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Conserved domains on  [gi|15242650|ref|NP_195936|]
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DnaJ P58IPK-like protein [Arabidopsis thaliana]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11929115)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  30708253|10517866
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10767 super family cl35946
chaperone protein DnaJ; Provisional
 365-434 1.59e-30

chaperone protein DnaJ; Provisional


The actual alignment was detected with superfamily member PRK10767:

Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 121.79  E-value: 1.59e-30
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650  365 MSKRkDWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNrEEAENKFREIAAAYEILGDDDKRARFDR 434
Cdd:PRK10767   1 MAKR-DYYEVLGVSRNASEDEIKKAYRKLAMKYHPDRNPGD-KEAEEKFKEIKEAYEVLSDPQKRAAYDQ 68
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 13-235 2.27e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 66.17  E-value: 2.27e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650  13 LAWRGMAYTLLLLNFVFACQLLLLQPLVSALDGQSVDAAELFERASQSIKVKRYSDALDDLNAAIEADPALSEAYFKRAS 92
Cdd:COG3914  41 LGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGN 120

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650  93 VLRHFCRYEDSENSYQKYLEFKSGDSNAEKELSQLHQAKSALETASTLYEskdiaKALEFvdkvvlvfspacskakllkv 172
Cdd:COG3914 121 LLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALR-----RALEL-------------------- 175

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15242650 173 kllmvskdysgaisetgyilkeDENNLEALLLRGRAYYYLADHDIAQRHYQKGLRLDPEHSEL 235
Cdd:COG3914 176 ----------------------DPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADA 216
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
192-440 3.92e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 63.10  E-value: 3.92e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 192 LKEDENNLEALLLRGRAYYYLADHDIAQRHYQKGLRLDPEHSElkkAYFGLkkllkktksAEDNANKGKLRVSAEEYKEA 271
Cdd:COG0457   1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAE---ALYNL---------GLAYLRLGRYEEALADYEQA 68

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 272 IALDPEHTanNVHLYLGLCKvsVRLGRGKDGLNSCNEALNIDAELIEALHQRGEAKLLLEDWEGAVEDLKQAAQNSQDM- 350
Cdd:COG0457  69 LELDPDDA--EALNNLGLAL--QALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDa 144

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 351 -------EIHESLGKAEKALKMSKRKDWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNREEAENKFREIAAAYEIL 423
Cdd:COG0457 145 dalynlgIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLL 224

                       250
                ....*....|....*..
gi 15242650 424 GDDDKRARFDRGEDLED 440
Cdd:COG0457 225 LALALLLALRLAALALY 241
 
Name Accession Description Interval E-value
PRK10767 PRK10767
chaperone protein DnaJ; Provisional
 365-434 1.59e-30

chaperone protein DnaJ; Provisional


Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 121.79  E-value: 1.59e-30
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650  365 MSKRkDWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNrEEAENKFREIAAAYEILGDDDKRARFDR 434
Cdd:PRK10767   1 MAKR-DYYEVLGVSRNASEDEIKKAYRKLAMKYHPDRNPGD-KEAEEKFKEIKEAYEVLSDPQKRAAYDQ 68
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 370-433 7.50e-28

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 105.25  E-value: 7.50e-28
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15242650   370 DWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNrEEAENKFREIAAAYEILGDDDKRARFD 433
Cdd:pfam00226   1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNPGD-PEAEEKFKEINEAYEVLSDPEKRAIYD 63
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 370-434 4.05e-27

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 111.92  E-value: 4.05e-27
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15242650   370 DWYKILGISRTASISEIKKAYKKLALQWHPDKNvgNREEAENKFREIAAAYEILGDDDKRARFDR 434
Cdd:TIGR02349   1 DYYEILGVSKDASEEEIKKAYRKLAKKYHPDRN--KDKEAEEKFKEINEAYEVLSDPEKRAQYDQ 63
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 370-435 2.60e-24

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 98.24  E-value: 2.60e-24
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15242650 370 DWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNrEEAENKFREIAAAYEILGDDDKRARFDRG 435
Cdd:COG0484   1 DYYEILGVSRDASAEEIKKAYRKLAKKYHPDRNPGD-PEAEEKFKEINEAYEVLSDPEKRAAYDRF 65
DnaJ smart00271
DnaJ molecular chaperone homology domain;
369-428 4.14e-24

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 94.99  E-value: 4.14e-24
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650    369 KDWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNREEAENKFREIAAAYEILGDDDK 428
Cdd:smart00271   1 TDYYEILGVPRDASLDEIKKAYRKLALKYHPDKNPGDKEEAEEKFKEINEAYEVLSDPEK 60
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 370-425 2.36e-21

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 87.22  E-value: 2.36e-21
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 15242650 370 DWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNrEEAENKFREIAAAYEILGD 425
Cdd:cd06257   1 DYYDILGVPPDASDEEIKKAYRKLALKYHPDKNPDD-PEAEEKFKEINEAYEVLSD 55
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 13-235 2.27e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 66.17  E-value: 2.27e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650  13 LAWRGMAYTLLLLNFVFACQLLLLQPLVSALDGQSVDAAELFERASQSIKVKRYSDALDDLNAAIEADPALSEAYFKRAS 92
Cdd:COG3914  41 LGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGN 120

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650  93 VLRHFCRYEDSENSYQKYLEFKSGDSNAEKELSQLHQAKSALETASTLYEskdiaKALEFvdkvvlvfspacskakllkv 172
Cdd:COG3914 121 LLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALR-----RALEL-------------------- 175

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15242650 173 kllmvskdysgaisetgyilkeDENNLEALLLRGRAYYYLADHDIAQRHYQKGLRLDPEHSEL 235
Cdd:COG3914 176 ----------------------DPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADA 216
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
192-440 3.92e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 63.10  E-value: 3.92e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 192 LKEDENNLEALLLRGRAYYYLADHDIAQRHYQKGLRLDPEHSElkkAYFGLkkllkktksAEDNANKGKLRVSAEEYKEA 271
Cdd:COG0457   1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAE---ALYNL---------GLAYLRLGRYEEALADYEQA 68

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 272 IALDPEHTanNVHLYLGLCKvsVRLGRGKDGLNSCNEALNIDAELIEALHQRGEAKLLLEDWEGAVEDLKQAAQNSQDM- 350
Cdd:COG0457  69 LELDPDDA--EALNNLGLAL--QALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDa 144

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 351 -------EIHESLGKAEKALKMSKRKDWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNREEAENKFREIAAAYEIL 423
Cdd:COG0457 145 dalynlgIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLL 224

