NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|15242486|ref|NP_196530|]
View 

reduced lateral root formation [Arabidopsis thaliana]

Protein Classification

cytochrome b5-like heme/steroid binding domain-containing protein( domain architecture ID 10445738)

cytochrome b5-like heme/steroid binding domain-containing protein such as cytochrome b5, a membrane-bound hemoprotein that functions as an electron carrier for several membrane-bound oxygenases and Arabidopsis thaliana steroid-binding proteins

CATH:  3.10.120.10
Gene Ontology:  GO:0097159|GO:0016020
PubMed:  12537557|7893819

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Cyt-b5 pfam00173
Cytochrome b5-like Heme/Steroid binding domain; This family includes heme binding domains from ...
 131-202 1.45e-24

Cytochrome b5-like Heme/Steroid binding domain; This family includes heme binding domains from a diverse range of proteins. This family also includes proteins that bind to steroids. The family includes progesterone receptors. Many members of this subfamily are membrane anchored by an N-terminal transmembrane alpha helix. This family also includes a domain in some chitin synthases. There is no known ligand for this domain in the chitin synthases.


:

Pssm-ID: 459698 [Multi-domain]  Cd Length: 74  Bit Score: 91.91  E-value: 1.45e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15242486   131 MDEVKKHRTGDSMWTVLKGRVYNISPYMNFHPGGVDMLMKAVGRDGTLLFNKY-HAWVNVDILLEKCLVGVLD 202
Cdd:pfam00173   2 LEELSKHNGDGDCWVAINGKVYDVTKFLKEHPGGEDVILSAAGKDATDAFEAIgHSEDAAEKLLKKYRIGELA 74
PLN03198 super family cl31981
delta6-acyl-lipid desaturase; Provisional
 61-194 3.37e-08

delta6-acyl-lipid desaturase; Provisional


The actual alignment was detected with superfamily member PLN03198:

Pssm-ID: 178739 [Multi-domain]  Cd Length: 526  Bit Score: 52.77  E-value: 3.37e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242486   61 SLSFTVTDSSSSKKQSNESSETFKTPAR---KPITRTKVPFEKgysqmdwlklTRTHPdlaglkgesnkrlipMDEVKKH 137
Cdd:PLN03198  60 SDSAAVQCISAEVQKNSNSQEAAEALAEsvvKPTRRRSSKEKK----------SKSHL---------------LSEVAAH 114

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 15242486  138 RTGDSMWTVLKGRVYNISPYMNFHPGGvDMLMKAVGRDGTLLFNKYHAWVNVDILLE 194
Cdd:PLN03198 115 NKPNDCWIVIKNKVYDVSDFAAEHPGG-SVISTYFGRDGTDAFSSFHAASTWKILQD 170
 
Name Accession Description Interval E-value
Cyt-b5 pfam00173
Cytochrome b5-like Heme/Steroid binding domain; This family includes heme binding domains from ...
 131-202 1.45e-24

Cytochrome b5-like Heme/Steroid binding domain; This family includes heme binding domains from a diverse range of proteins. This family also includes proteins that bind to steroids. The family includes progesterone receptors. Many members of this subfamily are membrane anchored by an N-terminal transmembrane alpha helix. This family also includes a domain in some chitin synthases. There is no known ligand for this domain in the chitin synthases.


Pssm-ID: 459698 [Multi-domain]  Cd Length: 74  Bit Score: 91.91  E-value: 1.45e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15242486   131 MDEVKKHRTGDSMWTVLKGRVYNISPYMNFHPGGVDMLMKAVGRDGTLLFNKY-HAWVNVDILLEKCLVGVLD 202
Cdd:pfam00173   2 LEELSKHNGDGDCWVAINGKVYDVTKFLKEHPGGEDVILSAAGKDATDAFEAIgHSEDAAEKLLKKYRIGELA 74
CYB5 COG5274
Cytochrome b involved in lipid metabolism [Energy production and conversion, Lipid transport ...
 129-201 2.12e-15

Cytochrome b involved in lipid metabolism [Energy production and conversion, Lipid transport and metabolism];


Pssm-ID: 444085 [Multi-domain]  Cd Length: 93  Bit Score: 68.53  E-value: 2.12e-15
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15242486 129 IPMDEVKKHRTGDSMWTVLKGRVYNISPYMNFHPGGVDMLMKAVGRDGTLLFNKYHAW-VNVDILLEKCLVGVL 201
Cdd:COG5274  18 YTLAEVATHNTLSDCWMAIDGNVYDLTEYIPKHPGGEAVILRWCGKDATEAFNTKHPHsPKAERLLESYRIGRL 91
PLN02252 PLN02252
nitrate reductase [NADPH]
 124-206 4.13e-14

nitrate reductase [NADPH]


Pssm-ID: 215141 [Multi-domain]  Cd Length: 888  Bit Score: 70.48  E-value: 4.13e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242486  124 SNKRLIPMDEVKKHRTGDSMWTVLKGRVYNISPYMNFHPGGVDMLMKAVGRDGTLLFNKYH---AWVnvdiLLEKCLVGV 200
Cdd:PLN02252 515 TGSKQYTMSEVRKHNSEDSCWIVVHGHVYDCTRFLKDHPGGADSILINAGTDCTEEFDAIHsdkAKK----MLEDYRIGE 590


