLSSLIGVTVGALQGYYGGWVDLLGQRFLEVWSGLPVLyLLIILASFVQPNFWWLLGIM 210
Cdd:COG0765  10 DYLPLLLEGLLVTLLLTVLAIVLGLVLGLLLALARLSPNPVLRWLATAYVEFFRGTPLL-VQLFFIYFGLPLLGIDLSPF 88

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 15597005 211 L-------LFSWMSLVDVVRAEFL---RGRnleyVRAARALGMRNSAIMFRHILPNAM 258
Cdd:COG0765  89 VaavialtLNSAAYLAEIVRAGIQsvpKGQ----WEAARALGLSRWQTMRRIILPQAL 142
PRK15081 PRK15081
glutathione ABC transporter permease GsiC; Provisional
 223-273 5.66e-04

glutathione ABC transporter permease GsiC; Provisional


Pssm-ID: 185039 [Multi-domain]  Cd Length: 306  Bit Score: 41.24  E-value: 5.66e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 15597005  223 RAEFLRGRNLEYVRAARALGMRNSAIMFRHILPNAMISTLTFM----PFILTGAI 273
Cdd:PRK15081 193 RASFVEVLSEDYMRTARAKGVSETWVVLKHGLRNAMIPVVTMMglqfGFLLGGSI 247
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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