NCBI Conserved Domain Search

NCBI

3D Macromolecular Structures

Conserved Domains

Conserved domains on [gi|15242437|ref|NP_196514|]

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hydroxyproline-rich glycoprotein family protein [Arabidopsis thaliana]

Protein Classification

Graphical summary

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List of domain hits

Name

Accession

Description

Interval

E-value

PspC_subgroup_2 super family

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...

36-127

2.10e-07

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.

The actual alignment was detected with superfamily member NF033839:

Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 48.23 E-value: 2.10e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242437   36 LEEPKPEIPTFPELPKPEMPKLPEFPKLELPKLPEIPKPEMPKLPEIQKPELPTFPELPKMPEFPKFDFPKLPELPKPEE 115
Cdd:NF033839 325 LEKPKPEVKPQPEKPKPEVKPQLETPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQPEKPKPEVKPQPEK 404

                         90
                 ....*....|..
gi 15242437  116 TKVPAFTMPKFP 127
Cdd:NF033839 405 PKPEVKPQPEKP 416

Name

Accession

Description

Interval

E-value

PspC_subgroup_2

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...

36-127

2.10e-07

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.

Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 48.23 E-value: 2.10e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242437   36 LEEPKPEIPTFPELPKPEMPKLPEFPKLELPKLPEIPKPEMPKLPEIQKPELPTFPELPKMPEFPKFDFPKLPELPKPEE 115
Cdd:NF033839 325 LEKPKPEVKPQPEKPKPEVKPQLETPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQPEKPKPEVKPQPEK 404

                         90
                 ....*....|..
gi 15242437  116 TKVPAFTMPKFP 127
Cdd:NF033839 405 PKPEVKPQPEKP 416

PspC_subgroup_2

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...

36-130

9.54e-07

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.

Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 46.30 E-value: 9.54e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242437   36 LEEPKPEIPTFPELPKPEMPKLPEFPKLELPKLPEIPKPEMPKLPEIQKPELPTFPELPK-----MPEFPKFDFPKLPEL 110
Cdd:NF033839 358 PEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKpevkpQPEKPKPEVKPQPEK 437

                         90       100
                 ....*....|....*....|
gi 15242437  111 PKPEETKVPAFTMPKFPGSP 130
Cdd:NF033839 438 PKPEVKPQPEKPKPEVKPQP 457

PspC_subgroup_2

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...

36-130

1.38e-06

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.

Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 45.92 E-value: 1.38e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242437   36 LEEPKPEIPTFPELPKPEMPKLPEFPKLELPKLPEIPKPEMPKLPEIQKPELPTFPELPK-----MPEFPKFDFPKLPEL 110
Cdd:NF033839 369 PEKPKPEVKPQPETPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKpevkpQPEKPKPEVKPQPEK 448

                         90       100
                 ....*....|....*....|
gi 15242437  111 PKPEETKVPAFTMPKFPGSP 130
Cdd:NF033839 449 PKPEVKPQPETPKPEVKPQP 468

PspC_subgroup_2

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...

37-127

1.39e-06

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.

Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 45.92 E-value: 1.39e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242437   37 EEPKPEIPTFPELPKPEMPKLPEFPKLELPKLPEIPKPEMPKLPEIQKPELPTFPELPKMPEFPKFDFPKLPELPKPEET 116
Cdd:NF033839 337 EKPKPEVKPQLETPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKP 416

                         90
                 ....*....|.
gi 15242437  117 KVPAFTMPKFP 127
Cdd:NF033839 417 KPEVKPQPEKP 427

PspC_subgroup_2

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...

37-130

1.70e-06

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.

Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 45.53 E-value: 1.70e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242437   37 EEPKPEIPTFPELPKPEMPKLPEFPKLELPKLPEIPKPEMPKLPEIQKPELPTFPELPKM-----PEFPKFDFPKLPELP 111
Cdd:NF033839 381 ETPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPevkpqPEKPKPEVKPQPETP 460

                         90
                 ....*....|....*....
gi 15242437  112 KPEETKVPAFTMPKFPGSP 130
Cdd:NF033839 461 KPEVKPQPEKPKPEVKPQP 479

PspC_subgroup_2

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...

36-117

2.32e-06

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.

Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 45.14 E-value: 2.32e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242437   36 LEEPKPEIPTFPELPKPEMPKLPEFPKLELPKLPEIPKPEMPKLPEIQKPELPTFPELPKMPEFPKFDFPKLPELPKPEE 115
Cdd:NF033839 347 LETPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEK 426


                 ..
gi 15242437  116 TK 117
Cdd:NF033839 427 PK 428

PspC_subgroup_2

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...