                       250
                ....*....|....*..
gi 15242650 424 GDDDKRARFDRGEDLED 440
Cdd:COG0457 225 LALALLLALRLAALALY 241
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 39-147 1.19e-05

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 47.47  E-value: 1.19e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650   39 LVSALDGQSVDA----AELF-ERASQSIKVKRYSDALDDLNAAIEADPALSEAYFKRASVLRHFCRYEDSENSYQKYLEF 113
Cdd:PLN03088  20 LAVDLYTQAIDLdpnnAELYaDRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACMKLEEYQTAKAALEKGASL 99

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 15242650  114 KSGDSN-----------AEKELSQLHQAKSALETASTLYESKDIA 147
Cdd:PLN03088 100 APGDSRftklikecdekIAEEEKDLVQPVPSDLPSSVTAPPVEEA 144
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 34-152 7.62e-05

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 45.36  E-value: 7.62e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650    34 LLLQPLVSALDGQSVDAAELFERASQSIKVKRYS------------------DALDDLNAAIEADPALSEAYFKRASVLR 95
Cdd:TIGR00990 297 LGLKSPESKADESYEEAARAFEKALDLGKLGEKEaialnlrgtfkclkgkhlEALADLSKSIELDPRVTQSYIKRASMNL 376

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 15242650    96 HFCRYEDSENSYQKYLEFKSGDSNAEKELSQLHQAKSALETAstlyeSKDIAKALEF 152
Cdd:TIGR00990 377 ELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQA-----GKDYQKSIDL 428
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 180-345 8.52e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.99  E-value: 8.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650   180 DYSGAISETGYILKEDENNLEALLLRGRAYYYLADHDIAQRHYQKGLRLDPEHS----ELKKAYFGL--------KKLLK 247
Cdd:TIGR02917  37 KYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALSLGYPKNqvlpLLARAYLLQgkfqqvldELPGK 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650   248 KTKSAEDNA-----------NKGKLRVSAEEYKEAIALDPEhtanNVHLYLGLCKVSVRLGRGKDGLNSCNEALNIDAEL 316
Cdd:TIGR02917 117 TLLDDEGAAellalrglaylGLGQLELAQKSYEQALAIDPR----SLYAKLGLAQLALAENRFDEARALIDEVLTADPGN 192

                         170       180
                  ....*....|....*....|....*....
gi 15242650   317 IEALHQRGEAKLLLEDWEGAVEDLKQAAQ 345
Cdd:TIGR02917 193 VDALLLKGDLLLSLGNIELALAAYRKAIA 221
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 200-232 8.40e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 33.96  E-value: 8.40e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 15242650    200 EALLLRGRAYYYLADHDIAQRHYQKGLRLDPEH 232
Cdd:smart00028   2 EALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
 
Name Accession Description Interval E-value
PRK10767 PRK10767
chaperone protein DnaJ; Provisional
 365-434 1.59e-30

chaperone protein DnaJ; Provisional


Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 121.79  E-value: 1.59e-30
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650  365 MSKRkDWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNrEEAENKFREIAAAYEILGDDDKRARFDR 434
Cdd:PRK10767   1 MAKR-DYYEVLGVSRNASEDEIKKAYRKLAMKYHPDRNPGD-KEAEEKFKEIKEAYEVLSDPQKRAAYDQ 68
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 370-433 7.50e-28

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 105.25  E-value: 7.50e-28
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15242650   370 DWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNrEEAENKFREIAAAYEILGDDDKRARFD 433
Cdd:pfam00226   1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNPGD-PEAEEKFKEINEAYEVLSDPEKRAIYD 63
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 370-434 4.05e-27

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 111.92  E-value: 4.05e-27
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15242650   370 DWYKILGISRTASISEIKKAYKKLALQWHPDKNvgNREEAENKFREIAAAYEILGDDDKRARFDR 434
Cdd:TIGR02349   1 DYYEILGVSKDASEEEIKKAYRKLAKKYHPDRN--KDKEAEEKFKEINEAYEVLSDPEKRAQYDQ 63
PRK14281 PRK14281
chaperone protein DnaJ; Provisional
 368-434 1.65e-25

chaperone protein DnaJ; Provisional


Pssm-ID: 237657 [Multi-domain]  Cd Length: 397  Bit Score: 107.97  E-value: 1.65e-25
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15242650  368 RKDWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNReEAENKFREIAAAYEILGDDDKRARFDR 434
Cdd:PRK14281   2 KRDYYEVLGVSRSADKDEIKKAYRKLALKYHPDKNPDNK-EAEEHFKEVNEAYEVLSNDDKRRRYDQ 67
PRK14301 PRK14301
chaperone protein DnaJ; Provisional
 365-434 2.52e-25

chaperone protein DnaJ; Provisional


Pssm-ID: 237668 [Multi-domain]  Cd Length: 373  Bit Score: 107.14  E-value: 2.52e-25
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650  365 MSKRkDWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNrEEAENKFREIAAAYEILGDDDKRARFDR 434
Cdd:PRK14301   1 MSQR-DYYEVLGVSRDASEDEIKKAYRKLALQYHPDRNPDN-PEAEQKFKEAAEAYEVLRDAEKRARYDR 68
PRK14282 PRK14282
chaperone protein DnaJ; Provisional
 368-434 3.16e-25

chaperone protein DnaJ; Provisional


Pssm-ID: 184603 [Multi-domain]  Cd Length: 369  Bit Score: 106.80  E-value: 3.16e-25
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15242650  368 RKDWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNREEAENKFREIAAAYEILGDDDKRARFDR 434
Cdd:PRK14282   3 KKDYYEILGVSRNATQEEIKRAYKRLVKEWHPDRHPENRKEAEQKFKEIQEAYEVLSDPQKRAMYDR 69
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 370-435 2.60e-24

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 98.24  E-value: 2.60e-24
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15242650 370 DWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNrEEAENKFREIAAAYEILGDDDKRARFDRG 435
Cdd:COG0484   1 DYYEILGVSRDASAEEIKKAYRKLAKKYHPDRNPGD-PEAEEKFKEINEAYEVLSDPEKRAAYDRF 65
PRK14298 PRK14298
chaperone protein DnaJ; Provisional
 365-434 3.67e-24

chaperone protein DnaJ; Provisional


Pssm-ID: 184612 [Multi-domain]  Cd Length: 377  Bit Score: 103.78  E-value: 3.67e-24
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650  365 MSKRKDWYKILGISRTASISEIKKAYKKLALQWHPDKNvgNREEAENKFREIAAAYEILGDDDKRARFDR 434
Cdd:PRK14298   1 MATTRDYYEILGLSKDASVEDIKKAYRKLAMKYHPDKN--KEPDAEEKFKEISEAYAVLSDAEKRAQYDR 68
DnaJ smart00271
DnaJ molecular chaperone homology domain;
369-428 4.14e-24

