|
Name |
Accession |
Description |
Interval |
E-value |
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
30-202 |
3.04e-30 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 119.51 E-value: 3.04e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 30 DKGLQSISELSLDSTLHAVNLHCNNISKIEAIDHIWNLQHLDLSSNQISRIEGLNTLTKLCTLNLSCNLITKVEGLEELI 109
Cdd:cd21340 11 DKNITKIDNLSLCKNLKVLYLYDNKITKIENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRISVVEGLENLT 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 110 N------------------------------LTRLNVSYNHIDDLSGLIPLhgikHKLRYIDLHSNRIDSIHHLLQCMVG 159
Cdd:cd21340 91 NleelhienqrlppgekltfdprslaalsnsLRVLNISGNNIDSLEPLAPL----RNLEQLDASNNQISDLEELLDLLSS 166
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 117414162 160 LHFLTNLILEkdgdDNPVCRLPGYRAVILQTLPQLRILDCKNI 202
Cdd:cd21340 167 WPSLRELDLT----GNPVCKKPKYRDKIILASKSLEVLDGKEI 205
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
31-201 |
1.84e-12 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 70.35 E-value: 1.84e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 31 KGLQSISELSLDSTLHAVNLHCNNISKIEAIDHIWNLQHLDLSSNQISRI-EGLNTLTKLCTLNLSCNLITKV-EGLEEL 108
Cdd:COG4886 79 LLLLSLLLLGLTDLGDLTNLTELDLSGNEELSNLTNLESLDLSGNQLTDLpEELANLTNLKELDLSNNQLTDLpEPLGNL 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 109 INLTRLNVSYNHIDDLSGliPLHGIKhKLRYIDLHSNRIDSIHHLLQCMVGLHFLtNLilekdgDDNPVCRLPGyravIL 188
Cdd:COG4886 159 TNLKSLDLSNNQLTDLPE--ELGNLT-NLKELDLSNNQITDLPEPLGNLTNLEEL-DL------SGNQLTDLPE----PL 224
|
170
....*....|...
gi 117414162 189 QTLPQLRILDCKN 201
Cdd:COG4886 225 ANLTNLETLDLSN 237
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
35-227 |
1.43e-10 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 64.57 E-value: 1.43e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 35 SISELSldsTLHAVNLHCNNISKI-EAIDHIWNLQHLDLSSNQISRIEGLNTLTKLCTLNLSCNLITKVEGLEELINLTR 113
Cdd:COG4886 200 PLGNLT---NLEELDLSGNQLTDLpEPLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLTDLPPLANLTNLKT 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 114 LNVSYNHIDDLS-GLIPLHGIKHKLRYIDLHSNRIDSIHHLLQCMVGLHFLTNLILEKDGDDNPVCRLPGYRAVILQTLP 192
Cdd:COG4886 277 LDLSNNQLTDLKlKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLL 356
|
170 180 190
....*....|....*....|....*....|....*
gi 117414162 193 QLRILDCKNIFGEPVNLTEINSSQLQCLEGLLDNL 227
Cdd:COG4886 357 NLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLL 391
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
412-1030 |
1.01e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 62.77 E-value: 1.01e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 412 KVDQSHSEDNTYQSLVEQLDQE-REKRWRAEQAENKLMDYIDELHKHANEKedihslallttDRLKEIIFRERNSKGQLE 490
Cdd:TIGR02168 282 EIEELQKELYALANEISRLEQQkQILRERLANLERQLEELEAQLEELESKL-----------DELAEELAELEEKLEELK 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 491 VMVHKLQNEIKKLTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRLiqEVELKASAADREIYLLRTSLHRE 570
Cdd:TIGR02168 351 EELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERL--EARLERLEDRRERLQQEIEELLK 428
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 571 REQAQQLH----QLLALKEQEHRKELETREFFTDADFQDALAKEIAKEEKKHEQMIKEYQEKIDVLSQQYMDLENEFRIA 646
Cdd:TIGR02168 429 KLEEAELKelqaELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGV 508
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 647 LTVEARRFQ------------DVKDGFENvATELAKSKHA------------LIWAQRKENESS------------SLIK 690
Cdd:TIGR02168 509 KALLKNQSGlsgilgvlseliSVDEGYEA-AIEAALGGRLqavvvenlnaakKAIAFLKQNELGrvtflpldsikgTEIQ 587
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 691 DLTCMVKEQKTKLAEVSKLKQETAANLQNQINTL--EILIEDDKQKSIQIELLKHEKVQLIS---EL-----------AA 754
Cdd:TIGR02168 588 GNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlgGVLVVDDLDNALELAKKLRPGYRIVTldgDLvrpggvitggsAK 667
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 755 KESLIFGLRTERKVWGHELAQQGSSLA---QNRGKLEAQIESLSRENECLRKTNESDSDALRIKCKIIDDQTETIRKLKD 831
Cdd:TIGR02168 668 TNSSILERRREIEELEEKIEELEEKIAeleKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEE 747
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 832 CLQEKDEHIKRLQEKITEIEkctqEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNRKWHDKG 911
Cdd:TIGR02168 748 RIAQLSKELTELEAEIEELE----ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR 823
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 912 ELLCHLETQVKEVKEKFENKEKKLKAERDKSIELQKNaMEKLHSMDDAFKRQVDAIVEAhQAEIAQLANEKQKCIDSANL 991
Cdd:TIGR02168 824 ERLESLERRIAATERRLEDLEEQIEELSEDIESLAAE-IEELEELIEELESELEALLNE-RASLEEALALLRSELEELSE 901
|
650 660 670 680
....*....|....*....|....*....|....*....|..
gi 117414162 992 KVHQIEKEMREL---LEETCKNKKTMEAKIKQLAFALNEIQQ 1030
Cdd:TIGR02168 902 ELRELESKRSELrreLEELREKLAQLELRLEGLEVRIDNLQE 943
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
566-906 |
3.85e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 60.84 E-value: 3.85e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 566 SLHREREQAQQLHqllALKEQEhrKELETREFFTDADFQDALAKEIAKEEKKHEQMIKEYQEKIDVLSQQYMDLENEFRi 645
Cdd:TIGR02168 204 SLERQAEKAERYK---ELKAEL--RELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVS- 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 646 altvearrfqdvkdgfenvatELAKSKHAliwAQRKENESSSLIKDLTCMVKEQKTKLAEVSKLKQETAANLQNQINTLE 725
Cdd:TIGR02168 278 ---------------------ELEEEIEE---LQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLD 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 726 ILIEDDKQKSIQIELLKHEKVQLISELAAKESLIFGLRTERkvwgHELAQQGSSLAQNRGKLEAQIESLsreneclrktn 805
Cdd:TIGR02168 334 ELAEELAELEEKLEELKEELESLEAELEELEAELEELESRL----EELEEQLETLRSKVAQLELQIASL----------- 398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 806 esdsdalrikckiiddqTETIRKLKDCLQEKDEHIKRLQEKITEIEKCTQEQldekssQLDEVLEKLERHNERKEKLKQQ 885
Cdd:TIGR02168 399 -----------------NNEIERLEARLERLEDRRERLQQEIEELLKKLEEA------ELKELQAELEELEEELEELQEE 455
|
330 340
....*....|....*....|.
gi 117414162 886 LKGKEVELEEIRKAYSTLNRK 906
Cdd:TIGR02168 456 LERLEEALEELREELEEAEQA 476
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
509-903 |
1.57e-08 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 58.98 E-value: 1.57e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 509 KAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRLIQEVELKASAADREIYLLRTSLHREREQA----QQLHQLLA-- 582
Cdd:pfam15921 307 QARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESgnldDQLQKLLAdl 386
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 583 -LKEQEHRKELETREFFTDADFQ-----DALAKEIAK---EEKKHEQMIKEYQEKIDVLSQQYMDL---ENEFRIALTVE 650
Cdd:pfam15921 387 hKREKELSLEKEQNKRLWDRDTGnsitiDHLRRELDDrnmEVQRLEALLKAMKSECQGQMERQMAAiqgKNESLEKVSSL 466
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 651 ARRFQDVKDGFENVATELAKSKHALIWAQRKenessslIKDLTCMVKEQKTKL----AEVSKLKQETAANLQnQINTLEi 726
Cdd:pfam15921 467 TAQLESTKEMLRKVVEELTAKKMTLESSERT-------VSDLTASLQEKERAIeatnAEITKLRSRVDLKLQ-ELQHLK- 537
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 727 lIEDDKQKSIQIELlkhEKVQLisELAAKESLIFGLRTERKVWGHELAQQG---SSLAQNRGKLEAQIESLSRE------ 797
Cdd:pfam15921 538 -NEGDHLRNVQTEC---EALKL--QMAEKDKVIEILRQQIENMTQLVGQHGrtaGAMQVEKAQLEKEINDRRLElqefki 611
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 798 -----NECLRKTNESDSDALRIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEKCTQEQldekssqldEVLE-- 870
Cdd:pfam15921 612 lkdkkDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDY---------EVLKrn 682
|
410 420 430
....*....|....*....|....*....|....*.
gi 117414162 871 ---KLERHNERKEKLKQQLKGKEVELEEIRKAYSTL 903
Cdd:pfam15921 683 frnKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSM 718
|
|
| LRR_9 |
pfam14580 |
Leucine-rich repeat; |
70-202 |
4.15e-08 |
|
Leucine-rich repeat;
Pssm-ID: 405295 [Multi-domain] Cd Length: 175 Bit Score: 54.00 E-value: 4.15e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 70 LDLSSNQISRIEGLNTLTKLCTLNLSCNLITKV-EGLEELI-NLTRLNVSYNHIDDLSGLIPLHGIKhKLRYIDLHsnri 147
Cdd:pfam14580 47 IDFSDNEIRKLDGFPLLRRLKTLLLNNNRICRIgEGLGEALpNLTELILTNNNLQELGDLDPLASLK-KLTFLSLL---- 121
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 117414162 148 dsihhllqcmvglhfltnlilekdgdDNPVCRLPGYRAVILQTLPQLRILDCKNI 202
Cdd:pfam14580 122 --------------------------RNPVTNKPHYRLYVIYKVPQLRLLDFRKV 150
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
521-899 |
6.01e-08 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 56.87 E-value: 6.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 521 LRTLEKTLEkmerqkrqqqaaqirliqevelkasaadreiyllrtSLHREREQAQQLHQLlalkeQEHRKELETREFFTD 600
Cdd:COG1196 195 LGELERQLE------------------------------------PLERQAEKAERYREL-----KEELKELEAELLLLK 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 601 ADFQDALAKEIAKEEKKHEQMIKEYQEKIDVLSQQYmdleNEFRIALTVEARRFQDVKDGFENVATELAKSKHALIWAQR 680
Cdd:COG1196 234 LRELEAELEELEAELEELEAELEELEAELAELEAEL----EELRLELEELELELEEAQAEEYELLAELARLEQDIARLEE 309
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 681 KENESSSLIKDLtcmvKEQKTKLAEVSKLKQETAANLQNQINTLEILIEDDKQksiQIELLKHEKVQLISELAAKESLIF 760
Cdd:COG1196 310 RRRELEERLEEL----EEELAELEEELEELEEELEELEEELEEAEEELEEAEA---ELAEAEEALLEAEAELAEAEEELE 382
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 761 GLRTERKvwghELAQQGSSLAQNRGKLEAQIESLSRENECLRKTNESDSDALRIKCKIIDDQTETIRKLKDCLQEKDEHI 840
Cdd:COG1196 383 ELAEELL----EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEE 458
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 117414162 841 KRLQEKITEiekcTQEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKA 899
Cdd:COG1196 459 EALLELLAE----LLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAA 513
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
428-897 |
1.08e-07 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 56.20 E-value: 1.08e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 428 EQLDQEREKRWRAEQAE-----NKLMDYIDELHKHANEKEDIHSLALLTTDRLKEIIFRERNSKGQLEVmvhkLQNEIKK 502
Cdd:PRK02224 187 GSLDQLKAQIEEKEEKDlherlNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELET----LEAEIED 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 503 LTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQqqaaqirLIQEVELKaSAADREIYLLRTSLHREREQAQQLHQLLA 582
Cdd:PRK02224 263 LRETIAETEREREELAEEVRDLRERLEELEEERDD-------LLAEAGLD-DADAEAVEARREELEDRDEELRDRLEECR 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 583 LKEQEHRKELET-REfftDADFQDALAKEIAKEEKKHEQMIKEYQEKIDVLSQQYMDLENEFRialTVEARrFQDVKDGF 661
Cdd:PRK02224 335 VAAQAHNEEAESlRE---DADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIE---ELRER-FGDAPVDL 407
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 662 ENVATELAKSKHALIWAQRKENESSSLIKDLTCMVKEQKTKLAEvSKLKQ-----------ETAANLQNQINTLEILIED 730
Cdd:PRK02224 408 GNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEA-GKCPEcgqpvegsphvETIEEDRERVEELEAELED 486
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 731 DKQKSIQIEllkhEKVQLISELAAKESLIFGLRTERKVWGHELAQQGSSLAQNRGKLE------AQIESLSRENECLRKT 804
Cdd:PRK02224 487 LEEEVEEVE----ERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEelreraAELEAEAEEKREAAAE 562
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 805 NESDSDALRIKCKIID----------DQTETIRKLKDCLQEKDEHIKRLQEK---ITEIEKCTQEQLDEKSSQ------- 864
Cdd:PRK02224 563 AEEEAEEAREEVAELNsklaelkeriESLERIRTLLAAIADAEDEIERLREKreaLAELNDERRERLAEKRERkreleae 642
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|..
