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Conserved domains on  [gi|15596225|ref|NP_249719|]
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oxidoreductase [Pseudomonas aeruginosa PAO1]

Protein Classification

NAD(P)/FAD-dependent oxidoreductase( domain architecture ID 11429741)

FAD/NAD(P)-binding oxidoreductase that catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant

CATH:  3.30.9.10
EC:  1.-.-.-
Gene Ontology:  GO:0016491|GO:0050660
SCOP:  3000055

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
27-396 4.67e-78

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


:

Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 246.36  E-value: 4.67e-78
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225  27 QRADVCVIGAGFTGLSAALHLLEAGRSVCVLEAYEVGHGGSGRNVGLINAGtwippdevvatLGAEQGEKLNAVLGRAPA 106
Cdd:COG0665   1 ATADVVVIGGGIAGLSTAYHLARRGLDVTVLERGRPGSGASGRNAGQLRPG-----------LAALADRALVRLAREALD 69

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225 107 LVMETIERLGIDCQLRREGTLHMSHNASGVADLQRRHAQWTRRGAPLELLTGAACHE---ACGTRRISAALLDRRAGTLN 183
Cdd:COG0665  70 LWRELAAELGIDCDFRRTGVLYLARTEAELAALRAEAEALRALGLPVELLDAAELRErepGLGSPDYAGGLYDPDDGHVD 149

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225 184 PMAYSRGLATAVVQRGGQLYQRSPVLALERQGALW-AVRSSAGAVLAEQVVIASNAYTEGEWTNLRRH--FFPGYYYQVA 260
Cdd:COG0665 150 PAKLVRALARAARAAGVRIREGTPVTGLEREGGRVtGVRTERGTVRADAVVLAAGAWSARLLPMLGLRlpLRPVRGYVLV 229

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225 261 SAPLHGaaaeriLPHGQGSWDTRTvlsSIRRDAQGRLLLGS---LGNGANKPAWFLRQWADRIQSHYFPDLGQVNWEYSW 337
Cdd:COG0665 230 TEPLPD------LPLRPVLDDTGV---YLRPTADGRLLVGGtaePAGFDRAPTPERLEALLRRLRRLFPALADAEIVRAW 300

                       330       340       350       360       370       380
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15596225 338 TGCIAFTPDHLMRLFE--PAEGLLAVTGYNGRGVTTGTVVGKAFADYLLSGERATLPLPFS 396
Cdd:COG0665 301 AGLRPMTPDGLPIIGRlpGAPGLYVATGHGGHGVTLAPAAGRLLADLILGGEPPLDLAPFS 361
 
Name Accession Description Interval E-value
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
27-396 4.67e-78

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 246.36  E-value: 4.67e-78
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225  27 QRADVCVIGAGFTGLSAALHLLEAGRSVCVLEAYEVGHGGSGRNVGLINAGtwippdevvatLGAEQGEKLNAVLGRAPA 106
Cdd:COG0665   1 ATADVVVIGGGIAGLSTAYHLARRGLDVTVLERGRPGSGASGRNAGQLRPG-----------LAALADRALVRLAREALD 69

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225 107 LVMETIERLGIDCQLRREGTLHMSHNASGVADLQRRHAQWTRRGAPLELLTGAACHE---ACGTRRISAALLDRRAGTLN 183
Cdd:COG0665  70 LWRELAAELGIDCDFRRTGVLYLARTEAELAALRAEAEALRALGLPVELLDAAELRErepGLGSPDYAGGLYDPDDGHVD 149

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225 184 PMAYSRGLATAVVQRGGQLYQRSPVLALERQGALW-AVRSSAGAVLAEQVVIASNAYTEGEWTNLRRH--FFPGYYYQVA 260
Cdd:COG0665 150 PAKLVRALARAARAAGVRIREGTPVTGLEREGGRVtGVRTERGTVRADAVVLAAGAWSARLLPMLGLRlpLRPVRGYVLV 229

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225 261 SAPLHGaaaeriLPHGQGSWDTRTvlsSIRRDAQGRLLLGS---LGNGANKPAWFLRQWADRIQSHYFPDLGQVNWEYSW 337
Cdd:COG0665 230 TEPLPD------LPLRPVLDDTGV---YLRPTADGRLLVGGtaePAGFDRAPTPERLEALLRRLRRLFPALADAEIVRAW 300

