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Conserved domains on  [gi|15238105|ref|NP_196585|]
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annexin 7 [Arabidopsis thaliana]

Protein Classification

annexin( domain architecture ID 10446041)

annexin belongs to a family of calcium- and phospholipid-binding proteins that have been implicated in many cellular processes, including channel formation, membrane fusion, vesicle transport, and regulation of phospholipase A2 activity

CATH:  1.10.220.10
Gene Ontology:  GO:0005509|GO:0005544|GO:0048306|GO:0003723
PubMed:  15059252|1646719
SCOP:  4001063
TCDB:  1.A.31

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
 16-80 6.37e-22

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


:

Pssm-ID: 395139  Cd Length: 66  Bit Score: 87.14  E-value: 6.37e-22
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15238105    16 DAEQLYKAFKGWGTNERMIISILAHRNATQRSFIRAVYAANYNKDLLKELDRELSGDFERAVMLW 80
Cdd:pfam00191   2 DAELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
 245-310 1.26e-17

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


:

Pssm-ID: 395139  Cd Length: 66  Bit Score: 75.59  E-value: 1.26e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15238105   245 YFEKVLRQAINKLGTDEWGLTRVVTTRAEFDMERIKEEYIRRNSVPLDRAIAKDTHGDYEDILLAL 310
Cdd:pfam00191   1 YDAELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
 87-152 7.33e-16

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


:

Pssm-ID: 395139  Cd Length: 66  Bit Score: 70.97  E-value: 7.33e-16
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15238105    87 RDAYLAKESTKMFTKNNWVLVEIACTRSALELFNAKQAYQARYKTSLEEDVAYHTSGDIRKLLVPL 152
Cdd:pfam00191   1 YDAELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
 172-235 7.78e-10

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


:

Pssm-ID: 395139  Cd Length: 66  Bit Score: 54.02  E-value: 7.78e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15238105   172 AKILHEKIKEKAYADDDLIRILTTRSKAQISATLNHYKNNFGTSMSKYLKEDSENEYIQLLKAV 235
Cdd:pfam00191   3 AELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
 
Name Accession Description Interval E-value
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
 16-80 6.37e-22

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


Pssm-ID: 395139  Cd Length: 66  Bit Score: 87.14  E-value: 6.37e-22
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15238105    16 DAEQLYKAFKGWGTNERMIISILAHRNATQRSFIRAVYAANYNKDLLKELDRELSGDFERAVMLW 80
Cdd:pfam00191   2 DAELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
 245-310 1.26e-17

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


Pssm-ID: 395139  Cd Length: 66  Bit Score: 75.59  E-value: 1.26e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15238105   245 YFEKVLRQAINKLGTDEWGLTRVVTTRAEFDMERIKEEYIRRNSVPLDRAIAKDTHGDYEDILLAL 310
Cdd:pfam00191   1 YDAELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
ANX smart00335
Annexin repeats;
258-310 3.66e-16

Annexin repeats;


Pssm-ID: 197661  Cd Length: 53  Bit Score: 71.28  E-value: 3.66e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 15238105    258 GTDEWGLTRVVTTRAEFDMERIKEEYIRRNSVPLDRAIAKDTHGDYEDILLAL 310
Cdd:smart00335   1 GTDEKTLIEILASRSNAQLQAIKQAYKKRYGKDLEDDIKSETSGDFEKLLLAL 53
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
 87-152 7.33e-16

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


Pssm-ID: 395139  Cd Length: 66  Bit Score: 70.97  E-value: 7.33e-16
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15238105    87 RDAYLAKESTKMFTKNNWVLVEIACTRSALELFNAKQAYQARYKTSLEEDVAYHTSGDIRKLLVPL 152
Cdd:pfam00191   1 YDAELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
ANX smart00335
Annexin repeats;
28-80 8.43e-15

Annexin repeats;


Pssm-ID: 197661  Cd Length: 53  Bit Score: 67.43  E-value: 8.43e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 15238105     28 GTNERMIISILAHRNATQRSFIRAVYAANYNKDLLKELDRELSGDFERAVMLW 80
Cdd:smart00335   1 GTDEKTLIEILASRSNAQLQAIKQAYKKRYGKDLEDDIKSETSGDFEKLLLAL 53
ANX smart00335
Annexin repeats;
102-152 6.41e-13

Annexin repeats;


Pssm-ID: 197661  Cd Length: 53  Bit Score: 62.42  E-value: 6.41e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 15238105    102 NNWVLVEIACTRSALELFNAKQAYQARYKTSLEEDVAYHTSGDIRKLLVPL 152
Cdd:smart00335   3 DEKTLIEILASRSNAQLQAIKQAYKKRYGKDLEDDIKSETSGDFEKLLLAL 53
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
 172-235 7.78e-10

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


Pssm-ID: 395139  Cd Length: 66  Bit Score: 54.02  E-value: 7.78e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15238105   172 AKILHEKIKEKAYADDDLIRILTTRSKAQISATLNHYKNNFGTSMSKYLKEDSENEYIQLLKAV 235
Cdd:pfam00191   3 AELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
ANX smart00335
Annexin repeats;
186-235 1.13e-04

Annexin repeats;


Pssm-ID: 197661  Cd Length: 53  Bit Score: 39.31  E-value: 1.13e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 15238105    186 DDDLIRILTTRSKAQISATLNHYKNNFGTSMSKYLKEDSENEYIQLLKAV 235
Cdd:smart00335   4 EKTLIEILASRSNAQLQAIKQAYKKRYGKDLEDDIKSETSGDFEKLLLAL 53
 
Name Accession Description Interval E-value
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
 16-80 6.37e-22

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


Pssm-ID: 395139  Cd Length: 66  Bit Score: 87.14  E-value: 6.37e-22
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15238105    16 DAEQLYKAFKGWGTNERMIISILAHRNATQRSFIRAVYAANYNKDLLKELDRELSGDFERAVMLW 80
Cdd:pfam00191   2 DAELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
 245-310 1.26e-17

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


Pssm-ID: 395139  Cd Length: 66  Bit Score: 75.59  E-value: 1.26e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15238105   245 YFEKVLRQAINKLGTDEWGLTRVVTTRAEFDMERIKEEYIRRNSVPLDRAIAKDTHGDYEDILLAL 310
Cdd:pfam00191   1 YDAELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
ANX smart00335
Annexin repeats;
258-310 3.66e-16

Annexin repeats;


Pssm-ID: 197661  Cd Length: 53  Bit Score: 71.28  E-value: 3.66e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 15238105    258 GTDEWGLTRVVTTRAEFDMERIKEEYIRRNSVPLDRAIAKDTHGDYEDILLAL 310
Cdd:smart00335   1 GTDEKTLIEILASRSNAQLQAIKQAYKKRYGKDLEDDIKSETSGDFEKLLLAL 53
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
 87-152 7.33e-16

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


Pssm-ID: 395139  Cd Length: 66  Bit Score: 70.97  E-value: 7.33e-16
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15238105    87 RDAYLAKESTKMFTKNNWVLVEIACTRSALELFNAKQAYQARYKTSLEEDVAYHTSGDIRKLLVPL 152
Cdd:pfam00191   1 YDAELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
ANX smart00335
Annexin repeats;
28-80 8.43e-15

Annexin repeats;


Pssm-ID: 197661  Cd Length: 53  Bit Score: 67.43  E-value: 8.43e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 15238105     28 GTNERMIISILAHRNATQRSFIRAVYAANYNKDLLKELDRELSGDFERAVMLW 80
Cdd:smart00335   1 GTDEKTLIEILASRSNAQLQAIKQAYKKRYGKDLEDDIKSETSGDFEKLLLAL 53
ANX smart00335
Annexin repeats;
102-152 6.41e-13

Annexin repeats;


Pssm-ID: 197661  Cd Length: 53  Bit Score: 62.42  E-value: 6.41e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 15238105    102 NNWVLVEIACTRSALELFNAKQAYQARYKTSLEEDVAYHTSGDIRKLLVPL 152
Cdd:smart00335   3 DEKTLIEILASRSNAQLQAIKQAYKKRYGKDLEDDIKSETSGDFEKLLLAL 53
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
 172-235 7.78e-10

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


Pssm-ID: 395139  Cd Length: 66  Bit Score: 54.02  E-value: 7.78e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15238105   172 AKILHEKIKEKAYADDDLIRILTTRSKAQISATLNHYKNNFGTSMSKYLKEDSENEYIQLLKAV 235
Cdd:pfam00191   3 AELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
ANX smart00335
Annexin repeats;
186-235 1.13e-04

Annexin repeats;


Pssm-ID: 197661  Cd Length: 53  Bit Score: 39.31  E-value: 1.13e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 15238105    186 DDDLIRILTTRSKAQISATLNHYKNNFGTSMSKYLKEDSENEYIQLLKAV 235
Cdd:smart00335   4 EKTLIEILASRSNAQLQAIKQAYKKRYGKDLEDDIKSETSGDFEKLLLAL 53
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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