gi 117414162 865 -------------------LDEVLEKLERHNERKEKLKQQLKGKEVELEEIR 897
Cdd:PRK02224 643 fdearieearedkeraeeyLEQVEEKLDELREERDDLQAEIGAVENELEELE 694
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
478-874 |
1.11e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 56.22 E-value: 1.11e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 478 IIFRERNSKgQLEVMVHKLQNEIKKLTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRLIQEVELKASAAD 557
Cdd:TIGR02168 672 ILERRREIE-ELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA 750
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 558 ReiyllrtsLHREREQAQQLHQLLALKEQEHRKELetrefftdadfqdalaKEIAKEEKKHEQMIKEYQEKIDVLSQQYM 637
Cdd:TIGR02168 751 Q--------LSKELTELEAEIEELEERLEEAEEEL----------------AEAEAEIEELEAQIEQLKEELKALREALD 806
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 638 DLENEfriaLTVEARRFQDVKDGFENVATELAkskhaliwaqrkenessslikdltcMVKEQKTKLAEVSKLKQETAANL 717
Cdd:TIGR02168 807 ELRAE----LTLLNEEAANLRERLESLERRIA-------------------------ATERRLEDLEEQIEELSEDIESL 857
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 718 QNQINTLEILIEddkQKSIQIELLKHEKVQLISELAAKESLIFGLRTERKVWG---HELAQQGSSLAQNRGKLEAQIESL 794
Cdd:TIGR02168 858 AAEIEELEELIE---ELESELEALLNERASLEEALALLRSELEELSEELRELEskrSELRRELEELREKLAQLELRLEGL 934
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 795 -SRENECLRKTNESDSDALrikckiiDDQTETIRKLKDCLQEKDEHIKRLQEKITEI-------------EKCTQEQLDE 860
Cdd:TIGR02168 935 eVRIDNLQERLSEEYSLTL-------EEAEALENKIEDDEEEARRRLKRLENKIKELgpvnlaaieeyeeLKERYDFLTA 1007
|
410
....*....|....
gi 117414162 861 KSSQLDEVLEKLER 874
Cdd:TIGR02168 1008 QKEDLTEAKETLEE 1021
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
431-1027 |
1.37e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 55.84 E-value: 1.37e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 431 DQEREKRWRAEQAENKLMDYIDELHKHANEKEDihslallttdrLKEIIFRERNSKGQLEVMVHKLQNEIKKLTVELmka 510
Cdd:TIGR02169 308 RSIAEKERELEDAEERLAKLEAEIDKLLAEIEE-----------LEREIEEERKRRDKLTEEYAELKEELEDLRAEL--- 373
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 511 kdqQEDHLKHLRTLEKTlekmerqkrqqqaaqirliQEVELKASAADREIYLLRTSLHREREQAQQLHQLLA-LKEQEHR 589
Cdd:TIGR02169 374 ---EEVDKEFAETRDEL-------------------KDYREKLEKLKREINELKRELDRLQEELQRLSEELAdLNAAIAG 431
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 590 KELETREFftdadfqDALAKEIAKEEKKHEQMIKEYQEKIDVLSQQYMDLENEFRialtvearrfqDVKDGFENVATELA 669
Cdd:TIGR02169 432 IEAKINEL-------EEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYD-----------RVEKELSKLQRELA 493
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 670 KSKHALIWAQRKENESSSLIKDLTCMVKEQKTKLAEVSKLKQETAANLQ----NQINTleILIEDDKQKSIQIELLKHEK 745
Cdd:TIGR02169 494 EAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEvaagNRLNN--VVVEDDAVAKEAIELLKRRK 571
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 746 ------------------VQLISELAAKESLIFGLRTERK-------VWGHELAQQGSSLAQnrgKLEAQIESLSRENEC 800
Cdd:TIGR02169 572 agratflplnkmrderrdLSILSEDGVIGFAVDLVEFDPKyepafkyVFGDTLVVEDIEAAR---RLMGKYRMVTLEGEL 648
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 801 L------------RKTNESDSDALRIKCKIIDDQTETIRKLKDCLQEKDEHIK-RLQEKITEIEKCTQEqLDEKSSQLDE 867
Cdd:TIGR02169 649 FeksgamtggsraPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIEnRLDELSQELSDASRK-IGEIEKEIEQ 727
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 868 VLEKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKFENkekklkaERDKSIELQK 947
Cdd:TIGR02169 728 LEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH-------SRIPEIQAEL 800
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 948 NAMEKLHSMDDAFKRQVDAIVEAHQAEIAQLANEKQKCIDSANLKVHQIeKEMRELLEETCKNKKTMEAKIKQLAFALNE 1027
Cdd:TIGR02169 801 SKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQI-KSIEKEIENLNGKKEELEEELEELEAALRD 879
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
550-886 |
2.67e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 55.06 E-value: 2.67e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 550 ELKASAADREIYLLRTSLHREREQAQQLHQLLALKEQEHrkeletrefftdadfqDALAKEIAKEEKKHEQMIKEYQEki 629
Cdd:TIGR02168 217 ELKAELRELELALLVLRLEELREELEELQEELKEAEEEL----------------EELTAELQELEEKLEELRLEVSE-- 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 630 dvlsqqymdLENEFRIaltvearrfqdvkdgfenvatelakskhaliwAQRKENESSSLIKDLTCMVKEQKTKLAEVSKL 709
Cdd:TIGR02168 279 ---------LEEEIEE--------------------------------LQKELYALANEISRLEQQKQILRERLANLERQ 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 710 KQETAANLQNQINTLEILIEDDKQKSIQIELLKHEKVQLISELAAKESLIF----GLRTERKVWG------HELAQQGSS 779
Cdd:TIGR02168 318 LEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEelesRLEELEEQLEtlrskvAQLELQIAS 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 780 LAQNRGKLEAQIESLSRENECLRKTNESDSDAL-RIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKIteiekctQEQL 858
Cdd:TIGR02168 398 LNNEIERLEARLERLEDRRERLQQEIEELLKKLeEAELKELQAELEELEEELEELQEELERLEEALEEL-------REEL 470
|
330 340
....*....|....*....|....*...
gi 117414162 859 DEKSSQLDEVLEKLERHNERKEKLKQQL 886
Cdd:TIGR02168 471 EEAEQALDAAERELAQLQARLDSLERLQ 498
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
441-1011 |
3.16e-07 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 54.74 E-value: 3.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 441 EQAENKLMDY---IDELHKHANEKEDIHS----------------LALLTTDRLKEIIFRERNSKGQlevmvHKLQNEIK 501
Cdd:pfam15921 74 EHIERVLEEYshqVKDLQRRLNESNELHEkqkfylrqsvidlqtkLQEMQMERDAMADIRRRESQSQ-----EDLRNQLQ 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 502 KLTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRLIQEVElkaSAADREIYllrtslhrEREQAQQLH-QL 580
Cdd:pfam15921 149 NTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFE---EASGKKIY--------EHDSMSTMHfRS 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 581 LALKEQEHRKELETREFFtdadfqdaLAKEIAKEEKKHEQMIKEYQEKIDVLSQQYMDL------ENEFRI-ALTVEARR 653
Cdd:pfam15921 218 LGSAISKILRELDTEISY--------LKGRIFPVEDQLEALKSESQNKIELLLQQHQDRieqlisEHEVEItGLTEKASS 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 654 FQDVKDGFEN---VATELAKSKHALIWAQRKENESS--------------------SLIKDLTCMVKEQKTKLAEVSKLK 710
Cdd:pfam15921 290 ARSQANSIQSqleIIQEQARNQNSMYMRQLSDLESTvsqlrselreakrmyedkieELEKQLVLANSELTEARTERDQFS 369
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 711 QETaANLQNQintLEILIEDDKQKSIQIELLKHEKVQLISELAAKESLIFGLRTERKVWGHELAQQGSSL----AQNRGK 786
Cdd:pfam15921 370 QES-GNLDDQ---LQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLkamkSECQGQ 445
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 787 LEAQIESLSRENECLRKTN------ESDSDALR-------IKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEKC 853
Cdd:pfam15921 446 MERQMAAIQGKNESLEKVSsltaqlESTKEMLRkvveeltAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSR 525
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 854 TQEQLDEkSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLnrkwhdkgellchleTQVKEVKEKFENKEK 933
Cdd:pfam15921 526 VDLKLQE-LQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENM---------------TQLVGQHGRTAGAMQ 589
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 934 KLKAERDKSIELQKNAMEKLHSMDDafkrQVDAIVEAHQAEIAQLANEKQKCIDSANLK---VHQIEKEMRELLEE--TC 1008
Cdd:pfam15921 590 VEKAQLEKEINDRRLELQEFKILKD----KKDAKIRELEARVSDLELEKVKLVNAGSERlraVKDIKQERDQLLNEvkTS 665
|
...
gi 117414162 1009 KNK 1011
Cdd:pfam15921 666 RNE 668
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
704-1030 |
3.72e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 54.29 E-value: 3.72e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 704 AEVSKLKQ----------ETAANLQnQINtlEILIEDDKQ-KSIQIELLKHEKVQ-LISELAAKESLIFGLRTERKVWG- 770
Cdd:TIGR02168 165 AGISKYKErrketerkleRTRENLD-RLE--DILNELERQlKSLERQAEKAERYKeLKAELRELELALLVLRLEELREEl 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 771 HELAQQGSSLAQNRGKLEAQIESLSRENECLRKTNESDSDALRIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEI 850
Cdd:TIGR02168 242 EELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEEL 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 851 EkctqEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKFEN 930
Cdd:TIGR02168 322 E----AQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIAS 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 931 KEKKLKAERDKSIELQKNAMEKLHSMDDAFKRQVDAIVEAHQAEIA---QLANEKQKCIDSANLKVHQIEKEMRELLEET 1007
Cdd:TIGR02168 398 LNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEeleEELEELQEELERLEEALEELREELEEAEQAL 477
|
330 340
....*....|....*....|...
gi 117414162 1008 CKNKKTmEAKIKQLAFALNEIQQ 1030
Cdd:TIGR02168 478 DAAERE-LAQLQARLDSLERLQE 499
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
423-1030 |
4.45e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 54.29 E-value: 4.45e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 423 YQSLVEQLDQEREKRWRAEQAENKLMDYIDELHKHANEKEDIHSLALLTTDRLKEIIFRERNSKGQLEVMVHKLQNEIKK 502
Cdd:TIGR02168 234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAN 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 503 LTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAqirlIQEVELKASAADREIYLLRTSLHREREQAQQLHQLLA 582
Cdd:TIGR02168 314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEE----LESLEAELEELEAELEELESRLEELEEQLETLRSKVA 389
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 583 LKEQE---HRKELET-REFFTD-ADFQDALAKEIAKEEKK-HEQMIKEYQEKIDVLSQQYMDLENEFRialTVEARrfqd 656
Cdd:TIGR02168 390 QLELQiasLNNEIERlEARLERlEDRRERLQQEIEELLKKlEEAELKELQAELEELEEELEELQEELE---RLEEA---- 462
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 657 vkdgFENVATELAKSKHALIWAQRKENESSSLIKDLTCMVKEQKTKLAEVSKLKQEtAANLQNQINTLEILIEDDKQKSI 736
Cdd:TIGR02168 463 ----LEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKN-QSGLSGILGVLSELISVDEGYEA 537
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 737 QIELLKHEKVQ--LISELAAKESLIFGLRTERKVWGHELAQQGSSLAQNRGKLEaqiESLSRENECLRKTNESDSDALRI 814
Cdd:TIGR02168 538 AIEAALGGRLQavVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDR---EILKNIEGFLGVAKDLVKFDPKL 614
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 815 K---------CKIIDDQTETIRKLKDCLQE-----KDEHIKRLQEKITEIEKCTQEQLDEKSSQLDEVLEKLERHNERKE 880
Cdd:TIGR02168 615 RkalsyllggVLVVDDLDNALELAKKLRPGyrivtLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIA 694
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 881 KLKQQLKGKEVELEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKFENKEKKLKAERDKSIELQKNAM---EKLHSMD 957
Cdd:TIGR02168 695 ELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEeleERLEEAE 774
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 117414162 958 DAFKRQVDAIVEAhQAEIAQLANEKQ---KCIDSANLKVHQIEKEMRELLEETCKNKKTMEAKIKQLAFALNEIQQ 1030
Cdd:TIGR02168 775 EELAEAEAEIEEL-EAQIEQLKEELKalrEALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEE 849
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
545-897 |
4.92e-07 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 53.75 E-value: 4.92e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 545 LIQEVElkasAADREIYLLRTSLHREREQAQQLHQLLALKEQEHRKEL-ETREFFTD--------ADFQDALAKE---IA 612
Cdd:pfam07888 46 LLQAQE----AANRQREKEKERYKRDREQWERQRRELESRVAELKEELrQSREKHEEleekykelSASSEELSEEkdaLL 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 613 KEEKKHEQMIKEYQEKIDVLSQQYMDLENEFRialtveaRRFQDVKDGFENVATELAKSKHALIWAQRKENESSSLIKDL 692
Cdd:pfam07888 122 AQRAAHEARIRELEEDIKTLTQRVLERETELE-------RMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEF 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 693 tcmvKEQKTKLAEvsklKQETAANLQNQINTLEILIEDDKQKSIQIELLKHEKVQLISELAAKESLIFGLRTERKVWGH- 771
Cdd:pfam07888 195 ----QELRNSLAQ----RDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAAq 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 772 -------------ELAQQGSSLAQNRGKLEAQIESLSRENECLRKTNESDSDalrikckiiddqteTIRKLKDCLQEKDE 838
Cdd:pfam07888 267 rdrtqaelhqarlQAAQLTLQLADASLALREGRARWAQERETLQQSAEADKD--------------RIEKLSAELQRLEE 332
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 117414162 839 hikRLQEKITEIEKCTQEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIR 897
Cdd:pfam07888 333 ---RLQEERMEREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEKQ 388
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
419-1007 |
8.95e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 53.02 E-value: 8.95e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 419 EDNTYQSLVEQLDQEREKRWRAEQAENKLMDYIDELHKHANEKEDIHSLALLTTDRLKEIIFRERNSKGQLEVMVHKLQN 498
Cdd:COG1196 244 LEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEE 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 499 EIKKLTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRLIQEVELKASAADREIYLLRTSLHREREQAQQLH 578
Cdd:COG1196 324 ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 579 QLLALKEQEHRKELETREFFTDADFQDALAKEIAKEEKKHEQMIKEYQEKIDVLSQQyMDLENEFRIALTVEARRFQDVK 658
Cdd:COG1196 404 ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEA-LLELLAELLEEAALLEAALAEL 482
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 659 DGFENVATELAKSKHALIWAQRKENESSSLIKDLTCMVKEQKTKLAEVS-KLKQETAANLQNQINTLEILIEDDKQKSIQ 737
Cdd:COG1196 483 LEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGvEAAYEAALEAALAAALQNIVVEDDEVAAAA 562
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 738 IELLKHEK--------VQLISELAAKESLIFGLRTERKVWGHE-LAQQGSSLAQNRGKLEAQIESLSRENECLRKTNESD 808
Cdd:COG1196 563 IEYLKAAKagratflpLDKIRARAALAAALARGAIGAAVDLVAsDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTL 642
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 809 SDALRIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEKCTQEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKG 888
Cdd:COG1196 643 AGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELE 722
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 889 KEVELEEIRKAYSTLNRKWHDKGELLchletqvkevkekfeNKEKKLKAERDKSIELQKNAMEKLhsmddafKRQVD--- 965
Cdd:COG1196 723 EEALEEQLEAEREELLEELLEEEELL---------------EEEALEELPEPPDLEELERELERL-------EREIEalg 780
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*.
gi 117414162 966 -----AIVEAHQAE---------IAQLANEKQKcIDSAnlkVHQIEKEMRELLEET 1007
Cdd:COG1196 781 pvnllAIEEYEELEerydflseqREDLEEARET-LEEA---IEEIDRETRERFLET 832
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
609-1020 |
1.35e-06 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 52.33 E-value: 1.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 609 KEIAKEEKKHEQMIKEYQEKIDVLSQQYMDLENEfriaLTVEARRFQDVKDGFENVATELAKSKHALIwaqRKENESSSL 688
Cdd:TIGR04523 57 KNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDK----LKKNKDKINKLNSDLSKINSEIKNDKEQKN---KLEVELNKL 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 689 IKDLTCMVKEQKTKLAEVSKLKQEtAANLQNQINTLEILIEDdkqksiqielLKHEKVQLISELAAKESLIFGLRTERKV 768
Cdd:TIGR04523 130 EKQKKENKKNIDKFLTEIKKKEKE-LEKLNNKYNDLKKQKEE----------LENELNLLEKEKLNIQKNIDKIKNKLLK 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 769 WGHELAQQGSSLAQNRgKLEAQIESLSRENECLRKTNESDSDALRIKCKIIDdqtETIRKLKDCLQEKDEHIKRLQEKIT 848
Cdd:TIGR04523 199 LELLLSNLKKKIQKNK-SLESQISELKKQNNQLKDNIEKKQQEINEKTTEIS---NTQTQLNQLKDEQNKIKKQLSEKQK 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 849 EIEKcTQEQLDEKSSQLDEVLEKLERHNERKE-----KLKQQLKGKEVELEEIRKAYSTLNRKWHDKGELLCHLETQVKE 923
Cdd:TIGR04523 275 ELEQ-NNKKIKELEKQLNQLKSEISDLNNQKEqdwnkELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTN 353
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 924 VKEKFEnkekklkaERDKSIELQKNAMEKLHSMDDAFKRQVD------AIVEAHQAEIAQLANEKQKCIDSANLKVHQIE 997
Cdd:TIGR04523 354 SESENS--------EKQRELEEKQNEIEKLKKENQSYKQEIKnlesqiNDLESKIQNQEKLNQQKDEQIKKLQQEKELLE 425
|
410 420
....*....|....*....|...
gi 117414162 998 KEMRELLEETCKNKKTMEAKIKQ 1020
Cdd:TIGR04523 426 KEIERLKETIIKNNSEIKDLTNQ 448
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
427-909 |
1.46e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 52.61 E-value: 1.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 427 VEQLDQEREKRWRAEQAENKLmDYIDELHKHANEKEDIHSLALLTT--DRLKEIIFRERNSKGQLEVMVHKLQNEIKKLT 504
Cdd:COG4913 251 IELLEPIRELAERYAAARERL-AELEYLRAALRLWFAQRRLELLEAelEELRAELARLEAELERLEARLDALREELDELE 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 505 VELMKAKDQQEDHLKH-LRTLEKTLEKMERQKRQQQAAQIRLiqEVELKASAAD-----REIYLLRTSLHREREQAQQLH 578
Cdd:COG4913 330 AQIRGNGGDRLEQLEReIERLERELEERERRRARLEALLAAL--GLPLPASAEEfaalrAEAAALLEALEEELEALEEAL 407
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 579 QLLALKEQEHRKELetrefftdadfqDALAKEIAKEEKKHEQMIKEYQEKIDVLSQQ-------------YMDLENE--- 642
Cdd:COG4913 408 AEAEAALRDLRREL------------RELEAEIASLERRKSNIPARLLALRDALAEAlgldeaelpfvgeLIEVRPEeer 475
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 643 -----------FRIALTVEARRFQDVKDGFENVATELA----KSKHALIWAQRKENESSSLIKDLTcmVKEQ------KT 701
Cdd:COG4913 476 wrgaiervlggFALTLLVPPEHYAAALRWVNRLHLRGRlvyeRVRTGLPDPERPRLDPDSLAGKLD--FKPHpfrawlEA 553
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 702 KLAEVSKLKQ-ETAANLQN---------QINTLEILIEDDKQKSI------------QIELLKHEKVQLISELAAKESLI 759
Cdd:COG4913 554 ELGRRFDYVCvDSPEELRRhpraitragQVKGNGTRHEKDDRRRIrsryvlgfdnraKLAALEAELAELEEELAEAEERL 633
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 760 FGLRTERKvwghELAQQGSSLAQ---------NRGKLEAQIESLSRENECLRKTN-------------ESDSDALRikcK 817
Cdd:COG4913 634 EALEAELD----ALQERREALQRlaeyswdeiDVASAEREIAELEAELERLDASSddlaaleeqleelEAELEELE---E 706
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 818 IIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEKC----TQEQLDEKSSQL--DEVLEKLERH-NERKEKLKQQLKGKE 890
Cdd:COG4913 707 ELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLarleLRALLEERFAAAlgDAVERELRENlEERIDALRARLNRAE 786
|
570
....*....|....*....
gi 117414162 891 VELEEIRKAYstlNRKWHD 909
Cdd:COG4913 787 EELERAMRAF---NREWPA 802
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
494-1032 |
3.46e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 51.21 E-value: 3.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 494 HKLQNEIKKLTVELmkAKDQQEDHLKHLRTLEKTLEKMERQKRQQQaaqiRLIQEVELKASAADREIYLLRTSLHREREQ 573
Cdd:TIGR02168 216 KELKAELRELELAL--LVLRLEELREELEELQEELKEAEEELEELT----AELQELEEKLEELRLEVSELEEEIEELQKE 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 574 AQQLHQLLALKEQ------EHRKELETREFFTDADFQDALAKEIAKEEKKHEQmikeyQEKIDVLSQQYMDLEN---EFR 644
Cdd:TIGR02168 290 LYALANEISRLEQqkqilrERLANLERQLEELEAQLEELESKLDELAEELAEL-----EEKLEELKEELESLEAeleELE 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 645 IALTVEARRFQDVKDGFENVATELAKSKH--ALIWAQRKENEssSLIKDLTCMVKEQKTKLAEVSKLKQETAAN-LQNQI 721
Cdd:TIGR02168 365 AELEELESRLEELEEQLETLRSKVAQLELqiASLNNEIERLE--ARLERLEDRRERLQQEIEELLKKLEEAELKeLQAEL 442
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 722 NTLEILIED-----------DKQKSIQIELLKHEKVQLISELAAKESLIFGL-----------RTERKVWGHELAQQG-- 777
Cdd:TIGR02168 443 EELEEELEElqeelerleeaLEELREELEEAEQALDAAERELAQLQARLDSLerlqenlegfsEGVKALLKNQSGLSGil 522
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 778 ----------------------------------------SSLAQNR-GKL--------------EAQIESLSRENECLR 802
Cdd:TIGR02168 523 gvlselisvdegyeaaieaalggrlqavvvenlnaakkaiAFLKQNElGRVtflpldsikgteiqGNDREILKNIEGFLG 602
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 803 KTNESDSDALRIK---------CKIIDDQTETIRKLKD------------------------------CLQEKDEHIKRL 843
Cdd:TIGR02168 603 VAKDLVKFDPKLRkalsyllggVLVVDDLDNALELAKKlrpgyrivtldgdlvrpggvitggsaktnsSILERRREIEEL 682
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 844 QEKITEIEkctqEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNRKWHDKGELLCHLETQVKE 923
Cdd:TIGR02168 683 EEKIEELE----EKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE 758
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 924 VKEKFENKEKKLKAERDKSIELQKNaMEKLHSMDDAFKRQVDAIVEAHQAEIAQLANEKQKcIDSANLKVHQIEKEMREL 1003
Cdd:TIGR02168 759 LEAEIEELEERLEEAEEELAEAEAE-IEELEAQIEQLKEELKALREALDELRAELTLLNEE-AANLRERLESLERRIAAT 836
|
650 660 670
....*....|....*....|....*....|..