                       330       340       350       360       370       380
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15596225 338 TGCIAFTPDHLMRLFE--PAEGLLAVTGYNGRGVTTGTVVGKAFADYLLSGERATLPLPFS 396
Cdd:COG0665 301 AGLRPMTPDGLPIIGRlpGAPGLYVATGHGGHGVTLAPAAGRLLADLILGGEPPLDLAPFS 361
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 30-381 4.08e-56

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 188.38  E-value: 4.08e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225    30 DVCVIGAGFTGLSAALHLLEAGRSVCVLEAY-EVGHGGSGRNVGLINAGTWIPPDEVVATLGAEqgeklnavlgrAPALV 108
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGLSVTLLERGdDPGSGASGRNAGLIHPGLRYLEPSELARLALE-----------ALDLW 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225   109 METIERLGIDCQLRREGTLHMSHNASGvADLQRRHAQWTRRGAPLELLTGAACHEAC-GTRRISAALLDRRAGTLNPMAY 187
Cdd:pfam01266  70 EELEEELGIDCGFRRCGVLVLARDEEE-EALEKLLAALRRLGVPAELLDAEELRELEpLLPGLRGGLFYPDGGHVDPARL 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225   188 SRGLATAVVQRGGQLYQRSPVLALERQGALWAVRSSAgavLAEQVVIASNAYT-EGEWTNLRRHFFPGYYYQVASAPLHG 266
Cdd:pfam01266 149 LRALARAAEALGVRIIEGTEVTGIEEEGGVWGVVTTG---EADAVVNAAGAWAdLLALPGLRLPVRPVRGQVLVLEPLPE 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225   267 AAAERILPHgqgsWDTRTVLSSIRRDAQGRLLLGS----LGNGANKPAWFLRQWADRIQSHYFPDLGQVnwEYSWTGCIA 342
Cdd:pfam01266 226 ALLILPVPI----TVDPGRGVYLRPRADGRLLLGGtdeeDGFDDPTPDPEEIEELLEAARRLFPALADI--ERAWAGLRP 299

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 15596225   343 fTPDHLMRLFEP-AEGLLAVTGYNGRGVTTGTVVGKAFAD 381
Cdd:pfam01266 300 -LPDGLPIIGRPgSPGLYLATGHGGHGLTLAPGIGKLLAE 338
thiamin_ThiO TIGR02352
glycine oxidase ThiO; This family consists of the homotetrameric, FAD-dependent glycine ...
 47-387 1.09e-10

glycine oxidase ThiO; This family consists of the homotetrameric, FAD-dependent glycine oxidase ThiO, from species such as Bacillus subtilis that use glycine in thiamine biosynthesis. In general, members of this family will not be found in species such as E. coli that instead use tyrosine and the ThiH protein. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine]


Pssm-ID: 274092 [Multi-domain]  Cd Length: 337  Bit Score: 62.77  E-value: 1.09e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225    47 LLEAGRSVCVLEAYEVGHGGSGRNVGLINAGT-WIPPDEVVATLGAEQgeklnavLGRAPALVMETIERLGIDCQLRREG 125
Cdd:TIGR02352   3 LAKRGHSVTLFDRDPMGGGASWAAAGMLAPHAeCEYAEDPLFDLALES-------LRLYPEWLEALKELTGLDTGYHQCG 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225   126 TLHMSHNASGVADLQRRHAQWTRRGAPLELLTGAACH--EACGTRRISAALLDRRAGTLNPMAYSRGLATAVVQRGGQLY 203
Cdd:TIGR02352  76 TLVVAFDEDDVEHLRQLADLQSATGMEVEWLSGRALRrlEPYLSGGIRGAVFYPDDAHVDPRALLKALEKALEKLGVEII 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225   204 QRSPVLALERQGAL-WAVRSSAGAVLAEQVVIASnayteGEWTnlrRHFFPGYYYQVASAPLHGAAAERILPhgqgswdT 282
Cdd:TIGR02352 156 EHTEVQHIEIRGEKvTAIVTPSGDVQADQVVLAA-----GAWA---GELLPLPLRPVRGQPLRLEAPAVPLL-------N 220

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225   283 RTVLSSIRRD-------AQGRLLLGSlgngANKPAWF-----------LRQWADRIqshyFPDLGQVNWEYSWTGCIAFT 344
Cdd:TIGR02352 221 RPLRAVVYGRrvyivprRDGRLVVGA----TMEESGFdttptlggikeLLRDAYTI----LPALKEARLLETWAGLRPGT 292