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 94.99  E-value: 4.14e-24
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650    369 KDWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNREEAENKFREIAAAYEILGDDDK 428
Cdd:smart00271   1 TDYYEILGVPRDASLDEIKKAYRKLALKYHPDKNPGDKEEAEEKFKEINEAYEVLSDPEK 60
PRK14289 PRK14289
molecular chaperone DnaJ;
365-434 6.45e-24

molecular chaperone DnaJ;


Pssm-ID: 237660 [Multi-domain]  Cd Length: 386  Bit Score: 102.99  E-value: 6.45e-24
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650  365 MSKRKDWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNReEAENKFREIAAAYEILGDDDKRARFDR 434
Cdd:PRK14289   1 MAEKRDYYEVLGVSKTATVDEIKKAYRKKAIQYHPDKNPGDK-EAEEKFKEAAEAYDVLSDPDKRSRYDQ 69
PRK14280 PRK14280
molecular chaperone DnaJ;
365-434 2.87e-23

molecular chaperone DnaJ;


Pssm-ID: 237656 [Multi-domain]  Cd Length: 376  Bit Score: 100.95  E-value: 2.87e-23
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650  365 MSKRkDWYKILGISRTASISEIKKAYKKLALQWHPDKNvgNREEAENKFREIAAAYEILGDDDKRARFDR 434
Cdd:PRK14280   1 MAKR-DYYEVLGVSKSASKDEIKKAYRKLSKKYHPDIN--KEEGADEKFKEISEAYEVLSDDQKRAQYDQ 67
PRK14277 PRK14277
chaperone protein DnaJ; Provisional
 365-434 6.29e-23

chaperone protein DnaJ; Provisional


Pssm-ID: 184599 [Multi-domain]  Cd Length: 386  Bit Score: 100.26  E-value: 6.29e-23
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650  365 MSKRKDWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNReEAENKFREIAAAYEILGDDDKRARFDR 434
Cdd:PRK14277   1 MAAKKDYYEILGVDRNATEEEIKKAYRRLAKKYHPDLNPGDK-EAEQKFKEINEAYEILSDPQKRAQYDQ 69
PRK14294 PRK14294
chaperone protein DnaJ; Provisional
 366-434 5.03e-22

chaperone protein DnaJ; Provisional


Pssm-ID: 237664 [Multi-domain]  Cd Length: 366  Bit Score: 97.14  E-value: 5.03e-22
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15242650  366 SKRKDWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNReEAENKFREIAAAYEILGDDDKRARFDR 434
Cdd:PRK14294   1 MVKRDYYEILGVTRDASEEEIKKSYRKLAMKYHPDRNPGDK-EAEELFKEAAEAYEVLSDPKKRGIYDQ 68
SEC63 COG5407
Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular ...
 370-431 5.14e-22

Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 444165 [Multi-domain]  Cd Length: 61  Bit Score: 88.90  E-value: 5.14e-22
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15242650 370 DWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNReEAENKFREIAAAYEILGDDDKRAR 431
Cdd:COG5407   1 DPYEVLGVAKTASADEIKKAYRKLAKKYHPDRNKGDP-KAEERFKEINEAYELLSDAEKRAR 61
PRK14295 PRK14295
molecular chaperone DnaJ;
364-438 8.63e-22

molecular chaperone DnaJ;


Pssm-ID: 237665 [Multi-domain]  Cd Length: 389  Bit Score: 96.84  E-value: 8.63e-22
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15242650  364 KMSKRKDWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNrEEAENKFREIAAAYEILGDDDKRARFDRGEDL 438
Cdd:PRK14295   4 KDYIEKDYYKVLGVPKDATEAEIKKAYRKLAREYHPDANKGD-AKAEERFKEISEAYDVLSDEKKRKEYDEARSL 77
PRK14283 PRK14283
chaperone protein DnaJ; Provisional
 365-434 9.86e-22

chaperone protein DnaJ; Provisional


Pssm-ID: 184604 [Multi-domain]  Cd Length: 378  Bit Score: 96.82  E-value: 9.86e-22
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650  365 MSKRKDWYKILGISRTASISEIKKAYKKLALQWHPDknVGNREEAENKFREIAAAYEILGDDDKRARFDR 434
Cdd:PRK14283   1 MAEKRDYYEVLGVDRNADKKEIKKAYRKLARKYHPD--VSEEEGAEEKFKEISEAYAVLSDDEKRQRYDQ 68
PRK14285 PRK14285
chaperone protein DnaJ; Provisional
 368-434 1.08e-21

chaperone protein DnaJ; Provisional


Pssm-ID: 172773 [Multi-domain]  Cd Length: 365  Bit Score: 96.21  E-value: 1.08e-21
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15242650  368 RKDWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNrEEAENKFREIAAAYEILGDDDKRARFDR 434
Cdd:PRK14285   2 KRDYYEILGLSKGASKDEIKKAYRKIAIKYHPDKNKGN-KEAESIFKEATEAYEVLIDDNKRAQYDR 67
PRK14284 PRK14284
chaperone protein DnaJ; Provisional
 370-437 1.11e-21

chaperone protein DnaJ; Provisional


Pssm-ID: 237658 [Multi-domain]  Cd Length: 391  Bit Score: 96.84  E-value: 1.11e-21
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15242650  370 DWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNrEEAENKFREIAAAYEILGDDDKRARFDR-GED 437
Cdd:PRK14284   2 DYYTILGVSKTASPEEIKKAYRKLAVKYHPDKNPGD-AEAEKRFKEVSEAYEVLSDAQKRESYDRyGKD 69
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 370-425 2.36e-21

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 87.22  E-value: 2.36e-21
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 15242650 370 DWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNrEEAENKFREIAAAYEILGD 425
Cdd:cd06257   1 DYYDILGVPPDASDEEIKKAYRKLALKYHPDKNPDD-PEAEEKFKEINEAYEVLSD 55
PRK14290 PRK14290
chaperone protein DnaJ; Provisional
 369-434 2.40e-21

chaperone protein DnaJ; Provisional


Pssm-ID: 172778 [Multi-domain]  Cd Length: 365  Bit Score: 95.38  E-value: 2.40e-21
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15242650  369 KDWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNREEAENKFREIAAAYEILGDDDKRARFDR 434
Cdd:PRK14290   3 KDYYKILGVDRNASQEDIKKAFRELAKKWHPDLHPGNKAEAEEKFKEISEAYEVLSDPQKRRQYDQ 68
PRK14297 PRK14297
molecular chaperone DnaJ;
365-434 2.78e-21

molecular chaperone DnaJ;


Pssm-ID: 184611 [Multi-domain]  Cd Length: 380  Bit Score: 95.24  E-value: 2.78e-21
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650  365 MSKrKDWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNReEAENKFREIAAAYEILGDDDKRARFDR 434
Cdd:PRK14297   1 MAS-KDYYEVLGLEKGASDDEIKKAFRKLAIKYHPDKNKGNK-EAEEKFKEINEAYQVLSDPQKKAQYDQ 68
PRK14293 PRK14293
molecular chaperone DnaJ;
370-436 2.59e-20

molecular chaperone DnaJ;


Pssm-ID: 237663 [Multi-domain]  Cd Length: 374  Bit Score: 92.36  E-value: 2.59e-20
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15242650  370 DWYKILGISRTASISEIKKAYKKLALQWHPDKnvgNREE-AENKFREIAAAYEILGDDDKRARFDR-GE 436
Cdd:PRK14293   4 DYYEILGVSRDADKDELKRAYRRLARKYHPDV---NKEPgAEDRFKEINRAYEVLSDPETRARYDQfGE 69
CbpA COG2214
Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];
365-435 3.36e-20

Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];


Pssm-ID: 441816 [Multi-domain]  Cd Length: 91  Bit Score: 85.15  E-value: 3.36e-20
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15242650 365 MSKRKDWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNREEAENKFREIAAAYEILGDDDKRARFDRG 435
Cdd:COG2214   1 MPDLKDHYAVLGVPPDASLEEIRQAYRRLAKLLHPDRGGELKALAEELFQRLNEAYEVLSDPERRAEYDRE 71
PRK14278 PRK14278
chaperone protein DnaJ; Provisional
 369-437 1.70e-19

chaperone protein DnaJ; Provisional


Pssm-ID: 237654 [Multi-domain]  Cd Length: 378  Bit Score: 90.11  E-value: 1.70e-19
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15242650  369 KDWYKILGISRTASISEIKKAYKKLALQWHPDKNVGnrEEAENKFREIAAAYEILGDDDKRARFDRGED 437
Cdd:PRK14278   3 RDYYGLLGVSRNASDAEIKRAYRKLARELHPDVNPD--EEAQEKFKEISVAYEVLSDPEKRRIVDLGGD 69
PRK14291 PRK14291
chaperone protein DnaJ; Provisional
 368-433 5.97e-19

chaperone protein DnaJ; Provisional


Pssm-ID: 237661 [Multi-domain]  Cd Length: 382  Bit Score: 88.29  E-value: 5.97e-19
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15242650  368 RKDWYKILGISRTASISEIKKAYKKLALQWHPDKNvgNREEAENKFREIAAAYEILGDDDKRARFD 433
Cdd:PRK14291   2 KKDYYEILGVSRNATQEEIKKAYRRLARKYHPDFN--KNPEAEEKFKEINEAYQVLSDPEKRKLYD 65
PRK14279 PRK14279
molecular chaperone DnaJ;
365-433 1.76e-18

molecular chaperone DnaJ;


Pssm-ID: 237655 [Multi-domain]  Cd Length: 392  Bit Score: 87.10  E-value: 1.76e-18
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15242650  365 MSKR----KDWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNReEAENKFREIAAAYEILGDDDKRARFD 433
Cdd:PRK14279   1 MAQRewveKDFYKELGVSSDASAEEIKKAYRKLARELHPDANPGDP-AAEERFKAVSEAHDVLSDPAKRKEYD 72
PRK14286 PRK14286
chaperone protein DnaJ; Provisional
 365-434 2.59e-18

chaperone protein DnaJ; Provisional


Pssm-ID: 172774 [Multi-domain]  Cd Length: 372  Bit Score: 86.58  E-value: 2.59e-18
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650  365 MSKRkDWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNReEAENKFREIAAAYEILGDDDKRARFDR 434
Cdd:PRK14286   1 MSER-SYYDILGVSKSANDEEIKSAYRKLAIKYHPDKNKGNK-ESEEKFKEATEAYEILRDPKKRQAYDQ 68
PRK14299 PRK14299
chaperone protein DnaJ; Provisional
 369-434 2.60e-18

chaperone protein DnaJ; Provisional


Pssm-ID: 237667 [Multi-domain]  Cd Length: 291  Bit Score: 84.99  E-value: 2.60e-18
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15242650  369 KDWYKILGISRTASISEIKKAYKKLALQWHPDknVGNREEAENKFREIAAAYEILGDDDKRARFDR 434
Cdd:PRK14299   4 KDYYAILGVPKNASQDEIKKAFKKLARKYHPD--VNKSPGAEEKFKEINEAYTVLSDPEKRRIYDT 67
PRK14300 PRK14300
chaperone protein DnaJ; Provisional
 369-437 3.01e-18

chaperone protein DnaJ; Provisional


Pssm-ID: 172788 [Multi-domain]  Cd Length: 372  Bit Score: 86.22  E-value: 3.01e-18
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650  369 KDWYKILGISRTASISEIKKAYKKLALQWHPDKNvgNREEAENKFREIAAAYEILGDDDKRARFDR-GED 437
Cdd:PRK14300   3 QDYYQILGVSKTASQADLKKAYLKLAKQYHPDTT--DAKDAEKKFKEINAAYDVLKDEQKRAAYDRfGHD 70
PRK14276 PRK14276
chaperone protein DnaJ; Provisional
 369-433 6.96e-18

chaperone protein DnaJ; Provisional


Pssm-ID: 237653 [Multi-domain]  Cd Length: 380  Bit Score: 85.14  E-value: 6.96e-18
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15242650  369 KDWYKILGISRTASISEIKKAYKKLALQWHPDKNvgNREEAENKFREIAAAYEILGDDDKRARFD 433
Cdd:PRK14276   4 TEYYDRLGVSKDASQDEIKKAYRKLSKKYHPDIN--KEPGAEEKYKEVQEAYETLSDPQKRAAYD 66
PRK14292 PRK14292
chaperone protein DnaJ; Provisional
 370-434 1.18e-17

chaperone protein DnaJ; Provisional


Pssm-ID: 237662 [Multi-domain]  Cd Length: 371  Bit Score: 84.56  E-value: 1.18e-17
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15242650  370 DWYKILGISRTASISEIKKAYKKLALQWHPDKNvgNREEAENKFREIAAAYEILGDDDKRARFDR 434
Cdd:PRK14292   3 DYYELLGVSRTASADEIKSAYRKLALKYHPDRN--KEKGAAEKFAQINEAYAVLSDAEKRAHYDR 65
PRK14287 PRK14287
chaperone protein DnaJ; Provisional
 365-434 3.08e-17

chaperone protein DnaJ; Provisional


Pssm-ID: 237659 [Multi-domain]  Cd Length: 371  Bit Score: 83.13  E-value: 3.08e-17
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650  365 MSKRkDWYKILGISRTASISEIKKAYKKLALQWHPDknVGNREEAENKFREIAAAYEILGDDDKRARFDR 434
Cdd:PRK14287   1 MSKR-DYYEVLGVDRNASVDEVKKAYRKLARKYHPD--VNKAPDAEDKFKEVKEAYDTLSDPQKKAHYDQ 67
PRK10266 PRK10266
curved DNA-binding protein;
369-434 2.15e-16

curved DNA-binding protein;


