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Conserved domains on  [gi|15237607|ref|NP_196026|]
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S-adenosyl-L-methionine-dependent methyltransferases superfamily protein [Arabidopsis thaliana]

Protein Classification

class I SAM-dependent methyltransferase( domain architecture ID 12042358)

class I SAM-dependent methyltransferase catalyzes the methylation of one or more specific substrates using S-adenosyl-L-methionine (SAM or AdoMet) as the methyl donor; similar to Arabidopsis thaliana methyltransferase PMTs

CATH:  2.20.25.110
EC:  2.1.1.-
Gene Ontology:  GO:0032259|GO:0008757|GO:0008168|GO:1904047
PubMed:  12504684|12826405
SCOP:  3000118

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Methyltransf_29 pfam03141
Putative S-adenosyl-L-methionine-dependent methyltransferase; This family is a putative ...
 92-594 0e+00

Putative S-adenosyl-L-methionine-dependent methyltransferase; This family is a putative S-adenosyl-L-methionine (SAM)-dependent methyltransferase.


:

Pssm-ID: 335237 [Multi-domain]  Cd Length: 506  Bit Score: 833.11  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607    92 EYIPCHNVTYVQQLLPSLnlSRREELERHCPPLEQRLFCLVPPPKDYKIPIRWPTSRDYVWRSNVNHTHLAEVKGGQNWV 171
Cdd:pfam03141   1 DYIPCLDNKRAIKFLLSR--ERMEHRERHCPPPEEKLNCLVPPPDGYKTPIPWPKSRDKVWYANVPHTKLAEEKGGQNWV 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607   172 HEQGQLWWFPGGGTHFKHGAPEYIQRLGNMTTNETgdlLSAGVEQVLDVGCGVASFAAYLLPLGIKTMSFAPKDGHENQI 251
Cdd:pfam03141  79 KVEGDKFTFPGGGTQFPHGADQYIDFIAQMIPDIA---WGGRVRTALDVGCGVASFGAYLLSRDVLTMSFAPKDVHEAQV 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607   252 QFALERGIRAMISAIATKQMPYPAASFDMVHCSRCRVDWHENDGVLMKEVNRLLRPNGYFVYSAPPAY-RKDKDFPVIWD 330
Cdd:pfam03141 156 QFALERGIPAMLGVLGTKRLPYPSRSFDLAHCSRCRIPWTANDGILLLEVDRVLRPGGYFVLSGPPVYaRTEEDLQEIWK 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607   331 KLVNLTSAMCWKLISRKVQTAIWVKEDDEACLRKNAELELITICGVEDVSKASWKVPLRDCV-----DISENRQQKPSSL 405
Cdd:pfam03141 236 EMEDLTKSLCWKLVAKKGDIAIWQKPLNNSCYNKREPGKKPPLCKDSDDPDAAWYVPMEACItplpeVSHEVGGGWPEPW 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607   406 TDRLSSYPTSLRE---KGISEDEFTLDTNFWREQVNQYWELMN--VNKTEVRNVMDTNAFIGGFAAAMNSYPLWVMNVVP 480
Cdd:pfam03141 316 PARLTAVPPRLSSgqiGGVSPESFKADTELWKKRVNKYKRLLKlgIDWGKVRNVMDMNAGFGGFAAALIDLPVWVMNVVP 395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607   481 ATMNDTLSGIYQRGLTGAYHDWCEPFSTYPRTYDLLHADHLFTHYKiygEGCLLEDIMLEMDRIIRPQGFIIIRDEESIV 560
Cdd:pfam03141 396 VDSPNTLPVIYDRGLIGIYHDWCEAFSTYPRTYDLLHADHLFSLYK---KRCNLVDILLEMDRILRPEGFVIIRDSVDVL 472

                         490       500       510
                  ....*....|....*....|....*....|....
gi 15237607   561 SRVRDLAPKFLWEVEAHELQDKYKKTETVLFCRK 594
Cdd:pfam03141 473 DKVKKIAKAMRWEVRMTDTEDGPHVPEKILIAQK 506
 
Name Accession Description Interval E-value
Methyltransf_29 pfam03141
Putative S-adenosyl-L-methionine-dependent methyltransferase; This family is a putative ...
 92-594 0e+00

Putative S-adenosyl-L-methionine-dependent methyltransferase; This family is a putative S-adenosyl-L-methionine (SAM)-dependent methyltransferase.


