|
Name |
Accession |
Description |
Interval |
E-value |
| PLN03210 |
PLN03210 |
Resistant to P. syringae 6; Provisional |
13-1140 |
1.54e-102 |
|
Resistant to P. syringae 6; Provisional
Pssm-ID: 215633 [Multi-domain] Cd Length: 1153 Bit Score: 351.87 E-value: 1.54e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 13 VFINFRGDELRKTFISHLHKRLQRDGINAFIDSD----EAVGEELKnlfKRIENSEIALAVLSSRYTESHWCLQELVKMM 88
Cdd:PLN03210 15 VFPSFSGEDVRITFLSHFLKELDRKLIIAFKDNEiersQSLDPELK---QAIRDSRIAVVVFSKNYASSSWCLNELLEIV 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 89 ECsmkgegcNKKL--LVIPIFYKLKIDTVKELDGDFGRNLwdlwrKPGCGRDRDSRIVKWNEALKYFlsRNALVFSETG- 165
Cdd:PLN03210 92 RC-------KEELgqLVIPVFYGLDPSHVRKQTGDFGEAF-----EKTCQNKTEDEKIQWKQALTDV--ANILGYHSQNw 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 166 -KEEEFVSTIATHVknaLSKItpqrgenpkpqkgagNPKPQKILSRAANItepEDQrLKQLAVKLNVEcnDNETRIVEVV 244
Cdd:PLN03210 158 pNEAKMIEEIANDV---LGKL---------------NLTPSNDFEDFVGI---EDH-IAKMSSLLHLE--SEEVRMVGIW 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 245 GMPGIGKTYLAKKLFAKLKKKINHCVFIE---FKREMSAEQGSE--------WLQKRLVEGLLDIQDcTDTNALEVWKDS 313
Cdd:PLN03210 214 GSSGIGKTTIARALFSRLSRQFQSSVFIDrafISKSMEIYSSANpddynmklHLQRAFLSEILDKKD-IKIYHLGAMEER 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 314 LIDKKVVIVFDDVSDKkQISEPLKGICDWIKKGSMIVITTRDKSLTEGLVTD-LYEVPGLNERDGLELF-RAQVCCNIEG 391
Cdd:PLN03210 293 LKHRKVLIFIDDLDDQ-DVLDALAGQTQWFGSGSRIIVITKDKHFLRAHGIDhIYEVCLPSNELALEMFcRSAFKKNSPP 371
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 392 N-FMELSRKfVDFARGN-PLALEEFGKELRGKDEAHWETRLGTLAQHSNPTIREKLRSSYDELNEQQKDA-FLDIAYFFR 468
Cdd:PLN03210 372 DgFMELASE-VALRAGNlPLGLNVLGSYLRGRDKEDWMDMLPRLRNGLDGKIEKTLRVSYDGLNNKKDKAiFRHIACLFN 450
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 469 SQDESYVRSLLdsydpesAESGQE----FRDLADKFLIGVCDGRVEMHDLLFTMAKEIVEATAEK--SRLLLSSCAELKn 542
Cdd:PLN03210 451 GEKVNDIKLLL-------ANSDLDvnigLKNLVDKSLIHVREDIVEMHSLLQEMGKEIVRAQSNEpgEREFLVDAKDIC- 522
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 543 kELSLDQQGRDKVRGIVLDMSEMEEKPLKRAVFVGMSSLRYLKVYSSlcPTHSKTECKLHLPDGLEF--PKdniVRCLHW 620
Cdd:PLN03210 523 -DVLEDNTGTKKVLGITLDIDEIDELHIHENAFKGMRNLLFLKFYTK--KWDQKKEVRWHLPEGFDYlpPK---LRLLRW 596
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 621 VKFPGTELPPDFYPNNLIDLRLPYSNITTLWSCTKVAPNLKWVDLSHSSNLNSLMGLSEAPNLLRLNLEGCTSLKELPDE 700
Cdd:PLN03210 597 DKYPLRCMPSNFRPENLVKLQMQGSKLEKLWDGVHSLTGLRNIDLRGSKNLKEIPDLSMATNLETLKLSDCSSLVELPSS 676