                 ....*.
gi 15242486  201 LDDTKV 206
Cdd:PLN02252 591 LVTTGA 596
PLN03198 PLN03198
delta6-acyl-lipid desaturase; Provisional
 61-194 3.37e-08

delta6-acyl-lipid desaturase; Provisional


Pssm-ID: 178739 [Multi-domain]  Cd Length: 526  Bit Score: 52.77  E-value: 3.37e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242486   61 SLSFTVTDSSSSKKQSNESSETFKTPAR---KPITRTKVPFEKgysqmdwlklTRTHPdlaglkgesnkrlipMDEVKKH 137
Cdd:PLN03198  60 SDSAAVQCISAEVQKNSNSQEAAEALAEsvvKPTRRRSSKEKK----------SKSHL---------------LSEVAAH 114

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 15242486  138 RTGDSMWTVLKGRVYNISPYMNFHPGGvDMLMKAVGRDGTLLFNKYHAWVNVDILLE 194
Cdd:PLN03198 115 NKPNDCWIVIKNKVYDVSDFAAEHPGG-SVISTYFGRDGTDAFSSFHAASTWKILQD 170
 
Name Accession Description Interval E-value
Cyt-b5 pfam00173
Cytochrome b5-like Heme/Steroid binding domain; This family includes heme binding domains from ...
 131-202 1.45e-24

Cytochrome b5-like Heme/Steroid binding domain; This family includes heme binding domains from a diverse range of proteins. This family also includes proteins that bind to steroids. The family includes progesterone receptors. Many members of this subfamily are membrane anchored by an N-terminal transmembrane alpha helix. This family also includes a domain in some chitin synthases. There is no known ligand for this domain in the chitin synthases.


Pssm-ID: 459698 [Multi-domain]  Cd Length: 74  Bit Score: 91.91  E-value: 1.45e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15242486   131 MDEVKKHRTGDSMWTVLKGRVYNISPYMNFHPGGVDMLMKAVGRDGTLLFNKY-HAWVNVDILLEKCLVGVLD 202
Cdd:pfam00173   2 LEELSKHNGDGDCWVAINGKVYDVTKFLKEHPGGEDVILSAAGKDATDAFEAIgHSEDAAEKLLKKYRIGELA 74
CYB5 COG5274
Cytochrome b involved in lipid metabolism [Energy production and conversion, Lipid transport ...
 129-201 2.12e-15

Cytochrome b involved in lipid metabolism [Energy production and conversion, Lipid transport and metabolism];


Pssm-ID: 444085 [Multi-domain]  Cd Length: 93  Bit Score: 68.53  E-value: 2.12e-15
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15242486 129 IPMDEVKKHRTGDSMWTVLKGRVYNISPYMNFHPGGVDMLMKAVGRDGTLLFNKYHAW-VNVDILLEKCLVGVL 201
Cdd:COG5274  18 YTLAEVATHNTLSDCWMAIDGNVYDLTEYIPKHPGGEAVILRWCGKDATEAFNTKHPHsPKAERLLESYRIGRL 91
PLN02252 PLN02252
nitrate reductase [NADPH]
 124-206 4.13e-14

nitrate reductase [NADPH]


Pssm-ID: 215141 [Multi-domain]  Cd Length: 888  Bit Score: 70.48  E-value: 4.13e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242486  124 SNKRLIPMDEVKKHRTGDSMWTVLKGRVYNISPYMNFHPGGVDMLMKAVGRDGTLLFNKYH---AWVnvdiLLEKCLVGV 200
Cdd:PLN02252 515 TGSKQYTMSEVRKHNSEDSCWIVVHGHVYDCTRFLKDHPGGADSILINAGTDCTEEFDAIHsdkAKK----MLEDYRIGE 590


                 ....*.
gi 15242486  201 LDDTKV 206
Cdd:PLN02252 591 LVTTGA 596
PLN03198 PLN03198
delta6-acyl-lipid desaturase; Provisional
 61-194 3.37e-08

delta6-acyl-lipid desaturase; Provisional


Pssm-ID: 178739 [Multi-domain]  Cd Length: 526  Bit Score: 52.77  E-value: 3.37e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242486   61 SLSFTVTDSSSSKKQSNESSETFKTPAR---KPITRTKVPFEKgysqmdwlklTRTHPdlaglkgesnkrlipMDEVKKH 137
Cdd:PLN03198  60 SDSAAVQCISAEVQKNSNSQEAAEALAEsvvKPTRRRSSKEKK----------SKSHL---------------LSEVAAH 114

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 15242486  138 RTGDSMWTVLKGRVYNISPYMNFHPGGvDMLMKAVGRDGTLLFNKYHAWVNVDILLE 194
Cdd:PLN03198 115 NKPNDCWIVIKNKVYDVSDFAAEHPGG-SVISTYFGRDGTDAFSSFHAASTWKILQD 170
PLN03199 PLN03199
delta6-acyl-lipid desaturase-like protein; Provisional
 118-211 6.66e-07

delta6-acyl-lipid desaturase-like protein; Provisional


Pssm-ID: 178740 [Multi-domain]  Cd Length: 485  Bit Score: 48.88  E-value: 6.66e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242486  118 AGLKGESNKRLIPMDEVKKHRTGDSMWTVLKGRVYNISPYMNfHPGGVDMLMKAvGRDGTLLFNKYHAwVNVDILLEKCL 197
Cdd:PLN03199  15 AALKLAEKPQKISWQEVKKHASPDDAWIIHQNKVYDVSNWHD-HPGGAVIFTHA-GDDMTDIFAAFHA-PGSQALMKKFY 91

                         90
                 ....*....|....
gi 15242486  198 VGVLDDTKVKKQEP 211
Cdd:PLN03199  92 IGDLIPESTEHKDP 105
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH