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Conserved domains on  [gi|22329002|ref|NP_194589|]
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no pollen germination related 2 [Arabidopsis thaliana]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11459274)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 596-729 1.60e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 74.26  E-value: 1.60e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 596 HDLAHIYINLSQWRDAESCLSRSRLIAPYSSVRYHIEGVLYNRRGQLEEAMEAFTTALDIDPMHVPSLTSKAEILLEVGn 675
Cdd:COG3914  82 ELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLG- 160

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....
gi 22329002 676 RSGIAVvrSFLMEALRIDRLNHSAWYNLGKMFKAEGSVssmQEAVECFQAAVTL 729
Cdd:COG3914 161 RLEEAI--AALRRALELDPDNAEALNNLGNALQDLGRL---EEAIAAYRRALEL 209
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 455-693 6.76e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 57.43  E-value: 6.76e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 455 QALESADMTNPRVVHRLALENAEQRKLDSALAYAKEALKLgAESDLEVWLLLARVLSAQKRFSDAETIVDAALNETGKWE 534
Cdd:COG2956  66 QKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLEL-DPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENA 144

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 535 QgkLLRLKAKLRLAKGEVKDAIKTYTQLLALLqvqsksfnsakklpKGYVKELMSlelgtwhdLAHIYINLSQWRDAESC 614
Cdd:COG2956 145 H--AYCELAELYLEQGDYDEAIEALEKALKLD--------------PDCARALLL--------LAELYLEQGDYEEAIAA 200

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 615 LSRSRLIAP-YSSVRYHIeGVLYNRRGQLEEAMEAFTTALDIDPmHVPSLTSKAEILLEvgnRSGIAVVRSFLMEALRID 693
Cdd:COG2956 201 LERALEQDPdYLPALPRL-AELYEKLGDPEEALELLRKALELDP-SDDLLLALADLLER---KEGLEAALALLERQLRRH 275
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 596-729 1.60e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 74.26  E-value: 1.60e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 596 HDLAHIYINLSQWRDAESCLSRSRLIAPYSSVRYHIEGVLYNRRGQLEEAMEAFTTALDIDPMHVPSLTSKAEILLEVGn 675
Cdd:COG3914  82 ELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLG- 160

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....
gi 22329002 676 RSGIAVvrSFLMEALRIDRLNHSAWYNLGKMFKAEGSVssmQEAVECFQAAVTL 729
Cdd:COG3914 161 RLEEAI--AALRRALELDPDNAEALNNLGNALQDLGRL---EEAIAAYRRALEL 209
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 455-693 6.76e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 57.43  E-value: 6.76e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 455 QALESADMTNPRVVHRLALENAEQRKLDSALAYAKEALKLgAESDLEVWLLLARVLSAQKRFSDAETIVDAALNETGKWE 534
Cdd:COG2956  66 QKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLEL-DPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENA 144

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 535 QgkLLRLKAKLRLAKGEVKDAIKTYTQLLALLqvqsksfnsakklpKGYVKELMSlelgtwhdLAHIYINLSQWRDAESC 614
Cdd:COG2956 145 H--AYCELAELYLEQGDYDEAIEALEKALKLD--------------PDCARALLL--------LAELYLEQGDYEEAIAA 200

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 615 LSRSRLIAP-YSSVRYHIeGVLYNRRGQLEEAMEAFTTALDIDPmHVPSLTSKAEILLEvgnRSGIAVVRSFLMEALRID 693
Cdd:COG2956 201 LERALEQDPdYLPALPRL-AELYEKLGDPEEALELLRKALELDP-SDDLLLALADLLER---KEGLEAALALLERQLRRH 275
TPR_19 pfam14559
Tetratricopeptide repeat;
478-530 1.21e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 37.95  E-value: 1.21e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 22329002   478 QRKLDSALAYAKEALKLgAESDLEVWLLLARVLSAQKRFSDAETIVDAALNET 530
Cdd:pfam14559   1 EGDYAEALELLEQALAE-DPDNAEARLGLAEALLALGRLDEAEALLAALPAAD 52
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 557-729 4.70e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.45  E-value: 4.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002   557 KTYTQLLALLQVQsKSFNSAKKLpkGYVKELMSLelgtwhDLAHIYINLSQWRDA-ESCLSRSRLIAPYSSVRYHIEGVL 635
Cdd:TIGR02917  64 KIYLALGDYAAAE-KELRKALSL--GYPKNQVLP------LLARAYLLQGKFQQVlDELPGKTLLDDEGAAELLALRGLA 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002   636 YNRRGQLEEAMEAFTTALDIDPMHVPSLTSKAEILLEVGNRSGiavVRSFLMEALRIDRLNHSAWYNLGKMfkaEGSVSS 715
Cdd:TIGR02917 135 YLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDE---ARALIDEVLTADPGNVDALLLKGDL---LLSLGN 208

