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Conserved domains on  [gi|240256469|ref|NP_200917|]
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Polynucleotidyl transferase, ribonuclease H-like superfamily protein [Arabidopsis thaliana]

Protein Classification

ribonuclease H family protein( domain architecture ID 10153149)

ribonuclease H (RNaseH) family protein containing a reverse transcriptase (RT)-like domain; may be an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner

CATH:  3.30.420.10
EC:  3.1.26.4
Gene Ontology:  GO:0003723|GO:0004540
PubMed:  16093691
SCOP:  4000541

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RNase_H_like cd06222
Ribonuclease H-like superfamily, including RNase H, HI, HII, HIII, and RNase-like domain IV of ...
 522-626 9.31e-20

Ribonuclease H-like superfamily, including RNase H, HI, HII, HIII, and RNase-like domain IV of spliceosomal protein Prp8; Ribonuclease H (RNase H) enzymes are divided into two major families, Type 1 and Type 2, based on amino acid sequence similarities and biochemical properties. RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner in the presence of divalent cations. It is widely present in various organisms, including bacteria, archaea, and eukaryotes. Most prokaryotic and eukaryotic genomes contain multiple RNase H genes. Despite the lack of amino acid sequence homology, type 1 and type 2 RNase H share a main-chain fold and steric configurations of the four acidic active-site residues and have the same catalytic mechanism and functions in cells. RNase H is involved in DNA replication, repair and transcription. An important RNase H function is to remove Okazaki fragments during DNA replication. RNase H inhibitors have been explored as anti-HIV drug targets since RNase H inactivation inhibits reverse transcription. This model also includes the Prp8 domain IV, which adopts the RNase fold but shows low sequence homology; domain IV is implicated in key spliceosomal interactions.


:

Pssm-ID: 259998 [Multi-domain]  Cd Length: 121  Bit Score: 85.44  E-value: 9.31e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469 522 AGIVRDQSGKWVFGYiRCHKSIPEVV-AGLLAIYQGLKYLWDSGFRRIHLETTSFEIINALTTKSSLFCKSKTLLGACKD 600
Cdd:cd06222   17 GGVLRDHEGGWLGGF-ALKIGAPTALeAELLALLLALELALDLGYLKVIIESDSKYVVDLINSGSFKWSPNILLIEDILL 95

                         90       100
                 ....*....|....*....|....*.
gi 240256469 601 MILKEWECDIYHISKEQNSCAEWLAK 626
Cdd:cd06222   96 LLSRFWSVKISHVPREGNQVADALAK 121
PRK12323 super family cl46901
DNA polymerase III subunit gamma/tau;
48-196 7.04e-10

DNA polymerase III subunit gamma/tau;


The actual alignment was detected with superfamily member PRK14951:

Pssm-ID: 481241 [Multi-domain]  Cd Length: 618  Bit Score: 62.04  E-value: 7.04e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  48 AMKLTSGGNGVAV---SPVKPARATSQVPKRVPPSRTPEAPRSVPACPIPEIPRPVPARPTPETPRPVTARPTPEIPRPV 124
Cdd:PRK14951 363 AFKPAAAAEAAAPaekKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAP 442

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 240256469 125 PARPISEVQTLVPTRPTSTAPSPVSAHP-TSVVPSPVSVHPTSVAPSPVSACLTSEASKPVL--ANPAAGIRREL 196
Cdd:PRK14951 443 AAVALAPAPPAQAAPETVAIPVRVAPEPaVASAAPAPAAAPAAARLTPTEEGDVWHATVQQLaaAEAITALAREL 517
 
Name Accession Description Interval E-value
RNase_H_like cd06222
Ribonuclease H-like superfamily, including RNase H, HI, HII, HIII, and RNase-like domain IV of ...
 522-626 9.31e-20

Ribonuclease H-like superfamily, including RNase H, HI, HII, HIII, and RNase-like domain IV of spliceosomal protein Prp8; Ribonuclease H (RNase H) enzymes are divided into two major families, Type 1 and Type 2, based on amino acid sequence similarities and biochemical properties. RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner in the presence of divalent cations. It is widely present in various organisms, including bacteria, archaea, and eukaryotes. Most prokaryotic and eukaryotic genomes contain multiple RNase H genes. Despite the lack of amino acid sequence homology, type 1 and type 2 RNase H share a main-chain fold and steric configurations of the four acidic active-site residues and have the same catalytic mechanism and functions in cells. RNase H is involved in DNA replication, repair and transcription. An important RNase H function is to remove Okazaki fragments during DNA replication. RNase H inhibitors have been explored as anti-HIV drug targets since RNase H inactivation inhibits reverse transcription. This model also includes the Prp8 domain IV, which adopts the RNase fold but shows low sequence homology; domain IV is implicated in key spliceosomal interactions.


Pssm-ID: 259998 [Multi-domain]  Cd Length: 121  Bit Score: 85.44  E-value: 9.31e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469 522 AGIVRDQSGKWVFGYiRCHKSIPEVV-AGLLAIYQGLKYLWDSGFRRIHLETTSFEIINALTTKSSLFCKSKTLLGACKD 600
Cdd:cd06222   17 GGVLRDHEGGWLGGF-ALKIGAPTALeAELLALLLALELALDLGYLKVIIESDSKYVVDLINSGSFKWSPNILLIEDILL 95

                         90       100
                 ....*....|....*....|....*.
gi 240256469 601 MILKEWECDIYHISKEQNSCAEWLAK 626
Cdd:cd06222   96 LLSRFWSVKISHVPREGNQVADALAK 121
RVT_3 pfam13456
Reverse transcriptase-like; This domain is found in plants and appears to be part of a ...
 507-628 1.73e-17

Reverse transcriptase-like; This domain is found in plants and appears to be part of a retrotransposon.


Pssm-ID: 433223 [Multi-domain]  Cd Length: 123  Bit Score: 78.85  E-value: 1.73e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  507 NIQGTSNPLSDLTRSAGIVRDQSGKWVFGY-IRCHKSIPEVVAGLLAIYQGLKYLWDSGFRRIHLETTSFEIINALTTKS 585
Cdd:pfam13456   1 NFDGAFKCDSGLAGAGVVIRDPNGNVLLAGqKKLGPGASVLEAEAQALIIGLQLAWKLGIRHLIVEGDSATVVQLINGRS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 240256469  586 SLFCKSKTLLGACKDMILKEWECDIYHISKEQNSCAEWLAKRS 628
Cdd:pfam13456  81 PKQSKLANLLDEIRKLLKRFESVSFEHIPREQNRVADTLAKMA 123
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 48-196 7.04e-10

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 62.04  E-value: 7.04e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  48 AMKLTSGGNGVAV---SPVKPARATSQVPKRVPPSRTPEAPRSVPACPIPEIPRPVPARPTPETPRPVTARPTPEIPRPV 124
Cdd:PRK14951 363 AFKPAAAAEAAAPaekKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAP 442

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 240256469 125 PARPISEVQTLVPTRPTSTAPSPVSAHP-TSVVPSPVSVHPTSVAPSPVSACLTSEASKPVL--ANPAAGIRREL 196
Cdd:PRK14951 443 AAVALAPAPPAQAAPETVAIPVRVAPEPaVASAAPAPAAAPAAARLTPTEEGDVWHATVQQLaaAEAITALAREL 517
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 78-218 3.38e-06

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 50.30  E-value: 3.38e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   78 PSRTpEAPRSVPAcPIPEIPRPVPARPTPETPRPVTARPTPEIPRPVPARPISEVQTLVPTRPTS--TAPSPVSAHPTSV 155
Cdd:pfam05109 449 PSST-HVPTNLTA-PASTGPTVSTADVTSPTPAGTTSGASPVTPSPSPRDNGTESKAPDMTSPTSavTTPTPNATSPTPA 526

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 240256469  156 V--PSPVSVHPTSVAPSPVSACLT----SEASKPVLANPAAGIRRELVCSLRALSMTTTPVRQRTTPSL 218
Cdd:pfam05109 527 VttPTPNATSPTLGKTSPTSAVTTptpnATSPTPAVTTPTPNATIPTLGKTSPTSAVTTPTPNATSPTV 595
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
 62-194 2.26e-03

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 40.52  E-value: 2.26e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  62 PVKPARATSQVPKRVPPSRTPEAPRSVPACPIPEIPRPVPARPTPETPRPVT----ARPTPEIPRPVPARPISEVQTLVP 137
Cdd:NF040712 192 FGRPLRPLATVPRLAREPADARPEEVEPAPAAEGAPATDSDPAEAGTPDDLAsarrRRAGVEQPEDEPVGPGAAPAAEPD 271

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 240256469 138 TRPTSTAPSPVSAHPtsvvPSPVSVHPTSVAPSPVSACLTSEASKPVLANPAAGIRR 194
Cdd:NF040712 272 EATRDAGEPPAPGAA----ETPEAAEPPAPAPAAPAAPAAPEAEEPARPEPPPAPKP 324
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 7-171 7.03e-03

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 39.37  E-value: 7.03e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   7 PSDSIKVVPGRSKLRV--ESSNPVARGNPTPRASKvkllsPEEAMKLTSGGNGVAVSPVKPARATSQVPKRVPPSRTPEA 84
Cdd:NF033839 328 PKPEVKPQPEKPKPEVkpQLETPKPEVKPQPEKPK-----PEVKPQPEKPKPEVKPQPETPKPEVKPQPEKPKPEVKPQP 402

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  85 PRSVPAC-PIPEIPRPvPARPTPETPRPvTARPTPEIP----RPVPARPISEVQTLVPTRPTSTAPSPVSAHPtSVVPSP 159
Cdd:NF033839 403 EKPKPEVkPQPEKPKP-EVKPQPEKPKP-EVKPQPEKPkpevKPQPEKPKPEVKPQPETPKPEVKPQPEKPKP-EVKPQP 479

                        170
                 ....*....|..
gi 240256469 160 VSVHPTSVAPSP 171
Cdd:NF033839 480 EKPKPDNSKPQA 491
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
 27-158 7.11e-03