Pssm-ID: 335237 [Multi-domain]  Cd Length: 506  Bit Score: 833.11  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607    92 EYIPCHNVTYVQQLLPSLnlSRREELERHCPPLEQRLFCLVPPPKDYKIPIRWPTSRDYVWRSNVNHTHLAEVKGGQNWV 171
Cdd:pfam03141   1 DYIPCLDNKRAIKFLLSR--ERMEHRERHCPPPEEKLNCLVPPPDGYKTPIPWPKSRDKVWYANVPHTKLAEEKGGQNWV 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607   172 HEQGQLWWFPGGGTHFKHGAPEYIQRLGNMTTNETgdlLSAGVEQVLDVGCGVASFAAYLLPLGIKTMSFAPKDGHENQI 251
Cdd:pfam03141  79 KVEGDKFTFPGGGTQFPHGADQYIDFIAQMIPDIA---WGGRVRTALDVGCGVASFGAYLLSRDVLTMSFAPKDVHEAQV 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607   252 QFALERGIRAMISAIATKQMPYPAASFDMVHCSRCRVDWHENDGVLMKEVNRLLRPNGYFVYSAPPAY-RKDKDFPVIWD 330
Cdd:pfam03141 156 QFALERGIPAMLGVLGTKRLPYPSRSFDLAHCSRCRIPWTANDGILLLEVDRVLRPGGYFVLSGPPVYaRTEEDLQEIWK 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607   331 KLVNLTSAMCWKLISRKVQTAIWVKEDDEACLRKNAELELITICGVEDVSKASWKVPLRDCV-----DISENRQQKPSSL 405
Cdd:pfam03141 236 EMEDLTKSLCWKLVAKKGDIAIWQKPLNNSCYNKREPGKKPPLCKDSDDPDAAWYVPMEACItplpeVSHEVGGGWPEPW 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607   406 TDRLSSYPTSLRE---KGISEDEFTLDTNFWREQVNQYWELMN--VNKTEVRNVMDTNAFIGGFAAAMNSYPLWVMNVVP 480
Cdd:pfam03141 316 PARLTAVPPRLSSgqiGGVSPESFKADTELWKKRVNKYKRLLKlgIDWGKVRNVMDMNAGFGGFAAALIDLPVWVMNVVP 395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607   481 ATMNDTLSGIYQRGLTGAYHDWCEPFSTYPRTYDLLHADHLFTHYKiygEGCLLEDIMLEMDRIIRPQGFIIIRDEESIV 560
Cdd:pfam03141 396 VDSPNTLPVIYDRGLIGIYHDWCEAFSTYPRTYDLLHADHLFSLYK---KRCNLVDILLEMDRILRPEGFVIIRDSVDVL 472

                         490       500       510
                  ....*....|....*....|....*....|....
gi 15237607   561 SRVRDLAPKFLWEVEAHELQDKYKKTETVLFCRK 594
Cdd:pfam03141 473 DKVKKIAKAMRWEVRMTDTEDGPHVPEKILIAQK 506
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 215-312 1.43e-09

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 56.54  E-value: 1.43e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607 215 EQVLDVGCGVASFAAYLLPLGIKTMSFapkDGHENQIQFALERGIRAMISAIATK----QMPYPAASFDMVHCSRCrVDW 290
Cdd:COG2226  24 ARVLDLGCGTGRLALALAERGARVTGV---DISPEMLELARERAAEAGLNVEFVVgdaeDLPFPDGSFDLVISSFV-LHH 99

                        90       100
                ....*....|....*....|..
gi 15237607 291 HENDGVLMKEVNRLLRPNGYFV 312
Cdd:COG2226 100 LPDPERALAEIARVLKPGGRLV 121
PRK08317 PRK08317
hypothetical protein; Provisional
 215-316 1.93e-03

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 40.31  E-value: 1.93e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607  215 EQVLDVGCG----VASFAAYLLP----LGIktmsfapkDGHENQIQFALER-----GIRAMISAIATkQMPYPAASFDMV 281
Cdd:PRK08317  21 DRVLDVGCGpgndARELARRVGPegrvVGI--------DRSEAMLALAKERaaglgPNVEFVRGDAD-GLPFPDGSFDAV 91

