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Conserved domains on  [gi|15237975|ref|NP_199501|]
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Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein [Arabidopsis thaliana]

Protein Classification

HPS-like domain-containing protein( domain architecture ID 10112930)

HPS (Hydrophobic Protein from Soybean) is a small hydrophobic protein with unknown function related to cereal-type alpha-amylase inhibitors and lipid transfer proteins

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HPS_like cd01958
HPS_like: Hydrophobic Protein from Soybean (HPS)-like subfamily; composed of proteins with ...
 46-126 2.50e-25

HPS_like: Hydrophobic Protein from Soybean (HPS)-like subfamily; composed of proteins with similarity to HPS, a small hydrophobic protein with unknown function related to cereal-type alpha-amylase inhibitors and lipid transfer proteins. In addition to HPS, members of this subfamily include a hybrid proline-rich protein (HyPRP) from maize, a dark-inducible protein (LeDI-2) from Lithospermum erythrorhizon, maize ZRP3 protein, and rice RcC3 protein. HyPRP is an embryo-specific protein that contains an N-terminal proline-rich domain and a C-terminal HPS-like cysteine-rich domain. It has been suggested that HyPRP may be involved in the stability and defense of the developing embryo. LeDI-2 is a root-specific protein that may be involved in regulating the biosynthesis of shikonin derivatives in L. erythrorhizon. Maize ZRP3 and rice RcC3 are root-specific proteins whose functions are yet to be determined. It has been reported that ZRP3 largely accumulates in a distinct subset of cortical cells.


:

Pssm-ID: 238924  Cd Length: 85  Bit Score: 91.24  E-value: 2.50e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237975  46 PTC-KDALKLKVCANVLDLVKVSL--PPTSNCCALIKGLVDLEAAVCLCTALKANVLGINLNVPISLNVVLNHCGKKVPS 122
Cdd:cd01958   2 PTCpRDALKLGVCANVLGLSLLLLgtPAVQPCCPLIGGLADLDAAVCLCTAIKANILGISINIPVALSLLLNSCGRNVPP 81


                ....
gi 15237975 123 GFKC 126
Cdd:cd01958  82 GFTC 85
 
Name Accession Description Interval E-value
HPS_like cd01958
HPS_like: Hydrophobic Protein from Soybean (HPS)-like subfamily; composed of proteins with ...
 46-126 2.50e-25

HPS_like: Hydrophobic Protein from Soybean (HPS)-like subfamily; composed of proteins with similarity to HPS, a small hydrophobic protein with unknown function related to cereal-type alpha-amylase inhibitors and lipid transfer proteins. In addition to HPS, members of this subfamily include a hybrid proline-rich protein (HyPRP) from maize, a dark-inducible protein (LeDI-2) from Lithospermum erythrorhizon, maize ZRP3 protein, and rice RcC3 protein. HyPRP is an embryo-specific protein that contains an N-terminal proline-rich domain and a C-terminal HPS-like cysteine-rich domain. It has been suggested that HyPRP may be involved in the stability and defense of the developing embryo. LeDI-2 is a root-specific protein that may be involved in regulating the biosynthesis of shikonin derivatives in L. erythrorhizon. Maize ZRP3 and rice RcC3 are root-specific proteins whose functions are yet to be determined. It has been reported that ZRP3 largely accumulates in a distinct subset of cortical cells.


Pssm-ID: 238924  Cd Length: 85  Bit Score: 91.24  E-value: 2.50e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237975  46 PTC-KDALKLKVCANVLDLVKVSL--PPTSNCCALIKGLVDLEAAVCLCTALKANVLGINLNVPISLNVVLNHCGKKVPS 122
Cdd:cd01958   2 PTCpRDALKLGVCANVLGLSLLLLgtPAVQPCCPLIGGLADLDAAVCLCTAIKANILGISINIPVALSLLLNSCGRNVPP 81


                ....
gi 15237975 123 GFKC 126
Cdd:cd01958  82 GFTC 85
Hydrophob_seed pfam14547
Hydrophobic seed protein; This domain has a four-helix bundle structure. It contains four ...
 47-127 4.46e-18

Hydrophobic seed protein; This domain has a four-helix bundle structure. It contains four disulfide bonds, of which three function to keep the C- and N-terminal parts of the molecule in place.


Pssm-ID: 434033  Cd Length: 85  Bit Score: 72.86  E-value: 4.46e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237975    47 TC-KDALKLKVCANVLDLVKVSL--PPTSNCCALIKGLVDLEAAVCLCTALKANVLG-INLNVPISLNVVLNHCGKKVPS 122
Cdd:pfam14547   1 TCpRDALKLGACVNVLGLINITLgdQRASPCCTLVRGLADADAAACLCTTVRARLLNlLPITIPIALNLLLRACGRRPPP 80


                  ....*
gi 15237975   123 GFKCA 127
Cdd:pfam14547  81 GFTCP 85
AAI smart00499
Plant lipid transfer protein / seed storage protein / trypsin-alpha amylase inhibitor domain ...
 50-123 1.67e-06

Plant lipid transfer protein / seed storage protein / trypsin-alpha amylase inhibitor domain family;


Pssm-ID: 214698  Cd Length: 79  Bit Score: 43.14  E-value: 1.67e-06
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15237975     50 DALKLKVCANVLDLVKVSLPPTSNCCALIKGLVDleaAVCLCTALKANVLGINLN---VPISLNVVLNHCGKKVPSG 123
Cdd:smart00499   4 VLLQLAPCLSYLVGGSRGAPPSQQCCSQLRGLNS---AQCRCLALRAAVLGILEIpglNAQNAASLPSACGVPPPYT 77
 
