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Conserved domains on  [gi|186532794|ref|NP_201396|]
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trafficking protein particle complex subunit-like protein [Arabidopsis thaliana]

Protein Classification

Foie-gras_1 domain-containing protein( domain architecture ID 10570561)

Foie-gras_1 domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Foie-gras_1 pfam11817
Foie gras liver health family 1; Mutating the gene foie gras in zebrafish has been shown to ...
270-539 1.04e-81

Foie gras liver health family 1; Mutating the gene foie gras in zebrafish has been shown to affect development; the mutants develop large, lipid-filled hepatocytes in the liver, resembling those in individuals with fatty liver disease. Foie-gras protein is long and has several well-defined domains though none of them has a known function. We have annotated this one as the first. The C-terminus of this region contains TPR repeats.


:

Pssm-ID: 463359  Cd Length: 248  Bit Score: 267.33  E-value: 1.04e-81
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186532794   270 RLVEIKIIAEQLHFKISTLLLHGGKLIEAVTWFHQHKTSYEKVVGSTEF--IFLHW-DWMSRQFLVFAELLETSSATGQS 346
Cdd:pfam11817    1 RFNEARLLADVIAFKIIRLLLWNGQPSDAVRQFRKHRERVKDVVGRRGKgtAFYGWeAWESRQFSVMAELIREAIIPGLT 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186532794   347 LTSSNqgtaeisltefefYPAYYYQLAAHYLKDKKSALELLLSMSEIaQEIDSSSASITPSVYVGQfaqllekgeaiTLH 426
Cdd:pfam11817   81 PLQTQ-------------HPGYWYQLAARHAMARRSLAEQIPEEDRV-PPGQSPASSLASSFYVYD-----------TYL 135
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186532794   427 SITDEEYTRYTISEAKRVQDSLQIIAWLKRSYESFTNLKAQRMAALCAFEVAREYFDLADPNNAKFFFDIAANLYRQEGW 506
Cdd:pfam11817  136 APEPHEEYPLSGSEEKGVDHSTLIIALLSRALAEFSKRKQTRMAALLSLEMAEEYLRLGDWAKALELLRPLTLSYRQEGW 215
                          250       260       270
                   ....*....|....*....|....*....|...
gi 186532794   507 VTLLWEVLGYLRECSRNLDALKDFVEFSLEMVA 539
Cdd:pfam11817  216 WTLLEEVLWALRECALLVGDVKDVLAVDWELLS 248
 
Name Accession Description Interval E-value
Foie-gras_1 pfam11817
Foie gras liver health family 1; Mutating the gene foie gras in zebrafish has been shown to ...
270-539 1.04e-81

Foie gras liver health family 1; Mutating the gene foie gras in zebrafish has been shown to affect development; the mutants develop large, lipid-filled hepatocytes in the liver, resembling those in individuals with fatty liver disease. Foie-gras protein is long and has several well-defined domains though none of them has a known function. We have annotated this one as the first. The C-terminus of this region contains TPR repeats.


Pssm-ID: 463359  Cd Length: 248  Bit Score: 267.33  E-value: 1.04e-81
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186532794   270 RLVEIKIIAEQLHFKISTLLLHGGKLIEAVTWFHQHKTSYEKVVGSTEF--IFLHW-DWMSRQFLVFAELLETSSATGQS 346
Cdd:pfam11817    1 RFNEARLLADVIAFKIIRLLLWNGQPSDAVRQFRKHRERVKDVVGRRGKgtAFYGWeAWESRQFSVMAELIREAIIPGLT 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186532794   347 LTSSNqgtaeisltefefYPAYYYQLAAHYLKDKKSALELLLSMSEIaQEIDSSSASITPSVYVGQfaqllekgeaiTLH 426
Cdd:pfam11817   81 PLQTQ-------------HPGYWYQLAARHAMARRSLAEQIPEEDRV-PPGQSPASSLASSFYVYD-----------TYL 135
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186532794   427 SITDEEYTRYTISEAKRVQDSLQIIAWLKRSYESFTNLKAQRMAALCAFEVAREYFDLADPNNAKFFFDIAANLYRQEGW 506
Cdd:pfam11817  136 APEPHEEYPLSGSEEKGVDHSTLIIALLSRALAEFSKRKQTRMAALLSLEMAEEYLRLGDWAKALELLRPLTLSYRQEGW 215
                          250       260       270
                   ....*....|....*....|....*....|...
gi 186532794   507 VTLLWEVLGYLRECSRNLDALKDFVEFSLEMVA 539
Cdd:pfam11817  216 WTLLEEVLWALRECALLVGDVKDVLAVDWELLS 248
 
Name Accession Description Interval E-value
Foie-gras_1 pfam11817
Foie gras liver health family 1; Mutating the gene foie gras in zebrafish has been shown to ...
270-539 1.04e-81

Foie gras liver health family 1; Mutating the gene foie gras in zebrafish has been shown to affect development; the mutants develop large, lipid-filled hepatocytes in the liver, resembling those in individuals with fatty liver disease. Foie-gras protein is long and has several well-defined domains though none of them has a known function. We have annotated this one as the first. The C-terminus of this region contains TPR repeats.


Pssm-ID: 463359  Cd Length: 248  Bit Score: 267.33  E-value: 1.04e-81
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186532794   270 RLVEIKIIAEQLHFKISTLLLHGGKLIEAVTWFHQHKTSYEKVVGSTEF--IFLHW-DWMSRQFLVFAELLETSSATGQS 346
Cdd:pfam11817    1 RFNEARLLADVIAFKIIRLLLWNGQPSDAVRQFRKHRERVKDVVGRRGKgtAFYGWeAWESRQFSVMAELIREAIIPGLT 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186532794   347 LTSSNqgtaeisltefefYPAYYYQLAAHYLKDKKSALELLLSMSEIaQEIDSSSASITPSVYVGQfaqllekgeaiTLH 426
Cdd:pfam11817   81 PLQTQ-------------HPGYWYQLAARHAMARRSLAEQIPEEDRV-PPGQSPASSLASSFYVYD-----------TYL 135
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186532794   427 SITDEEYTRYTISEAKRVQDSLQIIAWLKRSYESFTNLKAQRMAALCAFEVAREYFDLADPNNAKFFFDIAANLYRQEGW 506
Cdd:pfam11817  136 APEPHEEYPLSGSEEKGVDHSTLIIALLSRALAEFSKRKQTRMAALLSLEMAEEYLRLGDWAKALELLRPLTLSYRQEGW 215
                          250       260       270
                   ....*....|....*....|....*....|...
gi 186532794   507 VTLLWEVLGYLRECSRNLDALKDFVEFSLEMVA 539
Cdd:pfam11817  216 WTLLEEVLWALRECALLVGDVKDVLAVDWELLS 248
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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