Pssm-ID: 182347 [Multi-domain]  Cd Length: 306  Bit Score: 79.87  E-value: 2.15e-16
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15242650  369 KDWYKILGISRTASISEIKKAYKKLALQWHPDknVGNREEAENKFREIAAAYEILGDDDKRARFDR 434
Cdd:PRK10266   4 KDYYAIMGVKPTDDLKTIKTAYRRLARKYHPD--VSKEPDAEARFKEVAEAWEVLSDEQRRAEYDQ 67
PTZ00037 PTZ00037
DnaJ_C chaperone protein; Provisional
 369-437 6.40e-16

DnaJ_C chaperone protein; Provisional


Pssm-ID: 240236 [Multi-domain]  Cd Length: 421  Bit Score: 79.48  E-value: 6.40e-16
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650  369 KDWYKILGISRTASISEIKKAYKKLALQWHPDKNvGNREeaenKFREIAAAYEILGDDDKRARFDR-GED 437
Cdd:PTZ00037  28 EKLYEVLNLSKDCTTSEIKKAYRKLAIKHHPDKG-GDPE----KFKEISRAYEVLSDPEKRKIYDEyGEE 92
PRK14296 PRK14296
chaperone protein DnaJ; Provisional
 367-434 3.04e-15

chaperone protein DnaJ; Provisional


Pssm-ID: 237666 [Multi-domain]  Cd Length: 372  Bit Score: 77.29  E-value: 3.04e-15
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15242650  367 KRKDWYKILGISRTASISEIKKAYKKLALQWHPDKNvgNREEAENKFREIAAAYEILGDDDKRARFDR 434
Cdd:PRK14296   2 KKKDYYEVLGVSKTASEQEIRQAYRKLAKQYHPDLN--KSPDAHDKMVEINEAADVLLDKDKRKQYDQ 67
PRK14288 PRK14288
molecular chaperone DnaJ;
371-434 1.54e-11

molecular chaperone DnaJ;


Pssm-ID: 172776 [Multi-domain]  Cd Length: 369  Bit Score: 65.87  E-value: 1.54e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15242650  371 WYKILGISRTASISEIKKAYKKLALQWHPDKNVGNReEAENKFREIAAAYEILGDDDKRARFDR 434
Cdd:PRK14288   5 YYEILEVEKHSNQETIKKSYRKLALKYHPDRNAGDK-EAEEKFKLINEAYGVLSDEKKRALYDR 67
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 13-235 2.27e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 66.17  E-value: 2.27e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650  13 LAWRGMAYTLLLLNFVFACQLLLLQPLVSALDGQSVDAAELFERASQSIKVKRYSDALDDLNAAIEADPALSEAYFKRAS 92
Cdd:COG3914  41 LGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGN 120

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650  93 VLRHFCRYEDSENSYQKYLEFKSGDSNAEKELSQLHQAKSALETASTLYEskdiaKALEFvdkvvlvfspacskakllkv 172
Cdd:COG3914 121 LLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALR-----RALEL-------------------- 175

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15242650 173 kllmvskdysgaisetgyilkeDENNLEALLLRGRAYYYLADHDIAQRHYQKGLRLDPEHSEL 235
Cdd:COG3914 176 ----------------------DPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADA 216
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
192-440 3.92e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 63.10  E-value: 3.92e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 192 LKEDENNLEALLLRGRAYYYLADHDIAQRHYQKGLRLDPEHSElkkAYFGLkkllkktksAEDNANKGKLRVSAEEYKEA 271
Cdd:COG0457   1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAE---ALYNL---------GLAYLRLGRYEEALADYEQA 68

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 272 IALDPEHTanNVHLYLGLCKvsVRLGRGKDGLNSCNEALNIDAELIEALHQRGEAKLLLEDWEGAVEDLKQAAQNSQDM- 350
Cdd:COG0457  69 LELDPDDA--EALNNLGLAL--QALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDa 144

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 351 -------EIHESLGKAEKALKMSKRKDWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNREEAENKFREIAAAYEIL 423
Cdd:COG0457 145 dalynlgIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLL 224

                       250
                ....*....|....*..
gi 15242650 424 GDDDKRARFDRGEDLED 440
Cdd:COG0457 225 LALALLLALRLAALALY 241
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 311-434 4.11e-11

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 65.58  E-value: 4.11e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650   311 NIDAELIEALHQRGEAKLLLEDWEGAVEDLKQAAQNSQDMEIHESLgkaekalkmskrkdWYKILGISRTASISEIKKAY 390
Cdd:PTZ00341  529 HVEEPTIAEEHVEEEISTAEEHIEEPASDVQQDSEAAPTIEIPDTL--------------FYDILGVGVNADMKEISERY 594

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 15242650   391 KKLALQWHPDKNVGNreEAENKFREIAAAYEILGDDDKRARFDR 434
Cdd:PTZ00341  595 FKLAENYYPPKRSGN--EGFHKFKKINEAYQILGDIDKKKMYNK 636
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 54-367 1.04e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 62.44  E-value: 1.04e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650  54 FERASQSIKVKRYSDALDDLNAAIEADPALSEAYFKRASVLRHFCRYEDSENSYQKYLEFKSGDSNAEKELSQLHQAKSA 133
Cdd:COG2956  12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGL 91

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 134 LETASTLYESkdiakalefvdkvvlvfspacskakllkvkllmvskdysgaisetgyILKEDENNLEALLLRGRAYYYLA 213
Cdd:COG2956  92 LDRAEELLEK-----------------------------------------------LLELDPDDAEALRLLAEIYEQEG 124

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 214 DHDIAQRHYQKGLRLDPEHSELKKAYfglkkllkktksAEDNANKGKLRVSAEEYKEAIALDPehtaNNVHLYLGLCKVS 293
Cdd:COG2956 125 DWEKAIEVLERLLKLGPENAHAYCEL------------AELYLEQGDYDEAIEALEKALKLDP----DCARALLLLAELY 188