Name Accession Description Interval E-value
HPS_like cd01958
HPS_like: Hydrophobic Protein from Soybean (HPS)-like subfamily; composed of proteins with ...
 46-126 2.50e-25

HPS_like: Hydrophobic Protein from Soybean (HPS)-like subfamily; composed of proteins with similarity to HPS, a small hydrophobic protein with unknown function related to cereal-type alpha-amylase inhibitors and lipid transfer proteins. In addition to HPS, members of this subfamily include a hybrid proline-rich protein (HyPRP) from maize, a dark-inducible protein (LeDI-2) from Lithospermum erythrorhizon, maize ZRP3 protein, and rice RcC3 protein. HyPRP is an embryo-specific protein that contains an N-terminal proline-rich domain and a C-terminal HPS-like cysteine-rich domain. It has been suggested that HyPRP may be involved in the stability and defense of the developing embryo. LeDI-2 is a root-specific protein that may be involved in regulating the biosynthesis of shikonin derivatives in L. erythrorhizon. Maize ZRP3 and rice RcC3 are root-specific proteins whose functions are yet to be determined. It has been reported that ZRP3 largely accumulates in a distinct subset of cortical cells.


Pssm-ID: 238924  Cd Length: 85  Bit Score: 91.24  E-value: 2.50e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237975  46 PTC-KDALKLKVCANVLDLVKVSL--PPTSNCCALIKGLVDLEAAVCLCTALKANVLGINLNVPISLNVVLNHCGKKVPS 122
Cdd:cd01958   2 PTCpRDALKLGVCANVLGLSLLLLgtPAVQPCCPLIGGLADLDAAVCLCTAIKANILGISINIPVALSLLLNSCGRNVPP 81


                ....
gi 15237975 123 GFKC 126
Cdd:cd01958  82 GFTC 85
Hydrophob_seed pfam14547
Hydrophobic seed protein; This domain has a four-helix bundle structure. It contains four ...
 47-127 4.46e-18

Hydrophobic seed protein; This domain has a four-helix bundle structure. It contains four disulfide bonds, of which three function to keep the C- and N-terminal parts of the molecule in place.


Pssm-ID: 434033  Cd Length: 85  Bit Score: 72.86  E-value: 4.46e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237975    47 TC-KDALKLKVCANVLDLVKVSL--PPTSNCCALIKGLVDLEAAVCLCTALKANVLG-INLNVPISLNVVLNHCGKKVPS 122
Cdd:pfam14547   1 TCpRDALKLGACVNVLGLINITLgdQRASPCCTLVRGLADADAAACLCTTVRARLLNlLPITIPIALNLLLRACGRRPPP 80


                  ....*
gi 15237975   123 GFKCA 127
Cdd:pfam14547  81 GFTCP 85
Tryp_alpha_amyl pfam00234
Protease inhibitor/seed storage/LTP family; This family is composed of trypsin-alpha amylase ...
 50-126 8.04e-12

Protease inhibitor/seed storage/LTP family; This family is composed of trypsin-alpha amylase inhibitors, seed storage proteins and lipid transfer proteins from plants.


Pssm-ID: 425543  Cd Length: 74  Bit Score: 56.42  E-value: 8.04e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15237975    50 DALKLKVCANVLdlVKVSLPPTSNCCALIKGLvdleAAVCLCTALKANVLGINLNVPISLNVVLNHCGKKVPSGFKC 126
Cdd:pfam00234   4 VLLCLAPCLGYL--QGGCQVPSQQCCSQLRQL----QAQCRCTAIRAIVLGIEGINPQAAASLPSMCGVNVPYGIDC 74
AAI smart00499
Plant lipid transfer protein / seed storage protein / trypsin-alpha amylase inhibitor domain ...
 50-123 1.67e-06

Plant lipid transfer protein / seed storage protein / trypsin-alpha amylase inhibitor domain family;


Pssm-ID: 214698  Cd Length: 79  Bit Score: 43.14  E-value: 1.67e-06
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15237975     50 DALKLKVCANVLDLVKVSLPPTSNCCALIKGLVDleaAVCLCTALKANVLGINLN---VPISLNVVLNHCGKKVPSG 123
Cdd:smart00499   4 VLLQLAPCLSYLVGGSRGAPPSQQCCSQLRGLNS---AQCRCLALRAAVLGILEIpglNAQNAASLPSACGVPPPYT 77
LTP_2 pfam14368
Probable lipid transfer; The members of this family are probably involved in lipid transfer. ...
 46-126 6.63e-04

Probable lipid transfer; The members of this family are probably involved in lipid transfer. The family has several highly conserved cysteines, paired in various ways.


Pssm-ID: 433909  Cd Length: 100  Bit Score: 36.69  E-value: 6.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237975    46 PTCKDALKLKV--CANVLDLVKVSLPPTSNCCALIKGLVDLEAAvCLCTALKANVL---GINLNVPISLNVVlnhCGKKV 120
Cdd:pfam14368  19 ASCTLSMLSGLspCLPYLTGTPAATAPSPACCGALKSAVSTDVT-CLCALVTAPLPigfPINVTRALALPRA---CGVKT 94


                  ....*.
gi 15237975   121 PSGFKC 126
Cdd:pfam14368  95 PPSSKC 100
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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