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Conserved domains on  [gi|15242801|ref|NP_198317|]
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Glucose-6-phosphate/phosphate translocator-like protein [Arabidopsis thaliana]

Protein Classification

triose-phosphate transporter family protein( domain architecture ID 12042449)

triose-phosphate transporter family protein such as Arabidopsis thaliana chloroplastic phosphoenolpyruvate/phosphate translocators which transport phosphoenolpyruvate, 2-phosphoglycerate, 3-phosphoglycerate and/or dihydroxyacetone phosphate

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
TPT pfam03151
Triose-phosphate Transporter family; This family includes transporters with a specificity for ...
106-396 5.11e-139

Triose-phosphate Transporter family; This family includes transporters with a specificity for triose phosphate.


:

Pssm-ID: 308657 [Multi-domain]  Cd Length: 290  Bit Score: 398.59  E-value: 5.11e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801   106 LELGLLFAMWYLFNIYFNIYNKQVLKALHAPMTVTLVQFAVGSVLITIMWVLNLYKRPKISGAQLAAILPLAVVHTLGNL 185
Cdd:pfam03151   1 LKLGLLFGLWYFLNIYFNIYNKKILNAFPYPMTVSSVQLFVGSVYILVLWGTGLRKRPKISSPFLKNILPLALCHTLGHV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801   186 FTNMSLGKVSVSFTHTIKAMEPFFSVLLSAMFLGEKPTPWVLGAIVPIVGGVALASISEVSFNWAGFSSAMASNLTNQSR 265
Cdd:pfam03151  81 LANVSLGKVAVSFTHTVKAMEPFFTVILSRLFLGEYPPLLVYLSLLPIVGGVALASVTELSFNWIGFISAMISNLGFSLR 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801   266 NVLSKKVMVKKdDSLDNITLFSIITLMSLVLMAPVTFFTEGIKFTPSYIQSAGVNVKQIYTKSLIAALCFHAYQQVSYMI 345
Cdd:pfam03151 161 NIFSKKLMKGK-DNLDNLNLFAIITILSLLLLLPVWLLVEGFKKFPSLLQSGKVGLKDVYMLLLLSGVCFHLYNQVAYMI 239
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 15242801   346 LARVSPVTHSVGNCVKRVVVIVSSVIFFKTPVSPVNAFGTGIALAGVFLYS 396
Cdd:pfam03151 240 LERVSPVTHSVANTVKRVVVIVSSILVFGNPVSPLNAIGTAIAIAGVFLYS 290
 
Name Accession Description Interval E-value
TPT pfam03151
Triose-phosphate Transporter family; This family includes transporters with a specificity for ...
106-396 5.11e-139

Triose-phosphate Transporter family; This family includes transporters with a specificity for triose phosphate.


Pssm-ID: 308657 [Multi-domain]  Cd Length: 290  Bit Score: 398.59  E-value: 5.11e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801   106 LELGLLFAMWYLFNIYFNIYNKQVLKALHAPMTVTLVQFAVGSVLITIMWVLNLYKRPKISGAQLAAILPLAVVHTLGNL 185
Cdd:pfam03151   1 LKLGLLFGLWYFLNIYFNIYNKKILNAFPYPMTVSSVQLFVGSVYILVLWGTGLRKRPKISSPFLKNILPLALCHTLGHV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801   186 FTNMSLGKVSVSFTHTIKAMEPFFSVLLSAMFLGEKPTPWVLGAIVPIVGGVALASISEVSFNWAGFSSAMASNLTNQSR 265
Cdd:pfam03151  81 LANVSLGKVAVSFTHTVKAMEPFFTVILSRLFLGEYPPLLVYLSLLPIVGGVALASVTELSFNWIGFISAMISNLGFSLR 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801   266 NVLSKKVMVKKdDSLDNITLFSIITLMSLVLMAPVTFFTEGIKFTPSYIQSAGVNVKQIYTKSLIAALCFHAYQQVSYMI 345
Cdd:pfam03151 161 NIFSKKLMKGK-DNLDNLNLFAIITILSLLLLLPVWLLVEGFKKFPSLLQSGKVGLKDVYMLLLLSGVCFHLYNQVAYMI 239
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 15242801   346 LARVSPVTHSVGNCVKRVVVIVSSVIFFKTPVSPVNAFGTGIALAGVFLYS 396
Cdd:pfam03151 240 LERVSPVTHSVANTVKRVVVIVSSILVFGNPVSPLNAIGTAIAIAGVFLYS 290
tpt TIGR00817
Tpt phosphate/phosphoenolpyruvate translocator; The 6-8 TMS Triose-phosphate Transporter (TPT) ...
106-406 3.90e-127