gi 117414162 1004 ---LEETCKNKKTMEAKIKQLAFALNEIQQDM 1032
Cdd:TIGR02168 837 errLEDLEEQIEELSEDIESLAAEIEELEELI 868
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
427-1032 |
3.82e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 51.09 E-value: 3.82e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 427 VEQLDQEREK--RWRAEQAENKLMD---YIDELHKHANEKEDIHSLALLTTDRLKEIIFRERNSKGQLEvmvhKLQNEIK 501
Cdd:COG1196 202 LEPLERQAEKaeRYRELKEELKELEaelLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELE----ELRLELE 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 502 KLTVELmkaKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRLIQEVELKASAADREIYLLRTSLHREREQAQQLHQLL 581
Cdd:COG1196 278 ELELEL---EEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELE 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 582 ALKEQEHRKELETREFFTDADFQDALAKEIAKEEKKHEQMIKEYQEKIDVLSQQYMDLENEFRIALTVEARRFQDVKDGF 661
Cdd:COG1196 355 EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELE 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 662 ENVATELAKSKHALIWAQRKENESSSLIKDLTCMVKEQKTKLAEVSKLKQEtAANLQNQINTLEILIEDDKQKSIQIELL 741
Cdd:COG1196 435 EEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE-LAEAAARLLLLLEAEADYEGFLEGVKAA 513
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 742 KHEKVQLISELAAKESLIFGLRTERKVWGHELAQQGSSLAQNRGKLEAQIESLSRENEcLRKTNESdsdalrikckiidd 821
Cdd:COG1196 514 LLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKA-GRATFLP-------------- 578
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 822 qtetIRKLKDCLQEKDEHIKRLQEKITEIEKCTQEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYS 901
Cdd:COG1196 579 ----LDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGE 654
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 902 TLNRKwhdkgellcHLETQVKEVKEKFENKEKKLKAERDKSIELQKNAMEKLHSMDDAFKRQVDAIVEAHQAEIAQLANE 981
Cdd:COG1196 655 GGSAG---------GSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEA 725
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|.
gi 117414162 982 KQKCIDSANLKVHQIEKEMRELLEETCKNKKTMEAKIKQLAFALNEIQQDM 1032
Cdd:COG1196 726 LEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
697-899 |
4.74e-06 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 50.21 E-value: 4.74e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 697 KEQKTKLAEVSKLKQETAANLQNQINTLEILIEDDKQKSIQIELLKHEKVQLISELAAKESLIFGLRTERKVWGHELAQQ 776
Cdd:COG3883 19 QAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRS 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 777 GSSLaqnrGKLEAQIESlsreneclrktnESDSDAL-RIK--CKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEKC 853
Cdd:COG3883 99 GGSV----SYLDVLLGS------------ESFSDFLdRLSalSKIADADADLLEELKADKAELEAKKAELEAKLAELEAL 162
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 117414162 854 TQEQLDEKS---SQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKA 899
Cdd:COG3883 163 KAELEAAKAeleAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAA 211
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
66-107 |
9.42e-06 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 43.39 E-value: 9.42e-06
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 117414162 66 NLQHLDLSSNQISRIEGLNTLTKLCTLNLS-CNLITKVEGLEE 107
Cdd:pfam12799 2 NLEVLDLSNNQITDIPPLAKLPNLETLDLSgNNKITDLSDLAN 44
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
837-1031 |
1.04e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 49.06 E-value: 1.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 837 DEHIKRLQEKITEIekctQEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNRKWHDKGELLch 916
Cdd:COG3883 15 DPQIQAKQKELSEL----QAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREEL-- 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 917 letqvkevkekfenkekklkAERDKSIELQKNAMEKL------HSMDDAFKRQ--VDAIVEAHQAEIAQLANEKQKcIDS 988
Cdd:COG3883 89 --------------------GERARALYRSGGSVSYLdvllgsESFSDFLDRLsaLSKIADADADLLEELKADKAE-LEA 147
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 117414162 989 ANLKVHQIEKEMRELLEETCKNKKTMEAKIKQLAFALNEIQQD 1031
Cdd:COG3883 148 KKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAE 190
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
474-1024 |
1.13e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 49.68 E-value: 1.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 474 RLKEIIFRERNSKGQLEvMVHKLQNEIKKLTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRLIQEV-ELK 552
Cdd:PRK03918 208 EINEISSELPELREELE-KLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVkELK 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 553 ASAADREIYLLRTSLHREREQAQQLHQLLALKEQEHRKELEtrefftdadfqdalaKEIAKEEKKHEQmIKEYQEKIDVL 632
Cdd:PRK03918 287 ELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIE---------------ERIKELEEKEER-LEELKKKLKEL 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 633 SQQYMDLENEFRI-----ALTVEARRFQDVKDGF--ENVATELAKSKHALIWAQRKENESSSLIKDLTCMVKEQKTKLAE 705
Cdd:PRK03918 351 EKRLEELEERHELyeeakAKKEELERLKKRLTGLtpEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEE 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 706 VSKLK-----------QETAANLQNQInTLEIL-IEDDKQKSI-QIELLKHEKVQLISELAaKESLIFGLRterkvwghE 772
Cdd:PRK03918 431 LKKAKgkcpvcgreltEEHRKELLEEY-TAELKrIEKELKEIEeKERKLRKELRELEKVLK-KESELIKLK--------E 500
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 773 LAQQGSSLAQNRGKLEaqIESLSRENECLRKTNEsDSDALRIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEK 852
Cdd:PRK03918 501 LAEQLKELEEKLKKYN--LEELEKKAEEYEKLKE-KLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLK 577
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 853 CTQEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNrkwhDKGELLCHLETQVKEVKEKFENKE 932
Cdd:PRK03918 578 ELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELD----KAFEELAETEKRLEELRKELEELE 653
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 933 KKLKAERDKSIELQKNAMEKLHSMDDAFKRQVDAIVEAHQAEIAQLANEKQKcIDSANLKVHQIEKeMRELLEETCKNKK 1012
Cdd:PRK03918 654 KKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEE-REKAKKELEKLEK-ALERVEELREKVK 731
|
570
....*....|..
gi 117414162 1013 TMEAKIKQLAFA 1024
Cdd:PRK03918 732 KYKALLKERALS 743
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
786-1004 |
1.36e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 49.53 E-value: 1.36e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 786 KLEAQIESLSRenecLRKTNEsDSDALRIKCKIIDD---------QTETIRKLKDCLQEKDEHIKRLQEKITEIEkctqE 856
Cdd:COG4913 246 DAREQIELLEP----IRELAE-RYAAARERLAELEYlraalrlwfAQRRLELLEAELEELRAELARLEAELERLE----A 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 857 QLDEKSSQLDEVLEKLERH-NERKEKLKQQLKGKEVELEEIRKAYSTLNrkwhdkgELLCHLETQVKEVKEKFENKEKKL 935
Cdd:COG4913 317 RLDALREELDELEAQIRGNgGDRLEQLEREIERLERELEERERRRARLE-------ALLAALGLPLPASAEEFAALRAEA 389
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 117414162 936 KAERDKSIELQKNAMEKLHSMDDAFKRQVDAIvEAHQAEIAQLANeKQKCIDSanlKVHQIEKEMRELL 1004
Cdd:COG4913 390 AALLEALEEELEALEEALAEAEAALRDLRREL-RELEAEIASLER-RKSNIPA---RLLALRDALAEAL 453
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
546-921 |
1.67e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 48.91 E-value: 1.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 546 IQEVELKASAADREIYLLRTSLHR---EREQAQQLHQLLALKEQEHRKELETREFFTDADFQ------DALAKEIAKEEK 616
Cdd:TIGR02169 179 LEEVEENIERLDLIIDEKRQQLERlrrEREKAERYQALLKEKREYEGYELLKEKEALERQKEaierqlASLEEELEKLTE 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 617 KHEQMIKEYQEKIDVLSQ---QYMDLENEfrialtvEARRFQdvkdgfenvaTELAKSKHALIWAQRKENESSSLIKDLt 693
Cdd:TIGR02169 259 EISELEKRLEEIEQLLEElnkKIKDLGEE-------EQLRVK----------EKIGELEAEIASLERSIAEKERELEDA- 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 694 cmvkeqktklaevsklkQETAANLQNQINTLEILIEDDKQksiQIELLKHEKVQLISELAakeslifglrterkvwghel 773
Cdd:TIGR02169 321 -----------------EERLAKLEAEIDKLLAEIEELER---EIEEERKRRDKLTEEYA-------------------- 360
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 774 aqqgsSLAQNRGKLEAQIESLSRENECLRKTNESDSDALRIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEkc 853
Cdd:TIGR02169 361 -----ELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIE-- 433
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 117414162 854 tqEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNRKWHDKGELLCHLETQV 921
Cdd:TIGR02169 434 --AKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA 499
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
30-148 |
1.92e-05 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 48.25 E-value: 1.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 30 DKGLQSISE-LSLDSTLHAVNLHCNNISK------IEAIDHIWNLQHLDLSSNQISR------IEGLNTLTKLCTLNLSC 96
Cdd:COG5238 194 DEGIEELAEaLTQNTTVTTLWLKRNPIGDegaeilAEALKGNKSLTTLDLSNNQIGDegvialAEALKNNTTVETLYLSG 273
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 97 NLITK------VEGLEELINLTRLNVSYNHIDDLS--GLIPLHGIKHKLRYIDLHSNRID 148
Cdd:COG5238 274 NQIGAegaialAKALQGNTTLTSLDLSVNRIGDEGaiALAEGLQGNKTLHTLNLAYNGIG 333
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
704-906 |
2.02e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.22 E-value: 2.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 704 AEVSKLKQETAANLQNQINTLEILIEDDKQksiQIELLKHEKVQLISELAAKESLIFGLRTERKVWGHELAQQGSSLAQN 783
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKK---EEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 784 RGKLEAQIESLSRENECLRKTNESDSDALRIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEKcTQEQLDEKSS 863
Cdd:COG4942 96 RAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAA-LRAELEAERA 174
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 117414162 864 QLDEVLEKLErhnERKEKLKQQLKGKEVELEEIRKAYSTLNRK 906
Cdd:COG4942 175 ELEALLAELE---EERAALEALKAERQKLLARLEKELAELAAE 214
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
66-147 |
2.39e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 42.90 E-value: 2.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 66 NLQHLDLSSNQISRIEG--LNTLTKLCTLNLSCNLITKVEGleelinltrlnvsynhiDDLSGLiplhgikHKLRYIDLH 143
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDgaFKGLSNLKVLDLSNNLLTTLSP-----------------GAFSGL-------PSLRYLDLS 57
|
....
gi 117414162 144 SNRI 147
Cdd:pfam13855 58 GNRL 61
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
571-809 |
2.43e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.84 E-value: 2.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 571 REQAQQLHQLLAlKEQEHRKELETrefftdadfQDALAKEIAKEEKKHEQMIKEYQEKIDVLSQQYMDLENEFRIALTVE 650
Cdd:COG4942 23 AEAEAELEQLQQ-EIAELEKELAA---------LKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 651 ARRFQDVKDGFENVATELAK-------SKHALIWAQRKENESSSLIKDLTCMVKEQKTKLAEVSKLKQETAAN---LQNQ 720
Cdd:COG4942 93 AELRAELEAQKEELAELLRAlyrlgrqPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALraeLEAE 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 721 INTLEILIEDDKQKSIQIELLKHEKVQLISELAAKESlifglrterkvwghELAQQGSSLAQNRGKLEAQIESLSRENEC 800
Cdd:COG4942 173 RAELEALLAELEEERAALEALKAERQKLLARLEKELA--------------ELAAELAELQQEAEELEALIARLEAEAAA 238
|
....*....