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15242650 294 VRLGRGKDGLNSCNEALNIDAELIEALHQRGEAKLLLEDWEGAVEDLKQAAQNSQDMEIHESLGKAEKALKMSK 367
Cdd:COG2956 189 LEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERKEGLE 262
DjlA COG1076
DnaJ domain-containing protein [Posttranslational modification, protein turnover, chaperones];
370-423 2.13e-10

DnaJ domain-containing protein [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440694 [Multi-domain]  Cd Length: 75  Bit Score: 56.73  E-value: 2.13e-10
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 15242650 370 DWYKILGISRTASISEIKKAYKKLALQWHPDKNVGN-----REEAENKFREIAAAYEIL 423
Cdd:COG1076   5 DAFELLGLPPDADDAELKRAYRKLQREHHPDRLAAGlpeeeQRLALQKAAAINEAYETL 63
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
179-363 1.35e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 58.48  E-value: 1.35e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 179 KDYSGAISETGYILKEDENNLEALLLRGRAYYYLADHDIAQRHYQKGLRLDPEHSElkkAYFGLkkllkktksAEDNANK 258
Cdd:COG0457  22 GRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAE---ALNNL---------GLALQAL 89

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 259 GKLRVSAEEYKEAIALDPehtaNNVHLYLGLCKVSVRLGRGKDGLNSCNEALNIDAELIEALHQRGEAKLLLEDWEGAVE 338
Cdd:COG0457  90 GRYEEALEDYDKALELDP----DDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALE 165

                       170       180
                ....*....|....*....|....*
gi 15242650 339 DLKQAAQNSQDMEIHESLGKAEKAL 363
Cdd:COG0457 166 LLEKLEAAALAALLAAALGEAALAL 190
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 180-349 2.75e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 59.62  E-value: 2.75e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 180 DYSGAISETGYILKEDENNLEALLLRGRAYYYLADHDIAQRHYQKGLRLDPEHSELKKAYfglkkllkktksAEDNANKG 259
Cdd:COG3914  93 RYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNL------------GEALRRLG 160

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 260 KLRVSAEEYKEAIALDPehtaNNVHLYLGLCKVSVRLGRGKDGLNSCNEALNIDAELIEALHQRGEAKLLLEDWEGAVED 339
Cdd:COG3914 161 RLEEAIAALRRALELDP----DNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRF 236

                       170
                ....*....|
gi 15242650 340 LKQAAQNSQD 349
Cdd:COG3914 237 EELLAALARG 246
djlA PRK09430
co-chaperone DjlA;
369-431 6.23e-09

co-chaperone DjlA;


Pssm-ID: 236512 [Multi-domain]  Cd Length: 267  Bit Score: 56.74  E-value: 6.23e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15242650  369 KDWYKILGISRTASISEIKKAYKKLALQWHPDKNV--GNREE----AENKFREIAAAYEILgdddKRAR 431
Cdd:PRK09430 200 EDAYKVLGVSESDDDQEIKRAYRKLMSEHHPDKLVakGLPPEmmemAKEKAQEIQAAYELI----KKQK 264
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 191-345 1.07e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 57.70  E-value: 1.07e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 191 ILKEDENNLEALLLRGRAYYYLADHDIAQRHYQKGLRLDPEHSElkkAYFGLKKLLKKtksaednanKGKLRVSAEEYKE 270
Cdd:COG3914  70 AAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAE---ALFNLGNLLLA---------LGRLEEALAALRR 137

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15242650 271 AIALDPEHtannVHLYLGLCKVSVRLGRGKDGLNSCNEALNIDAELIEALHQRGEAKLLLEDWEGAVEDLKQAAQ 345
Cdd:COG3914 138 ALALNPDF----AEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALE 208
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
49-277 1.19e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 52.70  E-value: 1.19e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650  49 DAAELFERASQSIKVKRYSDALDDLNAAIEADPALSEAYFKRASVLRHFCRYEDSENSYQKYLEFKSGDSNAEKELSQLH 128
Cdd:COG0457   7 DAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLAL 86

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 129 QAKSALETASTLYEskdiaKALEfvdkvvlvFSPACSKAKLLKVKLLMVSKDYSGAISETGYILKEDENNLEALLLRGRA 208
Cdd:COG0457  87 QALGRYEEALEDYD-----KALE--------LDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIA 153

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15242650 209 YYYLADHDIAQRHYQKGLRLDPEHSELKKAYFGLKKLLKKTKSAEDNANKGKLRVSAEEYKEAIALDPE 277
Cdd:COG0457 154 LEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAEL 222
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 199-350 2.11e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 50.19  E-value: 2.11e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 199 LEALLLRGRAYYYLADHDIAQRHYQKGLRLDPEHSELKKAYfglkkllkktksAEDNANKGKLRVSAEEYKEAIALDPeh 278
Cdd:COG4783   4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALL------------GEILLQLGDLDEAIVLLHEALELDP-- 69

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15242650 279 taNNVHLYLGLCKVSVRLGRGKDGLNSCNEALNIDAELIEALHQRGEAKLLLEDWEGAVEDLKQAAQNSQDM 350
Cdd:COG4783  70 --DEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 192-289 5.05e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 48.85  E-value: 5.05e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 192 LKEDENNLEALLLRGRAYYYLADHDIAQRHYQKGLRLDPEHSELKKAYfglkkllkktksAEDNANKGKLRVSAEEYKEA 271
Cdd:COG4235  10 LAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDL------------AEALLAAGDTEEAEELLERA 77

                        90
                ....*....|....*...
gi 15242650 272 IALDPEHTanNVHLYLGL 289
Cdd:COG4235  78 LALDPDNP--EALYLLGL 93
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 163-315 5.68e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 48.65  E-value: 5.68e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 163 ACSKAKLLKVKLLMVSKDYSGAISETGYILKEDENNLEALLLRGRAYYYLADHDIAQRHYQKGLRLDPEHSELKKAYfgl 242
Cdd:COG4783   2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNL--- 78

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15242650 243 kkllkktksAEDNANKGKLRVSAEEYKEAIALDPEHtannVHLYLGLCKVSVRLGRGKDGLNSCNEALNIDAE 315
Cdd:COG4783  79 ---------GLALLKAGDYDEALALLEKALKLDPEH----PEAYLRLARAYRALGRPDEAIAALEKALELDPD 138
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 68-234 7.28e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 48.08  E-value: 7.28e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650  68 DALDDLNAAIEADPALSEAYFKRASVLRHFCRYEDSENSYQKYLEFKSGDSNAEKELsqlhqaksaletASTLYESKDIA 147
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDL------------AEALLAAGDTE 68