Tpt phosphate/phosphoenolpyruvate translocator; The 6-8 TMS Triose-phosphate Transporter (TPT) Family (TC 2.A.7.9)Functionally characterized members of the TPT family are derived from the inner envelope membranes of chloroplasts and nongreen plastids of plants. However,homologues are also present in yeast. Saccharomyces cerevisiae has three functionally uncharacterized TPT paralogues encoded within its genome. Under normal physiologicalconditions, chloroplast TPTs mediate a strict antiport of substrates, frequently exchanging an organic three carbon compound phosphate ester for inorganic phosphate (Pi).Normally, a triose-phosphate, 3-phosphoglycerate, or another phosphorylated C3 compound made in the chloroplast during photosynthesis, exits the organelle into thecytoplasm of the plant cell in exchange for Pi. However, experiments with reconstituted translocator in artificial membranes indicate that transport can also occur by achannel-like uniport mechanism with up to 10-fold higher transport rates. Channel opening may be induced by a membrane potential of large magnitude and/or by high substrateconcentrations. Nongreen plastid and chloroplast carriers, such as those from maize endosperm and root membranes, mediate transport of C3 compounds phosphorylated atcarbon atom 2, particularly phosphenolpyruvate, in exchange for Pi. These are the phosphoenolpyruvate:Pi antiporters (PPT). Glucose-6-P has also been shown to be asubstrate of some plastid translocators (GPT). The three types of proteins (TPT, PPT and GPT) are divergent in sequence as well as substrate specificity, but their substratespecificities overlap. [Hypothetical proteins, Conserved]


Pssm-ID: 129898 [Multi-domain]  Cd Length: 302  Bit Score: 368.67  E-value: 3.90e-127
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801   106 LELGLLFAMWYLFNIYFNIYNKQVLKALHAPMTVTLVQFAVGSVLITIMWVLNLYKRPKISGAQLAAILPLAVVHTLGNL 185
Cdd:TIGR00817   1 LQTGLLFGLWYFLNVYFNIYNKKLLNVFPYPYFKTLISLAVGSLYCLLSWSSGLPKRLKISSALLKLLLPVAIVHTIGHV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801   186 FTNMSLGKVSVSFTHTIKAMEPFFSVLLSAMFLGEKPTPWVLGAIVPIVGGVALASISEVSFNWAGFSSAMASNLTNQSR 265
Cdd:TIGR00817  81 TSNVSLSKVAVSFTHTIKAMEPFFSVVLSAFFLGQEFPSTLWLSLLPIVGGVALASDTELSFNWAGFLSAMISNITFVSR 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801   266 NVLSKKVMVKKddSLDNITLFSIITLMSLVLMAPVTFFTEGIKFTPSYIQSA--GVNVKQIYTKSLIAAL-CFHAYQQVS 342
Cdd:TIGR00817 161 NIFSKKAMTIK--SLDKTNLYAYISIMSLFLLSPPAFITEGPPFLPHGFMQAisGVNVTKIYTVSLVAAMgFFHFYQQVA 238
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15242801   343 YMILARVSPVTHSVGNCVKRVVVIVSSVIFFKTPVSPVNAFGTGIALAGVFLYSRVKGIKPKPK 406
Cdd:TIGR00817 239 FMLLGRVSPLTHSVGNCMKRVVVIVVSILFFGTKISPQQVFGTGIAIAGVFLYSRVKAQKPKPK 302
PTZ00343 PTZ00343
triose or hexose phosphate/phosphate translocator; Provisional
106-399 4.76e-62