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 38.98  E-value: 7.11e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  27 PVARGNPTPRASKVKLLSPEEAMKLTSGGNGVAVSPVKPARATSQVPKRVPPSRTPEAPRSVPACPIPEIPRPVPARPTP 106
Cdd:NF040712 201 TVPRLAREPADARPEEVEPAPAAEGAPATDSDPAEAGTPDDLASARRRRAGVEQPEDEPVGPGAAPAAEPDEATRDAGEP 280

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 240256469 107 ETPRPVTARPTPEIPRPVPARPISevqtlvPTRPTSTAPSPVSAHPTS---------VVPS 158
Cdd:NF040712 281 PAPGAAETPEAAEPPAPAPAAPAA------PAAPEAEEPARPEPPPAPkpkrrrrraSVPS 335
 
Name Accession Description Interval E-value
RNase_H_like cd06222
Ribonuclease H-like superfamily, including RNase H, HI, HII, HIII, and RNase-like domain IV of ...
 522-626 9.31e-20

Ribonuclease H-like superfamily, including RNase H, HI, HII, HIII, and RNase-like domain IV of spliceosomal protein Prp8; Ribonuclease H (RNase H) enzymes are divided into two major families, Type 1 and Type 2, based on amino acid sequence similarities and biochemical properties. RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner in the presence of divalent cations. It is widely present in various organisms, including bacteria, archaea, and eukaryotes. Most prokaryotic and eukaryotic genomes contain multiple RNase H genes. Despite the lack of amino acid sequence homology, type 1 and type 2 RNase H share a main-chain fold and steric configurations of the four acidic active-site residues and have the same catalytic mechanism and functions in cells. RNase H is involved in DNA replication, repair and transcription. An important RNase H function is to remove Okazaki fragments during DNA replication. RNase H inhibitors have been explored as anti-HIV drug targets since RNase H inactivation inhibits reverse transcription. This model also includes the Prp8 domain IV, which adopts the RNase fold but shows low sequence homology; domain IV is implicated in key spliceosomal interactions.


Pssm-ID: 259998 [Multi-domain]  Cd Length: 121  Bit Score: 85.44  E-value: 9.31e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469 522 AGIVRDQSGKWVFGYiRCHKSIPEVV-AGLLAIYQGLKYLWDSGFRRIHLETTSFEIINALTTKSSLFCKSKTLLGACKD 600
Cdd:cd06222   17 GGVLRDHEGGWLGGF-ALKIGAPTALeAELLALLLALELALDLGYLKVIIESDSKYVVDLINSGSFKWSPNILLIEDILL 95

                         90       100
                 ....*....|....*....|....*.
gi 240256469 601 MILKEWECDIYHISKEQNSCAEWLAK 626
Cdd:cd06222   96 LLSRFWSVKISHVPREGNQVADALAK 121
RVT_3 pfam13456
Reverse transcriptase-like; This domain is found in plants and appears to be part of a ...
 507-628 1.73e-17

Reverse transcriptase-like; This domain is found in plants and appears to be part of a retrotransposon.


Pssm-ID: 433223 [Multi-domain]  Cd Length: 123  Bit Score: 78.85  E-value: 1.73e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  507 NIQGTSNPLSDLTRSAGIVRDQSGKWVFGY-IRCHKSIPEVVAGLLAIYQGLKYLWDSGFRRIHLETTSFEIINALTTKS 585
Cdd:pfam13456   1 NFDGAFKCDSGLAGAGVVIRDPNGNVLLAGqKKLGPGASVLEAEAQALIIGLQLAWKLGIRHLIVEGDSATVVQLINGRS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 240256469  586 SLFCKSKTLLGACKDMILKEWECDIYHISKEQNSCAEWLAKRS 628
Cdd:pfam13456  81 PKQSKLANLLDEIRKLLKRFESVSFEHIPREQNRVADTLAKMA 123
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 48-196 7.04e-10

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 62.04  E-value: 7.04e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  48 AMKLTSGGNGVAV---SPVKPARATSQVPKRVPPSRTPEAPRSVPACPIPEIPRPVPARPTPETPRPVTARPTPEIPRPV 124
Cdd:PRK14951 363 AFKPAAAAEAAAPaekKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAP 442

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 240256469 125 PARPISEVQTLVPTRPTSTAPSPVSAHP-TSVVPSPVSVHPTSVAPSPVSACLTSEASKPVL--ANPAAGIRREL 196
Cdd:PRK14951 443 AAVALAPAPPAQAAPETVAIPVRVAPEPaVASAAPAPAAAPAAARLTPTEEGDVWHATVQQLaaAEAITALAREL 517
PHA03247 PHA03247
large tegument protein UL36; Provisional
 2-261 9.64e-10

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 62.26  E-value: 9.64e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469    2 SPGQLPSDSIKvvPGRSKLRVESSNPVARGNPTPRASKVKLLSPEEAMKLTSGGNgvaVSPVKPARATSQVPKRVPPSRT 81
Cdd:PHA03247 2608 PRGPAPPSPLP--PDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGR---VSRPRRARRLGRAAQASSPPQR 2682

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   82 PEAPRSVPAC-PIPEIPRPVPARPTPETPRPVTARPTPEIPRPVPARPISEVQTLVPTRPTSTAPSPVSAHPTSVVPSPV 160
Cdd:PHA03247 2683 PRRRAARPTVgSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPT 2762

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  161 SVHPTSVAPsPVSACLTSEASKPVLANPAAGIRRELVCSLRALSMTTTPVRQRTT--PSLLKSKKVEPPSPRALQIRSRV 238
Cdd:PHA03247 2763 TAGPPAPAP-PAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAalPPAASPAGPLPPPTSAQPTAPPP 2841

                         250       260
                  ....*....|....*....|...
gi 240256469  239 KQQAANATKIQQGAIVEVGDKAK 261
Cdd:PHA03247 2842 PPGPPPPSLPLGGSVAPGGDVRR 2864
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 20-164 1.56e-08

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 57.80  E-value: 1.56e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  20 LRVESSNPVARGNPTPRASKVKLLSPEEAMkltsggngVAVSPVkPARATSQVPKRVPPSRTPEAPRSVPACPIPEIPRP 99
Cdd:PRK14951 359 LRLLAFKPAAAAEAAAPAEKKTPARPEAAA--------PAAAPV-AQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAP 429

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 240256469 100 VPARPTPETPRPVTARPTPEIPRPVPARPISEVQTLVPTRP-TSTAPSPVSAHPTSVVPSPVSVHP 164
Cdd:PRK14951 430 AAAAPAAAPAAAPAAVALAPAPPAQAAPETVAIPVRVAPEPaVASAAPAPAAAPAAARLTPTEEGD 495
PHA03247 PHA03247
large tegument protein UL36; Provisional
 7-209 1.68e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 58.03  E-value: 1.68e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469    7 PSDSIKVVPGRSKLRVESSNPVARGNPTPRASKVKLLSPEE--AMKLTSGGNGVAVSPVK---PARATSQVP-------- 73
Cdd:PHA03247 2804 PADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGppPPSLPLGGSVAPGGDVRrrpPSRSPAAKPaaparppv 2883

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   74 ---KRVPPSRTPEaPRSVPACPIPEIPRP-VPARPTPETPRPVTARPTPeiPRPVPARPISEVQtlvPTRPTSTAPSPVS 149
Cdd:PHA03247 2884 rrlARPAVSRSTE-SFALPPDQPERPPQPqAPPPPQPQPQPPPPPQPQP--PPPPPPRPQPPLA---PTTDPAGAGEPSG 2957

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 240256469  150 AHPT----SVVPSPVSVhPTSVAPSPVSACLTSEASKPVLANPAAGIRRELVCSLrALSMTTTP 209
Cdd:PHA03247 2958 AVPQpwlgALVPGRVAV-PRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSL-ALHEETDP 3019
PHA03247 PHA03247
large tegument protein UL36; Provisional
 27-231 2.03e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 58.03  E-value: 2.03e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   27 PVARGNPTPRASKVKLLSPEEAMKLTSGGNGVAVSPVKPARATSQVPKRVPPSRTPEAPRSVPACPI-PEIPRPVPARPT 105
Cdd:PHA03247 2683 PRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPAtPGGPARPARPPT 2762

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  106 PETPrPVTARPTPEIPRPVPARPISEVQTLVPTRPTSTAPSPVSAHPtSVVPSPVSVHPTSVAPSPVSACLTSeaSKPVL 185
Cdd:PHA03247 2763 TAGP-PAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPP-AAVLAPAAALPPAASPAGPLPPPTS--AQPTA 2838

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 240256469  186 ANPAAGIRRELVcSLRALSMTTTPVRQRTTPSLLKSKKVEPPSPRA 231
Cdd:PHA03247 2839 PPPPPGPPPPSL-PLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPV 2883
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 68-194 4.29e-08

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 56.53  E-value: 4.29e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  68 ATSQVPKRVPPSRTPEAPRSVPACPIPEIPRPVPARPTPETPRPVTARPTPEIPRPVPARPiSEVQTLVPTRPTSTAPSP 147
Cdd:PRK07764 394 PAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAP-SPPPAAAPSAQPAPAPAA 472

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 240256469 148 VSAHPTSVVPSPVSVHPTSVAPSPvsaclTSEASKPVLANPAAGIRR 194
Cdd:PRK07764 473 APEPTAAPAPAPPAAPAPAAAPAA-----PAAPAAPAGADDAATLRE 514
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 58-147 4.54e-08

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 56.36  E-value: 4.54e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  58 VAVSPVKPARATSQVPKRVPPSRTP-EAPRSVPACPIPEIPrPVPARPTPETPRP-VTARPTPEIPRPVPARPISEVQtl 135
Cdd:PRK14950 361 VPVPAPQPAKPTAAAPSPVRPTPAPsTRPKAAAAANIPPKE-PVRETATPPPVPPrPVAPPVPHTPESAPKLTRAAIP-- 437

                         90
                 ....*....|..
gi 240256469 136 VPTRPTSTAPSP 147
Cdd:PRK14950 438 VDEKPKYTPPAP 449
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 57-251 1.60e-06

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 51.40  E-value: 1.60e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  57 GVAVSPVKPARATSQVPKRVPPSRTPEAPRSVPACPIPEIPRPVP-ARPTPETPRPVTARPTPEIPRPVPARPISEVQtl 135
Cdd:PRK07994 379 ASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLaARQQLQRAQGATKAKKSEPAAASRARPVNSAL-- 456

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469 136 vpTRPTSTAPSPVSAHPTSVVPSPVSVHPTSVAPSPVSACLTSEASKPVLANPAAGirrELVCSLRALSMTTTP----VR 211
Cdd:PRK07994 457 --ERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKALKKALEHEKTP---ELAAKLAAEAIERDPwaalVS 531

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 240256469 212 QRTTPSLlkskkveppspralqirsrVKQQAANATKIQQG 251
Cdd:PRK07994 532 QLGLPGL-------------------VEQLALNAWKEEHD 552
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 84-171 2.16e-06

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 50.96  E-value: 2.16e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  84 APRSVPACPIPEIPRPVPARPTPETPRPVTARPTPEIPrPVPARPISEVQTLVPTRPTSTAPSPV--SAHPTSVVPSPVS 161
Cdd:PRK14950 361 VPVPAPQPAKPTAAAPSPVRPTPAPSTRPKAAAAANIP-PKEPVRETATPPPVPPRPVAPPVPHTpeSAPKLTRAAIPVD 439

                         90
                 ....*....|
gi 240256469 162 VHPTSVAPSP 171
Cdd:PRK14950 440 EKPKYTPPAP 449
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 64-282 2.35e-06

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 51.24  E-value: 2.35e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   64 KPARATSQVPKRVPPSRTPEAPRSV--PACPIPE-IPRPVPARPTPETPRPVTARPTPEIPRPVPARP----ISEV---- 132
Cdd:PRK10263  437 APEQPVAGNAWQAEEQQSTFAPQSTyqTEQTYQQpAAQEPLYQQPQPVEQQPVVEPEPVVEETKPARPplyyFEEVeekr 516

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  133 -----QTLVPTRPT-STAPSPVSAHPTSVVPSPVSVHPtsVAPSPVSACLTSEASKPVLANPAAGIRRELVCSLRALSMT 206
Cdd:PRK10263  517 arereQLAAWYQPIpEPVKEPEPIKSSLKAPSVAAVPP--VEAAAAVSPLASGVKKATLATGAAATVAAPVFSLANSGGP 594

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 240256469  207 TTPVRQRTTPSLLKSKKVEPPSPRALqirsrvkqqAANATKIQQGAIVEVGDKAKDHGSNEIRRSVSEEELSELLQ 282
Cdd:PRK10263  595 RPQVKEGIGPQLPRPKRIRVPTRREL---------ASYGIKLPSQRAAEEKAREAQRNQYDSGDQYNDDEIDAMQQ 661
PHA03247 PHA03247
large tegument protein UL36; Provisional
 25-232 2.80e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 51.09  E-value: 2.80e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   25 SNPVARGNPTPRASKVKLLSPEEAMKLTSGGNGVAVSPVKPARATSQVPKRVPPSRTPEAPRSVPACPIPEIPRPVPARP 104
Cdd:PHA03247 2794 SRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAA 2873

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  105 TPETP---------RPVTARPTPEIPRPvPARPISEVQTLVPTRPTSTAPSPVSAHPTSVVPSPvsvhPTSVAPSPVSAc 175
Cdd:PHA03247 2874 KPAAParppvrrlaRPAVSRSTESFALP-PDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPP----PRPQPPLAPTT- 2947

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 240256469  176 LTSEASKPVLANPAAgirrelvcSLRALSMTTTPVRQRTTPSLLKSKKVEPPSPRAL 232
Cdd:PHA03247 2948 DPAGAGEPSGAVPQP--------WLGALVPGRVAVPRFRVPQPAPSREAPASSTPPL 2996
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 78-218 3.38e-06

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 50.30  E-value: 3.38e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   78 PSRTpEAPRSVPAcPIPEIPRPVPARPTPETPRPVTARPTPEIPRPVPARPISEVQTLVPTRPTS--TAPSPVSAHPTSV 155
Cdd:pfam05109 449 PSST-HVPTNLTA-PASTGPTVSTADVTSPTPAGTTSGASPVTPSPSPRDNGTESKAPDMTSPTSavTTPTPNATSPTPA 526

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 240256469  156 V--PSPVSVHPTSVAPSPVSACLT----SEASKPVLANPAAGIRRELVCSLRALSMTTTPVRQRTTPSL 218
Cdd:pfam05109 527 VttPTPNATSPTLGKTSPTSAVTTptpnATSPTPAVTTPTPNATIPTLGKTSPTSAVTTPTPNATSPTV 595
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 63-235 3.88e-06

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 50.30  E-value: 3.88e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   63 VKPARATSQVPKRVPPSRTPEAPRSVP-----ACPIPEIPRPVPA--RPTPETPRPVTARPTPEiprpvparPISEVQTL 135
Cdd:pfam05109 468 VSTADVTSPTPAGTTSGASPVTPSPSPrdngtESKAPDMTSPTSAvtTPTPNATSPTPAVTTPT--------PNATSPTL 539

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  136 VPTRPTS--TAPSPVSAHPTSVV--PSPVSVHPTSVAPSPVSACL--TSEASKPVLA--NPAAGIRRELVCSLRALSMTT 207
Cdd:pfam05109 540 GKTSPTSavTTPTPNATSPTPAVttPTPNATIPTLGKTSPTSAVTtpTPNATSPTVGetSPQANTTNHTLGGTSSTPVVT 619

                         170       180
                  ....*....|....*....|....*...
gi 240256469  208 TPVRQRTTPSLLKSKKVEPPSPRALQIR 235
Cdd:pfam05109 620 SPPKNATSAVTTGQHNITSSSTSSMSLR 647
PRK10819 PRK10819
transport protein TonB; Provisional
 62-158 4.53e-06

transport protein TonB; Provisional


Pssm-ID: 236768 [Multi-domain]  Cd Length: 246  Bit Score: 48.53  E-value: 4.53e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  62 PVKPARATSQVPKRVP-PSRTPEAPRSVPACPIPEIPRPVPaRPTPETPRPVTARPTPEIpRPVPARPISEVQTLVPTRP 140
Cdd:PRK10819  63 AVQPPPEPVVEPEPEPePIPEPPKEAPVVIPKPEPKPKPKP-KPKPKPVKKVEEQPKREV-KPVEPRPASPFENTAPARP 140

                         90
                 ....*....|....*...
gi 240256469 141 TSTAPSPVSAHPTSVVPS 158
Cdd:PRK10819 141 TSSTATAAASKPVTSVSS 158
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
22-252 5.53e-06

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 49.85  E-value: 5.53e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  22 VESSNPVARGNPTPRASKVKLLSPEEAMKLTSGGNGVAVSP---------------VKPARA------TSQVPKRVPPSR 80
Cdd:PRK07003 372 VPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPkaaaaaaatraeappAAPAPPatadrgDDAADGDAPVPA 451

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  81 TPEAPRSVPACPIPEIPRPVPARPTPETPRPVTARPTPEIPRPVPARPISEVQTLVPTRPTSTAPSPVSAHPTSVVPSPV 160
Cdd:PRK07003 452 KANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPE 531

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469 161 SVHPTSVAPSPVSACLTSEASKPVLANpaAGIRRELVCSLRALSMTTTPVRQRTTPSLLKSKKVEP-PSPRALqiRSRVK 239
Cdd:PRK07003 532 ARPPTPAAAAPAARAGGAAAALDVLRN--AGMRVSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQvPTPRAR--AATGD 607

                        250
                 ....*....|...
gi 240256469 240 QQAANATKIQQGA 252
Cdd:PRK07003 608 APPNGAARAEQAA 620
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
52-193 8.42e-06

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 49.08  E-value: 8.42e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  52 TSGGNGVAVSPVKPARA-------------TSQVPKRVPPSRTP-EAPRSVPACPI-PEIPRPVPARPTPETPRPVTARP 116
Cdd:PRK07003 363 TGGGAPGGGVPARVAGAvpapgaraaaavgASAVPAVTAVTGAAgAALAPKAAAAAaATRAEAPPAAPAPPATADRGDDA 442

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 240256469 117 TPeipRPVPARPISEVQTLVPTRPTSTAPSPVSAHPTSVVPSPVSVHPTSVAPSPVSACLTSEASKPV--LANPAAGIR 193
Cdd:PRK07003 443 AD---GDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVpdARAPAAASR 518
PHA03378 PHA03378
EBNA-3B; Provisional
 17-213 1.39e-05

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 48.52  E-value: 1.39e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  17 RSKLRVESSNPVARGNPTPRASKVKLLSPEEAMKLTSGGNGvAVSPVKPARATSQVPKrVPPSRTPEAPRSVPACPIPEI 96
Cdd:PHA03378 543 TEDLDIESDEPASTEPVHDQLLPAPGLGPLQIQPLTSPTTS-QLASSAPSYAQTPWPV-PHPSQTPEPPTTQSHIPETSA 620

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  97 PR--PVPARPTPETP---RPVT----ARPTPEIP---RPVPARPISEVQTLVPTRPTSTAPS---PVSAHPTSVVP---S 158
Cdd:PHA03378 621 PRqwPMPLRPIPMRPlrmQPITfnvlVFPTPHQPpqvEITPYKPTWTQIGHIPYQPSPTGANtmlPIQWAPGTMQPpprA 700

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 240256469 159 PVSVHPTSVAPSPVSACLTSEASKPVLANPAAGIRRELVCSLRALSMTTTPVRQR 213
Cdd:PHA03378 701 PTPMRPPAAPPGRAQRPAAATGRARPPAAAPGRARPPAAAPGRARPPAAAPGRAR 755
PHA02682 PHA02682
ORF080 virion core protein; Provisional
 36-159 2.02e-05

ORF080 virion core protein; Provisional


Pssm-ID: 177464 [Multi-domain]  Cd Length: 280  Bit Score: 46.78  E-value: 2.02e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  36 RASKVKLLSPEEAMKLTSGGNGVAVSPVKPARATsQVPKRVPPSRTPEA--PRSVPACP------------IPEIPRPVP 101
Cdd:PHA02682  60 RYYQSRLKANSACMQRPSGQSPLAPSPACAAPAP-ACPACAPAAPAPAVtcPAPAPACPpataptcpppavCPAPARPAP 138

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469 102 ARPtPETPRPVTARPTPeIPRPVP-ARPISEVQTLVPTR-PTSTAPSPVSAHPTSVVPSP 159
Cdd:PHA02682 139 ACP-PSTRQCPPAPPLP-TPKPAPaAKPIFLHNQLPPPDyPAASCPTIETAPAASPVLEP 196
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 77-197 2.09e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 47.79  E-value: 2.09e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  77 PPSRTPEAPRSVPACPIpeipRPVPARPTPEtprPVTARPTPEIPRPVPARPISEVQTLVPTRPTSTAPSPVSAHPTSVV 156
Cdd:PRK14951 366 PAAAAEAAAPAEKKTPA----RPEAAAPAAA---PVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAP 438

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 240256469 157 PSPVSVHPTSVAPSPVSACLTSEASKPVLANPAAGIRRELV 197
Cdd:PRK14951 439 AAAPAAVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAP 479
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 21-174 2.79e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 47.29  E-value: 2.79e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  21 RVESSNPVARGNPTPRASKvkllspeeamkltSGGNGVAVSPVkPARATSQvPKRVPPSRTPEAPRSVPAcpipeiPRPV 100
Cdd:PRK07764 380 RLERRLGVAGGAGAPAAAA-------------PSAAAAAPAAA-PAPAAAA-PAAAAAPAPAAAPQPAPA------PAPA 438

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 240256469 101 PARPTPETPRPVTARPTPEiPRPVPARPISEVQTLVPTRPTSTAPSPVSAHPTSVVPSPVSVHPTSVAPSPVSA 174
Cdd:PRK07764 439 PAPPSPAGNAPAGGAPSPP-PAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAAT 511
PRK13042 PRK13042
superantigen-like protein SSL4; Reviewed;
57-152 5.21e-05

superantigen-like protein SSL4; Reviewed;


Pssm-ID: 183854 [Multi-domain]  Cd Length: 291  Bit Score: 45.78  E-value: 5.21e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  57 GVAVSPVKPARATsqvpkrVPPSRTPEAPRSVPACPIPEIPRPVPARPTPETPRPVTARPTPEIPRPvparPISEVQTlv 136
Cdd:PRK13042  19 GVITTTTQAANAT------TPSSTKVEAPQSTPPSTKVEAPQSKPNATTPPSTKVEAPQQTPNATTP----SSTKVET-- 86

                         90
                 ....*....|....*.
gi 240256469 137 PTRPTsTAPSPVSAHP 152
Cdd:PRK13042  87 PQSPT-TKQVPTEINP 101
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 107-246 5.31e-05

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 46.45  E-value: 5.31e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  107 ETPRPVTARPTPEI-----PRPVPARPISevqTLVPTR---PTSTAPSPVSAHPTSVVPSPVSVHPTSVAPSPVSACLTS 178
Cdd:pfam05109 423 KAPESTTTSPTLNTtgfaaPNTTTGLPSS---THVPTNltaPASTGPTVSTADVTSPTPAGTTSGASPVTPSPSPRDNGT 499

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 240256469  179 EASKPVLANPAAGIRRELVCSLRALSMTTTPVRQRTTPSLLK---SKKVEPPSPRALQIRSRVKQQAANAT 246
Cdd:pfam05109 500 ESKAPDMTSPTSAVTTPTPNATSPTPAVTTPTPNATSPTLGKtspTSAVTTPTPNATSPTPAVTTPTPNAT 570
PRK04654 PRK04654
sec-independent translocase; Provisional
 97-179 5.56e-05

sec-independent translocase; Provisional


Pssm-ID: 135173 [Multi-domain]  Cd Length: 214  Bit Score: 44.80  E-value: 5.56e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  97 PRPVPArptpetPRPVTARPTPEIPRPVparpisevQTLVPTRPTSTAPSPVSAHPTSVVPSPVSVHP----TSVAPSPV 172
Cdd:PRK04654 139 HTPVPA------PAPVIAQAQPIAPAPH--------QTLVPAPHDTIVPAPHAAHLPSAPATPVSVAPvdagTSASPTPS 204


                 ....*..
gi 240256469 173 SACLTSE 179
Cdd:PRK04654 205 EPTKIQE 211
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
4-218 8.41e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 45.64  E-value: 8.41e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   4 GQLPSDSIKVVPGRSKLRVESSNPVARGNPTPRASKVKLLSPEEAMKLTSGGNGVAVSPVKPARATSQVPKRVPPSRTPE 83
Cdd:PRK12323 370 GGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPA 449

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  84 APRSVPACPIPEIPRPVPARPTPETPRPVTARPTPEIPRPVPARPISEVQTLVPTRPTSTAPSPVSAHPTSVVPSPVSVH 163
Cdd:PRK12323 450 PAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAESIPDP 529

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 240256469 164 PTSVAPSPVSACLTSEASKPVLANPAAGIRRELVCSLRALSMTTTPVRQRTTPSL 218
Cdd:PRK12323 530 ATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDGDWPAL 584
PHA02682 PHA02682
ORF080 virion core protein; Provisional
 67-185 9.01e-05

ORF080 virion core protein; Provisional


Pssm-ID: 177464 [Multi-domain]  Cd Length: 280  Bit Score: 44.85  E-value: 9.01e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  67 RATSQVPKRvPPSRTPEAPRSVPACPIPEIPRPVPARPTPET--PRPVTARPTPEIPRPVPARPISEVQTLVPTRPTSTA 144
Cdd:PHA02682  67 KANSACMQR-PSGQSPLAPSPACAAPAPACPACAPAAPAPAVtcPAPAPACPPATAPTCPPPAVCPAPARPAPACPPSTR 145

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 240256469 145 PSPVSAHPTSVVPSPV---SVHPTSVAPS--PVSACLTSE---ASKPVL 185
Cdd:PHA02682 146 QCPPAPPLPTPKPAPAakpIFLHNQLPPPdyPAASCPTIEtapAASPVL 194
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
43-190 9.01e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 45.64  E-value: 9.01e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  43 LSPEE----AMKL-------TSGGNGVAvSPVKPARATsqVPKRVPPSRTPEAPRSVPACPIPEIPRPVPARPTPETPRP 111
Cdd:PRK12323 345 LAPDEyagfTMTLlrmlafrPGQSGGGA-GPATAAAAP--VAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAA 421

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 240256469 112 VTARPTPEIPRPVPARPISevqtlvpTRPTSTAPSPVSAhptsVVPSPVSVHPTSVAPSPVSAclTSEASKPVLANPAA 190
Cdd:PRK12323 422 APARRSPAPEALAAARQAS-------ARGPGGAPAPAPA----PAAAPAAAARPAAAGPRPVA--AAAAAAPARAAPAA 487
PHA03247 PHA03247
large tegument protein UL36; Provisional
 27-230 1.03e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 45.70  E-value: 1.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   27 PVARGNPTPRASKVKLLSPEEAMKltsggngVAVSPVKParatsqvPKRVPPSRTPEAPRSVPACPIPEIPRPVPARPTP 106
Cdd:PHA03247 2748 PATPGGPARPARPPTTAGPPAPAP-------PAAPAAGP-------PRRLTRPAVASLSESRESLPSPWDPADPPAAVLA 2813

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  107 ETPR-PVTARPTPEIPRPVPARPISEVQTLVPTRPT-----STAP-SPVSAHPTSVVPSPVSVHPTSVAPSPVSACLTSE 179
Cdd:PHA03247 2814 PAAAlPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSlplggSVAPgGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSR 2893

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 240256469  180 ASKPvLANPAAGIRRelvcsLRALSMTTTPVRQRTTPSLLKSKKVEPPSPR 230
Cdd:PHA03247 2894 STES-FALPPDQPER-----PPQPQAPPPPQPQPQPPPPPQPQPPPPPPPR 2938
PHA03369 PHA03369
capsid maturational protease; Provisional
 56-168 1.11e-04

capsid maturational protease; Provisional


Pssm-ID: 223061 [Multi-domain]  Cd Length: 663  Bit Score: 45.38  E-value: 1.11e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  56 NGVAVSPVKPARATSQVPKRVPPSRTP-EAPRSVPACPiPEIPRPVPARPTPETPRPVTARPTPEIPrPVPARPISEVQT 134
Cdd:PHA03369 350 TASLTAPSRVLAAAAKVAVIAAPQTHTgPADRQRPQRP-DGIPYSVPARSPMTAYPPVPQFCGDPGL-VSPYNPQSPGTS 427

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 240256469 135 LVPTRPTSTAPSPVSAH--PTSVVPSPVSVHPTSVA 168
Cdd:PHA03369 428 YGPEPVGPVPPQPTNPYvmPISMANMVYPGHPQEHG 463
PHA03378 PHA03378
EBNA-3B; Provisional
 56-243 1.30e-04

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 45.44  E-value: 1.30e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  56 NGVAVSPVKPARATSQVPKRVP-PSRTPEAPRSVPACPIPEIPRPVPARPTPETPRPVTARPTP-EIPRPVPARPISEVQ 133
Cdd:PHA03378 680 GANTMLPIQWAPGTMQPPPRAPtPMRPPAAPPGRAQRPAAATGRARPPAAAPGRARPPAAAPGRaRPPAAAPGRARPPAA 759

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469 134 TLVPTRPTSTAPSPVSAHPTSVVPsPVSVHPTSVAPSPvsacltseaSKPVLANPAAgirreLVCSLRALSMTTTPVRQR 213
Cdd:PHA03378 760 APGRARPPAAAPGAPTPQPPPQAP-PAPQQRPRGAPTP---------QPPPQAGPTS-----MQLMPRAAPGQQGPTKQI 824