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 15596225   345 PDHLMRLFEPAE--GLLAVTGYNGRGVTTGTVVGKAFADYLLSGE 387
Cdd:TIGR02352 293 PDNLPYIGEHPEdrRLLIATGHYRNGILLAPATAEVIADLILGKE 337
PRK11728 PRK11728
L-2-hydroxyglutarate oxidase;
30-233 1.49e-08

L-2-hydroxyglutarate oxidase;


Pssm-ID: 183292 [Multi-domain]  Cd Length: 393  Bit Score: 56.37  E-value: 1.49e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225   30 DVCVIGAGFTGLSAALHLLEA--GRSVCVLE-AYEVGHGGSGRNVGLINAGTWIPPDEVVATLGAEQGEKLNAVLgrapa 106
Cdd:PRK11728   4 DFVIIGGGIVGLSTAMQLQERypGARIAVLEkESGPARHQTGHNSGVIHAGVYYTPGSLKARFCRRGNEATKAFC----- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225  107 lvmetiERLGID---CqlrreGTLHMSHNASgvaDLQRRHAQWTR---RGAPLELLTGAACHEACGTRRISAALLDRRAG 180
Cdd:PRK11728  79 ------DQHGIPyeeC-----GKLLVATSEL---ELERMEALYERaraNGIEVERLDAEELREREPNIRGLGAIFVPSTG 144

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 15596225  181 TLNPMAYSRGLATAVVQRGGQLYQRSPVLALERQGALWAVRSSAGAVLAEQVV 233
Cdd:PRK11728 145 IVDYRAVAEAMAELIQARGGEIRLGAEVTALDEHANGVVVRTTQGEYEARTLI 197
 
Name Accession Description Interval E-value
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
27-396 4.67e-78

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 246.36  E-value: 4.67e-78
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225  27 QRADVCVIGAGFTGLSAALHLLEAGRSVCVLEAYEVGHGGSGRNVGLINAGtwippdevvatLGAEQGEKLNAVLGRAPA 106
Cdd:COG0665   1 ATADVVVIGGGIAGLSTAYHLARRGLDVTVLERGRPGSGASGRNAGQLRPG-----------LAALADRALVRLAREALD 69

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225 107 LVMETIERLGIDCQLRREGTLHMSHNASGVADLQRRHAQWTRRGAPLELLTGAACHE---ACGTRRISAALLDRRAGTLN 183
Cdd:COG0665  70 LWRELAAELGIDCDFRRTGVLYLARTEAELAALRAEAEALRALGLPVELLDAAELRErepGLGSPDYAGGLYDPDDGHVD 149

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225 184 PMAYSRGLATAVVQRGGQLYQRSPVLALERQGALW-AVRSSAGAVLAEQVVIASNAYTEGEWTNLRRH--FFPGYYYQVA 260
Cdd:COG0665 150 PAKLVRALARAARAAGVRIREGTPVTGLEREGGRVtGVRTERGTVRADAVVLAAGAWSARLLPMLGLRlpLRPVRGYVLV 229

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225 261 SAPLHGaaaeriLPHGQGSWDTRTvlsSIRRDAQGRLLLGS---LGNGANKPAWFLRQWADRIQSHYFPDLGQVNWEYSW 337
Cdd:COG0665 230 TEPLPD------LPLRPVLDDTGV---YLRPTADGRLLVGGtaePAGFDRAPTPERLEALLRRLRRLFPALADAEIVRAW 300

                       330       340       350       360       370       380
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15596225 338 TGCIAFTPDHLMRLFE--PAEGLLAVTGYNGRGVTTGTVVGKAFADYLLSGERATLPLPFS 396
Cdd:COG0665 301 AGLRPMTPDGLPIIGRlpGAPGLYVATGHGGHGVTLAPAAGRLLADLILGGEPPLDLAPFS 361
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 30-381 4.08e-56