                         170
                  ....*....|....
gi 22329002   716 MQEAVECFQAAVTL 729
Cdd:TIGR02917 209 IELALAAYRKAIAL 222
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 478-663 5.38e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.07  E-value: 5.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002   478 QRKLDSALAYAKEALKLgAESDLEVWLLLARVLSAQKRFSDAETIVDAALNETGKweQGKLLRLKAKLRLAKGEVKDAIK 557
Cdd:TIGR02917 138 LGQLELAQKSYEQALAI-DPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPG--NVDALLLKGDLLLSLGNIELALA 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002   558 TYTQLLALlqvqsksfnsAKKLPKGYVKelmslelgtwhdLAHIYINLSQWRDAESCLSRSRLIAPYSSVRYHIEGVLYN 637
Cdd:TIGR02917 215 AYRKAIAL----------RPNNIAVLLA------------LATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVDF 272

                         170       180
                  ....*....|....*....|....*.
gi 22329002   638 RRGQLEEAMEAFTTALDIDPMHVPSL 663
Cdd:TIGR02917 273 QKKNYEDARETLQDALKSAPEYLPAL 298
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 596-729 1.60e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 74.26  E-value: 1.60e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 596 HDLAHIYINLSQWRDAESCLSRSRLIAPYSSVRYHIEGVLYNRRGQLEEAMEAFTTALDIDPMHVPSLTSKAEILLEVGn 675
Cdd:COG3914  82 ELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLG- 160

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....
gi 22329002 676 RSGIAVvrSFLMEALRIDRLNHSAWYNLGKMFKAEGSVssmQEAVECFQAAVTL 729
Cdd:COG3914 161 RLEEAI--AALRRALELDPDNAEALNNLGNALQDLGRL---EEAIAAYRRALEL 209
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 471-735 2.35e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 70.91  E-value: 2.35e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 471 LALENAEQRKLDSALAYAKEALKLGAEsDLEVWLLLARVLSAQKRFSDAETIVDAALNETGKWEQgkllrlkaklrlakg 550
Cdd:COG2956  14 KGLNYLLNGQPDKAIDLLEEALELDPE-TVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAE--------------- 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 551 evkdaiktYTQLLALLQVQSKSFNSAKKLpkgyVKELMSLE---LGTWHDLAHIYINLSQWRDAESCLSRSRLIAPYSSV 627
Cdd:COG2956  78 --------ALLELAQDYLKAGLLDRAEEL----LEKLLELDpddAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAH 145

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 628 RYHIEGVLYNRRGQLEEAMEAFTTALDIDPMHVPSLTSKAEILLEVGNrsgIAVVRSFLMEALRIDRLNHSAWYNLGKMF 707
Cdd:COG2956 146 AYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGD---YEEAIAALERALEQDPDYLPALPRLAELY 222

                       250       260
                ....*....|....*....|....*...
gi 22329002 708 KAEGSVssmQEAVECFQAAVTLEETMPV 735
Cdd:COG2956 223 EKLGDP---EEALELLRKALELDPSDDL 247
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
594-730 1.20e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 68.49  E-value: 1.20e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 594 TWHDLAHIYINLSQWRDAESCLSRSRLIAPYSSVRYHIEGVLYNRRGQLEEAMEAFTTALDIDPMHVPSLTSKAEILLEV 673
Cdd:COG0457  10 AYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQAL 89

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 22329002 674 GNRSGiAVvrSFLMEALRIDRLNHSAWYNLGKMFKAEGSVssmQEAVECFQAAVTLE 730
Cdd:COG0457  90 GRYEE-AL--EDYDKALELDPDDAEALYNLGLALLELGRY---DEAIEAYERALELD 140
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
594-726 1.56e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 61.95  E-value: 1.56e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 594 TWHDLAHIYINLSQWRDAESCLSRSRLIAPYSSVRYHIEGVLYNRRGQLEEAMEAFTTALDIDPMHVPSLTSKAEILLEV 673
Cdd:COG0457  44 ALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLEL 123

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|...
gi 22329002 674 GNRSGiavVRSFLMEALRIDRLNHSAWYNLGKMFKAEGsvsSMQEAVECFQAA 726
Cdd:COG0457 124 GRYDE---AIEAYERALELDPDDADALYNLGIALEKLG---RYEEALELLEKL 170
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 455-693 6.76e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 57.43  E-value: 6.76e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 455 QALESADMTNPRVVHRLALENAEQRKLDSALAYAKEALKLgAESDLEVWLLLARVLSAQKRFSDAETIVDAALNETGKWE 534
Cdd:COG2956  66 QKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLEL-DPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENA 144

