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Conserved domains on  [gi|15236267|ref|NP_195236|]
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plasma membrane intrinsic protein 3 [Arabidopsis thaliana]

Protein Classification

MIP/aquaporin family protein( domain architecture ID 11088534)

MIP (Major Intrinsic Protein)/aquaporin family protein similar to aquaporin that permits osmotically driven movement of water in both directions, and glycerol uptake facilitator protein that mediates glycerol diffusion across the cytoplasmic membrane via a pore-type mechanism

CATH:  1.20.1080.10
Gene Ontology:  GO:0055085|GO:0015267
PubMed:  11473620|8849412|11964478
SCOP:  3000508
TCDB:  1.A.8

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MIP pfam00230
Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two ...
 30-259 5.47e-94

Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two distinct types of channel properties: (1) specific water transport by the aquaporins, and (2) small neutral solutes transport, such as glycerol by the glycerol facilitators.


:

Pssm-ID: 395174 [Multi-domain]  Cd Length: 223  Bit Score: 276.51  E-value: 5.47e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267    30 ELKSWSFYRALIAEFIATLLFLYVTVATVIGHKKQTGPCDGVGLLGIAWAFGGMIFVLVYCTAGISGGHINPAVTFGLFL 109
Cdd:pfam00230   1 ELRSVSFLRAVIAEFLATLLFVFFGVGSALGVKKLVSSLAVSGLLAVALAFGLALATLVYCAGHISGAHLNPAVTLALLV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267   110 ARKVSLVRALGYMIAQCLGAICGVGFVKAFMKtPYNTLGGGANTVADGYSKGTALGAEIIGTFVLVYTVFSATDPKRSAR 189
Cdd:pfam00230  81 GRRFSLLRAIFYIVAQLLGAIAGAALLYGVTV-GLQRAGLFANTLAPGVNAGQAFVVEIILTFQLVYCVFATTDDRRNGS 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267   190 DSHIpvlAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIYNNekaWDDQWIFWVGPFLGALAAAAYH 259
Cdd:pfam00230 160 LGTV---APLAIGFAVFLNHLAGGPYTGASMNPARSFGPAVVLWK---WDDHWVYWVGPFIGAALGALVY 223
 
Name Accession Description Interval E-value
MIP pfam00230
Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two ...
 30-259 5.47e-94

Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two distinct types of channel properties: (1) specific water transport by the aquaporins, and (2) small neutral solutes transport, such as glycerol by the glycerol facilitators.


Pssm-ID: 395174 [Multi-domain]  Cd Length: 223  Bit Score: 276.51  E-value: 5.47e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267    30 ELKSWSFYRALIAEFIATLLFLYVTVATVIGHKKQTGPCDGVGLLGIAWAFGGMIFVLVYCTAGISGGHINPAVTFGLFL 109
Cdd:pfam00230   1 ELRSVSFLRAVIAEFLATLLFVFFGVGSALGVKKLVSSLAVSGLLAVALAFGLALATLVYCAGHISGAHLNPAVTLALLV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267   110 ARKVSLVRALGYMIAQCLGAICGVGFVKAFMKtPYNTLGGGANTVADGYSKGTALGAEIIGTFVLVYTVFSATDPKRSAR 189
Cdd:pfam00230  81 GRRFSLLRAIFYIVAQLLGAIAGAALLYGVTV-GLQRAGLFANTLAPGVNAGQAFVVEIILTFQLVYCVFATTDDRRNGS 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267   190 DSHIpvlAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIYNNekaWDDQWIFWVGPFLGALAAAAYH 259
Cdd:pfam00230 160 LGTV---APLAIGFAVFLNHLAGGPYTGASMNPARSFGPAVVLWK---WDDHWVYWVGPFIGAALGALVY 223
MIP cd00333
Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane ...
 38-262 4.53e-78

Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal cytosolic portion followed by six transmembrane helices, which might have arisen through gene duplication. On the basis of sequence similarity and functional characteristics, the superfamily can be subdivided into two major groups: water-selective channels called aquaporins (AQPs) and glycerol uptake facilitators (GlpFs). AQPs are found in all three kingdoms of life, while GlpFs have been characterized only within microorganisms.


Pssm-ID: 238204  Cd Length: 228  Bit Score: 236.38  E-value: 4.53e-78
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267  38 RALIAEFIATLLFLYVTVATVIGHKKQTGpcDGVGLLGIAWAFGGMIFVLVYCTAGISGGHINPAVTFGLFLARKVSLVR 117
Cdd:cd00333   1 RKYLAEFLGTFLLVFFGCGSVLAVKLAGG--ASGGLLGIALAWGFAIFVLVYAVGHISGGHINPAVTLALAVGGRFPLIR 78

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267 118 ALGYMIAQCLGAICGVGFVKAFMKTPYNTLGGGANTVAD--------GYSKGTALGAEIIGTFVLVYTVFSATDPKRSAr 189
Cdd:cd00333  79 VIPYIIAQLLGAILGAALLYGLYYGLYLEFLGANNIVAGifgtypspGVSNGNAFFVEFIGTFILVLVVFATTDDPNGP- 157

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15236267 190 dsHIPVLAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIYNNEKAWDDQWIFWVGPFLGALAAAAYHQYI 262
Cdd:cd00333 158 --PPGGLAPLAIGLLVAAIGLAGGPITGASMNPARSLGPALFTGLARHWHYFWVYWVGPLIGAIAGALVYDYV 228
MIP TIGR00861
MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is ...
 42-259 3.42e-64

MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is large and diverse, possessing over 100 members that all form transmembrane channels. These channel proteins function in water, smallcarbohydrate (e.g., glycerol), urea, NH3, CO2 and possibly ion transport by an energy independent mechanism. They are found ubiquitously in bacteria, archaeaand eukaryotes. The MIP family contains two major groups of channels: aquaporins and glycerol facilitators.The known aquaporins cluster loosely together as do the known glycerol facilitators. MIP family proteins are believed to form aqueous pores that selectively allow passive transport of their solute(s) across the membrane with minimal apparent recognition. Aquaporins selectively transport water (but not glycerol) while glycerol facilitators selectively transport glycerol but not water. Some aquaporins can transport NH3 and CO2. Glycerol facilitators function as solute nonspecific channels, and may transport glycerol, dihydroxyacetone, propanediol, urea and other small neutral molecules in physiologically importantprocesses. Some members of the family, including the yeast FPS protein (TC #1.A.8.5.1) and tobacco NtTIPA may transport both water and small solutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273306 [Multi-domain]  Cd Length: 216  Bit Score: 200.60  E-value: 3.42e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267    42 AEFIATLLFLYVTVATVIG--HKKQTGPCDGVGLLGIAWAFGGMIFVLVYCTAGISGGHINPAVTFGLFLARKVSLVRAL 119
Cdd:TIGR00861   1 AEFLGTFLLVFFGVGSALGvnVAGAYGAVGGGQFLGVALAFGLAVATLVYCVGGISGAHLNPAVTIALLLGRRFPLKRVP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267   120 GYMIAQCLGAICGVGFVKAFMKTPYNTLGGGANTVADGYSKGTALGAEIIGTFVLVYTVFSATDpKRSARDSHIpvLAPL 199
Cdd:TIGR00861  81 VYIVAQLIGAILGAALLYGLTSGLFPGNLAVNGSASAGVSSGQAFFVEFIGTAILVLVIFATTD-DRNRVPRGG--FAPL 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267   200 PIGFAVFMVHLATIPITGTGINPARSFGAAVIyNNEKAWDDQWIFWVGPFLGALAAAAYH 259
Cdd:TIGR00861 158 AIGLLVFLIHLSMGPYTGTGMNPARSLGPALF-AGLAGWGNHWVYWVGPIIGAILGALVY 216
GlpF COG0580
Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) ...
 35-264 2.85e-59

Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) [Carbohydrate transport and metabolism];


Pssm-ID: 440345 [Multi-domain]  Cd Length: 232  Bit Score: 188.41  E-value: 2.85e-59
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267  35 SFYRALIAEFIAT--LLFLYVTVATVIGHKKQtgpcdGVGLLGIAWAFGGMIFVLVYCTAGISGGHINPAVTFGLFLARK 112
Cdd:COG0580   1 SLMKRLLAEFLGTfiLVLLGCGVVAVLAGTKG-----GIGWLGIALAWGLAVLAGVYAFGHISGAHLNPAVTLALAVAGR 75

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267 113 VSLVRALGYMIAQCLGAICGVGFVKAFMKTPYNTLGGGANTV-------ADGYSKGTALGAEIIGTFVLVYTVFSATDPK 185
Cdd:COG0580  76 FPWKDVLPYIIAQLLGAFLGAALVYLIYGGHFDATEDGGAKLgvfatspAIGYSLGAAFLTEIIGTFVLVFVILGITDKR 155

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267 186 RSARdshipVLAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIYNNEK---AWDDQWIFWVGPFLGALAAAAYHQYI 262
Cdd:COG0580 156 AAPG-----GLAPLAIGLLVAAIGLSLGPLTGYAINPARDLGPRLFHALGKggsDWGYLWVPIVAPILGAALAALLYRAL 230


                ..
gi 15236267 263 LR 264
Cdd:COG0580 231 FG 232
PLN00166 PLN00166
aquaporin TIP2; Provisional
 28-258 2.11e-37

aquaporin TIP2; Provisional


Pssm-ID: 165733  Cd Length: 250  Bit Score: 132.75  E-value: 2.11e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267   28 MGELKSWSFYRALIAEFIATLLFLYVTVATVIGHKKQT--GPCDGVGLLGIAWAFGGMIFVLVYCTAGISGGHINPAVTF 105
Cdd:PLN00166   9 LGDSFSVASLKAYLSEFIATLLFVFAGVGSAIAFAKLTsdAALDPAGLVAVAVAHAFALFVGVSIAANISGGHLNPAVTL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267  106 GLFLARKVSLVRALGYMIAQCLGAICGVgfvkAFMKTPYNTLGGGANTVADGYSKGTALGAEIIGTFVLVYTVF-SATDP 184
Cdd:PLN00166  89 GLAIGGNITIITGFFYWIAQCLGSIVAC----LLLVFVTNGESVPTHGVAAGLGAIEGVVMEIVVTFALVYTVYaTAADP 164

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15236267  185 KRSArdshIPVLAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIYNNekaWDDQWIFWVGPFL-GALAAAAY 258
Cdd:PLN00166 165 KKGS----LGTIAPIAIGFIVGANILAAGPFSGGSMNPARSFGPAVVSGD---FSQIWIYWVGPLVgGALAGLIY 232
 
Name Accession Description Interval E-value
MIP pfam00230
Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two ...
 30-259 5.47e-94

Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two distinct types of channel properties: (1) specific water transport by the aquaporins, and (2) small neutral solutes transport, such as glycerol by the glycerol facilitators.


Pssm-ID: 395174 [Multi-domain]  Cd Length: 223  Bit Score: 276.51  E-value: 5.47e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267    30 ELKSWSFYRALIAEFIATLLFLYVTVATVIGHKKQTGPCDGVGLLGIAWAFGGMIFVLVYCTAGISGGHINPAVTFGLFL 109
Cdd:pfam00230   1 ELRSVSFLRAVIAEFLATLLFVFFGVGSALGVKKLVSSLAVSGLLAVALAFGLALATLVYCAGHISGAHLNPAVTLALLV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267   110 ARKVSLVRALGYMIAQCLGAICGVGFVKAFMKtPYNTLGGGANTVADGYSKGTALGAEIIGTFVLVYTVFSATDPKRSAR 189
Cdd:pfam00230  81 GRRFSLLRAIFYIVAQLLGAIAGAALLYGVTV-GLQRAGLFANTLAPGVNAGQAFVVEIILTFQLVYCVFATTDDRRNGS 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267   190 DSHIpvlAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIYNNekaWDDQWIFWVGPFLGALAAAAYH 259
Cdd:pfam00230 160 LGTV---APLAIGFAVFLNHLAGGPYTGASMNPARSFGPAVVLWK---WDDHWVYWVGPFIGAALGALVY 223
MIP cd00333
Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane ...
 38-262 4.53e-78

Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal cytosolic portion followed by six transmembrane helices, which might have arisen through gene duplication. On the basis of sequence similarity and functional characteristics, the superfamily can be subdivided into two major groups: water-selective channels called aquaporins (AQPs) and glycerol uptake facilitators (GlpFs). AQPs are found in all three kingdoms of life, while GlpFs have been characterized only within microorganisms.


Pssm-ID: 238204  Cd Length: 228  Bit Score: 236.38  E-value: 4.53e-78
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267  38 RALIAEFIATLLFLYVTVATVIGHKKQTGpcDGVGLLGIAWAFGGMIFVLVYCTAGISGGHINPAVTFGLFLARKVSLVR 117
Cdd:cd00333   1 RKYLAEFLGTFLLVFFGCGSVLAVKLAGG--ASGGLLGIALAWGFAIFVLVYAVGHISGGHINPAVTLALAVGGRFPLIR 78

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267 118 ALGYMIAQCLGAICGVGFVKAFMKTPYNTLGGGANTVAD--------GYSKGTALGAEIIGTFVLVYTVFSATDPKRSAr 189
Cdd:cd00333  79 VIPYIIAQLLGAILGAALLYGLYYGLYLEFLGANNIVAGifgtypspGVSNGNAFFVEFIGTFILVLVVFATTDDPNGP- 157

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15236267 190 dsHIPVLAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIYNNEKAWDDQWIFWVGPFLGALAAAAYHQYI 262
Cdd:cd00333 158 --PPGGLAPLAIGLLVAAIGLAGGPITGASMNPARSLGPALFTGLARHWHYFWVYWVGPLIGAIAGALVYDYV 228
MIP TIGR00861
MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is ...
 42-259 3.42e-64

MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is large and diverse, possessing over 100 members that all form transmembrane channels. These channel proteins function in water, smallcarbohydrate (e.g., glycerol), urea, NH3, CO2 and possibly ion transport by an energy independent mechanism. They are found ubiquitously in bacteria, archaeaand eukaryotes. The MIP family contains two major groups of channels: aquaporins and glycerol facilitators.The known aquaporins cluster loosely together as do the known glycerol facilitators. MIP family proteins are believed to form aqueous pores that selectively allow passive transport of their solute(s) across the membrane with minimal apparent recognition. Aquaporins selectively transport water (but not glycerol) while glycerol facilitators selectively transport glycerol but not water. Some aquaporins can transport NH3 and CO2. Glycerol facilitators function as solute nonspecific channels, and may transport glycerol, dihydroxyacetone, propanediol, urea and other small neutral molecules in physiologically importantprocesses. Some members of the family, including the yeast FPS protein (TC #1.A.8.5.1) and tobacco NtTIPA may transport both water and small solutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273306 [Multi-domain]  Cd Length: 216  Bit Score: 200.60  E-value: 3.42e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267    42 AEFIATLLFLYVTVATVIG--HKKQTGPCDGVGLLGIAWAFGGMIFVLVYCTAGISGGHINPAVTFGLFLARKVSLVRAL 119
Cdd:TIGR00861   1 AEFLGTFLLVFFGVGSALGvnVAGAYGAVGGGQFLGVALAFGLAVATLVYCVGGISGAHLNPAVTIALLLGRRFPLKRVP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267   120 GYMIAQCLGAICGVGFVKAFMKTPYNTLGGGANTVADGYSKGTALGAEIIGTFVLVYTVFSATDpKRSARDSHIpvLAPL 199
Cdd:TIGR00861  81 VYIVAQLIGAILGAALLYGLTSGLFPGNLAVNGSASAGVSSGQAFFVEFIGTAILVLVIFATTD-DRNRVPRGG--FAPL 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267   200 PIGFAVFMVHLATIPITGTGINPARSFGAAVIyNNEKAWDDQWIFWVGPFLGALAAAAYH 259
Cdd:TIGR00861 158 AIGLLVFLIHLSMGPYTGTGMNPARSLGPALF-AGLAGWGNHWVYWVGPIIGAILGALVY 216
GlpF COG0580
Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) ...
 35-264 2.85e-59

Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) [Carbohydrate transport and metabolism];


Pssm-ID: 440345 [Multi-domain]  Cd Length: 232  Bit Score: 188.41  E-value: 2.85e-59
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267  35 SFYRALIAEFIAT--LLFLYVTVATVIGHKKQtgpcdGVGLLGIAWAFGGMIFVLVYCTAGISGGHINPAVTFGLFLARK 112
Cdd:COG0580   1 SLMKRLLAEFLGTfiLVLLGCGVVAVLAGTKG-----GIGWLGIALAWGLAVLAGVYAFGHISGAHLNPAVTLALAVAGR 75

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267 113 VSLVRALGYMIAQCLGAICGVGFVKAFMKTPYNTLGGGANTV-------ADGYSKGTALGAEIIGTFVLVYTVFSATDPK 185
Cdd:COG0580  76 FPWKDVLPYIIAQLLGAFLGAALVYLIYGGHFDATEDGGAKLgvfatspAIGYSLGAAFLTEIIGTFVLVFVILGITDKR 155

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267 186 RSARdshipVLAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIYNNEK---AWDDQWIFWVGPFLGALAAAAYHQYI 262
Cdd:COG0580 156 AAPG-----GLAPLAIGLLVAAIGLSLGPLTGYAINPARDLGPRLFHALGKggsDWGYLWVPIVAPILGAALAALLYRAL 230


                ..
gi 15236267 263 LR 264
Cdd:COG0580 231 FG 232
PLN00166 PLN00166
aquaporin TIP2; Provisional
 28-258 2.11e-37

aquaporin TIP2; Provisional


Pssm-ID: 165733  Cd Length: 250  Bit Score: 132.75  E-value: 2.11e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267   28 MGELKSWSFYRALIAEFIATLLFLYVTVATVIGHKKQT--GPCDGVGLLGIAWAFGGMIFVLVYCTAGISGGHINPAVTF 105
Cdd:PLN00166   9 LGDSFSVASLKAYLSEFIATLLFVFAGVGSAIAFAKLTsdAALDPAGLVAVAVAHAFALFVGVSIAANISGGHLNPAVTL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267  106 GLFLARKVSLVRALGYMIAQCLGAICGVgfvkAFMKTPYNTLGGGANTVADGYSKGTALGAEIIGTFVLVYTVF-SATDP 184
Cdd:PLN00166  89 GLAIGGNITIITGFFYWIAQCLGSIVAC----LLLVFVTNGESVPTHGVAAGLGAIEGVVMEIVVTFALVYTVYaTAADP 164

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15236267  185 KRSArdshIPVLAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIYNNekaWDDQWIFWVGPFL-GALAAAAY 258
Cdd:PLN00166 165 KKGS----LGTIAPIAIGFIVGANILAAGPFSGGSMNPARSFGPAVVSGD---FSQIWIYWVGPLVgGALAGLIY 232
PLN00027 PLN00027
aquaporin TIP; Provisional
 38-258 4.12e-36

aquaporin TIP; Provisional


Pssm-ID: 177664  Cd Length: 252  Bit Score: 129.52  E-value: 4.12e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267   38 RALIAEFIATLLFLYVTVATVIGHKKQT--GPCDGVGLLGIAWAFGGMIFVLVYCTAGISGGHINPAVTFGLFLARKVSL 115
Cdd:PLN00027  21 KAALAEFISTLIFVFAGEGSGMAFNKLTdnGSTTPAGLVAAALAHAFALFVAVSVGANISGGHVNPAVTFGAFIGGNITL 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267  116 VRALGYMIAQCLGAICGVgfvkAFMKTPYNTLGGGANTVADGYSKGTALGAEIIGTFVLVYTVF-SATDPKRsardSHIP 194
Cdd:PLN00027 101 LRGILYWIAQLLGSVVAC----LLLKFSTGGLETSAFSLSSGVGVWNAFVFEIVMTFGLVYTVYaTAVDPKK----GDLG 172

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15236267  195 VLAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIYNNekaWDDQWIFWVGPFLG-ALAAAAY 258
Cdd:PLN00027 173 IIAPIAIGFIVGANILAGGAFDGASMNPAVSFGPAVVSWT---WTNHWVYWAGPLIGgGIAGLVY 234
PRK05420 PRK05420
aquaporin Z; Provisional
 70-267 4.67e-34

aquaporin Z; Provisional


Pssm-ID: 235453 [Multi-domain]  Cd Length: 231  Bit Score: 123.15  E-value: 4.67e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267   70 GVGLLGIAWAFGGMIFVLVYCTAGISGGHINPAVTFGLFLARKVSLVRALGYMIAQCLGAICGVG--FVKAFMKTPYNTL 147
Cdd:PRK05420  33 GIGFLGVALAFGLTVLTMAYAVGHISGGHFNPAVSVGLWAGGRFPAKELVPYIIAQVVGGIAAAAvlYLIASGKAGFDLA 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267  148 GGG--ANTVAD----GYSKGTALGAEIIGTFVLVYTVFSATDPKRSARdshipvLAPLPIGFAVFMVHLATIPITGTGIN 221
Cdd:PRK05420 113 GSGfaSNGYGEhspgGYSLLAALVCEVVLTAFFLLVILGATDKRAPAG------FAPIAIGLALTLIHLISIPVTNTSVN 186

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 15236267  222 PARSFGAAVIYNNEkAWDDQWIFWVGPFLGALAAAAYHQYILRASA 267
Cdd:PRK05420 187 PARSTGVALFVGGW-ALEQLWLFWVAPIVGAIIGGLIYRLLLEKDD 231
PLN00167 PLN00167
aquaporin TIP5; Provisional
 38-256 1.65e-29

aquaporin TIP5; Provisional


Pssm-ID: 215085  Cd Length: 256  Bit Score: 112.30  E-value: 1.65e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267   38 RALIAEFIATLLFLYVTVATVIGHKK--QTGPCDGVGLLGIAWAFGGMIFVLVYCTAGISGGHINPAVTFGLFLARKVSL 115
Cdd:PLN00167  23 RSYLAEFISTFFFVFAAVGSAMSSRKlmPDAASDPSSLLIVAIANAFALSSAVYIAANISGGHVNPAVTFGMAVGGHISV 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267  116 VRALGYMIAQCLGAICGVGFVKAFM---KTPYNTLGGgantvadgysKGTALGAEIIG---TFVLVYTVFSATDPKRSAR 189
Cdd:PLN00167 103 PTAMFYWISQMLASVMACLFLKVTTvgqHVPTYKIAE----------EMTGFGASVLEgvlTFGLVYTVYAAGDPRRGLL 172

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15236267  190 DShipvLAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIYNNEKawdDQWIFWVGPFLGALAAA 256
Cdd:PLN00167 173 GA----IGPLAIGLVAGANVLAAGPFSGGSMNPACAFGSAVVAGSFK---NQAVYWVGPLLGGAVAG 232
PLN00184 PLN00184
aquaporin NIP1; Provisional
 22-256 5.14e-23

aquaporin NIP1; Provisional


Pssm-ID: 177778  Cd Length: 296  Bit Score: 95.47  E-value: 5.14e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267   22 PAPLLDMGELKSWS--FYRALIAEFIATLLFLYVTVATVIGHKKQTgpcDGVGLLGIAWAFGGMIFVLVYCTAGISGGHI 99
Cdd:PLN00184  37 PKPLKKQDSLLSVSvpFLQKLIAEVLGTYFLVFTGCASVVVNMQND---NVVTLPGIAIVWGLTIMVLIYSLGHISGAHI 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267  100 NPAVTFGLFLARKVSLVRALGYMIAQCLGAICGVGFVKAFMKTPYNTLGGGANTVADGYSKGTALGA---EIIGTFVLVY 176
Cdd:PLN00184 114 NPAVTIAFASCGRFPLKQVPAYVISQVIGSTLAAATLRLLFGLDHDVCSGKHDVFIGSSPVGSDLQAfvmEFIVTFYLMF 193

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267  177 TVFSATDPKRSardshIPVLAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIYNNEKAWddqWIFWVGPFLGALAAA 256
Cdd:PLN00184 194 IISGVATDNRA-----IGELAGLAIGSTVLLNVLIAAPVSSASMNPGRSLGPAMVYGCYKGI---WIYIVAPTLGAIAGA 265
PLN00026 PLN00026
aquaporin NIP; Provisional
 1-257 4.81e-22

aquaporin NIP; Provisional


Pssm-ID: 177663 [Multi-domain]  Cd Length: 298  Bit Score: 93.00  E-value: 4.81e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267    1 MSKEVSEEGKTHhgKDYVDPPPAPLldmgelkswSFYRALIAEFIATLLFLYVTVATVIGHKKQTGpcdGVGLLGIAWAF 80
Cdd:PLN00026  46 FPVEALEWGRLP--TCFCDLPPPDV---------SLTRKLGAEFVGTFILIFAATAGPIVNQKYDG---AETLIGNAACA 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267   81 GGMIFVLVYCTAGISGGHINPAVTFGLFLARKVSLVRALGYMIAQCLGAICGVGFVKAFMktpYNTLGGGAnTVADGySK 160
Cdd:PLN00026 112 GLAVMIVILSTGHISGAHLNPSLTIAFAALRHFPWKHVPAYIAAQVSASICASFALKGVF---HPFMSGGV-TVPSV-ST 186

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267  161 GTALGAEIIGTFVLVYTVFSATDPKRSARDshipvLAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIYNNEKAWdd 240
Cdd:PLN00026 187 GQAFALEFIITFNLLFVVTAVATDTRAVGE-----LAGIAVGATVMLNILVAGPSTGGSMNPVRTLGPAVAAGNYRAI-- 259

                        250
                 ....*....|....*..
gi 15236267  241 qWIFWVGPFLGALAAAA 257
Cdd:PLN00026 260 -WIYLVAPTLGALAGAG 275
PTZ00016 PTZ00016
aquaglyceroporin; Provisional
 19-263 1.01e-21

aquaglyceroporin; Provisional


Pssm-ID: 240230 [Multi-domain]  Cd Length: 294  Bit Score: 92.11  E-value: 1.01e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267   19 DPPPAPLLDMGELKSWsfYRALIAEFIATLLFLYV---TVATVIGHKKQtgpcdgVGLLGIA--WAFGgmIFVLVYCTAG 93
Cdd:PTZ00016  34 PPGGQNFWAPREYRPN--VREYVAEFLGTFVLLFFgegVVATTHTVGNN------GDYLAITigWGLG--VTFGLLVSAG 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267   94 ISGGHINPAVTFGLFLARKVSLVRALGYMIAQCLGAICGV--------GFVKA--FMKTPYNTLGGGANTVADGYSKGTA 163
Cdd:PTZ00016 104 ISGGHLNPAVTLGNAVFGKFPWKKLPGYFVAQLLGAFVGAacvyglyyGFFKDhgIPELPWETMANGFAGVFATYPREGN 183