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 188.38  E-value: 4.08e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225    30 DVCVIGAGFTGLSAALHLLEAGRSVCVLEAY-EVGHGGSGRNVGLINAGTWIPPDEVVATLGAEqgeklnavlgrAPALV 108
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGLSVTLLERGdDPGSGASGRNAGLIHPGLRYLEPSELARLALE-----------ALDLW 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225   109 METIERLGIDCQLRREGTLHMSHNASGvADLQRRHAQWTRRGAPLELLTGAACHEAC-GTRRISAALLDRRAGTLNPMAY 187
Cdd:pfam01266  70 EELEEELGIDCGFRRCGVLVLARDEEE-EALEKLLAALRRLGVPAELLDAEELRELEpLLPGLRGGLFYPDGGHVDPARL 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225   188 SRGLATAVVQRGGQLYQRSPVLALERQGALWAVRSSAgavLAEQVVIASNAYT-EGEWTNLRRHFFPGYYYQVASAPLHG 266
Cdd:pfam01266 149 LRALARAAEALGVRIIEGTEVTGIEEEGGVWGVVTTG---EADAVVNAAGAWAdLLALPGLRLPVRPVRGQVLVLEPLPE 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225   267 AAAERILPHgqgsWDTRTVLSSIRRDAQGRLLLGS----LGNGANKPAWFLRQWADRIQSHYFPDLGQVnwEYSWTGCIA 342
Cdd:pfam01266 226 ALLILPVPI----TVDPGRGVYLRPRADGRLLLGGtdeeDGFDDPTPDPEEIEELLEAARRLFPALADI--ERAWAGLRP 299

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 15596225   343 fTPDHLMRLFEP-AEGLLAVTGYNGRGVTTGTVVGKAFAD 381
Cdd:pfam01266 300 -LPDGLPIIGRPgSPGLYLATGHGGHGLTLAPGIGKLLAE 338
thiamin_ThiO TIGR02352
glycine oxidase ThiO; This family consists of the homotetrameric, FAD-dependent glycine ...
 47-387 1.09e-10

glycine oxidase ThiO; This family consists of the homotetrameric, FAD-dependent glycine oxidase ThiO, from species such as Bacillus subtilis that use glycine in thiamine biosynthesis. In general, members of this family will not be found in species such as E. coli that instead use tyrosine and the ThiH protein. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine]


Pssm-ID: 274092 [Multi-domain]  Cd Length: 337  Bit Score: 62.77  E-value: 1.09e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225    47 LLEAGRSVCVLEAYEVGHGGSGRNVGLINAGT-WIPPDEVVATLGAEQgeklnavLGRAPALVMETIERLGIDCQLRREG 125
Cdd:TIGR02352   3 LAKRGHSVTLFDRDPMGGGASWAAAGMLAPHAeCEYAEDPLFDLALES-------LRLYPEWLEALKELTGLDTGYHQCG 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225   126 TLHMSHNASGVADLQRRHAQWTRRGAPLELLTGAACH--EACGTRRISAALLDRRAGTLNPMAYSRGLATAVVQRGGQLY 203
Cdd:TIGR02352  76 TLVVAFDEDDVEHLRQLADLQSATGMEVEWLSGRALRrlEPYLSGGIRGAVFYPDDAHVDPRALLKALEKALEKLGVEII 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225   204 QRSPVLALERQGAL-WAVRSSAGAVLAEQVVIASnayteGEWTnlrRHFFPGYYYQVASAPLHGAAAERILPhgqgswdT 282
Cdd:TIGR02352 156 EHTEVQHIEIRGEKvTAIVTPSGDVQADQVVLAA-----GAWA---GELLPLPLRPVRGQPLRLEAPAVPLL-------N 220

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225   283 RTVLSSIRRD-------AQGRLLLGSlgngANKPAWF-----------LRQWADRIqshyFPDLGQVNWEYSWTGCIAFT 344
Cdd:TIGR02352 221 RPLRAVVYGRrvyivprRDGRLVVGA----TMEESGFdttptlggikeLLRDAYTI----LPALKEARLLETWAGLRPGT 292

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 15596225   345 PDHLMRLFEPAE--GLLAVTGYNGRGVTTGTVVGKAFADYLLSGE 387
Cdd:TIGR02352 293 PDNLPYIGEHPEdrRLLIATGHYRNGILLAPATAEVIADLILGKE 337
PRK11728 PRK11728
L-2-hydroxyglutarate oxidase;
30-233 1.49e-08

L-2-hydroxyglutarate oxidase;


Pssm-ID: 183292 [Multi-domain]  Cd Length: 393  Bit Score: 56.37  E-value: 1.49e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225   30 DVCVIGAGFTGLSAALHLLEA--GRSVCVLE-AYEVGHGGSGRNVGLINAGTWIPPDEVVATLGAEQGEKLNAVLgrapa 106
Cdd:PRK11728   4 DFVIIGGGIVGLSTAMQLQERypGARIAVLEkESGPARHQTGHNSGVIHAGVYYTPGSLKARFCRRGNEATKAFC----- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225  107 lvmetiERLGID---CqlrreGTLHMSHNASgvaDLQRRHAQWTR---RGAPLELLTGAACHEACGTRRISAALLDRRAG 180
Cdd:PRK11728  79 ------DQHGIPyeeC-----GKLLVATSEL---ELERMEALYERaraNGIEVERLDAEELREREPNIRGLGAIFVPSTG 144

