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Conserved domains on  [gi|15595740|ref|NP_249234|]
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hypothetical protein PA0543 [Pseudomonas aeruginosa PAO1]

Protein Classification

alpha/beta hydrolase family esterase( domain architecture ID 10007502)

alpha/beta hydrolase family esterase such as Aspergillus acetylxylan esterase A that is involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass

CATH:  3.40.50.1820
EC:  3.1.1.-
Gene Ontology:  GO:0052689
PubMed:  19508187|31545554|37582413|12369917

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LpqC COG3509
Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and ...
 31-319 1.42e-70

Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and metabolism];


:

Pssm-ID: 442732 [Multi-domain]  Cd Length: 284  Bit Score: 220.65  E-value: 1.42e-70
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595740  31 ALRPPALAGHSEDSSLKVAGLRRHYLLYVPPGV--SEGAPLLVVLHGSRGDGAQMRRisGYGFDRLAAQEGFLVAYPDGF 108
Cdd:COG3509  15 ALLPAAAAAGDFERTFTVGGGTRTYRLYVPAGYdgGAPLPLVVALHGCGGSAADFAA--GTGLNALADREGFIVVYPEGT 92

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595740 109 EGHWNDCRKAASYSARLRDVDDVAFLRALVARLAQEYRVDSQRVYVAGYSNGGQMAFRLAAEAP----------GLPAAi 178
Cdd:COG3509  93 GRAPGRCWNWFDGRDQRRGRDDVAFIAALVDDLAARYGIDPKRVYVTGLSAGGAMAYRLACEYPdvfaavapvaGLPYG- 171

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595740 179 aavaaslpTTGNDACRPvERPTAALLINGTRDPINPYLGGKvslfgfgdrgavrstlDSARWWAGLNGIAAPPDVAPLTR 258
Cdd:COG3509 172 --------AASDAACAP-GRPVPVLVIHGTADPTVPYAGAE----------------ETLAQWAALNGCAATPTRTEVTD 226

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15595740 259 PGPVwtERQRWQ-EDGHPPVELLSVHGGGHVLAQPDYRFPrilGKSDPELDAPVEIWRFFSQ 319
Cdd:COG3509 227 GGGY--TRTRYSdCAGGAEVELYTVEGGGHAWPGGGAAGP---YTDPRGIDASEEIWRFFGA 283
 
Name Accession Description Interval E-value
LpqC COG3509
Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and ...
 31-319 1.42e-70

Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and metabolism];


Pssm-ID: 442732 [Multi-domain]  Cd Length: 284  Bit Score: 220.65  E-value: 1.42e-70
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595740  31 ALRPPALAGHSEDSSLKVAGLRRHYLLYVPPGV--SEGAPLLVVLHGSRGDGAQMRRisGYGFDRLAAQEGFLVAYPDGF 108
Cdd:COG3509  15 ALLPAAAAAGDFERTFTVGGGTRTYRLYVPAGYdgGAPLPLVVALHGCGGSAADFAA--GTGLNALADREGFIVVYPEGT 92

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595740 109 EGHWNDCRKAASYSARLRDVDDVAFLRALVARLAQEYRVDSQRVYVAGYSNGGQMAFRLAAEAP----------GLPAAi 178
Cdd:COG3509  93 GRAPGRCWNWFDGRDQRRGRDDVAFIAALVDDLAARYGIDPKRVYVTGLSAGGAMAYRLACEYPdvfaavapvaGLPYG- 171

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595740 179 aavaaslpTTGNDACRPvERPTAALLINGTRDPINPYLGGKvslfgfgdrgavrstlDSARWWAGLNGIAAPPDVAPLTR 258
Cdd:COG3509 172 --------AASDAACAP-GRPVPVLVIHGTADPTVPYAGAE----------------ETLAQWAALNGCAATPTRTEVTD 226

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15595740 259 PGPVwtERQRWQ-EDGHPPVELLSVHGGGHVLAQPDYRFPrilGKSDPELDAPVEIWRFFSQ 319
Cdd:COG3509 227 GGGY--TRTRYSdCAGGAEVELYTVEGGGHAWPGGGAAGP---YTDPRGIDASEEIWRFFGA 283
Esterase_PHB pfam10503
Esterase PHB depolymerase; This family of proteins include acetyl xylan esterases (AXE), ...
 55-172 1.48e-10

Esterase PHB depolymerase; This family of proteins include acetyl xylan esterases (AXE), feruloyl esterases (FAE), and poly(3-hydroxybutyrate) (PHB) depolymerases.