gi 117414162 801 LRKTNESDS 809
Cdd:COG4942 239 AAERTPAAG 247
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
281-885 |
3.21e-05 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 48.19 E-value: 3.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 281 EPEKNNHENDLqnEIKLQKLDDQILQLLNETSNSIDNVLEKDPRPKRDTD-ITSESDYGNRKECNRKVPRRSKIPYDAKT 359
Cdd:pfam15921 248 EALKSESQNKI--ELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANsIQSQLEIIQEQARNQNSMYMRQLSDLEST 325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 360 IQTIKhhnknynSFVSCNRKMKPPYLKELYVSSSLANcpmlQESEKPKTEIIKVDQ-SHSEDNTYQSLVEQLdQEREKRW 438
Cdd:pfam15921 326 VSQLR-------SELREAKRMYEDKIEELEKQLVLAN----SELTEARTERDQFSQeSGNLDDQLQKLLADL-HKREKEL 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 439 RAEQAENK-LMD-------YIDELHKHANEKEdihslalLTTDRLKEIIFRERNS-KGQLEVMVHKLQ------NEIKKL 503
Cdd:pfam15921 394 SLEKEQNKrLWDrdtgnsiTIDHLRRELDDRN-------MEVQRLEALLKAMKSEcQGQMERQMAAIQgkneslEKVSSL 466
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 504 TVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAqirlIQEVELKASAADREIYLLRTSLHREREQAQQLHQllal 583
Cdd:pfam15921 467 TAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTAS----LQEKERAIEATNAEITKLRSRVDLKLQELQHLKN---- 538
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 584 kEQEHRKELETRefftdadfQDALAKEIAKEEKKHE----------QMIKEYQEKIDVLSQQYMDLENEFRiALTVEARR 653
Cdd:pfam15921 539 -EGDHLRNVQTE--------CEALKLQMAEKDKVIEilrqqienmtQLVGQHGRTAGAMQVEKAQLEKEIN-DRRLELQE 608
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 654 FQDVKDGFENVATELakskhaliwaqrkENESSSLIKDLTCMVKEQKTKLAEVSKLKQE------TAANLQNQINTL--- 724
Cdd:pfam15921 609 FKILKDKKDAKIREL-------------EARVSDLELEKVKLVNAGSERLRAVKDIKQErdqllnEVKTSRNELNSLsed 675
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 725 -EILIEDDKQKSIQIELLKHE-KVQLISELAAKESLIFGLRTERKVWGHELAQQGSSLAQNRGKlEAQIESLSRENECLR 802
Cdd:pfam15921 676 yEVLKRNFRNKSEEMETTTNKlKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAK-RGQIDALQSKIQFLE 754
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 803 ktnESDSDALRIKCKIIDDQTETIRKLKDCLQEKDE----------HIKRLQEKITEIEKCtqeqLDEKSSQLDEVLEKL 872
Cdd:pfam15921 755 ---EAMTNANKEKHFLKEEKNKLSQELSTVATEKNKmagelevlrsQERRLKEKVANMEVA----LDKASLQFAECQDII 827
|
650
....*....|...
gi 117414162 873 ERHNERKEKLKQQ 885
Cdd:pfam15921 828 QRQEQESVRLKLQ 840
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
494-912 |
5.84e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 47.07 E-value: 5.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 494 HKLQNEIKKLTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAqiRLIQEVELKASAADREIYLLRTSLHREREQ 573
Cdd:COG4717 91 AELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALE--AELAELPERLEELEERLEELRELEEELEEL 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 574 AQQLHQLlalkEQEHRKELETREFFTDADFQDALAK--EIAKEEKKHEQMIKEYQEKIDVLSQQYMDLENEFRIALTVEA 651
Cdd:COG4717 169 EAELAEL----QEELEELLEQLSLATEEELQDLAEEleELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEER 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 652 RRFQDVKDGFENVATELAKSKHALIWAQRKENESSSLIKDLTCMVKEQKTKLAEVSKLKQETAANLQNQINTLEILIEDD 731
Cdd:COG4717 245 LKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEEL 324
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 732 KQKsiqIELLKHEKVQLISELAAKESLIFGLRTERKVWGHELAQQGsslaqnrgkLEAQIESLsrenecLRKTNESDSDA 811
Cdd:COG4717 325 LAA---LGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEE---------LEQEIAAL------LAEAGVEDEEE 386
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 812 LRIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEKCT-QEQLDEKSSQLDEVLEKLERHNERKEKLKQQLK--G 888
Cdd:COG4717 387 LRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEElEEELEELEEELEELEEELEELREELAELEAELEqlE 466
|
410 420
....*....|....*....|....
gi 117414162 889 KEVELEEIRKAYSTLNRKWHDKGE 912
Cdd:COG4717 467 EDGELAELLQELEELKAELRELAE 490
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
32-148 |
6.05e-05 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 46.71 E-value: 6.05e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 32 GLQSISELSLDSTLHAVNLHCNNISKiEAIDHIW-------NLQHLDLSSNQI------SRIEGLNTLTKLCTLNLSCNL 98
Cdd:COG5238 169 AAISMAKALQNNSVETVYLGCNQIGD-EGIEELAealtqntTVTTLWLKRNPIgdegaeILAEALKGNKSLTTLDLSNNQ 247
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 99 ITKvEGLEELI-------NLTRLNVSYNHIDD--LSGLIP-LHGIKHkLRYIDLHSNRID 148
Cdd:COG5238 248 IGD-EGVIALAealknntTVETLYLSGNQIGAegAIALAKaLQGNTT-LTSLDLSVNRIG 305
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
53-213 |
6.80e-05 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 46.47 E-value: 6.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 53 NNISKIEAIDHIWNLQHLDLSSNQISRIEGLNTLTKLCTLNLSCNlitkvEGLEELINLTRLNVSYNHIDDLSGLIPLHg 132
Cdd:COG4886 62 LSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN-----EELSNLTNLESLDLSGNQLTDLPEELANL- 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 133 ikHKLRYIDLHSNRIDSIHHLLQcmvGLHFLTNLILekdgDDNPVCRLPgyraVILQTLPQLRILDCKN--------IFG 204
Cdd:COG4886 136 --TNLKELDLSNNQLTDLPEPLG---NLTNLKSLDL----SNNQLTDLP----EELGNLTNLKELDLSNnqitdlpePLG 202
|
....*....
gi 117414162 205 EPVNLTEIN 213
Cdd:COG4886 203 NLTNLEELD 211
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
604-919 |
6.91e-05 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 46.96 E-value: 6.91e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 604 QDALAKeIAKEEKKHEQMIKEYQEKIDVLSQQYMDLENEFrialtVEARRFQDVKDGFENVATELAKSKHALIWAQRKEN 683
Cdd:TIGR00606 590 RDRLAK-LNKELASLEQNKNHINNELESKEEQLSSYEDKL-----FDVCGSQDEESDLERLKEEIEKSSKQRAMLAGATA 663
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 684 ESSSLIKDLTcmvkEQKTKLAEVSKLKQETAANLQNQINTLE--ILIEDDKQKSIQIELLKHEKVQLI---------SEL 752
Cdd:TIGR00606 664 VYSQFITQLT----DENQSCCPVCQRVFQTEAELQEFISDLQskLRLAPDKLKSTESELKKKEKRRDEmlglapgrqSII 739
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 753 AAKESLIFGLRTERKVWGHELAQQGSSLAQNRGKLEAQIESLSRENECLR------------KTNESDSDALRIKCKIID 820
Cdd:TIGR00606 740 DLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTdvtimerfqmelKDVERKIAQQAAKLQGSD 819
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 821 DQtETIRKLKDCLQEKDEHIKRLQEKITEIEKCTQEQlDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAY 900
Cdd:TIGR00606 820 LD-RTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQ-QEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEV 897
|
330
....*....|....*....
gi 117414162 901 STLNRKWHDKGELLCHLET 919
Cdd:TIGR00606 898 QSLIREIKDAKEQDSPLET 916
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
428-1030 |
7.21e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 47.06 E-value: 7.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 428 EQLDQEREKRWRAEQAENKLMDYIDELHKHANEKEdihslallTTDRLKEiifRERNSKGQLEVMvhKLQNEIKKLTVEL 507
Cdd:PTZ00121 1281 DELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAK--------KADEAKK---KAEEAKKKADAA--KKKAEEAKKAAEA 1347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 508 MKAKDQqedhlKHLRTLEKTLEKMERQKRQQqaaqirliQEVELKASAADREIyllrtslhREREQAQQLHQllalKEQE 587
Cdd:PTZ00121 1348 AKAEAE-----AAADEAEAAEEKAEAAEKKK--------EEAKKKADAAKKKA--------EEKKKADEAKK----KAEE 1402
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 588 HRKELETREFFTDADFQDALAKEIAKEEKKHEQMIKEYQE--KIDVLSQQymdlenefrialTVEARRFQDVKDGfenvA 665
Cdd:PTZ00121 1403 DKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEakKADEAKKK------------AEEAKKAEEAKKK----A 1466
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 666 TELAKSKHALIWAQRKENESSSLIKDLTCMVKEQKTKLAEVSKLKQETAANLQNQINTLEILIEDDKQKSIqiELLKHEK 745
Cdd:PTZ00121 1467 EEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKAD--EAKKAEE 1544
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 746 VQLISELAAKESLifglrteRKvwghelaqqgsslAQNRGKLEAQIESLSRENECLRKTNES-DSDALRIKCKIIDDQTE 824
Cdd:PTZ00121 1545 KKKADELKKAEEL-------KK-------------AEEKKKAEEAKKAEEDKNMALRKAEEAkKAEEARIEEVMKLYEEE 1604
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 825 TIRKLKDCLQEKDEHIKRLQEKITEIEKCTQEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVE----LEEIRKAY 900
Cdd:PTZ00121 1605 KKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEdkkkAEEAKKAE 1684
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 901 STLNRKwhdKGELLCHLETQVKEVKEKFENKEKKLKAER-DKSIELQKNAMEKLHSMDDAFKRQVDA--IVEAHQAEIAQ 977
Cdd:PTZ00121 1685 EDEKKA---AEALKKEAEEAKKAEELKKKEAEEKKKAEElKKAEEENKIKAEEAKKEAEEDKKKAEEakKDEEEKKKIAH 1761
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|...
gi 117414162 978 LANEKQKCIDSANLKVHQIEKEmrELLEETCKNKKTMEAKIKQLAFALNEIQQ 1030
Cdd:PTZ00121 1762 LKKEEEKKAEEIRKEKEAVIEE--ELDEEDEKRRMEVDKKIKDIFDNFANIIE 1812
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
484-735 |
8.35e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.30 E-value: 8.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 484 NSKGQLEVMVHKLQNEIKKLTVELMKAKDQQEDHLKHLRTLEKTLEKMErqkrqqqaaqiRLIQEVELKASAADREIYLL 563
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALA-----------RRIRALEQELAALEAELAEL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 564 RTSLHREREQAQQLHQLLA--------LKEQEHRKELETREFFTDADFQDALAKEIAKEEKkheQMIKEYQEKIDVLSQQ 635
Cdd:COG4942 89 EKEIAELRAELEAQKEELAellralyrLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARR---EQAEELRADLAELAAL 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 636 YMDLENEfrialtvearrfqdvKDGFENVATELAKSKHALiwaQRKENESSSLIKDLTcmvKEQKTKLAEVSKLKQEtAA 715
Cdd:COG4942 166 RAELEAE---------------RAELEALLAELEEERAAL---EALKAERQKLLARLE---KELAELAAELAELQQE-AE 223
|
250 260
....*....|....*....|
gi 117414162 716 NLQNQINTLEILIEDDKQKS 735
Cdd:COG4942 224 ELEALIARLEAEAAAAAERT 243
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
855-1032 |
1.28e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.53 E-value: 1.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 855 QEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKFENKEKK 934
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 935 LKAERDKsIELQKNAMEKLH------------SMDDAFKRQ--VDAIVEAHQAEIAQLANEKQKcIDSANLKVHQIEKEM 1000
Cdd:COG4942 99 LEAQKEE-LAELLRALYRLGrqpplalllspeDFLDAVRRLqyLKYLAPARREQAEELRADLAE-LAALRAELEAERAEL 176
|
170 180 190
....*....|....*....|....*....|..