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 15237607  282 hCSrCRVDWH-ENDGVLMKEVNRLLRPNGYFVYSAP 316
Cdd:PRK08317  92 -RS-DRVLQHlEDPARALAEIARVLRPGGRVVVLDT 125
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 217-314 3.41e-03

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 37.41  E-value: 3.41e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607 217 VLDVGCGVASFAAYLLPLGIK--TMSfapkDGHENQIQFALERGIRAMISAI------ATKQMPYPAASFDMVHCSRCRV 288
Cdd:cd02440   2 VLDLGCGTGALALALASGPGArvTGV----DISPVALELARKAAAALLADNVevlkgdAEELPPEADESFDVIISDPPLH 77

                        90       100
                ....*....|....*....|....*.
gi 15237607 289 DWHENDGVLMKEVNRLLRPNGYFVYS 314
Cdd:cd02440  78 HLVEDLARFLEEARRLLKPGGVLVLT 103
 
Name Accession Description Interval E-value
Methyltransf_29 pfam03141
Putative S-adenosyl-L-methionine-dependent methyltransferase; This family is a putative ...
 92-594 0e+00

Putative S-adenosyl-L-methionine-dependent methyltransferase; This family is a putative S-adenosyl-L-methionine (SAM)-dependent methyltransferase.


Pssm-ID: 335237 [Multi-domain]  Cd Length: 506  Bit Score: 833.11  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607    92 EYIPCHNVTYVQQLLPSLnlSRREELERHCPPLEQRLFCLVPPPKDYKIPIRWPTSRDYVWRSNVNHTHLAEVKGGQNWV 171
Cdd:pfam03141   1 DYIPCLDNKRAIKFLLSR--ERMEHRERHCPPPEEKLNCLVPPPDGYKTPIPWPKSRDKVWYANVPHTKLAEEKGGQNWV 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607   172 HEQGQLWWFPGGGTHFKHGAPEYIQRLGNMTTNETgdlLSAGVEQVLDVGCGVASFAAYLLPLGIKTMSFAPKDGHENQI 251
Cdd:pfam03141  79 KVEGDKFTFPGGGTQFPHGADQYIDFIAQMIPDIA---WGGRVRTALDVGCGVASFGAYLLSRDVLTMSFAPKDVHEAQV 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607   252 QFALERGIRAMISAIATKQMPYPAASFDMVHCSRCRVDWHENDGVLMKEVNRLLRPNGYFVYSAPPAY-RKDKDFPVIWD 330
Cdd:pfam03141 156 QFALERGIPAMLGVLGTKRLPYPSRSFDLAHCSRCRIPWTANDGILLLEVDRVLRPGGYFVLSGPPVYaRTEEDLQEIWK 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607   331 KLVNLTSAMCWKLISRKVQTAIWVKEDDEACLRKNAELELITICGVEDVSKASWKVPLRDCV-----DISENRQQKPSSL 405
Cdd:pfam03141 236 EMEDLTKSLCWKLVAKKGDIAIWQKPLNNSCYNKREPGKKPPLCKDSDDPDAAWYVPMEACItplpeVSHEVGGGWPEPW 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607   406 TDRLSSYPTSLRE---KGISEDEFTLDTNFWREQVNQYWELMN--VNKTEVRNVMDTNAFIGGFAAAMNSYPLWVMNVVP 480
Cdd:pfam03141 316 PARLTAVPPRLSSgqiGGVSPESFKADTELWKKRVNKYKRLLKlgIDWGKVRNVMDMNAGFGGFAAALIDLPVWVMNVVP 395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607   481 ATMNDTLSGIYQRGLTGAYHDWCEPFSTYPRTYDLLHADHLFTHYKiygEGCLLEDIMLEMDRIIRPQGFIIIRDEESIV 560
Cdd:pfam03141 396 VDSPNTLPVIYDRGLIGIYHDWCEAFSTYPRTYDLLHADHLFSLYK---KRCNLVDILLEMDRILRPEGFVIIRDSVDVL 472

                         490       500       510
                  ....*....|....*....|....*....|....
gi 15237607   561 SRVRDLAPKFLWEVEAHELQDKYKKTETVLFCRK 594
Cdd:pfam03141 473 DKVKKIAKAMRWEVRMTDTEDGPHVPEKILIAQK 506
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 218-312 3.81e-12