Pssm-ID: 431322 [Multi-domain]  Cd Length: 222  Bit Score: 60.07  E-value: 1.48e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595740    55 YLLYVPPGVS---EGAPLLVVLHGSRGDGAQMrrISGYGFDRLAAQEGFLVAYPDGFE-GHWNDCRKAASYSARLRDVDD 130
Cdd:pfam10503   3 YALYLPPEAAgdgAPMPLVVMLHGCKQHADDF--AAGTRINALADELGFAVLYPEQSKhAHAHKCWNWFDEQGAARGGGE 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 15595740   131 VAFLRALVARLAQEYRVDSQRVYVAGYSNGGQMAFRLAAEAP 172
Cdd:pfam10503  81 AASIAALAKAIAAAHRLDGARVYLAGLSAGAALAALLAHCYP 122
esterase_phb TIGR01840
esterase, PHB depolymerase family; This model describes a subfamily among lipases of the ...
 55-172 1.26e-09

esterase, PHB depolymerase family; This model describes a subfamily among lipases of the ab-hydrolase family. This subfamily includes bacterial depolymerases for poly(3-hydroxybutyrate) (PHB) and related polyhydroxyalkanoates (PHA), as well as acetyl xylan esterases, feruloyl esterases, and others from fungi. [Fatty acid and phospholipid metabolism, Degradation]


Pssm-ID: 273828 [Multi-domain]  Cd Length: 212  Bit Score: 57.11  E-value: 1.26e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595740    55 YLLYVPPGVSEGAPLLVVLHGSRGDGAQMrrISGYGFDRLAAQEGFLVAYPDGFEG-HWNDCRKAASYSARLRDVDDVAF 133
Cdd:TIGR01840   1 MYVYVPAGLTGPRALVLALHGCGQTASAY--VIDWGWKAAADRYGFVLVAPEQTSYnSSNNCWDWFFTHHRARGTGEVES 78

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 15595740   134 LRALVARLAQEYRVDSQRVYVAGYSNGGQMAFRLAAEAP 172
Cdd:TIGR01840  79 LHQLIDAVKANYSIDPNRVYVTGLSAGGGMTAVLGCTYP 117
 
Name Accession Description Interval E-value
LpqC COG3509
Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and ...
 31-319 1.42e-70

Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and metabolism];


Pssm-ID: 442732 [Multi-domain]  Cd Length: 284  Bit Score: 220.65  E-value: 1.42e-70
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595740  31 ALRPPALAGHSEDSSLKVAGLRRHYLLYVPPGV--SEGAPLLVVLHGSRGDGAQMRRisGYGFDRLAAQEGFLVAYPDGF 108
Cdd:COG3509  15 ALLPAAAAAGDFERTFTVGGGTRTYRLYVPAGYdgGAPLPLVVALHGCGGSAADFAA--GTGLNALADREGFIVVYPEGT 92

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595740 109 EGHWNDCRKAASYSARLRDVDDVAFLRALVARLAQEYRVDSQRVYVAGYSNGGQMAFRLAAEAP----------GLPAAi 178
Cdd:COG3509  93 GRAPGRCWNWFDGRDQRRGRDDVAFIAALVDDLAARYGIDPKRVYVTGLSAGGAMAYRLACEYPdvfaavapvaGLPYG- 171

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595740 179 aavaaslpTTGNDACRPvERPTAALLINGTRDPINPYLGGKvslfgfgdrgavrstlDSARWWAGLNGIAAPPDVAPLTR 258
Cdd:COG3509 172 --------AASDAACAP-GRPVPVLVIHGTADPTVPYAGAE----------------ETLAQWAALNGCAATPTRTEVTD 226

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15595740 259 PGPVwtERQRWQ-EDGHPPVELLSVHGGGHVLAQPDYRFPrilGKSDPELDAPVEIWRFFSQ 319
Cdd:COG3509 227 GGGY--TRTRYSdCAGGAEVELYTVEGGGHAWPGGGAAGP---YTDPRGIDASEEIWRFFGA 283
COG4099 COG4099
Predicted peptidase [General function prediction only];
47-174 4.98e-18

Predicted peptidase [General function prediction only];


Pssm-ID: 443275 [Multi-domain]  Cd Length: 235  Bit Score: 81.55  E-value: 4.98e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595740  47 KVAGLRRHYLLYVPPGVSEG--APLLVVLHGSRGDGAQMRRISGYGFDRLA-----AQEGFLVAYPDgfeghwndCRKAA 119
Cdd:COG4099  27 PSDGDTLPYRLYLPKGYDPGkkYPLVLFLHGAGERGTDNEKQLTHGAPKFInpenqAKFPAIVLAPQ--------CPEDD 98

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*
gi 15595740 120 SYSARlrdvDDVAFLRALVARLAQEYRVDSQRVYVAGYSNGGQMAFRLAAEAPGL 174
Cdd:COG4099  99 YWSDT----KALDAVLALLDDLIAEYRIDPDRIYLTGLSMGGYGTWDLAARYPDL 149
YpfH COG0400
Predicted esterase [General function prediction only];
64-215 6.75e-12

Predicted esterase [General function prediction only];


Pssm-ID: 440169 [Multi-domain]  Cd Length: 200  Bit Score: 63.39  E-value: 6.75e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595740  64 SEGAPLLVVLHGSRGDGAQMRRIsgygFDRLAaQEGFLVAYPDGFEGHWNDCRK--AASYSARLRDVDDV----AFLRAL 137
Cdd:COG0400   2 GPAAPLVVLLHGYGGDEEDLLPL----APELA-LPGAAVLAPRAPVPEGPGGRAwfDLSFLEGREDEEGLaaaaEALAAF 76

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595740 138 VARLAQEYRVDSQRVYVAGYSNGGQMAFRLAAEAP-----------GLPAAIAAVAASLPTTGndacRPVerptaaLLIN 206
Cdd:COG0400  77 IDELEARYGIDPERIVLAGFSQGAAMALSLALRRPellagvvalsgYLPGEEALPAPEAALAG----TPV------FLAH 146


                ....*....
gi 15595740 207 GTRDPINPY 215
Cdd:COG0400 147 GTQDPVIPV 155
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
50-174 1.47e-11

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 63.11  E-value: 1.47e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595740  50 GLRRHYLLYVPPGvSEGAPLLVVLHGsrGDGAQMRrisgyGFDRLA---AQEGFLVAYPDGFeGHWNDCRKAASYsarlr 126
Cdd:COG1506   7 GTTLPGWLYLPAD-GKKYPVVVYVHG--GPGSRDD-----SFLPLAqalASRGYAVLAPDYR-GYGESAGDWGGD----- 72

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*...
gi 15595740 127 DVDDVAflrALVARLAQEYRVDSQRVYVAGYSNGGQMAFRLAAEAPGL 174
Cdd:COG1506  73 EVDDVL---AAIDYLAARPYVDPDRIGIYGHSYGGYMALLAAARHPDR 117
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
57-174 2.07e-11

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 62.68  E-value: 2.07e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595740  57 LYVPPGvSEGAPLLVVLHGSRGDGAQMRRISgygfDRLAAqEGFLVAYPD--GFEGHWNDCRKAASYSARLRDVDDVAFL 134
Cdd:COG0412  20 LARPAG-GGPRPGVVVLHEIFGLNPHIRDVA----RRLAA-AGYVVLAPDlyGRGGPGDDPDEARALMGALDPELLAADL 93

                        90       100       110       120
                ....*....|....*....|....*....|....*....|
gi 15595740 135 RALVARLAQEYRVDSQRVYVAGYSNGGQMAFRLAAEAPGL 174
Cdd:COG0412  94 RAALDWLKAQPEVDAGRVGVVGFCFGGGLALLAAARGPDL 133
Esterase_PHB pfam10503
Esterase PHB depolymerase; This family of proteins include acetyl xylan esterases (AXE), ...
 55-172 1.48e-10

Esterase PHB depolymerase; This family of proteins include acetyl xylan esterases (AXE), feruloyl esterases (FAE), and poly(3-hydroxybutyrate) (PHB) depolymerases.


Pssm-ID: 431322 [Multi-domain]  Cd Length: 222  Bit Score: 60.07  E-value: 1.48e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595740    55 YLLYVPPGVS---EGAPLLVVLHGSRGDGAQMrrISGYGFDRLAAQEGFLVAYPDGFE-GHWNDCRKAASYSARLRDVDD 130
Cdd:pfam10503   3 YALYLPPEAAgdgAPMPLVVMLHGCKQHADDF--AAGTRINALADELGFAVLYPEQSKhAHAHKCWNWFDEQGAARGGGE 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 15595740   131 VAFLRALVARLAQEYRVDSQRVYVAGYSNGGQMAFRLAAEAP 172
Cdd:pfam10503  81 AASIAALAKAIAAAHRLDGARVYLAGLSAGAALAALLAHCYP 122
esterase_phb TIGR01840
esterase, PHB depolymerase family; This model describes a subfamily among lipases of the ...
 55-172 1.26e-09

esterase, PHB depolymerase family; This model describes a subfamily among lipases of the ab-hydrolase family. This subfamily includes bacterial depolymerases for poly(3-hydroxybutyrate) (PHB) and related polyhydroxyalkanoates (PHA), as well as acetyl xylan esterases, feruloyl esterases, and others from fungi. [Fatty acid and phospholipid metabolism, Degradation]


Pssm-ID: 273828 [Multi-domain]  Cd Length: 212  Bit Score: 57.11  E-value: 1.26e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595740    55 YLLYVPPGVSEGAPLLVVLHGSRGDGAQMrrISGYGFDRLAAQEGFLVAYPDGFEG-HWNDCRKAASYSARLRDVDDVAF 133
Cdd:TIGR01840   1 MYVYVPAGLTGPRALVLALHGCGQTASAY--VIDWGWKAAADRYGFVLVAPEQTSYnSSNNCWDWFFTHHRARGTGEVES 78

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 15595740   134 LRALVARLAQEYRVDSQRVYVAGYSNGGQMAFRLAAEAP 172
Cdd:TIGR01840  79 LHQLIDAVKANYSIDPNRVYVTGLSAGGGMTAVLGCTYP 117
Fes COG2382
Enterochelin esterase or related enzyme [Inorganic ion transport and metabolism];
47-174 8.56e-08

Enterochelin esterase or related enzyme [Inorganic ion transport and metabolism];


Pssm-ID: 441948 [Multi-domain]  Cd Length: 314  Bit Score: 52.93  E-value: 8.56e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595740  47 KVAGLRRHYLLYVPPG---VSEGAPLLVVLHGSRGDGAQMRRISGYG--FDRLAAQ---EGFLVAYPDGfeghwNDCRKA 118
Cdd:COG2382  89 KALGRTRRVWVYLPPGydnPGKKYPVLYLLDGGGGDEQDWFDQGRLPtiLDNLIAAgkiPPMIVVMPDG-----GDGGDR 163

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 15595740 119 ASYSARLRDVDDvAFLRALVARLAQEYRV--DSQRVYVAGYSNGGQMAFRLAAEAPGL 174
Cdd:COG2382 164 GTEGPGNDAFER-FLAEELIPFVEKNYRVsaDPEHRAIAGLSMGGLAALYAALRHPDL 220
Aes COG0657
Acetyl esterase/lipase [Lipid transport and metabolism];
57-171 1.65e-07

Acetyl esterase/lipase [Lipid transport and metabolism];


Pssm-ID: 440422 [Multi-domain]  Cd Length: 207  Bit Score: 51.03  E-value: 1.65e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595740  57 LYVPPGVSEGAPLLVVLHG---SRGDGAQMRRISgygfDRLAAQEGFLVAYPDgfeghwndCRKA--ASYSARLRDVDDV 131
Cdd:COG0657   3 VYRPAGAKGPLPVVVYFHGggwVSGSKDTHDPLA----RRLAARAGAAVVSVD--------YRLApeHPFPAALEDAYAA 70

                        90       100       110       120
                ....*....|....*....|....*....|....*....|
gi 15595740 132 afLRALVARlAQEYRVDSQRVYVAGYSNGGQMAFRLAAEA 171
Cdd:COG0657  71 --LRWLRAN-AAELGIDPDRIAVAGDSAGGHLAAALALRA 107
DLH pfam01738
Dienelactone hydrolase family;
56-174 7.11e-06

Dienelactone hydrolase family;


Pssm-ID: 396343 [Multi-domain]  Cd Length: 213  Bit Score: 46.19  E-value: 7.11e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595740    56 LLYVPPGVSEgaPLLVVLHGSRGDGAQMRRISgygfDRLAaQEGFLVAYPD--GFEGHWNDCRKAAS-YSARLRDVDD-- 130
Cdd:pfam01738   3 YLATPKNPPW--PVVVVFQEIFGVNDNIREIA----DRLA-DEGYVALAPDlyFRQGDPNDEADAARaMFELVSKRVMek 75

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 15595740   131 -VAFLRALVARLAQEYRVDSQRVYVAGYSNGGQMAFRLAAEAPGL 174
Cdd:pfam01738  76 vLDDLEAAVNYLKSQPEVSPKKVGVVGYCMGGALAVLLAAKGPLV 120
YheT COG0429
Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];
66-172 2.00e-05

Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];


Pssm-ID: 440198 [Multi-domain]  Cd Length: 323  Bit Score: 45.52  E-value: 2.00e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595740  66 GAPLLVVLHGSRGDgAQmrriSGY--GFDRLAAQEGFLVAYPdgfegHWNDC-----RKAASYSARlrDVDDVaflRALV 138
Cdd:COG0429  60 SKPLVVLLHGLEGS-SD----SHYarGLARALYARGWDVVRL-----NFRGCggepnLLPRLYHSG--DTEDL---VWVL 124

                        90       100       110
                ....*....|....*....|....*....|....
gi 15595740 139 ARLAQEYRvdSQRVYVAGYSNGGQMAFRLAAEAP 172
Cdd:COG0429 125 AHLRARYP--YAPLYAVGFSLGGNLLLKYLGEQG 156
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
 57-172 3.28e-05

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 44.52  E-value: 3.28e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595740  57 LYVPPGVSEGAPLLVVLHGSRGDGAQMrriSGYGfDRLAAQeGFLVAYPD--GF---EGHWndcRKAASYsaRLRDVddv 131
Cdd:COG1073  27 LYLPAGASKKYPAVVVAHGNGGVKEQR---ALYA-QRLAEL-GFNVLAFDyrGYgesEGEP---REEGSP--ERRDA--- 93

                        90       100       110       120
                ....*....|....*....|....*....|....*....|.
gi 15595740 132 aflRALVARLAQEYRVDSQRVYVAGYSNGGQMAFRLAAEAP 172
Cdd:COG1073  94 ---RAAVDYLRTLPGVDPERIGLLGISLGGGYALNAAATDP 131
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 46-174 5.33e-05

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 43.84  E-value: 5.33e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595740  46 LKVAGLRRHYLLYVPPGvsegaPLLVVLHGSRGDGAQMRRIsgygFDRLAaqEGFLVAYPDgFEGHWNDCRKAASYSARl 125
Cdd:COG0596   7 VTVDGVRLHYREAGPDG-----PPVVLLHGLPGSSYEWRPL----IPALA--AGYRVIAPD-LRGHGRSDKPAGGYTLD- 73