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 701 MKDMTNLVFLNLRGCTSLLSLPK-ITTNSLKTLILSGCSSFQTFEVISEHLESLYLNGTEING----------------- 762
Cdd:PLN03210 677 IQYLNKLEDLDMSRCENLEILPTgINLKSLYRLNLSGCSRLKSFPDISTNISWLDLDETAIEEfpsnlrlenldelilce 756
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 763 -------------------------------------LPPAIGNLHRLIFLNLKDCKNLATLPDCLgELKSLQELKLSRC 805
Cdd:PLN03210 757 mkseklwervqpltplmtmlspsltrlflsdipslveLPSSIQNLHKLEHLEIENCINLETLPTGI-NLESLESLDLSGC 835
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 806 SKLKIFPDVTAKMESllvLLLDGTSIAELPCSIFHLSSLRRLCLSRNDNIRTLRFDMGHMFHLKWLELKYCKNLTSlpil 885
Cdd:PLN03210 836 SRLRTFPDISTNISD---LNLSRTGIEEVPWWIEKFSNLSFLDMNGCNNLQRVSLNISKLKHLETVDFSDCGALTE---- 908
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 886 ppnlqclnahgcTSLRTvaSPQTLPTPTEQIHSTF------IFTNCHELEQVsknAIIsyvqkksklmsadrySPDFVYK 959
Cdd:PLN03210 909 ------------ASWNG--SPSEVAMATDNIHSKLpstvciNFINCFNLDQE---ALL---------------QQQSIFK 956
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 960 SLIgtcFPGCEIPAWFNHQALGSVLI-LELPQAWNSSRIIGIALCVVVSFKEYRDQNSSLQVQCTCEFTNvslsqesfmv 1038
Cdd:PLN03210 957 QLI---LSGEEVPSYFTHRTTGASLTnIPLLHISPCQPFFRFRACAVVDSESFFIISVSFDIQVCCRFID---------- 1023
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 1039 ggwsEQGDETHTVESDHIFIGYTTLLNIK--------NRQQFPLAT----EISLRFQVTNGTSEVekcKVIKCGFSLvye 1106
Cdd:PLN03210 1024 ----RLGNHFDSPYQPHVFSVTKKGSHLVifdccfplNEDNAPLAElnydHVDIQFRLTNKNSQL---KLKGCGIRL--- 1093
|
1210 1220 1230
....*....|....*....|....*....|....
gi 15242338 1107 pNEADSTSWKETPRMEDNRQDRRIsFKTGEGDDC 1140
Cdd:PLN03210 1094 -SEDDSSLNNTLPNVEEADDDNPV-NGSEHWEDC 1125
|
|
| TIR |
smart00255 |
Toll - interleukin 1 - resistance; |
10-152 |
3.71e-33 |
|
Toll - interleukin 1 - resistance;
Pssm-ID: 214587 [Multi-domain] Cd Length: 140 Bit Score: 125.13 E-value: 3.71e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 10 EPQVFINFRG-DELRKTFISHLHKRLQRDGINAFIDSDEAVGEELKNLFKRIENSEIALAVLSSRYTESHWCLQELVKMM 88
Cdd:smart00255 1 EYDVFISYSGkEDVRNEFLSHLLEKLRGYGLCVFIDDFEPGGGDLEEIDEAIEKSRIAIVVLSPNYAESEWCLDELVAAL 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15242338 89 ECsMKGEGCNKkllVIPIFYKLKIDTVKELDGDFGRNLWDLWRKpgcgRDRDSRIVKWNEALKY 152
Cdd:smart00255 81 EN-ALEEGGLR---VIPIFYEVIPSDVRKQPGKFRKVFKKNYLK----WPEDEKEQFWKKALYA 136
|
|
| TIR |
pfam01582 |
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ... |
12-185 |
6.81e-30 |
|
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.