                        170       180       190
                 ....*....|....*....|....*....|
gi 240256469 214 TTPSLLKSKKVEPPSpraLQIRSRVKQQAA 243
Cdd:PHA03378 825 LRQLLTGGVKRGRPS---LKKPAALERQAA 851
PRK10819 PRK10819
transport protein TonB; Provisional
 58-170 1.58e-04

transport protein TonB; Provisional


Pssm-ID: 236768 [Multi-domain]  Cd Length: 246  Bit Score: 43.90  E-value: 1.58e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  58 VAVSPVKPARATSQVPKRVPPSRTPEaPRSVPAcPIPEIPRPVP-ARPTPET-PRPVtARPTPEIPRPVPARPISEVQTL 135
Cdd:PRK10819  48 ISVTMVAPADLEPPQAVQPPPEPVVE-PEPEPE-PIPEPPKEAPvVIPKPEPkPKPK-PKPKPKPVKKVEEQPKREVKPV 124

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 240256469 136 VPtRPTSTAPSPVSAHPTSVVPSPVSVHPTSVAPS 170
Cdd:PRK10819 125 EP-RPASPFENTAPARPTSSTATAAASKPVTSVSS 158
PHA03291 PHA03291
envelope glycoprotein I; Provisional
 62-171 1.75e-04

envelope glycoprotein I; Provisional


Pssm-ID: 223033 [Multi-domain]  Cd Length: 401  Bit Score: 44.56  E-value: 1.75e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  62 PVKPARATSQVPKRVPPSRTPEAPRSVPAcpipEIPRPVPARPTPETPRPVTARPTPEIPRPVPARPISEVQTLVPTRPT 141
Cdd:PHA03291 172 LAAPPLGEGSADGSCDPALPLSAPRLGPA----DVFVPATPRPTPRTTASPETTPTPSTTTSPPSTTIPAPSTTIAAPQA 247

                         90       100       110
                 ....*....|....*....|....*....|
gi 240256469 142 STAPSPvSAHPTSVVPSPVSVHPTSVAPSP 171
Cdd:PHA03291 248 GTTPEA-EGTPAPPTPGGGEAPPANATPAP 276
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 110-252 2.05e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 44.47  E-value: 2.05e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469 110 RPVTARPTPEIPRPVPARPISEVQTLVPTRPTSTAPSPVSAHPTSVVPSPVSVHPTSVAPSPVSACLT-----SEASKPV 184
Cdd:PRK07994 360 HPAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQqlqraQGATKAK 439

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 240256469 185 LANPAAGIRRElvcSLRALSMTTTPVRQRTTPSLLKSKKVEPPSPRALQIRSRVKQQAANATKIQQGA 252
Cdd:PRK07994 440 KSEPAAASRAR---PVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKALKKAL 504
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 2-237 2.19e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 44.78  E-value: 2.19e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469    2 SPGQLPSDS--IKVVPGRSKLRVESSNPVARGNPT-----PRASKVKLLSPEEAMKLTSGGNGVAVSPVKPARATSQVPK 74
Cdd:PHA03307   39 SQGQLVSDSaeLAAVTVVAGAAACDRFEPPTGPPPgpgteAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPP 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   75 RVPPSRTPE---APRSVPACPIPEIPRPVPARPTPETPRPVTARPTPEIPRPVPARPISEVQTLVPTRPTSTAPSPVSAH 151
Cdd:PHA03307  119 PTPPPASPPpspAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTP 198

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  152 PTSVVPSPVSVHPTSV--APSPVSACLTSEASKPVLANPAAGIRRELVCSLRALSMTTTPV--RQRTTPSLLKSKKVEPP 227
Cdd:PHA03307  199 PAAASPRPPRRSSPISasASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRpaPITLPTRIWEASGWNGP 278

                         250
                  ....*....|
gi 240256469  228 SPRALQIRSR 237
Cdd:PHA03307  279 SSRPGPASSS 288
PLN03209 PLN03209
translocon at the inner envelope of chloroplast subunit 62; Provisional
 8-227 2.52e-04

translocon at the inner envelope of chloroplast subunit 62; Provisional


Pssm-ID: 178748 [Multi-domain]  Cd Length: 576  Bit Score: 44.15  E-value: 2.52e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   8 SDSIKVVPGRSKLRVESSNPVARGNPTPRASKVKLLSPEeamkltsggngVAVSPVKParATSQVPkrVPPSRTPEAPRS 87
Cdd:PLN03209 336 ADGPKPVPTKPVTPEAPSPPIEEEPPQPKAVVPRPLSPY-----------TAYEDLKP--PTSPIP--TPPSSSPASSKS 400

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  88 VPACPIPEIPRPVPArPTPETPRPVTARPTPEIPRPVPARPISEVQTLVPtrPTSTAPSPVSAHPTSVVPSPVSvhpTSV 167
Cdd:PLN03209 401 VDAVAKPAEPDVVPS-PGSASNVPEVEPAQVEAKKTRPLSPYARYEDLKP--PTSPSPTAPTGVSPSVSSTSSV---PAV 474

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469 168 APSPVSACLTSEASKPvlanPAAGIRRELVCSLRALSMTTTPVRQRTTPSLLKSKKVEPP 227
Cdd:PLN03209 475 PDTAPATAATDAAAPP----PANMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVV 530
PHA03247 PHA03247
large tegument protein UL36; Provisional
 59-231 2.77e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.54  E-value: 2.77e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   59 AVSPVKPARATSQVPKRVPPS----RTPEAPRSVPACPIPeiPRPVPARPTPETPRPVTARPTP-EIPRPVP-ARPISEV 132
Cdd:PHA03247 2574 APRPSEPAVTSRARRPDAPPQsarpRAPVDDRGDPRGPAP--PSPLPPDTHAPDPPPPSPSPAAnEPDPHPPpTVPPPER 2651

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  133 QTLVPTRPTSTAPSPVSAHPTSVVPSPVSVHPTSVAPSPVSACLTSEASKPVLANPAAGIRRELVcslRALSMTTTPVRQ 212
Cdd:PHA03247 2652 PRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALV---SATPLPPGPAAA 2728

                         170
                  ....*....|....*....
gi 240256469  213 RTTPSLLKSKKVEPPSPRA 231
Cdd:PHA03247 2729 RQASPALPAAPAPPAVPAG 2747
rne PRK10811
ribonuclease E; Reviewed
 58-189 3.22e-04

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 43.87  E-value: 3.22e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   58 VAVSPVKPARATSQVPKRVPPSRTPEAPRSVPACPIPEIPRPVPARPTPETPRPVT------ARPTPEIPRPV--PARPI 129
Cdd:PRK10811  877 AAVEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAAPVTEQPQVITesdvavAQEVAEHAEPVvePQDET 956

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 240256469  130 SEVQTLVPTRPTSTAPSPVSAHPTSVVPSPVSVH-------PTSVAPSPVSACLTSE--ASKPVLANPA 189
Cdd:PRK10811  957 ADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEvetvtavEPEVAPAQVPEATVEHnhATAPMTRAPA 1025
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 65-172 3.72e-04

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 43.99  E-value: 3.72e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   65 PARATSQVPKRVPPSRTPEAPRSVPACPIP-EIP--RPVPARPTPETPRPVTARPTPEIPRPVPARPISEVQTLVPTRPT 141
Cdd:pfam03154 320 QSQQRIHTPPSQSQLQSQQPPREQPLPPAPlSMPhiKPPPTTPIPQLPNPQSHKHPPHLSGPSPFQMNSNLPPPPALKPL 399

                          90       100       110
                  ....*....|....*....|....*....|...
gi 240256469  142 STAPSpvsAHPTSVVPSPVSVHPTS--VAPSPV 172
Cdd:pfam03154 400 SSLST---HHPPSAHPPPLQLMPQSqqLPPPPA 429
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 70-178 5.28e-04

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 43.22  E-value: 5.28e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   70 SQVPKRVPPSRTPEAPRS----VPACPIPEIprPVPARPTPETPRPVTARPTPEIPR--PVPARPISEVQTL-VPTRPTS 142
Cdd:pfam03154 287 SHMQHPVPPQPFPLTPQSsqsqVPPGPSPAA--PGQSQQRIHTPPSQSQLQSQQPPReqPLPPAPLSMPHIKpPPTTPIP 364

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 240256469  143 TAPSPVS-AHPTSVV-PSPVSVhPTSVAPSPVSACLTS 178
Cdd:pfam03154 365 QLPNPQShKHPPHLSgPSPFQM-NSNLPPPPALKPLSS 401
PHA03379 PHA03379
EBNA-3A; Provisional
 61-172 5.57e-04

EBNA-3A; Provisional


Pssm-ID: 223066 [Multi-domain]  Cd Length: 935  Bit Score: 43.12  E-value: 5.57e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  61 SPVKPARATSQVPKRVPPSRTPEAPRSVPACPIPEIPRPVPARPTPETPRPVTARPTPEIPRPVPARPISEVQTLVPTRP 140
Cdd:PHA03379 473 GPLQDLEPGDQLPGVVQDGRPACAPVPAPAGPIVRPWEASLSQVPGVAFAPVMPQPMPVEPVPVPTVALERPVCPAPPLI 552

                         90       100       110
                 ....*....|....*....|....*....|..
gi 240256469 141 TSTAPspvsAHPTSVVPSPVSVHPTSVAPSPV 172
Cdd:PHA03379 553 AMQGP----GETSGIVRVRERWRPAPWTPNPP 580
PHA03247 PHA03247
large tegument protein UL36; Provisional
 78-209 5.89e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.39  E-value: 5.89e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   78 PSRTPEAPRSVPACPIPEIPRPVParPTPETPRPVTARPTPEIPRPVPARpisevqtlvptRPTSTAPSPVSAHPTSVVP 157
Cdd:PHA03247  405 TRPAAPVPASVPTPAPTPVPASAP--PPPATPLPSAEPGSDDGPAPPPER-----------QPPAPATEPAPDDPDDATR 471