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*....
gi 15595740 126 rdvDDVAFLRALVARLaqeyrvDSQRVYVAGYSNGGQMAFRLAAEAPGL 174
Cdd:COG0596  74 ---DLADDLAALLDAL------GLERVVLVGHSMGGMVALELAARHPER 113
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
71-174 3.95e-04

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 41.08  E-value: 3.95e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595740  71 VVLHGSRGDGAQMRRISgygfdRLAAQEGFLVAYPDgFEGH-----------WNDCRKAAsysarlrdvddvaflRALVA 139
Cdd:COG1647  19 LLLHGFTGSPAEMRPLA-----EALAKAGYTVYAPR-LPGHgtspedllkttWEDWLEDV---------------EEAYE 77

                        90       100       110
                ....*....|....*....|....*....|....*
gi 15595740 140 RLAQEYRvdsqRVYVAGYSNGGQMAFRLAAEAPGL 174
Cdd:COG1647  78 ILKAGYD----KVIVIGLSMGGLLALLLAARYPDV 108
Peptidase_S9 pfam00326
Prolyl oligopeptidase family;
94-174 5.96e-04

Prolyl oligopeptidase family;


Pssm-ID: 459761 [Multi-domain]  Cd Length: 213  Bit Score: 40.29  E-value: 5.96e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595740    94 LAAQEGFLVAYPD----GFEGH-WNDcrkAASYSARLRDVDD-VAFLRALVarlaQEYRVDSQRVYVAGYSNGGQMAFRL 167
Cdd:pfam00326   9 LLADRGYVVAIANgrgsGGYGEaFHD---AGKGDLGQNEFDDfIAAAEYLI----EQGYTDPDRLAIWGGSYGGYLTGAA 81


                  ....*..
gi 15595740   168 AAEAPGL 174
Cdd:pfam00326  82 LNQRPDL 88
COG4188 COG4188
Predicted dienelactone hydrolase [General function prediction only];
64-168 1.08e-03

Predicted dienelactone hydrolase [General function prediction only];


Pssm-ID: 443342 [Multi-domain]  Cd Length: 326  Bit Score: 40.09  E-value: 1.08e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595740  64 SEGAPLLVVLHGSRGDGAQMRRISGYgfdrLAAQeGFLVAYPD----------GFEGHWNDCRKAASYSARLRDV----D 129
Cdd:COG4188  59 GGPFPLVVLSHGLGGSREGYAYLAEH----LASH-GYVVAAPDhpgsnaadlsAALDGLADALDPEELWERPLDLsfvlD 133

                        90       100       110
                ....*....|....*....|....*....|....*....
gi 15595740 130 DVAFLRALVARLAQeyRVDSQRVYVAGYSNGGQMAFRLA 168
Cdd:COG4188 134 QLLALNKSDPPLAG--RLDLDRIGVIGHSLGGYTALALA 170
YbbA COG2819
Predicted hydrolase of the alpha/beta superfamily [General function prediction only];
39-174 3.17e-03

Predicted hydrolase of the alpha/beta superfamily [General function prediction only];


Pssm-ID: 442067 [Multi-domain]  Cd Length: 250  Bit Score: 38.43  E-value: 3.17e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595740  39 GHSEDSSLKVAGLRRHYLLYV--PPG---VSEGAPLLVVLhgsrgDG-AQMRRISGYGfDRLAAQEGFL-------VAYP 105
Cdd:COG2819   5 GQTEYFTLESPILGEDRRIRVylPPGydaPEKRYPVLYML-----DGqNLFDALAGAV-GTLSRLEGGIppaivvgIGNG 78

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15595740 106 DGFEGHWNDC--RKAASYSARLRDVDD-VAFLRALVARL----AQEYRVDSQRVYVAGYSNGGQMAFRLAAEAPGL 174
Cdd:COG2819  79 DDGERRLRDYtpPPAPGYPGPGGPGGGaDAFLRFLEEELkpyiDKRYRTDPERTGLIGHSLGGLFSLYALLKYPDL 154
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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