NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|15237903|ref|NP_197804|]
View 

squalene monooxygenase 6 [Arabidopsis thaliana]

Protein Classification

NAD(P)-dependent oxidoreductase( domain architecture ID 11477344)

NAD(P)-dependent oxidoreductase catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PLN02985 PLN02985
squalene monooxygenase
 3-517 0e+00

squalene monooxygenase


:

Pssm-ID: 178566 [Multi-domain]  Cd Length: 514  Bit Score: 1065.67  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903    3 FTHVCLWTLVAFVLTWTVFYLTNMKKKATDLADTVAEDQKDGAADVIIVGAGVGGSALAYALAKDGRRVHVIERDMREPE 82
Cdd:PLN02985   1 FTHVCLWTLLAFVLTWTVFYVTNRKKKATELADAVAEERKDGATDVIIVGAGVGGSALAYALAKDGRRVHVIERDLREPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903   83 RMMGEFMQPGGRLMLSKLGLQDCLEDIDAQKATGLAVYKDGKEADAPFPVDNNNFSYEPSARSFHNGRFVQQLRRKAFSL 162
Cdd:PLN02985  81 RMMGEFMQPGGRFMLSKLGLEDCLEGIDAQKATGMAVYKDGKEAVAPFPVDNNNFPYEPSARSFHNGRFVQRLRQKASSL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  163 SNVRLEEGTVKSLLEEKGVVKGVTYKNKEGEETTALAPLTVVCDGCYSNLRRSLNDdNNAEIMSYIVGYISKNCRLEEPE 242
Cdd:PLN02985 161 PNVRLEEGTVKSLIEEKGVIKGVTYKNSAGEETTALAPLTVVCDGCYSNLRRSLND-NNAEVLSYQVGYISKNCRLEEPE 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  243 KLHLILSKPSFTMVYQISSTDVRCGFEVLPENFPSIANGEMSTFMKNTIVPQVPPKLRKIFLKGIDEGAHIKVVPAKRMT 322
Cdd:PLN02985 240 KLHLIMSKPSFTMLYQISSTDVRCVFEVLPDNIPSIANGEMSTFVKNTIAPQVPPKLRKIFLKGIDEGAHIKVVPTKRMS 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  323 STLSKKKGVIVLGDAFNMRHPVVASGMMVLLSDILILRRLLQPLSNLGDANKVSEVINSFYDIRKPMSATVNTLGNAFSQ 402
Cdd:PLN02985 320 ATLSDKKGVIVLGDAFNMRHPAIASGMMVLLSDILILRRLLQPLSNLGNANKVSEVIKSFYDIRKPMSATVNTLGNAFSQ 399

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  403 VLIGSTDEAKEAMRQGVYDYLCSGGFRTSGMMALLGGMNPRPLSLVYHLCAITLSSIGQLLSPFPSPLRIWHSLKLFGLA 482
Cdd:PLN02985 400 VLVASTDEAKEAMRQGCYDYLCSGGFRTSGMMALLGGMNPRPLSLIYHLCAITLSSIGHLLSPFPSPLRIWHSLRLFGLA 479

                        490       500       510
                 ....*....|....*....|....*....|....*
gi 15237903  483 MKMLVPNLKAEGVSQMLFPANAAAYHKSYMAATTL 517
Cdd:PLN02985 480 LKMLVPHLKAEGVSQMLFPANAAAYRKSYMAATAL 514
 
Name Accession Description Interval E-value
PLN02985 PLN02985
squalene monooxygenase
 3-517 0e+00

squalene monooxygenase


Pssm-ID: 178566 [Multi-domain]  Cd Length: 514  Bit Score: 1065.67  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903    3 FTHVCLWTLVAFVLTWTVFYLTNMKKKATDLADTVAEDQKDGAADVIIVGAGVGGSALAYALAKDGRRVHVIERDMREPE 82
Cdd:PLN02985   1 FTHVCLWTLLAFVLTWTVFYVTNRKKKATELADAVAEERKDGATDVIIVGAGVGGSALAYALAKDGRRVHVIERDLREPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903   83 RMMGEFMQPGGRLMLSKLGLQDCLEDIDAQKATGLAVYKDGKEADAPFPVDNNNFSYEPSARSFHNGRFVQQLRRKAFSL 162
Cdd:PLN02985  81 RMMGEFMQPGGRFMLSKLGLEDCLEGIDAQKATGMAVYKDGKEAVAPFPVDNNNFPYEPSARSFHNGRFVQRLRQKASSL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  163 SNVRLEEGTVKSLLEEKGVVKGVTYKNKEGEETTALAPLTVVCDGCYSNLRRSLNDdNNAEIMSYIVGYISKNCRLEEPE 242
Cdd:PLN02985 161 PNVRLEEGTVKSLIEEKGVIKGVTYKNSAGEETTALAPLTVVCDGCYSNLRRSLND-NNAEVLSYQVGYISKNCRLEEPE 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  243 KLHLILSKPSFTMVYQISSTDVRCGFEVLPENFPSIANGEMSTFMKNTIVPQVPPKLRKIFLKGIDEGAHIKVVPAKRMT 322
Cdd:PLN02985 240 KLHLIMSKPSFTMLYQISSTDVRCVFEVLPDNIPSIANGEMSTFVKNTIAPQVPPKLRKIFLKGIDEGAHIKVVPTKRMS 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  323 STLSKKKGVIVLGDAFNMRHPVVASGMMVLLSDILILRRLLQPLSNLGDANKVSEVINSFYDIRKPMSATVNTLGNAFSQ 402
Cdd:PLN02985 320 ATLSDKKGVIVLGDAFNMRHPAIASGMMVLLSDILILRRLLQPLSNLGNANKVSEVIKSFYDIRKPMSATVNTLGNAFSQ 399

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  403 VLIGSTDEAKEAMRQGVYDYLCSGGFRTSGMMALLGGMNPRPLSLVYHLCAITLSSIGQLLSPFPSPLRIWHSLKLFGLA 482
Cdd:PLN02985 400 VLVASTDEAKEAMRQGCYDYLCSGGFRTSGMMALLGGMNPRPLSLIYHLCAITLSSIGHLLSPFPSPLRIWHSLRLFGLA 479

                        490       500       510
                 ....*....|....*....|....*....|....*
gi 15237903  483 MKMLVPNLKAEGVSQMLFPANAAAYHKSYMAATTL 517
Cdd:PLN02985 480 LKMLVPHLKAEGVSQMLFPANAAAYRKSYMAATAL 514
SE pfam08491
Squalene epoxidase; This domain is found in squalene epoxidase (SE) and related proteins which ...
 199-473 4.67e-144

Squalene epoxidase; This domain is found in squalene epoxidase (SE) and related proteins which are found in taxonomically diverse groups of eukaryotes and also in bacteria. SE was first cloned from Saccharomyces cerevisiae where it was named ERG1. It contains a putative FAD binding site and is a key enzyme in the sterol biosynthetic pathway. Putative transmembrane regions are found to the protein's C-terminus.