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 535 QgkLLRLKAKLRLAKGEVKDAIKTYTQLLALLqvqsksfnsakklpKGYVKELMSlelgtwhdLAHIYINLSQWRDAESC 614
Cdd:COG2956 145 H--AYCELAELYLEQGDYDEAIEALEKALKLD--------------PDCARALLL--------LAELYLEQGDYEEAIAA 200

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 615 LSRSRLIAP-YSSVRYHIeGVLYNRRGQLEEAMEAFTTALDIDPmHVPSLTSKAEILLEvgnRSGIAVVRSFLMEALRID 693
Cdd:COG2956 201 LERALEQDPdYLPALPRL-AELYEKLGDPEEALELLRKALELDP-SDDLLLALADLLER---KEGLEAALALLERQLRRH 275
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 469-703 5.61e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 56.15  E-value: 5.61e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 469 HRLALENAEQRKLDSALAYAKEALKLGAESDLEVW------LLLARVLSAQKRFSDAETIVDAALNETGKWEQGKLLRLK 542
Cdd:COG3914   5 ALLALAALAAAALLAAAAAAELALAAELEAAALAAalglalLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELA 84

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 543 AKLRLAKGEVKDAIKTYTQLLALlqvqsksfnsakklpkgyvkelMSLELGTWHDLAHIYINLSQWRDAESCLSRSRLIA 622
Cdd:COG3914  85 ALLLQALGRYEEALALYRRALAL----------------------NPDNAEALFNLGNLLLALGRLEEALAALRRALALN 142

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 623 PYSSVRYHIEGVLYNRRGQLEEAMEAFTTALDIDPMHVPSLTSKAEILLEVGNRS-GIAVVRsflmEALRIDRLNHSAWY 701
Cdd:COG3914 143 PDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEeAIAAYR----RALELDPDNADAHS 218


                ..
gi 22329002 702 NL 703
Cdd:COG3914 219 NL 220
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
621-730 9.10e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 53.86  E-value: 9.10e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 621 IAPYSSVRYHIEGVLYNRRGQLEEAMEAFTTALDIDPMHVPSLTSKAEILLEVGNRSGiavVRSFLMEALRIDRLNHSAW 700
Cdd:COG0457   3 LDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEE---ALADYEQALELDPDDAEAL 79

                        90       100       110
                ....*....|....*....|....*....|
gi 22329002 701 YNLGKMFKAEGSVssmQEAVECFQAAVTLE 730
Cdd:COG0457  80 NNLGLALQALGRY---EEALEDYDKALELD 106
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 563-675 2.76e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 50.19  E-value: 2.76e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 563 LALLQVQSKSFNSAKKLpkgyVKELMSLE---LGTWHDLAHIYINLSQWRDAESCLSRSRLIAPYSSVRYHIEGVLYNRR 639
Cdd:COG4783  10 LAQALLLAGDYDEAEAL----LEKALELDpdnPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKA 85

                        90       100       110
                ....*....|....*....|....*....|....*.
gi 22329002 640 GQLEEAMEAFTTALDIDPMHVPSLTSKAEILLEVGN 675
Cdd:COG4783  86 GDYDEALALLEKALKLDPEHPEAYLRLARAYRALGR 121
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 633-729 3.01e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 50.00  E-value: 3.01e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 633 GVLYNRRGQLEEAMEAFTTALDIDPMHVPSLTSKAEILLEVGNrsgIAVVRSFLMEALRIDRLNHSAWYNLGKMFKAEGs 712
Cdd:COG4235  24 GRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGD---TEEAEELLERALALDPDNPEALYLLGLAAFQQG- 99

                        90
                ....*....|....*..
gi 22329002 713 vsSMQEAVECFQAAVTL 729
Cdd:COG4235 100 --DYAEAIAAWQKLLAL 114
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
499-676 6.61e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 51.16  E-value: 6.61e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 499 DLEVWLLLARVLSAQKRFSDAETIVDAALNETGKWEQgkLLRLKAKLRLAKGEVKDAIKTYTQLLALlqvqskSFNSAKk 578
Cdd:COG0457   7 DAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAE--ALYNLGLAYLRLGRYEEALADYEQALEL------DPDDAE- 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 579 lpkgyvkelmslelgTWHDLAHIYINLSQWRDAESCLSRSRLIAPYSSVRYHIEGVLYNRRGQLEEAMEAFTTALDIDPM 658
Cdd:COG0457  78 ---------------ALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPD 142

