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Conserved domains on  [gi|15242954|ref|NP_200620|]
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Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

Protein Classification

disease resistance family protein( domain architecture ID 1000118)

disease resistance family protein similar to Nicotiana glutinosa TMV resistance protein N; resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via a direct or indirect interaction with this avirulence protein

Gene Ontology:  GO:0006952

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PLN03210 super family cl33662
Resistant to P. syringae 6; Provisional
 12-1040 0e+00

Resistant to P. syringae 6; Provisional


The actual alignment was detected with superfamily member PLN03210:

Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 822.20  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954    12 TWRYRVFTNFHGPDVRKTFLSHLRKQFSYNGISMFNDQSIERSQTIVPALTGAIKESRISIVVLSKNYASSRWCLDELLE 91
Cdd:PLN03210   10 NWVYDVFPSFSGEDVRITFLSHFLKELDRKLIIAFKDNEIERSQSLDPELKQAIRDSRIAVVVFSKNYASSSWCLNELLE 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954    92 ILKCREDIGQIVMTVFYGVDPSDVRKQTGEFGIAFNKTCEGKTNEETQKWSKALNDVGNIAGEHFFNWDNEAKMIEKIAR 171
Cdd:PLN03210   90 IVRCKEELGQLVIPVFYGLDPSHVRKQTGDFGEAFEKTCQNKTEDEKIQWKQALTDVANILGYHSQNWPNEAKMIEEIAN 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   172 DVSNKLNATISWDFEDMVGIEAHLQKMQSLLHLDYEDGAMiVGIYGPAGIGKTTIARALHSRLSSSFQLTCFME------ 245
Cdd:PLN03210  170 DVLGKLNLTPSNDFEDFVGIEDHIAKMSSLLHLESEEVRM-VGIWGSSGIGKTTIARALFSRLSRQFQSSVFIDrafisk 248

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   246 --NIRGSYNSglDEYGLKLRLQEQLLSKVLNHDGIRINHLGAIPERLCDQKVLIILDDVDDLQQLEALANETNWFGPGSR 323
Cdd:PLN03210  249 smEIYSSANP--DDYNMKLHLQRAFLSEILDKKDIKIYHLGAMEERLKHRKVLIFIDDLDDQDVLDALAGQTQWFGSGSR 326

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   324 IIVTTEDQELLEQHDVNKKYHVDFPTREEACKIFCTYAFRRSFAPYGFEKLAERVTWLCSNLPLGLRVMGSTLRGKKEDD 403
Cdd:PLN03210  327 IIVITKDKHFLRAHGIDHIYEVCLPSNELALEMFCRSAFKKNSPPDGFMELASEVALRAGNLPLGLNVLGSYLRGRDKED 406

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   404 WEGILRRLENSLDRKIDGVLRVGYDHLC-EDDQFLYLLIAFFFNYVDDDHVKAMLVEDNLDVKLGLKTLAYKSLIQISAE 482
Cdd:PLN03210  407 WMDMLPRLRNGLDGKIEKTLRVSYDGLNnKKDKAIFRHIACLFNGEKVNDIKLLLANSDLDVNIGLKNLVDKSLIHVRED 486

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   483 gNIVMHKLLQRVGREAIQRQ--EPTKRRILIDAREICDVLRYGKGTSNVSGISFDTSDMSEVTISDDAFKRLHDLRFLKV 560
Cdd:PLN03210  487 -IVEMHSLLQEMGKEIVRAQsnEPGEREFLVDAKDICDVLEDNTGTKKVLGITLDIDEIDELHIHENAFKGMRNLLFLKF 565

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   561 TKSRYDGK--YRMHIPAGIE-FPCLLRLLHWEAYPSKCLPPTFNPEFLVELNMQGSQLEHLWSGTQSLRNLKNMDLGWSP 637
Cdd:PLN03210  566 YTKKWDQKkeVRWHLPEGFDyLPPKLRLLRWDKYPLRCMPSNFRPENLVKLQMQGSKLEKLWDGVHSLTGLRNIDLRGSK 645

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   638 NLKELPDLTNATNLEDLNLNSCESLVEIPSSFSHLHKLKNLWMSYCINLQVIPAHMNLVSLERVTMTGCSRFRKIPVIST 717
Cdd:PLN03210  646 NLKEIPDLSMATNLETLKLSDCSSLVELPSSIQYLNKLEDLDMSRCENLEILPTGINLKSLYRLNLSGCSRLKSFPDIST 725

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   718 HINYLDIAHNTEFEVV---------------HASIALWCRL-----------HYLNMSYNENFMGLTHLPMS---LTQL- 767
Cdd:PLN03210  726 NISWLDLDETAIEEFPsnlrlenldelilceMKSEKLWERVqpltplmtmlsPSLTRLFLSDIPSLVELPSSiqnLHKLe 805

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   768 ---ILRYSDIERIPDCIKaLHQLFSLDLTGCRRLASLPELPGSLLDL--------------------------------- 811
Cdd:PLN03210  806 hleIENCINLETLPTGIN-LESLESLDLSGCSRLRTFPDISTNISDLnlsrtgieevpwwiekfsnlsfldmngcnnlqr 884

                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   812 --------------EAEDCESLETVF---SPLHTPRAL------------LNFTNCFKLGGQARRAIIRRRSEIIgkalL 862
Cdd:PLN03210  885 vslnisklkhletvDFSDCGALTEASwngSPSEVAMATdnihsklpstvcINFINCFNLDQEALLQQQSIFKQLI----L 960

                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   863 PGREVPAEFDHRAKGNSLTII-LNGYRPSYDFIQYLVCVVISPNQEITKISDSSTLLC------HTNGYIFPSYEEVYIG 935
Cdd:PLN03210  961 SGEEVPSYFTHRTTGASLTNIpLLHISPCQPFFRFRACAVVDSESFFIISVSFDIQVCcrfidrLGNHFDSPYQPHVFSV 1040

                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   936 avsKCRKEHLFIFRSGYYLNVDPSGASR------EIVFEFSSKSQDFDIIECGVkiwtaqsiergyLVFEDDN------- 1002
Cdd:PLN03210 1041 ---TKKGSHLVIFDCCFPLNEDNAPLAElnydhvDIQFRLTNKNSQLKLKGCGI------------RLSEDDSslnntlp 1105

                        1130      1140      1150
                  ....*....|....*....|....*....|....*...
gi 15242954  1003 EIKHDDHTNRVRGHYKASNVDYKSVSRKRPRKTDLKLE 1040
Cdd:PLN03210 1106 NVEEADDDNPVNGSEHWEDCEDSALERESERTKDREMR 1143
 
Name Accession Description Interval E-value
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 12-1040 0e+00

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 822.20  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954    12 TWRYRVFTNFHGPDVRKTFLSHLRKQFSYNGISMFNDQSIERSQTIVPALTGAIKESRISIVVLSKNYASSRWCLDELLE 91
Cdd:PLN03210   10 NWVYDVFPSFSGEDVRITFLSHFLKELDRKLIIAFKDNEIERSQSLDPELKQAIRDSRIAVVVFSKNYASSSWCLNELLE 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954    92 ILKCREDIGQIVMTVFYGVDPSDVRKQTGEFGIAFNKTCEGKTNEETQKWSKALNDVGNIAGEHFFNWDNEAKMIEKIAR 171
Cdd:PLN03210   90 IVRCKEELGQLVIPVFYGLDPSHVRKQTGDFGEAFEKTCQNKTEDEKIQWKQALTDVANILGYHSQNWPNEAKMIEEIAN 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   172 DVSNKLNATISWDFEDMVGIEAHLQKMQSLLHLDYEDGAMiVGIYGPAGIGKTTIARALHSRLSSSFQLTCFME------ 245
Cdd:PLN03210  170 DVLGKLNLTPSNDFEDFVGIEDHIAKMSSLLHLESEEVRM-VGIWGSSGIGKTTIARALFSRLSRQFQSSVFIDrafisk 248

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   246 --NIRGSYNSglDEYGLKLRLQEQLLSKVLNHDGIRINHLGAIPERLCDQKVLIILDDVDDLQQLEALANETNWFGPGSR 323
Cdd:PLN03210  249 smEIYSSANP--DDYNMKLHLQRAFLSEILDKKDIKIYHLGAMEERLKHRKVLIFIDDLDDQDVLDALAGQTQWFGSGSR 326

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   324 IIVTTEDQELLEQHDVNKKYHVDFPTREEACKIFCTYAFRRSFAPYGFEKLAERVTWLCSNLPLGLRVMGSTLRGKKEDD 403
Cdd:PLN03210  327 IIVITKDKHFLRAHGIDHIYEVCLPSNELALEMFCRSAFKKNSPPDGFMELASEVALRAGNLPLGLNVLGSYLRGRDKED 406

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   404 WEGILRRLENSLDRKIDGVLRVGYDHLC-EDDQFLYLLIAFFFNYVDDDHVKAMLVEDNLDVKLGLKTLAYKSLIQISAE 482
Cdd:PLN03210  407 WMDMLPRLRNGLDGKIEKTLRVSYDGLNnKKDKAIFRHIACLFNGEKVNDIKLLLANSDLDVNIGLKNLVDKSLIHVRED 486

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   483 gNIVMHKLLQRVGREAIQRQ--EPTKRRILIDAREICDVLRYGKGTSNVSGISFDTSDMSEVTISDDAFKRLHDLRFLKV 560
Cdd:PLN03210  487 -IVEMHSLLQEMGKEIVRAQsnEPGEREFLVDAKDICDVLEDNTGTKKVLGITLDIDEIDELHIHENAFKGMRNLLFLKF 565

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   561 TKSRYDGK--YRMHIPAGIE-FPCLLRLLHWEAYPSKCLPPTFNPEFLVELNMQGSQLEHLWSGTQSLRNLKNMDLGWSP 637
Cdd:PLN03210  566 YTKKWDQKkeVRWHLPEGFDyLPPKLRLLRWDKYPLRCMPSNFRPENLVKLQMQGSKLEKLWDGVHSLTGLRNIDLRGSK 645

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   638 NLKELPDLTNATNLEDLNLNSCESLVEIPSSFSHLHKLKNLWMSYCINLQVIPAHMNLVSLERVTMTGCSRFRKIPVIST 717
Cdd:PLN03210  646 NLKEIPDLSMATNLETLKLSDCSSLVELPSSIQYLNKLEDLDMSRCENLEILPTGINLKSLYRLNLSGCSRLKSFPDIST 725

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   718 HINYLDIAHNTEFEVV---------------HASIALWCRL-----------HYLNMSYNENFMGLTHLPMS---LTQL- 767
Cdd:PLN03210  726 NISWLDLDETAIEEFPsnlrlenldelilceMKSEKLWERVqpltplmtmlsPSLTRLFLSDIPSLVELPSSiqnLHKLe 805