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 62.68  E-value: 3.81e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607   218 LDVGCGVASFAAYLLPLGIKTMSFapkDGHENQIQFALERGIRAMISAIAT--KQMPYPAASFDMVHCSRCrVDWHENDG 295
Cdd:pfam08241   1 LDVGCGTGLLTELLARLGARVTGV---DISPEMLELAREKAPREGLTFVVGdaEDLPFPDNSFDLVLSSEV-LHHVEDPE 76

                          90
                  ....*....|....*..
gi 15237607   296 VLMKEVNRLLRPNGYFV 312
Cdd:pfam08241  77 RALREIARVLKPGGILI 93
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 215-312 1.43e-09

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 56.54  E-value: 1.43e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607 215 EQVLDVGCGVASFAAYLLPLGIKTMSFapkDGHENQIQFALERGIRAMISAIATK----QMPYPAASFDMVHCSRCrVDW 290
Cdd:COG2226  24 ARVLDLGCGTGRLALALAERGARVTGV---DISPEMLELARERAAEAGLNVEFVVgdaeDLPFPDGSFDLVISSFV-LHH 99

                        90       100
                ....*....|....*....|..
gi 15237607 291 HENDGVLMKEVNRLLRPNGYFV 312
Cdd:COG2226 100 LPDPERALAEIARVLKPGGRLV 121
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 217-316 2.81e-09

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 55.41  E-value: 2.81e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607 217 VLDVGCGVASFAAYLLPLGIKTMSFapkDGHENQIQFALERGIRAMISAIAT--KQMPYPAASFDMVHCsrCRVDWH-EN 293
Cdd:COG2227  28 VLDVGCGTGRLALALARRGADVTGV---DISPEALEIARERAAELNVDFVQGdlEDLPLEDGSFDLVIC--SEVLEHlPD 102

                        90       100
                ....*....|....*....|...
gi 15237607 294 DGVLMKEVNRLLRPNGYFVYSAP 316
Cdd:COG2227 103 PAALLRELARLLKPGGLLLLSTP 125
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 217-309 1.35e-08

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 52.57  E-value: 1.35e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607   217 VLDVGCGVASFAAYLLPL------GIktmsfapkDGHENQIQFALERGIRAMISAIATK----QMPYPAASFDMVHCSRC 286
Cdd:pfam13649   1 VLDLGCGTGRLTLALARRggarvtGV--------DLSPEMLERARERAAEAGLNVEFVQgdaeDLPFPDGSFDLVVSSGV 72

                          90       100
                  ....*....|....*....|....
gi 15237607   287 RVDWHENDGV-LMKEVNRLLRPNG 309
Cdd:pfam13649  73 LHHLPDPDLEaALREIARVLKPGG 96
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 216-318 2.39e-05

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 45.68  E-value: 2.39e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607 216 QVLDVGCGVASFAAYLLPLGIKTMSFApkDGHENQIQFALERGIRAMISAI------ATKQMPYPAASFDMVHCSRCrvd 289
Cdd:COG0500  29 RVLDLGCGTGRNLLALAARFGGRVIGI--DLSPEAIALARARAAKAGLGNVeflvadLAELDPLPAESFDLVVAFGV--- 103

                        90       100       110
                ....*....|....*....|....*....|...
gi 15237607 290 WH----ENDGVLMKEVNRLLRPNGYFVYSAPPA 318
Cdd:COG0500 104 LHhlppEEREALLRELARALKPGGVLLLSASDA 136
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
209-318 2.93e-05

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 44.99  E-value: 2.93e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607 209 LLSAGVEQVLDVGCGVASFAAYLLPLGIKTMSFapkDGHENQIQFALERGIRAMISAIATKQMPYPAASFDMVHCSrcrv 288
Cdd:COG4976  42 LPPGPFGRVLDLGCGTGLLGEALRPRGYRLTGV---DLSEEMLAKAREKGVYDRLLVADLADLAEPDGRFDLIVAA---- 114

                        90       100       110
                ....*....|....*....|....*....|....*....
gi 15237607 289 dwhendGVL---------MKEVNRLLRPNGYFVYSAPPA 318
Cdd:COG4976 115 ------DVLtylgdlaavFAGVARALKPGGLFIFSVEDA 147
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 217-312 7.40e-05

