NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|15240432|ref|NP_198057|]
View 

AGAMOUS-like 101 [Arabidopsis thaliana]

Protein Classification

MADS-box domain-containing protein( domain architecture ID 10083688)

MADS (MCM1, AGAMOUS, DEFICIENS, and SRF, serum response factor)-box domain-containing protein functions as a transcription factor and may be involved in various important aspects of development and differentiation

CATH:  3.40.1810.10
Gene Ontology:  GO:0003700|GO:0046983
SCOP:  4001594

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
MADS_SRF_like cd00266
SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) ...
1-59 5.67e-16

SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero- and homo-dimers. Differs from the MEF-like/Type II subgroup mainly in position of the alpha 2 helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


:

Pssm-ID: 238166 [Multi-domain]  Cd Length: 83  Bit Score: 67.29  E-value: 5.67e-16
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 15240432   1 MFKKALELSTLCNIEVCVIYYGRDGELFKTWPEDEskVRDMAERFTKLNERERRKKRTN 59
Cdd:cd00266  27 LFKKASELSTLCGAEVAVIVYSPSGKLYVFWPSSE--VEGVISRFEVLSALERKKKAVD 83
 
Name Accession Description Interval E-value
MADS_SRF_like cd00266
SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) ...
1-59 5.67e-16

SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero- and homo-dimers. Differs from the MEF-like/Type II subgroup mainly in position of the alpha 2 helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


Pssm-ID: 238166 [Multi-domain]  Cd Length: 83  Bit Score: 67.29  E-value: 5.67e-16
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 15240432   1 MFKKALELSTLCNIEVCVIYYGRDGELFKTWPEDEskVRDMAERFTKLNERERRKKRTN 59
Cdd:cd00266  27 LFKKASELSTLCGAEVAVIVYSPSGKLYVFWPSSE--VEGVISRFEVLSALERKKKAVD 83
MADS smart00432
MADS domain;
1-32 7.97e-09

MADS domain;


Pssm-ID: 197721 [Multi-domain]  Cd Length: 59  Bit Score: 48.32  E-value: 7.97e-09
                           10        20        30
                   ....*....|....*....|....*....|..
gi 15240432      1 MFKKALELSTLCNIEVCVIYYGRDGELFKTWP 32
Cdd:smart00432  27 LFKKAHELSVLCDAEVALIVFSPTGKLYEFAS 58
SRF-TF pfam00319
SRF-type transcription factor (DNA-binding and dimerization domain);
1-28 2.36e-08

SRF-type transcription factor (DNA-binding and dimerization domain);


Pssm-ID: 459760 [Multi-domain]  Cd Length: 48  Bit Score: 46.65  E-value: 2.36e-08
                          10        20
                  ....*....|....*....|....*...
gi 15240432     1 MFKKALELSTLCNIEVCVIYYGRDGELF 28
Cdd:pfam00319  19 LFKKASELSVLCGAEVAVIVFSPTGKLY 46
 
Name Accession Description Interval E-value
MADS_SRF_like cd00266
SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) ...
1-59 5.67e-16

SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero- and homo-dimers. Differs from the MEF-like/Type II subgroup mainly in position of the alpha 2 helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


Pssm-ID: 238166 [Multi-domain]  Cd Length: 83  Bit Score: 67.29  E-value: 5.67e-16
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 15240432   1 MFKKALELSTLCNIEVCVIYYGRDGELFKTWPEDEskVRDMAERFTKLNERERRKKRTN 59
Cdd:cd00266  27 LFKKASELSTLCGAEVAVIVYSPSGKLYVFWPSSE--VEGVISRFEVLSALERKKKAVD 83
MADS cd00120
MADS: MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic ...
1-33 6.21e-11

MADS: MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptonal regulators. Binds DNA and exists as hetero and homo-dimers. Composed of 2 main subgroups: SRF-like/Type I and MEF2-like (myocyte enhancer factor 2)/ Type II. These subgroups differ mainly in position of the alpha 2 helix responsible for the dimerization interface; Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


Pssm-ID: 238067 [Multi-domain]  Cd Length: 59  Bit Score: 53.67  E-value: 6.21e-11
                        10        20        30
                ....*....|....*....|....*....|...
gi 15240432   1 MFKKALELSTLCNIEVCVIYYGRDGELFKTWPE 33
Cdd:cd00120  27 LFKKASELSVLCDAEVAVIVFSPSGKLYEFWSS 59
MADS smart00432
MADS domain;
1-32 7.97e-09

MADS domain;


Pssm-ID: 197721 [Multi-domain]  Cd Length: 59  Bit Score: 48.32  E-value: 7.97e-09
                           10        20        30
                   ....*....|....*....|....*....|..
gi 15240432      1 MFKKALELSTLCNIEVCVIYYGRDGELFKTWP 32
Cdd:smart00432  27 LFKKAHELSVLCDAEVALIVFSPTGKLYEFAS 58
SRF-TF pfam00319
SRF-type transcription factor (DNA-binding and dimerization domain);
1-28 2.36e-08

SRF-type transcription factor (DNA-binding and dimerization domain);


Pssm-ID: 459760 [Multi-domain]  Cd Length: 48  Bit Score: 46.65  E-value: 2.36e-08
                          10        20
                  ....*....|....*....|....*...
gi 15240432     1 MFKKALELSTLCNIEVCVIYYGRDGELF 28
Cdd:pfam00319  19 LFKKASELSVLCGAEVAVIVFSPTGKLY 46
MADS_MEF2_like cd00265
MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, ...
2-50 9.75e-03

MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I subgroup mainly in position of the alpha helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


Pssm-ID: 238165 [Multi-domain]  Cd Length: 77  Bit Score: 32.52  E-value: 9.75e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 15240432   2 FKKALELSTLCNIEVCVIYYGRDGELFktwpEDESK-VRDMAERFTKLNE 50
Cdd:cd00265  28 LKKAHELSVLCDAEVALIIFSSSGKLY----EFSSPsMEKIIERYQKTSG 73
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH
HHS Vulnerability Disclosure