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Conserved domains on  [gi|15235527|ref|NP_194630|]
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Enoyl-CoA hydratase/isomerase family [Arabidopsis thaliana]

Protein Classification

fatty acid beta-oxidation multifunctional protein( domain architecture ID 1002730)

fatty acid beta-oxidation multifunctional protein, similar to human peroxisomal bifunctional enzyme that possesses 2-enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase, and delta 3, delta 2-enoyl-CoA isomerase activities

Gene Ontology:  GO:0019395|GO:0006635
PubMed:  2303409

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
fadJ super family cl35999
fatty acid oxidation complex subunit alpha FadJ;
8-708 1.43e-155

fatty acid oxidation complex subunit alpha FadJ;


The actual alignment was detected with superfamily member PRK11154:

Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 467.45  E-value: 1.43e-155
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527    8 TMEVGNDGVAVITISNP--PVNSLASPIISGLKEKFRDANQRNDVKAIVLI-GNNGRFSGGFDINVFQQVHKTGDLSLMP 84
Cdd:PRK11154   8 TLNVREDNIAVITIDVPgeKMNTLKAEFAEQVRAILKQLREDKELKGVVFIsGKPDNFIAGADINMLAACKTAQEAEALA 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   85 EVSVELVcNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAA--PKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATD 162
Cdd:PRK11154  88 RQGQQLF-AEIEALPIPVVAAIHGACLGGGLELALACHYRVCTddPKTVLGLPEVQLGLLPGSGGTQRLPRLIGVSTALD 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  163 MILLSKSISSEEGHKLGLIDALVPPGDVLSTsrkwALDIAEGRKPFLQSLHRTDKI-GSLSEARAILKN--SRQLAKKIA 239
Cdd:PRK11154 167 MILTGKQLRAKQALKLGLVDDVVPHSILLEV----AVELAKKGKPARRPLPVRERLlEGNPLGRALLFKqaRKKTLAKTQ 242
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  240 PNMPQHHACIEVIEEGIIHGGYSGVLKEAEVFKQLVLSDTAKGLVHVFFAqraTSKVPNVTDVGLKPRPIKKVAVIGGGL 319
Cdd:PRK11154 243 GNYPAPERILDVVRTGLEKGMSSGYEAEARAFGELAMTPESAALRSIFFA---TTEMKKDTGSDAKPRPVNKVGVLGGGL 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  320 MGSGIA--TALLlSNIRVVLKEINSEFLMKGIKSVEANMKSLVSRGKLTQDKAGKALSLFKGVLDYTEFNDVDMVIEAVI 397
Cdd:PRK11154 320 MGGGIAyvTATK-AGLPVRIKDINPQGINHALKYSWDLLDKKVKRRHLKPSERDKQMALISGTTDYRGFKHADVVIEAVF 398
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  398 ENIQLKQNIFKEIEKVCSPHCILASNTSTIDLDVIGEKTNSKDRIVGAHFFSPAHLMPLLEIVRSKNTSAQVILDLMAVG 477
Cdd:PRK11154 399 EDLALKQQMVAEVEQNCAPHTIFASNTSSLPIGQIAAAAARPEQVIGLHYFSPVEKMPLVEVIPHAKTSAETIATTVALA 478
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  478 KAIKKVPVVVGNCIGFAVNRTFFPY-SQAAHMLANlGVDLFRIDSVITSFGLPLGPFQLGDLAGHGIGLAVGPIYAKVYG 556
Cdd:PRK11154 479 KKQGKTPIVVRDGAGFYVNRILAPYiNEAARLLLE-GEPIEHIDAALVKFGFPVGPITLLDEVGIDVGTKIIPILEAALG 557
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  557 DRMFRSPMTELLLKSGRNGKINGRGYYIYEKGSKPK---PDPSVLsiveksrKLTNIMPGGKpisVTDKEIVEMILFPVV 633
Cdd:PRK11154 558 ERFSAPAAFDKLLNDDRKGRKNGRGFYLYGQKGKKSkkqVDESVY-------PLLGITPQSR---LSANEIAERCVMLML 627
                        650       660       670       680       690       700       710
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15235527  634 NEACRVLDEGVVIRASDLDIASVLGMSFPSYRGGIVFWADTVGPKYIYERLKKLSETYGSFFKPSRYLEERAMNG 708
Cdd:PRK11154 628 NEAVRCLDEGIIRSARDGDIGAVFGIGFPPFLGGPFRYMDSLGAGEVVAILERLAAQYGDRFTPCERLVEMAERG 702
 
Name Accession Description Interval E-value
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
8-708 1.43e-155

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 467.45  E-value: 1.43e-155
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527    8 TMEVGNDGVAVITISNP--PVNSLASPIISGLKEKFRDANQRNDVKAIVLI-GNNGRFSGGFDINVFQQVHKTGDLSLMP 84
Cdd:PRK11154   8 TLNVREDNIAVITIDVPgeKMNTLKAEFAEQVRAILKQLREDKELKGVVFIsGKPDNFIAGADINMLAACKTAQEAEALA 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   85 EVSVELVcNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAA--PKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATD 162
Cdd:PRK11154  88 RQGQQLF-AEIEALPIPVVAAIHGACLGGGLELALACHYRVCTddPKTVLGLPEVQLGLLPGSGGTQRLPRLIGVSTALD 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  163 MILLSKSISSEEGHKLGLIDALVPPGDVLSTsrkwALDIAEGRKPFLQSLHRTDKI-GSLSEARAILKN--SRQLAKKIA 239
Cdd:PRK11154 167 MILTGKQLRAKQALKLGLVDDVVPHSILLEV----AVELAKKGKPARRPLPVRERLlEGNPLGRALLFKqaRKKTLAKTQ 242
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  240 PNMPQHHACIEVIEEGIIHGGYSGVLKEAEVFKQLVLSDTAKGLVHVFFAqraTSKVPNVTDVGLKPRPIKKVAVIGGGL 319
Cdd:PRK11154 243 GNYPAPERILDVVRTGLEKGMSSGYEAEARAFGELAMTPESAALRSIFFA---TTEMKKDTGSDAKPRPVNKVGVLGGGL 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  320 MGSGIA--TALLlSNIRVVLKEINSEFLMKGIKSVEANMKSLVSRGKLTQDKAGKALSLFKGVLDYTEFNDVDMVIEAVI 397
Cdd:PRK11154 320 MGGGIAyvTATK-AGLPVRIKDINPQGINHALKYSWDLLDKKVKRRHLKPSERDKQMALISGTTDYRGFKHADVVIEAVF 398
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  398 ENIQLKQNIFKEIEKVCSPHCILASNTSTIDLDVIGEKTNSKDRIVGAHFFSPAHLMPLLEIVRSKNTSAQVILDLMAVG 477
Cdd:PRK11154 399 EDLALKQQMVAEVEQNCAPHTIFASNTSSLPIGQIAAAAARPEQVIGLHYFSPVEKMPLVEVIPHAKTSAETIATTVALA 478
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  478 KAIKKVPVVVGNCIGFAVNRTFFPY-SQAAHMLANlGVDLFRIDSVITSFGLPLGPFQLGDLAGHGIGLAVGPIYAKVYG 556
Cdd:PRK11154 479 KKQGKTPIVVRDGAGFYVNRILAPYiNEAARLLLE-GEPIEHIDAALVKFGFPVGPITLLDEVGIDVGTKIIPILEAALG 557
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  557 DRMFRSPMTELLLKSGRNGKINGRGYYIYEKGSKPK---PDPSVLsiveksrKLTNIMPGGKpisVTDKEIVEMILFPVV 633
Cdd:PRK11154 558 ERFSAPAAFDKLLNDDRKGRKNGRGFYLYGQKGKKSkkqVDESVY-------PLLGITPQSR---LSANEIAERCVMLML 627
                        650       660       670       680       690       700       710
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15235527  634 NEACRVLDEGVVIRASDLDIASVLGMSFPSYRGGIVFWADTVGPKYIYERLKKLSETYGSFFKPSRYLEERAMNG 708
Cdd:PRK11154 628 NEAVRCLDEGIIRSARDGDIGAVFGIGFPPFLGGPFRYMDSLGAGEVVAILERLAAQYGDRFTPCERLVEMAERG 702
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
15-705 3.96e-120

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 376.87  E-value: 3.96e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527    15 GVAVITISNP--PVNSLASPIISGLKEKFRDANQRNDVKAIVLI-GNNGRFSGGFDINVFQQVHKTGDLSLMPEVSVELV 91
Cdd:TIGR02441  22 DVAVVKIDSPnsKVNTLSKELFAEFKEVMNELWTNEAIKSAVLIsGKPGSFVAGADIQMIAACKTAQEVTQLSQEGQEMF 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527    92 cNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAP--KAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMILLSKS 169
Cdd:TIGR02441 102 -ERIEKSQKPIVAAISGSCLGGGLELALACHYRIATKdrKTLLGLPEVMLGLLPGAGGTQRLPKLTGVPAALDMMLTGKK 180
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   170 ISSEEGHKLGLIDALVPP-GDVL------------STSRKWALDIAEGR------KPFLQSLhrTDKIGSLSEAR-AILK 229
Cdd:TIGR02441 181 IRADRAKKMGIVDQLVDPlGPGLkpaeentieyleEVAVKFAQGLANGKlsinrdKGLVHKI--TQYVMTNPFVRqQVYK 258
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   230 NSR-QLAKKIAPNMPQHHACIEVIEEGIIHGGYSGVLKEAEVFKQLVLSDTAKGLVHVFFAQRATSKvpnvTDVGLKPRP 308
Cdd:TIGR02441 259 TAEdKVMKQTKGLYPAPLKILDVVRTGYDQGPDAGYEAESKAFGELSMTFESKALIGLFHGQTDCKK----NKFGKPQRP 334
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   309 IKKVAVIGGGLMGSGIATALLLSNIRVVLKEINSEFLMKGIKSVEANMKSLVSRGKLTQDKAGKALSLFKGVLDYTEFND 388
Cdd:TIGR02441 335 VKTLAVLGAGLMGAGIAQVSVDKGLKTVLKDATPAGLDRGQQQVFKGLNKKVKRKKITSLERDSILSNLTPTLDYSGFKN 414
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   389 VDMVIEAVIENIQLKQNIFKEIEKVCSPHCILASNTSTIDLDVIGEKTNSKDRIVGAHFFSPAHLMPLLEIVRSKNTSAQ 468
Cdd:TIGR02441 415 ADMVIEAVFEDLSLKHKVIKEVEAVVPPHCIIASNTSALPIKDIAAVSSRPEKVIGMHYFSPVDKMQLLEIITHDGTSKD 494
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   469 VILDLMAVGKAIKKVPVVVGNCIGFAVNRTFFPYSQAAHMLANLGVDLFRIDSVITSFGLPLGPFQLGDLAGHGIGLAVG 548
Cdd:TIGR02441 495 TLASAVAVGLKQGKVVIVVKDGPGFYTTRCLGPMLAEVIRLLQEGVDPKKLDKLTTKFGFPVGAATLADEVGVDVAEHVA 574
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   549 PIYAKVYGDRmFRSPMTEL---LLKSGRNGKINGRGYYIYEKGSKP-KPDPSVLSIVEKSRKLTnimpgGKPISVTDKEI 624
Cdd:TIGR02441 575 EDLGKAFGER-FGGGSAELlseLVKAGFLGRKSGKGIFIYQEGKKGsKKVNSDADEILAQYKLP-----PKAEVSSPEDI 648
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   625 VEMILFPVVNEACRVLDEGVVIRASDLDIASVLGMSFPSYRGGIVFWADTVGPKYIYERLKKLSETYGSFFKPSRYLEER 704
Cdd:TIGR02441 649 QIRLVSRFVNEAVLCLEEGILASPSEGDIGAVFGLGFPPFLGGPFRFVDLYGADKLVDKMEKYAAAYGVQFTPCQLLLDH 728

                  .
gi 15235527   705 A 705
Cdd:TIGR02441 729 A 729
FadB COG1250
3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA ...
308-585 2.25e-99

3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA dehydrogenase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440862 [Multi-domain]  Cd Length: 281  Bit Score: 307.04  E-value: 2.25e-99
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527 308 PIKKVAVIGGGLMGSGIATALLLSNIRVVLKEINSEFLMKGIKSVEANMKSLVSRGKLTQDKAGKALSLFKGVLDYTEFN 387
Cdd:COG1250   1 EIKKVAVIGAGTMGAGIAAVFANAGYEVVLLDISPEALERARARIAKLLDKLVKKGKLTEEEADAALARITPTTDLAALA 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527 388 DVDMVIEAVIENIQLKQNIFKEIEKVCSPHCILASNTSTIDLDVIGEKTNSKDRIVGAHFFSPAHLMPLLEIVRSKNTSA 467
Cdd:COG1250  81 DADLVIEAVPEDLDLKQEVFAELDAVAPPDAILASNTSSLSITELAAATKRPERFIGLHFFNPVPLMPLVEVIRGPATSD 160
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527 468 QVILDLMAVGKAIKKVPVVVGNCIGFAVNRTFFPY-SQAAHMLANLGVDLFRIDSVIT-SFGLPLGPFQLGDLAGHGIGL 545
Cdd:COG1250 161 ETVATAVAFARRLGKTPVVVKDTPGFIVNRILVPYlNEAIRLLEEGVASPEDIDAAMRlGFGFPMGPFELADLVGLDTAL 240
                       250       260       270       280
                ....*....|....*....|....*....|....*....|.
gi 15235527 546 AVGPIYAKVYGDRMFR-SPMTELLLKSGRNGKINGRGYYIY 585
Cdd:COG1250 241 AVLEVLYEALGDPRYRpPPLLKKLVEAGRLGRKTGRGFYDY 281
3HCDH_N pfam02737
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda ...
311-490 3.99e-74

3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda crystallin.