triose or hexose phosphate/phosphate translocator; Provisional


Pssm-ID: 240371 [Multi-domain]  Cd Length: 350  Bit Score: 203.81  E-value: 4.76e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801  106 LELGLLFAMWYLFNIYFNIYNKQVLKALHAPMTVTLVQFAVGSVLITIMWVLNLYKRPKISGAQLA--AILPLAVVHTLG 183
Cdd:PTZ00343  48 WKLALLFLTWYALNVLYVVDNKLALNMLPLPWTISSLQLFVGWLFALLYWATGFRKIPRIKSLKLFlkNFLPQGLCHLFV 127
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801  184 NLFTNMSLGKVSVSFTHTIKAMEPFFSVLLSAMFLGEKPTPWVLGAIVPIVGGVALASISEVSFNWAGFSSAMASNLTNQ 263
Cdd:PTZ00343 128 HFGAVISMGLGAVSFTHVVKAAEPVFTALLSILFLKQFLNLYAYLSLIPIVGGVALASVKELHFTWLAFWCAMLSNLGSS 207
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801  264 SRNVLSKKVMVKKDDSLDNIT---LFSIITLMSLVLMAPVTFFTEGIKFTPSYIQSAGV----NVKQIYTKSLIAALCFH 336
Cdd:PTZ00343 208 LRSIFAKKTMKNKSEIGENLTasnIYMLLTLIASLISLPLVLFFEGKKWVPVWTNYTANmtnyTKGIIIFKIFFSGVWYY 287
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15242801  337 AYQQVSYMILARVSPVTHSVGNCVKRVVVIVSSVIFFKTPVSPVNAFGTGIALAGVFLYSRVK 399
Cdd:PTZ00343 288 LYNEVAFYCLGKVNQVTHAVANTLKRVVIIVSSIIIFQTQVTLLGYLGMAVAILGALLYSLFK 350
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
122-244 8.07e-12

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 65.25  E-value: 8.07e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801 122 FNIYNKQVLKALHaPMTVTLVQFAVGSVLITIMWVLNLYKRPkISGAQLAAILPLAVVHT-LGNLFTNMSLGKVSVSFTH 200
Cdd:COG0697 164 YTVLTRRLSRRLD-PLTLTFWQMLVGALLLLPLALLTGLPLP-LSAAAWLALLYLGLFGTaLAYLLWFRALRRLGASRAA 241
                        90       100       110       120
                ....*....|....*....|....*....|....*....|....
gi 15242801 201 TIKAMEPFFSVLLSAMFLGEKPTPWVLGAIVPIVGGVALASISE 244
Cdd:COG0697 242 PLTYLEPVFAVLLGWLLLGEPLTPLQLLGAALILAGVLLAALRE 285
TPT_S35C2 cd21092
solute carrier family 35 member C2, member of the triose-phosphate transporter family; Solute ...
173-404 8.88e-07

solute carrier family 35 member C2, member of the triose-phosphate transporter family; Solute carrier family 35 member C2 (S35C2 or Slc35c2), also called ovarian cancer-overexpressed gene 1 protein (OVCOV1), is a member of the triose-phosphate transporter (TPT) family, which is part of the drug/metabolite transporter (DMT) superfamily. It may function either as a GDP-fucose transporter that competes with Slc35c1 (S35C1) for GDP-fucose, or a factor that otherwise enhances the fucosylation of Notch and is required for optimal Notch signaling in mammalian cells.