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 148 KALEFVDKVvlvfspacskakllkvkllmvskdysgaisetgyiLKEDENNLEALLLRGRAYYYLADHDIAQRHYQKGLR 227
Cdd:COG4235  69 EAEELLERA-----------------------------------LALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLA 113


                ....*..
gi 15242650 228 LDPEHSE 234
Cdd:COG4235 114 LLPADAP 120
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
191-396 8.79e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 49.91  E-value: 8.79e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 191 ILKEDENNLEALLLRGRAYYYLADHDIAQRHYQKGLRLDPEHSELKKAYFglkkllkktKSAEDNANKGKLRVSAEEYKE 270
Cdd:COG4785  28 ALLFAAVLALAIALADLALALAAAALAAAALAAERIDRALALPDLAQLYY---------ERGVAYDSLGDYDLAIADFDQ 98

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 271 AIALDPEHTAnnVHLYLGLCkvSVRLGRGKDGLNSCNEALNIDAELIEALHQRGEAKLLLEDWEGAVEDLKQAAQ-NSQD 349
Cdd:COG4785  99 ALELDPDLAE--AYNNRGLA--YLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALElDPND 174

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*....
gi 15242650 350 MEIHESLGKAEKALKMSKRKDWYKILGISRTASISEIKKA--YKKLALQ 396
Cdd:COG4785 175 PERALWLYLAERKLDPEKALALLLEDWATAYLLQGDTEEAreLFKLALA 223
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 47-232 9.27e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 48.26  E-value: 9.27e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650  47 SVDAAELFERASQSIKVKRYSDALDDLNAAIEADPALSEAYFKRASVLRHFCRYEDSENSYQKYLEFKSGDSNAEKELsq 126
Cdd:COG4783   1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNL-- 78

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 127 lhqaksaletASTLYESKDIAKALEFVDKVvlvfspacskakllkvkllmvskdysgaisetgyiLKEDENNLEALLLRG 206
Cdd:COG4783  79 ----------GLALLKAGDYDEALALLEKA-----------------------------------LKLDPEHPEAYLRLA 113

                       170       180
                ....*....|....*....|....*.
gi 15242650 207 RAYYYLADHDIAQRHYQKGLRLDPEH 232
Cdd:COG4783 114 RAYRALGRPDEAIAALEKALELDPDD 139
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
77-344 5.77e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 47.69  E-value: 5.77e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650  77 IEADPALSEAYFKRASVLRHFCRYEDSENSYQKYLEFKSGDSNAekeLSQLhqaksaletASTLYESKDIAKALEFVDKV 156
Cdd:COG0457   1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEA---LYNL---------GLAYLRLGRYEEALADYEQA 68

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 157 vlvfspacskakllkvkllmvskdysgaisetgyiLKEDENNLEALLLRGRAYYYLADHDIAQRHYQKGLRLDPEHSElk 236
Cdd:COG0457  69 -----------------------------------LELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAE-- 111

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 237 kAYFGLkkllkktksAEDNANKGKLRVSAEEYKEAIALDPehtaNNVHLYLGLCKVSVRLGRGKDGLNSCNEALNIDAEL 316
Cdd:COG0457 112 -ALYNL---------GLALLELGRYDEAIEAYERALELDP----DDADALYNLGIALEKLGRYEEALELLEKLEAAALAA 177

                       250       260
                ....*....|....*....|....*...
gi 15242650 317 IEALHQRGEAKLLLEDWEGAVEDLKQAA 344
Cdd:COG0457 178 LLAAALGEAALALAAAEVLLALLLALEQ 205
ZUO1 COG5269
Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / ...
 351-441 8.02e-06

Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 227594 [Multi-domain]  Cd Length: 379  Bit Score: 48.11  E-value: 8.02e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 351 EIHESLGKAEKALKMSKR---KDW-----YKILGISR---TASISEIKKAYKKLALQWHPDKNV-GNREEAENKFREIAA 418
Cdd:COG5269  17 RIHSEYFKGRNVLNLYTRedfKNWkkvdlYALLGLSKyrtKAIPPQILKAHKKKVYKYHPDKTAaGGNKGCDEFFKLIQK 96

                        90       100
                ....*....|....*....|...
gi 15242650 419 AYEILGDDDKRARFDRGEDLEDM 441
Cdd:COG5269  97 AREVLGDRKLRLQYDSNDFDADV 119
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 39-147 1.19e-05

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 47.47  E-value: 1.19e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650   39 LVSALDGQSVDA----AELF-ERASQSIKVKRYSDALDDLNAAIEADPALSEAYFKRASVLRHFCRYEDSENSYQKYLEF 113
Cdd:PLN03088  20 LAVDLYTQAIDLdpnnAELYaDRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACMKLEEYQTAKAALEKGASL 99

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 15242650  114 KSGDSN-----------AEKELSQLHQAKSALETASTLYESKDIA 147
Cdd:PLN03088 100 APGDSRftklikecdekIAEEEKDLVQPVPSDLPSSVTAPPVEEA 144
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 252-364 5.28e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 43.26  E-value: 5.28e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 252 AEDNANKGKLRVSAEEYKEAIALDPehtaNNVHLYLGLCKVSVRLGRGKDGLNSCNEALNIDAELIEALHQRGEAKLLLE 331
Cdd:COG4783  11 AQALLLAGDYDEAEALLEKALELDP----DNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAG 86

                        90       100       110
                ....*....|....*....|....*....|....
gi 15242650 332 DWEGAVEDLKQA-AQNSQDMEIHESLGKAEKALK 364
Cdd:COG4783  87 DYDEALALLEKAlKLDPEHPEAYLRLARAYRALG 120
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
42-152 6.00e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 44.61  E-value: 6.00e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650  42 ALDGQSVDAAELFERASQSIKVKRYSDALDDLNAAIEADPALSEAYFKRASVLRHFCRYEDSENSYQKYLEFKSGDSNAE 121
Cdd:COG0457  68 ALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADAL 147

                        90       100       110
                ....*....|....*....|....*....|.
gi 15242650 122 KELSQLHQAKSALETASTLYESKDIAKALEF 152
Cdd:COG0457 148 YNLGIALEKLGRYEEALELLEKLEAAALAAL 178
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 34-152 7.62e-05

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 45.36  E-value: 7.62e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650    34 LLLQPLVSALDGQSVDAAELFERASQSIKVKRYS------------------DALDDLNAAIEADPALSEAYFKRASVLR 95
Cdd:TIGR00990 297 LGLKSPESKADESYEEAARAFEKALDLGKLGEKEaialnlrgtfkclkgkhlEALADLSKSIELDPRVTQSYIKRASMNL 376

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 15242650    96 HFCRYEDSENSYQKYLEFKSGDSNAEKELSQLHQAKSALETAstlyeSKDIAKALEF 152
Cdd:TIGR00990 377 ELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQA-----GKDYQKSIDL 428
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 129-278 7.82e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 42.49  E-value: 7.82e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 129 QAKSALETASTLYESKDIAKALEFVDKVvLVFSPACSKAKLLKVKLLMVSKDYSGAISETGYILKEDENNLEALLLRGRA 208
Cdd:COG4783   3 CAEALYALAQALLLAGDYDEAEALLEKA-LELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLA 81

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 209 YYYLADHDIAQRHYQKGLRLDPEHSELKKAYfglkkllkktksAEDNANKGKLRVSAEEYKEAIALDPEH 278
Cdd:COG4783  82 LLKAGDYDEALALLEKALKLDPEHPEAYLRL------------ARAYRALGRPDEAIAALEKALELDPDD 139
PTZ00100 PTZ00100
DnaJ chaperone protein; Provisional
 364-400 3.47e-04

DnaJ chaperone protein; Provisional


Pssm-ID: 240265  Cd Length: 116  Bit Score: 40.22  E-value: 3.47e-04
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 15242650  364 KMSKRKDwYKILGISRTASISEIKKAYKKLALQWHPD 400
Cdd:PTZ00100  61 PMSKSEA-YKILNISPTASKERIREAHKQLMLRNHPD 96
PHA03102 PHA03102
Small T antigen; Reviewed
 373-440 7.43e-04

Small T antigen; Reviewed


Pssm-ID: 222986 [Multi-domain]  Cd Length: 153  Bit Score: 40.04  E-value: 7.43e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650  373 KILGISRTA--SISEIKKAYKKLALQWHPDKnvGNREEaenKFREIAAAYEILGDDDKRARFDRGEDLED 440
Cdd:PHA03102   9 DLLGLPRSAwgNLPLMRKAYLRKCLEFHPDK--GGDEE---KMKELNTLYKKFRESVKSLRDLDGEEDSS 73
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 180-345 8.52e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.99  E-value: 8.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650   180 DYSGAISETGYILKEDENNLEALLLRGRAYYYLADHDIAQRHYQKGLRLDPEHS----ELKKAYFGL--------KKLLK 247
Cdd:TIGR02917  37 KYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALSLGYPKNqvlpLLARAYLLQgkfqqvldELPGK 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650   248 KTKSAEDNA-----------NKGKLRVSAEEYKEAIALDPEhtanNVHLYLGLCKVSVRLGRGKDGLNSCNEALNIDAEL 316
Cdd:TIGR02917 117 TLLDDEGAAellalrglaylGLGQLELAQKSYEQALAIDPR----SLYAKLGLAQLALAENRFDEARALIDEVLTADPGN 192

                         170       180
                  ....*....|....*....|....*....
gi 15242650   317 IEALHQRGEAKLLLEDWEGAVEDLKQAAQ 345
Cdd:TIGR02917 193 VDALLLKGDLLLSLGNIELALAAYRKAIA 221
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 27-233 1.23e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.61  E-value: 1.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650    27 FVFACQLLLLQPLVSALDGQSVDaaELFERASQSIKVKRYSDALDDLNAAIEADPALSEAYFKRASVLRHFCRYEDSENS 106
Cdd:TIGR02917   1 FIKITALLCIALALSACGDQSPE--ELIEAAKSYLQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKE 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650   107 YQKYLEFKSGDSNAEKELSQLH----QAKSALE--TASTLYESKDIAKALEFVD----------------KVVLVFSPAC 164
Cdd:TIGR02917  79 LRKALSLGYPKNQVLPLLARAYllqgKFQQVLDelPGKTLLDDEGAAELLALRGlaylglgqlelaqksyEQALAIDPRS 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15242650   165 SKAKLLKVKLLMVSKDYSGAISETGYILKEDENNLEALLLRGRAYYYLADHDIAQRHYQKGLRLDPEHS 233
Cdd:TIGR02917 159 LYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNI 227
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 42-142 1.24e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 39.02  E-value: 1.24e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650  42 ALDGQSVDAAELFERASQSIKVKRYSDALDDLNAAIEADPALSEAYFKRASVLRHFCRYEDSENSYQKYLEFKSGDSNAE 121
Cdd:COG4783  30 ALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAY 109

                        90       100
                ....*....|....*....|.
gi 15242650 122 KELSQLHQAKSALETASTLYE 142
Cdd:COG4783 110 LRLARAYRALGRPDEAIAALE 130
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
49-120 2.22e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 39.51  E-value: 2.22e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15242650  49 DAAELFERASQSIKVKRYSDALDDLNAAIEADPALSEAYFKRASVLRHFCRYEDSENSYQKYLEFKSGDSNA 120
Cdd:COG4785  72 LAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYA 143
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
49-117 4.38e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 38.74  E-value: 4.38e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15242650  49 DAAELFERASQSIKVKRYSDALDDLNAAIEADPALSEAYFKRASVLRHFCRYEDSENSYQKYLEFKSGD 117
Cdd:COG4785 106 LAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPND 174
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 265-359 5.22e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 37.29  E-value: 5.22e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650 265 AEEYKEAIALDPehtaNNVHLYLGLCKVSVRLGRGKDGLNSCNEALNIDAELIEALHQRGEAKLLLEDWEGAVEDLKQA- 343
Cdd:COG4235   3 IARLRQALAANP----NDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERAl 78

                        90
                ....*....|....*.
gi 15242650 344 AQNSQDMEIHESLGKA 359
Cdd:COG4235  79 ALDPDNPEALYLLGLA 94
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 200-232 8.40e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 33.96  E-value: 8.40e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 15242650    200 EALLLRGRAYYYLADHDIAQRHYQKGLRLDPEH 232
Cdd:smart00028   2 EALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 45-133 9.42e-03

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 38.53  E-value: 9.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242650    45 GQSVDAAELFERASQS-------------IKVKRYSDALDDLNAAIEA-DPALSEAYFKRA-----------------SV 93
Cdd:PRK11447  317 GDRARAVAQFEKALALdphssnrdkweslLKVNRYWLLIQQGDAALKAnNLAQAERLYQQArqvdntdsyavlglgdvAM 396

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 15242650    94 LRHfcRYEDSENSYQKYLEFKSGDSNAEKELSQLHQAKSA 133
Cdd:PRK11447  397 ARK--DYAAAERYYQQALRMDPGNTNAVRGLANLYRQQSP 434
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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