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Conserved domains on  [gi|15596765|ref|NP_250259|]
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hypothetical protein PA1568 [Pseudomonas aeruginosa PAO1]

Protein Classification

RidA family protein( domain architecture ID 10150280)

RidA (reactive intermediate/imine deaminase A) family protein similar to 2-iminobutanoate/2-iminopropanoate deaminase, which catalyzes the deamination of enamine/imine intermediates to yield 2-ketobutyrate and ammonia

CATH:  3.30.1330.40
PubMed:  14624641

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YjgF_YER057c_UK114_like_2 cd06150
This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in ...
 10-114 1.82e-50

This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no functional connection. Members of this family have been implicated in isoleucine (Yeo7, Ibm1, aldR) and purine (YjgF) biosynthesis, as well as threonine anaerobic degradation (tdcF) and mitochondrial DNA maintenance (Ibm1). This domain homotrimerizes forming a distinct intersubunit cavity that may serve as a small molecule binding site.


:

Pssm-ID: 100007  Cd Length: 105  Bit Score: 155.00  E-value: 1.82e-50
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596765  10 KRRAEMALHGNTVYIGGQVADDPSGDIQDQTRQILENIDRLLQSVGSDRGQVLSVRILLAHREDYAGLNQVWDQWFPEGR 89
Cdd:cd06150   1 ARMSQAVVHNGTVYLAGQVADDTSADITGQTRQVLAKIDALLAEAGSDKSRILSATIWLADMADFAAMNAVWDAWVPPGH 80

                        90       100
                ....*....|....*....|....*
gi 15596765  90 APTRACSLAELIDPRWRVEMIVVAA 114
Cdd:cd06150  81 APARACVEAKLADPGYLVEIVVTAA 105
 
Name Accession Description Interval E-value
YjgF_YER057c_UK114_like_2 cd06150
This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in ...
 10-114 1.82e-50

This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no functional connection. Members of this family have been implicated in isoleucine (Yeo7, Ibm1, aldR) and purine (YjgF) biosynthesis, as well as threonine anaerobic degradation (tdcF) and mitochondrial DNA maintenance (Ibm1). This domain homotrimerizes forming a distinct intersubunit cavity that may serve as a small molecule binding site.


Pssm-ID: 100007  Cd Length: 105  Bit Score: 155.00  E-value: 1.82e-50
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596765  10 KRRAEMALHGNTVYIGGQVADDPSGDIQDQTRQILENIDRLLQSVGSDRGQVLSVRILLAHREDYAGLNQVWDQWFPEGR 89
Cdd:cd06150   1 ARMSQAVVHNGTVYLAGQVADDTSADITGQTRQVLAKIDALLAEAGSDKSRILSATIWLADMADFAAMNAVWDAWVPPGH 80

                        90       100
                ....*....|....*....|....*
gi 15596765  90 APTRACSLAELIDPRWRVEMIVVAA 114
Cdd:cd06150  81 APARACVEAKLADPGYLVEIVVTAA 105
RidA COG0251
Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 ...
 18-116 2.31e-30

Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family [Defense mechanisms]; Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family is part of the Pathway/BioSystem: Pyrimidine degradation


Pssm-ID: 440021  Cd Length: 125  Bit Score: 104.87  E-value: 2.31e-30
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596765  18 HGNTVYIGGQVADDP-----SGDIQDQTRQILENIDRLLQSVGSDRGQVLSVRILLAHREDYAGLNQVWDQWFPEGRaPT 92
Cdd:COG0251  23 VGNLVFVSGQVPLDPdtgelGGDIEAQTRQVLENILAVLAAAGGSLDDVVKVTVYLTDMADFAAVNEVYAEYFGEGR-PA 101

                        90       100
                ....*....|....*....|....*...
gi 15596765  93 RAC----SLAElidpRWRVEMIVVAARP 116
Cdd:COG0251 102 RTAvgvaALPK----GALVEIEAIAALP 125
Ribonuc_L-PSP pfam01042
Endoribonuclease L-PSP; Endoribonuclease active on single-stranded mRNA. Inhibits protein ...
 18-114 4.89e-28

Endoribonuclease L-PSP; Endoribonuclease active on single-stranded mRNA. Inhibits protein synthesis by cleavage of mRNA. Previously thought to inhibit protein synthesis initiation. This protein may also be involved in the regulation of purine biosynthesis. YjgF (renamed RidA) family members are enamine/imine deaminases. They hydrolyze reactive intermediates released by PLP-dependent enzymes, including threonine dehydratase. YjgF also prevents inhibition of transaminase B (IlvE) in Salmonella.