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   768 ---ILRYSDIERIPDCIKaLHQLFSLDLTGCRRLASLPELPGSLLDL--------------------------------- 811
Cdd:PLN03210  806 hleIENCINLETLPTGIN-LESLESLDLSGCSRLRTFPDISTNISDLnlsrtgieevpwwiekfsnlsfldmngcnnlqr 884

                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   812 --------------EAEDCESLETVF---SPLHTPRAL------------LNFTNCFKLGGQARRAIIRRRSEIIgkalL 862
Cdd:PLN03210  885 vslnisklkhletvDFSDCGALTEASwngSPSEVAMATdnihsklpstvcINFINCFNLDQEALLQQQSIFKQLI----L 960

                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   863 PGREVPAEFDHRAKGNSLTII-LNGYRPSYDFIQYLVCVVISPNQEITKISDSSTLLC------HTNGYIFPSYEEVYIG 935
Cdd:PLN03210  961 SGEEVPSYFTHRTTGASLTNIpLLHISPCQPFFRFRACAVVDSESFFIISVSFDIQVCcrfidrLGNHFDSPYQPHVFSV 1040

                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   936 avsKCRKEHLFIFRSGYYLNVDPSGASR------EIVFEFSSKSQDFDIIECGVkiwtaqsiergyLVFEDDN------- 1002
Cdd:PLN03210 1041 ---TKKGSHLVIFDCCFPLNEDNAPLAElnydhvDIQFRLTNKNSQLKLKGCGI------------RLSEDDSslnntlp 1105

                        1130      1140      1150
                  ....*....|....*....|....*....|....*...
gi 15242954  1003 EIKHDDHTNRVRGHYKASNVDYKSVSRKRPRKTDLKLE 1040
Cdd:PLN03210 1106 NVEEADDDNPVNGSEHWEDCEDSALERESERTKDREMR 1143
TIR pfam01582
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ...
 15-180 1.00e-67

TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.


Pssm-ID: 396246 [Multi-domain]  Cd Length: 165  Bit Score: 224.17  E-value: 1.00e-67
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954     15 YRVFTNFHGPDVRKTFLSHLRKQFSYNGISMF-NDQSIERSQTIVPALTGAIKESRISIVVLSKNYASSRWCLDELLEIL 93
Cdd:pfam01582    1 YDVFLSFRGSDTREWFVSHLLKELKQKGIKLFiDDRDLEPGEAIAPELLSAIEKSRRSVVVLSPNYASSGWCLDELVKIL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954     94 KCREDIGQIVMTVFYGVDPSDVRKQTGEFGIAFNKTCEGKTNEETQKWSKALNDVGNIagEHFFNWDNEAKMIEKIARDV 173
Cdd:pfam01582   81 ECALDLGQKVIPIFYEVDPSDVRKQTGSFGKAFKKHKKVLTEEKVLKWRGALNEVANI--WHSKSVSDESKFWKKIAYDI 158


                   ....*..
gi 15242954    174 SNKLNAT 180
Cdd:pfam01582  159 SNKLNGT 165
TIR smart00255
Toll - interleukin 1 - resistance;
14-151 6.96e-38

Toll - interleukin 1 - resistance;


Pssm-ID: 214587 [Multi-domain]  Cd Length: 140  Bit Score: 138.61  E-value: 6.96e-38
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954      14 RYRVFTNFHG-PDVRKTFLSHLRKQFSYNGISMFNDQSIERSQtIVPALTGAIKESRISIVVLSKNYASSRWCLDELLEI 92
Cdd:smart00255    1 EYDVFISYSGkEDVRNEFLSHLLEKLRGYGLCVFIDDFEPGGG-DLEEIDEAIEKSRIAIVVLSPNYAESEWCLDELVAA 79

                            90       100       110       120       130       140
                    ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15242954      93 LKCR-EDIGQIVMTVFYGVDPSDVRKQTGEFGIAFNKTCEGKTNEET-QKWSKALNDVGNI 151
Cdd:smart00255   80 LENAlEEGGLRVIPIFYEVIPSDVRKQPGKFRKVFKKNYLKWPEDEKeQFWKKALYAVPSK 140
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
615-812 5.07e-13

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 72.27  E-value: 5.07e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954  615 LEHLWSGTQSLRNLKNMDLGWSPNLKEL-----PDLTNATNLEDLNLNSCEsLVEIPSSFSHLHKLKNLWMSYCiNLQVI 689
Cdd:COG4886   74 LLLLSLLLLSLLLLGLTDLGDLTNLTELdlsgnEELSNLTNLESLDLSGNQ-LTDLPEELANLTNLKELDLSNN-QLTDL 151

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954  690 PAhmNLVSLervtmtgcsrfrkipvisTHINYLDIAHNtEFEVVHASIALWCRLHYLNMSYNEnfmgLTHLPMS------ 763
Cdd:COG4886  152 PE--PLGNL------------------TNLKSLDLSNN-QLTDLPEELGNLTNLKELDLSNNQ----ITDLPEPlgnltn 206

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 15242954  764 LTQLILRYSDIERIPDCIKALHQLFSLDLTGCrRLASLPELpGSLLDLE 812
Cdd:COG4886  207 LEELDLSGNQLTDLPEPLANLTNLETLDLSNN-QLTDLPEL-GNLTNLE 253
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 215-335 1.36e-04