36-130

1.11e-05

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.

Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 43.22 E-value: 1.11e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242437   36 LEEPKPEIPTFPELPKPEMPKLPEFPKLELPKLPEIPKPEMPKLPEIQKPELPTFPELPK-----MPEFPKFDFPKLPEL 110
Cdd:NF033839 314 PETPKPEVKPQLEKPKPEVKPQPEKPKPEVKPQLETPKPEVKPQPEKPKPEVKPQPEKPKpevkpQPETPKPEVKPQPEK 393

                         90       100
                 ....*....|....*....|
gi 15242437  111 PKPEETKVPAFTMPKFPGSP 130
Cdd:NF033839 394 PKPEVKPQPEKPKPEVKPQP 413

PspC_subgroup_2

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...

37-117

1.17e-05

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.

Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 43.22 E-value: 1.17e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242437   37 EEPKPEIPTFPELPKPEMPKLPEFPKLELPKLPEIPKPEMPKLPEIQKPELPTFPELPK-----MPEFPKFDFPKLPELP 111
Cdd:NF033839 403 EKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPETPKpevkpQPEKPKPEVKPQPEKP 482


                 ....*.
gi 15242437  112 KPEETK 117
Cdd:NF033839 483 KPDNSK 488

PspC_subgroup_2

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...

37-130

1.77e-05

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.

Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 42.83 E-value: 1.77e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242437   37 EEPKPEIPTFPELPKPEMPKLPEFPKLELPKLPEIPKPEMPKLPEIQKPELPTFPELPK-----MPEFPKFDFPKLPELP 111
Cdd:NF033839 304 QPEKKEVKPEPETPKPEVKPQLEKPKPEVKPQPEKPKPEVKPQLETPKPEVKPQPEKPKpevkpQPEKPKPEVKPQPETP 383

                         90
                 ....*....|....*....
gi 15242437  112 KPEETKVPAFTMPKFPGSP 130
Cdd:NF033839 384 KPEVKPQPEKPKPEVKPQP 402

PspC_subgroup_2

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...

36-114

1.98e-05

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.

Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 42.45 E-value: 1.98e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242437   36 LEEPKPEIPTFPELPKPEMPKLPEFPKLELPKLPEIPKPEMPKLPEIQKPELPTFPELPK-----MPEFPKFDFPKLPEL 110
Cdd:NF033839 391 PEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKpevkpQPETPKPEVKPQPEK 470


                 ....
gi 15242437  111 PKPE 114
Cdd:NF033839 471 PKPE 474

PspC_subgroup_2

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...

36-122

3.11e-05

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.

Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 42.06 E-value: 3.11e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242437   36 LEEPKPEIPTFPELPKPEMPKLPEFPKLELPKLPEIPKPEMPKLPEIQKPELPTFPELPKMPEFPKFDFPKLPELPKPEE 115
Cdd:NF033839 413 PEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQPEKPKPEVKPQPEKPKPDNSKPQAD 492


                 ....*..
gi 15242437  116 TKVPAFT 122
Cdd:NF033839 493 DKKPSTP 499

PspC_subgroup_1

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...

37-101

1.15e-04

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.

Pssm-ID: 468201 [Multi-domain] Cd Length: 684 Bit Score: 40.38 E-value: 1.15e-04

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15242437   37 EEPKPEIPTFPELPKPEMPKLPEFPKLELPKLPEIPKPEMPKLPEIQKP---ELPTFPELPKMPEFPK 101
Cdd:NF033838 418 EQPQPAPAPQPEKPAPKPEKPAEQPKAEKPADQQAEEDYARRSEEEYNRltqQQPPKTEKPAQPSTPK 485

PspC_subgroup_2

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...

37-130

1.91e-04

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.

Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 39.75 E-value: 1.91e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242437   37 EEPKPEIPTFPELPKPEMPKLPEFPKLELPKLPEIPKPEMPKLPEIQKPELPTFPELPK-----MPEFPKFDFPKLPELP 111
Cdd:NF033839 282 DTPKEPGNKKPSAPKPGMQPSPQPEKKEVKPEPETPKPEVKPQLEKPKPEVKPQPEKPKpevkpQLETPKPEVKPQPEKP 361

                         90
                 ....*....|....*....
gi 15242437  112 KPEETKVPAFTMPKFPGSP 130
Cdd:NF033839 362 KPEVKPQPEKPKPEVKPQP 380

PspC_subgroup_2

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...