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 240256469  158 SPVSVHPTSVAPSPVSACLT--------SEASKPVLANPAAGIRRELV-CSLRALSMTTTP 209
Cdd:PHA03247  472 KALDALRERRPPEPPGADLAellgrhpdTAGTVVRLAAREAAIAREVAeCSRLTINALRSP 532
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 33-228 6.77e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 42.98  E-value: 6.77e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   33 PTPRASKVKL--LSPEEAMKlTSGGNGVAVSPVkparATSQVPKRVPPSRTPEAPRSVPACPIPEIPRPVPARPTPE--- 107
Cdd:pfam05109 530 PTPNATSPTLgkTSPTSAVT-TPTPNATSPTPA----VTTPTPNATIPTLGKTSPTSAVTTPTPNATSPTVGETSPQant 604

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  108 --------TPRPVTARP---------------TPEIPRPVPARPISEVQTLVPT---RPTSTAPSPVSAHPT------SV 155
Cdd:pfam05109 605 tnhtlggtSSTPVVTSPpknatsavttgqhniTSSSTSSMSLRPSSISETLSPStsdNSTSHMPLLTSAHPTggenitQV 684

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 240256469  156 VPSPVSVHPTSVAPSPVSACLTSEASKPvlANPAAGIRRELVCSLRAlsmttTPVRQRTTPSLLKSKKVEPPS 228
Cdd:pfam05109 685 TPASTSTHHVSTSSPAPRPGTTSQASGP--GNSSTSTKPGEVNVTKG-----TPPKNATSPQAPSGQKTAVPT 750
PRK14965 PRK14965
DNA polymerase III subunits gamma and tau; Provisional
 57-256 7.70e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237871 [Multi-domain]  Cd Length: 576  Bit Score: 42.42  E-value: 7.70e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  57 GVAVSPVKPARATSQVPKRVPP-SRTPEAPRSVPACPIPEIPRPVPARPTPETPRPVTARPTPeiPRPVPARPISEVQTL 135
Cdd:PRK14965 380 GAPAPPSAAWGAPTPAAPAAPPpAAAPPVPPAAPARPAAARPAPAPAPPAAAAPPARSADPAA--AASAGDRWRAFVAFV 457

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469 136 VPTRPTsTAPSPVSAHPTSVVPSPVSVH--PTSVAPSPVSACLTSEASKPVLanpAAGIRRELVCSLRALSMTTTPVrqr 213
Cdd:PRK14965 458 KGKKPA-LGASLEQGSPLGVSAGLLEIGfpEGSFELSAMQDPDSRAELKALA---EQFFGRPTRLRITVLAAPPGAA--- 530

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 240256469 214 tTPSLLKSKKVEPPSPRAlqirsRVKQQA------ANATKIQQGAIVEV 256
Cdd:PRK14965 531 -PPSLAEKKAAEREQRQA-----RLREEArehplvQEALRVFGGEIDEV 573
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 32-181 9.13e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 42.60  E-value: 9.13e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   32 NPTPRASKVKLLSPEeamkLTSGGNGV------AVSPVkPArATSQVPKRVPPSRTPEAPRSVPACPIPEIPRPVPA--R 103
Cdd:pfam05109 491 SPSPRDNGTESKAPD----MTSPTSAVttptpnATSPT-PA-VTTPTPNATSPTLGKTSPTSAVTTPTPNATSPTPAvtT 564

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  104 PTPETPRPVTAR--PTPEIPRPVPARPISEVQTLVPTRPTS------TAPSPVSAHPTSVVPSPV----------SVHPT 165
Cdd:pfam05109 565 PTPNATIPTLGKtsPTSAVTTPTPNATSPTVGETSPQANTTnhtlggTSSTPVVTSPPKNATSAVttgqhnitssSTSSM 644

                         170
                  ....*....|....*.
gi 240256469  166 SVAPSPVSACLTSEAS 181
Cdd:pfam05109 645 SLRPSSISETLSPSTS 660
PHA03379 PHA03379
EBNA-3A; Provisional
 21-242 1.14e-03

EBNA-3A; Provisional


Pssm-ID: 223066 [Multi-domain]  Cd Length: 935  Bit Score: 42.35  E-value: 1.14e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  21 RVESSNPVARGNPTPRASKVKLLSPEEAMKLTSGGNGVAVSPVKPARATSQVPKRVPPSRTPEAPRSVPACPIPEIPRPV 100
Cdd:PHA03379 367 RIVSREGTKRKRPPIFLRRLHRLLLMRAGKLTERAREALEKASEPTYGTPRPPVEKPRPEVPQSLETATSHGSAQVPEPP 446

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469 101 P----------------------ARPTPETPR---------PVTARPTPEiPRPVPARPISEVQTLVPTRPTSTAPSPVS 149
Cdd:PHA03379 447 PvhdlepgplhdqhsmapcpvaqLPPGPLQDLepgdqlpgvVQDGRPACA-PVPAPAGPIVRPWEASLSQVPGVAFAPVM 525

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469 150 AHPTSV--VPSPVSVHPTSVAPSPVSACLTSEASkpvlanpAAGIRRELVcSLRALSMTTTPVRqrttpsllkskkvePP 227
Cdd:PHA03379 526 PQPMPVepVPVPTVALERPVCPAPPLIAMQGPGE-------TSGIVRVRE-RWRPAPWTPNPPR--------------SP 583

                        250
                 ....*....|....*.
gi 240256469 228 SPRALQIR-SRVKQQA 242
Cdd:PHA03379 584 SQMSVRDRlARLRAEA 599
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 17-209 1.19e-03

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 41.87  E-value: 1.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   17 RSKLRVESSNPVAR------GNPTPR---ASKVKLLSPEEAMKLTSGGNGVAVSPVKPAR----------------ATSQ 71
Cdd:pfam17823 151 RANASAAPRAAIAAasaphaASPAPRtaaSSTTAASSTTAASSAPTTAASSAPATLTPARgistaatatghpaagtALAA 230

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   72 VPKRVPPSRTPEAPRSVP-----------------ACPIPEIPRPVPARPTP--ETPRPVTARPTPEIPRPVPARPISEV 132
Cdd:pfam17823 231 VGNSSPAAGTVTAAVGTVtpaalatlaaaagtvasAAGTINMGDPHARRLSPakHMPSDTMARNPAAPMGAQAQGPIIQV 310

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 240256469  133 QTLVPTRPTSTAPSPVSAHPTSVVPSPVSVHPTSVAPSPVSACLTSEASkpvlANPAAGIRRELVCSLRALSMTTTP 209
Cdd:pfam17823 311 STDQPVHNTAGEPTPSPSNTTLEPNTPKSVASTNLAVVTTTKAQAKEPS----ASPVPVLHTSMIPEVEATSPTTQP 383
PRK10819 PRK10819
transport protein TonB; Provisional
 83-241 1.31e-03

transport protein TonB; Provisional


Pssm-ID: 236768 [Multi-domain]  Cd Length: 246  Bit Score: 40.82  E-value: 1.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  83 EAPRSVPACPIPEI---PRPVPArPTPETPRPVTARPTPEIPRPVPA---RPISEVQTlVPTRPtstaPSPVSAHPTSVV 156
Cdd:PRK10819  59 EPPQAVQPPPEPVVepePEPEPI-PEPPKEAPVVIPKPEPKPKPKPKpkpKPVKKVEE-QPKRE----VKPVEPRPASPF 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469 157 PSPVSVHPTSVAPSPVsacltseASKPVLANPAagirrelvcSLRALSmtttpvrqrttpsllKSKKVEPPSPRALQIRS 236
Cdd:PRK10819 133 ENTAPARPTSSTATAA-------ASKPVTSVSS---------GPRALS---------------RNQPQYPARAQALRIEG 181


                 ....*
gi 240256469 237 RVKQQ 241
Cdd:PRK10819 182 QVKVK 186
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 2-235 1.34e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 41.98  E-value: 1.34e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   2 SPGQLPSDSIKVVPGRSKLRVESSNPVARGNPT-PRASKVKLlSPEEAMKLTSggngvAVSPVKPARATS-------QVP 73
Cdd:PTZ00449 548 KPGETKEGEVGKKPGPAKEHKPSKIPTLSKKPEfPKDPKHPK-DPEEPKKPKR-----PRSAQRPTRPKSpklpellDIP 621

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  74 KRVPPSRTPEAPRSVPACPIPEIPRpvparpTPETPRPVTARPTPEIPRPvPARPiSEVQTLVPTRPTSTAPSPVSAHPT 153
Cdd:PTZ00449 622 KSPKRPESPKSPKRPPPPQRPSSPE------RPEGPKIIKSPKPPKSPKP-PFDP-KFKEKFYDDYLDAAAKSKETKTTV 693

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469 154 SVVPSPVSVHPTSVAPSPVSACLTSEASKPVLAnpaagirrelvcslRALSMTTTPVRQRTTPSLLKSKKVEPPSPRALQ 233
Cdd:PTZ00449 694 VLDESFESILKETLPETPGTPFTTPRPLPPKLP--------------RDEEFPFEPIGDPDAEQPDDIEFFTPPEEERTF 759


                 ..
gi 240256469 234 IR 235
Cdd:PTZ00449 760 FH 761
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
 35-166 1.67e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 41.59  E-value: 1.67e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  35 PRASKVKLLSPEEAMKLTSGGNGvAVSPVKPARATSQVPKRVPPSRTPEAPRSVPACPIPEIPRPVPArPTPETPRPvTA 114
Cdd:PRK14959 363 PRLMPVESLRPSGGGASAPSGSA-AEGPASGGAATIPTPGTQGPQGTAPAAGMTPSSAAPATPAPSAA-PSPRVPWD-DA 439