Pssm-ID: 396246 [Multi-domain] Cd Length: 165 Bit Score: 116.70 E-value: 6.81e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 12 QVFINFRGDELRKTFISHLHKRLQRDGINAFIDSD-----EAVGEELKnlfKRIENSEIALAVLSSRYTESHWCLQELVK 86
Cdd:pfam01582 2 DVFLSFRGSDTREWFVSHLLKELKQKGIKLFIDDRdlepgEAIAPELL---SAIEKSRRSVVVLSPNYASSGWCLDELVK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 87 MMECSMKGegcnkKLLVIPIFYKLKIDTVKELDGDFGRNLwdlwrKPGCGRDRDSRIVKWNEALKYFlsRNALVFSETGK 166
Cdd:pfam01582 79 ILECALDL-----GQKVIPIFYEVDPSDVRKQTGSFGKAF-----KKHKKVLTEEKVLKWRGALNEV--ANIWHSKSVSD 146
|
170
....*....|....*....
gi 15242338 167 EEEFVSTIATHVKNALSKI 185
Cdd:pfam01582 147 ESKFWKKIAYDISNKLNGT 165
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
626-896 |
4.09e-27 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 115.80 E-value: 4.09e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 626 TELPPDFYPNNLIDLRLPYSNITTLWSCTKVAPNLKWVDLSHSSNLNSLMGLSEAPNLLRLNLEGCTSLKELPDEMKDMT 705
Cdd:COG4886 17 LLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLT 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 706 NLVFLNLRGCTSLLSLPKittnsLKTLILSGCSSFQTFEVISE--HLESLYLNGTEINGLPPAIGNLHRLIFLNLKDCKn 783
Cdd:COG4886 97 NLTELDLSGNEELSNLTN-----LESLDLSGNQLTDLPEELANltNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQ- 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 784 LATLPDCLGELKSLQELKLSRCsKLKIFPDVTAKMESLLVLLLDGTSIAELPCSIFHLSSLRRLCLSRNdNIRTLRfDMG 863
Cdd:COG4886 171 LTDLPEELGNLTNLKELDLSNN-QITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNN-QLTDLP-ELG 247
|
250 260 270
....*....|....*....|....*....|....*
gi 15242338 864 HMFHLKWLELKYCKnLTSLPILP--PNLQCLNAHG 896
Cdd:COG4886 248 NLTNLEELDLSNNQ-LTDLPPLAnlTNLKTLDLSN 281
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
749-874 |
1.15e-03 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 41.70 E-value: 1.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 749 HLESLYLNG---TEINGLppaiGNLHRLIFLNLkDCKNLATLPDcLGELKSLQELKLSR---CSKLKIFPD---VTAKME 819
Cdd:cd21340 47 NLTHLYLQNnqiEKIENL----ENLVNLKKLYL-GGNRISVVEG-LENLTNLEELHIENqrlPPGEKLTFDprsLAALSN 120
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 15242338 820 SLLVLLLDGTSIAELPCsIFHLSSLRRLCLSRN--DNIRTLRFDMGHMFHLKWLELK 874
Cdd:cd21340 121 SLRVLNISGNNIDSLEP-LAPLRNLEQLDASNNqiSDLEELLDLLSSWPSLRELDLT 176
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN03210 |
PLN03210 |
Resistant to P. syringae 6; Provisional |
13-1140 |
1.54e-102 |
|
Resistant to P. syringae 6; Provisional
Pssm-ID: 215633 [Multi-domain] Cd Length: 1153 Bit Score: 351.87 E-value: 1.54e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 13 VFINFRGDELRKTFISHLHKRLQRDGINAFIDSD----EAVGEELKnlfKRIENSEIALAVLSSRYTESHWCLQELVKMM 88
