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Conserved domains on  [gi|22327362|ref|NP_198419|]
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zinc metalloproteinase-like protein [Arabidopsis thaliana]

Protein Classification

SprT family zinc-dependent metalloprotease( domain architecture ID 10996102)

SprT family zinc-dependent metalloprotease, which contains an HExxH motif characteristic of zinc metallopeptidases

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
YgjP-like super family cl19237
YgjP-like, metallopeptidase domain; This is a conserved domain containing the catalytic ...
144-329 1.59e-64

YgjP-like, metallopeptidase domain; This is a conserved domain containing the catalytic zinc-metallopeptidase (HExxH) catalytic motif. Proteins containing this domain are found in some archaebacteria, as well as Helicobacter pylori. The proteins are 190-240 amino acids long, with the C terminus being the most conserved region, containing three conserved histidines. This domain is found in YgjP from E. coli, a predicted metal-dependent hydrolase that hydrolyses UTP to UMP and diphosphate in vitro; and in MJ0123 from Methanocaldococcus jannaschii (also referred to as projannalysin).


The actual alignment was detected with superfamily member pfam08325:

Pssm-ID: 473153  Cd Length: 190  Bit Score: 209.88  E-value: 1.59e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22327362   144 FGDFRTLQLPgieLNPPPSAALKRMHMLAADpgIIAVMNKHRWRVGIMTELAPVGYVgvsprcLLGFNKNQGEEISLRLR 223
Cdd:pfam08325   1 PKVGNIKVLK---RKPNPSRALELLKRIARD--VRPIMKEHRFRVGLLTEFYPKNRN------LLGLNVNKGEKIELRLR 69
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22327362   224 TD-DLKGFRKYQSIKKTLLHELAHMVYTEHDEKFYALDSQLNKEAESLDW------TKSRGHTLNGTKFINDDDEEDYFF 296
Cdd:pfam08325  70 TDsDDKGFLPYESIMGTLLHELAHNVHGPHDAKFYALLDQLRKEYEELDQkgygdgFLKTGRRLGGAGVRNSPNEREANG 149
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 22327362   297 DENE-----TVSQRLGGNQ--SDNLGNARESSVAAAYRRL 329
Cdd:pfam08325 150 RVLGrtgiaGGGQRLGGNSpiSRSGLSPRELAASAAERRL 189
PUB_WLM cd10463
PNGase/UBA or UBX (PUB) domain of the Wss1p-like metalloprotease (WLM) family; The PUB domain ...
497-597 3.52e-44

PNGase/UBA or UBX (PUB) domain of the Wss1p-like metalloprotease (WLM) family; The PUB domain functions as a p97 (also known as valosin-containing protein or VCP) adaptor by interacting with the D1 and/or D2 ATPase domains. The type II AAA+ ATPase p97 is involved in a variety of cellular processes such as the deglycosylation of ERAD substrates, membrane fusion, transcription factor activation and cell cycle regulation through differential binding to specific adaptor proteins. WLM domains are found mostly in plant proteins, belonging to the Zincin-like superfamily of Zn-dependent peptidases that are linked to the ubiquitin signaling pathway through its fusion with the ubiquitin-binding PUB, ubiquitin-like, and Little Finger domains. More specifically, genetic evidence implicates the WLM family in de-SUMOylation.


:

Pssm-ID: 198421  Cd Length: 96  Bit Score: 152.54  E-value: 3.52e-44
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22327362 497 AIKALRNEVSPGQATTVLQMLLKIVRNIIEQPNEMKFKRLRKGNPAIKRNILNFPAAVEILSVVGFVDEMVSestgAQEP 576
Cdd:cd10463   1 ALAALRSAVSPAEAVSALQTLFKILGNAIEHPNEDKFRRLRKSNPAFQRRVARFPGAVELLLAAGFAEEGVS----GPDT 76
                        90       100
                ....*....|....*....|.
gi 22327362 577 YLVLkRNDPGLLWIAKSMIEE 597
Cdd:cd10463  77 YLLL-RNDPGLLWLAKSSVEE 96
 
Name Accession Description Interval E-value
WLM pfam08325
WLM domain; This is a predicted metallopeptidase domain called WLM (Wss1p-like ...
144-329 1.59e-64

WLM domain; This is a predicted metallopeptidase domain called WLM (Wss1p-like metalloproteases). These are linked to the Ub-system by virtue of fusions with the UB-binding PUG (PUB), Ub-like, and Little Finger domains. More specifically, genetic evidence implicates the WLM family in de-SUMOylation.


Pssm-ID: 311984  Cd Length: 190  Bit Score: 209.88  E-value: 1.59e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22327362   144 FGDFRTLQLPgieLNPPPSAALKRMHMLAADpgIIAVMNKHRWRVGIMTELAPVGYVgvsprcLLGFNKNQGEEISLRLR 223
Cdd:pfam08325   1 PKVGNIKVLK---RKPNPSRALELLKRIARD--VRPIMKEHRFRVGLLTEFYPKNRN------LLGLNVNKGEKIELRLR 69
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22327362   224 TD-DLKGFRKYQSIKKTLLHELAHMVYTEHDEKFYALDSQLNKEAESLDW------TKSRGHTLNGTKFINDDDEEDYFF 296
Cdd:pfam08325  70 TDsDDKGFLPYESIMGTLLHELAHNVHGPHDAKFYALLDQLRKEYEELDQkgygdgFLKTGRRLGGAGVRNSPNEREANG 149
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 22327362   297 DENE-----TVSQRLGGNQ--SDNLGNARESSVAAAYRRL 329
Cdd:pfam08325 150 RVLGrtgiaGGGQRLGGNSpiSRSGLSPRELAASAAERRL 189
PUB_WLM cd10463
PNGase/UBA or UBX (PUB) domain of the Wss1p-like metalloprotease (WLM) family; The PUB domain ...
497-597 3.52e-44

PNGase/UBA or UBX (PUB) domain of the Wss1p-like metalloprotease (WLM) family; The PUB domain functions as a p97 (also known as valosin-containing protein or VCP) adaptor by interacting with the D1 and/or D2 ATPase domains. The type II AAA+ ATPase p97 is involved in a variety of cellular processes such as the deglycosylation of ERAD substrates, membrane fusion, transcription factor activation and cell cycle regulation through differential binding to specific adaptor proteins. WLM domains are found mostly in plant proteins, belonging to the Zincin-like superfamily of Zn-dependent peptidases that are linked to the ubiquitin signaling pathway through its fusion with the ubiquitin-binding PUB, ubiquitin-like, and Little Finger domains. More specifically, genetic evidence implicates the WLM family in de-SUMOylation.


Pssm-ID: 198421  Cd Length: 96  Bit Score: 152.54  E-value: 3.52e-44
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22327362 497 AIKALRNEVSPGQATTVLQMLLKIVRNIIEQPNEMKFKRLRKGNPAIKRNILNFPAAVEILSVVGFVDEMVSestgAQEP 576
Cdd:cd10463   1 ALAALRSAVSPAEAVSALQTLFKILGNAIEHPNEDKFRRLRKSNPAFQRRVARFPGAVELLLAAGFAEEGVS----GPDT 76
                        90       100
                ....*....|....*....|.
gi 22327362 577 YLVLkRNDPGLLWIAKSMIEE 597
Cdd:cd10463  77 YLLL-RNDPGLLWLAKSSVEE 96
PUB pfam09409
PUB domain; The PUB (also known as PUG) domain is found in peptide N-glycanase where it ...
509-593 2.21e-15

PUB domain; The PUB (also known as PUG) domain is found in peptide N-glycanase where it functions as a AAA ATPase binding domain. This domain is also found on other proteins linked to the ubiquitin-proteasome system.


Pssm-ID: 462790  Cd Length: 80  Bit Score: 71.15  E-value: 2.21e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22327362   509 QATTVLQMLLKIVRNIIEQPNEMKFKRLRKGNPAIKRNILNFPAAVEILSVVGFVDEmvsestgAQEPYLVLKRNDPGLL 588
Cdd:pfam09409   3 KVKEALETLLKYLNNILSNPNEEKYRKIRLSNKAFQEKVLPLEGALELLLAIGFEKE-------DEEEFLLLEEESLKQL 75

                  ....*
gi 22327362   589 WIAKS 593
Cdd:pfam09409  76 AVLLE 80
PUG smart00580
domain in protein kinases, N-glycanases and other nuclear proteins;
513-581 7.74e-12

domain in protein kinases, N-glycanases and other nuclear proteins;


Pssm-ID: 197798  Cd Length: 57  Bit Score: 60.39  E-value: 7.74e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 22327362    513 VLQMLLKIVRNIIEQPNEMKfkrlrkGNPAIKRNILNFPAAVEILSVVGFVDEMVSestgaqEPYLVLK 581
Cdd:smart00580   1 SVRDLLRALRNILHHPREEK------GNPAIKERLGPVPGGFELYFTVGFPRLLIS------EVYTLPK 57
 
Name Accession Description Interval E-value
WLM pfam08325
WLM domain; This is a predicted metallopeptidase domain called WLM (Wss1p-like ...
144-329 1.59e-64

WLM domain; This is a predicted metallopeptidase domain called WLM (Wss1p-like metalloproteases). These are linked to the Ub-system by virtue of fusions with the UB-binding PUG (PUB), Ub-like, and Little Finger domains. More specifically, genetic evidence implicates the WLM family in de-SUMOylation.


Pssm-ID: 311984  Cd Length: 190  Bit Score: 209.88  E-value: 1.59e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22327362   144 FGDFRTLQLPgieLNPPPSAALKRMHMLAADpgIIAVMNKHRWRVGIMTELAPVGYVgvsprcLLGFNKNQGEEISLRLR 223
Cdd:pfam08325   1 PKVGNIKVLK---RKPNPSRALELLKRIARD--VRPIMKEHRFRVGLLTEFYPKNRN------LLGLNVNKGEKIELRLR 69
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22327362   224 TD-DLKGFRKYQSIKKTLLHELAHMVYTEHDEKFYALDSQLNKEAESLDW------TKSRGHTLNGTKFINDDDEEDYFF 296
Cdd:pfam08325  70 TDsDDKGFLPYESIMGTLLHELAHNVHGPHDAKFYALLDQLRKEYEELDQkgygdgFLKTGRRLGGAGVRNSPNEREANG 149
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 22327362   297 DENE-----TVSQRLGGNQ--SDNLGNARESSVAAAYRRL 329
Cdd:pfam08325 150 RVLGrtgiaGGGQRLGGNSpiSRSGLSPRELAASAAERRL 189
PUB_WLM cd10463
PNGase/UBA or UBX (PUB) domain of the Wss1p-like metalloprotease (WLM) family; The PUB domain ...
497-597 3.52e-44

PNGase/UBA or UBX (PUB) domain of the Wss1p-like metalloprotease (WLM) family; The PUB domain functions as a p97 (also known as valosin-containing protein or VCP) adaptor by interacting with the D1 and/or D2 ATPase domains. The type II AAA+ ATPase p97 is involved in a variety of cellular processes such as the deglycosylation of ERAD substrates, membrane fusion, transcription factor activation and cell cycle regulation through differential binding to specific adaptor proteins. WLM domains are found mostly in plant proteins, belonging to the Zincin-like superfamily of Zn-dependent peptidases that are linked to the ubiquitin signaling pathway through its fusion with the ubiquitin-binding PUB, ubiquitin-like, and Little Finger domains. More specifically, genetic evidence implicates the WLM family in de-SUMOylation.


Pssm-ID: 198421  Cd Length: 96  Bit Score: 152.54  E-value: 3.52e-44
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22327362 497 AIKALRNEVSPGQATTVLQMLLKIVRNIIEQPNEMKFKRLRKGNPAIKRNILNFPAAVEILSVVGFVDEMVSestgAQEP 576
Cdd:cd10463   1 ALAALRSAVSPAEAVSALQTLFKILGNAIEHPNEDKFRRLRKSNPAFQRRVARFPGAVELLLAAGFAEEGVS----GPDT 76
                        90       100
                ....*....|....*....|.
gi 22327362 577 YLVLkRNDPGLLWIAKSMIEE 597
Cdd:cd10463  77 YLLL-RNDPGLLWLAKSSVEE 96
PUB cd09212
PNGase/UBA or UBX (PUB) domain of p97 adaptor proteins; The PUB domain is found in p97 adaptor ...
498-597 3.38e-21

PNGase/UBA or UBX (PUB) domain of p97 adaptor proteins; The PUB domain is found in p97 adaptor proteins such as PNGase, UBXD1 (UBX domain-containing protein 1), and RNF31 (RING finger protein 31). It functions as a p97 (also known as valosin-containing protein or VCP) adaptor by interacting with the D1 and/or D2 ATPase domains. The p97, a type II AAA+ ATPase, is involved in a variety of cellular processes such as the deglycosylation of ERAD substrates, membrane fusion, transcription factor activation and cell cycle regulation through differential binding to specific adaptor proteins. The PUB domain in UBX-domain protein 1 (UBXD1), which is widely expressed in higher eukaryotes (except for fungi) and which is involved in substrate recruitment to p97, interacts strongly with the C-terminus of p97. Peptide:N-glycanase (PNGase), a deglycosylating enzyme that functions in proteasome-dependent degradation of misfolded glycoproteins which are translocated from the endoplasmic reticulum (ER) to the cytosol during ERAD, associates with the ubiquitin-proteasome system proteins mediated by the N-terminal PUB domain. PNGase is present in all eukaryotic organisms; however, the yeast PNGase ortholog does not contain the PUB domain. The RNF31 protein, also known as HOIP or Zibra, contains an N-terminal PUB domain similar to those in PNGase and UBXD1, suggesting its association with p97.


Pssm-ID: 198416  Cd Length: 96  Bit Score: 88.59  E-value: 3.38e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22327362 498 IKALRNEVSPGQATTVLQMLLKIVRNIIEQPNEMKFKRLRKGNPAIKRNILNFPAAVEILSVVGFVdemvsESTGAQEPY 577
Cdd:cd09212   1 LDALRSNNDLEAFKEALKTLLKILDNILSNPTEEKYRRIRLSNKAFQEKVLPVPGGLELLLALGFV-----EETESGESF 75
                        90       100
                ....*....|....*....|.
gi 22327362 578 LVLK-RNDPGLLWIAKSMIEE 597
Cdd:cd09212  76 LVLPdDADVDLLKDAKAALEE 96
PUB pfam09409
PUB domain; The PUB (also known as PUG) domain is found in peptide N-glycanase where it ...
509-593 2.21e-15

PUB domain; The PUB (also known as PUG) domain is found in peptide N-glycanase where it functions as a AAA ATPase binding domain. This domain is also found on other proteins linked to the ubiquitin-proteasome system.


Pssm-ID: 462790  Cd Length: 80  Bit Score: 71.15  E-value: 2.21e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22327362   509 QATTVLQMLLKIVRNIIEQPNEMKFKRLRKGNPAIKRNILNFPAAVEILSVVGFVDEmvsestgAQEPYLVLKRNDPGLL 588
Cdd:pfam09409   3 KVKEALETLLKYLNNILSNPNEEKYRKIRLSNKAFQEKVLPLEGALELLLAIGFEKE-------DEEEFLLLEEESLKQL 75

                  ....*
gi 22327362   589 WIAKS 593
Cdd:pfam09409  76 AVLLE 80
PUG smart00580
domain in protein kinases, N-glycanases and other nuclear proteins;
513-581 7.74e-12

domain in protein kinases, N-glycanases and other nuclear proteins;


Pssm-ID: 197798  Cd Length: 57  Bit Score: 60.39  E-value: 7.74e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 22327362    513 VLQMLLKIVRNIIEQPNEMKfkrlrkGNPAIKRNILNFPAAVEILSVVGFVDEMVSestgaqEPYLVLK 581
Cdd:smart00580   1 SVRDLLRALRNILHHPREEK------GNPAIKERLGPVPGGFELYFTVGFPRLLIS------EVYTLPK 57
PUB_UBA_plant cd10461
PNGase/UBA or UBX (PUB) domain of plant Ubiquitin-associated (UBA) domain containing proteins; ...
494-584 1.13e-10

PNGase/UBA or UBX (PUB) domain of plant Ubiquitin-associated (UBA) domain containing proteins; The PUB domain functions as a p97 (also known as valosin-containing protein or VCP) adaptor by interacting with the D1 and/or D2 ATPase domains. The type II AAA+ ATPase p97 is involved in a variety of cellular processes such as the deglycosylation of ERAD substrates, membrane fusion, transcription factor activation and cell cycle regulation through differential binding to specific adaptor proteins. The UBA domain, along with UBL (ubiquitin-like) domain, has been implicated in proteasomal degradation by associating with substrates destined for degradation as well as with subunits of the proteasome, thus regulating protein turnover. This family contains only plant UBA domain-containing proteins.


Pssm-ID: 198419  Cd Length: 107  Bit Score: 58.98  E-value: 1.13e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22327362 494 LKKAIKAlrnevSPGQATTVLQMLLKIVRNIIEQPNEMKFKRLRKGNPAIKRNILNFPAAVEILSVVGFVDEMVSEstga 573
Cdd:cd10461   4 LKKAHKD-----DPDAVKTAFQTLLTYLGNVAKNPDEEKFRRIRLTNAAFQERVGALRGGIEFLELCGFERDEGDE---- 74
                        90
                ....*....|.
gi 22327362 574 qepYLVLKRND 584
Cdd:cd10461  75 ---ALVLPRDK 82
PUB_UBA cd10462
PNGase/UBA or UBX (PUB) domain of Ubiquitin-associated (UBA) domain containing proteins; The ...
492-564 6.32e-07

PNGase/UBA or UBX (PUB) domain of Ubiquitin-associated (UBA) domain containing proteins; The PUB domain functions as a p97 (also known as valosin-containing protein or VCP) adaptor by interacting with the D1 and/or D2 ATPase domains. The type II AAA+ ATPase p97 is involved in a variety of cellular processes such as the deglycosylation of ERAD substrates, membrane fusion, transcription factor activation and cell cycle regulation through differential binding to specific adaptor proteins. The UBA domain, along with UBL (ubiquitin-like) domain, has been implicated in proteasomal degradation by associating with substrates destined for degradation as well as with subunits of the proteasome, thus regulating protein turnover.


Pssm-ID: 198420  Cd Length: 100  Bit Score: 47.87  E-value: 6.32e-07
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 22327362 492 NRLKKAIKALRNEvspgQATTVLQMLLKIVRNIIEQPNEMKFKRLRKGNPAIKRNILNFPAAVEILSVVGFVD 564
Cdd:cd10462   2 NNLKKEYKDTDKQ----GLMTCLNTLRTYISNAHDHPLEEKYKKIRKENKAFVSKVLIFEGAIEILLACGFED 70
PUB_PNGase cd10459
PNGase/UBA or UBX (PUB) domain of the P97 adaptor protein Peptide:N-glycanase (PNGase); This ...
515-565 1.05e-06

PNGase/UBA or UBX (PUB) domain of the P97 adaptor protein Peptide:N-glycanase (PNGase); This PUB (PNGase/UBA or UBX) domain is found in the p97 adaptor protein PNGase (Peptide:N-glycanase). The PUB domain functions as a p97 (also known as valosin-containing protein or VCP) adaptor by interacting with the D1 and/or D2 ATPase domains. The type II AAA+ ATPase p97 is involved in a variety of cellular processes such as the deglycosylation of ERAD substrates, membrane fusion, transcription factor activation and cell cycle regulation through differential binding to specific adaptor proteins. Peptide:N-glycanase (PNGase), a deglycosylating enzyme that functions in proteasome-dependent degradation of misfolded glycoproteins which are translocated from the endoplasmic reticulum (ER) to the cytosol during ERAD, associates with the ubiquitin-proteasome system proteins mediated by the N-terminal PUB domain. PNGase is present in all eukaryotic organisms; however, the yeast PNGase ortholog does not contain the PUB domain. The mammalian PNGase binds a considerable number of proteins via its PUB domain; these include ERAD E3 enzyme, the autocrine motility factor receptor (AMFR or gp78), SAKS and Derlin-1.


Pssm-ID: 198417  Cd Length: 93  Bit Score: 46.88  E-value: 1.05e-06
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|.
gi 22327362 515 QMLLKIVRNIIEQPNEMKFKRLRKGNPAIKRNILNFPAAVEILSVVGFVDE 565
Cdd:cd10459  17 EALLTYANNILRNPNDPKYRSIRLDNPVFSTKLLPARGAIECLFEMGFVED 67
PUB_UBXD1 cd10460
PNGase/UBA or UBX (PUB) domain of UBXD1; This PUB domain is found in p97 adaptor protein ...
517-582 3.34e-06

PNGase/UBA or UBX (PUB) domain of UBXD1; This PUB domain is found in p97 adaptor protein UBXD1 (UBX domain-containing protein 1, also called UBXD6). It functions as a p97 (also known as valosin-containing protein or VCP) adaptor by interacting with the D1 and/or D2 ATPase domains. The type II AAA+ ATPase p97 is involved in a variety of cellular processes such as the deglycosylation of ERAD substrates, membrane fusion, transcription factor activation and cell cycle regulation through differential binding to specific adaptor proteins. The PUB domain in UBX-domain protein 1 (UBXD1), which is widely expressed in higher eukaryotes, except for fungi, and which is involved in substrate recruitment to p97, interacts strongly with the C-terminus of p97. UBXD1 also interacts with HRD1 and HERP, both components of the ERAD pathway, via p97. It is possibly involved in aggresome formation; aggresomes are perinuclear compartments that contain misfolded proteins colocalized with centrosome markers.


Pssm-ID: 198418  Cd Length: 102  Bit Score: 45.70  E-value: 3.34e-06
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 22327362 517 LLKIVRNIIEQPNEMKFKRLRKGNPAIKRNILNFPAAVEILSVVGFVDEMVSEStGAQEPYLVLKR 582
Cdd:cd10460  21 LCKYLENIIDHPDEEKYRKIRLSNKVFQEKVLPVEGALEFLEAAGFEEKTLPEQ-EDEEDFLVLSE 85
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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