Pssm-ID: 400679  Cd Length: 276  Bit Score: 414.81  E-value: 4.67e-144
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903   199 APLTVVCDGCYSNLRRSLNDdNNAEIMSYIVGYISKNCRLEEPEKLHLILSKPSFTMVYQISSTDVRCGFEVLPENFPSI 278
Cdd:pfam08491   2 APLTIVCDGCFSKFRKSLSD-NKPEVGSYFVGLILKNADLPAPNHGHVILGKPSPVLLYQISSTETRILCDYPGPKLPSI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903   279 ANGEMSTFMKNTIVPQVPPKLRKIFLKGIDEGaHIKVVPAKRMTSTLSKKKGVIVLGDAFNMRHPVVASGMMVLLSDILI 358
Cdd:pfam08491  81 ANGELKEYLKKSVAPQIPKELRPSFLAALEEG-KIRSMPNSFLPASKNRKKGLILLGDALNMRHPLTGGGMTVGLNDIVL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903   359 LRRLLQPLSNLGDANKVSEVINSFYDIRKPMSATVNTLGNAFSQVLIGSTDEAKeAMRQGVYDYLCSGGFRTSGMMALLG 438
Cdd:pfam08491 160 LRKLLGPLRDLSDREKVSKVLKSFHWKRKPYDAVINTLSIALYSLFAADSDELK-ALRKGCFDYFKLGGDCVSGPVALLS 238

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 15237903   439 GMNPRPLSLVYHLCAITLSSIGQLLSPFP---SPLRIW 473
Cdd:pfam08491 239 GLLPRPLLLFGHFFAVALYSIYQNFIPRPilgSPLALL 276
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 47-216 9.17e-16

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 78.44  E-value: 9.17e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  47 DVIIVGAGVGGSALAYALAKDGRRVHVIERDMREPERMMGEFMQPGGRLMLSKLGLqdcLEDIDA--QKATGLAVYkDGK 124
Cdd:COG0654   5 DVLIVGGGPAGLALALALARAGIRVTVVERAPPPRPDGRGIALSPRSLELLRRLGL---WDRLLArgAPIRGIRVR-DGS 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903 125 EADAPFPVDNNNFSYePSARSFHNGRFVQQLRRKAFSLsNVRLEEGT-VKSLLEEKGVVkGVTYKNkeGEETTalAPLTV 203
Cdd:COG0654  81 DGRVLARFDAAETGL-PAGLVVPRADLERALLEAARAL-GVELRFGTeVTGLEQDADGV-TVTLAD--GRTLR--ADLVV 153

                       170
                ....*....|...
gi 15237903 204 VCDGCYSNLRRSL 216
Cdd:COG0654 154 GADGARSAVRRLL 166
GG-red-SF TIGR02032
geranylgeranyl reductase family; This model represents a subfamily which includes ...
 47-216 1.02e-05

geranylgeranyl reductase family; This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 273936 [Multi-domain]  Cd Length: 295  Bit Score: 47.31  E-value: 1.02e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903    47 DVIIVGAGVGGSALAYALAKDGRRVHVIERDmREP-ERMMGEFMqPGGRLMLSKLGLQDCLEDIDaqkaTGLAVYKDGKE 125
Cdd:TIGR02032   2 DVVVVGAGPAGASAAYRLADKGLRVLLLEKK-SFPrYKPCGGAL-SPRALEELDLPGELIVNLVR----GARFFSPNGDS 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903   126 ADAPFPvdnnnfsyEPSARSFHNGRFVQQLRRKAFSLSNVRLEEGTVKSLLEEKGVVkGVTYKNKEGEETtalAPLTVVC 205
Cdd:TIGR02032  76 VEIPIE--------TELAYVIDRDAFDEQLAERAQEAGAELRLGTRVLDVEIHDDRV-VVIVRGSEGTVT---AKIVIGA 143

                         170
                  ....*....|.
gi 15237903   206 DGCYSNLRRSL 216
Cdd:TIGR02032 144 DGSRSIVAKKL 154
 
Name Accession Description Interval E-value
PLN02985 PLN02985
squalene monooxygenase
 3-517 0e+00

squalene monooxygenase


Pssm-ID: 178566 [Multi-domain]  Cd Length: 514  Bit Score: 1065.67  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903    3 FTHVCLWTLVAFVLTWTVFYLTNMKKKATDLADTVAEDQKDGAADVIIVGAGVGGSALAYALAKDGRRVHVIERDMREPE 82
Cdd:PLN02985   1 FTHVCLWTLLAFVLTWTVFYVTNRKKKATELADAVAEERKDGATDVIIVGAGVGGSALAYALAKDGRRVHVIERDLREPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903   83 RMMGEFMQPGGRLMLSKLGLQDCLEDIDAQKATGLAVYKDGKEADAPFPVDNNNFSYEPSARSFHNGRFVQQLRRKAFSL 162
Cdd:PLN02985  81 RMMGEFMQPGGRFMLSKLGLEDCLEGIDAQKATGMAVYKDGKEAVAPFPVDNNNFPYEPSARSFHNGRFVQRLRQKASSL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  163 SNVRLEEGTVKSLLEEKGVVKGVTYKNKEGEETTALAPLTVVCDGCYSNLRRSLNDdNNAEIMSYIVGYISKNCRLEEPE 242
Cdd:PLN02985 161 PNVRLEEGTVKSLIEEKGVIKGVTYKNSAGEETTALAPLTVVCDGCYSNLRRSLND-NNAEVLSYQVGYISKNCRLEEPE 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  243 KLHLILSKPSFTMVYQISSTDVRCGFEVLPENFPSIANGEMSTFMKNTIVPQVPPKLRKIFLKGIDEGAHIKVVPAKRMT 322
Cdd:PLN02985 240 KLHLIMSKPSFTMLYQISSTDVRCVFEVLPDNIPSIANGEMSTFVKNTIAPQVPPKLRKIFLKGIDEGAHIKVVPTKRMS 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  323 STLSKKKGVIVLGDAFNMRHPVVASGMMVLLSDILILRRLLQPLSNLGDANKVSEVINSFYDIRKPMSATVNTLGNAFSQ 402
Cdd:PLN02985 320 ATLSDKKGVIVLGDAFNMRHPAIASGMMVLLSDILILRRLLQPLSNLGNANKVSEVIKSFYDIRKPMSATVNTLGNAFSQ 399

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  403 VLIGSTDEAKEAMRQGVYDYLCSGGFRTSGMMALLGGMNPRPLSLVYHLCAITLSSIGQLLSPFPSPLRIWHSLKLFGLA 482
Cdd:PLN02985 400 VLVASTDEAKEAMRQGCYDYLCSGGFRTSGMMALLGGMNPRPLSLIYHLCAITLSSIGHLLSPFPSPLRIWHSLRLFGLA 479

                        490       500       510
                 ....*....|....*....|....*....|....*
gi 15237903  483 MKMLVPNLKAEGVSQMLFPANAAAYHKSYMAATTL 517
Cdd:PLN02985 480 LKMLVPHLKAEGVSQMLFPANAAAYRKSYMAATAL 514
SE pfam08491
Squalene epoxidase; This domain is found in squalene epoxidase (SE) and related proteins which ...
 199-473 4.67e-144

Squalene epoxidase; This domain is found in squalene epoxidase (SE) and related proteins which are found in taxonomically diverse groups of eukaryotes and also in bacteria. SE was first cloned from Saccharomyces cerevisiae where it was named ERG1. It contains a putative FAD binding site and is a key enzyme in the sterol biosynthetic pathway. Putative transmembrane regions are found to the protein's C-terminus.