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 43.29  E-value: 1.36e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954  215 IYGPAGIGKTTIARALHSRLSSS----FQLTCfMENIRGSYNSGLDEYGLKLRLQEQLLSKvlnhdgirinhlgaiperl 290
Cdd:cd00009   24 LYGPPGTGKTTLARAIANELFRPgapfLYLNA-SDLLEGLVVAELFGHFLVRLLFELAEKA------------------- 83

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 15242954  291 cdQKVLIILDDVDD---------LQQLEALANETNWFGPGSRIIVTTEDQELLE 335
Cdd:cd00009   84 --KPGVLFIDEIDSlsrgaqnalLRVLETLNDLRIDRENVRVIGATNRPLLGDL 135
 
Name Accession Description Interval E-value
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 12-1040 0e+00

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 822.20  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954    12 TWRYRVFTNFHGPDVRKTFLSHLRKQFSYNGISMFNDQSIERSQTIVPALTGAIKESRISIVVLSKNYASSRWCLDELLE 91
Cdd:PLN03210   10 NWVYDVFPSFSGEDVRITFLSHFLKELDRKLIIAFKDNEIERSQSLDPELKQAIRDSRIAVVVFSKNYASSSWCLNELLE 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954    92 ILKCREDIGQIVMTVFYGVDPSDVRKQTGEFGIAFNKTCEGKTNEETQKWSKALNDVGNIAGEHFFNWDNEAKMIEKIAR 171
Cdd:PLN03210   90 IVRCKEELGQLVIPVFYGLDPSHVRKQTGDFGEAFEKTCQNKTEDEKIQWKQALTDVANILGYHSQNWPNEAKMIEEIAN 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   172 DVSNKLNATISWDFEDMVGIEAHLQKMQSLLHLDYEDGAMiVGIYGPAGIGKTTIARALHSRLSSSFQLTCFME------ 245
Cdd:PLN03210  170 DVLGKLNLTPSNDFEDFVGIEDHIAKMSSLLHLESEEVRM-VGIWGSSGIGKTTIARALFSRLSRQFQSSVFIDrafisk 248

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   246 --NIRGSYNSglDEYGLKLRLQEQLLSKVLNHDGIRINHLGAIPERLCDQKVLIILDDVDDLQQLEALANETNWFGPGSR 323
Cdd:PLN03210  249 smEIYSSANP--DDYNMKLHLQRAFLSEILDKKDIKIYHLGAMEERLKHRKVLIFIDDLDDQDVLDALAGQTQWFGSGSR 326

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   324 IIVTTEDQELLEQHDVNKKYHVDFPTREEACKIFCTYAFRRSFAPYGFEKLAERVTWLCSNLPLGLRVMGSTLRGKKEDD 403
Cdd:PLN03210  327 IIVITKDKHFLRAHGIDHIYEVCLPSNELALEMFCRSAFKKNSPPDGFMELASEVALRAGNLPLGLNVLGSYLRGRDKED 406

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   404 WEGILRRLENSLDRKIDGVLRVGYDHLC-EDDQFLYLLIAFFFNYVDDDHVKAMLVEDNLDVKLGLKTLAYKSLIQISAE 482
Cdd:PLN03210  407 WMDMLPRLRNGLDGKIEKTLRVSYDGLNnKKDKAIFRHIACLFNGEKVNDIKLLLANSDLDVNIGLKNLVDKSLIHVRED 486

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   483 gNIVMHKLLQRVGREAIQRQ--EPTKRRILIDAREICDVLRYGKGTSNVSGISFDTSDMSEVTISDDAFKRLHDLRFLKV 560
Cdd:PLN03210  487 -IVEMHSLLQEMGKEIVRAQsnEPGEREFLVDAKDICDVLEDNTGTKKVLGITLDIDEIDELHIHENAFKGMRNLLFLKF 565

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   561 TKSRYDGK--YRMHIPAGIE-FPCLLRLLHWEAYPSKCLPPTFNPEFLVELNMQGSQLEHLWSGTQSLRNLKNMDLGWSP 637
Cdd:PLN03210  566 YTKKWDQKkeVRWHLPEGFDyLPPKLRLLRWDKYPLRCMPSNFRPENLVKLQMQGSKLEKLWDGVHSLTGLRNIDLRGSK 645

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   638 NLKELPDLTNATNLEDLNLNSCESLVEIPSSFSHLHKLKNLWMSYCINLQVIPAHMNLVSLERVTMTGCSRFRKIPVIST 717
Cdd:PLN03210  646 NLKEIPDLSMATNLETLKLSDCSSLVELPSSIQYLNKLEDLDMSRCENLEILPTGINLKSLYRLNLSGCSRLKSFPDIST 725

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   718 HINYLDIAHNTEFEVV---------------HASIALWCRL-----------HYLNMSYNENFMGLTHLPMS---LTQL- 767
Cdd:PLN03210  726 NISWLDLDETAIEEFPsnlrlenldelilceMKSEKLWERVqpltplmtmlsPSLTRLFLSDIPSLVELPSSiqnLHKLe 805

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   768 ---ILRYSDIERIPDCIKaLHQLFSLDLTGCRRLASLPELPGSLLDL--------------------------------- 811
Cdd:PLN03210  806 hleIENCINLETLPTGIN-LESLESLDLSGCSRLRTFPDISTNISDLnlsrtgieevpwwiekfsnlsfldmngcnnlqr 884

                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   812 --------------EAEDCESLETVF---SPLHTPRAL------------LNFTNCFKLGGQARRAIIRRRSEIIgkalL 862
Cdd:PLN03210  885 vslnisklkhletvDFSDCGALTEASwngSPSEVAMATdnihsklpstvcINFINCFNLDQEALLQQQSIFKQLI----L 960

                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   863 PGREVPAEFDHRAKGNSLTII-LNGYRPSYDFIQYLVCVVISPNQEITKISDSSTLLC------HTNGYIFPSYEEVYIG 935
Cdd:PLN03210  961 SGEEVPSYFTHRTTGASLTNIpLLHISPCQPFFRFRACAVVDSESFFIISVSFDIQVCcrfidrLGNHFDSPYQPHVFSV 1040

                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   936 avsKCRKEHLFIFRSGYYLNVDPSGASR------EIVFEFSSKSQDFDIIECGVkiwtaqsiergyLVFEDDN------- 1002
Cdd:PLN03210 1041 ---TKKGSHLVIFDCCFPLNEDNAPLAElnydhvDIQFRLTNKNSQLKLKGCGI------------RLSEDDSslnntlp 1105

                        1130      1140      1150
                  ....*....|....*....|....*....|....*...
gi 15242954  1003 EIKHDDHTNRVRGHYKASNVDYKSVSRKRPRKTDLKLE 1040
Cdd:PLN03210 1106 NVEEADDDNPVNGSEHWEDCEDSALERESERTKDREMR 1143
TIR pfam01582
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ...
 15-180 1.00e-67

TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.


Pssm-ID: 396246 [Multi-domain]  Cd Length: 165  Bit Score: 224.17  E-value: 1.00e-67
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954     15 YRVFTNFHGPDVRKTFLSHLRKQFSYNGISMF-NDQSIERSQTIVPALTGAIKESRISIVVLSKNYASSRWCLDELLEIL 93
Cdd:pfam01582    1 YDVFLSFRGSDTREWFVSHLLKELKQKGIKLFiDDRDLEPGEAIAPELLSAIEKSRRSVVVLSPNYASSGWCLDELVKIL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954     94 KCREDIGQIVMTVFYGVDPSDVRKQTGEFGIAFNKTCEGKTNEETQKWSKALNDVGNIagEHFFNWDNEAKMIEKIARDV 173
Cdd:pfam01582   81 ECALDLGQKVIPIFYEVDPSDVRKQTGSFGKAFKKHKKVLTEEKVLKWRGALNEVANI--WHSKSVSDESKFWKKIAYDI 158


                   ....*..
gi 15242954    174 SNKLNAT 180
Cdd:pfam01582  159 SNKLNGT 165
TIR smart00255
Toll - interleukin 1 - resistance;
14-151 6.96e-38

Toll - interleukin 1 - resistance;


Pssm-ID: 214587 [Multi-domain]  Cd Length: 140  Bit Score: 138.61  E-value: 6.96e-38
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954      14 RYRVFTNFHG-PDVRKTFLSHLRKQFSYNGISMFNDQSIERSQtIVPALTGAIKESRISIVVLSKNYASSRWCLDELLEI 92
Cdd:smart00255    1 EYDVFISYSGkEDVRNEFLSHLLEKLRGYGLCVFIDDFEPGGG-DLEEIDEAIEKSRIAIVVLSPNYAESEWCLDELVAA 79

                            90       100       110       120       130       140
                    ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15242954      93 LKCR-EDIGQIVMTVFYGVDPSDVRKQTGEFGIAFNKTCEGKTNEET-QKWSKALNDVGNI 151
Cdd:smart00255   80 LENAlEEGGLRVIPIFYEVIPSDVRKQPGKFRKVFKKNYLKWPEDEKeQFWKKALYAVPSK 140
NB-ARC pfam00931
NB-ARC domain;
191-415 1.55e-20

NB-ARC domain;


Pssm-ID: 395745 [Multi-domain]  Cd Length: 245  Bit Score: 92.06  E-value: 1.55e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954    191 IEAHLQKMQSllHLDYEDGAMIVGIYGPAGIGKTTIARALHSRLSSsfqltcfmenIRGSYN-------SGLDEYGLKLR 263
Cdd:pfam00931    1 REDMVEKVIG--KLSEKDEPGIVGIHGMGGVGKTTLAAQIFNDFDE----------VEGHFDsvawvvvSKTFTISTLQQ 68

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954    264 --LQEQLLSKVLNHDGIRINHLGAIPERLCDQKVLIILDDVDDLQQLEALANETNWFGPGSRIIVTTEDQELLEQH-DVN 340
Cdd:pfam00931   69 tiLQNLGLSEDDWDNKEEGELARKIRRALLTKRFLLVLDDVWDEEDWDKIGIPLPDRENGCRVLLTTRSEEVAGRVgGPS 148

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15242954    341 KKYHVDFPTREEACKIFCTYAFRRSF-APYGFEKLAERVTWLCSNLPLGLRVMGSTLRGKK-EDDWEGILRRLENSL 415
Cdd:pfam00931  149 DPHEVELLEPDEAWELFENKVFPKTLgECELLEDVAKEIVEKCRGLPLALKVLGGLLSCKKtVEEWKHVYDVLQSEL 225
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
615-812 5.07e-13

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 72.27  E-value: 5.07e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954  615 LEHLWSGTQSLRNLKNMDLGWSPNLKEL-----PDLTNATNLEDLNLNSCEsLVEIPSSFSHLHKLKNLWMSYCiNLQVI 689
Cdd:COG4886   74 LLLLSLLLLSLLLLGLTDLGDLTNLTELdlsgnEELSNLTNLESLDLSGNQ-LTDLPEELANLTNLKELDLSNN-QLTDL 151

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954  690 PAhmNLVSLervtmtgcsrfrkipvisTHINYLDIAHNtEFEVVHASIALWCRLHYLNMSYNEnfmgLTHLPMS------ 763
Cdd:COG4886  152 PE--PLGNL------------------TNLKSLDLSNN-QLTDLPEELGNLTNLKELDLSNNQ----ITDLPEPlgnltn 206

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 15242954  764 LTQLILRYSDIERIPDCIKALHQLFSLDLTGCrRLASLPELpGSLLDLE 812
Cdd:COG4886  207 LEELDLSGNQLTDLPEPLANLTNLETLDLSNN-QLTDLPEL-GNLTNLE 253
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
592-803 1.22e-10

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 64.95  E-value: 1.22e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954  592 PSKCLPPTFNPEFLVELNMQGSQLEHLWSGTQSLRNLKNMDLGWSPNLKELPDLTNATNLEDLNLNSCESLVEIPSSFSH 671
Cdd:COG4886   15 LLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGD 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954  672 LHKLKNLWMSYCINLQvipahmNLVSLERVTMTGCsRFRKIPV-IS--THINYLDIAHNtEFEVVHASIALWCRLHYLNM 748
Cdd:COG4886   95 LTNLTELDLSGNEELS------NLTNLESLDLSGN-QLTDLPEeLAnlTNLKELDLSNN-QLTDLPEPLGNLTNLKSLDL 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15242954  749 SYNEnfmgLTHLPMS------LTQLILRYSDIERIPDCIKALHQLFSLDLTGCrRLASLPE 803
Cdd:COG4886  167 SNNQ----LTDLPEElgnltnLKELDLSNNQITDLPEPLGNLTNLEELDLSGN-QLTDLPE 222
TIR_2 pfam13676
TIR domain; This is a family of Toll-like receptors.
 17-103 1.83e-06

TIR domain; This is a family of Toll-like receptors.


Pssm-ID: 463954 [Multi-domain]  Cd Length: 118  Bit Score: 47.70  E-value: 1.83e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954     17 VFTNFHGPDvrKTFLSHLRKQFSYNGISMFNDQ-SIERSQTIVPALTGAIKESRISIVVLSKNYASSRWCLDELLEILKC 95
Cdd:pfam13676    1 VFISYAGED--RAWAEWLADALEAAGYRVWLDRwDIRPGDDWVEEIEEAIENSDRVLVVLSPNYLESPWCRAEWEAALAD 78


                   ....*...
gi 15242954     96 REDIGQIV 103
Cdd:pfam13676   79 PEGRKRLI 86
PLN03194 PLN03194
putative disease resistance protein; Provisional
 17-156 3.31e-06

putative disease resistance protein; Provisional


Pssm-ID: 215626 [Multi-domain]  Cd Length: 187  Bit Score: 48.66  E-value: 3.31e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954    17 VFTNFHGPDVRKTFLSHLRKQFSYNGISMFND-QSIERSQTIVPALTGAIKESRISIVVLSKNYASSRWCLDELLEILKC 95
Cdd:PLN03194   29 VFINHRGIDTKRTIATLLYDHLSRLNLRPFLDnKNMKPGDKLFDKINSAIRNCKVGVAVFSPRYCESYFCLHELALIMES 108

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15242954    96 REDigqiVMTVFYGVDPSDVRkqtgefgIAFNKTCEGktnEETQKWSKALNDVGNIAGEHF 156
Cdd:PLN03194  109 KKR----VIPIFCDVKPSQLR-------VVDNGTCPD---EEIRRFNWALEEAKYTVGLTF 155
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
605-700 2.64e-05

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 48.01  E-value: 2.64e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954  605 LVELNMQGSQLEHLWSGTQSLRNLKNMDLGWSpNLKELPDLTNATNLEDLNLNSCEsLVEIPSSfSHLHKLKNLWMSYC- 683
Cdd:COG4886  207 LEELDLSGNQLTDLPEPLANLTNLETLDLSNN-QLTDLPELGNLTNLEELDLSNNQ-LTDLPPL-ANLTNLKTLDLSNNq 283

                         90       100
                 ....*....|....*....|
gi 15242954  684 ---INLQVIPAHMNLVSLER 700
Cdd:COG4886  284 ltdLKLKELELLLGLNSLLL 303
AAA_16 pfam13191
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ...
 189-316 3.58e-05

AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.


Pssm-ID: 433025 [Multi-domain]  Cd Length: 167  Bit Score: 45.19  E-value: 3.58e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954    189 VGIEAHLQKMQSLLHLDYEDGAMIVGIYGPAGIGKTTIARALHSRLSSS---FQLTCFMENI-RGSYNSGLDEYGLKLRL 264
Cdd:pfam13191    3 VGREEELEQLLDALDRVRSGRPPSVLLTGEAGTGKTTLLRELLRALERDggyFLRGKCDENLpYSPLLEALTREGLLRQL 82

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15242954    265 QEQLLSKVLNHDGIRI--------NHLGAIPERLCD-------------QKVLIILDDVD-----DLQQLEALANETN 316
Cdd:pfam13191   83 LDELESSLLEAWRAALlealapvpELPGDLAERLLDlllrlldllargeRPLVLVLDDLQwadeaSLQLLAALLRLLE 160
LRR_3 pfam07725
Leucine Rich Repeat; This Pfam entry includes some LRRs that fail to be detected by the ...
 604-623 6.00e-05

Leucine Rich Repeat; This Pfam entry includes some LRRs that fail to be detected by the pfam00560 model.