Pssm-ID: 426010  Cd Length: 117  Bit Score: 98.91  E-value: 4.89e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596765    18 HGNTVYIGGQVADDP------SGDIQDQTRQILENIDRLLQSVGSDRGQVLSVRILLAHREDYAGLNQVWDQWFPEGRAP 91
Cdd:pfam01042  15 AGNLVYVSGQIPLDPdtgklvEGDVAEQTRQVLENIKAVLAAAGASLSDVVKVTIFLADMNDFAEVNEVYAEYFDADKAP 94

                          90       100
                  ....*....|....*....|...
gi 15596765    92 TRACSLAELIDPRWRVEMIVVAA 114
Cdd:pfam01042  95 ARSAVGVAALPLGALVEIEAIAV 117
TIGR00004 TIGR00004
reactive intermediate/imine deaminase; This protein was described initially as an inhibitor of ...
 19-115 3.72e-19

reactive intermediate/imine deaminase; This protein was described initially as an inhibitor of protein synthesis intiation, then as an endoribonuclease active on single-stranded mRNA, endoribonuclease L-PSP. Members of this family, conserved in all domains of life and often with several members per bacterial genome, appear to catalyze a reaction that minimizes toxic by-products from reactions catalyzed by pyridoxal phosphate-dependent enzymes. [Cellular processes, Other]


Pssm-ID: 129116  Cd Length: 124  Bit Score: 76.18  E-value: 3.72e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596765    19 GNTVYIGGQVADDPS------GDIQDQTRQILENIDRLLQSVGSDRGQVLSVRILLAHREDYAGLNQVWDQWFPEGRaPT 92
Cdd:TIGR00004  23 GNTVYVSGQIPLDPStgelvgGDIAEQAEQVLENLKAILEAAGLSLDDVVKTTVFLTDLNDFAEVNEVYGQYFDEHY-PA 101

                          90       100
                  ....*....|....*....|....*
gi 15596765    93 RAC-SLAELidPR-WRVEMIVVAAR 115
Cdd:TIGR00004 102 RSAvQVAAL--PKgVLVEIEAIAVK 124
PRK11401 PRK11401
enamine/imine deaminase;
19-115 3.84e-11

enamine/imine deaminase;


Pssm-ID: 105214  Cd Length: 129  Bit Score: 55.84  E-value: 3.84e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596765   19 GNTVYIGGQVADDP-----SGDIQDQTRQILENIDRLLQSVGSDRGQVLSVRILLAHREDYAGLNQVWDQWFPEGRA--P 91
Cdd:PRK11401  24 GSMVFTSGQIPVCPqtgeiPADVQDQARLSLENVKAIVVAAGLSVGDIIKMTVFITDLNDFATINEVYKQFFDEHQAtyP 103

                         90       100
                 ....*....|....*....|....
gi 15596765   92 TRACSLAELIDPRWRVEMIVVAAR 115
Cdd:PRK11401 104 TRSCVQVARLPKDVKLEIEAIAVR 127
 
Name Accession Description Interval E-value
YjgF_YER057c_UK114_like_2 cd06150
This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in ...
 10-114 1.82e-50

This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no functional connection. Members of this family have been implicated in isoleucine (Yeo7, Ibm1, aldR) and purine (YjgF) biosynthesis, as well as threonine anaerobic degradation (tdcF) and mitochondrial DNA maintenance (Ibm1). This domain homotrimerizes forming a distinct intersubunit cavity that may serve as a small molecule binding site.


