disease resistance protein (TIR-NBS-LRR class) [Arabidopsis thaliana]
disease resistance family protein( domain architecture ID 1000118)
disease resistance family protein similar to Nicotiana glutinosa TMV resistance protein N; resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via a direct or indirect interaction with this avirulence protein
List of domain hits
Name | Accession | Description | Interval | E-value | |||||||||||||||
PLN03210 super family | cl33662 | Resistant to P. syringae 6; Provisional |
1-982 | 3.37e-110 | |||||||||||||||
Resistant to P. syringae 6; Provisional The actual alignment was detected with superfamily member PLN03210: Pssm-ID: 215633 [Multi-domain] Cd Length: 1153 Bit Score: 372.67 E-value: 3.37e-110
|
|||||||||||||||||||
C-JID super family | cl45530 | C-JID domain; C-terminal jelly roll/Ig-like domain (C-JID) was defined in cryogenic electron ... |
966-1014 | 1.37e-09 | |||||||||||||||
C-JID domain; C-terminal jelly roll/Ig-like domain (C-JID) was defined in cryogenic electron microscopy (cryoEM) structures of plant intracellular immune receptors containing Toll/interleukin-1 receptor (TIR, PF01582), nucleotide-binding (NB-ARC, PF00931) and leucine-rich repeat (LRR) domains (TIR-NLRs). Structurally, the C-JID core is represented by a beta-sandwich made up of 8 to 9 beta-strands. C-JID matches the so-called post LRR domain originally detected via a set of MEME motifs. The domain showed a strong distribution bias towards TIR-NLRs of dicotyledonous plant species despite broader taxonomic distribution of TIR-NLR in plant groups. Structure-function analyses of cryoEM structures suggest that C-JID domains play a role in substrate-recognition, such as binding to effector proteins from pathogens, and thus are involved in the initiation of signaling by TIR-NLR receptors. Presence of C-JID (or post-LRR) and its importance for the function of Arabidopsis TIR-NLR RPS4 that partners with RRS1 for effector recognition suggest that C-JID has additional functions. The actual alignment was detected with superfamily member pfam20160: Pssm-ID: 466313 Cd Length: 108 Bit Score: 56.69 E-value: 1.37e-09
|
|||||||||||||||||||
Name | Accession | Description | Interval | E-value | |||||||||||||||
PLN03210 | PLN03210 | Resistant to P. syringae 6; Provisional |
1-982 | 3.37e-110 | |||||||||||||||
Resistant to P. syringae 6; Provisional Pssm-ID: 215633 [Multi-domain] Cd Length: 1153 Bit Score: 372.67 E-value: 3.37e-110
|
|||||||||||||||||||
TIR | pfam01582 | TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ... |
18-179 | 8.65e-42 | |||||||||||||||
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades. Pssm-ID: 396246 [Multi-domain] Cd Length: 165 Bit Score: 150.59 E-value: 8.65e-42
|
|||||||||||||||||||
TIR | smart00255 | Toll - interleukin 1 - resistance; |
16-150 | 8.66e-39 | |||||||||||||||
Toll - interleukin 1 - resistance; Pssm-ID: 214587 [Multi-domain] Cd Length: 140 Bit Score: 141.31 E-value: 8.66e-39
|
|||||||||||||||||||
LRR | COG4886 | Leucine-rich repeat (LRR) protein [Transcription]; |
597-894 | 8.25e-27 | |||||||||||||||
Leucine-rich repeat (LRR) protein [Transcription]; Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 114.65 E-value: 8.25e-27
|
|||||||||||||||||||
C-JID | pfam20160 | C-JID domain; C-terminal jelly roll/Ig-like domain (C-JID) was defined in cryogenic electron ... |
966-1014 | 1.37e-09 | |||||||||||||||
C-JID domain; C-terminal jelly roll/Ig-like domain (C-JID) was defined in cryogenic electron microscopy (cryoEM) structures of plant intracellular immune receptors containing Toll/interleukin-1 receptor (TIR, PF01582), nucleotide-binding (NB-ARC, PF00931) and leucine-rich repeat (LRR) domains (TIR-NLRs). Structurally, the C-JID core is represented by a beta-sandwich made up of 8 to 9 beta-strands. C-JID matches the so-called post LRR domain originally detected via a set of MEME motifs. The domain showed a strong distribution bias towards TIR-NLRs of dicotyledonous plant species despite broader taxonomic distribution of TIR-NLR in plant groups. Structure-function analyses of cryoEM structures suggest that C-JID domains play a role in substrate-recognition, such as binding to effector proteins from pathogens, and thus are involved in the initiation of signaling by TIR-NLR receptors. Presence of C-JID (or post-LRR) and its importance for the function of Arabidopsis TIR-NLR RPS4 that partners with RRS1 for effector recognition suggest that C-JID has additional functions. Pssm-ID: 466313 Cd Length: 108 Bit Score: 56.69 E-value: 1.37e-09
|
|||||||||||||||||||
Name | Accession | Description | Interval | E-value | |||||||||||||||
PLN03210 | PLN03210 | Resistant to P. syringae 6; Provisional |
1-982 | 3.37e-110 | |||||||||||||||
Resistant to P. syringae 6; Provisional Pssm-ID: 215633 [Multi-domain] Cd Length: 1153 Bit Score: 372.67 E-value: 3.37e-110
|
|||||||||||||||||||
TIR | pfam01582 | TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ... |
18-179 | 8.65e-42 | |||||||||||||||
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades. Pssm-ID: 396246 [Multi-domain] Cd Length: 165 Bit Score: 150.59 E-value: 8.65e-42
|
|||||||||||||||||||
TIR | smart00255 | Toll - interleukin 1 - resistance; |
16-150 | 8.66e-39 | |||||||||||||||
Toll - interleukin 1 - resistance; Pssm-ID: 214587 [Multi-domain] Cd Length: 140 Bit Score: 141.31 E-value: 8.66e-39
|
|||||||||||||||||||
LRR | COG4886 | Leucine-rich repeat (LRR) protein [Transcription]; |
597-894 | 8.25e-27 | |||||||||||||||
Leucine-rich repeat (LRR) protein [Transcription]; Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 114.65 E-value: 8.25e-27
|
|||||||||||||||||||
PLN03194 | PLN03194 | putative disease resistance protein; Provisional |
14-113 | 5.37e-13 | |||||||||||||||
putative disease resistance protein; Provisional Pssm-ID: 215626 [Multi-domain] Cd Length: 187 Bit Score: 68.69 E-value: 5.37e-13
|
|||||||||||||||||||
TIR_2 | pfam13676 | TIR domain; This is a family of Toll-like receptors. |
19-114 | 1.76e-12 | |||||||||||||||
TIR domain; This is a family of Toll-like receptors. Pssm-ID: 463954 [Multi-domain] Cd Length: 118 Bit Score: 65.03 E-value: 1.76e-12
|
|||||||||||||||||||
LRR | COG4886 | Leucine-rich repeat (LRR) protein [Transcription]; |
638-893 | 2.23e-12 | |||||||||||||||
Leucine-rich repeat (LRR) protein [Transcription]; Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 70.35 E-value: 2.23e-12
|
|||||||||||||||||||
NB-ARC | pfam00931 | NB-ARC domain; |
229-425 | 3.00e-10 | |||||||||||||||
NB-ARC domain; Pssm-ID: 395745 [Multi-domain] Cd Length: 245 Bit Score: 62.01 E-value: 3.00e-10
|
|||||||||||||||||||
C-JID | pfam20160 | C-JID domain; C-terminal jelly roll/Ig-like domain (C-JID) was defined in cryogenic electron ... |
966-1014 | 1.37e-09 | |||||||||||||||
