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Conserved domains on  [gi|15241875|ref|NP_198217|]
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WRKY DNA-binding protein 74 [Arabidopsis thaliana]

Protein Classification

WRKY transcription factor( domain architecture ID 10565326)

WRKY transcription factor is predominantly found in plants and is involved in multiple aspects of plant growth, development and stress response

CATH:  2.20.25.80
Gene Ontology:  GO:0003700
PubMed:  20304701
SCOP:  4003937

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
WRKY smart00774
DNA binding domain; The WRKY domain is a DNA binding domain found in one or two copies in a ...
 261-319 1.68e-34

DNA binding domain; The WRKY domain is a DNA binding domain found in one or two copies in a superfamily of plant transcription factors. These transcription factors are involved in the regulation of various physiological programs that are unique to plants, including pathogen defense, senescence and trichome development. The domain is a 60 amino acid region that is defined by the conserved amino acid sequence WRKYGQK at its N-terminal end, together with a novel zinc-finger-like motif. It binds specifically to the DNA sequence motif (T)(T)TGAC(C/T), which is known as the W box. The invariant TGAC core is essential for function and WRKY binding.


:

Pssm-ID: 214815  Cd Length: 59  Bit Score: 120.28  E-value: 1.68e-34
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 15241875    261 PPDEYSWRKYGQKPIKGSPHPRGYYKCSSVRGCPARKHVERCVEETSMLIVTYEGEHNH 319
Cdd:smart00774   1 LDDGYQWRKYGQKVIKGSPYPRSYYRCTYTQGCPAKKQVQRSDDDPSVVEVTYEGEHTH 59
Plant_zn_clust pfam10533
Plant zinc cluster domain; This zinc binding domain was identified by Babu and colleagues and ...
 221-259 1.10e-11

Plant zinc cluster domain; This zinc binding domain was identified by Babu and colleagues and found associated with the WRKY domain pfam03106.


:

Pssm-ID: 463137  Cd Length: 42  Bit Score: 58.89  E-value: 1.10e-11
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 15241875   221 SCSGSLKCGSKSKCHCSKKRKLRVKRSIKVPAISNKIAD 259
Cdd:pfam10533   4 SAGKNAKASSSGRCHCSKKRKSRVKRTIRVPAISSKAAD 42
 
Name Accession Description Interval E-value
WRKY smart00774
DNA binding domain; The WRKY domain is a DNA binding domain found in one or two copies in a ...
 261-319 1.68e-34

DNA binding domain; The WRKY domain is a DNA binding domain found in one or two copies in a superfamily of plant transcription factors. These transcription factors are involved in the regulation of various physiological programs that are unique to plants, including pathogen defense, senescence and trichome development. The domain is a 60 amino acid region that is defined by the conserved amino acid sequence WRKYGQK at its N-terminal end, together with a novel zinc-finger-like motif. It binds specifically to the DNA sequence motif (T)(T)TGAC(C/T), which is known as the W box. The invariant TGAC core is essential for function and WRKY binding.


Pssm-ID: 214815  Cd Length: 59  Bit Score: 120.28  E-value: 1.68e-34
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 15241875    261 PPDEYSWRKYGQKPIKGSPHPRGYYKCSSVRGCPARKHVERCVEETSMLIVTYEGEHNH 319
Cdd:smart00774   1 LDDGYQWRKYGQKVIKGSPYPRSYYRCTYTQGCPAKKQVQRSDDDPSVVEVTYEGEHTH 59
WRKY pfam03106
WRKY DNA -binding domain;
263-319 4.16e-33

WRKY DNA -binding domain;


Pssm-ID: 460808  Cd Length: 57  Bit Score: 116.81  E-value: 4.16e-33
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 15241875   263 DEYSWRKYGQKPIKGSPHPRGYYKCSSVRGCPARKHVERCVEETSMLIVTYEGEHNH 319
Cdd:pfam03106   1 DGYSWRKYGQKQIKGSKFPRSYYRCTHKPGCPAKKQVQRSPDDPSIFEVTYEGEHTH 57
Plant_zn_clust pfam10533
Plant zinc cluster domain; This zinc binding domain was identified by Babu and colleagues and ...
 221-259 1.10e-11

Plant zinc cluster domain; This zinc binding domain was identified by Babu and colleagues and found associated with the WRKY domain pfam03106.


Pssm-ID: 463137  Cd Length: 42  Bit Score: 58.89  E-value: 1.10e-11
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 15241875   221 SCSGSLKCGSKSKCHCSKKRKLRVKRSIKVPAISNKIAD 259
Cdd:pfam10533   4 SAGKNAKASSSGRCHCSKKRKSRVKRTIRVPAISSKAAD 42
 
Name Accession Description Interval E-value
WRKY smart00774
DNA binding domain; The WRKY domain is a DNA binding domain found in one or two copies in a ...
 261-319 1.68e-34

DNA binding domain; The WRKY domain is a DNA binding domain found in one or two copies in a superfamily of plant transcription factors. These transcription factors are involved in the regulation of various physiological programs that are unique to plants, including pathogen defense, senescence and trichome development. The domain is a 60 amino acid region that is defined by the conserved amino acid sequence WRKYGQK at its N-terminal end, together with a novel zinc-finger-like motif. It binds specifically to the DNA sequence motif (T)(T)TGAC(C/T), which is known as the W box. The invariant TGAC core is essential for function and WRKY binding.


Pssm-ID: 214815  Cd Length: 59  Bit Score: 120.28  E-value: 1.68e-34
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 15241875    261 PPDEYSWRKYGQKPIKGSPHPRGYYKCSSVRGCPARKHVERCVEETSMLIVTYEGEHNH 319
Cdd:smart00774   1 LDDGYQWRKYGQKVIKGSPYPRSYYRCTYTQGCPAKKQVQRSDDDPSVVEVTYEGEHTH 59
WRKY pfam03106
WRKY DNA -binding domain;
263-319 4.16e-33

WRKY DNA -binding domain;


Pssm-ID: 460808  Cd Length: 57  Bit Score: 116.81  E-value: 4.16e-33
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 15241875   263 DEYSWRKYGQKPIKGSPHPRGYYKCSSVRGCPARKHVERCVEETSMLIVTYEGEHNH 319
Cdd:pfam03106   1 DGYSWRKYGQKQIKGSKFPRSYYRCTHKPGCPAKKQVQRSPDDPSIFEVTYEGEHTH 57
Plant_zn_clust pfam10533
Plant zinc cluster domain; This zinc binding domain was identified by Babu and colleagues and ...
 221-259 1.10e-11

Plant zinc cluster domain; This zinc binding domain was identified by Babu and colleagues and found associated with the WRKY domain pfam03106.


Pssm-ID: 463137  Cd Length: 42  Bit Score: 58.89  E-value: 1.10e-11
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 15241875   221 SCSGSLKCGSKSKCHCSKKRKLRVKRSIKVPAISNKIAD 259
Cdd:pfam10533   4 SAGKNAKASSSGRCHCSKKRKSRVKRTIRVPAISSKAAD 42
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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