Pssm-ID: 100007  Cd Length: 105  Bit Score: 155.00  E-value: 1.82e-50
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596765  10 KRRAEMALHGNTVYIGGQVADDPSGDIQDQTRQILENIDRLLQSVGSDRGQVLSVRILLAHREDYAGLNQVWDQWFPEGR 89
Cdd:cd06150   1 ARMSQAVVHNGTVYLAGQVADDTSADITGQTRQVLAKIDALLAEAGSDKSRILSATIWLADMADFAAMNAVWDAWVPPGH 80

                        90       100
                ....*....|....*....|....*
gi 15596765  90 APTRACSLAELIDPRWRVEMIVVAA 114
Cdd:cd06150  81 APARACVEAKLADPGYLVEIVVTAA 105
YjgF_YER057c_UK114_family cd00448
YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, ...
 18-113 2.93e-32

YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no functional connection. Members of this family have been implicated in isoleucine (Yeo7, Ibm1, aldR) and purine (YjgF) biosynthesis, as well as threonine anaerobic degradation (tdcF) and mitochondrial DNA maintenance (Ibm1). This domain homotrimerizes forming a distinct intersubunit cavity that may serve as a small molecule binding site.


Pssm-ID: 100004 [Multi-domain]  Cd Length: 107  Bit Score: 109.19  E-value: 2.93e-32
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596765  18 HGNTVYIGGQVADDP-----SGDIQDQTRQILENIDRLLQSVGSDRGQVLSVRILLAHREDYAGLNQVWDQWFPEGRAPT 92
Cdd:cd00448   7 VGNLVFVSGQIPLDPdgelvPGDIEAQTRQALENLEAVLEAAGGSLDDVVKVTVYLTDMADFAAVNEVYDEFFGEGPPPA 86

                        90       100
                ....*....|....*....|.
gi 15596765  93 RACSLAELIDPRWRVEMIVVA 113
Cdd:cd00448  87 RTAVGVAALPPGALVEIEAIA 107
RidA COG0251
Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 ...
 18-116 2.31e-30

Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family [Defense mechanisms]; Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family is part of the Pathway/BioSystem: Pyrimidine degradation


Pssm-ID: 440021  Cd Length: 125  Bit Score: 104.87  E-value: 2.31e-30
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596765  18 HGNTVYIGGQVADDP-----SGDIQDQTRQILENIDRLLQSVGSDRGQVLSVRILLAHREDYAGLNQVWDQWFPEGRaPT 92
Cdd:COG0251  23 VGNLVFVSGQVPLDPdtgelGGDIEAQTRQVLENILAVLAAAGGSLDDVVKVTVYLTDMADFAAVNEVYAEYFGEGR-PA 101

                        90       100
                ....*....|....*....|....*...
gi 15596765  93 RAC----SLAElidpRWRVEMIVVAARP 116
Cdd:COG0251 102 RTAvgvaALPK----GALVEIEAIAALP 125
Ribonuc_L-PSP pfam01042
Endoribonuclease L-PSP; Endoribonuclease active on single-stranded mRNA. Inhibits protein ...
 18-114 4.89e-28

Endoribonuclease L-PSP; Endoribonuclease active on single-stranded mRNA. Inhibits protein synthesis by cleavage of mRNA. Previously thought to inhibit protein synthesis initiation. This protein may also be involved in the regulation of purine biosynthesis. YjgF (renamed RidA) family members are enamine/imine deaminases. They hydrolyze reactive intermediates released by PLP-dependent enzymes, including threonine dehydratase. YjgF also prevents inhibition of transaminase B (IlvE) in Salmonella.


Pssm-ID: 426010  Cd Length: 117  Bit Score: 98.91  E-value: 4.89e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596765    18 HGNTVYIGGQVADDP------SGDIQDQTRQILENIDRLLQSVGSDRGQVLSVRILLAHREDYAGLNQVWDQWFPEGRAP 91
Cdd:pfam01042  15 AGNLVYVSGQIPLDPdtgklvEGDVAEQTRQVLENIKAVLAAAGASLSDVVKVTIFLADMNDFAEVNEVYAEYFDADKAP 94

                          90       100
                  ....*....|....*....|...
gi 15596765    92 TRACSLAELIDPRWRVEMIVVAA 114
Cdd:pfam01042  95 ARSAVGVAALPLGALVEIEAIAV 117
TIGR00004 TIGR00004
reactive intermediate/imine deaminase; This protein was described initially as an inhibitor of ...
 19-115 3.72e-19

reactive intermediate/imine deaminase; This protein was described initially as an inhibitor of protein synthesis intiation, then as an endoribonuclease active on single-stranded mRNA, endoribonuclease L-PSP. Members of this family, conserved in all domains of life and often with several members per bacterial genome, appear to catalyze a reaction that minimizes toxic by-products from reactions catalyzed by pyridoxal phosphate-dependent enzymes. [Cellular processes, Other]


Pssm-ID: 129116  Cd Length: 124  Bit Score: 76.18  E-value: 3.72e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596765    19 GNTVYIGGQVADDPS------GDIQDQTRQILENIDRLLQSVGSDRGQVLSVRILLAHREDYAGLNQVWDQWFPEGRaPT 92
Cdd:TIGR00004  23 GNTVYVSGQIPLDPStgelvgGDIAEQAEQVLENLKAILEAAGLSLDDVVKTTVFLTDLNDFAEVNEVYGQYFDEHY-PA 101

                          90       100
                  ....*....|....*....|....*
gi 15596765    93 RAC-SLAELidPR-WRVEMIVVAAR 115
Cdd:TIGR00004 102 RSAvQVAAL--PKgVLVEIEAIAVK 124
YjgF_YER057c_UK114_like_6 cd06154
This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in ...
 18-113 5.68e-14

This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no functional connection. Members of this family have been implicated in isoleucine (Yeo7, Ibm1, aldR) and purine (YjgF) biosynthesis, as well as threonine anaerobic degradation (tdcF) and mitochondrial DNA maintenance (Ibm1). This domain homotrimerizes forming a distinct intersubunit cavity that may serve as a small molecule binding site.


Pssm-ID: 100011  Cd Length: 119  Bit Score: 62.96  E-value: 5.68e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596765  18 HGNTVYIGGQVADDP-----SGDIQDQTRQILENIDRLLQSVGSDRGQVLSVRILLAHREDYAGLNQVWDQWFPEGR--A 90
Cdd:cd06154  19 VGNWVFVSGTTGYDYdgmvmPGDAYEQTRQCLEIIEAALAEAGASLEDVVRTRMYVTDIADFEAVGRAHGEVFGDIRpaA 98

                        90       100
                ....*....|....*....|...
gi 15596765  91 PTRACSLaeLIDPRWRVEMIVVA 113
Cdd:cd06154  99 TMVVVSL--LVDPEMLVEIEVTA 119
YjgF_YER057c_UK114_like_3 cd06151
This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in ...
 21-113 1.40e-11

This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no functional connection. Members of this family have been implicated in isoleucine (Yeo7, Ibm1, aldR) and purine (YjgF) biosynthesis, as well as threonine anaerobic degradation (tdcF) and mitochondrial DNA maintenance (Ibm1). This domain homotrimerizes forming a distinct intersubunit cavity that may serve as a small molecule binding site.


Pssm-ID: 100008  Cd Length: 126  Bit Score: 56.94  E-value: 1.40e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596765  21 TVYIGGQVAD--DPS---------GDIQDQTRQILENIDRLLQSVGSDRGQVLSVRILLA------HREDYAGLNQVWDQ 83
Cdd:cd06151  13 TIYLSGTVPAvvNASapkgsparyGDTETQTISVLKRIETILQSQGLTMGDVVKMRVFLVadpaldGKMDFAGFMKAYRQ 92

                        90       100       110
                ....*....|....*....|....*....|....
gi 15596765  84 WF--PEGRA-PTR-ACSLAELIDPRWRVEMIVVA 113
Cdd:cd06151  93 FFgtAEQPNkPARsTLQVAGLVNPGWLVEIEVVA 126
PRK11401 PRK11401
enamine/imine deaminase;
19-115 3.84e-11

enamine/imine deaminase;


