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Conserved domains on  [gi|15240234|ref|NP_201519|]
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target of early activation tagged (EAT) 3 [Arabidopsis thaliana]

Protein Classification

AP2/ERF family transcription factor( domain architecture ID 10889857)

AP2/ERF family transcription factor binds to the GCC-box pathogenesis-related promoter element; similar to Oryza sativa APETALA2-like proteins which act as transcription factors

CATH:  3.30.730.10
Gene Ontology:  GO:0003700|GO:0006355|GO:0003677
PubMed:  15708341
SCOP:  4000937

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
AP2 smart00380
DNA-binding domain in plant proteins such as APETALA2 and EREBPs;
188-251 3.74e-26

DNA-binding domain in plant proteins such as APETALA2 and EREBPs;


:

Pssm-ID: 197689  Cd Length: 64  Bit Score: 98.88  E-value: 3.74e-26
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15240234    188 KYRGVTLHKCGRWESRLGQFLNKKYVYLGLFDTEIEAARAYDKAAIKCNGKDAVTNFDPKVYEE 251
Cdd:smart00380   1 KYRGVRQRPWGKWVAEIRDPSKGKRVWLGTFDTAEEAARAYDRAAFKFRGRSARLNFPNSLYDS 64
AP2 super family cl00033
DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP ...
96-156 3.36e-13

DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP (ethylene responsive element binding protein). In EREBPs the domain specifically binds to the 11bp GCC box of the ethylene response element (ERE), a promotor element essential for ethylene responsiveness. EREBPs and the C-repeat binding factor CBF1, which is involved in stress response, contain a single copy of the AP2 domain. APETALA2-like proteins, which play a role in plant development contain two copies.


The actual alignment was detected with superfamily member smart00380:

Pssm-ID: 444663  Cd Length: 64  Bit Score: 63.82  E-value: 3.36e-13
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15240234     96 QYRGVTFyRRTGRWESHIWD--CGKQVYLGGFDTAHAAARAYDRAAIKFRGVDADINFDIEDY 156
Cdd:smart00380   1 KYRGVRQ-RPWGKWVAEIRDpsKGKRVWLGTFDTAEEAARAYDRAAFKFRGRSARLNFPNSLY 62
 
Name Accession Description Interval E-value
AP2 smart00380
DNA-binding domain in plant proteins such as APETALA2 and EREBPs;
188-251 3.74e-26

DNA-binding domain in plant proteins such as APETALA2 and EREBPs;


Pssm-ID: 197689  Cd Length: 64  Bit Score: 98.88  E-value: 3.74e-26
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15240234    188 KYRGVTLHKCGRWESRLGQFLNKKYVYLGLFDTEIEAARAYDKAAIKCNGKDAVTNFDPKVYEE 251
Cdd:smart00380   1 KYRGVRQRPWGKWVAEIRDPSKGKRVWLGTFDTAEEAARAYDRAAFKFRGRSARLNFPNSLYDS 64
AP2 cd00018
DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP ...
187-245 9.17e-24

DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP (ethylene responsive element binding protein). In EREBPs the domain specifically binds to the 11bp GCC box of the ethylene response element (ERE), a promotor element essential for ethylene responsiveness. EREBPs and the C-repeat binding factor CBF1, which is involved in stress response, contain a single copy of the AP2 domain. APETALA2-like proteins, which play a role in plant development contain two copies.


Pssm-ID: 237985  Cd Length: 61  Bit Score: 92.72  E-value: 9.17e-24
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 15240234 187 SKYRGVTLHKCGRWESRLGQFLNKKYVYLGLFDTEIEAARAYDKAAIKCNGKDAVTNFD 245
Cdd:cd00018   1 SKYRGVRQRPWGKWVAEIRDPSGGRRIWLGTFDTAEEAARAYDRAALKLRGSSAVLNFP 59
AP2 smart00380
DNA-binding domain in plant proteins such as APETALA2 and EREBPs;
96-156 3.36e-13

DNA-binding domain in plant proteins such as APETALA2 and EREBPs;


Pssm-ID: 197689  Cd Length: 64  Bit Score: 63.82  E-value: 3.36e-13
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15240234     96 QYRGVTFyRRTGRWESHIWD--CGKQVYLGGFDTAHAAARAYDRAAIKFRGVDADINFDIEDY 156
Cdd:smart00380   1 KYRGVRQ-RPWGKWVAEIRDpsKGKRVWLGTFDTAEEAARAYDRAAFKFRGRSARLNFPNSLY 62
AP2 cd00018
DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP ...
96-153 5.72e-11

DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP (ethylene responsive element binding protein). In EREBPs the domain specifically binds to the 11bp GCC box of the ethylene response element (ERE), a promotor element essential for ethylene responsiveness. EREBPs and the C-repeat binding factor CBF1, which is involved in stress response, contain a single copy of the AP2 domain. APETALA2-like proteins, which play a role in plant development contain two copies.