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 240256469 115 RPTPEI----PRPVPARPISevqTLVPTRPTSTApSPVSAHPTSVVPSPVSVHPTS 166
Cdd:PRK14959 440 PPAPPRsgipPRPAPRMPEA---SPVPGAPDSVA-SASDAPPTLGDPSDTAEHTPS 491
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
13-200 1.72e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 41.40  E-value: 1.72e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  13 VVPGRSKLRVESSNPVARGNPTPRASKVKLLSPEEAMKLTSGGNG-VAVSPVKPARATSQVPKRVPPSRTPEAPRSVPAC 91
Cdd:PRK12323 385 PAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPApEALAAARQASARGPGGAPAPAPAPAAAPAAAARP 464

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  92 PIPEIPRPVPARPTPETPRPVTARPTP---------EIPRPVPARPISEVQTLVPTRPTSTAPSPVSAHPT------SVV 156
Cdd:PRK12323 465 AAAGPRPVAAAAAAAPARAAPAAAPAPadddpppweELPPEFASPAPAQPDAAPAGWVAESIPDPATADPDdafetlAPA 544

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 240256469 157 PSPVSVHPTSVAPSPVSACLTSEASKPVLANPAAGIRRELVCSL 200
Cdd:PRK12323 545 PAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDGDWPALAARL 588
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
48-232 1.73e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 41.40  E-value: 1.73e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  48 AMKLTSGGNGVAVSPVKPARATSQVPKRVPPSRTPEAPRSVPACPIPEIPRPVPARPTPETP-------------RPVTA 114
Cdd:PRK12323 362 AFRPGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAParrspapealaaaRQASA 441

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469 115 RPTPEIPRPVPARPISEV-------QTLVPTRPTSTAPSPVSAHPTSVVPSPVSVHPTSVAPSPVSACLTSEASKPVLAN 187
Cdd:PRK12323 442 RGPGGAPAPAPAPAAAPAaaarpaaAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGW 521

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 240256469 188 PAAGIRRELVCSLRAL--SMTTTPVRQRTTPSLLKSKKVEPPSPRAL 232
Cdd:PRK12323 522 VAESIPDPATADPDDAfeTLAPAPAAAPAPRAAAATEPVVAPRPPRA 568
PHA03378 PHA03378
EBNA-3B; Provisional
 2-189 1.80e-03

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 41.59  E-value: 1.80e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   2 SPGQLPSDSIKVVPGRSKLRVESSNPVARGNPT---PRASKVKLLSPEEAMKLTSGGNGVAVSPVKPARATSQVPKRVPP 78
Cdd:PHA03378 700 APTPMRPPAAPPGRAQRPAAATGRARPPAAAPGrarPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGAPTPQPP 779

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  79 SRTPEAPRSVP-ACPIPEIPRPVPARPTPETPR--PVTARPTPEIPRPVP------ARPISEVQT-LVPTRPTSTAPSPV 148
Cdd:PHA03378 780 PQAPPAPQQRPrGAPTPQPPPQAGPTSMQLMPRaaPGQQGPTKQILRQLLtggvkrGRPSLKKPAaLERQAAAGPTPSPG 859

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 240256469 149 SAHPTSVVPSPVsVHPTSVAPSPVSACLTSeaSKPVLANPA 189
Cdd:PHA03378 860 SGTSDKIVQAPV-FYPPVLQPIQVMRQLGS--VRAAAASTV 897
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 23-247 1.97e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 41.70  E-value: 1.97e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   23 ESSNPVARGNPTPRASKVKLLSPEEAmKLTSGGNGVAVSPVKPARATSQVPKRVPPSRTPEAPRSVPA------------ 90
Cdd:PHA03307  157 ASPAAVASDAASSRQAALPLSSPEET-ARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPApgrsaaddagas 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   91 --------------CPIPEIPRPVPARPTPETPRPVTARPTPEIPRPVPARPISevqtlvPTRPTSTAPSPVSAHPTSVV 156
Cdd:PHA03307  236 ssdssssessgcgwGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSS------SPRERSPSPSPSSPGSGPAP 309

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  157 PSPVSVhpTSVAPSPVSACLTSEASKPVLANPAAGIRRELvcslralsmTTTPVRQRTTPSLlkskkvePPSPRALQIRS 236
Cdd:PHA03307  310 SSPRAS--SSSSSSRESSSSSTSSSSESSRGAAVSPGPSP---------SRSPSPSRPPPPA-------DPSSPRKRPRP 371

                         250
                  ....*....|.
gi 240256469  237 RVKQQAANATK 247
Cdd:PHA03307  372 SRAPSSPAASA 382
Cuticle_3 pfam11018
Pupal cuticle protein C1; Insect cuticles are composite structures whose mechanical properties ...
 63-192 2.01e-03

Pupal cuticle protein C1; Insect cuticles are composite structures whose mechanical properties are optimized for biological function. The major components are the chitin filament system and the cuticular proteins, and the cuticle's properties are determined largely by the interactions between these two sets of molecules. The proteins can be ordered by species.


Pssm-ID: 431611 [Multi-domain]  Cd Length: 182  Bit Score: 39.75  E-value: 2.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   63 VKPARATSQVPKRVppSRTPEAPRSVPACPIPEIPRPVPARPTPETPRPVTARPTPEIPRPVPARPISEVQT----LVPT 138
Cdd:pfam11018  28 VTPYSSVSKVDSRI--TNNVYTPKTLYSAPAPVVTKSAYAAPAPVVTTYAHAAPAPVVAKTVYAAPAVVVYAapapVVAK 105

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 240256469  139 RPTSTAPSPVSAHPTSVV-------PSPVSVHPTSVAPSPVSACLTSEASKP--VLANPAAGI 192
Cdd:pfam11018 106 TVTYAAPAVHYAAPAPVVaktvyaaPAVQHYAAPAPVEAAAHAAPVVAAAPAayVKYSPAVVV 168
Pneumo_att_G pfam05539
Pneumovirinae attachment membrane glycoprotein G;
15-154 2.17e-03

Pneumovirinae attachment membrane glycoprotein G;


Pssm-ID: 114270 [Multi-domain]  Cd Length: 408  Bit Score: 40.80  E-value: 2.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   15 PGRSKLRVESSNPV-ARGNPTPRASKVKLLSPeeamkltSGGNGVAVSPVKPARATSQVPKRVPPSRTPEAPRSVPacPI 93
Cdd:pfam05539 206 TATANQRLSSTEPVgTQGTTTSSNPEPQTEPP-------PSQRGPSGSPQHPPSTTSQDQSTTGDGQEHTQRRKTP--PA 276

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 240256469   94 PEIPRPV--PARPTPETPRPVTARPTPeiprpvpaRPISEVQtlVPTRPTSTAPSPVSAHPTS 154
Cdd:pfam05539 277 TSNRRSPhsTATPPPTTKRQETGRPTP--------RPTATTQ--SGSSPPHSSPPGVQANPTT 329
PRK12727 PRK12727
flagellar biosynthesis protein FlhF;
33-190 2.17e-03

flagellar biosynthesis protein FlhF;


Pssm-ID: 237182 [Multi-domain]  Cd Length: 559  Bit Score: 41.13  E-value: 2.17e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  33 PTPRASKVKLLSPEEAMKLTSGGNGV--AVSPVKPARATSQvPKRVPPSRTPEAPRSVPACPIPEIPRPVPARPTPETPR 110
Cdd:PRK12727  76 PTKPAAPVHAPLKLSANANMSQRQRVasAAEDMIAAMALRQ-PVSVPRQAPAAAPVRAASIPSPAAQALAHAAAVRTAPR 154

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469 111 PVTARPT-PE---------IPRPVPARPISEVQTLVPTrPTSTAPSPVSA-----HPTSVVPSPVSVH---PTSVAPSPV 172
Cdd:PRK12727 155 QEHALSAvPEqlfadflttAPVPRAPVQAPVVAAPAPV-PAIAAALAAHAayaqdDDEQLDDDGFDLDdalPQILPPAAL 233

                        170
                 ....*....|....*...
gi 240256469 173 SACLTSEASKPVLANPAA 190
Cdd:PRK12727 234 PPIVVAPAAPAALAAVAA 251
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
 62-194 2.26e-03

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 40.52  E-value: 2.26e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  62 PVKPARATSQVPKRVPPSRTPEAPRSVPACPIPEIPRPVPARPTPETPRPVT----ARPTPEIPRPVPARPISEVQTLVP 137
Cdd:NF040712 192 FGRPLRPLATVPRLAREPADARPEEVEPAPAAEGAPATDSDPAEAGTPDDLAsarrRRAGVEQPEDEPVGPGAAPAAEPD 271

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 240256469 138 TRPTSTAPSPVSAHPtsvvPSPVSVHPTSVAPSPVSACLTSEASKPVLANPAAGIRR 194
Cdd:NF040712 272 EATRDAGEPPAPGAA----ETPEAAEPPAPAPAAPAAPAAPEAEEPARPEPPPAPKP 324
PHA03132 PHA03132
thymidine kinase; Provisional
 76-182 2.41e-03

thymidine kinase; Provisional


Pssm-ID: 222997 [Multi-domain]  Cd Length: 580  Bit Score: 40.90  E-value: 2.41e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  76 VPPSRTPEAPRSVPACPIPEIPR-PVPARPTPETPRPVTARPtPEIPRPVPARPISEVQTLVP-TRPTSTAPSPVS--AH 151
Cdd:PHA03132  54 LYPPRETGSGGGVATSTIYTVPRpPRGPEQTLDKPDSLPASR-ELPPGPTPVPPGGFRGASSPrLGADSTSPRFLYqvNF 132

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 240256469 152 PTSVVPS--------PVSVHPTSVAPSPVSACLTSEASK 182
Cdd:PHA03132 133 PVILAPIgesnssseELSEEEEHSRPPPSESLKVKNGGK 171
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
27-172 2.87e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 41.01  E-value: 2.87e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  27 PVARGNPTPRASKVKLLSPEEAMKlTSGGNGVAVSPVKPARATSQVPKRVPPSRTP--EAPRSVPACPIPEIPRPVPARP 104
Cdd:PRK12323 444 PGGAPAPAPAPAAAPAAAARPAAA-GPRPVAAAAAAAPARAAPAAAPAPADDDPPPweELPPEFASPAPAQPDAAPAGWV 522