Pssm-ID: 105214  Cd Length: 129  Bit Score: 55.84  E-value: 3.84e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596765   19 GNTVYIGGQVADDP-----SGDIQDQTRQILENIDRLLQSVGSDRGQVLSVRILLAHREDYAGLNQVWDQWFPEGRA--P 91
Cdd:PRK11401  24 GSMVFTSGQIPVCPqtgeiPADVQDQARLSLENVKAIVVAAGLSVGDIIKMTVFITDLNDFATINEVYKQFFDEHQAtyP 103

                         90       100
                 ....*....|....*....|....
gi 15596765   92 TRACSLAELIDPRWRVEMIVVAAR 115
Cdd:PRK11401 104 TRSCVQVARLPKDVKLEIEAIAVR 127
eu_AANH_C_1 cd06155
A group of hypothetical eukaryotic proteins, characterized by the presence of an adenine ...
 19-95 4.57e-11

A group of hypothetical eukaryotic proteins, characterized by the presence of an adenine nucleotide alpha hydrolase (AANH)-like domain located N-terminal to two distinctly different YjgF-YER057c-UK114-like domains. This CD contains the first of these domains. The YjgF-YER057c-UK114 protein family is a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no functional connection. Members of this family have been implicated in isoleucine (Yeo7, Ibm1, aldR) and purine (YjgF) biosynthesis, as well as threonine anaerobic degradation (tdcF) and mitochondrial DNA maintenance (Ibm1). This domain homotrimerizes forming a distinct intersubunit cavity that may serve as a small molecule binding site.


Pssm-ID: 100012  Cd Length: 101  Bit Score: 54.96  E-value: 4.57e-11
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15596765  19 GNTVYIGGQVADDPSGDIQDQTRQILENIDRLLQSVGSDRGQVLSVRILLAHREDYAGLNQVWDQWFPEGRAPTRAC 95
Cdd:cd06155   7 GGLLWISNVTASESDETVEEQMESIFSKLREILQSNGLSLSDILYVTLYLRDMSDFAEVNSVYGTFFDKPNPPSRVC 83
YjgH_like cd02198
YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, ...
 13-115 1.47e-08

YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no functional connection. Members of this family have been implicated in isoleucine (Yeo7, Ibm1, aldR) and purine (YjgF) biosynthesis, as well as threonine anaerobic degradation (tdcF) and mitochondrial DNA maintenance (Ibm1). This domain homotrimerizes forming a distinct intersubunit cavity that may serve as a small molecule binding site.


Pssm-ID: 100005  Cd Length: 111  Bit Score: 48.80  E-value: 1.47e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596765  13 AEMALHGNTVYIGGQVADDPSG----DIQDQTRQILENIDRLLQSVGSDRGQVlsVRILLAH---REDYAGLNQVWDQWF 85
Cdd:cd02198   4 SPAVRVGDTLFVSGQVGSDADGsvaeDFEAQFRLAFQNLGAVLEAAGCSFDDV--VELTTFHvdmAAHLPAFAAVKDEYF 81

                        90       100       110
                ....*....|....*....|....*....|
gi 15596765  86 PEGRAPTRACSLAELIDPRWRVEMIVVAAR 115
Cdd:cd02198  82 KEPYPAWTAVGVAWLARPGLLVEIKVVAVR 111
YjgF_YER057c_UK114_like_5 cd06153
This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in ...
 34-109 6.41e-03

This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no functional connection. Members of this family have been implicated in isoleucine (Yeo7, Ibm1, aldR) and purine (YjgF) biosynthesis, as well as threonine anaerobic degradation (tdcF) and mitochondrial DNA maintenance (Ibm1). This domain homotrimerizes forming a distinct intersubunit cavity that may serve as a small molecule binding site.


Pssm-ID: 100010  Cd Length: 114  Bit Score: 33.77  E-value: 6.41e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596765  34 GDIQDQTRQILENIDRLLQSVGSDRGQ-----VLSVRILLAHREDYAGLNQVWDQWFPEgrAPTRACSLAELIDPRWRVE 108
Cdd:cd06153  32 GDVEAQTRETLENIEALLEAAGRGGGAqfladLLRLKVYLRDREDLPAVRAILAARLGP--AVPAVFLQADVCRPDLLVE 109


                .
gi 15596765 109 M 109
Cdd:cd06153 110 I 110
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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