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Conserved domains on  [gi|15237799|ref|NP_200710|]
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hepatocyte growth factor activator, putative (DUF3527) [Arabidopsis thaliana]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DUF3527 super family cl13476
Domain of unknown function (DUF3527); This presumed domain is functionally uncharacterized. ...
456-727 1.31e-40

Domain of unknown function (DUF3527); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is about 120 amino acids in length. This domain has a conserved CDCGGWD sequence motif.


The actual alignment was detected with superfamily member pfam12043:

Pssm-ID: 463443  Cd Length: 350  Bit Score: 152.88  E-value: 1.31e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237799   456 AVLRVTVKNNQPLFTFAVNKETDIIAATQKKMGSSEEGeCTSVYTFFSIKDHKRNSgwlnqRGSGQTHgliSNVVAQMRV 535
Cdd:pfam12043   5 GLLKCVWKNGLPHFEFSLDDPEEVYVAKTWKTDNADKA-LDYVYTFHSRKGGKKSS-----AKNGSNS---SPLVGKMKV 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237799   536 SSSLPSGS------IREFVLFSVELDRE-----STEKS------------------------------------------ 562
Cdd:pfam12043  76 SSSLCSESgesgsmETEFVLYDIPEDAQarrssSVEEKskglskkvapifrssgssisrpkskfggtssilvedpwepfs 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237799   563 -----------------DLQLKNELAAIIVKMPrlFHRRAPLN-----------TVQDHNATSGELEDHIKDKFFDQDIS 614
Cdd:pfam12043 156 gelnsddstgsypllpeDLPPNLEIAAIVVQDP--FSKRESLAvggwglkflekYGLGDATSSKEHSNLSSSESCNRNSP 233
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237799   615 A--TVILQSGVHSMP--QKGGPSSLIQRWRTGGSCDCGGWDMGCNLRILTNQHNLSYKKSATSNSPPSsnrFELFFLGEQ 690
Cdd:pfam12043 234 AsvKVVIPSGFHGGPrtRNGGPSSLLDRWRSGGGCDCGGWDMGCPLTVLNNPSINSLSDASTEEDCKS---FELFVQGSK 310
                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 15237799   691 aEEHPFLSFKPIKEGIYSVAYNSSLSQLQAFSICMAL 727
Cdd:pfam12043 311 -EKEPALRMVNVGEGLYFVDFHATLSALQSFSICVAI 346
 
Name Accession Description Interval E-value
DUF3527 pfam12043
Domain of unknown function (DUF3527); This presumed domain is functionally uncharacterized. ...
456-727 1.31e-40

Domain of unknown function (DUF3527); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is about 120 amino acids in length. This domain has a conserved CDCGGWD sequence motif.


Pssm-ID: 463443  Cd Length: 350  Bit Score: 152.88  E-value: 1.31e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237799   456 AVLRVTVKNNQPLFTFAVNKETDIIAATQKKMGSSEEGeCTSVYTFFSIKDHKRNSgwlnqRGSGQTHgliSNVVAQMRV 535
Cdd:pfam12043   5 GLLKCVWKNGLPHFEFSLDDPEEVYVAKTWKTDNADKA-LDYVYTFHSRKGGKKSS-----AKNGSNS---SPLVGKMKV 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237799   536 SSSLPSGS------IREFVLFSVELDRE-----STEKS------------------------------------------ 562
Cdd:pfam12043  76 SSSLCSESgesgsmETEFVLYDIPEDAQarrssSVEEKskglskkvapifrssgssisrpkskfggtssilvedpwepfs 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237799   563 -----------------DLQLKNELAAIIVKMPrlFHRRAPLN-----------TVQDHNATSGELEDHIKDKFFDQDIS 614
Cdd:pfam12043 156 gelnsddstgsypllpeDLPPNLEIAAIVVQDP--FSKRESLAvggwglkflekYGLGDATSSKEHSNLSSSESCNRNSP 233
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237799   615 A--TVILQSGVHSMP--QKGGPSSLIQRWRTGGSCDCGGWDMGCNLRILTNQHNLSYKKSATSNSPPSsnrFELFFLGEQ 690
Cdd:pfam12043 234 AsvKVVIPSGFHGGPrtRNGGPSSLLDRWRSGGGCDCGGWDMGCPLTVLNNPSINSLSDASTEEDCKS---FELFVQGSK 310
                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 15237799   691 aEEHPFLSFKPIKEGIYSVAYNSSLSQLQAFSICMAL 727
Cdd:pfam12043 311 -EKEPALRMVNVGEGLYFVDFHATLSALQSFSICVAI 346
 
Name Accession Description Interval E-value
DUF3527 pfam12043
Domain of unknown function (DUF3527); This presumed domain is functionally uncharacterized. ...
456-727 1.31e-40

Domain of unknown function (DUF3527); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is about 120 amino acids in length. This domain has a conserved CDCGGWD sequence motif.


Pssm-ID: 463443  Cd Length: 350  Bit Score: 152.88  E-value: 1.31e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237799   456 AVLRVTVKNNQPLFTFAVNKETDIIAATQKKMGSSEEGeCTSVYTFFSIKDHKRNSgwlnqRGSGQTHgliSNVVAQMRV 535
Cdd:pfam12043   5 GLLKCVWKNGLPHFEFSLDDPEEVYVAKTWKTDNADKA-LDYVYTFHSRKGGKKSS-----AKNGSNS---SPLVGKMKV 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237799   536 SSSLPSGS------IREFVLFSVELDRE-----STEKS------------------------------------------ 562
Cdd:pfam12043  76 SSSLCSESgesgsmETEFVLYDIPEDAQarrssSVEEKskglskkvapifrssgssisrpkskfggtssilvedpwepfs 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237799   563 -----------------DLQLKNELAAIIVKMPrlFHRRAPLN-----------TVQDHNATSGELEDHIKDKFFDQDIS 614
Cdd:pfam12043 156 gelnsddstgsypllpeDLPPNLEIAAIVVQDP--FSKRESLAvggwglkflekYGLGDATSSKEHSNLSSSESCNRNSP 233
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237799   615 A--TVILQSGVHSMP--QKGGPSSLIQRWRTGGSCDCGGWDMGCNLRILTNQHNLSYKKSATSNSPPSsnrFELFFLGEQ 690
Cdd:pfam12043 234 AsvKVVIPSGFHGGPrtRNGGPSSLLDRWRSGGGCDCGGWDMGCPLTVLNNPSINSLSDASTEEDCKS---FELFVQGSK 310
                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 15237799   691 aEEHPFLSFKPIKEGIYSVAYNSSLSQLQAFSICMAL 727
Cdd:pfam12043 311 -EKEPALRMVNVGEGLYFVDFHATLSALQSFSICVAI 346
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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