Pssm-ID: 400679  Cd Length: 276  Bit Score: 414.81  E-value: 4.67e-144
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903   199 APLTVVCDGCYSNLRRSLNDdNNAEIMSYIVGYISKNCRLEEPEKLHLILSKPSFTMVYQISSTDVRCGFEVLPENFPSI 278
Cdd:pfam08491   2 APLTIVCDGCFSKFRKSLSD-NKPEVGSYFVGLILKNADLPAPNHGHVILGKPSPVLLYQISSTETRILCDYPGPKLPSI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903   279 ANGEMSTFMKNTIVPQVPPKLRKIFLKGIDEGaHIKVVPAKRMTSTLSKKKGVIVLGDAFNMRHPVVASGMMVLLSDILI 358
Cdd:pfam08491  81 ANGELKEYLKKSVAPQIPKELRPSFLAALEEG-KIRSMPNSFLPASKNRKKGLILLGDALNMRHPLTGGGMTVGLNDIVL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903   359 LRRLLQPLSNLGDANKVSEVINSFYDIRKPMSATVNTLGNAFSQVLIGSTDEAKeAMRQGVYDYLCSGGFRTSGMMALLG 438
Cdd:pfam08491 160 LRKLLGPLRDLSDREKVSKVLKSFHWKRKPYDAVINTLSIALYSLFAADSDELK-ALRKGCFDYFKLGGDCVSGPVALLS 238

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 15237903   439 GMNPRPLSLVYHLCAITLSSIGQLLSPFP---SPLRIW 473
Cdd:pfam08491 239 GLLPRPLLLFGHFFAVALYSIYQNFIPRPilgSPLALL 276
PTZ00367 PTZ00367
squalene epoxidase; Provisional
 12-496 2.57e-99

squalene epoxidase; Provisional


Pssm-ID: 240384 [Multi-domain]  Cd Length: 567  Bit Score: 310.63  E-value: 2.57e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903   12 VAFVLTWTVFYLTNMKKKATDLADTVAEDQKDgaADVIIVGAGVGGSALAYALAKDGRRVHVIERDMR-EPERMMGEFMQ 90
Cdd:PTZ00367   2 FFATVLCVVSTLLLLNRILSRLRFKPARTNYD--YDVIIVGGSIAGPVLAKALSKQGRKVLMLERDLFsKPDRIVGELLQ 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903   91 PGGRLMLSKLGLQDCLEDIDAQKATGLAVYKDGKEADAPFpvdnnnfSYEPSARSFHNGRFVQQLRRKAF--SLSNVRLE 168
Cdd:PTZ00367  80 PGGVNALKELGMEECAEGIGMPCFGYVVFDHKGKQVKLPY-------GAGASGVSFHFGDFVQNLRSHVFhnCQDNVTML 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  169 EGTVKSLLEEKGV----VKGVTYKNKEGEET---------------------TALAPLTVVCDGCYSNLRRSLNDDNNA- 222
Cdd:PTZ00367 153 EGTVNSLLEEGPGfserAYGVEYTEAEKYDVpenpfredppsanpsattvrkVATAPLVVMCDGGMSKFKSRYQHYTPAs 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  223 EIMSYIVGYISKNCRLEEPEKLHLILSKPSFTMVYQISSTDVRCgfeVLPENFPSIAN-GEMSTFMKNTIVPQVPPKLRK 301
Cdd:PTZ00367 233 ENHSHFVGLVLKNVRLPKEQHGTVFLGKTGPILSYRLDDNELRV---LVDYNKPTLPSlEEQSEWLIEDVAPHLPENMRE 309

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  302 IFLKGIDEGAHIKVVPAKRMTSTLSKKKGVIVLGDAFNMRHPVVASGMMVLLSDILILRRLLQPLSNL--GDANKVSEV- 378
Cdd:PTZ00367 310 SFIRASKDTKRIRSMPNARYPPAFPSIKGYVGIGDHANQRHPLTGGGMTCCFSDCIRLAKSLTGIKSLrsIDQNEMAEIe 389

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  379 ------INSFYDIRKPMSATVNTLGNAFSQVLigstdeAKEAMRQGVYDYLCSGGFRTSGMMALLGGMNPRPLSLVYHLC 452
Cdd:PTZ00367 390 daiqaaILSYARNRKTHASTINILSWALYSVF------SSPALRDACLDYFSLGGECVTGPMSLLSGLDPSPGGLLFHYF 463

                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15237903  453 AITLSSIGQLLSP-----------------------FPSPLRIWHSLKLFGLAMKMLVPNLKAEGVS 496
Cdd:PTZ00367 464 SVALYGVLNLIMEtgaysifgkqlssfekltnvasfFVDPERIKHALYLLGAATTIAAPLAKSEFVS 530
PRK07045 PRK07045
putative monooxygenase; Reviewed
 42-439 3.39e-18

putative monooxygenase; Reviewed


Pssm-ID: 136171 [Multi-domain]  Cd Length: 388  Bit Score: 86.50  E-value: 3.39e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903   42 KDGAADVIIVGAGVGGSALAYALAKDGRRVHVIERDMREPERMMGEFMQPGGRLMLSKLGLQDCLEDIDAQKATGLAVYK 121
Cdd:PRK07045   2 KNNPVDVLINGSGIAGVALAHLLGARGHSVTVVERAARNRAQNGADLLKPSGIGVVRAMGLLDDVFAAGGLRRDAMRLYH 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  122 DGKeadapfPVDNNNFSyEPSARSFHNGRFVQQLRR----KAFSLSNVRLEEGTVKSLLE--EKGVVKGVTYKNKEgeet 195
Cdd:PRK07045  82 DKE------LIASLDYR-SASALGYFILIPCEQLRRlllaKLDGLPNVRLRFETSIERIErdADGTVTSVTLSDGE---- 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  196 tALAPLTVV-CDGCYSNLRRSLNdDNNAEIMSY----IVGYISKNCRLEEPEKLHlILSKPSFTMVYQISSTDVRcgfev 270
Cdd:PRK07045 151 -RVAPTVLVgADGARSMIRDDVL-RMPAERVPYatpmAFGTIALTDSVRECNRLY-VDSNQGLAYFYPIGDQATR----- 222