Pssm-ID: 429621 [Multi-domain]  Cd Length: 20  Bit Score: 40.78  E-value: 6.00e-05
                           10        20
                   ....*....|....*....|
gi 15242954    604 FLVELNMQGSQLEHLWSGTQ 623
Cdd:pfam07725    1 NLVELNMPYSKLEKLWEGVK 20
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 215-335 1.36e-04

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 43.29  E-value: 1.36e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954  215 IYGPAGIGKTTIARALHSRLSSS----FQLTCfMENIRGSYNSGLDEYGLKLRLQEQLLSKvlnhdgirinhlgaiperl 290
Cdd:cd00009   24 LYGPPGTGKTTLARAIANELFRPgapfLYLNA-SDLLEGLVVAELFGHFLVRLLFELAEKA------------------- 83

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 15242954  291 cdQKVLIILDDVDD---------LQQLEALANETNWFGPGSRIIVTTEDQELLE 335
Cdd:cd00009   84 --KPGVLFIDEIDSlsrgaqnalLRVLETLNDLRIDRENVRVIGATNRPLLGDL 135
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 212-314 1.28e-03

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 40.43  E-value: 1.28e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954     212 IVGIYGPAGIGKTTIARALHSRLSSSfqltcfmeNIRGSYNSGLDEYGLKLRLQEQLLSKVLNHDGIRINHLGAIPERLC 291
Cdd:smart00382    4 VILIVGPPGSGKTTLARALARELGPP--------GGGVIYIDGEDILEEVLDQLLLIIVGGKKASGSGELRLRLALALAR 75

                            90       100
                    ....*....|....*....|....
gi 15242954     292 DQKV-LIILDDVDDLQQLEALANE 314
Cdd:smart00382   76 KLKPdVLILDEITSLLDAEQEALL 99
AAA_18 pfam13238
AAA domain;
213-335 1.66e-03

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 39.72  E-value: 1.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954    213 VGIYGPAGIGKTTIARALHSRLSSSFQLTCFMENiRGSYNSGLDEYGLKLRLQEQLLSKVLNhdgiriNHLGAIPERLCD 292
Cdd:pfam13238    1 ILITGTPGVGKTTLAKELSKRLGFGDNVRDLALE-NGLVLGDDPETRESKRLDEDKLDRLLD------LLEENAALEEGG 73

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 15242954    293 qkvLIILDDVDDLQQLEalanetnWFGPGSRIIVTTEDQELLE 335
Cdd:pfam13238   74 ---NLIIDGHLAELEPE-------RAKDLVGIVLRASPEELLE 106
ExeA COG3267
Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, ...
 201-316 1.68e-03

Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 442498 [Multi-domain]  Cd Length: 261  Bit Score: 41.31  E-value: 1.68e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954  201 LLHLDY--EDGAMIVGIYGPAGIGKTTIARALHSRLSSSFQLTCFmenirgsYNSGLDEyglklrlqEQLLSKVLNHDGI 278
Cdd:COG3267   32 LARLEYalAQGGGFVVLTGEVGTGKTTLLRRLLERLPDDVKVAYI-------PNPQLSP--------AELLRAIADELGL 96

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 15242954  279 RINH------LGAIPERLCDQ-----KVLIILDD-----VDDLQQLEALAN-ETN 316
Cdd:COG3267   97 EPKGaskadlLRQLQEFLLELaaagrRVVLIIDEaqnlpPETLEELRLLSNlETD 151
ATPase_2 pfam01637
ATPase domain predominantly from Archaea; This family contain a conserved P-loop motif that is ...
 199-308 1.72e-03

ATPase domain predominantly from Archaea; This family contain a conserved P-loop motif that is involved in binding ATP. There are eukaryote members as well as archaeal members in this family.


Pssm-ID: 376582 [Multi-domain]  Cd Length: 222  Bit Score: 41.15  E-value: 1.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954    199 QSLLHLDYEDGAMIVGIYGPAGIGKTTIARALHSRLSSSFQLTCFMENIRGSYNSGLDEYGLKLRLQEQLLSKVLNHDGI 278
Cdd:pfam01637    9 KELEEWAERGPNLIYVIYGPEGCGKTALLRESIENLLDLGYYVIYYDPLRRYFISKLDRFEEVRRLAEALGIAVPKAELE 88

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 15242954    279 RINH--------LGAIPERLcdQKVLIIlddVDDLQQL 308
Cdd:pfam01637   89 ESKLaflaiellLEALKRRG--KKIAII---IDEVQQA 121
NACHT pfam05729
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in ...
 215-336 2.08e-03

NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.


Pssm-ID: 428606 [Multi-domain]  Cd Length: 166  Bit Score: 39.98  E-value: 2.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954    215 IYGPAGIGKTTIARALHS-----RLSSSFQLTCFMEnirgsyNSGLDEYGLKLRLQEQLLSKVLNHDG-IR--INHLGAI 286
Cdd:pfam05729    5 LQGEAGSGKTTLLQKLALlwaqgKLPQGFDFVFFLP------CRELSRSGNARSLADLLFSQWPEPAApVSevWAVILEL 78

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15242954    287 PERlcdqkVLIILDDVD----DLQQLEALANETNWFG--------PGSRIIVTT------EDQELLEQ 336
Cdd:pfam05729   79 PER-----LLLILDGLDelvsDLGQLDGPCPVLTLLSsllrkkllPGASLLLTVrpdalrDLRRGLEE 141
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 624-804 2.66e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 41.76  E-value: 2.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   624 SLRNLKNMDLGWSPNLKELP-DLTNATNLEDLNLNSCESLVEIPSSFSHLHKLKNLWMSYCiNLQ-VIPAHM-NLVSLer 700
Cdd:PLN00113  162 SFSSLKVLDLGGNVLVGKIPnSLTNLTSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGYN-NLSgEIPYEIgGLTSL-- 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954   701 vtmtgcsrfrkipvisthiNYLDIAHNTEFEVVHASIALWCRLHYLNMsYNENFMGltHLPMS---LTQLI-LRYSDIE- 775
Cdd:PLN00113  239 -------------------NHLDLVYNNLTGPIPSSLGNLKNLQYLFL-YQNKLSG--PIPPSifsLQKLIsLDLSDNSl 296

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 15242954   776 --RIPDCIKALH-----QLFSLDLTGC--RRLASLPEL 804
Cdd:PLN00113  297 sgEIPELVIQLQnleilHLFSNNFTGKipVALTSLPRL 334
C-JID pfam20160
C-JID domain; C-terminal jelly roll/Ig-like domain (C-JID) was defined in cryogenic electron ...
 862-992 5.04e-03

C-JID domain; C-terminal jelly roll/Ig-like domain (C-JID) was defined in cryogenic electron microscopy (cryoEM) structures of plant intracellular immune receptors containing Toll/interleukin-1 receptor (TIR, PF01582), nucleotide-binding (NB-ARC, PF00931) and leucine-rich repeat (LRR) domains (TIR-NLRs). Structurally, the C-JID core is represented by a beta-sandwich made up of 8 to 9 beta-strands. C-JID matches the so-called post LRR domain originally detected via a set of MEME motifs. The domain showed a strong distribution bias towards TIR-NLRs of dicotyledonous plant species despite broader taxonomic distribution of TIR-NLR in plant groups. Structure-function analyses of cryoEM structures suggest that C-JID domains play a role in substrate-recognition, such as binding to effector proteins from pathogens, and thus are involved in the initiation of signaling by TIR-NLR receptors. Presence of C-JID (or post-LRR) and its importance for the function of Arabidopsis TIR-NLR RPS4 that partners with RRS1 for effector recognition suggest that C-JID has additional functions.


Pssm-ID: 466313  Cd Length: 108  Bit Score: 37.81  E-value: 5.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954    862 LPGREVPAEFDHRAKGNSLTIIL--NGYRPsyDFIQYLVCVVISPNqeitkisdsSTLLCHTnGYIFPSyeevYIGAVSK 939
Cdd:pfam20160    1 LPGSQIPEWFNHQSTGSSISIKLpeNWYND--NFLGFAVCAVGSLI---------PSLHNFL-GYIHFF----LIPLVSL 64

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 15242954    940 CRKEHLFIFRSGYYlnvdpsgasREIVFEFSSKSQDFDIIECGVKIWTAQSIE 992
Cdd:pfam20160   65 WDTSKANGKTPNDY---------GRIEASFEFPSDLHEIKQCGVRLIYKDEVE 108
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 638-795 8.10e-03

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 39.00  E-value: 8.10e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954  638 NLKELPDLTNATNLEDLNL--NSCESLveipSSFSHLHKLKNLWMSY-CI----NLQvipahmNLVSLERVtmtgcsrfr 710
Cdd:cd21340   35 KITKIENLEFLTNLTHLYLqnNQIEKI----ENLENLVNLKKLYLGGnRIsvveGLE------NLTNLEEL--------- 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954  711 kipvistHINYLDIAHNTEFEVVHASI-ALWCRLHYLNMSYN--ENFMGLTHLPmSLTQLILRY---SDIERIPDCIKAL 784
Cdd:cd21340   96 -------HIENQRLPPGEKLTFDPRSLaALSNSLRVLNISGNniDSLEPLAPLR-NLEQLDASNnqiSDLEELLDLLSSW 167

                        170
                 ....*....|.
gi 15242954  785 HQLFSLDLTGC 795
Cdd:cd21340  168 PSLRELDLTGN 178
NACHT COG5635
Predicted NTPase, NACHT family domain [Signal transduction mechanisms];
215-328 8.41e-03

Predicted NTPase, NACHT family domain [Signal transduction mechanisms];


Pssm-ID: 444362 [Multi-domain]  Cd Length: 935  Bit Score: 40.17  E-value: 8.41e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242954  215 IYGPAGIGKTT----IARALHSRLSSSFQLTCFMenIRgsynsgLDEYGLKLRLQEQLLSKVLNHDGIRINHLGAIperL 290
Cdd:COG5635  185 ILGEPGSGKTTllryLALELAERYLDAEDPIPIL--IE------LRDLAEEASLEDLLAEALEKRGGEPEDALERL---L 253

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 15242954  291 CDQKVLIILDDVDDLQQLEALANETNWFG------PGSRIIVTT 328
Cdd:COG5635  254 RNGRLLLLLDGLDEVPDEADRDEVLNQLRrfleryPKARVIITS 297
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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