C-JID domain; C-terminal jelly roll/Ig-like domain (C-JID) was defined in cryogenic electron microscopy (cryoEM) structures of plant intracellular immune receptors containing Toll/interleukin-1 receptor (TIR, PF01582), nucleotide-binding (NB-ARC, PF00931) and leucine-rich repeat (LRR) domains (TIR-NLRs). Structurally, the C-JID core is represented by a beta-sandwich made up of 8 to 9 beta-strands. C-JID matches the so-called post LRR domain originally detected via a set of MEME motifs. The domain showed a strong distribution bias towards TIR-NLRs of dicotyledonous plant species despite broader taxonomic distribution of TIR-NLR in plant groups. Structure-function analyses of cryoEM structures suggest that C-JID domains play a role in substrate-recognition, such as binding to effector proteins from pathogens, and thus are involved in the initiation of signaling by TIR-NLR receptors. Presence of C-JID (or post-LRR) and its importance for the function of Arabidopsis TIR-NLR RPS4 that partners with RRS1 for effector recognition suggest that C-JID has additional functions. Pssm-ID: 466313 Cd Length: 108 Bit Score: 56.69 E-value: 1.37e-09
|
|||||||||||||||||||
NACHT | COG5635 | Predicted NTPase, NACHT family domain [Signal transduction mechanisms]; |
84-479 | 6.70e-09 | |||||||||||||||
Predicted NTPase, NACHT family domain [Signal transduction mechanisms]; Pssm-ID: 444362 [Multi-domain] Cd Length: 935 Bit Score: 60.20 E-value: 6.70e-09
|
|||||||||||||||||||
ATPase_2 | pfam01637 | ATPase domain predominantly from Archaea; This family contain a conserved P-loop motif that is ... |
208-413 | 1.25e-05 | |||||||||||||||
ATPase domain predominantly from Archaea; This family contain a conserved P-loop motif that is involved in binding ATP. There are eukaryote members as well as archaeal members in this family. Pssm-ID: 376582 [Multi-domain] Cd Length: 222 Bit Score: 47.70 E-value: 1.25e-05
|
|||||||||||||||||||
AAA_16 | pfam13191 | AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ... |
211-317 | 7.73e-05 | |||||||||||||||
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Pssm-ID: 433025 [Multi-domain] Cd Length: 167 Bit Score: 44.42 E-value: 7.73e-05
|
|||||||||||||||||||
COG3903 | COG3903 | Predicted ATPase [General function prediction only]; |
224-364 | 1.09e-04 | |||||||||||||||
Predicted ATPase [General function prediction only]; Pssm-ID: 443109 [Multi-domain] Cd Length: 933 Bit Score: 46.55 E-value: 1.09e-04
|
|||||||||||||||||||
PRK15386 | PRK15386 | type III secretion effector GogB; |
767-910 | 2.03e-04 | |||||||||||||||
type III secretion effector GogB; Pssm-ID: 237954 [Multi-domain] Cd Length: 426 Bit Score: 45.25 E-value: 2.03e-04
|
|||||||||||||||||||
LRR_3 | pfam07725 | Leucine Rich Repeat; This Pfam entry includes some LRRs that fail to be detected by the ... |
638-657 | 5.10e-04 | |||||||||||||||
Leucine Rich Repeat; This Pfam entry includes some LRRs that fail to be detected by the pfam00560 model. Pssm-ID: 429621 [Multi-domain] Cd Length: 20 Bit Score: 38.09 E-value: 5.10e-04
|
|||||||||||||||||||
NACHT | pfam05729 | NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in ... |
227-375 | 1.53e-03 | |||||||||||||||
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931. Pssm-ID: 428606 [Multi-domain] Cd Length: 166 Bit Score: 40.75 E-value: 1.53e-03
|
|||||||||||||||||||
PLN03150 | PLN03150 | hypothetical protein; Provisional |
752-829 | 2.20e-03 | |||||||||||||||
hypothetical protein; Provisional Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 42.11 E-value: 2.20e-03
|
|||||||||||||||||||
PLN00113 | PLN00113 | leucine-rich repeat receptor-like protein kinase; Provisional |
752-887 | 3.01e-03 | |||||||||||||||
leucine-rich repeat receptor-like protein kinase; Provisional Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 41.76 E-value: 3.01e-03
|
|||||||||||||||||||
AAA_18 | pfam13238 | AAA domain; |
229-349 | 3.79e-03 | |||||||||||||||
AAA domain; Pssm-ID: 433052 [Multi-domain] Cd Length: 128 Bit Score: 38.95 E-value: 3.79e-03
|
|||||||||||||||||||
Blast search parameters | ||||
|