36-127

2.23e-04

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.

Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 39.37 E-value: 2.23e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242437   36 LEEPKPEIPTFPELPKPEMPKLPEFPKLELPKLPEIPKPEMPKLPEIQKPELPTFPELPKMPEFPKFDFPKLPELPKPEE 115
Cdd:NF033839 292 PSAPKPGMQPSPQPEKKEVKPEPETPKPEVKPQLEKPKPEVKPQPEKPKPEVKPQLETPKPEVKPQPEKPKPEVKPQPEK 371

                         90
                 ....*....|..
gi 15242437  116 TKVPAFTMPKFP 127
Cdd:NF033839 372 PKPEVKPQPETP 383

PTZ00449

104 kDa microneme/rhoptry antigen; Provisional

41-109

3.09e-03

104 kDa microneme/rhoptry antigen; Provisional

Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 36.21 E-value: 3.09e-03

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15242437   41 PEIPTFPELPK-PEMPKLPEFPKL-ELPKLPEIP-KPEMPKLPEiqKPELPTFPELPKMPEFPKFDF-PKLPE 109
Cdd:PTZ00449 603 AQRPTRPKSPKlPELLDIPKSPKRpESPKSPKRPpPPQRPSSPE--RPEGPKIIKSPKPPKSPKPPFdPKFKE 673

Name

Accession

Description

Interval

E-value

PspC_subgroup_2

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...

36-127

2.10e-07

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.

Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 48.23 E-value: 2.10e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242437   36 LEEPKPEIPTFPELPKPEMPKLPEFPKLELPKLPEIPKPEMPKLPEIQKPELPTFPELPKMPEFPKFDFPKLPELPKPEE 115
Cdd:NF033839 325 LEKPKPEVKPQPEKPKPEVKPQLETPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQPEKPKPEVKPQPEK 404

                         90
                 ....*....|..
gi 15242437  116 TKVPAFTMPKFP 127
Cdd:NF033839 405 PKPEVKPQPEKP 416

PspC_subgroup_2

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...

36-130

9.54e-07

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.

Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 46.30 E-value: 9.54e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242437   36 LEEPKPEIPTFPELPKPEMPKLPEFPKLELPKLPEIPKPEMPKLPEIQKPELPTFPELPK-----MPEFPKFDFPKLPEL 110
Cdd:NF033839 358 PEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKpevkpQPEKPKPEVKPQPEK 437

                         90       100
                 ....*....|....*....|
gi 15242437  111 PKPEETKVPAFTMPKFPGSP 130
Cdd:NF033839 438 PKPEVKPQPEKPKPEVKPQP 457

PspC_subgroup_2

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...

36-130

1.38e-06

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.

Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 45.92 E-value: 1.38e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242437   36 LEEPKPEIPTFPELPKPEMPKLPEFPKLELPKLPEIPKPEMPKLPEIQKPELPTFPELPK-----MPEFPKFDFPKLPEL 110
Cdd:NF033839 369 PEKPKPEVKPQPETPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKpevkpQPEKPKPEVKPQPEK 448

                         90       100
                 ....*....|....*....|
gi 15242437  111 PKPEETKVPAFTMPKFPGSP 130
Cdd:NF033839 449 PKPEVKPQPETPKPEVKPQP 468

PspC_subgroup_2

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...

37-127

1.39e-06

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.

Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 45.92 E-value: 1.39e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242437   37 EEPKPEIPTFPELPKPEMPKLPEFPKLELPKLPEIPKPEMPKLPEIQKPELPTFPELPKMPEFPKFDFPKLPELPKPEET 116
Cdd:NF033839 337 EKPKPEVKPQLETPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKP 416

                         90
                 ....*....|.
gi 15242437  117 KVPAFTMPKFP 127
Cdd:NF033839 417 KPEVKPQPEKP 427

PspC_subgroup_2

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...

37-130

1.70e-06

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.

Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 45.53 E-value: 1.70e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242437   37 EEPKPEIPTFPELPKPEMPKLPEFPKLELPKLPEIPKPEMPKLPEIQKPELPTFPELPKM-----PEFPKFDFPKLPELP 111
Cdd:NF033839 381 ETPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPevkpqPEKPKPEVKPQPETP 460

                         90
                 ....*....|....*....
gi 15242437  112 KPEETKVPAFTMPKFPGSP 130
Cdd:NF033839 461 KPEVKPQPEKPKPEVKPQP 479

PspC_subgroup_2

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...

36-117

2.32e-06

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.

Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 45.14 E-value: 2.32e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242437   36 LEEPKPEIPTFPELPKPEMPKLPEFPKLELPKLPEIPKPEMPKLPEIQKPELPTFPELPKMPEFPKFDFPKLPELPKPEE 115
Cdd:NF033839 347 LETPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEK 426


                 ..
gi 15242437  116 TK 117
Cdd:NF033839 427 PK 428

PspC_subgroup_2

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...

36-130

1.11e-05

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.

Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 43.22 E-value: 1.11e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242437   36 LEEPKPEIPTFPELPKPEMPKLPEFPKLELPKLPEIPKPEMPKLPEIQKPELPTFPELPK-----MPEFPKFDFPKLPEL 110
Cdd:NF033839 314 PETPKPEVKPQLEKPKPEVKPQPEKPKPEVKPQLETPKPEVKPQPEKPKPEVKPQPEKPKpevkpQPETPKPEVKPQPEK 393

                         90       100
                 ....*....|....*....|
gi 15242437  111 PKPEETKVPAFTMPKFPGSP 130
Cdd:NF033839 394 PKPEVKPQPEKPKPEVKPQP 413

PspC_subgroup_2

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...

37-117

1.17e-05

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.

Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 43.22 E-value: 1.17e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242437   37 EEPKPEIPTFPELPKPEMPKLPEFPKLELPKLPEIPKPEMPKLPEIQKPELPTFPELPK-----MPEFPKFDFPKLPELP 111
Cdd:NF033839 403 EKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPETPKpevkpQPEKPKPEVKPQPEKP 482


                 ....*.
gi 15242437  112 KPEETK 117
Cdd:NF033839 483 KPDNSK 488

PspC_subgroup_2

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...

37-130

1.77e-05

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.

Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 42.83 E-value: 1.77e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242437   37 EEPKPEIPTFPELPKPEMPKLPEFPKLELPKLPEIPKPEMPKLPEIQKPELPTFPELPK-----MPEFPKFDFPKLPELP 111
Cdd:NF033839 304 QPEKKEVKPEPETPKPEVKPQLEKPKPEVKPQPEKPKPEVKPQLETPKPEVKPQPEKPKpevkpQPEKPKPEVKPQPETP 383

                         90
                 ....*....|....*....
gi 15242437  112 KPEETKVPAFTMPKFPGSP 130
Cdd:NF033839 384 KPEVKPQPEKPKPEVKPQP 402

PspC_subgroup_2

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...

36-114

1.98e-05

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.

Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 42.45 E-value: 1.98e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242437   36 LEEPKPEIPTFPELPKPEMPKLPEFPKLELPKLPEIPKPEMPKLPEIQKPELPTFPELPK-----MPEFPKFDFPKLPEL 110
Cdd:NF033839 391 PEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKpevkpQPETPKPEVKPQPEK 470


                 ....
gi 15242437  111 PKPE 114
Cdd:NF033839 471 PKPE 474

PspC_subgroup_2

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...

36-122

3.11e-05

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.

Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 42.06 E-value: 3.11e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242437   36 LEEPKPEIPTFPELPKPEMPKLPEFPKLELPKLPEIPKPEMPKLPEIQKPELPTFPELPKMPEFPKFDFPKLPELPKPEE 115
Cdd:NF033839 413 PEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQPEKPKPEVKPQPEKPKPDNSKPQAD 492


                 ....*..
gi 15242437  116 TKVPAFT 122
Cdd:NF033839 493 DKKPSTP 499

PspC_subgroup_1

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...

37-101

1.15e-04

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.

Pssm-ID: 468201 [Multi-domain] Cd Length: 684 Bit Score: 40.38 E-value: 1.15e-04

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15242437   37 EEPKPEIPTFPELPKPEMPKLPEFPKLELPKLPEIPKPEMPKLPEIQKP---ELPTFPELPKMPEFPK 101
Cdd:NF033838 418 EQPQPAPAPQPEKPAPKPEKPAEQPKAEKPADQQAEEDYARRSEEEYNRltqQQPPKTEKPAQPSTPK 485

PspC_subgroup_2

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...

37-130

1.91e-04

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.

Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 39.75 E-value: 1.91e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242437   37 EEPKPEIPTFPELPKPEMPKLPEFPKLELPKLPEIPKPEMPKLPEIQKPELPTFPELPK-----MPEFPKFDFPKLPELP 111
Cdd:NF033839 282 DTPKEPGNKKPSAPKPGMQPSPQPEKKEVKPEPETPKPEVKPQLEKPKPEVKPQPEKPKpevkpQLETPKPEVKPQPEKP 361

                         90
                 ....*....|....*....
gi 15242437  112 KPEETKVPAFTMPKFPGSP 130
Cdd:NF033839 362 KPEVKPQPEKPKPEVKPQP 380

PspC_subgroup_2

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...

36-127

2.23e-04

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.

Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 39.37 E-value: 2.23e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242437   36 LEEPKPEIPTFPELPKPEMPKLPEFPKLELPKLPEIPKPEMPKLPEIQKPELPTFPELPKMPEFPKFDFPKLPELPKPEE 115
Cdd:NF033839 292 PSAPKPGMQPSPQPEKKEVKPEPETPKPEVKPQLEKPKPEVKPQPEKPKPEVKPQLETPKPEVKPQPEKPKPEVKPQPEK 371

                         90
                 ....*....|..
gi 15242437  116 TKVPAFTMPKFP 127
Cdd:NF033839 372 PKPEVKPQPETP 383

PTZ00449

104 kDa microneme/rhoptry antigen; Provisional

41-109

3.09e-03

104 kDa microneme/rhoptry antigen; Provisional

Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 36.21 E-value: 3.09e-03

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15242437   41 PEIPTFPELPK-PEMPKLPEFPKL-ELPKLPEIP-KPEMPKLPEiqKPELPTFPELPKMPEFPKFDF-PKLPE 109
Cdd:PTZ00449 603 AQRPTRPKSPKlPELLDIPKSPKRpESPKSPKRPpPPQRPSSPE--RPEGPKIIKSPKPPKSPKPPFdPKFKE 673

Blast search parameters

Data Source:	Precalculated data, version = cdd.v.3.21
Preset Options:	Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01

References:

Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.

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of the residues that compose this conserved feature have been mapped to the query sequence.

Click on the triangle to view details about the feature, including a multiple sequence alignment of your query sequence and the protein sequences used to curate the domain model, where hash marks (#) above the aligned sequences show the location of the conserved feature residues.

The thumbnail image, if present, provides an approximate view of the feature's location in 3 dimensions. Click on the triangle for interactive 3D structure viewing options.

Functional characterization of the conserved domain architecture found on the query. Click here to see more details.

This image shows a graphical summary of conserved domains identified on the query sequence. The Show Concise/Full Display button at the top of the page can be used to select the desired level of detail: only top scoring hits (labeled illustration) or all hits (labeled illustration).
Domains are color coded according to superfamilies to which they have been assigned. Hits with scores that pass a domain-specific threshold (specific hits) are drawn in bright colors. Others (non-specific hits) and superfamily placeholders are drawn in pastel colors.
if a domain or superfamily has been annotated with functional sites (conserved features), they are mapped to the query sequence and indicated through sets of triangles with the same color and shade of the domain or superfamily that provides the annotation.
Mouse over the colored bars or triangles to see descriptions of the domains and features. click on the bars or triangles to view your query sequence embedded in a multiple sequence alignment of the proteins used to develop the corresponding domain model.

The table lists conserved domains identified on the query sequence. Click on the plus sign (+) on the left to display full descriptions, alignments, and scores. Click on the domain model's accession number to view the multiple sequence alignment of the proteins used to develop the corresponding domain model.

To view your query sequence embedded in that multiple sequence alignment, click on the colored bars in the Graphical Summary portion of the search results page, or click on the triangles, if present, that represent functional sites (conserved features) mapped to the query sequence.

Concise Display shows only the best scoring domain model, in each hit category listed below except non-specific hits, for each region on the query sequence. (labeled illustration)
Standard Display shows only the best scoring domain model from each source, in each hit category listed below for each region on the query sequence. (labeled illustration)
Full Display shows all domain models, in each hit category below, that meet or exceed the RPS-BLAST threshold for statistical significance. (labeled illustration)
Four types of hits can be shown, as available, for each region on the query sequence:

specific hits meet or exceed a domain-specific e-value threshold (illustrated example) and represent a very high confidence that the query sequence belongs to the same protein family as the sequences use to create the domain model
non-specific hits meet or exceed the RPS-BLAST threshold for statistical significance (default E-value cutoff of 0.01, or an E-value selected by user via the advanced search options)
the domain superfamily to which the specific and non-specific hits belong
multi-domain models that were computationally detected and are likely to contain multiple single domains

The CD-Search help document provides more detail about the tool and its features.

Retrieve proteins that contain one or more of the domains present in the query sequence, using the Conserved Domain Architecture Retrieval Tool (CDART).

Modify your query to search against a different database and/or use advanced search options