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 15596225  181 TLNPMAYSRGLATAVVQRGGQLYQRSPVLALERQGALWAVRSSAGAVLAEQVV 233
Cdd:PRK11728 145 IVDYRAVAEAMAELIQARGGEIRLGAEVTALDEHANGVVVRTTQGEYEARTLI 197
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 30-79 3.60e-07

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 52.17  E-value: 3.60e-07
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 15596225  30 DVCVIGAGFTGLSAALHLLEAGRSVCVLEAyevghggsGRNVGlinaGTW 79
Cdd:COG2072   8 DVVVIGAGQAGLAAAYHLRRAGIDFVVLEK--------ADDVG----GTW 45
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 27-62 7.56e-07

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 51.00  E-value: 7.56e-07
                        10        20        30
                ....*....|....*....|....*....|....*.
gi 15596225  27 QRADVCVIGAGFTGLSAALHLLEAGRSVCVLEAYEV 62
Cdd:COG1233   2 MMYDVVVIGAGIGGLAAAALLARAGYRVTVLEKNDT 37
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
28-118 1.71e-06

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 49.92  E-value: 1.71e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225  28 RADVCVIGAGFTGLSAALHLLEAGRSVCVLEA-YEVGhggsGRNVGLINAGTWIPPDevvatLGAEQgeklnavLGRAPA 106
Cdd:COG1231   7 GKDVVIVGAGLAGLAAARELRKAGLDVTVLEArDRVG----GRVWTLRFGDDGLYAE-----LGAMR-------IPPSHT 70

                        90
                ....*....|..
gi 15596225 107 LVMETIERLGID 118
Cdd:COG1231  71 NLLALARELGLP 82
solA PRK11259
N-methyl-L-tryptophan oxidase;
27-240 1.71e-06

N-methyl-L-tryptophan oxidase;


Pssm-ID: 236887 [Multi-domain]  Cd Length: 376  Bit Score: 49.83  E-value: 1.71e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225   27 QRADVCVIGAGFTGLSAALHLLEAGRSVCVLEAYEVGHG-GS--GRN------VG--------LINAGT-WippDEvvat 88
Cdd:PRK11259   2 MRYDVIVIGLGSMGSAAGYYLARRGLRVLGLDRFMPPHQqGSshGDTriirhaYGegpayvplVLRAQElW---RE---- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225   89 LGAEQGEKLnavlgrapalvmetierlgidcqLRREGTLHMSHNAS----GVADLQRRHaqwtrrGAPLELLTGAACHEA 164
Cdd:PRK11259  75 LERESGEPL-----------------------FVRTGVLNLGPADSdflaNSIRSARQH------GLPHEVLDAAEIRRR 125

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15596225  165 CGTRRISA---ALLDRRAGTLNPMAYSRGLATAVVQRGGQLYQRSPVLALERQGALWAVRSSAGAVLAEQVVIASNAYT 240
Cdd:PRK11259 126 FPQFRLPDgyiALFEPDGGFLRPELAIKAHLRLAREAGAELLFNEPVTAIEADGDGVTVTTADGTYEAKKLVVSAGAWV 204
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 28-59 3.04e-06

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 49.06  E-value: 3.04e-06
                        10        20        30
                ....*....|....*....|....*....|..
gi 15596225  28 RADVCVIGAGFTGLSAALHLLEAGRSVCVLEA 59
Cdd:COG1232   1 MKRVAVIGGGIAGLTAAYRLAKAGHEVTVLEA 32
SdhA COG1053
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and ...
 26-76 8.73e-06

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440673 [Multi-domain]  Cd Length: 443  Bit Score: 47.91  E-value: 8.73e-06
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|.
gi 15596225  26 EQRADVCVIGAGFTGLSAALHLLEAGRSVCVLEAYEVGHGGSGRNVGLINA 76
Cdd:COG1053   1 DHEYDVVVVGSGGAGLRAALEAAEAGLKVLVLEKVPPRGGHTAAAQGGINA 51
PRK07233 PRK07233
hypothetical protein; Provisional
 31-66 1.65e-05

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 46.80  E-value: 1.65e-05
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 15596225   31 VCVIGAGFTGLSAALHLLEAGRSVCVLEAYEVgHGG 66
Cdd:PRK07233   2 IAIVGGGIAGLAAAYRLAKRGHEVTVFEADDQ-LGG 36
mnmC PRK01747
bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent ...
 30-239 2.93e-05

bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC;


Pssm-ID: 234978 [Multi-domain]  Cd Length: 662  Bit Score: 46.38  E-value: 2.93e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225   30 DVCVIGAGFTGLSAALHLLEAGRSVCVLEAYE-VGHGGSGRNVG----LINAgtwipPDEVVATLgaeqgeklnAVLGRA 104
Cdd:PRK01747 262 DAAIIGGGIAGAALALALARRGWQVTLYEADEaPAQGASGNRQGalypLLSK-----DDNALSRF---------FRAAFL 327

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225  105 PAL-VMETIERLGIDCQLRREGTLHMSHNasgvADLQRRHAQWTRRGAPLELLTGAACHEAcgtRRISAALLDR------ 177
Cdd:PRK01747 328 FARrFYDALPAAGVAFDHDWCGVLQLAWD----EKSAEKIAKMLALGLPAELARALDAEEA---EELAGLPVPCggifyp 400

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15596225  178 RAGTLNPMAYSRGLATAvVQRGGQLYQRSPVLALERQGALWAVRSSAGAVLAEQVVIASNAY 239
Cdd:PRK01747 401 QGGWLCPAELCRALLAL-AGQQLTIHFGHEVARLEREDDGWQLDFAGGTLASAPVVVLANGH 461
PRK07804 PRK07804
L-aspartate oxidase; Provisional
 13-57 2.93e-05

L-aspartate oxidase; Provisional


Pssm-ID: 236102 [Multi-domain]  Cd Length: 541  Bit Score: 46.12  E-value: 2.93e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 15596225   13 VTPRLSGAASLNGEQRADVCVIGAGFTGLSAALHLLEAGRSVCVL 57
Cdd:PRK07804   1 ALPRRLAAPAPGWRDAADVVVVGSGVAGLTAALAARRAGRRVLVV 45
crtI_fam TIGR02734
phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two ...
 31-59 3.15e-05

phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two symmetrical pairs of) sites. This is achieved by two enzymes (crtP and crtQ) in cyanobacteria (Gloeobacter being an exception) and plants, but by a single enzyme in most other bacteria and in fungi. This single enzyme is called the bacterial-type phytoene desaturase, or CrtI. Most members of this family, part of the larger pfam01593, which also contains amino oxidases, are CrtI itself; it is likely that all members act on either phytoene or on related compounds such as dehydrosqualene, for carotenoid biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 274273 [Multi-domain]  Cd Length: 495  Bit Score: 46.12  E-value: 3.15e-05
                          10        20
                  ....*....|....*....|....*....
gi 15596225    31 VCVIGAGFTGLSAALHLLEAGRSVCVLEA 59
Cdd:TIGR02734   1 AVVIGAGFGGLALAIRLAAAGIPVTVVEQ 29
COG3349 COG3349
Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function ...
 28-59 5.39e-05

Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function prediction only];


Pssm-ID: 442577 [Multi-domain]  Cd Length: 445  Bit Score: 45.23  E-value: 5.39e-05
                        10        20        30
                ....*....|....*....|....*....|..
gi 15596225  28 RADVCVIGAGFTGLSAALHLLEAGRSVCVLEA 59
Cdd:COG3349   3 PPRVVVVGGGLAGLAAAVELAEAGFRVTLLEA 34
COG3573 COG3573
Predicted oxidoreductase [General function prediction only];
25-58 7.84e-05

Predicted oxidoreductase [General function prediction only];


Pssm-ID: 442794 [Multi-domain]  Cd Length: 551  Bit Score: 44.78  E-value: 7.84e-05
                        10        20        30
                ....*....|....*....|....*....|....
gi 15596225  25 GEQRADVCVIGAGFTGLSAALHLLEAGRSVCVLE 58
Cdd:COG3573   2 AAMDADVIVVGAGLAGLVAAAELADAGRRVLLLD 35
PRK12843 PRK12843
FAD-dependent oxidoreductase;
14-111 2.02e-04

FAD-dependent oxidoreductase;


Pssm-ID: 237225 [Multi-domain]  Cd Length: 578  Bit Score: 43.57  E-value: 2.02e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225   14 TPRLSGAASLNGEQRADVCVIGAGFTGLSAALHLLEAGRSVCVLEAYEVGHGGSGRNVGlinaGTWIPPDEVVATLGA-- 91
Cdd:PRK12843   2 SPVVSELSPERWDAEFDVIVIGAGAAGMSAALFAAIAGLKVLLVERTEYVGGTTATSAG----TTWIPGTRHGLAVGPdd 77

                         90       100
                 ....*....|....*....|....
gi 15596225   92 --EQGEK-LNAVLG-RAPALVMET 111
Cdd:PRK12843  78 slEAARTyLDALVGdRSPEELRDA 101
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 28-179 2.63e-04

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 42.70  E-value: 2.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225    28 RADVCVIGAGFTGLSAALHLLEAGRSVCVLEAYEVGHGGSgRNVGLiNAGTwippdevvatlgaeqgeklnavlgrapal 107
Cdd:pfam01494   1 ETDVLIVGGGPAGLMLALLLARAGVRVVLVERHATTSVLP-RAHGL-NQRT----------------------------- 49

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15596225   108 vMETIERLGIDCQLRREGTLH--MSHNASGvadlqrrhaqwTRRGAPLELLTGAACHEACGTRRISAALLDRRA 179
Cdd:pfam01494  50 -MELLRQAGLEDRILAEGVPHegMGLAFYN-----------TRRRADLDFLTSPPRVTVYPQTELEPILVEHAE 111
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
30-63 3.40e-04

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 42.41  E-value: 3.40e-04
                        10        20        30
                ....*....|....*....|....*....|....
gi 15596225  30 DVCVIGAGFTGLSAALHLLEAGRSVCVLEAYEVG 63
Cdd:COG0492   2 DVVIIGAGPAGLTAAIYAARAGLKTLVIEGGEPG 35
FAD_binding_2 pfam00890
FAD binding domain; This family includes members that bind FAD. This family includes the ...
 30-230 6.36e-04

FAD binding domain; This family includes members that bind FAD. This family includes the flavoprotein subunits from succinate and fumarate dehydrogenase, aspartate oxidase and the alpha subunit of adenylylsulphate reductase.


Pssm-ID: 395718 [Multi-domain]  Cd Length: 398  Bit Score: 41.89  E-value: 6.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225    30 DVCVIGAGFTGLSAALHLLEAGRSVCVLEAYEVGHGGSGRNVGLINA---GTWIPPDEVVA------TLGAEQGEKLNAV 100
Cdd:pfam00890   1 DVLVIGGGLAGLAAALAAAEAGLKVAVVEKGQPFGGATAWSSGGIDAlgnPPQGGIDSPELhptdtlKGLDELADHPYVE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225   101 LG--RAPALVMEtIERLGIDCQLRREGTLHMSHNAsgvADLQRRHAQWTRRGAPLELLTGAACheacgtrrisAALLDRR 178
Cdd:pfam00890  81 AFveAAPEAVDW-LEALGVPFSRTEDGHLDLRPLG---GLSATWRTPHDAADRRRGLGTGHAL----------LARLLEG 146

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 15596225   179 AGTLNPMAYSRGLATAVVQRGGQLyqRSPVLALERQGALWAVRSSAGAVLAE 230
Cdd:pfam00890 147 LRKAGVDFQPRTAADDLIVEDGRV--TGAVVENRRNGREVRIRAIAAVLLAT 196
PRK12834 PRK12834
putative FAD-binding dehydrogenase; Reviewed
 29-58 1.16e-03

putative FAD-binding dehydrogenase; Reviewed


Pssm-ID: 183782 [Multi-domain]  Cd Length: 549  Bit Score: 41.04  E-value: 1.16e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 15596225   29 ADVCVIGAGFTGLSAALHLLEAGRSVCVLE 58
Cdd:PRK12834   5 ADVIVVGAGLAGLVAAAELADAGKRVLLLD 34
PLN02976 PLN02976
amine oxidase
 26-59 1.19e-03

amine oxidase


Pssm-ID: 215527 [Multi-domain]  Cd Length: 1713  Bit Score: 41.39  E-value: 1.19e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 15596225    26 EQRADVCVIGAGFTGLSAALHLLEAGRSVCVLEA 59
Cdd:PLN02976  691 VDRKKIIVVGAGPAGLTAARHLQRQGFSVTVLEA 724
PRK06753 PRK06753
hypothetical protein; Provisional
 31-114 1.32e-03

hypothetical protein; Provisional


Pssm-ID: 168661 [Multi-domain]  Cd Length: 373  Bit Score: 40.83  E-value: 1.32e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225   31 VCVIGAGFTGLSAALHLLEAGRSVCVLEAY----EVGHG-GSGRNV-----------GLINAGTWIPPDEVVatlgAEQG 94
Cdd:PRK06753   3 IAIIGAGIGGLTAAALLQEQGHEVKVFEKNesvkEVGAGiGIGDNVikklgnhdlakGIKNAGQILSTMNLL----DDKG 78