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267  164 LGA---EIIGTFVLVYTVFSATDPKRSARDSHIPVlaplPIGFAVFMVHLATIPITGTGINPARSFGA----AVIYNNEK 236
Cdd:PTZ00016 184 FYAifsELILTAILLLVILAITDPNNCPAFNYLPV----AVGLLVFVIGISFGGNTGYALNPARDLGPrlfsAILWGSEV 259

                        250       260       270
                 ....*....|....*....|....*....|
gi 15236267  237 AWDDQWIFW---VGPFLGALAAAAYHQYIL 263
Cdd:PTZ00016 260 FTKDNYYFWvplVAPFVGAVLGMFLYDKFI 289
PLN00182 PLN00182
putative aquaporin NIP4; Provisional
 40-262 4.23e-20

putative aquaporin NIP4; Provisional


Pssm-ID: 165748  Cd Length: 283  Bit Score: 87.27  E-value: 4.23e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267   40 LIAEFIATLLFLYVTVATVIGHKKQTGPcdgVGLLGIAWAFGGMIFVLVYCTAGISGGHINPAVTFGLFLARKVSLVRAL 119
Cdd:PLN00182  45 LIAEMIGTYFIIFSGCGVVVVNVLYGGT---ITFPGICVTWGLIVMVMIYSTGHISGAHFNPAVTVTFAIFRRFPWYQVP 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267  120 GYMIAQCLGAICGVGFVK-AFMKTPYNTLGggaNTVADgySKGTALGAEIIGTFVLVYTVFSATDPKRSARDshipvLAP 198
Cdd:PLN00182 122 LYIGAQLTGSLLASLTLRlMFNVTPEAFFG---TTPTD--SSGQALVAEIIISFLLMFVISGVATDSRAVGE-----LAG 191

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15236267  199 LPIGFAVFMVHLATIPITGTGINPARSFGAAVIYNNEKAWddqWIFWVGPFLGALAAAAYHQYI 262
Cdd:PLN00182 192 IAVGMTIILNVFVAGPISGASMNPARSLGPAIVMGRYKGI---WVYIVGPFVGIIAGGFVYNLI 252
PLN00183 PLN00183
putative aquaporin NIP7; Provisional
 38-264 5.47e-17

putative aquaporin NIP7; Provisional


Pssm-ID: 215092  Cd Length: 274  Bit Score: 78.75  E-value: 5.47e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267   38 RALIAEFIATLLFLYvTVATVIGHKKQTGpcDGVGLLGIAWAFGGMIFVLVYCTAGISGGHINPAVT-----FGLFLARK 112
Cdd:PLN00183  46 RMVLAEMVGTFILMF-CVCGIIASTQLSG--GEVGLLEYAATAGLTVVVVVFSIGSISGAHVNPSVTiafatFGHFPWSK 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267  113 VSLvralgYMIAQCLGAICG------VGFVKAFMKTPYNTLGGgantvadgyskGTALGAEIIGTFVLVYTVFSATDPKR 186
Cdd:PLN00183 123 VPL-----YITAQTVGSVLAtyvgvsVYGVKADLMTTKPAQGC-----------SSAFWVEFIATFIVMFLAASLTSQPQ 186

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236267  187 SARDshipvLAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIynnekAWD--DQWIFWVGPFLGALAAA-AYHQYIL 263
Cdd:PLN00183 187 SLGH-----LSGFVIGIAIGLAVLITGPVSGGSMNPARSLGPAIV-----SWDfkDIWIYITAPTIGAVAGAlMFHLLRL 256


                 .
gi 15236267  264 R 264
Cdd:PLN00183 257 R 257
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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