Pssm-ID: 411044  Cd Length: 248  Bit Score: 49.96  E-value: 8.88e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801 173 ILPLAVVHTLGNLFTNMSLGKVSVSFTHTIKAMEPFFSVLLSAMFLGEKPTPWVLGAIVPIVGGVALASISEVSFNWAGF 252
Cdd:cd21092   8 VAPTGLASALDIGLSNWSFLFITVSLYTMTKSSAIIFILFFSLVFKLEKPRWSLVLVVLLIAGGLFMFTYKSTQFNLEGF 87
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801 253 SSAMASNLTNQSRNVLSKKVMVKKDDSLDNI--TLFSIITLMSLVLMaPVTFFTEGIKFTPS----YIQSAGVNVKQIYT 326
Cdd:cd21092  88 ILVLSASFLGGLRWTLAQLLMQKAELGLQNPidMMYHLQPWMILGLL-PLAIGFEGLHLATSeklfRFHDSSVLLRTLGY 166
                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15242801 327 KSLIAALCFhaYQQVS-YMILARVSPVTHSVGNCVKRVVVIVSSVIFFKTPVSPVNAFGTGIALAGVFLYSRVKGIKPK 404
Cdd:cd21092 167 LLLGAVLAF--GLEFSeFLLVSKTSSLTLSIAGIFKEICTLLLAVHINGDHLSLLNWLGLVICLCGISLHVVLKALHSK 243
 
Name Accession Description Interval E-value
TPT pfam03151
Triose-phosphate Transporter family; This family includes transporters with a specificity for ...
106-396 5.11e-139

Triose-phosphate Transporter family; This family includes transporters with a specificity for triose phosphate.


Pssm-ID: 308657 [Multi-domain]  Cd Length: 290  Bit Score: 398.59  E-value: 5.11e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801   106 LELGLLFAMWYLFNIYFNIYNKQVLKALHAPMTVTLVQFAVGSVLITIMWVLNLYKRPKISGAQLAAILPLAVVHTLGNL 185
Cdd:pfam03151   1 LKLGLLFGLWYFLNIYFNIYNKKILNAFPYPMTVSSVQLFVGSVYILVLWGTGLRKRPKISSPFLKNILPLALCHTLGHV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801   186 FTNMSLGKVSVSFTHTIKAMEPFFSVLLSAMFLGEKPTPWVLGAIVPIVGGVALASISEVSFNWAGFSSAMASNLTNQSR 265
Cdd:pfam03151  81 LANVSLGKVAVSFTHTVKAMEPFFTVILSRLFLGEYPPLLVYLSLLPIVGGVALASVTELSFNWIGFISAMISNLGFSLR 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801   266 NVLSKKVMVKKdDSLDNITLFSIITLMSLVLMAPVTFFTEGIKFTPSYIQSAGVNVKQIYTKSLIAALCFHAYQQVSYMI 345
Cdd:pfam03151 161 NIFSKKLMKGK-DNLDNLNLFAIITILSLLLLLPVWLLVEGFKKFPSLLQSGKVGLKDVYMLLLLSGVCFHLYNQVAYMI 239
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 15242801   346 LARVSPVTHSVGNCVKRVVVIVSSVIFFKTPVSPVNAFGTGIALAGVFLYS 396
Cdd:pfam03151 240 LERVSPVTHSVANTVKRVVVIVSSILVFGNPVSPLNAIGTAIAIAGVFLYS 290
tpt TIGR00817
Tpt phosphate/phosphoenolpyruvate translocator; The 6-8 TMS Triose-phosphate Transporter (TPT) ...
106-406 3.90e-127

Tpt phosphate/phosphoenolpyruvate translocator; The 6-8 TMS Triose-phosphate Transporter (TPT) Family (TC 2.A.7.9)Functionally characterized members of the TPT family are derived from the inner envelope membranes of chloroplasts and nongreen plastids of plants. However,homologues are also present in yeast. Saccharomyces cerevisiae has three functionally uncharacterized TPT paralogues encoded within its genome. Under normal physiologicalconditions, chloroplast TPTs mediate a strict antiport of substrates, frequently exchanging an organic three carbon compound phosphate ester for inorganic phosphate (Pi).Normally, a triose-phosphate, 3-phosphoglycerate, or another phosphorylated C3 compound made in the chloroplast during photosynthesis, exits the organelle into thecytoplasm of the plant cell in exchange for Pi. However, experiments with reconstituted translocator in artificial membranes indicate that transport can also occur by achannel-like uniport mechanism with up to 10-fold higher transport rates. Channel opening may be induced by a membrane potential of large magnitude and/or by high substrateconcentrations. Nongreen plastid and chloroplast carriers, such as those from maize endosperm and root membranes, mediate transport of C3 compounds phosphorylated atcarbon atom 2, particularly phosphenolpyruvate, in exchange for Pi. These are the phosphoenolpyruvate:Pi antiporters (PPT). Glucose-6-P has also been shown to be asubstrate of some plastid translocators (GPT). The three types of proteins (TPT, PPT and GPT) are divergent in sequence as well as substrate specificity, but their substratespecificities overlap. [Hypothetical proteins, Conserved]


Pssm-ID: 129898 [Multi-domain]  Cd Length: 302  Bit Score: 368.67  E-value: 3.90e-127
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801   106 LELGLLFAMWYLFNIYFNIYNKQVLKALHAPMTVTLVQFAVGSVLITIMWVLNLYKRPKISGAQLAAILPLAVVHTLGNL 185
Cdd:TIGR00817   1 LQTGLLFGLWYFLNVYFNIYNKKLLNVFPYPYFKTLISLAVGSLYCLLSWSSGLPKRLKISSALLKLLLPVAIVHTIGHV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801   186 FTNMSLGKVSVSFTHTIKAMEPFFSVLLSAMFLGEKPTPWVLGAIVPIVGGVALASISEVSFNWAGFSSAMASNLTNQSR 265
Cdd:TIGR00817  81 TSNVSLSKVAVSFTHTIKAMEPFFSVVLSAFFLGQEFPSTLWLSLLPIVGGVALASDTELSFNWAGFLSAMISNITFVSR 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801   266 NVLSKKVMVKKddSLDNITLFSIITLMSLVLMAPVTFFTEGIKFTPSYIQSA--GVNVKQIYTKSLIAAL-CFHAYQQVS 342
Cdd:TIGR00817 161 NIFSKKAMTIK--SLDKTNLYAYISIMSLFLLSPPAFITEGPPFLPHGFMQAisGVNVTKIYTVSLVAAMgFFHFYQQVA 238
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15242801   343 YMILARVSPVTHSVGNCVKRVVVIVSSVIFFKTPVSPVNAFGTGIALAGVFLYSRVKGIKPKPK 406
Cdd:TIGR00817 239 FMLLGRVSPLTHSVGNCMKRVVVIVVSILFFGTKISPQQVFGTGIAIAGVFLYSRVKAQKPKPK 302
PTZ00343 PTZ00343
triose or hexose phosphate/phosphate translocator; Provisional
106-399 4.76e-62

triose or hexose phosphate/phosphate translocator; Provisional


Pssm-ID: 240371 [Multi-domain]  Cd Length: 350  Bit Score: 203.81  E-value: 4.76e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801  106 LELGLLFAMWYLFNIYFNIYNKQVLKALHAPMTVTLVQFAVGSVLITIMWVLNLYKRPKISGAQLA--AILPLAVVHTLG 183
Cdd:PTZ00343  48 WKLALLFLTWYALNVLYVVDNKLALNMLPLPWTISSLQLFVGWLFALLYWATGFRKIPRIKSLKLFlkNFLPQGLCHLFV 127
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801  184 NLFTNMSLGKVSVSFTHTIKAMEPFFSVLLSAMFLGEKPTPWVLGAIVPIVGGVALASISEVSFNWAGFSSAMASNLTNQ 263
Cdd:PTZ00343 128 HFGAVISMGLGAVSFTHVVKAAEPVFTALLSILFLKQFLNLYAYLSLIPIVGGVALASVKELHFTWLAFWCAMLSNLGSS 207
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801  264 SRNVLSKKVMVKKDDSLDNIT---LFSIITLMSLVLMAPVTFFTEGIKFTPSYIQSAGV----NVKQIYTKSLIAALCFH 336
Cdd:PTZ00343 208 LRSIFAKKTMKNKSEIGENLTasnIYMLLTLIASLISLPLVLFFEGKKWVPVWTNYTANmtnyTKGIIIFKIFFSGVWYY 287
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15242801  337 AYQQVSYMILARVSPVTHSVGNCVKRVVVIVSSVIFFKTPVSPVNAFGTGIALAGVFLYSRVK 399
Cdd:PTZ00343 288 LYNEVAFYCLGKVNQVTHAVANTLKRVVIIVSSIIIFQTQVTLLGYLGMAVAILGALLYSLFK 350
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
122-244 8.07e-12

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 65.25  E-value: 8.07e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801 122 FNIYNKQVLKALHaPMTVTLVQFAVGSVLITIMWVLNLYKRPkISGAQLAAILPLAVVHT-LGNLFTNMSLGKVSVSFTH 200
Cdd:COG0697 164 YTVLTRRLSRRLD-PLTLTFWQMLVGALLLLPLALLTGLPLP-LSAAAWLALLYLGLFGTaLAYLLWFRALRRLGASRAA 241
                        90       100       110       120
                ....*....|....*....|....*....|....*....|....
gi 15242801 201 TIKAMEPFFSVLLSAMFLGEKPTPWVLGAIVPIVGGVALASISE 244
Cdd:COG0697 242 PLTYLEPVFAVLLGWLLLGEPLTPLQLLGAALILAGVLLAALRE 285
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
136-306 1.77e-11

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 64.48  E-value: 1.77e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801 136 PMTVTLVQFAVGSVLITIMWVLNLYKRPKISGAQLAAILPLAVV-HTLGNLFTNMSLGKVSVSFTHTIKAMEPFFSVLLS 214
Cdd:COG0697  31 PLQLAFLRFLLAALLLLPLLLLRGRRLPPLSRRDWLLLLLRGLLgLALAFLLFFLALQYTPAALAALLLALAPLFVALLA 110
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801 215 AMFLGEKPTPWVLGAIVPIVGGVALAS---ISEVSFNWAGFSSAMASNLTNQSRNVLSKKVMVKkddsLDNITLFSIITL 291
Cdd:COG0697 111 ALLLGERLSRRRWLGLLLGFAGVLLIVgpgGGGGGGSLLGDLLALLAALSWALYTVLTRRLSRR----LDPLTLTFWQML 186
                       170
                ....*....|....*
gi 15242801 292 MSLVLMAPVTFFTEG 306
Cdd:COG0697 187 VGALLLLPLALLTGL 201
EamA pfam00892
EamA-like transporter family; This family includes many hypothetical membrane proteins of ...
124-242 2.37e-09

EamA-like transporter family; This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.


Pssm-ID: 307170  Cd Length: 136  Bit Score: 55.28  E-value: 2.37e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801   124 IYNKQVLKALHaPMTVTLVQFAVGSvLITIMWVLNLYKRPKISGAQLAAILPLAVVHT-LGNLFTNMSLGKVSVSFTHTI 202
Cdd:pfam00892  19 VFSKILLRRIS-PLTLTFWRFLIAG-ILLLPFALFTGGKLVIPLKSWLALLYLGVLGTfLGFLLYFYGLKYVSASNASVI 96
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 15242801   203 KAMEPFFSVLLSAMFLGEKPTPWVLGAIVPIVGGVALASI 242
Cdd:pfam00892  97 TSLSPVFTLILSVLLLGEKLTLKQLLGIVLILLGVLLILL 136
RibN COG2510
Riboflavin transporter RibN, EamA domain [Coenzyme transport and metabolism];
123-243 1.37e-07

Riboflavin transporter RibN, EamA domain [Coenzyme transport and metabolism];


Pssm-ID: 442000  Cd Length: 138  Bit Score: 50.18  E-value: 1.37e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801 123 NIYNKQVLKALHaPMTVTLVQFAVGSVLITIMWVLN--LYKRPKISGAQLAAILPLAVVHTLGNLFTNMSLGKVSVSFTH 200
Cdd:COG2510  17 AIFAKIGLKGID-PNLATFIRTLVALIFLLLILLVTgkLGELPELSPKSWLFLLLSGLATGLSWLFYFRALKLGPASIVA 95
                        90       100       110       120
                ....*....|....*....|....*....|....*....|...
gi 15242801 201 TIKAMEPFFSVLLSAMFLGEKPTPWVLGAIVPIVGGVALASIS 243
Cdd:COG2510  96 PIDKLSPVFTVLLSVLFLGERLTLKQIIGILLIVAGVILLSLK 138
TPT_S35C2 cd21092
solute carrier family 35 member C2, member of the triose-phosphate transporter family; Solute ...
173-404 8.88e-07

solute carrier family 35 member C2, member of the triose-phosphate transporter family; Solute carrier family 35 member C2 (S35C2 or Slc35c2), also called ovarian cancer-overexpressed gene 1 protein (OVCOV1), is a member of the triose-phosphate transporter (TPT) family, which is part of the drug/metabolite transporter (DMT) superfamily. It may function either as a GDP-fucose transporter that competes with Slc35c1 (S35C1) for GDP-fucose, or a factor that otherwise enhances the fucosylation of Notch and is required for optimal Notch signaling in mammalian cells.


Pssm-ID: 411044  Cd Length: 248  Bit Score: 49.96  E-value: 8.88e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801 173 ILPLAVVHTLGNLFTNMSLGKVSVSFTHTIKAMEPFFSVLLSAMFLGEKPTPWVLGAIVPIVGGVALASISEVSFNWAGF 252
Cdd:cd21092   8 VAPTGLASALDIGLSNWSFLFITVSLYTMTKSSAIIFILFFSLVFKLEKPRWSLVLVVLLIAGGLFMFTYKSTQFNLEGF 87
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801 253 SSAMASNLTNQSRNVLSKKVMVKKDDSLDNI--TLFSIITLMSLVLMaPVTFFTEGIKFTPS----YIQSAGVNVKQIYT 326
Cdd:cd21092  88 ILVLSASFLGGLRWTLAQLLMQKAELGLQNPidMMYHLQPWMILGLL-PLAIGFEGLHLATSeklfRFHDSSVLLRTLGY 166
                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15242801 327 KSLIAALCFhaYQQVS-YMILARVSPVTHSVGNCVKRVVVIVSSVIFFKTPVSPVNAFGTGIALAGVFLYSRVKGIKPK 404
Cdd:cd21092 167 LLLGAVLAF--GLEFSeFLLVSKTSSLTLSIAGIFKEICTLLLAVHINGDHLSLLNWLGLVICLCGISLHVVLKALHSK 243
RhtA COG5006
Threonine/homoserine efflux transporter RhtA [Amino acid transport and metabolism];
108-244 1.44e-03

Threonine/homoserine efflux transporter RhtA [Amino acid transport and metabolism];


Pssm-ID: 444030 [Multi-domain]  Cd Length: 290  Bit Score: 40.19  E-value: 1.44e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242801 108 LGLLFA-----MWYLfniYFnIYNKQVLKALHAPMTVTLVqFAVGSVLIT---IMWVLNLYKRPKISGAQLA-AILPLAV 178
Cdd:COG5006 145 VGVLFAlgaaaCWAL---YI-LLGRRVGARLPGLTGLALG-MLVAALVLLpfgLPTAGPALLDPPVLLLGLGvAVLSSVL 219
                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15242801 179 VHTLGNlftnMSLGKVSVSFTHTIKAMEPFFSVLLSAMFLGEKPTPWVLGAIVPIVGGVALASISE 244
Cdd:COG5006 220 PYSLEM----VALRRLPARTFGILMSLEPAVAALAGWLVLGEVLTPLQWLGIALVVAASAGATLTA 281
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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