Cdd:PLN03210 15 VFPSFSGEDVRITFLSHFLKELDRKLIIAFKDNEiersQSLDPELK---QAIRDSRIAVVVFSKNYASSSWCLNELLEIV 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 89 ECsmkgegcNKKL--LVIPIFYKLKIDTVKELDGDFGRNLwdlwrKPGCGRDRDSRIVKWNEALKYFlsRNALVFSETG- 165
Cdd:PLN03210 92 RC-------KEELgqLVIPVFYGLDPSHVRKQTGDFGEAF-----EKTCQNKTEDEKIQWKQALTDV--ANILGYHSQNw 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 166 -KEEEFVSTIATHVknaLSKItpqrgenpkpqkgagNPKPQKILSRAANItepEDQrLKQLAVKLNVEcnDNETRIVEVV 244
Cdd:PLN03210 158 pNEAKMIEEIANDV---LGKL---------------NLTPSNDFEDFVGI---EDH-IAKMSSLLHLE--SEEVRMVGIW 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 245 GMPGIGKTYLAKKLFAKLKKKINHCVFIE---FKREMSAEQGSE--------WLQKRLVEGLLDIQDcTDTNALEVWKDS 313
Cdd:PLN03210 214 GSSGIGKTTIARALFSRLSRQFQSSVFIDrafISKSMEIYSSANpddynmklHLQRAFLSEILDKKD-IKIYHLGAMEER 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 314 LIDKKVVIVFDDVSDKkQISEPLKGICDWIKKGSMIVITTRDKSLTEGLVTD-LYEVPGLNERDGLELF-RAQVCCNIEG 391
Cdd:PLN03210 293 LKHRKVLIFIDDLDDQ-DVLDALAGQTQWFGSGSRIIVITKDKHFLRAHGIDhIYEVCLPSNELALEMFcRSAFKKNSPP 371
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 392 N-FMELSRKfVDFARGN-PLALEEFGKELRGKDEAHWETRLGTLAQHSNPTIREKLRSSYDELNEQQKDA-FLDIAYFFR 468
Cdd:PLN03210 372 DgFMELASE-VALRAGNlPLGLNVLGSYLRGRDKEDWMDMLPRLRNGLDGKIEKTLRVSYDGLNNKKDKAiFRHIACLFN 450
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 469 SQDESYVRSLLdsydpesAESGQE----FRDLADKFLIGVCDGRVEMHDLLFTMAKEIVEATAEK--SRLLLSSCAELKn 542
Cdd:PLN03210 451 GEKVNDIKLLL-------ANSDLDvnigLKNLVDKSLIHVREDIVEMHSLLQEMGKEIVRAQSNEpgEREFLVDAKDIC- 522
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 543 kELSLDQQGRDKVRGIVLDMSEMEEKPLKRAVFVGMSSLRYLKVYSSlcPTHSKTECKLHLPDGLEF--PKdniVRCLHW 620
Cdd:PLN03210 523 -DVLEDNTGTKKVLGITLDIDEIDELHIHENAFKGMRNLLFLKFYTK--KWDQKKEVRWHLPEGFDYlpPK---LRLLRW 596
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 621 VKFPGTELPPDFYPNNLIDLRLPYSNITTLWSCTKVAPNLKWVDLSHSSNLNSLMGLSEAPNLLRLNLEGCTSLKELPDE 700
Cdd:PLN03210 597 DKYPLRCMPSNFRPENLVKLQMQGSKLEKLWDGVHSLTGLRNIDLRGSKNLKEIPDLSMATNLETLKLSDCSSLVELPSS 676
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 701 MKDMTNLVFLNLRGCTSLLSLPK-ITTNSLKTLILSGCSSFQTFEVISEHLESLYLNGTEING----------------- 762
Cdd:PLN03210 677 IQYLNKLEDLDMSRCENLEILPTgINLKSLYRLNLSGCSRLKSFPDISTNISWLDLDETAIEEfpsnlrlenldelilce 756
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 763 -------------------------------------LPPAIGNLHRLIFLNLKDCKNLATLPDCLgELKSLQELKLSRC 805
Cdd:PLN03210 757 mkseklwervqpltplmtmlspsltrlflsdipslveLPSSIQNLHKLEHLEIENCINLETLPTGI-NLESLESLDLSGC 835