Pssm-ID: 237985  Cd Length: 61  Bit Score: 57.28  E-value: 5.72e-11
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15240234  96 QYRGVTFyRRTGRWESHIWDC--GKQVYLGGFDTAHAAARAYDRAAIKFRGVDADINFDI 153
Cdd:cd00018   2 KYRGVRQ-RPWGKWVAEIRDPsgGRRIWLGTFDTAEEAARAYDRAALKLRGSSAVLNFPD 60
AP2 pfam00847
AP2 domain; This 60 amino acid residue domain can bind to DNA and is found in transcription ...
188-234 3.27e-05

AP2 domain; This 60 amino acid residue domain can bind to DNA and is found in transcription factor proteins.


Pssm-ID: 425904  Cd Length: 52  Bit Score: 41.08  E-value: 3.27e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 15240234   188 KYRGVTLHKC-GRW--ESRLGQFLNKKYVYLGLFDTEiEAARAYDKAAIK 234
Cdd:pfam00847   1 KIRGVRYDKKwGRWvaEWSENGKRRKKRFSLGKYGTE-EAKRAAIEARKK 49
 
Name Accession Description Interval E-value
AP2 smart00380
DNA-binding domain in plant proteins such as APETALA2 and EREBPs;
188-251 3.74e-26

DNA-binding domain in plant proteins such as APETALA2 and EREBPs;


Pssm-ID: 197689  Cd Length: 64  Bit Score: 98.88  E-value: 3.74e-26
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15240234    188 KYRGVTLHKCGRWESRLGQFLNKKYVYLGLFDTEIEAARAYDKAAIKCNGKDAVTNFDPKVYEE 251
Cdd:smart00380   1 KYRGVRQRPWGKWVAEIRDPSKGKRVWLGTFDTAEEAARAYDRAAFKFRGRSARLNFPNSLYDS 64
AP2 cd00018
DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP ...
187-245 9.17e-24

DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP (ethylene responsive element binding protein). In EREBPs the domain specifically binds to the 11bp GCC box of the ethylene response element (ERE), a promotor element essential for ethylene responsiveness. EREBPs and the C-repeat binding factor CBF1, which is involved in stress response, contain a single copy of the AP2 domain. APETALA2-like proteins, which play a role in plant development contain two copies.


Pssm-ID: 237985  Cd Length: 61  Bit Score: 92.72  E-value: 9.17e-24
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 15240234 187 SKYRGVTLHKCGRWESRLGQFLNKKYVYLGLFDTEIEAARAYDKAAIKCNGKDAVTNFD 245
Cdd:cd00018   1 SKYRGVRQRPWGKWVAEIRDPSGGRRIWLGTFDTAEEAARAYDRAALKLRGSSAVLNFP 59
AP2 smart00380
DNA-binding domain in plant proteins such as APETALA2 and EREBPs;
96-156 3.36e-13

DNA-binding domain in plant proteins such as APETALA2 and EREBPs;


Pssm-ID: 197689  Cd Length: 64  Bit Score: 63.82  E-value: 3.36e-13
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15240234     96 QYRGVTFyRRTGRWESHIWD--CGKQVYLGGFDTAHAAARAYDRAAIKFRGVDADINFDIEDY 156
Cdd:smart00380   1 KYRGVRQ-RPWGKWVAEIRDpsKGKRVWLGTFDTAEEAARAYDRAAFKFRGRSARLNFPNSLY 62
AP2 cd00018
DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP ...
96-153 5.72e-11

DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP (ethylene responsive element binding protein). In EREBPs the domain specifically binds to the 11bp GCC box of the ethylene response element (ERE), a promotor element essential for ethylene responsiveness. EREBPs and the C-repeat binding factor CBF1, which is involved in stress response, contain a single copy of the AP2 domain. APETALA2-like proteins, which play a role in plant development contain two copies.


Pssm-ID: 237985  Cd Length: 61  Bit Score: 57.28  E-value: 5.72e-11
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15240234  96 QYRGVTFyRRTGRWESHIWDC--GKQVYLGGFDTAHAAARAYDRAAIKFRGVDADINFDI 153
Cdd:cd00018   2 KYRGVRQ-RPWGKWVAEIRDPsgGRRIWLGTFDTAEEAARAYDRAALKLRGSSAVLNFPD 60
AP2 pfam00847
AP2 domain; This 60 amino acid residue domain can bind to DNA and is found in transcription ...
188-234 3.27e-05

AP2 domain; This 60 amino acid residue domain can bind to DNA and is found in transcription factor proteins.


Pssm-ID: 425904  Cd Length: 52  Bit Score: 41.08  E-value: 3.27e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 15240234   188 KYRGVTLHKC-GRW--ESRLGQFLNKKYVYLGLFDTEiEAARAYDKAAIK 234
Cdd:pfam00847   1 KIRGVRYDKKwGRWvaEWSENGKRRKKRFSLGKYGTE-EAKRAAIEARKK 49
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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