gi 117414162 1001 RELLEETCKNKKTMEAKIKQLAFALNEIQQDM 1032
Cdd:COG4942 177 EALLAELEEERAALEALKAERQKLLARLEKEL 208
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
697-906 |
1.35e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.53 E-value: 1.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 697 KEQKTKLAEVSKLKQETAANLQNQINTLEILIEDDKQKSIQIELLKHEKVQLISELAAKESLIFGLRTErkvwgheLAQQ 776
Cdd:COG4942 23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE-------IAEL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 777 GSSLAQNRGKLEAQIESLSRENEC----LRKTNESDSDALRIK------CKIIDDQTETIRKLKDCLQEKDEHIKRLQEK 846
Cdd:COG4942 96 RAELEAQKEELAELLRALYRLGRQpplaLLLSPEDFLDAVRRLqylkylAPARREQAEELRADLAELAALRAELEAERAE 175
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 847 ITEIEKCTQEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNRK 906
Cdd:COG4942 176 LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
43-123 |
1.37e-04 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 45.55 E-value: 1.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 43 STLHAVNLHCNNISKIEAI---DHIW---NLQHLDLSSNQISR------IEGLNTLTKLCTLNLSCNLITKvEGLEELI- 109
Cdd:COG5238 320 KTLHTLNLAYNGIGAQGAIalaKALQentTLHSLDLSDNQIGDegaialAKYLEGNTTLRELNLGKNNIGK-QGAEALId 398
|
90
....*....|....*....
gi 117414162 110 -----NLTRLNVSYNHIDD 123
Cdd:COG5238 399 alqtnRLHTLILDGNLIGA 417
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
412-1027 |
1.92e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 45.68 E-value: 1.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 412 KVDQSHSEDNTYQSLVEQLDQEREKRwRAEQAENKLMDYIDELHKHANEKEDIHSLALLTTDRLKEIIFRERNSKGQLev 491
Cdd:COG4913 263 RYAAARERLAELEYLRAALRLWFAQR-RLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDR-- 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 492 mVHKLQNEIKKLTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRLIQEVELKASAADREIYLLRTSLHRER 571
Cdd:COG4913 340 -LEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLR 418
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 572 EQAQQLHQLLAlkeqehrkELETREFFTDADFQDALAkEIAKEEKKHEQMIKEYQEKIDVLSqqymdlENE--------- 642
Cdd:COG4913 419 RELRELEAEIA--------SLERRKSNIPARLLALRD-ALAEALGLDEAELPFVGELIEVRP------EEErwrgaierv 483
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 643 ---FRIALTVEARRFQDVKDGFENVATELA----KSKHALIWAQRKENESSSLIKDLTcmVKEQ------KTKLAEVSKL 709
Cdd:COG4913 484 lggFALTLLVPPEHYAAALRWVNRLHLRGRlvyeRVRTGLPDPERPRLDPDSLAGKLD--FKPHpfrawlEAELGRRFDY 561
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 710 KQ-ETAANLQNQintleilieddkQKSIQIE-LLKHEKV--QLISELAAKESLIFGLRTERKVwgHELAQQGSSLAQNRG 785
Cdd:COG4913 562 VCvDSPEELRRH------------PRAITRAgQVKGNGTrhEKDDRRRIRSRYVLGFDNRAKL--AALEAELAELEEELA 627
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 786 KLEAQIESLSREneclRKTNESDSDALRikcKIIDDQTETIRklkdcLQEKDEHIKRLQEKITEIEKcTQEQLDEKSSQL 865
Cdd:COG4913 628 EAEERLEALEAE----LDALQERREALQ---RLAEYSWDEID-----VASAEREIAELEAELERLDA-SSDDLAALEEQL 694
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 866 DEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNRKWHDKGELLC-----HLETQVKEVKEKFENKEKKLK--AE 938
Cdd:COG4913 695 EELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARlelraLLEERFAAALGDAVERELRENleER 774
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 939 RDKSIELQKNAMEKLHSMDDAFKRQVDAIVEAHQAEIAQLANEKQKCIDSANLKVHQIEKEMRELLeetcknKKTMEAKI 1018
Cdd:COG4913 775 IDALRARLNRAEEELERAMRAFNREWPAETADLDADLESLPEYLALLDRLEEDGLPEYEERFKELL------NENSIEFV 848
|
....*....
gi 117414162 1019 KQLAFALNE 1027
Cdd:COG4913 849 ADLLSKLRR 857
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
452-1032 |
1.98e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 45.34 E-value: 1.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 452 DELHKHANEKEDIHSLALLTTDRLKEIIFRERNSKGQLEVMVHKLQNEIKKLTVELMKAKDQQEDHLKhlrTLEKTLEKM 531
Cdd:TIGR00618 155 AQFLKAKSKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQ---VLEKELKHL 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 532 ERQKRQQQAAQIRLIQEVELKASaadreiyllRTSLHREREQAQQLHQLLALKEQEHRKELETREFFTDADFQDALAKEI 611
Cdd:TIGR00618 232 REALQQTQQSHAYLTQKREAQEE---------QLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAV 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 612 AKEEKKHEQMIKEYQEKIDVLS----------QQYMDLENEFRIALTVEA-----RRFQDVKDGF-ENVATELAKSKHAL 675
Cdd:TIGR00618 303 TQIEQQAQRIHTELQSKMRSRAkllmkraahvKQQSSIEEQRRLLQTLHSqeihiRDAHEVATSIrEISCQQHTLTQHIH 382
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 676 IWAQRKE------NESSSLIKDLTCMVKEQKTKLAEVSKLKQETAANLQNQINTLEILIEDDKQKSIQIELLKHEKVQLI 749
Cdd:TIGR00618 383 TLQQQKTtltqklQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQ 462
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 750 SELAAKESLIFGLRTERKVWGHElaqqgsslaQNRGKLEAQIESLSRENECLRKTNESDSDALRIK-----------CKI 818
Cdd:TIGR00618 463 ESAQSLKEREQQLQTKEQIHLQE---------TRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDidnpgpltrrmQRG 533
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 819 IDDQT---ETIRKLKDCLQEKDEHIKRLQEKITEIEKCTQeQLDEKSSQLDEVLEKLERHNERKEKLKQ-QLKGKEVELE 894
Cdd:TIGR00618 534 EQTYAqleTSEEDVYHQLTSERKQRASLKEQMQEIQQSFS-ILTQCDNRSKEDIPNLQNITVRLQDLTEkLSEAEDMLAC 612
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 895 EIRKAYSTLNRKWHDKGELL----CHLETQVKEVKEKFENKEKKLKAERDKSIELQKNAMEKLhsmddafkRQVDAIVEA 970
Cdd:TIGR00618 613 EQHALLRKLQPEQDLQDVRLhlqqCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELL--------ASRQLALQK 684
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 117414162 971 HQAEIAQLANEKQKC--IDSANLKVHQIEKEMRELLEETCKNKKTMEAKIKQLAFALNEIQQDM 1032
Cdd:TIGR00618 685 MQSEKEQLTYWKEMLaqCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKEL 748
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
400-981 |
2.63e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 45.05 E-value: 2.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 400 LQESEKPKTEIIKvdqshsEDNTYQSLVEQLDQEREKRWRAEQAENKLMDYIDELHKhanEKEDIHSLALLTTDRLKEII 479
Cdd:PRK03918 195 IKEKEKELEEVLR------EINEISSELPELREELEKLEKEVKELEELKEEIEELEK---ELESLEGSKRKLEEKIRELE 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 480 FRERNSKGQLEVMVHKLQ--NEIKKLTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQqaaqIRLIQEVELKASAAD 557
Cdd:PRK03918 266 ERIEELKKEIEELEEKVKelKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGI----EERIKELEEKEERLE 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 558 ---REIYLLRTSLHREREQAQQLHQLLALKEQ--EHRKELETREfftdadfqdalAKEIAKEEKKHEQMIKEYQEKIDVL 632
Cdd:PRK03918 342 elkKKLKELEKRLEELEERHELYEEAKAKKEEleRLKKRLTGLT-----------PEKLEKELEELEKAKEEIEEEISKI 410
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 633 SQQYMDLENefrialtvearRFQDVKDGFEnvATELAKSKHALIWAQRKENESSSLIKDLTCMVKEQKTKLAEVSKLKQE 712
Cdd:PRK03918 411 TARIGELKK-----------EIKELKKAIE--ELKKAKGKCPVCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERK 477
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 713 TAANLQNQINTLEILIEDDKQKSI--QIELLKHE-KVQLISELAAKESLIFGLRTERKvwghELAQQGSSLAQNRGKLEA 789
Cdd:PRK03918 478 LRKELRELEKVLKKESELIKLKELaeQLKELEEKlKKYNLEELEKKAEEYEKLKEKLI----KLKGEIKSLKKELEKLEE 553
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 790 QIESLSRENECLRKTNESDSDALRI----KCKIIDDQTETIRKLKDCLQEKDE---HIKRLQEKITEIEKCtQEQLDEKS 862
Cdd:PRK03918 554 LKKKLAELEKKLDELEEELAELLKEleelGFESVEELEERLKELEPFYNEYLElkdAEKELEREEKELKKL-EEELDKAF 632
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 863 SQLDEVLEKLERHNERKEKLKQqlKGKEVELEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKFENKEKKLKA--ERD 940
Cdd:PRK03918 633 EELAETEKRLEELRKELEELEK--KYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEreKAK 710
|
570 580 590 600
....*....|....*....|....*....|....*....|.
gi 117414162 941 KSIELQKNAMEKLHSMDDAFKRQVDAIVEAHQAEIAQLANE 981
Cdd:PRK03918 711 KELEKLEKALERVEELREKVKKYKALLKERALSKVGEIASE 751
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
786-983 |
4.77e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 43.99 E-value: 4.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 786 KLEAQIESLSRENECLRKTNESDSDALRIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKIteiekctqEQLDEKSSQL 865
Cdd:COG4717 50 RLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAEL--------EELREELEKL 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 866 DEVLEKLERHNERKEkLKQQLKGKEVELEEIRKAYstlnRKWHDKGELLCHLETQVKEVKEKFENKEKKLKAERDKSIEL 945
Cdd:COG4717 122 EKLLQLLPLYQELEA-LEAELAELPERLEELEERL----EELRELEEELEELEAELAELQEELEELLEQLSLATEEELQD 196
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 117414162 946 QKNAMEKLHSMDDAFKRQVDAI---VEAHQAEIAQLANEKQ 983
Cdd:COG4717 197 LAEELEELQQRLAELEEELEEAqeeLEELEEELEQLENELE 237
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
401-860 |
5.11e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 44.36 E-value: 5.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 401 QESEKPKTEIIKVDQSHSEDNTYQSLVEQLDQEREKRWRAEQAENKLMDY--IDELHKHANEKEDIHSLALLTTDRLK-E 477
Cdd:PTZ00121 1381 DAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKkkADEAKKKAEEAKKADEAKKKAEEAKKaE 1460
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 478 IIFRERNSKGQLEVMvhKLQNEIKKLTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRLIQEVELKASAAD 557
Cdd:PTZ00121 1461 EAKKKAEEAKKADEA--KKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADE 1538
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 558 reiylLRTSlhREREQAQQLHQLLALKEQEHRKELETREFFTDADFQDALAKEIAK--EEKKHEQMIKEYQEKIDVLSQQ 635
Cdd:PTZ00121 1539 -----AKKA--EEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKkaEEARIEEVMKLYEEEKKMKAEE 1611
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 636 YMDLENEFRIAltVEARRFQDVKDGFENVATELAKSKHALiwAQRKENESSSLIKdltcmvKEQKTKLAEVSKLKQETAA 715
Cdd:PTZ00121 1612 AKKAEEAKIKA--EELKKAEEEKKKVEQLKKKEAEEKKKA--EELKKAEEENKIK------AAEEAKKAEEDKKKAEEAK 1681
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 716 NLqnqintleiliEDDKQKSIQIELLKHEKVQLISELAAKESlifglrtERKVWGHELAQQGSSLAQNRGKLEAQIESLS 795
Cdd:PTZ00121 1682 KA-----------EEDEKKAAEALKKEAEEAKKAEELKKKEA-------EEKKKAEELKKAEEENKIKAEEAKKEAEEDK 1743
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 796 RENECLRKTNESDSDALRIKcKIIDDQTETIRK-----LKDCLQEKDEHIKRLQEKITEIEKCTQEQLDE 860
Cdd:PTZ00121 1744 KKAEEAKKDEEEKKKIAHLK-KEEEKKAEEIRKekeavIEEELDEEDEKRRMEVDKKIKDIFDNFANIIE 1812
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
774-984 |
5.18e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.60 E-value: 5.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 774 AQQGSSLAQNRGKLEAQIESLSRENECLRKTNESDSDALRIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEKc 853
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA- 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 854 tqeQLDEKSSQLDEVLEKLERhNERKEKLKQQLKGKEV-ELEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKFENKE 932
Cdd:COG4942 98 ---ELEAQKEELAELLRALYR-LGRQPPLALLLSPEDFlDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAER 173
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 117414162 933 KKLKAERDKsIELQKNAMEKLHSMDDAFKRQVDAIVEAHQAEIAQLANEKQK 984
Cdd:COG4942 174 AELEALLAE-LEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
784-898 |
6.73e-04 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 43.61 E-value: 6.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 784 RGKLEAQIESLSRENECLRKtnESDSDALRIKCKIIDDQTETIRKLKDCLQ----EKDEHIKRLQEKITEIEkctqEQLD 859
Cdd:PRK12704 26 KKIAEAKIKEAEEEAKRILE--EAKKEAEAIKKEALLEAKEEIHKLRNEFEkelrERRNELQKLEKRLLQKE----ENLD 99
|
90 100 110
....*....|....*....|....*....|....*....