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 806 SKLKIFPDVTAKMESllvLLLDGTSIAELPCSIFHLSSLRRLCLSRNDNIRTLRFDMGHMFHLKWLELKYCKNLTSlpil 885
Cdd:PLN03210 836 SRLRTFPDISTNISD---LNLSRTGIEEVPWWIEKFSNLSFLDMNGCNNLQRVSLNISKLKHLETVDFSDCGALTE---- 908
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 886 ppnlqclnahgcTSLRTvaSPQTLPTPTEQIHSTF------IFTNCHELEQVsknAIIsyvqkksklmsadrySPDFVYK 959
Cdd:PLN03210 909 ------------ASWNG--SPSEVAMATDNIHSKLpstvciNFINCFNLDQE---ALL---------------QQQSIFK 956
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 960 SLIgtcFPGCEIPAWFNHQALGSVLI-LELPQAWNSSRIIGIALCVVVSFKEYRDQNSSLQVQCTCEFTNvslsqesfmv 1038
Cdd:PLN03210 957 QLI---LSGEEVPSYFTHRTTGASLTnIPLLHISPCQPFFRFRACAVVDSESFFIISVSFDIQVCCRFID---------- 1023
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 1039 ggwsEQGDETHTVESDHIFIGYTTLLNIK--------NRQQFPLAT----EISLRFQVTNGTSEVekcKVIKCGFSLvye 1106
Cdd:PLN03210 1024 ----RLGNHFDSPYQPHVFSVTKKGSHLVifdccfplNEDNAPLAElnydHVDIQFRLTNKNSQL---KLKGCGIRL--- 1093
|
1210 1220 1230
....*....|....*....|....*....|....
gi 15242338 1107 pNEADSTSWKETPRMEDNRQDRRIsFKTGEGDDC 1140
Cdd:PLN03210 1094 -SEDDSSLNNTLPNVEEADDDNPV-NGSEHWEDC 1125
|
|
| TIR |
smart00255 |
Toll - interleukin 1 - resistance; |
10-152 |
3.71e-33 |
|
Toll - interleukin 1 - resistance;
Pssm-ID: 214587 [Multi-domain] Cd Length: 140 Bit Score: 125.13 E-value: 3.71e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 10 EPQVFINFRG-DELRKTFISHLHKRLQRDGINAFIDSDEAVGEELKNLFKRIENSEIALAVLSSRYTESHWCLQELVKMM 88
Cdd:smart00255 1 EYDVFISYSGkEDVRNEFLSHLLEKLRGYGLCVFIDDFEPGGGDLEEIDEAIEKSRIAIVVLSPNYAESEWCLDELVAAL 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15242338 89 ECsMKGEGCNKkllVIPIFYKLKIDTVKELDGDFGRNLWDLWRKpgcgRDRDSRIVKWNEALKY 152
Cdd:smart00255 81 EN-ALEEGGLR---VIPIFYEVIPSDVRKQPGKFRKVFKKNYLK----WPEDEKEQFWKKALYA 136
|
|
| TIR |
pfam01582 |
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ... |
12-185 |
6.81e-30 |
|
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.
Pssm-ID: 396246 [Multi-domain] Cd Length: 165 Bit Score: 116.70 E-value: 6.81e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 12 QVFINFRGDELRKTFISHLHKRLQRDGINAFIDSD-----EAVGEELKnlfKRIENSEIALAVLSSRYTESHWCLQELVK 86
Cdd:pfam01582 2 DVFLSFRGSDTREWFVSHLLKELKQKGIKLFIDDRdlepgEAIAPELL---SAIEKSRRSVVVLSPNYASSGWCLDELVK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 87 MMECSMKGegcnkKLLVIPIFYKLKIDTVKELDGDFGRNLwdlwrKPGCGRDRDSRIVKWNEALKYFlsRNALVFSETGK 166
Cdd:pfam01582 79 ILECALDL-----GQKVIPIFYEVDPSDVRKQTGSFGKAF-----KKHKKVLTEEKVLKWRGALNEV--ANIWHSKSVSD 146
|
170
....*....|....*....