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  271 LPENFPSianGEMSTFMKNTIVPQVPPKLRKIF-------LKGIDEGAHIKVVPAKRMTSTLSKKKGVIVLGDAFNMRHP 343
Cdd:PRK07045 223 LVVSFPA---DEMQGYLADTTRTKLLARLNEFVgdesadaMAAIGAGTAFPLIPLGRMNLDRYHKRNVVLLGDAAHSIHP 299

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  344 VVASGMMVLLSDILILRRLLQplSNLGDANKVSEVINSFYDIRKPMSATVNTLGNAfsqvlIGSTDEAKEAMrQGVYDYL 423
Cdd:PRK07045 300 ITGQGMNLAIEDAGELGACLD--LHLSGQIALADALERFERIRRPVNEAVISYGHA-----LATTYHDRAAL-VANFRSQ 371

                        410
                 ....*....|....*.
gi 15237903  424 CSGGFRTSgmmALLGG 439
Cdd:PRK07045 372 LQTSGRDA---AWLGA 384
PRK06185 PRK06185
FAD-dependent oxidoreductase;
46-215 1.23e-16

FAD-dependent oxidoreductase;


Pssm-ID: 235729 [Multi-domain]  Cd Length: 407  Bit Score: 81.83  E-value: 1.23e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903   46 ADVIIVGAGVGGSALAYALAKDGRRVHVIE------RDMRepermmGEFMQPGGRLMLSKLGLQDCLEDIDAQKATGLAV 119
Cdd:PRK06185   7 TDCCIVGGGPAGMMLGLLLARAGVDVTVLEkhadflRDFR------GDTVHPSTLELMDELGLLERFLELPHQKVRTLRF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  120 YKDGKEAdapFPVDnnnFSYEPSARSFhnGRFVQQ------LRRKAFSLSNVRLEEGT-VKSLLEEKGVVKGVTYKNKEG 192
Cdd:PRK06185  81 EIGGRTV---TLAD---FSRLPTPYPY--IAMMPQwdfldfLAEEASAYPNFTLRMGAeVTGLIEEGGRVTGVRARTPDG 152

                        170       180
                 ....*....|....*....|...
gi 15237903  193 EETTAlAPLTVVCDGCYSNLRRS 215
Cdd:PRK06185 153 PGEIR-ADLVVGADGRHSRVRAL 174
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 47-216 9.17e-16

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 78.44  E-value: 9.17e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  47 DVIIVGAGVGGSALAYALAKDGRRVHVIERDMREPERMMGEFMQPGGRLMLSKLGLqdcLEDIDA--QKATGLAVYkDGK 124
Cdd:COG0654   5 DVLIVGGGPAGLALALALARAGIRVTVVERAPPPRPDGRGIALSPRSLELLRRLGL---WDRLLArgAPIRGIRVR-DGS 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903 125 EADAPFPVDNNNFSYePSARSFHNGRFVQQLRRKAFSLsNVRLEEGT-VKSLLEEKGVVkGVTYKNkeGEETTalAPLTV 203
Cdd:COG0654  81 DGRVLARFDAAETGL-PAGLVVPRADLERALLEAARAL-GVELRFGTeVTGLEQDADGV-TVTLAD--GRTLR--ADLVV 153

                       170
                ....*....|...
gi 15237903 204 VCDGCYSNLRRSL 216
Cdd:COG0654 154 GADGARSAVRRLL 166
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
53-216 3.07e-14

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 73.08  E-value: 3.07e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  53 AGVGGSALAYALAKDGRRVHVIERDmREP-ERMMGEFMQPGGRLMLSKLGLQDCLEdidaQKATGLAVY-KDGKEADAPF 130
Cdd:COG0644   1 AGPAGSAAARRLARAGLSVLLLEKG-SFPgDKICGGGLLPRALEELEPLGLDEPLE----RPVRGARFYsPGGKSVELPP 75

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903 131 PvdnnnfsyEPSARSFHNGRFVQQLRRKAFSLsNVRLEEGT-VKSLLEEKGVVKgVTYKNkegeETTALAPLTVVCDGCY 209
Cdd:COG0644  76 G--------RGGGYVVDRARFDRWLAEQAEEA-GAEVRTGTrVTDVLRDDGRVV-VRTGD----GEEIRADYVVDADGAR 141


                ....*..
gi 15237903 210 SNLRRSL 216
Cdd:COG0644 142 SLLARKL 148
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
46-211 2.81e-13

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 71.09  E-value: 2.81e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  46 ADVIIVGAGVGGSALAYALAKDGRRVHVIERD---------------------------------MREPERMMGEF---- 88
Cdd:COG0665   3 ADVVVIGGGIAGLSTAYHLARRGLDVTVLERGrpgsgasgrnagqlrpglaaladralvrlareaLDLWRELAAELgidc 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  89 -MQPGGRLML--SKLGLQDCLEDIDAQKATGLAV-YKDGKEADAPFP-VDNNNF---SYEPSARSFHNGRFVQQLRRKAF 160
Cdd:COG0665  83 dFRRTGVLYLarTEAELAALRAEAEALRALGLPVeLLDAAELREREPgLGSPDYaggLYDPDDGHVDPAKLVRALARAAR 162

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|..
gi 15237903 161 SLsNVRLEEGT-VKSLLEEKGVVKGVtyknkEGEETTALAPLTVVCDGCYSN 211
Cdd:COG0665 163 AA-GVRIREGTpVTGLEREGGRVTGV-----RTERGTVRADAVVLAAGAWSA 208
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 47-212 4.51e-10

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 61.26  E-value: 4.51e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903    47 DVIIVGAGVGGSALAYALAKDGRRVHVIERDMR-------------------EPERMMGEFMQPGGRLM--LSKLGLQDC 105
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGLSVTLLERGDDpgsgasgrnaglihpglryLEPSELARLALEALDLWeeLEEELGIDC 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903   106 L-------------------EDIDAQKATGLAVYK-DGKEADAPFPVDNNNFS--YEPSARSFHNGRFVQQLRRKAFSLs 163
Cdd:pfam01266  81 GfrrcgvlvlardeeeealeKLLAALRRLGVPAELlDAEELRELEPLLPGLRGglFYPDGGHVDPARLLRALARAAEAL- 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 15237903   164 NVRLEEGT-VKSLLEEKGVVkgvtyknkeGEETTALAPLTVVCDGCYSNL 212
Cdd:pfam01266 160 GVRIIEGTeVTGIEEEGGVW---------GVVTTGEADAVVNAAGAWADL 200
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
50-76 4.20e-07