gi 117414162 860 EKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRK 898
Cdd:PRK12704 100 RKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIE 138
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
408-896 |
6.83e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 43.77 E-value: 6.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 408 TEIIKVDQSHSEDNtyQSLVEQLDQEREKRWRAEQAENKLMDYIDELHKHANEKEDIHSLALLTTDRLKEIIFRERNSKG 487
Cdd:COG1196 267 AELEELRLELEELE--LELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEE 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 488 QLEVMVHKLQNEIKKLTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRLIQEVELKASAADREIYLLRTSL 567
Cdd:COG1196 345 ELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELE 424
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 568 HREREQAQQLHQLLALKEQEHRKELETREFFTD-ADFQDALAKEIAKEEKKHEQMIKEYQEKIDVLSQQYMDLENEFRIA 646
Cdd:COG1196 425 ELEEALAELEEEEEEEEEALEEAAEEEAELEEEeEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYE 504
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 647 LTVEARRFQDVKDGFENVATELAkskhALIWAQRK-----ENESSSLIKDLTCMVKEQKTKLAEVSKLKQETAANLQ--N 719
Cdd:COG1196 505 GFLEGVKAALLLAGLRGLAGAVA----VLIGVEAAyeaalEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLplD 580
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 720 QINTLEILI---------------------EDDKQKSIQIELLKHEKVQLISELAAKES-LIFGLRTERKVWGHELAQQG 777
Cdd:COG1196 581 KIRARAALAaalargaigaavdlvasdlreADARYYVLGDTLLGRTLVAARLEAALRRAvTLAGRLREVTLEGEGGSAGG 660
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 778 SSLAQNRGKLEAQIESLSRENECLRKTNESDSDALRIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEKCTQEQ 857
Cdd:COG1196 661 SLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEE 740
|
490 500 510
....*....|....*....|....*....|....*....
gi 117414162 858 LDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEI 896
Cdd:COG1196 741 LLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
87-127 |
8.02e-04 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 38.00 E-value: 8.02e-04
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 117414162 87 TKLCTLNLSCNLITKVEGLEELINLTRLNVSYN-HIDDLSGL 127
Cdd:pfam12799 1 PNLEVLDLSNNQITDIPPLAKLPNLETLDLSGNnKITDLSDL 42
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
706-906 |
9.43e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 43.22 E-value: 9.43e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 706 VSKLKQETAANLQNQINTLEILIEDDKQKSIQIELLKHEK---VQLISELAAKESLIFGLRTERKVWGHEL-----AQQG 777
Cdd:COG4717 48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEeeyAELQEELEELEEELEELEAELEELREELeklekLLQL 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 778 SSLAQNRGKLEAQIESLSRENECLRKtnesdsdalrikckiiddQTETIRKLKDCLQEKDEHIKRLQEKITEIEKCTQEq 857
Cdd:COG4717 128 LPLYQELEALEAELAELPERLEELEE------------------RLEELRELEEELEELEAELAELQEELEELLEQLSL- 188
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 117414162 858 ldEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNRK 906
Cdd:COG4717 189 --ATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENE 235
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
43-99 |
1.16e-03 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 38.27 E-value: 1.16e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 117414162 43 STLHAVNLHCNNISKI--EAIDHIWNLQHLDLSSNQISRIEG--LNTLTKLCTLNLSCNLI 99
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLddGAFKGLSNLKVLDLSNNLLTTLSPgaFSGLPSLRYLDLSGNRL 61
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
678-923 |
1.32e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 42.70 E-value: 1.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 678 AQRKENESSSLIKDLTCMVKEQKTKLAEVSKLKQETAaNLQNQINTLEILIEDDKQK-----------SIQIELLKHEKV 746
Cdd:TIGR04523 407 NQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIK-DLTNQDSVKELIIKNLDNTresletqlkvlSRSINKIKQNLE 485
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 747 QLISELAAKESLIFGLRTERKvwghELAQQGSSLAQNRGKLEAQIESLsrENECLRKTNESDSdalrIKCKII-DDQTET 825
Cdd:TIGR04523 486 QKQKELKSKEKELKKLNEEKK----ELEEKVKDLTKKISSLKEKIEKL--ESEKKEKESKISD----LEDELNkDDFELK 555
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 826 IRKLKDCLQEKDEHIKRLQEKITEIEKCT---QEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYST 902
Cdd:TIGR04523 556 KENLEKEIDEKNKEIEELKQTQKSLKKKQeekQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKN 635
|
250 260
....*....|....*....|.
gi 117414162 903 LNRKWHDKGELLCHLETQVKE 923
Cdd:TIGR04523 636 IKSKKNKLKQEVKQIKETIKE 656
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
473-677 |
1.95e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.67 E-value: 1.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 473 DRLKEIIFRERNSKGQLEVMVHKLQNEIKKLTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRLIQ----- 547
Cdd:COG4942 37 AELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRalyrl 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 548 ----EVELKASAAD-----REIYLLRTSLHREREQAQQLHQLLA-LKEQEHRKELETREFFTDADFQDALAKEIAKEEKK 617
Cdd:COG4942 117 grqpPLALLLSPEDfldavRRLQYLKYLAPARREQAEELRADLAeLAALRAELEAERAELEALLAELEEERAALEALKAE 196
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 117414162 618 HEQMIKEYQEKIDVLSQQYMDL-ENEFRIALTVEARRFQDVKDGFENVATELAKSKHALIW 677
Cdd:COG4942 197 RQKLLARLEKELAELAAELAELqQEAEELEALIARLEAEAAAAAERTPAAGFAALKGKLPW 257
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
662-895 |
2.11e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 42.36 E-value: 2.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 662 ENVATELAKSKHALIWAQRKENESSSLIKDLTCMVKEQKTKLAEVSKLKQETAANLQNQINTLEILIEDDKQKSIQIELL 741
Cdd:TIGR02169 677 QRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENV 756
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 742 KHEKVQLISELAAKESLIFGLRTERKVWGHELAQQGssLAQNRGKLEAQIESLSRENECLRKTNESDSDALRIKCKIIDD 821
Cdd:TIGR02169 757 KSELKELEARIEELEEDLHKLEEALNDLEARLSHSR--IPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKE 834
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 117414162 822 QTETIRKLKDCLQEKDEHIKRLQEKITEIEKcTQEQLDEKSS---QLDEVLEKLERHNERKEKLKQQLKGKEVELEE 895
Cdd:TIGR02169 835 IQELQEQRIDLKEQIKSIEKEIENLNGKKEE-LEEELEELEAalrDLESRLGDLKKERDELEAQLRELERKIEELEA 910
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
473-772 |
2.43e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 41.98 E-value: 2.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 473 DRLKeiifRERNSKGQLEVMVHKLQN-EIKKLTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQA---AQIRLIQE 548
Cdd:TIGR02169 201 ERLR----REREKAERYQALLKEKREyEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKrleEIEQLLEE 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 549 VELKASA-ADREIYLLRTSLHREREQAQQLHQLLALKEQEhRKELETREFFTDADFQ------DALAKEIAKEEKKHEQM 621
Cdd:TIGR02169 277 LNKKIKDlGEEEQLRVKEKIGELEAEIASLERSIAEKERE-LEDAEERLAKLEAEIDkllaeiEELEREIEEERKRRDKL 355
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 622 IKEYQE---KIDVLSQQYMDLENEFRIALtveaRRFQDVKDGFENVATELAKSKHALIWAQRKENESSSLIKDLTCMVKE 698
Cdd:TIGR02169 356 TEEYAElkeELEDLRAELEEVDKEFAETR----DELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAG 431
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 117414162 699 QKTKLAEVSKLKQETAANLQNQINTLEILIEDDKQKSIQIELLKHEKVQLISELAAKESLIFGLRTERKVWGHE 772
Cdd:TIGR02169 432 IEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEER 505
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
110-169 |
2.76e-03 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 37.12 E-value: 2.76e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 110 NLTRLNVSYNHIDDLSGLIPLHGikHKLRYIDLHSNRIDSIHhlLQCMVGLHFLTNLILE 169
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGL--SNLKVLDLSNNLLTTLS--PGAFSGLPSLRYLDLS 57
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
567-1028 |
2.92e-03 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 41.81 E-value: 2.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 567 LHREREQAQQLHQLlALKEQEHRKElETREFFTDADFQDALAKEIAKEEKKhEQMIKEYQEKIDVLSQQYMDLENEFRIA 646
Cdd:PRK01156 216 TLKEIERLSIEYNN-AMDDYNNLKS-ALNELSSLEDMKNRYESEIKTAESD-LSMELEKNNYYKELEERHMKIINDPVYK 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 647 LTVEARRF-------QDVKDGFENVATELAKSKHALiwaqRKENESSSLIKDLTCMVKEQKTKLAEVSKLKqETAANLQN 719
Cdd:PRK01156 293 NRNYINDYfkykndiENKKQILSNIDAEINKYHAII----KKLSVLQKDYNDYIKKKSRYDDLNNQILELE-GYEMDYNS 367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 720 QINTLEILIEDDKQKSIQIELLKHEKVQLISELAAKESLIFGLRTERKVWGHELAQQGSSLAQNRGKLEAQIESLSRENE 799
Cdd:PRK01156 368 YLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNME 447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 800 CLRKTNesdsdalriKCKIIDDQTETiRKLKDCLQEKDEHIKRLQEKITEIEKcTQEQLDEKSSQLDEVLEKLERHN-ER 878
Cdd:PRK01156 448 MLNGQS---------VCPVCGTTLGE-EKSNHIINHYNEKKSRLEEKIREIEI-EVKDIDEKIVDLKKRKEYLESEEiNK 516
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 879 KEKLKQQLKGKEVELEEIRKAYSTLNRKwHDKGELLCHLETQVKEVKEKFENKEKKLKAERDKSIE---LQKNAMEKLHS 955
Cdd:PRK01156 517 SINEYNKIESARADLEDIKIKINELKDK-HDKYEEIKNRYKSLKLEDLDSKRTSWLNALAVISLIDietNRSRSNEIKKQ 595
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 117414162 956 MDDAFKRQVDAIVEAHQAE--IAQLANEKQKCIDSANLKVHQIE--KEMRELLEETCKNKKTMEAKIKQLAFALNEI 1028
Cdd:PRK01156 596 LNDLESRLQEIEIGFPDDKsyIDKSIREIENEANNLNNKYNEIQenKILIEKLRGKIDNYKKQIAEIDSIIPDLKEI 672
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
786-898 |
3.46e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 41.38 E-value: 3.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 786 KLEAQIESLSRENECLRKT-NESDSDALRIKCKIIDDQTETIRKLKdclqeKDEHIKRLQEKIteiekctqEQLDEKSSQ 864
Cdd:COG2433 417 RLEEQVERLEAEVEELEAElEEKDERIERLERELSEARSEERREIR-----KDREISRLDREI--------ERLERELEE 483
|
90 100 110
....*....|....*....|....*....|....*
gi 117414162 865 LDEVLEKLERHNER-KEKLKQQLKGKEVELEEIRK 898
Cdd:COG2433 484 ERERIEELKRKLERlKELWKLEHSGELVPVKVVEK 518
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
410-896 |