gi 15242338 167 EEEFVSTIATHVKNALSKI 185
Cdd:pfam01582 147 ESKFWKKIAYDISNKLNGT 165
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
626-896 |
4.09e-27 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 115.80 E-value: 4.09e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 626 TELPPDFYPNNLIDLRLPYSNITTLWSCTKVAPNLKWVDLSHSSNLNSLMGLSEAPNLLRLNLEGCTSLKELPDEMKDMT 705
Cdd:COG4886 17 LLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLT 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 706 NLVFLNLRGCTSLLSLPKittnsLKTLILSGCSSFQTFEVISE--HLESLYLNGTEINGLPPAIGNLHRLIFLNLKDCKn 783
Cdd:COG4886 97 NLTELDLSGNEELSNLTN-----LESLDLSGNQLTDLPEELANltNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQ- 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 784 LATLPDCLGELKSLQELKLSRCsKLKIFPDVTAKMESLLVLLLDGTSIAELPCSIFHLSSLRRLCLSRNdNIRTLRfDMG 863
Cdd:COG4886 171 LTDLPEELGNLTNLKELDLSNN-QITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNN-QLTDLP-ELG 247
|
250 260 270
....*....|....*....|....*....|....*
gi 15242338 864 HMFHLKWLELKYCKnLTSLPILP--PNLQCLNAHG 896
Cdd:COG4886 248 NLTNLEELDLSNNQ-LTDLPPLAnlTNLKTLDLSN 281
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
626-803 |
6.69e-14 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 75.36 E-value: 6.69e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 626 TELPPDFYP-NNLIDLRLPYSNITTLWSCTKVAPNLKWVDLSHssnlNSLMGLSEA----PNLLRLNLEGcTSLKELPDE 700
Cdd:COG4886 126 TDLPEELANlTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSN----NQLTDLPEElgnlTNLKELDLSN-NQITDLPEP 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 701 MKDMTNLVFLNLRGC--TSL-LSLPKITtnSLKTLILSGCSsFQTFEVISE--HLESLYLNGTEINGLPPaIGNLHRLIF 775
Cdd:COG4886 201 LGNLTNLEELDLSGNqlTDLpEPLANLT--NLETLDLSNNQ-LTDLPELGNltNLEELDLSNNQLTDLPP-LANLTNLKT 276
|
170 180 190
....*....|....*....|....*....|..
gi 15242338 776 LNLKDCK----NLATLPDCLGELKSLQELKLS 803
Cdd:COG4886 277 LDLSNNQltdlKLKELELLLGLNSLLLLLLLL 308
|
|
| TIR_2 |
pfam13676 |
TIR domain; This is a family of Toll-like receptors. |
13-108 |
3.34e-11 |
|
TIR domain; This is a family of Toll-like receptors.
Pssm-ID: 463954 [Multi-domain] Cd Length: 118 Bit Score: 61.56 E-value: 3.34e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 13 VFINFRGDElrKTFISHLHKRLQRDGINAFIDS-DEAVGEELKN-LFKRIENSEIALAVLSSRYTESHWCLQELVKMMEC 90
Cdd:pfam13676 1 VFISYAGED--RAWAEWLADALEAAGYRVWLDRwDIRPGDDWVEeIEEAIENSDRVLVVLSPNYLESPWCRAEWEAALAD 78
|
90
....*....|....*...
gi 15242338 91 SMKGEGcnkkllVIPIFY 108
Cdd:pfam13676 79 PEGRKR------LIPVRL 90
|
|
| PLN03194 |
PLN03194 |
putative disease resistance protein; Provisional |
13-111 |
1.49e-10 |
|
putative disease resistance protein; Provisional
Pssm-ID: 215626 [Multi-domain] Cd Length: 187 Bit Score: 61.76 E-value: 1.49e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 13 VFINFRGDELRKTFISHLHKRLQRDGINAFIDSDE-AVGEEL-KNLFKRIENSEIALAVLSSRYTESHWCLQELVKMMEC 90
Cdd:PLN03194 29 VFINHRGIDTKRTIATLLYDHLSRLNLRPFLDNKNmKPGDKLfDKINSAIRNCKVGVAVFSPRYCESYFCLHELALIMES 108
|
90 100
....*....|....*....|.