Pssm-ID: 397037 [Multi-domain]  Cd Length: 180  Bit Score: 237.44  E-value: 3.99e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   311 KVAVIGGGLMGSGIATALLLSNIRVVLKEINSEFLMKGIKSVEANMKSLVSRGKLTQDKAGKALSLFKGVLDYTEFNDVD 390
Cdd:pfam02737   1 KVAVIGAGTMGAGIAQVFALAGLEVVLVDISEEALEKALERIESSLERLVEKGRITEEEVDAALARISFTTDLAAAVDAD 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   391 MVIEAVIENIQLKQNIFKEIEKVCSPHCILASNTSTIDLDVIGEKTNSKDRIVGAHFFSPAHLMPLLEIVRSKNTSAQVI 470
Cdd:pfam02737  81 LVIEAVPENLELKRKLFAELDAIAPPDAILATNTSSLSITELAAATKRPERFIGLHFFNPPPLMPLVEVVRGEKTSPETV 160
                         170       180
                  ....*....|....*....|
gi 15235527   471 LDLMAVGKAIKKVPVVVGNC 490
Cdd:pfam02737 161 ATTVELAKKIGKTPVVVKDT 180
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
7-201 9.52e-47

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 164.27  E-value: 9.52e-47
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   7 VTMEVgNDGVAVITISNPP-VNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINVFQQVHKTGDLSLMPE 85
Cdd:cd06558   1 VLVER-DGGVATITLNRPEkRNALSLEMLDELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAALSDAGEEARAFI 79
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  86 VSVELVCNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMIL 165
Cdd:cd06558  80 RELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLL 159
                       170       180       190
                ....*....|....*....|....*....|....*.
gi 15235527 166 LSKSISSEEGHKLGLIDALVPPGDVLSTSRKWALDI 201
Cdd:cd06558 160 TGRRISAEEALELGLVDEVVPDEELLAAALELARRL 195
 
Name Accession Description Interval E-value
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
8-708 1.43e-155

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 467.45  E-value: 1.43e-155
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527    8 TMEVGNDGVAVITISNP--PVNSLASPIISGLKEKFRDANQRNDVKAIVLI-GNNGRFSGGFDINVFQQVHKTGDLSLMP 84
Cdd:PRK11154   8 TLNVREDNIAVITIDVPgeKMNTLKAEFAEQVRAILKQLREDKELKGVVFIsGKPDNFIAGADINMLAACKTAQEAEALA 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   85 EVSVELVcNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAA--PKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATD 162
Cdd:PRK11154  88 RQGQQLF-AEIEALPIPVVAAIHGACLGGGLELALACHYRVCTddPKTVLGLPEVQLGLLPGSGGTQRLPRLIGVSTALD 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  163 MILLSKSISSEEGHKLGLIDALVPPGDVLSTsrkwALDIAEGRKPFLQSLHRTDKI-GSLSEARAILKN--SRQLAKKIA 239
Cdd:PRK11154 167 MILTGKQLRAKQALKLGLVDDVVPHSILLEV----AVELAKKGKPARRPLPVRERLlEGNPLGRALLFKqaRKKTLAKTQ 242
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  240 PNMPQHHACIEVIEEGIIHGGYSGVLKEAEVFKQLVLSDTAKGLVHVFFAqraTSKVPNVTDVGLKPRPIKKVAVIGGGL 319
Cdd:PRK11154 243 GNYPAPERILDVVRTGLEKGMSSGYEAEARAFGELAMTPESAALRSIFFA---TTEMKKDTGSDAKPRPVNKVGVLGGGL 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  320 MGSGIA--TALLlSNIRVVLKEINSEFLMKGIKSVEANMKSLVSRGKLTQDKAGKALSLFKGVLDYTEFNDVDMVIEAVI 397
Cdd:PRK11154 320 MGGGIAyvTATK-AGLPVRIKDINPQGINHALKYSWDLLDKKVKRRHLKPSERDKQMALISGTTDYRGFKHADVVIEAVF 398
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  398 ENIQLKQNIFKEIEKVCSPHCILASNTSTIDLDVIGEKTNSKDRIVGAHFFSPAHLMPLLEIVRSKNTSAQVILDLMAVG 477
Cdd:PRK11154 399 EDLALKQQMVAEVEQNCAPHTIFASNTSSLPIGQIAAAAARPEQVIGLHYFSPVEKMPLVEVIPHAKTSAETIATTVALA 478
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  478 KAIKKVPVVVGNCIGFAVNRTFFPY-SQAAHMLANlGVDLFRIDSVITSFGLPLGPFQLGDLAGHGIGLAVGPIYAKVYG 556
Cdd:PRK11154 479 KKQGKTPIVVRDGAGFYVNRILAPYiNEAARLLLE-GEPIEHIDAALVKFGFPVGPITLLDEVGIDVGTKIIPILEAALG 557
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  557 DRMFRSPMTELLLKSGRNGKINGRGYYIYEKGSKPK---PDPSVLsiveksrKLTNIMPGGKpisVTDKEIVEMILFPVV 633
Cdd:PRK11154 558 ERFSAPAAFDKLLNDDRKGRKNGRGFYLYGQKGKKSkkqVDESVY-------PLLGITPQSR---LSANEIAERCVMLML 627
                        650       660       670       680       690       700       710
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15235527  634 NEACRVLDEGVVIRASDLDIASVLGMSFPSYRGGIVFWADTVGPKYIYERLKKLSETYGSFFKPSRYLEERAMNG 708
Cdd:PRK11154 628 NEAVRCLDEGIIRSARDGDIGAVFGIGFPPFLGGPFRYMDSLGAGEVVAILERLAAQYGDRFTPCERLVEMAERG 702
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
14-708 1.01e-121

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 379.98  E-value: 1.01e-121
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   14 DGVAVITISNP-PVNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINVFQQVHKTGDLSLMPEVS-VELV 91
Cdd:PRK11730  15 DGIAELVFDAPgSVNKLDRATLASLGEALDALEAQSDLKGLLLTSAKDAFIVGADITEFLSLFAAPEEELSQWLHfANSI 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   92 CNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMILLSKSIS 171
Cdd:PRK11730  95 FNRLEDLPVPTVAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLIGADNALEWIAAGKDVR 174
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  172 SEEGHKLGLIDALVPPGDVLSTSR---KWA----LDIAEGRKPFLQSL--HRTDKIGSLSEARAilknsrQLAKKIAPNM 242
Cdd:PRK11730 175 AEDALKVGAVDAVVAPEKLQEAALallKQAiagkLDWKARRQPKLEPLklSKIEAMMSFTTAKG------MVAQKAGKHY 248
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  243 PQHHACIEVIEEGIiHGGYSGVLK-EAEVFKQLVLSDTAKGLVHVFFAQRATSKVPNVTDVGLKPrpIKKVAVIGGGLMG 321
Cdd:PRK11730 249 PAPMTAVKTIEAAA-GLGRDEALElEAKGFVKLAKTNVARALVGIFLNDQYVKGKAKKLAKDAKP--VKQAAVLGAGIMG 325
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  322 SGIATALLLSNIRVVLKEINSEFLMKGIKsvEANmKSL---VSRGKLTQDKAGKALSLFKGVLDYTEFNDVDMVIEAVIE 398
Cdd:PRK11730 326 GGIAYQSASKGVPVIMKDINQKALDLGMT--EAA-KLLnkqVERGKIDGAKMAGVLSSIRPTLDYAGFERVDVVVEAVVE 402
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  399 NIQLKQNIFKEIEKVCSPHCILASNTSTIDLDVIGEKTNSKDRIVGAHFFSPAHLMPLLEIVRSKNTSAQVILDLMAVGK 478
Cdd:PRK11730 403 NPKVKAAVLAEVEQKVREDTILASNTSTISISLLAKALKRPENFCGMHFFNPVHRMPLVEVIRGEKTSDETIATVVAYAS 482
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  479 AIKKVPVVVGNCIGFAVNRTFFPYSQAAHMLANLGVDLFRIDSVIT-SFGLPLGPFQLGDLAGHGIGLAVGPIYAKVYGD 557
Cdd:PRK11730 483 KMGKTPIVVNDCPGFFVNRVLFPYFAGFSQLLRDGADFRQIDKVMEkQFGWPMGPAYLLDVVGIDTAHHAQAVMAEGFPD 562
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  558 RM---FRSPMtELLLKSGRNGKINGRGYYIYEKGSKPKP----DPSVL----SIVEKSRkltnimpggkpiSVTDKEIVE 626
Cdd:PRK11730 563 RMkkdYRDAI-DVLFEAKRFGQKNGKGFYRYEEDKKGKPkkevDPAVYellaPVVQPKR------------EFSDEEIIA 629
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  627 MILFPVVNEACRVLDEGVVIRASDLDIASVLGMSFPSYRGGIVFWADTVGPKYIYERLKKLSEtYGSFFKPSRYLEERAM 706
Cdd:PRK11730 630 RMMIPMINEVVRCLEEGIVASPAEADMALVYGLGFPPFRGGAFRYLDTLGVANYVALADKYAH-LGPLYQVPEGLREMAA 708

                 ..
gi 15235527  707 NG 708
Cdd:PRK11730 709 NG 710
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
15-705 3.96e-120

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 376.87  E-value: 3.96e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527    15 GVAVITISNP--PVNSLASPIISGLKEKFRDANQRNDVKAIVLI-GNNGRFSGGFDINVFQQVHKTGDLSLMPEVSVELV 91
Cdd:TIGR02441  22 DVAVVKIDSPnsKVNTLSKELFAEFKEVMNELWTNEAIKSAVLIsGKPGSFVAGADIQMIAACKTAQEVTQLSQEGQEMF 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527    92 cNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAP--KAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMILLSKS 169
Cdd:TIGR02441 102 -ERIEKSQKPIVAAISGSCLGGGLELALACHYRIATKdrKTLLGLPEVMLGLLPGAGGTQRLPKLTGVPAALDMMLTGKK 180
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   170 ISSEEGHKLGLIDALVPP-GDVL------------STSRKWALDIAEGR------KPFLQSLhrTDKIGSLSEAR-AILK 229
Cdd:TIGR02441 181 IRADRAKKMGIVDQLVDPlGPGLkpaeentieyleEVAVKFAQGLANGKlsinrdKGLVHKI--TQYVMTNPFVRqQVYK 258
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   230 NSR-QLAKKIAPNMPQHHACIEVIEEGIIHGGYSGVLKEAEVFKQLVLSDTAKGLVHVFFAQRATSKvpnvTDVGLKPRP 308
Cdd:TIGR02441 259 TAEdKVMKQTKGLYPAPLKILDVVRTGYDQGPDAGYEAESKAFGELSMTFESKALIGLFHGQTDCKK----NKFGKPQRP 334
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   309 IKKVAVIGGGLMGSGIATALLLSNIRVVLKEINSEFLMKGIKSVEANMKSLVSRGKLTQDKAGKALSLFKGVLDYTEFND 388
Cdd:TIGR02441 335 VKTLAVLGAGLMGAGIAQVSVDKGLKTVLKDATPAGLDRGQQQVFKGLNKKVKRKKITSLERDSILSNLTPTLDYSGFKN 414
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   389 VDMVIEAVIENIQLKQNIFKEIEKVCSPHCILASNTSTIDLDVIGEKTNSKDRIVGAHFFSPAHLMPLLEIVRSKNTSAQ 468
Cdd:TIGR02441 415 ADMVIEAVFEDLSLKHKVIKEVEAVVPPHCIIASNTSALPIKDIAAVSSRPEKVIGMHYFSPVDKMQLLEIITHDGTSKD 494
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   469 VILDLMAVGKAIKKVPVVVGNCIGFAVNRTFFPYSQAAHMLANLGVDLFRIDSVITSFGLPLGPFQLGDLAGHGIGLAVG 548
Cdd:TIGR02441 495 TLASAVAVGLKQGKVVIVVKDGPGFYTTRCLGPMLAEVIRLLQEGVDPKKLDKLTTKFGFPVGAATLADEVGVDVAEHVA 574
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   549 PIYAKVYGDRmFRSPMTEL---LLKSGRNGKINGRGYYIYEKGSKP-KPDPSVLSIVEKSRKLTnimpgGKPISVTDKEI 624
Cdd:TIGR02441 575 EDLGKAFGER-FGGGSAELlseLVKAGFLGRKSGKGIFIYQEGKKGsKKVNSDADEILAQYKLP-----PKAEVSSPEDI 648
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   625 VEMILFPVVNEACRVLDEGVVIRASDLDIASVLGMSFPSYRGGIVFWADTVGPKYIYERLKKLSETYGSFFKPSRYLEER 704
Cdd:TIGR02441 649 QIRLVSRFVNEAVLCLEEGILASPSEGDIGAVFGLGFPPFLGGPFRFVDLYGADKLVDKMEKYAAAYGVQFTPCQLLLDH 728

                  .
gi 15235527   705 A 705
Cdd:TIGR02441 729 A 729
FadB COG1250
3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA ...
308-585 2.25e-99

3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA dehydrogenase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440862 [Multi-domain]  Cd Length: 281  Bit Score: 307.04  E-value: 2.25e-99
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527 308 PIKKVAVIGGGLMGSGIATALLLSNIRVVLKEINSEFLMKGIKSVEANMKSLVSRGKLTQDKAGKALSLFKGVLDYTEFN 387
Cdd:COG1250   1 EIKKVAVIGAGTMGAGIAAVFANAGYEVVLLDISPEALERARARIAKLLDKLVKKGKLTEEEADAALARITPTTDLAALA 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527 388 DVDMVIEAVIENIQLKQNIFKEIEKVCSPHCILASNTSTIDLDVIGEKTNSKDRIVGAHFFSPAHLMPLLEIVRSKNTSA 467
Cdd:COG1250  81 DADLVIEAVPEDLDLKQEVFAELDAVAPPDAILASNTSSLSITELAAATKRPERFIGLHFFNPVPLMPLVEVIRGPATSD 160
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527 468 QVILDLMAVGKAIKKVPVVVGNCIGFAVNRTFFPY-SQAAHMLANLGVDLFRIDSVIT-SFGLPLGPFQLGDLAGHGIGL 545
Cdd:COG1250 161 ETVATAVAFARRLGKTPVVVKDTPGFIVNRILVPYlNEAIRLLEEGVASPEDIDAAMRlGFGFPMGPFELADLVGLDTAL 240
                       250       260       270       280
                ....*....|....*....|....*....|....*....|.
gi 15235527 546 AVGPIYAKVYGDRMFR-SPMTELLLKSGRNGKINGRGYYIY 585
Cdd:COG1250 241 AVLEVLYEALGDPRYRpPPLLKKLVEAGRLGRKTGRGFYDY 281
3HCDH_N pfam02737
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda ...
311-490 3.99e-74

3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda crystallin.


Pssm-ID: 397037 [Multi-domain]  Cd Length: 180  Bit Score: 237.44  E-value: 3.99e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   311 KVAVIGGGLMGSGIATALLLSNIRVVLKEINSEFLMKGIKSVEANMKSLVSRGKLTQDKAGKALSLFKGVLDYTEFNDVD 390
Cdd:pfam02737   1 KVAVIGAGTMGAGIAQVFALAGLEVVLVDISEEALEKALERIESSLERLVEKGRITEEEVDAALARISFTTDLAAAVDAD 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   391 MVIEAVIENIQLKQNIFKEIEKVCSPHCILASNTSTIDLDVIGEKTNSKDRIVGAHFFSPAHLMPLLEIVRSKNTSAQVI 470
Cdd:pfam02737  81 LVIEAVPENLELKRKLFAELDAIAPPDAILATNTSSLSITELAAATKRPERFIGLHFFNPPPLMPLVEVVRGEKTSPETV 160
                         170       180
                  ....*....|....*....|
gi 15235527   471 LDLMAVGKAIKKVPVVVGNC 490
Cdd:pfam02737 161 ATTVELAKKIGKTPVVVKDT 180
PRK05808 PRK05808
3-hydroxybutyryl-CoA dehydrogenase; Validated
309-585 4.11e-63

3-hydroxybutyryl-CoA dehydrogenase; Validated


Pssm-ID: 180269 [Multi-domain]  Cd Length: 282  Bit Score: 211.75  E-value: 4.11e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  309 IKKVAVIGGGLMGSGIATALLLSNIRVVLKEINSEFLMKGIKSVEANMKSLVSRGKLTQDKAGKALSLFKGVLDYTEFND 388
Cdd:PRK05808   3 IQKIGVIGAGTMGNGIAQVCAVAGYDVVMVDISDAAVDRGLATITKSLDRLVKKGKMTEADKEAALARITGTTDLDDLKD 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  389 VDMVIEAVIENIQLKQNIFKEIEKVCSPHCILASNTSTIDLDVIGEKTNSKDRIVGAHFFSPAHLMPLLEIVRSKNTSAQ 468
Cdd:PRK05808  83 ADLVIEAATENMDLKKKIFAQLDEIAKPEAILATNTSSLSITELAAATKRPDKVIGMHFFNPVPVMKLVEIIRGLATSDA 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  469 VILDLMAVGKAIKKVPVVVGNCIGFAVNRTFFPY-SQAAHMLANLGVDLFRIDSVITsFGL--PLGPFQLGDLAGHGIGL 545
Cdd:PRK05808 163 THEAVEALAKKIGKTPVEVKNAPGFVVNRILIPMiNEAIFVLAEGVATAEDIDEGMK-LGCnhPIGPLALADLIGLDTCL 241
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 15235527  546 AVGPIYAKVYGDRMFR-SPMTELLLKSGRNGKINGRGYYIY 585
Cdd:PRK05808 242 AIMEVLYEGFGDSKYRpCPLLRKMVAAGWLGRKTGRGFYDY 282
PRK08268 PRK08268
3-hydroxy-acyl-CoA dehydrogenase; Validated
306-711 6.05e-61

3-hydroxy-acyl-CoA dehydrogenase; Validated


Pssm-ID: 236211 [Multi-domain]  Cd Length: 507  Bit Score: 213.17  E-value: 6.05e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  306 PRPIKKVAVIGGGLMGSGIATALLLSNIRVVLKEINSEFLMKGIKSVEANMKSLVSRGKLTQDKAGKALSLFKGVLDYTE 385
Cdd:PRK08268   4 LPSIATVAVIGAGAMGAGIAQVAAQAGHTVLLYDARAGAAAAARDGIAARLAKLVEKGKLTAEQADAALARLRPVEALAD 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  386 FNDVDMVIEAVIENIQLKQNIFKEIEKVCSPHCILASNTSTIDLDVIGEKTNSKDRIVGAHFFSPAHLMPLLEIVRSKNT 465
Cdd:PRK08268  84 LADCDLVVEAIVERLDVKQALFAQLEAIVSPDCILATNTSSLSITAIAAALKHPERVAGLHFFNPVPLMKLVEVVSGLAT 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  466 SAQVILDLMAVGKAIKKVPVVVGNCIGFAVNRTFFPYSQAAHMLANLGV-DLFRIDSVI-TSFGLPLGPFQLGDLAGHGI 543
Cdd:PRK08268 164 DPAVADALYALARAWGKTPVRAKDTPGFIVNRAARPYYTEALRVLEEGVaDPATIDAILrEAAGFRMGPFELMDLIGLDV 243
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  544 GLAVG-PIYAKVYGDRMFR-SPMTELLLKSGRNGKINGRGYYIYEKGSKPKPD---------PSVLSIV----------- 601
Cdd:PRK08268 244 NHAVMeSVYRQFYQEPRFRpSLIQQELVAAGRLGRKSGQGFYRYADGAKQPPAeaappaalpPVWVSADvegdlaalarl 323
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  602 ----------------------------------------------------EKSRKLTnIMPG---------------- 613
Cdd:PRK08268 324 lerlgatietgegpsadglvllaptggdtttaaaregldaarvvlidllldyAAAKRRT-LMAApatspaardaahalfq 402
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  614 --GKPISVTD-------KEIVEMIlfpvVNEACRVLDEGVvirAS--DLDIASVLGMSFPSyrgGIVFWADTVGPKYIYE 682
Cdd:PRK08268 403 qdGKAVSVIRdspgfvaQRTVAMI----VNEAADIAQQGI---ASpaDIDLAMRLGLNYPL---GPLAWGDRLGAARILR 472
                        490       500       510
                 ....*....|....*....|....*....|
gi 15235527  683 RLKKLSETYGS-FFKPSRYLEERAMNGMLL 711
Cdd:PRK08268 473 VLENLQALYGDpRYRPSPWLRRRAALGLSL 502
PLN02545 PLN02545
3-hydroxybutyryl-CoA dehydrogenase
309-593 6.35e-56

3-hydroxybutyryl-CoA dehydrogenase


Pssm-ID: 215300 [Multi-domain]  Cd Length: 295  Bit Score: 193.02  E-value: 6.35e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  309 IKKVAVIGGGLMGSGIATALLLSNIRVVLKEINSEFLMKGIKSVEANMKSLVSRGKLTQDKAGKALSLFKGVLDYTEFND 388
Cdd:PLN02545   4 IKKVGVVGAGQMGSGIAQLAAAAGMDVWLLDSDPAALSRGLDSISSSLARLVKKGKMSQEEADATLGRIRCTTNLEELRD 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  389 VDMVIEAVIENIQLKQNIFKEIEKVCSPHCILASNTSTIDLDVIGEKTNSKDRIVGAHFFSPAHLMPLLEIVRSKNTSAQ 468
Cdd:PLN02545  84 ADFIIEAIVESEDLKKKLFSELDRICKPSAILASNTSSISITRLASATQRPQQVIGMHFMNPPPIMKLVEIIRGADTSDE 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  469 VILDLMAVGKAIKKVPVVVGNCIGFAVNRTFFP-YSQAAHMLANlGVDLFR-ID-SVITSFGLPLGPFQLGDLAGHGIGL 545
Cdd:PLN02545 164 VFDATKALAERFGKTVVCSQDYPGFIVNRILMPmINEAFYALYT-GVASKEdIDtGMKLGTNHPMGPLHLADFIGLDTCL 242
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 15235527  546 AVGPIYAKVYGDRMFR-SPMTELLLKSGRNGKINGRGYYIYEKGSKPKP 593
Cdd:PLN02545 243 SIMKVLHEGLGDSKYRpCPLLVQYVDAGRLGRKSGRGVYHYDGKKRGDP 291
PRK09260 PRK09260
3-hydroxyacyl-CoA dehydrogenase;
309-588 2.08e-52

3-hydroxyacyl-CoA dehydrogenase;


Pssm-ID: 236434 [Multi-domain]  Cd Length: 288  Bit Score: 183.07  E-value: 2.08e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  309 IKKVAVIGGGLMGSGIATALLLSNIRVVLKEINSEFLMKGIKSVEANMKSLVSRGKLTQDKAGKALSLFKGVLDYTE-FN 387
Cdd:PRK09260   1 IEKLVVVGAGVMGRGIAYVFAVSGFQTTLVDIKQEQLESAQQEIASIFEQGVARGKLTEAARQAALARLSYSLDLKAaVA 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  388 DVDMVIEAVIENIQLKQNIFKEIEKVCSPHCILASNTSTIDLDVIGEKTNSKDRIVGAHFFSPAHLMPLLEIVRSKNTSA 467
Cdd:PRK09260  81 DADLVIEAVPEKLELKKAVFETADAHAPAECYIATNTSTMSPTEIASFTKRPERVIAMHFFNPVHKMKLVELIRGLETSD 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  468 QVILDLMAVGKAIKKVPVVVGNCIGFAVNR-TFFPYSQAAHMLANLGVDLFRIDSVIT-SFGLPLGPFQLGDLAGHGIGL 545
Cdd:PRK09260 161 ETVQVAKEVAEQMGKETVVVNEFPGFVTSRiSALVGNEAFYMLQEGVATAEDIDKAIRlGLNFPMGPLELGDLVGLDTRL 240
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 15235527  546 AVGPIYAKVYGDRMFRSPMTELLLKSGRNGKINGRGYYIYEKG 588
Cdd:PRK09260 241 NNLKYLHETLGEKYRPAPLLEKYVKAGRLGRKTGRGVYDYTNR 283
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
14-291 1.84e-51

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 179.44  E-value: 1.84e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   14 DGVAVITISNPPVNSLASPIISGLKEKFRDANQRNDVKAIVLIGNnGRF-SGGFDINVFQQVHKTGDLSLMPEVSvELVC 92
Cdd:PRK07658  10 DHVAVITLNHPPANALSSQVLHELSELLDQVEKDDNVRVVVIHGE-GRFfSAGADIKEFTSVTEAEQATELAQLG-QVTF 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   93 NLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMILLSKSISS 172
Cdd:PRK07658  88 ERVEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVGKAKALEMMLTSEPITG 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  173 EEGHKLGLIDALVPpgdvlstsrkwaldiaegrkpflqslhrtdkigslsEARaILKNSRQLAKKIAPNMPQH-HACIEV 251
Cdd:PRK07658 168 AEALKWGLVNGVFP------------------------------------EET-LLDDAKKLAKKIAGKSPATtRAVLEL 210
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 15235527  252 IEEGIIHGGYSGVLKEAEVFKQLVLSDTAKGLVHVFFAQR 291
Cdd:PRK07658 211 LQTTKSSSYYEGVKREAKIFGEVFTSEDAKEGVQAFLEKR 250
PRK07530 PRK07530
3-hydroxybutyryl-CoA dehydrogenase; Validated
308-593 2.05e-48

3-hydroxybutyryl-CoA dehydrogenase; Validated


Pssm-ID: 181018 [Multi-domain]  Cd Length: 292  Bit Score: 172.50  E-value: 2.05e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  308 PIKKVAVIGGGLMGSGIATALLLSNIRVVLKEINSEFLMKGIKSVEANMKSLVSRGKLTQDKAGKALSLFKGVLDYTEFN 387
Cdd:PRK07530   3 AIKKVGVIGAGQMGNGIAHVCALAGYDVLLNDVSADRLEAGLATINGNLARQVAKGKISEEARAAALARISTATDLEDLA 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  388 DVDMVIEAVIENIQLKQNIFKEIEKVCSPHCILASNTSTIDLDVIGEKTNSKDRIVGAHFFSPAHLMPLLEIVRSKNTSA 467
Cdd:PRK07530  83 DCDLVIEAATEDETVKRKIFAQLCPVLKPEAILATNTSSISITRLASATDRPERFIGIHFMNPVPVMKLVELIRGIATDE 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  468 QVILDLMAVGKAIKKVPVVVGNCIGFAVNRTFFPY-SQAAHMLANlGVDlfRIDSVITSFGL----PLGPFQLGDLAGHG 542
Cdd:PRK07530 163 ATFEAAKEFVTKLGKTITVAEDFPAFIVNRILLPMiNEAIYTLYE-GVG--SVEAIDTAMKLganhPMGPLELADFIGLD 239
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 15235527  543 IGLAVGPIYAKVYGDRMFRS-PmteLLLK---SGRNGKINGRGYYIYeKGSKPKP 593
Cdd:PRK07530 240 TCLSIMQVLHDGLADSKYRPcP---LLVKyveAGWLGRKTGRGFYDY-RGEVPVP 290
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
7-201 9.52e-47

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 164.27  E-value: 9.52e-47
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   7 VTMEVgNDGVAVITISNPP-VNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINVFQQVHKTGDLSLMPE 85
Cdd:cd06558   1 VLVER-DGGVATITLNRPEkRNALSLEMLDELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAALSDAGEEARAFI 79
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  86 VSVELVCNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMIL 165
Cdd:cd06558  80 RELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLL 159
                       170       180       190
                ....*....|....*....|....*....|....*.
gi 15235527 166 LSKSISSEEGHKLGLIDALVPPGDVLSTSRKWALDI 201
Cdd:cd06558 160 TGRRISAEEALELGLVDEVVPDEELLAAALELARRL 195
PRK07819 PRK07819
3-hydroxybutyryl-CoA dehydrogenase; Validated
308-585 3.88e-46

3-hydroxybutyryl-CoA dehydrogenase; Validated


Pssm-ID: 181133 [Multi-domain]  Cd Length: 286  Bit Score: 165.93  E-value: 3.88e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  308 PIKKVAVIGGGLMGSGIATALLLSNIRVVLKEINSEFLMKGIKSVEANMKSLVSRGKLTQDKAGKALSLFKGVLDYTEFN 387
Cdd:PRK07819   4 AIQRVGVVGAGQMGAGIAEVCARAGVDVLVFETTEELATAGRNRIEKSLERAVSRGKLTERERDAALARLRFTTDLGDFA 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  388 DVDMVIEAVIENIQLKQNIFKEIEKVCS-PHCILASNTSTIDLDVIGEKTNSKDRIVGAHFFSPAHLMPLLEIVRSKNTS 466
Cdd:PRK07819  84 DRQLVIEAVVEDEAVKTEIFAELDKVVTdPDAVLASNTSSIPIMKLAAATKRPGRVLGLHFFNPVPVLPLVELVPTLVTS 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  467 AQVILDLMA-VGKAIKKVPVVVGNCIGFAVNRTFFPYSQAAHMLANLGV----DlfrID-SVITSFGLPLGPFQLGDLAG 540
Cdd:PRK07819 164 EATVARAEEfASDVLGKQVVRAQDRSGFVVNALLVPYLLSAIRMVESGFataeD---IDkAMVLGCAHPMGPLRLSDLVG 240
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 15235527  541 HGIGLAVGPIYAKVYGDRMFRSPmtELLLK---SGRNGKINGRGYYIY 585
Cdd:PRK07819 241 LDTVKAIADSMYEEFKEPLYAPP--PLLLRmveAGLLGKKSGRGFYTY 286
PRK06035 PRK06035
3-hydroxyacyl-CoA dehydrogenase; Validated
309-565 1.16e-45

3-hydroxyacyl-CoA dehydrogenase; Validated


Pssm-ID: 180361 [Multi-domain]  Cd Length: 291  Bit Score: 164.66  E-value: 1.16e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  309 IKKVAVIGGGLMGSGIATALLLSNIRVVLKEINSEFLMKGIKSVEAN---MKSLVSRGKLTQDKAGKALSLFKGVLDYTE 385
Cdd:PRK06035   3 IKVIGVVGSGVMGQGIAQVFARTGYDVTIVDVSEEILKNAMELIESGpygLRNLVEKGKMSEDEAKAIMARIRTSTSYES 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  386 FNDVDMVIEAVIENIQLKQNIFKEIEKVCSPHCILASNTSTIDLDVIGEKTNSKDRIVGAHFFSPAHLMPLLEIVRSKNT 465
Cdd:PRK06035  83 LSDADFIVEAVPEKLDLKRKVFAELERNVSPETIIASNTSGIMIAEIATALERKDRFIGMHWFNPAPVMKLIEVVRAALT 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  466 SAQVILDLMAVGKAIKKVPVVVGNCIGFAVNRTFFPYSQAAHMLANLGVDLFR-IDSVIT-SFGLPLGPFQLGDLAGHGI 543
Cdd:PRK06035 163 SEETFNTTVELSKKIGKIPIEVADVPGFFTTRFIEGWLLEAIRSFEIGIATIKdIDEMCKlAFGFPMGPFELMDIIGIDT 242
                        250       260
                 ....*....|....*....|..
gi 15235527  544 GLAVGPIYAKVYGDRMFRSPMT 565
Cdd:PRK06035 243 VYHIAEYLYEETGDPQFIPPNS 264
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
7-204 2.38e-45

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 162.26  E-value: 2.38e-45
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   7 VTMEVgNDGVAVITISNP-PVNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINVFQQVHKTGDLSLMPE 85
Cdd:COG1024   1 VLVER-EGGVATITLNRPeKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAAAADPEEARAFAR 79
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  86 vSVELVCNLMEDSRKPVVAAVeglalgggleLAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMIL 165
Cdd:COG1024  80 -GLQRLFRALRRLPKPVIAAVngaalgggleLALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLL 158
                       170       180       190
                ....*....|....*....|....*....|....*....
gi 15235527 166 LSKSISSEEGHKLGLIDALVPPGDVLSTSRKWALDIAEG 204
Cdd:COG1024 159 TGRRIDAEEALELGLVNRVVPDDELLAAALALAARLAAG 197
PRK06130 PRK06130
3-hydroxybutyryl-CoA dehydrogenase; Validated
308-607 1.30e-44

3-hydroxybutyryl-CoA dehydrogenase; Validated


Pssm-ID: 235707 [Multi-domain]  Cd Length: 311  Bit Score: 162.25  E-value: 1.30e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  308 PIKKVAVIGGGLMGSGIATALLLSNIRVVLKEINSEFLMKGIKSVEanmkslVSRGKLtqDKAGKALSLfKGVLDYTE-- 385
Cdd:PRK06130   3 PIQNLAIIGAGTMGSGIAALFARKGLQVVLIDVMEGALERARGVIE------RALGVY--APLGIASAG-MGRIRMEAgl 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  386 ---FNDVDMVIEAVIENIQLKQNIFKEIEKVCSPHCILASNTSTIDLDVIGEKTNSKDRIVGAHFFSPAHLMPLLEIVRS 462
Cdd:PRK06130  74 aaaVSGADLVIEAVPEKLELKRDVFARLDGLCDPDTIFATNTSGLPITAIAQAVTRPERFVGTHFFTPADVIPLVEVVRG 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  463 KNTSAQVILDLMAVGKAIKKVPVVVGNCI-GFAVNRTFFPYSQAAHMLANLGV-DLFRIDSVIT-SFGLPL---GPFQLG 536
Cdd:PRK06130 154 DKTSPQTVATTMALLRSIGKRPVLVKKDIpGFIANRIQHALAREAISLLEKGVaSAEDIDEVVKwSLGIRLaltGPLEQR 233
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15235527  537 DLAGHGIGLAVGPIYAKVYGDRMFRSPMTELLLKSGRNGKINGRGYYIYEkgskPKPDPSVLSivEKSRKL 607
Cdd:PRK06130 234 DMNGLDVHLAVASYLYQDLENRTTPSPLLEEKVEAGELGAKSGQGFYAWP----PERREEVLA--DKSAAL 298
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
14-204 6.39e-37

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 139.23  E-value: 6.39e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   14 DGVAVITISNP-PVNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINVFQQVHKTGDLSLMPevsVELVC 92
Cdd:PRK06688  13 DGVLTITINRPdKKNALTAAMYQALADALEAAATDPAVRVVVLTGAGRAFSAGGDIKDFPKAPPKPPDELAP---VNRFL 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   93 NLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMILLSKSISS 172
Cdd:PRK06688  90 RAIAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRLIGRARAAEMLLLGEPLSA 169
                        170       180       190
                 ....*....|....*....|....*....|..
gi 15235527  173 EEGHKLGLIDALVPPGDVLSTSRKWALDIAEG 204
Cdd:PRK06688 170 EEALRIGLVNRVVPAAELDAEADAQAAKLAAG 201
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
12-204 1.67e-32

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 126.32  E-value: 1.67e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527    12 GNDGVAVITISNP-PVNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINV-------FQQVHKTGDLSLM 83
Cdd:pfam00378   2 INAGVAVITLNRPeAVNALSAELITELIQALEKLRTDPSVRAVVLTGGDKAFCAGADLKEmygegpaHQALYRENVLDLW 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527    84 PEVSvelvcnlmeDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDM 163
Cdd:pfam00378  82 TLLY---------TCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEM 152
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 15235527   164 ILLSKSISSEEGHKLGLIDALVPPGDVLSTSRKWALDIAEG 204
Cdd:pfam00378 153 LLLGRRISAQEALKWGLVDKVVPEDQLLDEARELAEKLAEK 193
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
7-203 8.82e-30

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 118.68  E-value: 8.82e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527    7 VTMEVGNDGVAVITISNP-PVNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGR-FSGGFDINVF-----QQVHKTgd 79
Cdd:PRK07657   5 ISVDYVTPHVVKITLNRPrAANALSLALLEELQNILTQINEEANVRVVILTGAGEKaFCAGADLKERagmneEQVRHA-- 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   80 LSLMPEVSvelvcNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAK 159
Cdd:PRK07657  83 VSLIRTTM-----EMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGR 157
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 15235527  160 ATDMILLSKSISSEEGHKLGLIDALVPPGDVLSTsrkwALDIAE 203
Cdd:PRK07657 158 AKELIYTGRRISAQEAKEIGLVEFVVPAHLLEEK----AIEIAE 197
PRK08293 PRK08293
3-hydroxyacyl-CoA dehydrogenase;
309-585 6.59e-29

3-hydroxyacyl-CoA dehydrogenase;


Pssm-ID: 181359 [Multi-domain]  Cd Length: 287  Bit Score: 116.96  E-value: 6.59e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  309 IKKVAVIGGGLMGSGIATALLLSNIRVVLKEINSEFLMKGIKSVEANMKSLVSRGKLTQ-DKAGKALSLFKGVLDYTE-F 386
Cdd:PRK08293   3 IKNVTVAGAGVLGSQIAFQTAFHGFDVTIYDISDEALEKAKERIAKLADRYVRDLEATKeAPAEAALNRITLTTDLAEaV 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  387 NDVDMVIEAVIENIQLKQNIFKEIEKVCSPHCILASNTSTIDLDVIGEKTNSKDRIVGAHFFSPAHLMPLLEIVRSKNTS 466
Cdd:PRK08293  83 KDADLVIEAVPEDPEIKGDFYEELAKVAPEKTIFATNSSTLLPSQFAEATGRPEKFLALHFANEIWKNNTAEIMGHPGTD 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  467 AQVILDLMAVGKAIKKVPVVV-GNCIGFAVNRTFFPYSQAAHMLANLGV-DLFRID-SVITSFGLPLGPFQLGDLAGHGI 543
Cdd:PRK08293 163 PEVFDTVVAFAKAIGMVPIVLkKEQPGYILNSLLVPFLSAALALWAKGVaDPETIDkTWMIATGAPMGPFGILDIVGLDT 242
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 15235527  544 GLAVGPIYAKVYGDrmFRSPMTELLLK----SGRNGKINGRGYYIY 585
Cdd:PRK08293 243 AYNITSNWAEATDD--ENAKKAAALLKeyidKGKLGVATGEGFYNY 286
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
7-202 8.72e-28

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 112.84  E-value: 8.72e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527    7 VTMEVGNDGVAVITISNPPV-NSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINVFQQvhkTGDLSLMPE 85
Cdd:PRK08138   9 VLLERPADGVALLRLNRPEArNALNMEVRQQLAEHFTELSEDPDIRAIVLTGGEKVFAAGADIKEFAT---AGAIEMYLR 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   86 vSVELVCNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMIL 165
Cdd:PRK08138  86 -HTERYWEAIAQCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQRLVRAVGKFKAMRMAL 164
                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 15235527  166 LSKSISSEEGHKLGLIDALVPPGDVLSTSRKWALDIA 202
Cdd:PRK08138 165 TGCMVPAPEALAIGLVSEVVEDEQTLPRALELAREIA 201
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
14-203 1.19e-27

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 112.44  E-value: 1.19e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   14 DGVAVITISNP-PVNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINVFQqvhktgDLSLMPEVSVELVC 92
Cdd:PRK05862  12 GRVGLITLNRPkALNALNDALMDELGAALAAFDADEGIGAIVITGSEKAFAAGADIKEMA------DLSFMDVYKGDYIT 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   93 NL--MEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMILLSKSI 170
Cdd:PRK05862  86 NWekVARIRKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSQRLTRAVGKAKAMDLCLTGRMM 165
                        170       180       190
                 ....*....|....*....|....*....|...
gi 15235527  171 SSEEGHKLGLIDALVPPGDVLSTSRKWALDIAE 203
Cdd:PRK05862 166 DAAEAERAGLVSRVVPADKLLDEALAAATTIAS 198
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
9-202 4.77e-27

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 110.99  E-value: 4.77e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527    9 MEVGN------DGVAVITISNP-PVNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGR-FSGGFDInvfqqvhktgdl 80
Cdd:PRK05809   1 MELKNvilekeGHIAVVTINRPkALNALNSETLKELDTVLDDIENDDNVYAVILTGAGEKaFVAGADI------------ 68
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   81 SLMPEVSVE----------LVCNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQR 150
Cdd:PRK05809  69 SEMKDLNEEegrkfgllgnKVFRKLENLDKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQR 148
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 15235527  151 LPRLVGLAKATDMILLSKSISSEEGHKLGLIDALVPPGDVLSTSRKWALDIA 202
Cdd:PRK05809 149 LARIVGPGKAKELIYTGDMINAEEALRIGLVNKVVEPEKLMEEAKALANKIA 200
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
14-202 3.89e-25

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 105.23  E-value: 3.89e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   14 DGVAVITISNPP-VNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGR-FSGGFDINVFqqvhkTGDLSLMPEVSV--- 88
Cdd:PRK05980  11 DGIALLTLNRPEkLNALNYALIDRLLARLDAIEVDESVRAVILTGAGDRaFSAGADIHEF-----SASVAAGADVALrdf 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   89 ----ELVCNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMI 164
Cdd:PRK05980  86 vrrgQAMTARLEAFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGGTQRLPRLAGRKRALELL 165
                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 15235527  165 LLSKSISSEEGHKLGLIDALVPPGDVLSTSRKWALDIA 202
Cdd:PRK05980 166 LTGDAFSAERALEIGLVNAVVPHEELLPAARALARRII 203
PRK06129 PRK06129
3-hydroxyacyl-CoA dehydrogenase; Validated
308-569 6.18e-25

3-hydroxyacyl-CoA dehydrogenase; Validated


Pssm-ID: 235706 [Multi-domain]  Cd Length: 308  Bit Score: 105.90  E-value: 6.18e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  308 PIKKVAVIGGGLMGSGIATALLLSNIRVVLKEINSEFLMKGIKSVEANMKSLVSRGKLTQDKAGKALSLFKGVLDYTE-F 386
Cdd:PRK06129   1 PMGSVAIIGAGLIGRAWAIVFARAGHEVRLWDADPAAAAAAPAYIAGRLEDLAAFDLLDGEAPDAVLARIRVTDSLADaV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  387 NDVDMVIEAVIENIQLKQNIFKEIEKVCSPHCILASNTSTIDLDVIGEKTNSKDRIVGAHFFSPAHLMPLLEIVRSKNTS 466
Cdd:PRK06129  81 ADADYVQESAPENLELKRALFAELDALAPPHAILASSTSALLASAFTEHLAGRERCLVAHPINPPYLIPVVEVVPAPWTA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  467 AQVILDLMAVGKAIKKVPVVVGNCI-GFAVNRTffpysQAA------HMLAN--LGVDlfRIDSVITSfGLPL-----GP 532
Cdd:PRK06129 161 PATLARAEALYRAAGQSPVRLRREIdGFVLNRL-----QGAllreafRLVADgvASVD--DIDAVIRD-GLGLrwsfmGP 232
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 15235527  533 FQLGDLAGHGiGLA-----VGPIYAKVYGDRMFRSPMTELLL 569
Cdd:PRK06129 233 FETIDLNAPG-GVAdyaqrYGPMYRRMAAERGQPVPWDGELV 273
3HCDH pfam00725
3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; This family also includes lambda ...
492-585 4.58e-24

3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; This family also includes lambda crystallin. Some proteins include two copies of this domain.


Pssm-ID: 395588 [Multi-domain]  Cd Length: 97  Bit Score: 96.90  E-value: 4.58e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   492 GFAVNRTFFPYSQAAHMLANLGV-DLFRIDSVIT-SFGLPLGPFQLGDLAGHGIGLAVGPIYAKVYGDRMFR-SPMTELL 568
Cdd:pfam00725   1 GFVVNRLLAPYLNEAIRLVEEGVaTPEDIDAAMRlGLGLPMGPFELSDLVGLDVGYHILEVLAEEFGDRAYRpPPLLEKL 80
                          90
                  ....*....|....*..
gi 15235527   569 LKSGRNGKINGRGYYIY 585
Cdd:pfam00725  81 VEAGRLGRKTGKGFYKY 97
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
16-198 9.82e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 101.15  E-value: 9.82e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   16 VAVITISNPPVNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRF-SGGFDINVFQQvhktGDLSLMPEVS------V 88
Cdd:PRK09076  13 VAILTLNNPPANTWTADSLQALKQLVLELNADKDVYALVITGDGEKFfSAGADLNLFAD----GDKAVAREMArrfgeaF 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   89 ELVCNLmedsRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMILLSK 168
Cdd:PRK09076  89 EALSAF----RGVSIAAINGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCAGGTQNLPWLVGEGWAKRMILCGE 164
                        170       180       190
                 ....*....|....*....|....*....|
gi 15235527  169 SISSEEGHKLGLIDALVPPGDVLSTSRKWA 198
Cdd:PRK09076 165 RVDAATALRIGLVEEVVEKGEAREAALALA 194
PRK08269 PRK08269
3-hydroxybutyryl-CoA dehydrogenase; Validated
320-585 1.78e-23

3-hydroxybutyryl-CoA dehydrogenase; Validated


Pssm-ID: 181340 [Multi-domain]  Cd Length: 314  Bit Score: 101.67  E-value: 1.78e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  320 MGSGIATALLLSNIRVVLKEIN-------SEFLMKGIKSVEANMKSLVSRGKLTQDKAGKALslfkGVLDY-------TE 385
Cdd:PRK08269   1 MGQGIALAFAFAGHDVTLIDFKprdaagwRALDAEARAEIERTLAALVALGRIDAAQADAVL----ARIAVvardgaaDA 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  386 FNDVDMVIEAVIENIQLKQNIFKEIEKVCSPHCILASNTSTIDLDVIGEKTNSKDRIVGAHFFSPAHLMPLLEIVRSKNT 465
Cdd:PRK08269  77 LADADLVFEAVPEVLDAKREALRWLGRHVDADAIIASTTSTFLVTDLQRHVAHPERFLNAHWLNPAYLMPLVEVSPSDAT 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  466 SAQVILDLMAVGKAIKKVPVVVGNCIGFAVNR-TFFPYSQAAHMLANLGVDLFRIDSVI-TSFGLP---LGPFQLGDLAG 540
Cdd:PRK08269 157 DPAVVDRLAALLERIGKVPVVCGPSPGYIVPRiQALAMNEAARMVEEGVASAEDIDKAIrTGFGLRfavLGLLEFIDWGG 236
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 15235527  541 HGIGLAVGPIYAKVYGDRMFRSP-MTELLLKSGRNGKINGRGYYIY 585
Cdd:PRK08269 237 CDILYYASRYLAGEIGPDRFAPPaIVVRNMEEGRDGLRTGAGFYDY 282
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
14-203 4.31e-23

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 99.07  E-value: 4.31e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   14 DGVAVITISNPPV-NSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINVFQQvhktGDLSLMpevsvelvc 92
Cdd:PRK09674  10 QRVLLLTLNRPEArNALNNALLTQLVNELEAAATDTSIGVCVITGNARFFAAGADLNEMAE----KDLAAT--------- 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   93 nlMEDSR-----------KPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKAT 161
Cdd:PRK09674  77 --LNDPRpqlwqrlqafnKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRLIRSVGKSLAS 154
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 15235527  162 DMILLSKSISSEEGHKLGLIDALVPPGDVLSTSRKWALDIAE 203
Cdd:PRK09674 155 QMVLTGESITAQQAQQAGLVSEVFPPELTLERALQLASKIAR 196
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
14-203 4.91e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 98.96  E-value: 4.91e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   14 DGVAVITISNPPV-NSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGR-FSGGFDINvfQQ-------VHKTGDLSLMP 84
Cdd:PRK06494  12 GHVTIVTLNRPEVmNALHLDAHFELEEVFDDFAADPEQWVAIVTGAGDKaFSAGNDLK--EQaaggkrgWPESGFGGLTS 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   85 EVsvelvcnlmeDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMI 164
Cdd:PRK06494  90 RF----------DLDKPIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPRQIGLKRAMGMI 159
                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 15235527  165 LLSKSISSEEGHKLGLIDALVPPGDVLSTSRKWALDIAE 203
Cdd:PRK06494 160 LTGRRVTAREGLELGFVNEVVPAGELLAAAERWADDILA 198
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
14-204 2.82e-21

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 94.26  E-value: 2.82e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   14 DGVAVITISNPP-VNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDinVFQQVHKTGDLSlMPEV------ 86
Cdd:PRK08258  25 DGVATITLNRPErKNPLTFESYAELRDLFRELVYADDVKAVVLTGAGGNFCSGGD--VHEIIGPLTKMD-MPELlaftrm 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   87 SVELVcNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPG-FGGTQRLPRLVGLAKATDMIL 165
Cdd:PRK08258 102 TGDLV-KAMRACPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAFLFTRVGLAGAdMGACALLPRIIGQGRASELLY 180
                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 15235527  166 LSKSISSEEGHKLGLIDALVPPGDVLSTSRKWALDIAEG 204
Cdd:PRK08258 181 TGRSMSAEEGERWGFFNRLVEPEELLAEAQALARRLAAG 219
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
14-203 2.89e-21

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 93.90  E-value: 2.89e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   14 DGVAVITISNPPV-NSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINVFQQvhktGDlslMPEVSVELVC 92
Cdd:PRK08252  11 GRVLIITINRPEArNAVNAAVAQGLAAALDELDADPDLSVGILTGAGGTFCAGMDLKAFAR----GE---RPSIPGRGFG 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   93 NLMEDS-RKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMILLSKSIS 171
Cdd:PRK08252  84 GLTERPpRKPLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAGGGLLRLPRRIPYHIAMELALTGDMLT 163
                        170       180       190
                 ....*....|....*....|....*....|..
gi 15235527  172 SEEGHKLGLIDALVPPGDVLSTSRKWALDIAE 203
Cdd:PRK08252 164 AERAHELGLVNRLTEPGQALDAALELAERIAA 195
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
13-203 6.01e-21

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 92.77  E-value: 6.01e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   13 NDGVAVITISNPPV-NSLASPIISGLKEKFRDANqrNDVKAIVLIGNNGRFSGGFDINVFQQVHKTGDL--SLM-PEVsv 88
Cdd:PRK08150   9 DGGVATIGLNRPAKrNALNDGLIAALRAAFARLP--EGVRAVVLHGEGDHFCAGLDLSELRERDAGEGMhhSRRwHRV-- 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   89 elvCNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMILLSK 168
Cdd:PRK08150  85 ---FDKIQYGRVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLIGVARMTDMMLTGR 161
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 15235527  169 SISSEEGHKLGLIDALVPPGDVLSTSRKWALDIAE 203
Cdd:PRK08150 162 VYDAQEGERLGLAQYLVPAGEALDKAMELARRIAQ 196
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
14-202 1.51e-20

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 91.68  E-value: 1.51e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   14 DGVAVITISNPPVNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINVFQQVHKT-GDLSLMPEVSVElVC 92
Cdd:PRK06495  12 DHVAVVTLDNPPVNALSRELRDELIAVFDEISERPDVRVVVLTGAGKVFCAGADLKGRPDVIKGpGDLRAHNRRTRE-CF 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   93 NLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIpgfGGTQRLPRLVGLAKATDMILLSKSISS 172
Cdd:PRK06495  91 HAIRECAKPVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGLA---GGGKHAMRLFGHSLTRRMMLTGYRVPA 167
                        170       180       190
                 ....*....|....*....|....*....|
gi 15235527  173 EEGHKLGLIDALVPPGDVLSTSRKWALDIA 202
Cdd:PRK06495 168 AELYRRGVIEACLPPEELMPEAMEIAREIA 197
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
4-204 1.39e-19

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 87.97  E-value: 1.39e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527    4 KIGVTMEVGNDGVAVITISNPPVNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINVFQQV--HKTGDLS 81
Cdd:PRK05869   6 NVVVSDGSQDAGLATLLLSRPPTNALTRQVYREIVAAANELGRRDDVAAVILYGGHEIFSAGDDMPELRTLsaQEADTAA 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   82 LMPEVSVELVCNLmedsRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKAT 161
Cdd:PRK05869  86 RVRQQAVDAVAAI----PKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLAPSGDGMARLTRAAGPSRAK 161
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 15235527  162 DMILLSKSISSEEGHKLGLIDALVPPGDVLSTSRKWALDIAEG 204
Cdd:PRK05869 162 ELVFSGRFFDAEEALALGLIDEMVAPDDVYDAAAAWARRFLDG 204
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
14-203 2.43e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 88.61  E-value: 2.43e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   14 DGVAVITISNPP-VNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGR-FSGGFDINVFQQVHKTGDLSLMPEVSVELV 91
Cdd:PRK06127  19 GGLGRITFNNPArHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGEKaFVSGADISQFEESRSDAEAVAAYEQAVEAA 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   92 CNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMILLSKSIS 171
Cdd:PRK06127  99 QAALADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGYGYDGVKNLVDLVGPSAAKDLFYTARRFD 178
                        170       180       190
                 ....*....|....*....|....*....|..
gi 15235527  172 SEEGHKLGLIDALVPPGDVLSTSRKWALDIAE 203
Cdd:PRK06127 179 AAEALRIGLVHRVTAADDLETALADYAATIAG 210
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
13-207 2.93e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 88.91  E-value: 2.93e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   13 NDGVAVITISNPP-VNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDI----NVFQQVHKTGDLSLMPEVS 87
Cdd:PRK08260  11 ADGIATITLNRPDkLNAFTVTMARELIEAFDAADADDAVRAVIVTGAGRAFCAGADLsaggNTFDLDAPRTPVEADEEDR 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   88 VELVCNL-----------MEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVG 156
Cdd:PRK08260  91 ADPSDDGvrdgggrvtlrIFDSLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAASSWFLPRLVG 170
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 15235527  157 LAKATDMILLSKSISSEEGHKLGLIDALVPPGDVLSTSRKWALDIAEGRKP 207
Cdd:PRK08260 171 LQTALEWVYSGRVFDAQEALDGGLVRSVHPPDELLPAARALAREIADNTSP 221
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
1-207 3.61e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 88.22  E-value: 3.61e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527    1 MAKKIGVTMEVGNDGVAVITISNPP-VNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINVFQQVH---K 76
Cdd:PRK06210   1 DMAYDAVLYEVADSGVAVITLNRPDrLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGAGRGFCAGADMGELQTIDpsdG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   77 TGDLSLMPEV-----SVELVCNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRL 151
Cdd:PRK06210  81 RRDTDVRPFVgnrrpDYQTRYHFLTALRKPVIAAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHGISWIL 160
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 15235527  152 PRLVGLAKATDMILLSKSISSEEGHKLGLIDALVPPGDVLSTSRKWALDIAEGRKP 207
Cdd:PRK06210 161 PRLVGHANALDLLLSARTFYAEEALRLGLVNRVVPPDELMERTLAYAEDLARNVSP 216
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
14-189 8.29e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 86.63  E-value: 8.29e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   14 DGVAVITISNP-PVNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGR-FSGGFDINvfqqvhktgDLSLMPEVSVEL- 90
Cdd:PRK06143  15 RGVATLTIRNAgSLNILGTPVILALTQALRWLAADPDVRVLVLRGAGEKaFIGGADIK---------EMATLDQASAEAf 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   91 ------VCNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGvIPGFGGTQRLPRLVGLAKATDMI 164
Cdd:PRK06143  86 isrlrdLCDAVRHFPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVG-IPSVIHAALLPRLIGWARTRWLL 164
                        170       180
                 ....*....|....*....|....*
gi 15235527  165 LLSKSISSEEGHKLGLIDALVPPGD 189
Cdd:PRK06143 165 LTGETIDAAQALAWGLVDRVVPLAE 189
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
13-227 9.93e-19

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 86.49  E-value: 9.93e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   13 NDGVAVITISNPPV-NSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINVFQ-----QVHKTGDlslmpev 86
Cdd:PRK08259  10 NGPVTTVILNRPEVrNAVDGPTAAALADAFRAFDADDAASVAVLWGAGGTFCAGADLKAVGtgrgnRLHPSGD------- 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   87 svelvcNLMEDSR----KPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATD 162
Cdd:PRK08259  83 ------GPMGPSRmrlsKPVIAAVSGYAVAGGLELALWCDLRVAEEDAVFGVFCRRWGVPLIDGGTVRLPRLIGHSRAMD 156
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  163 MILLSKSISSEEGHKLGLIDALVPPGDVLSTSRKWALDIAEgrkpFLQSLHRTDKIG-----SLSEARAI 227
Cdd:PRK08259 157 LILTGRPVDADEALAIGLANRVVPKGQARAAAEELAAELAA----FPQTCLRADRLSaleqwGLPEEAAL 222
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
13-188 1.59e-18

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 85.81  E-value: 1.59e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   13 NDGVAVITISNPPV-NSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGR-FSGGFDINVFQQVhKTGDLSLMPEVSVEL 90
Cdd:PRK06144  15 RGGIARITFNRPAArNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGDKaFVAGTDIAQFRAF-STAEDAVAYERRIDR 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   91 VCNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLP-ELTLGVIPGFGGTQRLPRLVGLAKATDMILLSKS 169
Cdd:PRK06144  94 VLGALEQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGFPiARTLGNCLSMSNLARLVALLGAARVKDMLFTARL 173
                        170
                 ....*....|....*....
gi 15235527  170 ISSEEGHKLGLIDALVPPG 188
Cdd:PRK06144 174 LEAEEALAAGLVNEVVEDA 192
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
14-204 4.15e-18

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 84.66  E-value: 4.15e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   14 DGVAVITISNPPV-NSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINVFQqvhktGDLSLMPEV---SVE 89
Cdd:PRK07511  11 GSTLVLTLSNPGArNALHPDMYAAGIEALNTAERDPSIRAVVLTGAGGFFCAGGNLNRLL-----ENRAKPPSVqaaSID 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   90 LVCNLME---DSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMILL 166
Cdd:PRK07511  86 GLHDWIRairAFPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLARALPRQLATELLLE 165
                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 15235527  167 SKSISSEEGHKLGLIDALVPPGDVLSTSRKWALDIAEG 204
Cdd:PRK07511 166 GKPISAERLHALGVVNRLAEPGQALAEALALADQLAAG 203
PLN02888 PLN02888
enoyl-CoA hydratase
15-202 2.95e-17

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 82.49  E-value: 2.95e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   15 GVAVITISNP-PVNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINVFQQVHKtGDLSLmpeVSVELVCN 93
Cdd:PLN02888  19 GIATITINRPkALNALTRPMMVELAAAFKRLDEDDSVKVIILTGSGRAFCSGVDLTAAEEVFK-GDVKD---VETDPVAQ 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   94 lMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMILLSKSISSE 173
Cdd:PLN02888  95 -MERCRKPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLSRIIGANRAREVSLTAMPLTAE 173
                        170       180
                 ....*....|....*....|....*....
gi 15235527  174 EGHKLGLIDALVPPGDVLSTSRKWALDIA 202
Cdd:PLN02888 174 TAERWGLVNHVVEESELLKKAREVAEAII 202
PLN02600 PLN02600
enoyl-CoA hydratase
13-203 4.14e-17

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 81.77  E-value: 4.14e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   13 NDGVAVITISNPPV-NSLASPIISGLKEKFrDANQRNDVKAIVLIGNN--GRFSGGFDInvfqQVHKTGDLSLMPEV--S 87
Cdd:PLN02600   2 DSGIVELRLDRPEAkNAIGKEMLRGLRSAF-EKIQADASARVVMLRSSvpGVFCAGADL----KERRKMSPSEVQKFvnS 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   88 VELVCNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMILLS 167
Cdd:PLN02600  77 LRSTFSSLEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTG 156
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 15235527  168 KSISSEEGHKLGLIDALVPPGDvlstSRKWALDIAE 203
Cdd:PLN02600 157 RRIGAREAASMGLVNYCVPAGE----AYEKALELAQ 188
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
14-212 2.48e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 79.63  E-value: 2.48e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   14 DGVAVITISNPPV-NSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDI-----NVFQQVHKTGDLSLMPEVs 87
Cdd:PRK06190  12 DRVRTLTLNRPEArNALSAALRRALFAALAEADADDDVDVVVLTGADPAFCAGLDLkelggDGSAYGAQDALPNPSPAW- 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   88 velvcnlmEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMILLS 167
Cdd:PRK06190  91 --------PAMRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLSVRLPQKVGIGRARRMSLTG 162
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 15235527  168 KSISSEEGHKLGLIDALVPPGDVLSTSRKWALDIAEGRKPFLQSL 212
Cdd:PRK06190 163 DFLDAADALRAGLVTEVVPHDELLPRARRLAASIAGNNPAAVRAL 207
PRK07531 PRK07531
carnitine 3-dehydrogenase;
308-540 2.73e-16

carnitine 3-dehydrogenase;


Pssm-ID: 236044 [Multi-domain]  Cd Length: 495  Bit Score: 82.48  E-value: 2.73e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  308 PIKKVAVIGGGLMGSGIATALLLSNIRVVLKEINSEFLMKgIKSVEAN---------MKSLVSRGKLT-QDKAGKALSlf 377
Cdd:PRK07531   3 MIMKAACIGGGVIGGGWAARFLLAGIDVAVFDPHPEAERI-IGEVLANaerayamltDAPLPPEGRLTfCASLAEAVA-- 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  378 kgvldytefnDVDMVIEAVIENIQLKQNIFKEIEKVCSPHCILASNTSTIDLDVIGEKTNSKDRIVGAHFFSPAHLMPLL 457
Cdd:PRK07531  80 ----------GADWIQESVPERLDLKRRVLAEIDAAARPDALIGSSTSGFLPSDLQEGMTHPERLFVAHPYNPVYLLPLV 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  458 EIVRSKNTSAQVILDLMAVGKAIKKVPVVVGNCI-GFAVNRTFFPYSQAAHMLANLGV-DLFRIDSVIT-SFGL---PLG 531
Cdd:PRK07531 150 ELVGGGKTSPETIRRAKEILREIGMKPVHIAKEIdAFVGDRLLEALWREALWLVKDGIaTTEEIDDVIRySFGLrwaQMG 229

                 ....*....
gi 15235527  532 PFQLGDLAG 540
Cdd:PRK07531 230 LFETYRIAG 238
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
18-203 1.77e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 77.06  E-value: 1.77e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   18 VITISNPPV-NSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINVFQQVH-------KTGDLSLMPevsve 89
Cdd:PRK07799  17 IVTMNRPEArNALSTEMLRIMVDAWDRVDNDPDIRSCILTGAGGAFCAGMDLKAATKKPpgdsfkdGSYDPSRID----- 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   90 lvcNLMEDSR--KPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMILLS 167
Cdd:PRK07799  92 ---ALLKGRRltKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFPMGGSAVRLVRQIPYTVACDLLLTG 168
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 15235527  168 KSISSEEGHKLGLIDALVPPGDVLSTsrkwALDIAE 203
Cdd:PRK07799 169 RHITAAEAKEIGLIGHVVPDGQALDK----ALELAE 200
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
13-204 1.90e-15

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 77.04  E-value: 1.90e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   13 NDGVAVITISNPPVNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGR-FSGGFDInvfqQVHKTGDlslMP--EVSVE 89
Cdd:PRK03580  10 NGSILEITLDRPKANAIDAKTSFAMGEVFLNFRDDPELRVAIITGAGEKfFSAGWDL----KAAAEGE---APdaDFGPG 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   90 LVCNLME--DSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMILLS 167
Cdd:PRK03580  83 GFAGLTEifDLDKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKRLPPAIANEMVMTG 162
                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 15235527  168 KSISSEEGHKLGLIDALVPPGDVLSTSRKWALDIAEG 204
Cdd:PRK03580 163 RRMDAEEALRWGIVNRVVPQAELMDRARELAQQLVNS 199
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
7-202 7.88e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 75.40  E-value: 7.88e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527    7 VTMEVgNDGVAVITISNP-PVNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDI----NVFQQVHKTGD-- 79
Cdd:PRK06142   8 FTVEL-ADHVAQVTLNRPgKGNAMNPAFWSELPEIFRWLDADPEVRAVVLSGSGKHFSYGIDLpamaGVFGQLGKDGLar 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   80 --LSLMPEV-SVELVCNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVG 156
Cdd:PRK06142  87 prTDLRREIlRLQAAINAVADCRKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVADVGSLQRLPRIIG 166
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 15235527  157 LAKATDMILLSKSISSEEGHKLGLIDALVPPGD-VLSTSRKWALDIA 202
Cdd:PRK06142 167 DGHLRELALTGRDIDAAEAEKIGLVNRVYDDADaLLAAAHATAREIA 213
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
15-215 3.99e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 73.33  E-value: 3.99e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   15 GVAVITISNPP-VNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINVFQQVHKTGDLSlMPEV---SVEL 90
Cdd:PRK05864  19 EIALITLNRPErMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGAGRGFSSGADHKSAGVVPHVEGLT-RPTYalrSMEL 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   91 VCNLMEDSRK---PVVAAVEGLALGGGLELAMACHARVAAPKAQL-------GLPELTLGVipgfggTQRLPRLVGLAKA 160
Cdd:PRK05864  98 LDDVILALRRlhqPVIAAVNGPAIGGGLCLALAADIRVASSSAYFraaginnGLTASELGL------SYLLPRAIGSSRA 171
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 15235527  161 TDMILLSKSISSEEGHKLGLIDALVPPGDVLSTSRKWALDIAEGRKPFLQSLHRT 215
Cdd:PRK05864 172 FEIMLTGRDVDAEEAERIGLVSRQVPDEQLLDTCYAIAARMAGFSRPGIELTKRT 226
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
6-203 6.08e-14

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 72.31  E-value: 6.08e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527    6 GVTMEVGNDGVAVITISNPPVNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINVFQqvHKTGDLSLmpe 85
Cdd:PRK07938   2 PITSTTPEPGIAEVTVDYPPVNALPSAGWFALADAITAAGADPDTRVVVLRAEGRGFNAGVDIKELQ--ATPGFTAL--- 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   86 VSVELVC----NLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIpgfGGTQRLPRLVGLAKAT 161
Cdd:PRK07938  77 IDANRGCfaafRAVYECAVPVIAAVHGFCLGGGIGLVGNADVIVASDDATFGLPEVDRGAL---GAATHLQRLVPQHLMR 153
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 15235527  162 DMILLSKSISSEEGHKLGLIDALVPPGDVLSTSRKWALDIAE 203
Cdd:PRK07938 154 ALFFTAATITAAELHHFGSVEEVVPRDQLDEAALEVARKIAA 195
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
7-204 6.42e-14

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 72.46  E-value: 6.42e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527    7 VTMEVgNDGVAVITISNPPVNSLASP-IISGLKEKFRD-ANQRNDVKAIVLIGNNGRFSGGFDINVFQQVHKTGDLSLMP 84
Cdd:PRK05981   6 VTLDF-DGGVAILTLDHPEVMNAVSIdMLGGLAEALDAiEDGKAEVRCLVLTGAGRGFCTGANLQGRGSGGRESDSGGDA 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   85 EVSVELVCN----LMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKA 160
Cdd:PRK05981  85 GAALETAYHpflrRLRNLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTWLLPRLVGKARA 164
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 15235527  161 TDMILLSKSISSEEGHKLGLIDALVPPGDVLSTSRKWALDIAEG 204
Cdd:PRK05981 165 MELSLLGEKLPAETALQWGLVNRVVDDAELMAEAMKLAHELANG 208
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
8-187 7.90e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 72.26  E-value: 7.90e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527    8 TMEVGNDG-VAVITISNPPV-NSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINVFQqvhKTGDLSLM-P 84
Cdd:PRK05995   5 TLEIEQRGqVATVTLNRPDVrNAFNETVIAELTAAFRALDADDSVRAVVLAGAGKAFCAGADLNWMK---KMAGYSDDeN 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   85 EVSVELVCNLMEDSR---KPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPgfggTQRLP---RLVGLA 158
Cdd:PRK05995  82 RADARRLADMLRAIYrcpKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIP----ATISPyviRAMGER 157
                        170       180
                 ....*....|....*....|....*....
gi 15235527  159 KATDMILLSKSISSEEGHKLGLIDALVPP 187
Cdd:PRK05995 158 AARRYFLTAERFDAAEALRLGLVHEVVPA 186
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
15-202 1.52e-13

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 71.54  E-value: 1.52e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   15 GVAVITISNPPV-NSLASP-IISGLKEKFRDANQRNDVKAIVLIGNNGRFS-GGfdiNVFQQVHKTGDLSLMPEvsvelv 91
Cdd:PRK09245  12 HIVTLTMNRPETrNALSDNdAVDALVAACAAINADRSVRAVILTGAGTAFSsGG---NVKDMRARVGAFGGSPA------ 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   92 cNLMEDSRK--------------PVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGL 157
Cdd:PRK09245  83 -DIRQGYRHgiqriplalynlevPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPGDGGAWLLPRIIGM 161
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 15235527  158 AKATDMILLSKSISSEEGHKLGLIDALVPPGDVLSTSRKWALDIA 202
Cdd:PRK09245 162 ARAAEMAFTGDAIDAATALEWGLVSRVVPADQLLPAARALAERIA 206
PRK06213 PRK06213
crotonase/enoyl-CoA hydratase family protein;
13-198 9.77e-13

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235744  Cd Length: 229  Bit Score: 68.08  E-value: 9.77e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   13 NDGVAVITISNPPVNSLASPIISGLKEKFRDANQrnDVKAIVLIGNNGRFSGGFDINVFQQvhktgdlslMPEVSVELVC 92
Cdd:PRK06213  10 EDGVATITLDDGKVNALSPAMIDALNAALDQAED--DRAVVVITGQPGIFSGGFDLKVMTS---------GAQAAIALLT 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   93 NLMEDSR------KPVVAAVEGLALGGGLELAMACHARVAAPKA-QLGLPELTLG-VIPGFG---GTQRLPRlVGLAKAt 161
Cdd:PRK06213  79 AGSTLARrllshpKPVIVACTGHAIAKGAFLLLSADYRIGVHGPfKIGLNEVAIGmTMPHAAielARDRLTP-SAFQRA- 156
                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 15235527  162 dmILLSKSISSEEGHKLGLIDALVPPGDVLSTSRKWA 198
Cdd:PRK06213 157 --VINAEMFDPEEAVAAGFLDEVVPPEQLLARAQAAA 191
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
15-233 2.02e-11

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 64.81  E-value: 2.02e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   15 GVAVITISNP-PVNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINVFQqVHKTGDLSLMPEVsVELVCN 93
Cdd:PRK06023  15 GVQVIRFNRPeKKNAITRAMYATMAKALKAADADDAIRAHVFLGTEGCFSAGNDMQDFL-AAAMGGTSFGSEI-LDFLIA 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   94 LMEdSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMILLSKSISSE 173
Cdd:PRK06023  93 LAE-AEKPIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSSLLAPRLMGHQRAFALLALGEGFSAE 171
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  174 EGHKLGLIDALVPPGDVLSTSRKWALDIAegRKPfLQSLhrtdKIgslseARAILKNSRQ 233
Cdd:PRK06023 172 AAQEAGLIWKIVDEEAVEAETLKAAEELA--AKP-PQAL----QI-----ARDLMRGPRE 219
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
3-181 2.25e-11

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 64.92  E-value: 2.25e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527    3 KKIGVTMEVGNDGVAVITISNPPV-NSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINVFQQVHK---TG 78
Cdd:PLN02664   5 KTLEIIQKSPNSSVFHLNLNRPSQrNALSLDFFTEFPKALSSLDQNPNVSVIILSGAGDHFCSGIDLKTLNSISEqssSG 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   79 DLSLMPE------VSVELVCNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLP 152
Cdd:PLN02664  85 DRGRSGErlrrkiKFLQDAITAIEQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGTLQRLP 164
                        170       180
                 ....*....|....*....|....*....
gi 15235527  153 RLVGLAKATDMILLSKSISSEEGHKLGLI 181
Cdd:PLN02664 165 SIVGYGNAMELALTGRRFSGSEAKELGLV 193
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
14-209 2.74e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 64.41  E-value: 2.74e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   14 DGVAVITISNP-PVNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINVFqqvhkTGDLSLMPEVSVELVC 92
Cdd:PRK06072   8 EGYAIVTMSRPdKLNALNLEMRNEFISKLKQINADPKIRVVIVTGEGRAFCVGADLSEF-----APDFAIDLRETFYPII 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   93 NLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGlAKATDMILLSKSISS 172
Cdd:PRK06072  83 REIRFSDKIYISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLKLTG-QRFYEILVLGGEFTA 161
                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 15235527  173 EEGHKLGLIDALVPPgdvLSTSRKWALDIAEGrkPFL 209
Cdd:PRK06072 162 EEAERWGLLKISEDP---LSDAEEMANRISNG--PFQ 193
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
3-194 4.89e-11

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 64.13  E-value: 4.89e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527    3 KKIGVTMEVGNDGVAVITISNPPVNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGR--FSGGFDINvfqQVHKtgdl 80
Cdd:PLN03214   9 ATPGVRVDRRPGGIAVVWLAKEPVNSMTLAMWRSLDDALTALENDPTVRGVVFASGLRRdvFTAGNDIA---ELYA---- 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   81 slmPEVSVE-----------LVCNLMEdSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGV-IPGFGGT 148
Cdd:PLN03214  82 ---PKTSAAryaefwltqttFLVRLLR-SRLATVCAIRGACPAGGCAVSLCCDYRLQTTEGTMGLNEVALGIpVPKFWAR 157
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 15235527  149 QRLPRLVGLAKATDMILLSKSISSEEGHKLGLIDALVPPGDVLSTS 194
Cdd:PLN03214 158 LFMGRVIDRKVAESLLLRGRLVRPAEAKQLGLIDEVVPAAALMEAA 203
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
14-203 8.34e-11

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 63.12  E-value: 8.34e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   14 DGVAVITISNPPV-NSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINVFQQVHK--TGDLSLMPEVSvEL 90
Cdd:PRK07327  20 PGVLEIVLNGPGAlNAADARMHRELADIWRDVDRDPDVRVVLIRGEGKAFSAGGDLALVEEMADdfEVRARVWREAR-DL 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   91 VCNLMeDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMILLSKSI 170
Cdd:PRK07327  99 VYNVI-NCDKPIVSAIHGPAVGAGLVAALLADISIAAKDARIIDGHTRLGVAAGDHAAIVWPLLCGMAKAKYYLLLCEPV 177
                        170       180       190
                 ....*....|....*....|....*....|...
gi 15235527  171 SSEEGHKLGLIDALVPPGDVLSTsrkwALDIAE 203
Cdd:PRK07327 178 SGEEAERIGLVSLAVDDDELLPK----ALEVAE 206
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
13-252 9.92e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 62.74  E-value: 9.92e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   13 NDGVAVITISNPPV-NSLASPIISGLKEKFRDAnQRNDVKaIVLIGNNGR-FSGGFDINVFQQVHKTGDL-SLMPEVSvE 89
Cdd:PRK07659  13 EGRVATIMLNRPEAlNALDEPMLKELLQALKEV-AESSAH-IVVLRGNGRgFSAGGDIKMMLSSNDESKFdGVMNTIS-E 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   90 LVCNLMeDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMILLSKS 169
Cdd:PRK07659  90 IVVTLY-TMPKLTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQKRVGENKAKQIIWEGKK 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  170 ISSEEGHKLGLIDALVpPGDVLSTSRKWaldIAEGRKPFLQSLHRTDKI-GSLSEARaiLKNSRQLAKKIAPNMPQHHAC 248
Cdd:PRK07659 169 LSATEALDLGLIDEVI-GGDFQTAAKQK---ISEWLQKPLKAMIETKQIyCELNRSQ--LEQVLQLEKRAQYAMRQTADH 242

                 ....
gi 15235527  249 IEVI 252
Cdd:PRK07659 243 KEGI 246
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
99-203 5.24e-10

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 60.74  E-value: 5.24e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   99 RKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPgFGG-TQRLPRLVGLAKATDMILLSKSISSEEGHK 177
Cdd:PRK06563  92 SKPLVVAVQGYCLTLGIELMLAADIVVAADNTRFAQLEVQRGILP-FGGaTLRFPQAAGWGNAMRYLLTGDEFDAQEALR 170
                         90       100
                 ....*....|....*....|....*.
gi 15235527  178 LGLIDALVPPGDVLSTsrkwALDIAE 203
Cdd:PRK06563 171 LGLVQEVVPPGEQLER----AIELAE 192
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
14-204 1.07e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 59.93  E-value: 1.07e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   14 DGVAVITISNPP-VNSLASPIISGLKEKFRDAnQRNDVKAIVLIGNnGR-FSGGFDIN--VFQQVHKTGDLSlmpeVSVE 89
Cdd:PRK08140  12 AGVATLTLNRPDkLNSFTREMHRELREALDQV-EDDGARALLLTGA-GRgFCAGQDLAdrDVTPGGAMPDLG----ESIE 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   90 -----LVcNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMI 164
Cdd:PRK08140  86 tfynpLV-RRLRALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPRLVGMARALGLA 164
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 15235527  165 LLSKSISSEEGHKLGLIDALVPPGDVLSTSRKWALDIAEG 204
Cdd:PRK08140 165 LLGEKLSAEQAEQWGLIWRVVDDAALADEAQQLAAHLATQ 204
PRK08788 PRK08788
enoyl-CoA hydratase; Validated
60-189 1.60e-09

enoyl-CoA hydratase; Validated


Pssm-ID: 236338  Cd Length: 287  Bit Score: 59.54  E-value: 1.60e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   60 GRFSGGFDINVFQQVHKTGDL-SLM--PEVSVELVCNLMEDSRKPVV--AAVEGLALGGGLELAMACHARVAAPKAQLGL 134
Cdd:PRK08788  77 GVFNLGGDLALFAELIRAGDRdALLayARACVDGVHAFHRGFGAGAIsiALVQGDALGGGFEAALSHHTIIAERGAKMGF 156
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 15235527  135 PELTLGVIPGFGGTQRLPRLVGLAKATDMILLSKSISSEEGHKLGLIDALVPPGD 189
Cdd:PRK08788 157 PEILFNLFPGMGAYSFLARRVGPKLAEELILSGKLYTAEELHDMGLVDVLVEDGQ 211
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
14-198 1.71e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 58.97  E-value: 1.71e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   14 DGVAVITISNPP-VNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINvfqqvhktgDLSLMPEVSVELVC 92
Cdd:PRK05870  11 DGVALITVNDPDrRNAVTAEMSAQLRAAVAAAEADPDVHALVVTGAGKAFCAGADLT---------ALGAAPGRPAEDGL 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   93 NLMEDS-------RKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMIL 165
Cdd:PRK05870  82 RRIYDGflavascPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAVGPQVARAALL 161
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 15235527  166 LSKSISSEEGHKLGLIDALV--PPGDVLSTSRKWA 198
Cdd:PRK05870 162 FGMRFDAEAAVRHGLALMVAddPVAAALELAAGPA 196
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
14-207 2.95e-09

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 58.44  E-value: 2.95e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   14 DGVAVITIsNPPV--NSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINVFQQVhKTGDLslmpEVSVELV 91
Cdd:PRK07110  13 EGIAQVTM-QDRVnkNAFSDELCDQLHEAFDTIAQDPRYKVVILTGYPNYFATGGTQEGLLSL-QTGKG----TFTEANL 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   92 CNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMILLSKSIS 171
Cdd:PRK07110  87 YSLALNCPIPVIAAMQGHAIGGGLVLGLYADIVVLSRESVYTANFMKYGFTPGMGATAILPEKLGLALGQEMLLTARYYR 166
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 15235527  172 SEEGHKLGLIDALVPPGDVLSTSRKWALDIAEgrKP 207
Cdd:PRK07110 167 GAELKKRGVPFPVLPRAEVLEKALELARSLAE--KP 200
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
7-203 3.26e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 58.82  E-value: 3.26e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527    7 VTMEVgNDGVAVITISNPPV-NSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDI---------NVFQQVHK 76
Cdd:PRK08290   6 VRYEV-AGRIARITLNRPEArNAQNRQMLYELDAAFRRAEADDAVRVIVLAGAGKHFSAGHDLgsgtpgrdrDPGPDQHP 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   77 TGDLSLMPEVSVEL-----------VCNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGvIPG- 144
Cdd:PRK08290  85 TLWWDGATKPGVEQryarewevylgMCRRWRDLPKPTIAQVQGACIAGGLMLAWVCDLIVASDDAFFSDPVVRMG-IPGv 163
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15235527  145 --FGGTQRL-PRlvglaKATDMILLSKSISSEEGHKLGLIDALVPPGDVLSTSRKWALDIAE 203
Cdd:PRK08290 164 eyFAHPWELgPR-----KAKELLFTGDRLTADEAHRLGMVNRVVPRDELEAETLELARRIAA 220
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
8-189 3.35e-09