                       170
                ....*....|....*...
gi 22329002 659 HVPSLTSKAEILLEVGNR 676
Cdd:COG0457 143 DADALYNLGIALEKLGRY 160
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 595-730 7.22e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 49.03  E-value: 7.22e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 595 WHDLAHIYINLSQWRDAESCLSRSRLIAPYSSVRYHIEGVLYNRRGQLEEAMEAFTTALDIDPMHVPSLTSKAEILLEVG 674
Cdd:COG4783   7 LYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAG 86

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 22329002 675 NRSGiAVvrSFLMEALRIDRLNHSAWYNLGKMFKAEGsvsSMQEAVECFQAAVTLE 730
Cdd:COG4783  87 DYDE-AL--ALLEKALKLDPEHPEAYLRLARAYRALG---RPDEAIAALEKALELD 136
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
601-693 2.43e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 46.32  E-value: 2.43e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 601 IYINLSQWRDAESCLSRSRLIAPYSSVRYHIEGVLYNRRGQLEEAmEAFTTALDIDPMHVPSLTSKAEILLEVGNRSGia 680
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEA-IALEKALKLDPNNAEALLNLAELLLELGDYDE-- 77

                        90
                ....*....|...
gi 22329002 681 vVRSFLMEALRID 693
Cdd:COG3063  78 -ALAYLERALELD 89
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
635-730 7.39e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 45.16  E-value: 7.39e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 635 LYNRRGQLEEAMEAFTTALDIDPMHVPSLTSKAEILLEVGNRSGiAVVrsfLMEALRIDRLNHSAWYNLGKMFKAEGSVs 714
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDE-AIA---LEKALKLDPNNAEALLNLAELLLELGDY- 75

                        90
                ....*....|....*.
gi 22329002 715 smQEAVECFQAAVTLE 730
Cdd:COG3063  76 --DEALAYLERALELD 89
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 634-730 5.91e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 44.18  E-value: 5.91e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 634 VLYNRRGQLEEAMEAFTTALDIDPMHVPSLTSKAEILLEVGNRSGiavVRSFLMEALRIDRLNHSAWYNLGKMFKAEGsv 713
Cdd:COG5010  62 NLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDE---AKEYYEKALALSPDNPNAYSNLAALLLSLG-- 136

                        90
                ....*....|....*..
gi 22329002 714 sSMQEAVECFQAAVTLE 730
Cdd:COG5010 137 -QDDEAKAALQRALGTS 152
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
464-654 1.35e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 44.23  E-value: 1.35e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 464 NPRVVHRLALENAEQRKLDSALAYAKEALKLgAESDLEVWLLLARVLSAQKRFSDAETIVDAALNEtgKWEQGKLLRLKA 543
Cdd:COG0457   7 DAEAYNNLGLAYRRLGRYEEAIEDYEKALEL-DPDDAEALYNLGLAYLRLGRYEEALADYEQALEL--DPDDAEALNNLG 83

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 544 KLRLAKGEVKDAIKTYTQLLALlqvqskSFNSAKklpkgyvkelmslelgTWHDLAHIYINLSQWRDAESCLSRSRLIAP 623
Cdd:COG0457  84 LALQALGRYEEALEDYDKALEL------DPDDAE----------------ALYNLGLALLELGRYDEAIEAYERALELDP 141

                       170       180       190
                ....*....|....*....|....*....|.
gi 22329002 624 YSSVRYHIEGVLYNRRGQLEEAMEAFTTALD 654
Cdd:COG0457 142 DDADALYNLGIALEKLGRYEEALELLEKLEA 172
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 445-528 1.68e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 44.98  E-value: 1.68e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 445 ERIARQSEGIQALESA---DMTNPRVVHRLALENAEQRKLDSALAYAKEALKLGAEsDLEVWLLLARVLSAQKRFSDAET 521
Cdd:COG3914  89 QALGRYEEALALYRRAlalNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPD-FAEAYLNLGEALRRLGRLEEAIA 167


                ....*..
gi 22329002 522 IVDAALN 528
Cdd:COG3914 168 ALRRALE 174
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 601-695 4.05e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 41.48  E-value: 4.05e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 601 IYINLSQWRDAESCLSRSRLIAPYSSVRYHIEGVLYNRRGQLEEAMEAFTTALDIDPMHVPSLTSKAEILLEVGNRsgiA 680
Cdd:COG5010  63 LYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQD---D 139

                        90
                ....*....|....*
gi 22329002 681 VVRSFLMEALRIDRL 695
Cdd:COG5010 140 EAKAALQRALGTSPL 154
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 497-657 8.72e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.18  E-value: 8.72e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 497 ESDLEVWLLLARVLSAQKRFSDAETIVDAALNETGKWEQgkllrlkaklrlakgevkdaiktYTQLLALLQVQSKSFNSA 576
Cdd:COG4783   1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPE-----------------------AFALLGEILLQLGDLDEA 57

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 577 KKlpkgYVKELMSL---ELGTWHDLAHIYINLSQWRDAESCLSRSRLIAPYSSVRYHIEGVLYNRRGQLEEAMEAFTTAL 653
Cdd:COG4783  58 IV----LLHEALELdpdEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKAL 133


                ....
gi 22329002 654 DIDP 657
Cdd:COG4783 134 ELDP 137
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
594-675 9.10e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 41.44  E-value: 9.10e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 594 TWHDLAHIYINLSQWRDAESCLSRSRLIAPYSSVRYHIEGVLYNRRGQLEEAMEAFTTALDIDPMHVPSLTSKAEILLEV 673
Cdd:COG4785  75 LYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYL 154


                ..
gi 22329002 674 GN 675
Cdd:COG4785 155 GR 156
TPR_19 pfam14559
Tetratricopeptide repeat;
478-530 1.21e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 37.95  E-value: 1.21e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 22329002   478 QRKLDSALAYAKEALKLgAESDLEVWLLLARVLSAQKRFSDAETIVDAALNET 530
Cdd:pfam14559   1 EGDYAEALELLEQALAE-DPDNAEARLGLAEALLALGRLDEAEALLAALPAAD 52
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 454-565 4.21e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 38.25  E-value: 4.21e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002 454 IQALESADMTNPRVVHRLALENAEQRKLDSALAYAKEALKLGAEsDLEVWLLLARVLSAQKRFSDAETIVDAALNETGkw 533
Cdd:COG4783  27 LEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPD-EPEARLNLGLALLKAGDYDEALALLEKALKLDP-- 103

                        90       100       110
                ....*....|....*....|....*....|..
gi 22329002 534 EQGKLLRLKAKLRLAKGEVKDAIKTYTQLLAL 565
Cdd:COG4783 104 EHPEAYLRLARAYRALGRPDEAIAALEKALEL 135
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 557-729 4.70e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.45  E-value: 4.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002   557 KTYTQLLALLQVQsKSFNSAKKLpkGYVKELMSLelgtwhDLAHIYINLSQWRDA-ESCLSRSRLIAPYSSVRYHIEGVL 635
Cdd:TIGR02917  64 KIYLALGDYAAAE-KELRKALSL--GYPKNQVLP------LLARAYLLQGKFQQVlDELPGKTLLDDEGAAELLALRGLA 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002   636 YNRRGQLEEAMEAFTTALDIDPMHVPSLTSKAEILLEVGNRSGiavVRSFLMEALRIDRLNHSAWYNLGKMfkaEGSVSS 715
Cdd:TIGR02917 135 YLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDE---ARALIDEVLTADPGNVDALLLKGDL---LLSLGN 208

                         170
                  ....*....|....
gi 22329002   716 MQEAVECFQAAVTL 729
Cdd:TIGR02917 209 IELALAAYRKAIAL 222
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 478-663 5.38e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.07  E-value: 5.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002   478 QRKLDSALAYAKEALKLgAESDLEVWLLLARVLSAQKRFSDAETIVDAALNETGKweQGKLLRLKAKLRLAKGEVKDAIK 557
Cdd:TIGR02917 138 LGQLELAQKSYEQALAI-DPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPG--NVDALLLKGDLLLSLGNIELALA 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22329002   558 TYTQLLALlqvqsksfnsAKKLPKGYVKelmslelgtwhdLAHIYINLSQWRDAESCLSRSRLIAPYSSVRYHIEGVLYN 637
Cdd:TIGR02917 215 AYRKAIAL----------RPNNIAVLLA------------LATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVDF 272

                         170       180
                  ....*....|....*....|....*.
gi 22329002   638 RRGQLEEAMEAFTTALDIDPMHVPSL 663
Cdd:TIGR02917 273 QKKNYEDARETLQDALKSAPEYLPAL 298
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 595-658 9.87e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 37.63  E-value: 9.87e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 22329002 595 WHDLAHIYINLSQWRDAESCLSRSRLIAPYSSVRYHIEGVLYNRRGQLEEAMEAFTTALDIDPM 658
Cdd:COG5010  91 YYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSPL 154
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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