gi 15242338 91 SMKgegcnkkllVIPIFYKLK 111
Cdd:PLN03194 109 KKR---------VIPIFCDVK 120
|
|
| NB-ARC |
pfam00931 |
NB-ARC domain; |
219-454 |
9.81e-10 |
|
NB-ARC domain;
Pssm-ID: 395745 [Multi-domain] Cd Length: 245 Bit Score: 60.47 E-value: 9.81e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 219 DQRLKQLAVKLNVECndnETRIVEVVGMPGIGKTYLAKKLFAKLKKKINHC-VFIEFKreMSAEQGSEWLQKRLVEGLL- 296
Cdd:pfam00931 2 EDMVEKVIGKLSEKD---EPGIVGIHGMGGVGKTTLAAQIFNDFDEVEGHFdSVAWVV--VSKTFTISTLQQTILQNLGl 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 297 ---DIQDCTDTNALEVWKDSLIDKKVVIVFDDVSDKKQISEPLKGICDWIKKGSMIViTTRDKSLTE--GLVTDLYEVPG 371
Cdd:pfam00931 77 sedDWDNKEEGELARKIRRALLTKRFLLVLDDVWDEEDWDKIGIPLPDRENGCRVLL-TTRSEEVAGrvGGPSDPHEVEL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 372 LNERDGLELFRAQV-------CCNIEgnfmELSRKFVDFARGNPLALEEFGKELRGKD-EAHWEtrlgtlaqHSNPTIRE 443
Cdd:pfam00931 156 LEPDEAWELFENKVfpktlgeCELLE----DVAKEIVEKCRGLPLALKVLGGLLSCKKtVEEWK--------HVYDVLQS 223
|
250
....*....|.
gi 15242338 444 KLRSSYDELNE 454
Cdd:pfam00931 224 ELKSNSYSLNS 234
|
|
| C-JID |
pfam20160 |
C-JID domain; C-terminal jelly roll/Ig-like domain (C-JID) was defined in cryogenic electron ... |
966-1010 |
5.07e-09 |
|
C-JID domain; C-terminal jelly roll/Ig-like domain (C-JID) was defined in cryogenic electron microscopy (cryoEM) structures of plant intracellular immune receptors containing Toll/interleukin-1 receptor (TIR, PF01582), nucleotide-binding (NB-ARC, PF00931) and leucine-rich repeat (LRR) domains (TIR-NLRs). Structurally, the C-JID core is represented by a beta-sandwich made up of 8 to 9 beta-strands. C-JID matches the so-called post LRR domain originally detected via a set of MEME motifs. The domain showed a strong distribution bias towards TIR-NLRs of dicotyledonous plant species despite broader taxonomic distribution of TIR-NLR in plant groups. Structure-function analyses of cryoEM structures suggest that C-JID domains play a role in substrate-recognition, such as binding to effector proteins from pathogens, and thus are involved in the initiation of signaling by TIR-NLR receptors. Presence of C-JID (or post-LRR) and its importance for the function of Arabidopsis TIR-NLR RPS4 that partners with RRS1 for effector recognition suggest that C-JID has additional functions.