3.92e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 41.11 E-value: 3.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 410 IIKVDQSHSEDNT-YQSLVEQLDQEREKRWRAEQAENKLMDY---IDELHKHANEKEDIHSLALL---TTDRLKEIIFRE 482
Cdd:TIGR00618 302 VTQIEQQAQRIHTeLQSKMRSRAKLLMKRAAHVKQQSSIEEQrrlLQTLHSQEIHIRDAHEVATSireISCQQHTLTQHI 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 483 RNSKGQLEVMVHKLQNeIKKLTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRLIQEVELKASAADREIYL 562
Cdd:TIGR00618 382 HTLQQQKTTLTQKLQS-LCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIH 460
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 563 LRTSLHREREQAQQLHQLLALKEQEHRKeletrefftdadfqdalakeiakeEKKHEQMIKEYQEKIDVLSQQYMDLENE 642
Cdd:TIGR00618 461 LQESAQSLKEREQQLQTKEQIHLQETRK------------------------KAVVLARLLELQEEPCPLCGSCIHPNPA 516
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 643 FRIALTVEA--RRFQDVKDGFENVATELAKSKHALI----WAQRKENESSSLIKDLtcmvkeqkTKLAEVSKLKQETAAN 716
Cdd:TIGR00618 517 RQDIDNPGPltRRMQRGEQTYAQLETSEEDVYHQLTserkQRASLKEQMQEIQQSF--------SILTQCDNRSKEDIPN 588
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 717 LQNQINTLEILIEDDKQKSIQIELLKHEKVQLISELAAKESLIFglrterkvwghELAQQGSSLAQNRGKLEAQIESLS- 795
Cdd:TIGR00618 589 LQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRL-----------HLQQCSQELALKLTALHALQLTLTq 657
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 796 -RENECLRKTNESDSDALRIKCKIIDDQTETIRKL---KDCLQEKDEHIKRLQEKITEIEKCTQEQLDEKSSQLDEVLEK 871
Cdd:TIGR00618 658 eRVREHALSIRVLPKELLASRQLALQKMQSEKEQLtywKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAR 737
|
490 500
....*....|....*....|....*
gi 117414162 872 LERHNERKEKLKQQLKGKEVELEEI 896
Cdd:TIGR00618 738 EDALNQSLKELMHQARTVLKARTEA 762
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
66-130 |
4.62e-03 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 40.99 E-value: 4.62e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 117414162 66 NLQHLDLSSNQISRI--EGLNTLTKLCTLNLSCNLITKV--EGLEELINLTRLNVSYNhidDLSGLIPL 130
Cdd:PLN00113 476 RLENLDLSRNQFSGAvpRKLGSLSELMQLKLSENKLSGEipDELSSCKKLVSLDLSHN---QLSGQIPA 541
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
45-145 |
5.05e-03 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 40.42 E-value: 5.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 45 LHAVNLHCNNISKIEAID------HIWNLQHLDLSSNQISRiEGLNTL--------TKLCTLNLSCNLITKV------EG 104
Cdd:cd00116 195 LEVLDLNNNGLTDEGASAlaetlaSLKSLEVLNLGDNNLTD-AGAAALasallspnISLLTLSLSCNDITDDgakdlaEV 273
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 117414162 105 LEELINLTRLNVSYNHI----DDLSGLIpLHGIKHKLRYIDLHSN 145
Cdd:cd00116 274 LAEKESLLELDLRGNKFgeegAQLLAES-LLEPGNELESLWVKDD 317
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
712-916 |
5.40e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 40.67 E-value: 5.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 712 ETAANLQNQINTLEIL---IEDDKQksiQIELLKH--EKVQLISELAAKESLIFGLRTERKVWGHE-----LAQQGSSLA 781
Cdd:COG4913 225 EAADALVEHFDDLERAheaLEDARE---QIELLEPirELAERYAAARERLAELEYLRAALRLWFAQrrlelLEAELEELR 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 782 QNRGKLEAQIESLS--------RENECLRKTNESDSDAL-RIKcKIIDDQTETIRKLKDCLQEKDEHIKRLQEKI----- 847
Cdd:COG4913 302 AELARLEAELERLEarldalreELDELEAQIRGNGGDRLeQLE-REIERLERELEERERRRARLEALLAALGLPLpasae 380
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 117414162 848 --TEIEKCTQEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNRKWHDKGELLCH 916
Cdd:COG4913 381 efAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAE 451
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
402-958 |
7.17e-03 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 40.48 E-value: 7.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 402 ESEKPKTEIIKVDQSHSEDN---TYQSLVEQLDQER-EKRWRAEQAENKLMDYIDELHKHANEKEDIHSLALLTT----D 473
Cdd:pfam05483 175 EYEREETRQVYMDLNNNIEKmilAFEELRVQAENARlEMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQItekeN 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 474 RLKEIIF---RERNSKGQLEVMV--------------HKLQNEIKKLTVELMKAKDQQEDHLKHLRTLEKTL-----EKM 531
Cdd:pfam05483 255 KMKDLTFlleESRDKANQLEEKTklqdenlkeliekkDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTIcqlteEKE 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 532 ERQKRQQQAAQIRLIQEVELKASAADREiYLLRTSLHREREQAQQLH-----------QLLALKEQEHRKELETREFFTD 600
Cdd:pfam05483 335 AQMEELNKAKAAHSFVVTEFEATTCSLE-ELLRTEQQRLEKNEDQLKiitmelqkkssELEEMTKFKNNKEVELEELKKI 413
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 601 ADFQDALAKEIAKEEKKHEQMIKEYQEKIDVLS---QQYMDLENEFRIALTVEARRFQDVKDGFENVATELAKSKHALIW 677
Cdd:pfam05483 414 LAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQareKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAH 493
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 678 AQRKENESSSLIKDLTCMVKEQKTKLAEVSKLKQETAANLQnQINTLEiliEDDKQKSIQIELLKHEKVQLISELAAK-- 755
Cdd:pfam05483 494 CDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLK-QIENLE---EKEMNLRDELESVREEFIQKGDEVKCKld 569
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 756 -----ESLIFGLRTERKVWGHELAQQGSSLAQNRGKLEAQIESLSRENECLRKTNESDS---DALRIKCKIIDDQTETIR 827
Cdd:pfam05483 570 kseenARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENkqlNAYEIKVNKLELELASAK 649
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 828 K----LKDCLQEKDEHIKRLQEKIT-EIEKCT---------QEQLDEKSS-QLDEVLEKLERHNERKEKLkqqlkgkeve 892
Cdd:pfam05483 650 QkfeeIIDNYQKEIEDKKISEEKLLeEVEKAKaiadeavklQKEIDKRCQhKIAEMVALMEKHKHQYDKI---------- 719
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 117414162 893 LEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKFENKEKKLKAERDKSIELQKNAMEKLHSMDD 958
Cdd:pfam05483 720 IEERDSELGLYKNKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKD 785
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
506-1006 |
8.18e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 40.28 E-value: 8.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 506 ELMKAKdQQEDHLKHLRTLEKTLEKMERQkrqqqaaqIRLIQEVELKASA--ADREIYLLRTSLHREREQAQQLHQLLAL 583
Cdd:COG4913 243 ALEDAR-EQIELLEPIRELAERYAAARER--------LAELEYLRAALRLwfAQRRLELLEAELEELRAELARLEAELER 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 584 KEQEH----RKELETREFFTDADFQ--DALAKEIAKEEKKHEQM---IKEYQEKIDVLSQQYMDLENEFRIALTVEARRF 654
Cdd:COG4913 314 LEARLdalrEELDELEAQIRGNGGDrlEQLEREIERLERELEERerrRARLEALLAALGLPLPASAEEFAALRAEAAALL 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 655 QDVKDGFENVATELAKSKHALIWAQRKENESSSLIKDLtcmvKEQKTKL-AEVSKLKQETAANLQN------------QI 721
Cdd:COG4913 394 EALEEELEALEEALAEAEAALRDLRRELRELEAEIASL----ERRKSNIpARLLALRDALAEALGLdeaelpfvgeliEV 469
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 722 NTLE-----------------ILIED-------------DKQKSIQIELLKHEKVQLISELAAKESLIFGLRTERKVWG- 770
Cdd:COG4913 470 RPEEerwrgaiervlggfaltLLVPPehyaaalrwvnrlHLRGRLVYERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRa 549
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 771 ---HELAQQGS-----SLAQ----------------NRGKLEAQIESLSRENECLRKTN-------ESDSDALRIKCKII 819
Cdd:COG4913 550 wleAELGRRFDyvcvdSPEElrrhpraitragqvkgNGTRHEKDDRRRIRSRYVLGFDNraklaalEAELAELEEELAEA 629
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 820 DDQTETIRKLKDCLQEKDEHIKRLQEKI-TEIE-KCTQEQLDEKSSQLDEVLE---KLERHNERKEKLKQQLKGKEVELE 894
Cdd:COG4913 630 EERLEALEAELDALQERREALQRLAEYSwDEIDvASAEREIAELEAELERLDAssdDLAALEEQLEELEAELEELEEELD 709
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 895 EIRKAYSTLNRKWHDKGELLCHLETQVkevkekfenkekkLKAERDKSIELQKNAMEKLHsmDDAFKRQVDAIVEAHQAE 974
Cdd:COG4913 710 ELKGEIGRLEKELEQAEEELDELQDRL-------------EAAEDLARLELRALLEERFA--AALGDAVERELRENLEER 774
|
570 580 590
....*....|....*....|....*....|..
gi 117414162 975 IAQLANEKQKCIDsanlkvhQIEKEMRELLEE 1006
Cdd:COG4913 775 IDALRARLNRAEE-------ELERAMRAFNRE 799
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
772-1030 |
8.44e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 40.11 E-value: 8.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 772 ELAQQGSSLAQNRGKLEAQIESLSRENECLRKTNESDsdalRIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQ--EKITE 849
Cdd:pfam17380 286 ERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAE----KARQAEMDRQAAIYAEQERMAMERERELERIRqeERKRE 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 850 IEKCTQEQLDEKSSQLDEvLEKLERHNERK-EKLKQqlkgkevELEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKF 928
Cdd:pfam17380 362 LERIRQEEIAMEISRMRE-LERLQMERQQKnERVRQ-------ELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEAR 433
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 929 ENKEKKLKAERDKSIE-LQKNAMEKLHSMDDAFKRQVDAIVEAHQAEIAQlanEKQKCIDSANLKVhqIEKEMRE----L 1003
Cdd:pfam17380 434 QREVRRLEEERAREMErVRLEEQERQQQVERLRQQEEERKRKKLELEKEK---RDRKRAEEQRRKI--LEKELEErkqaM 508
|
250 260
....*....|....*....|....*..
gi 117414162 1004 LEETCKnKKTMEAKIKQLAFALNEIQQ 1030
Cdd:pfam17380 509 IEEERK-RKLLEKEMEERQKAIYEEER 534
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
424-737 |
9.34e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 40.05 E-value: 9.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 424 QSLVEQLDQEREKRWRAEQAENKLMDYIDELHKHANEKEDihslallttdRLKEIIFRERNSKGQLEvmvhKLQNEIKKL 503
Cdd:TIGR02169 684 EGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEK----------EIEQLEQEEEKLKERLE----ELEEDLSSL 749
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 504 TVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIR-LIQEVELKASAADREIYLLRTSLhREREQA-QQLHQLL 581
Cdd:TIGR02169 750 EQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHsRIPEIQAELSKLEEEVSRIEARL-REIEQKlNRLTLEK 828
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414162 582 ALKEQEHRKELETREFFTD--ADFQDALAKEIAKEEKKhEQMIKEYQEKIDVLSQQYMDLENEfrialtvearrfqdvkd 659
Cdd:TIGR02169 829 EYLEKEIQELQEQRIDLKEqiKSIEKEIENLNGKKEEL-EEELEELEAALRDLESRLGDLKKE----------------- 890
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 117414162 660 gFENVATELAKskhaliwAQRKENESSSLIKDLTCMVKEQKTKLAEV-SKLKQETAANLQNQINTLEILIEDDKQKSIQ 737
Cdd:TIGR02169 891 -RDELEAQLRE-------LERKIEELEAQIEKKRKRLSELKAKLEALeEELSEIEDPKGEDEEIPEEELSLEDVQAELQ 961
|
|
| |