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 240256469 105 TPETPRPVTARPTPEIPRPVPARPISEVQTLVPTRPTSTAPSPVSAHPTSVVPSPVSVHPTSVAPSPV 172
Cdd:PRK12323 523 AESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDGDWPALAARLPV 590
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 59-132 3.59e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 40.56  E-value: 3.59e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  59 AVSPVKPARATSQVPKRVPPSRTPEA-PRSVPACPIPEIPRPVpARPTPETPRPV-----TARPTPEIPRPVPARPISEV 132
Cdd:PRK14950 375 APSPVRPTPAPSTRPKAAAAANIPPKePVRETATPPPVPPRPV-APPVPHTPESApkltrAAIPVDEKPKYTPPAPPKEE 453
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 2-171 3.95e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 40.54  E-value: 3.95e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469    2 SPGQLPSDSIKVVPG--RSKLRVESSNPVARGNPTPRASKVKLLSPEEAMKLTSGGNGVAVSPVKPARATSqvpkRVPPS 79
Cdd:PHA03307  261 APITLPTRIWEASGWngPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSS----SSESS 336

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   80 RTPEAPRSVPACPIPEIPRPVPARPTPETPRPVTARPTPEIPRPVPARPISE--VQTLVPTRPTSTAPSPVSAHPTSVVP 157
Cdd:PHA03307  337 RGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRraRAAVAGRARRRDATGRFPAGRPRPSP 416

                         170
                  ....*....|....
gi 240256469  158 SPVSVHPTSVAPSP 171
Cdd:PHA03307  417 LDAGAASGAFYARY 430
PLN03209 PLN03209
translocon at the inner envelope of chloroplast subunit 62; Provisional
 74-290 4.81e-03

translocon at the inner envelope of chloroplast subunit 62; Provisional


Pssm-ID: 178748 [Multi-domain]  Cd Length: 576  Bit Score: 39.91  E-value: 4.81e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  74 KRVPP--SRTPEAPRSVPACPIPEIPRPVPARPTPETPRPVTARP-TPEIP--------RPVPARPISEVQTLVPTRPTS 142
Cdd:PLN03209 326 QRVPPkeSDAADGPKPVPTKPVTPEAPSPPIEEEPPQPKAVVPRPlSPYTAyedlkpptSPIPTPPSSSPASSKSVDAVA 405

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469 143 ---TAPSPVSAHPTSVVP---------------SPVSVH-----PTSVAPSPVSACLTSEASKPVL------ANPAAGIR 193
Cdd:PLN03209 406 kpaEPDVVPSPGSASNVPevepaqveakktrplSPYARYedlkpPTSPSPTAPTGVSPSVSSTSSVpavpdtAPATAATD 485

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469 194 RELVCSLRALSMTTTPVRQRTTPsllkskkvePPSPRALQIRSRVKQQAANATKIQQGAIVEVGDKAKDHGSNEIRRSVS 273
Cdd:PLN03209 486 AAAPPPANMRPLSPYAVYDDLKP---------PTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALADEQHHAQPKPRPLS 556

                        250
                 ....*....|....*..
gi 240256469 274 EEELSELLQylPAQNPT 290
Cdd:PLN03209 557 PYTMYEDLK--PPTSPT 571
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 33-123 5.56e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 39.79  E-value: 5.56e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  33 PTPRASKVKLLSPEEAMKLTSGgngvAVSPVKPARATSQVPKRVPPSRTPEAPRSVpACPIPEIPRPVPARPTPETPRPV 112
Cdd:PRK14950 366 PQPAKPTAAAPSPVRPTPAPST----RPKAAAAANIPPKEPVRETATPPPVPPRPV-APPVPHTPESAPKLTRAAIPVDE 440

                         90
                 ....*....|.
gi 240256469 113 TARPTPEIPRP 123
Cdd:PRK14950 441 KPKYTPPAPPK 451
PHA03264 PHA03264
envelope glycoprotein D; Provisional
 22-112 5.91e-03

envelope glycoprotein D; Provisional


Pssm-ID: 223029 [Multi-domain]  Cd Length: 416  Bit Score: 39.60  E-value: 5.91e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  22 VESSNPVARGNPTPRASKVKLLSPEEAMKLTSGGNGVAVSPVKPARATSQVPKRVPPSRTPEA--PRSVPACPIPEIPRP 99
Cdd:PHA03264 270 PSGGSPAPPGDDRPEAKPEPGPVEDGAPGRETGGEGEGPEPAGRDGAAGGEPKPGPPRPAPDAdrPEGWPSLEAITFPPP 349

                         90
                 ....*....|...
gi 240256469 100 VPARPTPETPRPV 112
Cdd:PHA03264 350 TPATPAVPRARPV 362
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 64-232 6.26e-03

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 39.75  E-value: 6.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   64 KPARATSQVPKRVPPSRTPEAPRSVPACPIPEIPRPVPARPTPETPRPvtarPTPEIPRPVPARPISEVQTLVPTR---- 139
Cdd:pfam03154 170 QPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQP----PNQTQSTAAPHTLIQQTPTLHPQRlpsp 245

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  140 --PTSTAPSPVSAHPTSVVPSPVSVHPTSVAPSPVS-ACLTSEASKPVLANPAAGIRRELVCSLRALSMTTTPV----RQ 212
Cdd:pfam03154 246 hpPLQPMTQPPPPSQVSPQPLPQPSLHGQMPPMPHSlQTGPSHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAPGqsqqRI 325

                         170       180
                  ....*....|....*....|
gi 240256469  213 RTTPSLLKSKKVEPPSPRAL 232
Cdd:pfam03154 326 HTPPSQSQLQSQQPPREQPL 345
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 7-171 7.03e-03

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 39.37  E-value: 7.03e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   7 PSDSIKVVPGRSKLRV--ESSNPVARGNPTPRASKvkllsPEEAMKLTSGGNGVAVSPVKPARATSQVPKRVPPSRTPEA 84
Cdd:NF033839 328 PKPEVKPQPEKPKPEVkpQLETPKPEVKPQPEKPK-----PEVKPQPEKPKPEVKPQPETPKPEVKPQPEKPKPEVKPQP 402

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  85 PRSVPAC-PIPEIPRPvPARPTPETPRPvTARPTPEIP----RPVPARPISEVQTLVPTRPTSTAPSPVSAHPtSVVPSP 159
Cdd:NF033839 403 EKPKPEVkPQPEKPKP-EVKPQPEKPKP-EVKPQPEKPkpevKPQPEKPKPEVKPQPETPKPEVKPQPEKPKP-EVKPQP 479

                        170
                 ....*....|..
gi 240256469 160 VSVHPTSVAPSP 171
Cdd:NF033839 480 EKPKPDNSKPQA 491
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
 27-158 7.11e-03

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 38.98  E-value: 7.11e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  27 PVARGNPTPRASKVKLLSPEEAMKLTSGGNGVAVSPVKPARATSQVPKRVPPSRTPEAPRSVPACPIPEIPRPVPARPTP 106
Cdd:NF040712 201 TVPRLAREPADARPEEVEPAPAAEGAPATDSDPAEAGTPDDLASARRRRAGVEQPEDEPVGPGAAPAAEPDEATRDAGEP 280

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 240256469 107 ETPRPVTARPTPEIPRPVPARPISevqtlvPTRPTSTAPSPVSAHPTS---------VVPS 158
Cdd:NF040712 281 PAPGAAETPEAAEPPAPAPAAPAA------PAAPEAEEPARPEPPPAPkpkrrrrraSVPS 335
KAR9 pfam08580
Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal ...
 2-281 7.82e-03

Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal protein required for karyogamy, correct positioning of the mitotic spindle and for orientation of cytoplasmic microtubules. KAR9 localizes at the shmoo tip in mating cells and at the tip of the growing bud in anaphase.


Pssm-ID: 430088 [Multi-domain]  Cd Length: 684  Bit Score: 39.43  E-value: 7.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469    2 SPGQLPSDS-IKVVPGRSKLRVESSNPVARGNPTPRASKVKLLSPEEAMKLTSGGNGVAVSPVKPARATSQVP--KRVPP 78
Cdd:pfam08580 396 SKGQSLRDSlSSIFEDKNMHDTEDSPATLVANKTPGSSPPSSVIMTPVNKGSKTPSSRRGSSFDFGSSSERVInsKLRRE 475

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   79 SRTPEAPRSVPACPIP-EIPRPVPARPTPETPRPVTA---RPTPEIPRPVPARPISEVQTLVPTRPTSTAPSPVSAHPTS 154
Cdd:pfam08580 476 SKLPQIASTLKQTKRPsKIPRASPNHSGFLSTPSNTAtseTPTPALRPPSRPQPPPPGNRPRWNASTNTNDLDVGHNFKP 555

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469  155 VVPSPVSVHPTSVAPSPVSACLTSEASKPVLANPAAGIRRELVCSLRALSMTTTPV-RQRTTPSLLKSKKVEPPSPRALQ 233
Cdd:pfam08580 556 LTLTTPSPTPSRSSRSSSTLPPVSPLSRDKSRSPAPTCRSVSRASRRRASRKPTRIgSPNSRTSLLDEPPYPKLTLSKGL 635

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 240256469  234 IRSRVKQQAANATKIQQGAIVEVGDKAKDHGSNEIRRSVSEEELSELL 281
Cdd:pfam08580 636 PRTPRNRQSYAGTSPSRSVSVSSGLGPQTRPGTSLGSRFDESRLLSPL 683
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
 50-135 9.78e-03

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 39.10  E-value: 9.78e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256469   50 KLTSGGNGVAVSPVKPARATSQVPKRVPPSRTPEAPRSVPACPIPEIPRPVPARPTPETPRPVTARPTPEIPRPVPARPI 129
Cdd:PRK12270   35 DYGPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVE 114


                  ....*.
gi 240256469  130 SEVQTL 135
Cdd:PRK12270  115 DEVTPL 120
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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