Pssm-ID: 466313 Cd Length: 108 Bit Score: 55.15 E-value: 5.07e-09
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 15242338 966 FPGCEIPAWFNHQALGSVLILELPQAWNSSRIIGIALCVVVSFKE 1010
Cdd:pfam20160 1 LPGSQIPEWFNHQSTGSSISIKLPENWYNDNFLGFAVCAVGSLIP 45
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
659-852 |
7.05e-04 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 44.07 E-value: 7.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 659 NLKWVDLSHssnlNSLMGlsEAPNllrlNLEGCTSLKEL-----------PDEMKDMTNLVFLNLR-------------G 714
Cdd:PLN00113 213 SLKWIYLGY----NNLSG--EIPY----EIGGLTSLNHLdlvynnltgpiPSSLGNLKNLQYLFLYqnklsgpippsifS 282
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 715 CTSLLSLpKITTNSLKTLILSGCSSFQTFEVIseHLESLYLNGTeingLPPAIGNLHRLIFLNLKDCKNLATLPDCLGEL 794
Cdd:PLN00113 283 LQKLISL-DLSDNSLSGEIPELVIQLQNLEIL--HLFSNNFTGK----IPVALTSLPRLQVLQLWSNKFSGEIPKNLGKH 355
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 15242338 795 KSLQELKLSRCSKLKIFPDVTAKMESLLVLLLDGTSI-AELPCSIFHLSSLRRLCLSRN 852
Cdd:PLN00113 356 NNLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLeGEIPKSLGACRSLRRVRLQDN 414
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
749-874 |
1.15e-03 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 41.70 E-value: 1.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 749 HLESLYLNG---TEINGLppaiGNLHRLIFLNLkDCKNLATLPDcLGELKSLQELKLSR---CSKLKIFPD---VTAKME 819
Cdd:cd21340 47 NLTHLYLQNnqiEKIENL----ENLVNLKKLYL-GGNRISVVEG-LENLTNLEELHIENqrlPPGEKLTFDprsLAALSN 120
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 15242338 820 SLLVLLLDGTSIAELPCsIFHLSSLRRLCLSRN--DNIRTLRFDMGHMFHLKWLELK 874
Cdd:cd21340 121 SLRVLNISGNNIDSLEP-LAPLRNLEQLDASNNqiSDLEELLDLLSSWPSLRELDLT 176
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
635-847 |
1.54e-03 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 42.91 E-value: 1.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 635 NNLIDLRLPySNITTLWSctkvapNLKWVDLShSSNLNSLMGLSEAPNLLRLNLEGCTSLKELPDEMKDMTNLVFLNLRG 714
Cdd:PLN00113 102 NNQLSGPIP-DDIFTTSS------SLRYLNLS-NNNFTGSIPRGSIPNLETLDLSNNMLSGEIPNDIGSFSSLKVLDLGG 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 715 CTSLLSLPKITTN--SLKTLIL-----------------------------SGCSSFQTFEVIS-EHLESLYLNGTeiNG 762
Cdd:PLN00113 174 NVLVGKIPNSLTNltSLEFLTLasnqlvgqiprelgqmkslkwiylgynnlSGEIPYEIGGLTSlNHLDLVYNNLT--GP 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 763 LPPAIGNLHRLIFLNLKDCKNLATLPDCLGELKSLQELKLSRCSKLKIFPDVTAKMESLLVL-LLDGTSIAELPCSifhL 841
Cdd:PLN00113 252 IPSSLGNLKNLQYLFLYQNKLSGPIPPSIFSLQKLISLDLSDNSLSGEIPELVIQLQNLEILhLFSNNFTGKIPVA---L 328
|
....*.
gi 15242338 842 SSLRRL 847
Cdd:PLN00113 329 TSLPRL 334
|
|
| LRR_3 |
pfam07725 |
Leucine Rich Repeat; This Pfam entry includes some LRRs that fail to be detected by the ... |
636-655 |
1.89e-03 |
|
Leucine Rich Repeat; This Pfam entry includes some LRRs that fail to be detected by the pfam00560 model.
Pssm-ID: 429621 [Multi-domain] Cd Length: 20 Bit Score: 36.55 E-value: 1.89e-03
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
657-833 |
4.92e-03 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 39.77 E-value: 4.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 657 APNLKWVDLSHSsNLNSLMGLSEAPNLLRL-----------NLEGCTSLKEL-------PDEMKdmtnLVFlnlrGCTSL 718
Cdd:cd21340 45 LTNLTHLYLQNN-QIEKIENLENLVNLKKLylggnrisvveGLENLTNLEELhienqrlPPGEK----LTF----DPRSL 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242338 719 LSLpkitTNSLKTLILSGCssfqtfeviseHLESLYlngteinglppAIGNLHRLIFLNLKDCK--NLATLPDCLGELKS 796
Cdd:cd21340 116 AAL----SNSLRVLNISGN-----------NIDSLE-----------PLAPLRNLEQLDASNNQisDLEELLDLLSSWPS 169
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 15242338 797 LQELKLS---RCSKLKIFPDVTAKMESLLVllLDGTSIAE 833
Cdd:cd21340 170 LRELDLTgnpVCKKPKYRDKIILASKSLEV--LDGKEITD 207
|
|
| |