                         90       100
                 ....*....|....*....|
gi 15596225   95 EKLNAVlGRAPALVMETIER 114
Cdd:PRK06753  79 TLLNKV-KLKSNTLNVTLHR 97
PRK08274 PRK08274
FAD-dependent tricarballylate dehydrogenase TcuA;
30-59 1.72e-03

FAD-dependent tricarballylate dehydrogenase TcuA;


Pssm-ID: 236214 [Multi-domain]  Cd Length: 466  Bit Score: 40.63  E-value: 1.72e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 15596225   30 DVCVIGAGFTGLSAALHLLEAGRSVCVLEA 59
Cdd:PRK08274   6 DVLVIGGGNAALCAALAAREAGASVLLLEA 35
PRK07843 PRK07843
3-oxosteroid 1-dehydrogenase;
26-90 1.94e-03

3-oxosteroid 1-dehydrogenase;


Pssm-ID: 236111 [Multi-domain]  Cd Length: 557  Bit Score: 40.40  E-value: 1.94e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15596225   26 EQRADVCVIGAGFTGLSAALHLLEAGRSVCVLEayEVGH-GGSGRNVGlinAGTWIPPDEVVATLG 90
Cdd:PRK07843   5 VQEYDVVVVGSGAAGMVAALTAAHRGLSTVVVE--KAPHyGGSTARSG---GGVWIPNNEVLKRAG 65
PRK07208 PRK07208
hypothetical protein; Provisional
 26-59 2.38e-03

hypothetical protein; Provisional


Pssm-ID: 235967 [Multi-domain]  Cd Length: 479  Bit Score: 40.26  E-value: 2.38e-03
                         10        20        30
                 ....*....|....*....|....*....|....
gi 15596225   26 EQRADVCVIGAGFTGLSAALHLLEAGRSVCVLEA 59
Cdd:PRK07208   2 TNKKSVVIIGAGPAGLTAAYELLKRGYPVTVLEA 35
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
33-59 2.83e-03

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 35.97  E-value: 2.83e-03
                          10        20
                  ....*....|....*....|....*..
gi 15596225    33 VIGAGFTGLSAALHLLEAGRSVCVLEA 59
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEK 27
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 30-59 5.60e-03

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 38.45  E-value: 5.60e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 15596225    30 DVCVIGAGFTGLSAALHLLEAGRSVCVLEA 59
Cdd:pfam07992   2 DVVVIGGGPAGLAAALTLAQLGGKVTLIED 31
PLN02464 PLN02464
glycerol-3-phosphate dehydrogenase
 11-77 6.04e-03

glycerol-3-phosphate dehydrogenase


Pssm-ID: 215257 [Multi-domain]  Cd Length: 627  Bit Score: 38.99  E-value: 6.04e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596225   11 EVVTPRLSGAASLNGEQRA---DVCVIGAGFTGLSAALHLLEAGRSVCVLEAYEVGHGGSGRNVGLINAG 77
Cdd:PLN02464  51 ASVPSRSAQESALIGATAAeplDVLVVGGGATGAGVALDAATRGLRVGLVEREDFSSGTSSRSTKLIHGG 120
PRK05329 PRK05329
glycerol-3-phosphate dehydrogenase subunit GlpB;
28-57 9.66e-03

glycerol-3-phosphate dehydrogenase subunit GlpB;


Pssm-ID: 235412  Cd Length: 422  Bit Score: 37.91  E-value: 9.66e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 15596225   28 RADVCVIGAGFTGLSAALHLLEAGRSVCVL 57
Cdd:PRK05329   2 KFDVLVIGGGLAGLTAALAAAEAGKRVALV 31
NadB COG0029
Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the ...
 26-57 9.99e-03

Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the Pathway/BioSystem: NAD biosynthesis


Pssm-ID: 439800 [Multi-domain]  Cd Length: 521  Bit Score: 38.16  E-value: 9.99e-03
                        10        20        30
                ....*....|....*....|....*....|..
gi 15596225  26 EQRADVCVIGAGFTGLSAALHLLEAGRsVCVL 57
Cdd:COG0029   2 RLKTDVLVIGSGIAGLSAALKLAERGR-VTLL 32
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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