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 47.14  E-value: 4.20e-07
                          10        20
                  ....*....|....*....|....*..
gi 15237903    50 IVGAGVGGSALAYALAKDGRRVHVIER 76
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEK 27
BetA COG2303
Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General ...
 43-76 2.16e-06

Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only]; Choline dehydrogenase or related flavoprotein is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 441878 [Multi-domain]  Cd Length: 531  Bit Score: 50.21  E-value: 2.16e-06
                        10        20        30
                ....*....|....*....|....*....|....*
gi 15237903  43 DGAADVIIVGAGVGGSALAYALAKD-GRRVHVIER 76
Cdd:COG2303   2 LEEYDYVIVGAGSAGCVLANRLSEDaGLRVLLLEA 36
LhgO COG0579
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];
47-76 7.49e-06

L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];


Pssm-ID: 440344 [Multi-domain]  Cd Length: 418  Bit Score: 48.22  E-value: 7.49e-06
                        10        20        30
                ....*....|....*....|....*....|.
gi 15237903  47 DVIIVGAGVGGSALAYALAK-DGRRVHVIER 76
Cdd:COG0579   6 DVVIIGAGIVGLALARELSRyEDLKVLVLEK 36
GG-red-SF TIGR02032
geranylgeranyl reductase family; This model represents a subfamily which includes ...
 47-216 1.02e-05

geranylgeranyl reductase family; This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 273936 [Multi-domain]  Cd Length: 295  Bit Score: 47.31  E-value: 1.02e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903    47 DVIIVGAGVGGSALAYALAKDGRRVHVIERDmREP-ERMMGEFMqPGGRLMLSKLGLQDCLEDIDaqkaTGLAVYKDGKE 125
Cdd:TIGR02032   2 DVVVVGAGPAGASAAYRLADKGLRVLLLEKK-SFPrYKPCGGAL-SPRALEELDLPGELIVNLVR----GARFFSPNGDS 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903   126 ADAPFPvdnnnfsyEPSARSFHNGRFVQQLRRKAFSLSNVRLEEGTVKSLLEEKGVVkGVTYKNKEGEETtalAPLTVVC 205
Cdd:TIGR02032  76 VEIPIE--------TELAYVIDRDAFDEQLAERAQEAGAELRLGTRVLDVEIHDDRV-VVIVRGSEGTVT---AKIVIGA 143

                         170
                  ....*....|.
gi 15237903   206 DGCYSNLRRSL 216
Cdd:TIGR02032 144 DGSRSIVAKKL 154
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 47-95 1.04e-05

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 47.92  E-value: 1.04e-05
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*....
gi 15237903  47 DVIIVGAGVGGSALAYALAKDGRRVHVIERdmREpermmgefmQPGGRL 95
Cdd:COG1233   5 DVVVIGAGIGGLAAAALLARAGYRVTVLEK--ND---------TPGGRA 42
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 46-216 1.13e-05

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 47.71  E-value: 1.13e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903    46 ADVIIVGAGVGGSALAYALAKDGRRVHVIER---DMREP------ERMMGefmqpggrlMLSKLGLQD-CLEDIDAQKAT 115
Cdd:pfam01494   2 TDVLIVGGGPAGLMLALLLARAGVRVVLVERhatTSVLPrahglnQRTME---------LLRQAGLEDrILAEGVPHEGM 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903   116 GLAVYKDgkeadaPFPVDNNN-FSYEPSArsfhngrFVQQLR-----RKAFSLSNVRLEEGT-VKSLLEEKGVVKGVTYK 188
Cdd:pfam01494  73 GLAFYNT------RRRADLDFlTSPPRVT-------VYPQTElepilVEHAEARGAQVRFGTeVLSLEQDGDGVTAVVRD 139

                         170       180
                  ....*....|....*....|....*...
gi 15237903   189 NKEGEETTALAPLTVVCDGCYSNLRRSL 216
Cdd:pfam01494 140 RRDGEEYTVRAKYLVGCDGGRSPVRKTL 167
PRK08163 PRK08163
3-hydroxybenzoate 6-monooxygenase;
48-219 1.42e-05

3-hydroxybenzoate 6-monooxygenase;


Pssm-ID: 181262 [Multi-domain]  Cd Length: 396  Bit Score: 47.34  E-value: 1.42e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903   48 VIIVGAGVGGSALAYALAKDGRRVHVIER--DMREpermMGEFMQ--PGGRLMLSKLGLQDcledidaqKATGLAVYKD- 122
Cdd:PRK08163   7 VLIVGGGIGGLAAALALARQGIKVKLLEQaaEIGE----IGAGIQlgPNAFSALDALGVGE--------AARQRAVFTDh 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  123 --------GKEAdAPFPVDnnnfsyEPSARSFHNGRFV-------QQLRRKAFSLSNVRLEEGTVKSLLEEKGvvKGVTY 187
Cdd:PRK08163  75 ltmmdavdAEEV-VRIPTG------QAFRARFGNPYAVihradihLSLLEAVLDHPLVEFRTSTHVVGIEQDG--DGVTV 145

                        170       180       190
                 ....*....|....*....|....*....|..
gi 15237903  188 KNKEGEETTALAplTVVCDGCYSNLRRSLNDD 219
Cdd:PRK08163 146 FDQQGNRWTGDA--LIGCDGVKSVVRQSLVGD 175
PRK12834 PRK12834
putative FAD-binding dehydrogenase; Reviewed
 46-107 2.85e-05

putative FAD-binding dehydrogenase; Reviewed


Pssm-ID: 183782 [Multi-domain]  Cd Length: 549  Bit Score: 46.82  E-value: 2.85e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15237903   46 ADVIIVGAGVGGSALAYALAKDGRRVHVIErdmREPERMMG--EFMQPGGRLMLS-----KLGLQDCLE 107
Cdd:PRK12834   5 ADVIVVGAGLAGLVAAAELADAGKRVLLLD---QENEANLGgqAFWSLGGLFLVDspeqrRLGIKDSLE 70
PRK07494 PRK07494
UbiH/UbiF family hydroxylase;
47-119 5.02e-05

UbiH/UbiF family hydroxylase;


Pssm-ID: 181001 [Multi-domain]  Cd Length: 388  Bit Score: 45.66  E-value: 5.02e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15237903   47 DVIIVGAGVGGSALAYALAKDGRRVHVIERDMREPERMMGEFMQPGGRlMLSKLGLQDCLEDidaqKATGLAV 119
Cdd:PRK07494   9 DIAVIGGGPAGLAAAIALARAGASVALVAPEPPYADLRTTALLGPSIR-FLERLGLWARLAP----HAAPLQS 76
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 47-79 5.34e-05

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 45.59  E-value: 5.34e-05
                        10        20        30
                ....*....|....*....|....*....|...
gi 15237903  47 DVIIVGAGVGGSALAYALAKDGRRVHVIERDMR 79
Cdd:COG1232   3 RVAVIGGGIAGLTAAYRLAKAGHEVTVLEASDR 35
mnmC PRK01747
bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent ...
 47-77 1.01e-04

bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC;


Pssm-ID: 234978 [Multi-domain]  Cd Length: 662  Bit Score: 44.84  E-value: 1.01e-04
                         10        20        30
                 ....*....|....*....|....*....|.
gi 15237903   47 DVIIVGAGVGGSALAYALAKDGRRVHVIERD 77
Cdd:PRK01747 262 DAAIIGGGIAGAALALALARRGWQVTLYEAD 292
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 47-76 1.22e-04

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 44.47  E-value: 1.22e-04
                        10        20        30
                ....*....|....*....|....*....|
gi 15237903  47 DVIIVGAGVGGSALAYALAKDGRRVHVIER 76
Cdd:COG2072   8 DVVVIGAGQAGLAAAYHLRRAGIDFVVLEK 37
PRK06184 PRK06184
hypothetical protein; Provisional
 45-216 1.36e-04

hypothetical protein; Provisional


Pssm-ID: 235728 [Multi-domain]  Cd Length: 502  Bit Score: 44.59  E-value: 1.36e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903   45 AADVIIVGAGVGGSALAYALAKDGRRVHVIERdMREPER-MMGEFMQPGGRLMLSKLGLqdcLEDIDA--QKATGLAVYK 121
Cdd:PRK06184   3 TTDVLIVGAGPTGLTLAIELARRGVSFRLIEK-APEPFPgSRGKGIQPRTQEVFDDLGV---LDRVVAagGLYPPMRIYR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  122 DG---KEADAPFPVdnnnfsyEPS-ARSFHNGRFVQQLRRKAFSLSnvRLEE--GTV---KSLLEEKGVVKGVTYK-NKE 191
Cdd:PRK06184  79 DDgsvAESDMFAHL-------EPTpDEPYPLPLMVPQWRTERILRE--RLAElgHRVefgCELVGFEQDADGVTARvAGP 149

                        170       180
                 ....*....|....*....|....*
gi 15237903  192 GEETTALAPLTVVCDGCYSNLRRSL 216
Cdd:PRK06184 150 AGEETVRARYLVGADGGRSFVRKAL 174
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
46-95 1.41e-04

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 44.14  E-value: 1.41e-04
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|.
gi 15237903  46 ADVIIVGAGVGGSALAYALAKDGRRVHVIE-RDmrepermmgefmQPGGRL 95
Cdd:COG1231   8 KDVVIVGAGLAGLAAARELRKAGLDVTVLEaRD------------RVGGRV 46
PRK07233 PRK07233
hypothetical protein; Provisional
 50-77 1.44e-04

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 44.11  E-value: 1.44e-04
                         10        20
                 ....*....|....*....|....*...
gi 15237903   50 IVGAGVGGSALAYALAKDGRRVHVIERD 77
Cdd:PRK07233   4 IVGGGIAGLAAAYRLAKRGHEVTVFEAD 31
Lpd COG1249
Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex ...
 47-78 2.03e-04

Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase [Energy production and conversion]; Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase is part of the Pathway/BioSystem: Glycine cleavagePyruvate oxidation


Pssm-ID: 440861 [Multi-domain]  Cd Length: 456  Bit Score: 43.92  E-value: 2.03e-04
                        10        20        30
                ....*....|....*....|....*....|..
gi 15237903  47 DVIIVGAGVGGSALAYALAKDGRRVHVIERDM 78
Cdd:COG1249   5 DLVVIGAGPGGYVAAIRAAQLGLKVALVEKGR 36
FAD_binding_2 pfam00890
FAD binding domain; This family includes members that bind FAD. This family includes the ...
 47-76 2.99e-04

FAD binding domain; This family includes members that bind FAD. This family includes the flavoprotein subunits from succinate and fumarate dehydrogenase, aspartate oxidase and the alpha subunit of adenylylsulphate reductase.


Pssm-ID: 395718 [Multi-domain]  Cd Length: 398  Bit Score: 43.05  E-value: 2.99e-04
                          10        20        30
                  ....*....|....*....|....*....|
gi 15237903    47 DVIIVGAGVGGSALAYALAKDGRRVHVIER 76
Cdd:pfam00890   1 DVLVIGGGLAGLAAALAAAEAGLKVAVVEK 30
PRK07364 PRK07364
FAD-dependent hydroxylase;
29-75 3.49e-04

FAD-dependent hydroxylase;


Pssm-ID: 236001 [Multi-domain]  Cd Length: 415  Bit Score: 43.08  E-value: 3.49e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 15237903   29 KATDLADTVAEDQKDGAADVIIVGAGVGGSALAYALAKDGRRVHVIE 75
Cdd:PRK07364   2 TLTAATSPTLPSTRSLTYDVAIVGGGIVGLTLAAALKDSGLRIALIE 48
FadH2 COG0446
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase ...
 20-128 3.83e-04

NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism];


Pssm-ID: 440215 [Multi-domain]  Cd Length: 322  Bit Score: 42.49  E-value: 3.83e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  20 VFYLTNMkkkatDLADTVAED-QKDGAADVIIVGAGVGGSALAYALAKDGRRVHVIERD---MREPERMMGEFMQPggrl 95
Cdd:COG0446 103 VFTLRTL-----DDADALREAlKEFKGKRAVVIGGGPIGLELAEALRKRGLKVTLVERAprlLGVLDPEMAALLEE---- 173

                        90       100       110
                ....*....|....*....|....*....|....*..
gi 15237903  96 MLSKLG----LQDCLEDIDAQKATGlAVYKDGKEADA 128
Cdd:COG0446 174 ELREHGvelrLGETVVAIDGDDKVA-VTLTDGEEIPA 209
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
47-99 4.74e-04

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 42.41  E-value: 4.74e-04
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|...
gi 15237903  47 DVIIVGAGVGGSALAYALAKDGRRVHVIERdmrepermmgefMQPGGRLMLSK 99
Cdd:COG0492   2 DVVIIGAGPAGLTAAIYAARAGLKTLVIEG------------GEPGGQLATTK 42
COG3573 COG3573
Predicted oxidoreductase [General function prediction only];
46-86 4.90e-04

Predicted oxidoreductase [General function prediction only];


Pssm-ID: 442794 [Multi-domain]  Cd Length: 551  Bit Score: 42.86  E-value: 4.90e-04
                        10        20        30        40
                ....*....|....*....|....*....|....*....|.
gi 15237903  46 ADVIIVGAGVGGSALAYALAKDGRRVHVIErdmREPERMMG 86
Cdd:COG3573   6 ADVIVVGAGLAGLVAAAELADAGRRVLLLD---QEPEANLG 43
PRK09126 PRK09126
FAD-dependent hydroxylase;
47-76 5.65e-04