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 58.15  E-value: 3.35e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527    8 TMEVGND--GVAVITISNPPV-NSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINVFQ-QVHKTGDLSLM 83
Cdd:PRK07468   5 TIRIAVDarGVATLTLNRPEKhNALSARMIAELTTAARRLAADAAVRVVVLTGAGKSFCAGGDLGWMRaQMTADRATRIE 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   84 PEVSVELVCNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRlVGLAKATDM 163
Cdd:PRK07468  85 EARRLAMMLKALNDLPKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVAR-MGEANARRV 163
                        170       180
                 ....*....|....*....|....*.
gi 15235527  164 ILLSKSISSEEGHKLGLIDALVPPGD 189
Cdd:PRK07468 164 FMSARLFDAEEAVRLGLLSRVVPAER 189
PRK07066 PRK07066
L-carnitine dehydrogenase;
309-545 6.07e-09

L-carnitine dehydrogenase;


Pssm-ID: 168796 [Multi-domain]  Cd Length: 321  Bit Score: 58.31  E-value: 6.07e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  309 IKKVAVIGGGLMGSGIATALLLSNIRVVLKEiNSEFLMKGIKSVEANMKSLVSRGKLTQDKAGKALSLFKGVLDYTEfnD 388
Cdd:PRK07066   7 IKTFAAIGSGVIGSGWVARALAHGLDVVAWD-PAPGAEAALRANVANAWPALERQGLAPGASPARLRFVATIEACVA--D 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  389 VDMVIEAVIENIQLKQNIFKEIEKVCSPHCILASNTSTIDLDVIGEKTNSKDRIVGAHFFSPAHLMPLLEIVRSKNTSAQ 468
Cdd:PRK07066  84 ADFIQESAPEREALKLELHERISRAAKPDAIIASSTSGLLPTDFYARATHPERCVVGHPFNPVYLLPLVEVLGGERTAPE 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527  469 VILDLMAVGKAIKKVPVVVGNCI-GFAVNRTFFPYSQAAHMLANLGVDLF-RIDSVItSFGLPL-----GPFQLGDLAGH 541
Cdd:PRK07066 164 AVDAAMGIYRALGMRPLHVRKEVpGFIADRLLEALWREALHLVNEGVATTgEIDDAI-RFGAGIrwsfmGTFLTYTLAGG 242

                 ....
gi 15235527  542 GIGL 545
Cdd:PRK07066 243 DAGM 246
PLN02921 PLN02921
naphthoate synthase
14-197 6.57e-09

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 58.26  E-value: 6.57e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   14 DGVAVITISNPPV-NSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGR-FSGGFDinvfQQVHKTG---DLSLMPEVSV 88
Cdd:PLN02921  75 EGIAKITINRPERrNAFRPRTVKELQRAFNDARDDSSVGVIILTGKGTKaFCSGGD----QAVRGKDgyvGPDDAGRLNV 150
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   89 ELVCNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMILLSK 168
Cdd:PLN02921 151 LDLQIQIRRLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSFDAGYGSSIMARLVGQKKAREMWFLAR 230
                        170       180
                 ....*....|....*....|....*....
gi 15235527  169 SISSEEGHKLGLIDALVPPGDVLSTSRKW 197
Cdd:PLN02921 231 FYTASEALKMGLVNTVVPLDELEGETVKW 259
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
8-191 3.06e-08

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 55.46  E-value: 3.06e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527    8 TMEVGNDG-VAVITISNPPVNSlasPIISGLKEKFRDANQR--NDVKAIVLIGNNGRFSGGFDinvFQQVHKTGDLSLMP 84
Cdd:PRK07112   5 TIRVRQQGdVCFLQLHRPEAQN---TINDRLIAECMDVLDRceHAATIVVLEGLPEVFCFGAD---FSAIAEKPDAGRAD 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   85 EVSVELVCNL---MEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPG----FggtqrLPRLVGL 157
Cdd:PRK07112  79 LIDAEPLYDLwhrLATGPYVTIAHVRGKVNAGGIGFVAASDIVIADETAPFSLSELLFGLIPAcvlpF-----LIRRIGT 153
                        170       180       190
                 ....*....|....*....|....*....|....
gi 15235527  158 AKATDMILLSKSISSEEGHKLGLIDALVPPGDVL 191
Cdd:PRK07112 154 QKAHYMTLMTQPVTAQQAFSWGLVDAYGANSDTL 187
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
5-203 3.46e-08

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 55.03  E-value: 3.46e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527    5 IGVTmevgNDG-VAVITISNPPV-NSLASPIISGLKEKFRDANQrNDVKAIVLIGNNGRFSGGFDI--NVFQqvhktgdl 80
Cdd:PRK07854   2 IGVT----RDGqVLTIELQRPERrNALNAELCEELREAVRKAVD-ESARAIVLTGQGTVFCAGADLsgDVYA-------- 68
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   81 SLMPEVSVELVcNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKA 160
Cdd:PRK07854  69 DDFPDALIEML-HAIDAAPVPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGIALDNWTIRRLSSLVGGGRA 147
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 15235527  161 TDMILLSKSISSEEGHKLGLIDALvppgDVLSTSRKWALDIAE 203
Cdd:PRK07854 148 RAMLLGAEKLTAEQALATGMANRI----GTLADAQAWAAEIAG 186
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
13-183 3.72e-07

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 51.99  E-value: 3.72e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   13 NDGVAVITISNPP-VNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINvfqqvhKTGDLSLMPEVS---- 87
Cdd:PRK07827  13 DGGVATLTLDSPHnRNALSARLVAQLHDGLRAAAADPAVRAVVLTHTGGTFCAGADLS------EAGGGGGDPYDAavar 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   88 ----VELVCNLMEdSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAkATDM 163
Cdd:PRK07827  87 aremTALLRAIVE-LPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAIISLTLLPRLSPRA-AARY 164
                        170       180
                 ....*....|....*....|
gi 15235527  164 ILLSKSISSEEGHKLGLIDA 183
Cdd:PRK07827 165 YLTGEKFGAAEAARIGLVTA 184
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
1-181 4.77e-07

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 51.80  E-value: 4.77e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527    1 MAKKIGVTMEvgnDGVAVITISNP-PVNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDInvfqqvhktGD 79
Cdd:PRK07509   1 MMDRVSVTIE---DGIADVRLNRPdKMNALDFAMFEELIATIKRLKKDRGIRAVILSGEGGAFCAGLDV---------KS 68
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   80 LSLMPEVSVELvcnLMEDS--------------RK---PVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVI 142
Cdd:PRK07509  69 VASSPGNAVKL---LFKRLpgnanlaqrvslgwRRlpvPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLV 145
                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 15235527  143 PGFGGTQRLPRLVGLAKATDMILLSKSISSEEGHKLGLI 181
Cdd:PRK07509 146 PDMAGTVSLRGLVRKDVARELTYTARVFSAEEALELGLV 184
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
7-203 1.83e-06

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 50.01  E-value: 1.83e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527    7 VTMEVgNDGVAVITISNPPVNSLASPIISG-LKEKFRDANQRNDVKAIVLIGNNGRFSGGFDIN-VFQQVHKTGDLslmp 84
Cdd:PRK09120  10 VKVEV-EDGIAWVTLNRPEKRNAMSPTLNReMIDVLDALEFDDDAGVLVLTGAGDAWSAGMDLKeYFRETDAQPEI---- 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   85 evsvelvcnLMEDSR--------------KPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQR 150
Cdd:PRK09120  85 ---------LQERIRreaygwwrrlrwyqKPTIAMVNGWCFGGGFSPLVACDLAIAADEAQFGLSEINWGIPPGGGVSKA 155
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 15235527  151 LPRLVGLAKATDMILLSKSISSEEGHKLGLIDALVPPGDVLSTSRKWALDIAE 203
Cdd:PRK09120 156 MADTVGHRDALYYIMTGETFTGRKAAEMGLVNESVPLAQLRARTRELAAKLLE 208
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
14-203 2.08e-06

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 49.64  E-value: 2.08e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   14 DGVAVITISNPP-VNSLASPIISGLKEKFRDANQRnDVKAIVLIGNNGR--FSGGFDINVFQQVHKT----GDlslmpev 86
Cdd:PRK11423  12 NKIATITFNNPAkRNALSKVLIDDLMQALSDLNRP-EIRVVILRAPSGSkvWSAGHDIHELPSGGRDplsyDD------- 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   87 SVELVCNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMILL 166
Cdd:PRK11423  84 PLRQILRMIQKFPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGVPYNLSGILNFTNDAGFHIVKEMFFT 163
                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 15235527  167 SKSISSEEGHKLGLIDALVPPGDVLSTSRKWALDIAE 203
Cdd:PRK11423 164 ASPITAQRALAVGILNHVVEVEELEDFTLQMAHHISE 200
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
13-202 3.63e-05

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 46.09  E-value: 3.63e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   13 NDGVAVITISNPP-VNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINVFQqVHKTGDL--SLMPEVSVe 89
Cdd:PRK08139  18 RDGVATLTLNRPQaFNALSEAMLAALQAALDAIAADPSVRVVVLAAAGKAFCAGHDLKEMR-AARGLAYfrALFARCSR- 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   90 lvcnLME---DSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVI---PGFGgtqrLPRLVGLAKATDM 163
Cdd:PRK08139  96 ----VMQaivALPQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIGLFcstPMVA----LSRNVPRKQAMEM 167
                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 15235527  164 ILLSKSISSEEGHKLGLIDALVPPGDVLSTSRKWALDIA 202
Cdd:PRK08139 168 LLTGEFIDAATAREWGLVNRVVPADALDAAVARLAAVIA 206
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
14-203 5.51e-05

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 45.65  E-value: 5.51e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   14 DGVAVITISNPPV-NSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGR-FSGGFDinvfQQVHKTG---DLSLMPEVSV 88
Cdd:PRK07396  21 DGIAKITINRPEVrNAFRPKTVKEMIDAFADARDDDNIGVIILTGAGDKaFCSGGD----QKVRGYGgyvDDDGVPRLNV 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   89 ELVCNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMILLSK 168
Cdd:PRK07396  97 LDLQRLIRTCPKPVIAMVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGYGASYLARIVGQKKAREIWFLCR 176
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 15235527  169 SISSEEGHKLGLIDALVPPGDVLSTSRKWALDIAE 203
Cdd:PRK07396 177 QYDAQEALDMGLVNTVVPLADLEKETVRWCREMLQ 211
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
16-186 6.34e-05

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 45.54  E-value: 6.34e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527    16 VAVITISNPPV-NSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGR-FSGGFDINVFQQVHKTGDLSLMPEVSVEL--V 91
Cdd:pfam16113   1 VGVITLNRPKAlNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERaFCAGGDVRALYEAAKAGGGEAGRDFFREEyrL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527    92 CNLMEDSRKPVVAaveglalggglelAM-----------ACHA--RVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVG-- 156
Cdd:pfam16113  81 NYLIATYPKPYVA-------------LMdgivmgggvglSVHGsfRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGel 147
                         170       180       190
                  ....*....|....*....|....*....|...
gi 15235527   157 ---LAkatdmiLLSKSISSEEGHKLGLIDALVP 186
Cdd:pfam16113 148 glyLA------LTGARLNGADALAAGLATHYVP 174
3HCDH pfam00725
3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; This family also includes lambda ...
624-700 5.46e-04

3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; This family also includes lambda crystallin. Some proteins include two copies of this domain.


Pssm-ID: 395588 [Multi-domain]  Cd Length: 97  Bit Score: 39.51  E-value: 5.46e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15235527   624 IVEMILFPVVNEACRVLDEGVViRASDLDIASVLGMSFPSyrgGIVFWADTVGPkyiyERLKKLSETYGSFFKPSRY 700
Cdd:pfam00725   3 VVNRLLAPYLNEAIRLVEEGVA-TPEDIDAAMRLGLGLPM---GPFELSDLVGL----DVGYHILEVLAEEFGDRAY 71
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
14-156 1.90e-03

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 41.32  E-value: 1.90e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   14 DGVAVITISNPPV-NSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINVFQQvHKTGDLSLMPEVSVEL-V 91
Cdd:PLN02874  19 GRVRVITLNRPRQlNVISLSVVSLLAEFLEQWEKDDSVELIIIKGAGRAFSAGGDLKMFYD-GRESDDSCLEVVYRMYwL 97
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15235527   92 CNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVG 156
Cdd:PLN02874  98 CYHIHTYKKTQVALVHGLVMGGGAGLMVPMKFRVVTEKTVFATPEASVGFHTDCGFSYILSRLPG 162
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
1-157 2.08e-03

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 41.24  E-value: 2.08e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527    1 MAKKIGVTMEvGNDGVAVITISNPP-VNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINVFQQVHKTGD 79
Cdd:PLN02988   5 MASQSQVLVE-EKSSVRILTLNRPKqLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDIEQGN 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235527   80 LSLMPEV-SVELVCN-LMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGL 157
Cdd:PLN02988  84 WRLGANFfSDEYMLNyVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGF 163
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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