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 43.17  E-value: 7.40e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607   217 VLDVGCG---VASFAAYLLPLGIKTMSFapkDGHENQIQFALER-------GIRAMISAIATKQMPYPAASFDMVHCsRC 286
Cdd:pfam13847   7 VLDLGCGtghLSFELAEELGPNAEVVGI---DISEEAIEKARENaqklgfdNVEFEQGDIEELPELLEDDKFDVVIS-NC 82

                          90       100
                  ....*....|....*....|....*..
gi 15237607   287 RVDwHENDGVL-MKEVNRLLRPNGYFV 312
Cdd:pfam13847  83 VLN-HIPDPDKvLQEILRVLKPGGRLI 108
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 210-316 1.68e-04

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 42.22  E-value: 1.68e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607 210 LSAGvEQVLDVGCGVASFAAYLLP------LGIktmsfapkDGHENQIQFALERGIRAMISA-IATKQMPY----PAASF 278
Cdd:COG2230  49 LKPG-MRVLDIGCGWGGLALYLARrygvrvTGV--------TLSPEQLEYARERAAEAGLADrVEVRLADYrdlpADGQF 119

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*
gi 15237607 279 DMV-------HCSrcrvdwHENDGVLMKEVNRLLRPNGYFVYSAP 316
Cdd:COG2230 120 DAIvsigmfeHVG------PENYPAYFAKVARLLKPGGRLLLHTP 158
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
215-312 3.13e-04

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 40.19  E-value: 3.13e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607 215 EQVLDVGCGVASFAAYLLP-------LGIktmsfapkDGHENQIQFALER--GIRAMISAIATKQmpyPAASFDMVHCSR 285
Cdd:COG4106   3 RRVLDLGCGTGRLTALLAErfpgarvTGV--------DLSPEMLARARARlpNVRFVVADLRDLD---PPEPFDLVVSNA 71

                        90       100
                ....*....|....*....|....*..
gi 15237607 286 CrVDWHENDGVLMKEVNRLLRPNGYFV 312
Cdd:COG4106  72 A-LHWLPDHAALLARLAAALAPGGVLA 97
Methyltransf_23 pfam13489
Methyltransferase domain; This family appears to be a methyltransferase domain.
 217-314 5.93e-04

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 404385 [Multi-domain]  Cd Length: 162  Bit Score: 40.87  E-value: 5.93e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607   217 VLDVGCGVASFAAYLLPLGIKTMSFAPKDGhenqiqfALERGIRAMISAIATKQMP-YPAASFDMVHCSR--CRV-DWHE 292
Cdd:pfam13489  26 VLDFGCGTGIFLRLLRAQGFSVTGVDPSPI-------AIERALLNVRFDQFDEQEAaVPAGKFDVIVAREvlEHVpDPPA 98

                          90       100
                  ....*....|....*....|..
gi 15237607   293 ndgvLMKEVNRLLRPNGYFVYS 314
Cdd:pfam13489  99 ----LLRQIAALLKPGGLLLLS 116
PRK08317 PRK08317
hypothetical protein; Provisional
 215-316 1.93e-03

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 40.31  E-value: 1.93e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607  215 EQVLDVGCG----VASFAAYLLP----LGIktmsfapkDGHENQIQFALER-----GIRAMISAIATkQMPYPAASFDMV 281
Cdd:PRK08317  21 DRVLDVGCGpgndARELARRVGPegrvVGI--------DRSEAMLALAKERaaglgPNVEFVRGDAD-GLPFPDGSFDAV 91

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 15237607  282 hCSrCRVDWH-ENDGVLMKEVNRLLRPNGYFVYSAP 316
Cdd:PRK08317  92 -RS-DRVLQHlEDPARALAEIARVLRPGGRVVVLDT 125
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 217-314 3.41e-03

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 37.41  E-value: 3.41e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237607 217 VLDVGCGVASFAAYLLPLGIK--TMSfapkDGHENQIQFALERGIRAMISAI------ATKQMPYPAASFDMVHCSRCRV 288
Cdd:cd02440   2 VLDLGCGTGALALALASGPGArvTGV----DISPVALELARKAAAALLADNVevlkgdAEELPPEADESFDVIISDPPLH 77

                        90       100
                ....*....|....*....|....*.
gi 15237607 289 DWHENDGVLMKEVNRLLRPNGYFVYS 314
Cdd:cd02440  78 HLVEDLARFLEEARRLLKPGGVLVLT 103
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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