FAD-dependent hydroxylase;


Pssm-ID: 236385 [Multi-domain]  Cd Length: 392  Bit Score: 42.24  E-value: 5.65e-04
                         10        20        30
                 ....*....|....*....|....*....|
gi 15237903   47 DVIIVGAGVGGSALAYALAKDGRRVHVIER 76
Cdd:PRK09126   5 DIVVVGAGPAGLSFARSLAGSGLKVTLIER 34
PRK07538 PRK07538
hypothetical protein; Provisional
 47-216 5.77e-04

hypothetical protein; Provisional


Pssm-ID: 236046 [Multi-domain]  Cd Length: 413  Bit Score: 42.19  E-value: 5.77e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903   47 DVIIVGAGVGGSALAYALAKDGRRVHVIE--RDMREpermMGE--FMQPGGRLMLSKLGLQDCLEDIdAQKATGLA---- 118
Cdd:PRK07538   2 KVLIAGGGIGGLTLALTLHQRGIEVVVFEaaPELRP----LGVgiNLLPHAVRELAELGLLDALDAI-GIRTRELAyfnr 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  119 ----VYKD--GKEADAPFPvdnnnfSYepsarSFHNGRFVQQLRRKAFSlsnvRLEEGTVK------SLLEEKGVVKGVT 186
Cdd:PRK07538  77 hgqrIWSEprGLAAGYDWP------QY-----SIHRGELQMLLLDAVRE----RLGPDAVRtghrvvGFEQDADVTVVFL 141

                        170       180       190
                 ....*....|....*....|....*....|
gi 15237903  187 YKNKEGEETTALAPLTVVCDGCYSNLRRSL 216
Cdd:PRK07538 142 GDRAGGDLVSVRGDVLIGADGIHSAVRAQL 171
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 47-100 6.52e-04

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 41.92  E-value: 6.52e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 15237903    47 DVIIVGAGVGGSALAYALAKDGRRVHVIERdmrepERMMgefmqPGGRLMLSKL 100
Cdd:pfam07992   2 DVVVIGGGPAGLAAALTLAQLGGKVTLIED-----EGTC-----PYGGCVLSKA 45
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 26-90 7.52e-04

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 41.53  E-value: 7.52e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15237903    26 MKKKATDLADTVAEDQ----KDGAADVIIVGAGVGGSALAYALAKDGRRVHVIE---RDMREPERMMGEFMQ 90
Cdd:pfam07992 129 VELNVGFLVRTLDSAEalrlKLLPKRVVVVGGGYIGVELAAALAKLGKEVTLIEaldRLLRAFDEEISAALE 200
PRK05249 PRK05249
Si-specific NAD(P)(+) transhydrogenase;
47-86 7.67e-04

Si-specific NAD(P)(+) transhydrogenase;


Pssm-ID: 235373 [Multi-domain]  Cd Length: 461  Bit Score: 42.07  E-value: 7.67e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 15237903   47 DVIIVGAGVGGSALAYALAKDGRRVHVIERdmrepERMMG 86
Cdd:PRK05249   7 DLVVIGSGPAGEGAAMQAAKLGKRVAVIER-----YRNVG 41
PRK00711 PRK00711
D-amino acid dehydrogenase;
48-76 8.11e-04

D-amino acid dehydrogenase;


Pssm-ID: 234819 [Multi-domain]  Cd Length: 416  Bit Score: 41.71  E-value: 8.11e-04
                         10        20
                 ....*....|....*....|....*....
gi 15237903   48 VIIVGAGVGGSALAYALAKDGRRVHVIER 76
Cdd:PRK00711   3 VVVLGSGVIGVTSAWYLAQAGHEVTVIDR 31
ubiF PRK08020
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed
 47-81 1.22e-03

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed


Pssm-ID: 181199 [Multi-domain]  Cd Length: 391  Bit Score: 41.12  E-value: 1.22e-03
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 15237903   47 DVIIVGAGVGGSALAYALAKDGRRVHVIERDMREP 81
Cdd:PRK08020   7 DIAIVGGGMVGAALALGLAQHGFSVAVLEHAAPAP 41
FAD_oxidored pfam12831
FAD dependent oxidoreductase; This family of proteins contains FAD dependent oxidoreductases ...
 47-195 1.26e-03

FAD dependent oxidoreductase; This family of proteins contains FAD dependent oxidoreductases and related proteins.


Pssm-ID: 432816 [Multi-domain]  Cd Length: 420  Bit Score: 41.06  E-value: 1.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903    47 DVIIVGAGVGGSALAYALAKDGRRVHVIERDMRepermmgefmqPGGrLMLSKLGLQDC-LEDIDAQKATGLA------V 119
Cdd:pfam12831   1 DVVVVGGGPAGVAAAIAAARAGAKVLLVERRGF-----------LGG-MLTSGLVGPDMgFYLNKEQVVGGIArefrqrL 68

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15237903   120 YKDGkEADAPFPVDNNNFSYEPSA--RSFHNgrFVQQlrrkafslSNVRLEEGT-VKSLLEEKGVVKGVTYKNKEGEET 195
Cdd:pfam12831  69 RARG-GLPGPYGLRGGWVPFDPEVakAVLDE--MLAE--------AGVTVLLHTrVVGVVKEGGRITGVTVETKGGRIT 136
PRK07333 PRK07333
ubiquinone biosynthesis hydroxylase;
46-213 1.73e-03

ubiquinone biosynthesis hydroxylase;


Pssm-ID: 180935 [Multi-domain]  Cd Length: 403  Bit Score: 40.73  E-value: 1.73e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903   46 ADVIIVGAGVGGSALAYAL--AKDGRRVHVIE--------RDMRepermmGEFMQPGGRLMLSKLGlqdCLEDI--DAQK 113
Cdd:PRK07333   2 CDVVIAGGGYVGLALAVALkqAAPHLPVTVVDaapagawsRDPR------ASAIAAAARRMLEALG---VWDEIapEAQP 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  114 ATGLAVyKDGKEADAPFPV----DNNNFSYEPSARSFHNGRFVQQLRRKAFSLsNVRLEEGTVKSLLEEKGVVKGVTYkn 189
Cdd:PRK07333  73 ITDMVI-TDSRTSDPVRPVfltfEGEVEPGEPFAHMVENRVLINALRKRAEAL-GIDLREATSVTDFETRDEGVTVTL-- 148

                        170       180
                 ....*....|....*....|....
gi 15237903  190 keGEETTALAPLTVVCDGCYSNLR 213
Cdd:PRK07333 149 --SDGSVLEARLLVAADGARSKLR 170
PLN02576 PLN02576
protoporphyrinogen oxidase
 43-79 1.79e-03

protoporphyrinogen oxidase


Pssm-ID: 215314 [Multi-domain]  Cd Length: 496  Bit Score: 40.77  E-value: 1.79e-03
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 15237903   43 DGAADVIIVGAGVGGSALAYALA-KDGRRVHVIERDMR 79
Cdd:PLN02576  10 ASSKDVAVVGAGVSGLAAAYALAsKHGVNVLVTEARDR 47
PRK06370 PRK06370
FAD-containing oxidoreductase;
47-76 1.81e-03

FAD-containing oxidoreductase;


Pssm-ID: 235787 [Multi-domain]  Cd Length: 463  Bit Score: 40.96  E-value: 1.81e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 15237903   47 DVIIVGAGVGGSALAYALAKDGRRVHVIER 76
Cdd:PRK06370   7 DAIVIGAGQAGPPLAARAAGLGMKVALIER 36
solA PRK11259
N-methyl-L-tryptophan oxidase;
47-76 1.83e-03

N-methyl-L-tryptophan oxidase;


Pssm-ID: 236887 [Multi-domain]  Cd Length: 376  Bit Score: 40.59  E-value: 1.83e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 15237903   47 DVIIVGAGVGGSALAYALAKDGRRVHVIER 76
Cdd:PRK11259   5 DVIVIGLGSMGSAAGYYLARRGLRVLGLDR 34
PRK10015 PRK10015
oxidoreductase; Provisional
 47-95 2.31e-03

oxidoreductase; Provisional


Pssm-ID: 182194 [Multi-domain]  Cd Length: 429  Bit Score: 40.35  E-value: 2.31e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 15237903   47 DVIIVGAGVGGSALAYALAKDGRRVHVIERDMREPERMMgefmqPGGRL 95
Cdd:PRK10015   7 DAIVVGAGVAGSVAALVMARAGLDVLVIERGDSAGCKNM-----TGGRL 50
Pyr_redox pfam00070
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 48-90 2.76e-03

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 425450 [Multi-domain]  Cd Length: 80  Bit Score: 36.80  E-value: 2.76e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 15237903    48 VIIVGAGVGGSALAYALAKDGRRVHVIER---DMREPERMMGEFMQ 90
Cdd:pfam00070   2 VVVVGGGYIGLELAGALARLGSKVTVVERrdrLLPGFDPEIAKILQ 47
soxA_mon TIGR01377
sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of ...
 47-75 2.77e-03

sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms [Energy metabolism, Amino acids and amines]


Pssm-ID: 130444 [Multi-domain]  Cd Length: 380  Bit Score: 40.20  E-value: 2.77e-03
                          10        20
                  ....*....|....*....|....*....
gi 15237903    47 DVIIVGAGVGGSALAYALAKDGRRVHVIE 75
Cdd:TIGR01377   2 DVIVVGAGIMGCFAAYHLAKHGKKTLLLE 30
PRK06292 PRK06292
dihydrolipoamide dehydrogenase; Validated
 47-77 3.00e-03

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235774 [Multi-domain]  Cd Length: 460  Bit Score: 40.16  E-value: 3.00e-03
                         10        20        30
                 ....*....|....*....|....*....|.
gi 15237903   47 DVIIVGAGVGGSALAYALAKDGRRVHVIERD 77
Cdd:PRK06292   5 DVIVIGAGPAGYVAARRAAKLGKKVALIEKG 35
PRK08773 PRK08773
UbiH/UbiF family hydroxylase;
47-83 4.35e-03

UbiH/UbiF family hydroxylase;


Pssm-ID: 181552 [Multi-domain]  Cd Length: 392  Bit Score: 39.46  E-value: 4.35e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 15237903   47 DVIIVGAGVGGSALAYALAKDGRRVHVIERdmREPER 83
Cdd:PRK08773   8 DAVIVGGGVVGAACALALADAGLSVALVEG--REPPR 42
TrkA COG0569
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ...
 48-87 4.49e-03

Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 440335 [Multi-domain]  Cd Length: 296  Bit Score: 39.28  E-value: 4.49e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|
gi 15237903  48 VIIVGAGVGGSALAYALAKDGRRVHVIERDMREPERMMGE 87
Cdd:COG0569  98 VIIIGAGRVGRSLARELEEEGHDVVVIDKDPERVERLAEE 137
PRK07608 PRK07608
UbiH/UbiF family hydroxylase;
47-75 5.34e-03

UbiH/UbiF family hydroxylase;


Pssm-ID: 181057 [Multi-domain]  Cd Length: 388  Bit Score: 39.17  E-value: 5.34e-03
                         10        20
                 ....*....|....*....|....*....
gi 15237903   47 DVIIVGAGVGGSALAYALAKDGRRVHVIE 75
Cdd:PRK07608   7 DVVVVGGGLVGASLALALAQSGLRVALLA 35
PRK10157 PRK10157
putative oxidoreductase FixC; Provisional
 47-76 5.51e-03

putative oxidoreductase FixC; Provisional


Pssm-ID: 182273 [Multi-domain]  Cd Length: 428  Bit Score: 39.12  E-value: 5.51e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 15237903   47 DVIIVGAGVGGSALAYALAKDGRRVHVIER 76
Cdd:PRK10157   7 DAIIVGAGLAGSVAALVLAREGAQVLVIER 36
PRK02106 PRK02106
choline dehydrogenase; Validated
 46-75 6.15e-03

choline dehydrogenase; Validated


Pssm-ID: 235000 [Multi-domain]  Cd Length: 560  Bit Score: 39.04  E-value: 6.15e-03
                         10        20        30
                 ....*....|....*....|....*....|.
gi 15237903   46 ADVIIVGAGVGGSALAYALAKDGR-RVHVIE 75
Cdd:PRK02106   6 YDYIIIGAGSAGCVLANRLSEDPDvSVLLLE 36
Mrp COG0489
Fe-S cluster carrier ATPase, Mrp/ApbC/NBP35 family [Cell cycle control, cell division, ...
 30-111 9.81e-03

Fe-S cluster carrier ATPase, Mrp/ApbC/NBP35 family [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440255 [Multi-domain]  Cd Length: 289  Bit Score: 38.24  E-value: 9.81e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237903  30 ATDLADTVAEDQKDGAADVIIVGAGVGG-------SALAYALAKDGRRVHVIERDMREP--ERMMGEFMQPGGRLMLS-K 99
Cdd:COG0489  76 ALALLLLLLLLLLRLLLEVIAVTSGKGGegkstvaANLALALAQSGKRVLLIDADLRGPslHRMLGLENRPGLSDVLAgE 155

                        90
                ....*....|..
gi 15237903 100 LGLQDCLEDIDA 111
Cdd:COG0489 156 ASLEDVIQPTEV 167
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH